Page last updated: 2024-09-03

nz 107 and histamine

nz 107 has been researched along with histamine in 4 studies

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

Compound Research Comparison

Studies
(nz 107)
Trials
(nz 107)
Recent Studies (post-2010)
(nz 107)
Studies
(histamine)
Trials
(histamine)
Recent Studies (post-2010) (histamine)
90037,7181,3723,457

Protein Interaction Comparison

ProteinTaxonomynz 107 (IC50)histamine (IC50)
Histamine H1 receptorRattus norvegicus (Norway rat)0.1585
Histamine H1 receptorHomo sapiens (human)0.1585

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daikoku, M; Iwama, T; Koda, A; Nagai, H; Suda, H; Yanagihara, Y1
Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A2
Iwama, T; Koda, A; Nagai, H; Suda, H1

Other Studies

4 other study(ies) available for nz 107 and histamine

ArticleYear
Effect of NZ-107, a newly synthesized pyridazinone derivative, on antigen-induced contraction of human bronchial strips and histamine release from human lung fragments or leukocytes.
    International archives of allergy and immunology, 1992, Volume: 98, Issue:1

    Topics: Aminopyridines; Asthma; Bronchi; Bronchoconstriction; Cromolyn Sodium; Histamine; Histamine Release; Humans; In Vitro Techniques; Interleukin-3; Lung; Pyridazines; SRS-A

1992
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A

1992
Effects of NZ-107 on bronchoconstriction in guinea pigs.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:3

    Topics: Albuterol; Animals; Asthma; Bronchoconstriction; Cromolyn Sodium; Disease Models, Animal; Guinea Pigs; Histamine; Hydrocortisone; Male; Metyrapone; Platelet Activating Factor; Prednisolone; Pyridazines; Respiration; Time Factors

1992
Effect of NZ-107 on late-phase airway responses and airway hyperreactivity in guinea pigs.
    European journal of pharmacology, 1991, Jul-09, Volume: 199, Issue:3

    Topics: Aerosols; Animals; Antigens; Bronchial Hyperreactivity; Bronchoconstriction; Drug Hypersensitivity; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyridazines; Respiratory Hypersensitivity

1991