Page last updated: 2024-09-03

nnc 112 and flb 457

nnc 112 has been researched along with flb 457 in 2 studies

Compound Research Comparison

Studies (nnc 112)	Trials (nnc 112)	Recent Studies (post-2010) (nnc 112)	Studies (flb 457)	Trials (flb 457)	Recent Studies (post-2010) (flb 457)
32	3	7	104	17	30

Protein Interaction Comparison

Protein	Taxonomy	nnc 112 (IC50)	flb 457 (IC50)
D(2) dopamine receptor	Mus musculus (house mouse)		0.0012
D(2) dopamine receptor	Rattus norvegicus (Norway rat)		0.0012

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Domino, EF; Fukumoto, D; Kakiuchi, T; Nishiyama, S; Sato, K; Tsukada, H	1
Domino, EF; Fukumoto, D; Kakiuchi, T; Miyasato, K; Nishiyama, S; Tsukada, H	1

Other Studies

2 other study(ies) available for nnc 112 and flb 457

Article	Year
Chronic NMDA antagonism impairs working memory, decreases extracellular dopamine, and increases D1 receptor binding in prefrontal cortex of conscious monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:10 Topics: Animals; Behavior, Animal; Benzazepines; Benzofurans; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Macaca mulatta; Male; Memory Disorders; Memory, Short-Term; Microdialysis; Positron-Emission Tomography; Prefrontal Cortex; Protein Binding; Pyrrolidines; Radioligand Assay; Receptors, Dopamine D1; Salicylamides; Time Factors; Tritium; Wakefulness	2005
Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment with MK-801: a PET study in conscious monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:12 Topics: Animals; Benzazepines; Benzofurans; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Macaca mulatta; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Microdialysis; Nicotine; Nicotinic Agonists; Positron-Emission Tomography; Prefrontal Cortex; Pyrrolidines; Receptors, Dopamine D1; Salicylamides	2005

Article

Year

Chronic NMDA antagonism impairs working memory, decreases extracellular dopamine, and increases D1 receptor binding in prefrontal cortex of conscious monkeys.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:10

Topics: Animals; Behavior, Animal; Benzazepines; Benzofurans; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Macaca mulatta; Male; Memory Disorders; Memory, Short-Term; Microdialysis; Positron-Emission Tomography; Prefrontal Cortex; Protein Binding; Pyrrolidines; Radioligand Assay; Receptors, Dopamine D1; Salicylamides; Time Factors; Tritium; Wakefulness

2005

Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment with MK-801: a PET study in conscious monkeys.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:12

Topics: Animals; Benzazepines; Benzofurans; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Macaca mulatta; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Microdialysis; Nicotine; Nicotinic Agonists; Positron-Emission Tomography; Prefrontal Cortex; Pyrrolidines; Receptors, Dopamine D1; Salicylamides

2005