nitrites and oxyhyponitrite

nitrites has been researched along with oxyhyponitrite in 96 studies

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.04)18.7374
1990's11 (11.46)18.2507
2000's49 (51.04)29.6817
2010's32 (33.33)24.3611
2020's3 (3.13)2.80

Authors

AuthorsStudies
Chang, SK; Harrington, GW; Rothstein, M; Shergalis, WA; Swern, D; Vohra, SK1
Galagan, ME; Kalvin'sh, IIa; Kubrina, LN; Kuzmanis, IaA; Mordvintsev, PI; Vanin, AF; Vedernikov, IuI1
Feelisch, M; Grzesiok, A; Weber, H; Zamora, R1
Sagami, I; Sato, H; Shibata, Y; Shimizu, T1
De Koster, BM; Elferink, JG; Van Der Zee, J; Vansteveninck, J; Vanuffelen, BE1
Chistodoulou, D; Cook, JA; DeGraff, WG; Feelisch, M; Fukuto, J; Gamson, J; Grisham, MB; Jourd'heuil, D; Kim, S; Krishna, M; Mitchell, JB; Vodovotz, Y; Wink, DA1
DeMaster, EG; Nagasawa, HT; Redfern, B1
Christodoulou, D; Cook, JA; DeGraff, W; Feelisch, M; Gamson, J; Kim, S; Mitchell, JB; Wink, DA1
Auriol, S; Gilibert, I; Ohshima, H; Yoshie, Y1
Cammack, R; Hughes, MN1
Celan, I; Chazotte, L; Mower, HF; Ohshima, H; Pignatelli, B1
Christopher, TA; Feelisch, M; Fukuto, JM; Gao, F; Liu, GL; Lopez, BL; Ma, XL; Wink, DA1
Feelisch, M; Komarov, AM; Schmidt, HH; Wink, DA1
Buyukafsar, K; Hillen, M; Martin, W; Nelli, S1
Buyukafsar, K; Martin, W; Nelli, S1
Martin, W; McIntosh, L; Nelli, S1
Alayash, AI; Hrinczenko, BW; Mondoro, TH; Ryan, BB; Schechter, AN; Vostal, JG1
Espey, MG; Feelisch, M; Fukuto, JM; Hare, JM; Isoda, T; Kass, DA; Martignani, C; Miranda, KM; Paolocci, N; Saavedra, WF; Wink, DA1
Colton, CA; Espey, MG; Gbadegesin, M; Miranda, KM; Vicini, S; Wink, DA1
Fujise, Y; Hishida, A; Takahira, R; Yonemura, K1
Ellis, A; Li, CG; Lu, H; Rand, MJ1
De Witt, BJ; Kadowitz, PJ; Kaye, AD; Keefer, LK; Marrone, JR1
Bai, P; Bakondi, E; Gergely, P; Szabó, C; Szabó, E; Virág, L1
Ball, SL; Duncan, A; Martin, W; McPate, MJ; Nelli, S; Rafique, KM; Shahidullah, M; Strachan, PD1
de Groot, H; Kirsch, M1
Colton, CA; DeGraff, W; Espey, MG; Krishna, MC; Miranda, KM; Mitchell, JB; Thomas, DD; Wink, DA; Yamada, K1
Bains, SK; Foresti, R; Green, CJ; Hoque, M; Motterlini, R; Naughton, P1
Cook, NM; Fukuto, JM; Jackson, MI; Leal, FA; Shinyashiki, M1
Favaloro, JL; Irvine, JC; Kemp-Harper, BK1
Chiueh, CC; Helkamaa, TH; Liesi, P; Moed, M; Rauhala, P; Tuominen, RK; Väänänen, AJ; Wiksten, M1
Foresti, R; Green, CJ; Hughes, MN; Kaur, H; Motterlini, R; Naughton, P1
Fridovich, I; Liochev, SI1
Clancy, RM; Ivanova, J; Nylander, KD; Salama, G; Schor, NF; Stoyanovsky, DA1
Nylander, KD; Salama, G; Schor, NF; Stoyanovsky, DA1
Brookes, PS; Ceaser, EK; Crawford, JH; Darley-Usmar, VM; Hillson, T; Patel, RP; Ramachandran, A; Shiva, S1
Dutton, AS; Fukuto, JM; Houk, KN1
Kankuri, E; Liebkind, R; Liesi, P; Rauhala, P; Väänänen, AJ1
Abramson, J; Cheong, E; Salama, G; Stoyanovsky, DA; Tumbev, V1
Dutton, AS; Espey, MG; Ford, E; Foreman, CA; Fukuto, JM; Houk, KN; Katori, T; Mancardi, D; Miranda, KM; Paolocci, N; Ridnour, LA; Thomas, DD; Tocchetti, CG; Wink, DA1
Bari, SE; Doctorovich, F; Estrin, DA; Martí, MA1
Alberto, F; Bari, SE; Bermejo, E; Lazzari, MA; Rosenstein, RE; Sáenz, DA1
Espey, MG; Hewett, SJ; Uliasz, TF; Wink, DA1
Champion, HC; Cologna, SM; Dutton, AS; Fukuto, JM; Houk, KN; Kass, DA; Katori, T; Keefer, LK; Mancardi, D; McLendon, WJ; Miranda, KM; Paolocci, N; Ridnour, LA; Saavedra, JE; Thomas, L; Tocchetti, CG; Torres de Holding, CL; Wink, DA1
Bryan, NS; Ducrocq, C; Feelisch, M; Fernandez, BO; Peyrot, F1
Donzelli, S; Espey, MG; Fukuto, JM; King, SB; Lazzarino, G; Mancardi, D; Miranda, KM; Paolocci, N; Ridnour, LA; Thomas, DD; Tocchetti, CG; Wink, DA1
Luckhart, S; Peterson, TM1
Hukkanen, M; Kankuri, E; Rauhala, P; Salmenperä, P; Väänänen, AJ1
Aon, MA; Bers, DM; Cheng, H; Di Benedetto, G; Froehlich, JP; Gao, WD; Huke, S; Kass, DA; O'Rourke, B; Paolocci, N; Tocchetti, CG; Toscano, JP; Valdivia, HH; Wang, W; Wilson, GM; Wink, DA; Zaccolo, M1
Favaloro, JL; Kemp-Harper, BK2
Favaloro, JL; Irvine, JC; Kemp-Harper, BK; Widdop, RE1
Dai, T; Gao, WD; Kass, DA; Katori, T; Murphy, AM; Paolocci, N; Tian, Y; Tocchetti, CG1
Amatore, C; Arbault, S; Ducrocq, C; Hu, S; Tapsoba, I1
Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K; Takenouchi, Y1
Cook, NM; Schiestl, RH; Sobol, Z1
Brooks, MN; Fukuto, JM; Jackson, MI; Lu, M; Norris, AJ; Park, T; Rao, JY; Sartippour, MR1
Deumens, E; Roitberg, AE; Seabra, Gde M; Torras, J; Trickey, SB1
Cohen, RA; Colucci, WS; Evangelista, A; Lancel, S; Siwik, DA; Tong, X; Trucillo, MP; Zhang, J1
Paolocci, N; Wink, DA1
Böger, RH; Choe, CU; Donzelli, S; Espey, MG; Fischer, G; Gerloff, C; Hewett, SJ; Hummel, FC; King, SB; Lewerenz, J; Magnus, T; Schwedhelm, E; Uliasz, TF1
Beretta, M; Koesling, D; Mayer, B; Russwurm, M; Schmidt, K; Stessel, H; Wenzl, MV; Zeller, A1
Dong Gao, W; Janssen, PM; Kaludercic, N; Kass, DA; Kohr, MJ; Paolocci, N; Tocchetti, CG; Ziolo, MT1
Dora, KA; Garland, CJ; Kemp-Harper, BK; Yarova, P; Yuill, KH1
Irvine, JC; Kemp-Harper, BK; Widdop, RE1
DuMond, JF; King, SB1
Choe, CU; Donzelli, S; Gerloff, C; Lewerenz, J; Magnus, T1
Fang, Y; Li, JY; Liu, K; Yao, C; Zhao, TC; Zhou, Y1
Cline, MR; Silverman, DN; Toscano, JP; Tu, C1
Labazi, H; Tostes, RC; Webb, RC; Wynne, BM2
Chenge, J; Kuipers, DP; Louters, LL; MacDonald, GJ; Oram, DS; Salie, MJ; Scripture, JP1
Alexander, AE; Cao, AH; Irvine, JC; Kaye, DM; Kemp-Harper, BK; Lin, EQ; Love, JE; McMullen, JR; Patel, R; Ritchie, RH1
Chianelli, MS; Dorfman, D; Knott, ME; Sáenz, DA1
Bellavia, L; Bruce King, S; Ferreyra, GA; Gladwin, MT; Helms, CC; Kern, SJ; Kim-Shapiro, DB; McPhail, LC; Natanson, C; Perlegas, A; Piknova, B; Raat, NJ; Schechter, AN; Solomon, SB; Sun, J; Sweeney, D1
Farmer, PJ; Kumar, MR; Pervitsky, D; Zapata, AL1
Casagrande, R; Cunha, FQ; Cunha, TM; Ferreira, SH; Marchesi, M; Miranda, KM; Pinge-Filho, P; Schivo, IR; Souza, GR; Verri, WA; Zarpelon, AC1
Bellavia, L; Bruce King, S; DuMond, JF; Kim-Shapiro, DB; Perlegas, A1
Gattullo, D; Pagliaro, P; Penna, C1
Bell, A; Diener, M; Pouokam, E1
Cao, N; Chin, KY; Kemp-Harper, BK; Qin, C; Ritchie, RH; Woodman, OL1
Brasch, NE; Hassanin, HA; Subedi, H1
Bobko, AA; Khramtsov, VV1
Goldstein, S; Lee, W; Nasef, MO; Samuni, U; Yadav, R1
Andrews, KL; Chin-Dusting, JP; Farry, J; Jefferis, AM; Kemp-Harper, BK; Lumsden, NG1
Kong, X; Lu, J; Terskikh, V; Wu, G1
Cao, N; Chin, KY; Michel, L; Qin, CX; Ritchie, RH; Woodman, OL1
Bian, JS; Cao, X; Ding, L; Wen, Z; Wu, Z; Zhou, Y1
Bordignon, J; Casagrande, R; Domiciano, TP; Fattori, V; Figueiredo, F; Miranda, KM; Mizokami, SS; Pelayo, JS; Pinho-Ribeiro, FA; Ruiz-Miyazawa, KW; Staurengo-Ferrari, L; Verri, WA1
Carneiro, ZN; Labazi, H; Tostes, RC; Webb, RC; Wynne, BM1
Flores-Mireles, AL; Giedroc, DP; Hultgren, SJ; Peng, H; Shen, J; Trinidad, JC; Walsh, BJC; Zhang, Y1
Chen, CY; Chen, YJ; Liaw, WF; Palanisamy, S; Tsai, FT; Wang, YL; Wang, YM1
Adamus, J; Gerbich, A; Jarmoc, D; Kramkowski, K; Leszczyńska, A; Marcinek, A; Michalski, R; Rostkowski, M; Sikora, A; Smulik-Izydorczyk, R1
Du, J; Fan, J; Long, S; Peng, X; Shao, K; Sun, W; Yang, M1
Baidanoff, FM; Chiesa, JJ; Doctorovich, F; Golombek, DA; Plano, SA; Suarez, SÁ; Trebucq, LL1
Anderson, D; Deo, M; Horowitz, JD; Kemp-Harper, BK; Li, JC; Li, M; Marshall, SA; Qin, CX; Ritchie, RH; Velagic, A; Woodman, OL1
Pouokam, E1

Reviews

3 review(s) available for nitrites and oxyhyponitrite

ArticleYear
The chemistry of nitroxyl-releasing compounds.
    Antioxidants & redox signaling, 2011, May-01, Volume: 14, Issue:9

    Topics: Azo Compounds; Cyanamide; Hydroxamic Acids; Molecular Structure; Nitrites; Nitrogen Oxides; Nitroso Compounds; Sulfonamides

2011
Nitroxyl in the central nervous system.
    Antioxidants & redox signaling, 2011, May-01, Volume: 14, Issue:9

    Topics: Animals; Calcium; Central Nervous System; Humans; Nitric Oxide Synthase Type I; Nitrites; Nitrogen Oxides; Oxidative Stress

2011
Nitroglycerine and sodium trioxodinitrate: from the discovery to the preconditioning effect.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2013, Volume: 14, Issue:10

    Topics: Animals; Cardiovascular Agents; History, 19th Century; History, 20th Century; Humans; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Signal Transduction; Vasodilator Agents

2013

Other Studies

93 other study(ies) available for nitrites and oxyhyponitrite

ArticleYear
Accelerating effect of ascorbic acid on N-nitrosamine formation and nitrosation by oxyhyponitrite.
    Cancer research, 1979, Volume: 39, Issue:10

    Topics: Ascorbic Acid; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Nitrites; Nitrosamines; Polarography

1979
[Angeli salt as a producer of nitrogen oxide in animal tissues].
    Biokhimiia (Moscow, Russia), 1990, Volume: 55, Issue:8

    Topics: Animals; Blood Pressure; Electron Spin Resonance Spectroscopy; Free Radicals; Hemoglobins; Male; Mice; Nitric Oxide; Nitrites; Nitrogen Oxides; Nitroglycerin; Nitroprusside; Rats

1990
Oxidative release of nitric oxide accounts for guanylyl cyclase stimulating, vasodilator and anti-platelet activity of Piloty's acid: a comparison with Angeli's salt.
    The Biochemical journal, 1995, Dec-01, Volume: 312 ( Pt 2)

    Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Hydroxamic Acids; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Sulfonamides; Swine; Swine, Miniature; Vasodilation; Vasodilator Agents

1995
Interaction of Angeli's salt with cytochrome P450 1A2 distal mutants: an optical absorption spectral study.
    Biochimica et biophysica acta, 1997, Nov-14, Volume: 1343, Issue:1

    Topics: Animals; Cytochrome P-450 CYP1A2; Mutation; Nitrites; Protein Binding; Rats; Saccharomyces cerevisiae

1997
Intracellular but not extracellular conversion of nitroxyl anion into nitric oxide leads to stimulation of human neutrophil migration.
    The Biochemical journal, 1998, Mar-01, Volume: 330 ( Pt 2)

    Topics: Chemotaxis, Leukocyte; Cyclic GMP; Free Radicals; Humans; In Vitro Techniques; Methionine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidants

1998
The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO.
    Archives of biochemistry and biophysics, 1998, Mar-01, Volume: 351, Issue:1

    Topics: Animals; Arginine; Buthionine Sulfoximine; Cell Death; Cell Line; Cricetinae; Cricetulus; Cyclic N-Oxides; DNA Damage; Ferricyanides; Fibroblasts; Free Radical Scavengers; Free Radicals; Glutathione; Lung; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrogen Oxides; Spin Labels

1998
Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide.
    Biochemical pharmacology, 1998, Jun-15, Volume: 55, Issue:12

    Topics: Alcoholism; Aldehyde Dehydrogenase; Antioxidants; Cyanamide; Humans; Nitrites; Nitrogen Oxides

1998
Redox generation of nitric oxide to radiosensitize hypoxic cells.
    International journal of radiation oncology, biology, physics, 1998, Nov-01, Volume: 42, Issue:4

    Topics: Animals; Cell Hypoxia; Cell Line; Cricetinae; Cyclic N-Oxides; Ferricyanides; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Radiation-Sensitizing Agents; Spin Labels

1998
Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion.
    Free radical biology & medicine, 1998, Volume: 25, Issue:9

    Topics: Antioxidants; Chromatography, High Pressure Liquid; DNA Damage; DNA, Single-Stranded; Flavins; Free Radical Scavengers; Free Radicals; Guanine; Molecular Structure; Nitrates; Nitric Oxide; Nitrites; Oxidants; Phenols; Plasmids

1998
Synthesis, chemistry, and applications of nitroxyl ion releasers sodium trioxodinitrate or Angeli's salt and Piloty's acid.
    Methods in enzymology, 1999, Volume: 301

    Topics: Hydroxamic Acids; Nitric Oxide; Nitrites; Sulfonamides

1999
Analysis of 3-nitrotyrosine in biological fluids and protein hydrolyzates by high-performance liquid chromatography using a postseparation, on-line reduction column and electrochemical detection: results with various nitrating agents.
    Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:2

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Hypochlorous Acid; Indicators and Reagents; Molsidomine; Nitrates; Nitrites; Nitrogen Oxides; Serum Albumin, Bovine; Sodium Nitrite; Spectrophotometry, Ultraviolet; Spermine; Tyrosine

1999
Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Dec-07, Volume: 96, Issue:25

    Topics: Acetylcholine; Animals; Endothelium, Vascular; Glutathione; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Nitric Oxide; Nitrites; Nitrogen Oxides; Nitroso Compounds; Oxidation-Reduction; Rabbits; S-Nitrosoglutathione

1999
Electron-paramagnetic resonance spectroscopy using N-methyl-D-glucamine dithiocarbamate iron cannot discriminate between nitric oxide and nitroxyl: implications for the detection of reaction products for nitric oxide synthase.
    Free radical biology & medicine, 2000, Mar-01, Volume: 28, Issue:5

    Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Free Radicals; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrogen Oxides; Sorbitol; Spin Labels; Superoxide Dismutase; Thiocarbamates

2000
Oxidation of nitroxyl anion to nitric oxide by copper ions.
    British journal of pharmacology, 2000, Volume: 131, Issue:2

    Topics: Analysis of Variance; Ascorbic Acid; Chelating Agents; Copper; Enzymes; Iron Compounds; Manganese Compounds; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Zinc Compounds

2000
Formation of nitric oxide from nitroxyl anion: role of quinones and ferricytochrome c.
    British journal of pharmacology, 2001, Volume: 132, Issue:1

    Topics: Animals; Aorta, Thoracic; Cytochrome c Group; Electron Transport Complex III; In Vitro Techniques; Male; Methacrylates; Monophenol Monooxygenase; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Quinones; Rats; Rats, Wistar; Thiazoles; Tyrosine; Ubiquinone; Vasodilation; Vasodilator Agents

2001
Role of copper ions and cytochrome P450 in the vasodilator actions of the nitroxyl anion generator, Angeli's salt, on rat aorta.
    European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3

    Topics: Animals; Aorta; Chelating Agents; Chlorides; Copper Sulfate; Cuprizone; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Edetic Acid; Estradiol; Free Radical Scavengers; In Vitro Techniques; Male; Manganese Compounds; Nitric Oxide Donors; Nitrites; Oxidation-Reduction; Penicillamine; Phenanthrolines; Proadifen; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Azide; Superoxide Dismutase; Vasodilation

2001
Biological action of nitric oxide donor compounds on platelets from patients with sickle cell disease.
    British journal of haematology, 2001, Volume: 112, Issue:4

    Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Case-Control Studies; Cysteine; Diethylamines; Dual Specificity Phosphatase 2; Hemostatics; Humans; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroso Compounds; P-Selectin; Platelet Aggregation; Protein Phosphatase 2; Protein Tyrosine Phosphatases; S-Nitrosothiols; Sickle Cell Trait; Thrombin

2001
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Aug-28, Volume: 98, Issue:18

    Topics: Animals; Anions; Baroreflex; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cyclic GMP; Dogs; Male; Myocardial Contraction; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Peptide Fragments; Signal Transduction

2001
Nitroxyl anion regulation of the NMDA receptor.
    Journal of neurochemistry, 2001, Volume: 78, Issue:5

    Topics: Antioxidants; Cell Hypoxia; Cell Line; Chelating Agents; Glutamic Acid; Glycine; Humans; Kidney; Membrane Potentials; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxygen Consumption; Patch-Clamp Techniques; Pentetic Acid; Receptors, N-Methyl-D-Aspartate; Transfection

2001
Dexamethasone attenuates neutrophil infiltration in the rat kidney in ischemia/reperfusion injury: the possible role of nitroxyl.
    Free radical biology & medicine, 2001, Sep-15, Volume: 31, Issue:6

    Topics: Animals; Anions; Dexamethasone; Gene Expression; Glucocorticoids; Intercellular Adhesion Molecule-1; Kidney; Male; Neutrophils; Nitrites; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2001
Effects of agents that inactivate free radical NO (NO*) on nitroxyl anion-mediated relaxations, and on the detection of NO* released from the nitroxyl anion donor Angeli's salt.
    British journal of pharmacology, 2001, Volume: 134, Issue:3

    Topics: Animals; Antioxidants; Aorta, Thoracic; Benzoates; Free Radicals; Hematinics; Hydroxocobalamin; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitrites; Nitrogen Oxides; Pyrogallol; Rats; Rats, Sprague-Dawley

2001
Comparison of responses to novel nitric oxide donors in the feline pulmonary vascular bed.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Animals; Blood Pressure; Cats; Diethylamines; Dose-Response Relationship, Drug; Female; Male; Nitric Oxide Donors; Nitrites; Polyamines; Pulmonary Artery; Pulmonary Circulation; S-Nitroso-N-Acetylpenicillamine; Spermine; Sulfites

2001
Partial protection by poly(ADP-ribose) polymerase inhibitors from nitroxyl-induced cytotoxity in thymocytes.
    Free radical biology & medicine, 2001, Dec-15, Volume: 31, Issue:12

    Topics: Animals; Apoptosis; Benzamides; Caspases; Cells, Cultured; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mitochondria; Nitrates; Nitrites; Nitrogen Oxides; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protective Agents; Thymus Gland; Tyrosine

2001
Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide.
    European journal of pharmacology, 2002, Jan-18, Volume: 435, Issue:1

    Topics: Amitrole; Animals; Aorta; Catalase; Cattle; Cyanamide; Electrochemistry; Enzyme Inhibitors; Hemoglobins; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Penis; Quinoxalines; Rats; Rats, Wistar; Sodium Azide; Spectrophotometry

2002
Formation of peroxynitrite from reaction of nitroxyl anion with molecular oxygen.
    The Journal of biological chemistry, 2002, Apr-19, Volume: 277, Issue:16

    Topics: Animals; Anions; Antioxidants; Cattle; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hydrogen-Ion Concentration; Models, Chemical; Molsidomine; NAD; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Oxygen; Peroxynitrous Acid; Rhodamines; Superoxide Dismutase

2002
Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angeli's salt and synthetic peroxynitrite.
    Archives of biochemistry and biophysics, 2002, May-15, Volume: 401, Issue:2

    Topics: Animals; Benzoic Acid; Buffers; Cell Line; Cricetinae; DNA Damage; Hydroxylation; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Peroxynitrous Acid; Phenylacetates; Reactive Nitrogen Species; Rhodamines

2002
Induction of heme oxygenase 1 by nitrosative stress. A role for nitroxyl anion.
    The Journal of biological chemistry, 2002, Oct-25, Volume: 277, Issue:43

    Topics: Animals; Cell Line; Enzyme Induction; Heme Oxygenase (Decyclizing); Nitric Oxide; Nitrites; Nitrogen Oxides; Rats

2002
Nitroxyl-mediated disruption of thiol proteins: inhibition of the yeast transcription factor Ace1.
    Archives of biochemistry and biophysics, 2003, Feb-01, Volume: 410, Issue:1

    Topics: Copper; Dimerization; DNA-Binding Proteins; Nitrites; Nitrogen Oxides; Saccharomyces cerevisiae Proteins; Sulfhydryl Compounds; Transcription Factors

2003
NO- activates soluble guanylate cyclase and Kv channels to vasodilate resistance arteries.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:6

    Topics: Animals; Arteries; Benzoates; Culture Techniques; Cysteine; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Imidazoles; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Inbred WKY; Vascular Resistance; Vasodilation

2003
Angeli's salt induces neurotoxicity in dopaminergic neurons in vivo and in vitro.
    Free radical research, 2003, Volume: 37, Issue:4

    Topics: Animals; Brain; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Hydroxyl Radical; Immunohistochemistry; In Vitro Techniques; Lipid Peroxidation; Male; Neurons; Nitrites; Oxidants; Oxidation-Reduction; Oxygen; Rats; Rats, Wistar; Salicylic Acid; Substantia Nigra; Sulfhydryl Compounds; Time Factors; Tyrosine 3-Monooxygenase

2003
Interaction of bilirubin and biliverdin with reactive nitrogen species.
    FEBS letters, 2003, May-22, Volume: 543, Issue:1-3

    Topics: Anaerobiosis; Bilirubin; Biliverdine; Free Radical Scavengers; Kinetics; Nitric Oxide; Nitrites; Nitrogen Oxides; Peroxynitrous Acid; Reactive Nitrogen Species; Sulfhydryl Compounds

2003
The mode of decomposition of Angeli's salt (Na2N2O3) and the effects thereon of oxygen, nitrite, superoxide dismutase, and glutathione.
    Free radical biology & medicine, 2003, Jun-01, Volume: 34, Issue:11

    Topics: Animals; Cattle; Free Radicals; Glutathione; Humans; Nitrites; Oxidation-Reduction; Oxygen; Superoxide Dismutase

2003
Formation of nitroxyl and hydroxyl radical in solutions of sodium trioxodinitrate: effects of pH and cytotoxicity.
    The Journal of biological chemistry, 2003, Oct-31, Volume: 278, Issue:44

    Topics: Antioxidants; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disinfectants; Electron Spin Resonance Spectroscopy; Fibroblasts; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Kinetics; Models, Chemical; Nitrites; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Oxygen; Phenol; Temperature; Time Factors

2003
Effects of pH on the cytotoxicity of sodium trioxodinitrate (Angeli's salt).
    Journal of medicinal chemistry, 2004, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Male; Mice; Mice, Nude; Nitrites

2004
Mechanisms of the interaction of nitroxyl with mitochondria.
    The Biochemical journal, 2004, Apr-15, Volume: 379, Issue:Pt 2

    Topics: Animals; Cell Respiration; Cysteine; Electron Transport Complex II; Glutathione; Male; Malonates; Mitochondria; Mitochondrial Proteins; Nitric Oxide; Nitrites; Nitrogen Oxides; Rats; Rats, Sprague-Dawley

2004
Mechanisms of HNO and NO production from Angeli's salt: density functional and CBS-QB3 theory predictions.
    Journal of the American Chemical Society, 2004, Mar-31, Volume: 126, Issue:12

    Topics: Models, Chemical; Models, Molecular; Molecular Structure; Nitric Oxide; Nitrites; Nitrogen Oxides; Thermodynamics

2004
Angeli's salt and spinal motor neuron injury.
    Free radical research, 2004, Volume: 38, Issue:3

    Topics: Animals; Dizocilpine Maleate; Hydrazines; Injections, Spinal; Male; Motor Activity; Motor Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitrous Oxide; Rats; Rats, Wistar; Spinal Cord; Time Factors

2004
Nitroxyl triggers Ca2+ release from skeletal and cardiac sarcoplasmic reticulum by oxidizing ryanodine receptors.
    Cell calcium, 2005, Volume: 37, Issue:1

    Topics: Animals; Calcium Signaling; Dithiothreitol; Dogs; Dose-Response Relationship, Drug; Hydroxyl Radical; In Vitro Techniques; Muscle, Skeletal; Myocardium; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Rabbits; Reducing Agents; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Subcellular Fractions; Transport Vesicles

2005
Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH.
    Journal of the American Chemical Society, 2005, Jan-19, Volume: 127, Issue:2

    Topics: Hydrogen-Ion Concentration; Nitric Oxide Donors; Nitrites; Oxidants; Oxidation-Reduction; Oxygen; Quantum Theory; Solutions; Spectrometry, Fluorescence; Thermodynamics

2005
Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins.
    Journal of the American Chemical Society, 2005, Apr-06, Volume: 127, Issue:13

    Topics: Anaerobiosis; Hydroxamic Acids; Kinetics; Manganese; Metalloporphyrins; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Porphyrins; Solubility; Water

2005
Effect of nitroxyl on human platelets function.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:3

    Topics: Adenosine Triphosphate; Antigens, CD; Blood Platelets; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroprusside; P-Selectin; Platelet Aggregation; Platelet Membrane Glycoproteins; Tetraspanin 30; Time Factors

2005
Neurotoxicity of nitroxyl: insights into HNO and NO biochemical imbalance.
    Free radical biology & medicine, 2005, Dec-01, Volume: 39, Issue:11

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Metalloporphyrins; Mice; Neurons; Nitric Oxide; Nitrites; Nitrogen Oxides; Receptors, Glutamate; Spin Labels

2005
Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.
    Journal of medicinal chemistry, 2005, Dec-29, Volume: 48, Issue:26

    Topics: Animals; Azo Compounds; Calcitonin Gene-Related Peptide; Cardiovascular System; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Cyclic GMP; Dogs; Glutathione; Hemodynamics; Hydrazines; Lethal Dose 50; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Uric Acid

2005
N-Nitroso products from the reaction of indoles with Angeli's salt.
    Chemical research in toxicology, 2006, Volume: 19, Issue:1

    Topics: Animals; Brain; In Vitro Techniques; Male; Melatonin; Myocardium; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitrosation; Nitroso Compounds; Oxygen; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Reactive Nitrogen Species

2006
Discriminating formation of HNO from other reactive nitrogen oxide species.
    Free radical biology & medicine, 2006, Mar-15, Volume: 40, Issue:6

    Topics: Arginine; Dimerization; Glutathione; Hydroxylamine; Nitrites; Nitrogen Dioxide; Nitrogen Oxides; Peroxynitrous Acid; Reactive Nitrogen Species

2006
A mosquito 2-Cys peroxiredoxin protects against nitrosative and oxidative stresses associated with malaria parasite infection.
    Free radical biology & medicine, 2006, Mar-15, Volume: 40, Issue:6

    Topics: Amino Acid Sequence; Animals; Anopheles; Cells, Cultured; Drosophila melanogaster; Hydrazines; Hydrogen Peroxide; Insect Proteins; Malaria; Molecular Sequence Data; Nitrites; Nitrogen Oxides; Oxidative Stress; Peroxidases; Peroxiredoxins; Peroxynitrous Acid; Plasmodium berghei; Reactive Nitrogen Species; RNA Interference; Sequence Alignment; Transfection

2006
Cathepsin B is a differentiation-resistant target for nitroxyl (HNO) in THP-1 monocyte/macrophages.
    Free radical biology & medicine, 2006, Jul-01, Volume: 41, Issue:1

    Topics: Cathepsin B; Cell Differentiation; Cytotoxicity, Immunologic; Humans; Lipopolysaccharides; Macrophages; Mitochondria; NADP; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Oxygen Consumption; Peroxynitrous Acid; Polyubiquitin; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Tetradecanoylphorbol Acetate

2006
Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling.
    Circulation research, 2007, Jan-05, Volume: 100, Issue:1

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Nitrites; Nitrogen Oxides; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sulfhydryl Compounds

2007
The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature.
    Cardiovascular research, 2007, Feb-01, Volume: 73, Issue:3

    Topics: Acetylcholine; Animals; Anions; Antioxidants; Calcitonin Gene-Related Peptide; Coronary Vessels; Dose-Response Relationship, Drug; Guanylate Cyclase; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Peptide Fragments; Perfusion; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Vasodilation

2007
Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:4

    Topics: Animals; Aorta, Thoracic; Benzoates; Cyclic GMP-Dependent Protein Kinases; Cysteine; Drug Tolerance; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Imidazoles; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred WKY; Time Factors; Vasodilation

2007
Nitroxyl increases force development in rat cardiac muscle.
    The Journal of physiology, 2007, May-01, Volume: 580, Issue:Pt.3

    Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Heart; Hydrazines; In Vitro Techniques; Intracellular Membranes; Myocardial Contraction; Myocardium; Myofibrils; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Osmolar Concentration; Rats; Rats, Sprague-Dawley

2007
Angeli's salt (Na2N2O3) is a precursor of HNO and NO: a voltammetric study of the reactive intermediates released by Angeli's salt decomposition.
    ChemMedChem, 2007, Volume: 2, Issue:6

    Topics: Electrochemistry; Free Radicals; Hydrogen-Ion Concentration; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Oxygen; Peroxynitrous Acid; Salts; Spectrophotometry, Ultraviolet

2007
Insulin-induced impairment via peroxynitrite production of endothelium-dependent relaxation and sarco/endoplasmic reticulum Ca(2+)-ATPase function in aortas from diabetic rats.
    Free radical biology & medicine, 2007, Aug-01, Volume: 43, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Immunohistochemistry; Insulin; Male; Muscle, Smooth, Vascular; Nitrites; Nitroblue Tetrazolium; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tyrosine

2007
HNO induces DNA deletions in the yeast S. cerevisiae.
    Mutation research, 2008, Feb-01, Volume: 638, Issue:1-2

    Topics: Acetylcysteine; Anaerobiosis; DNA, Fungal; Mutagenicity Tests; Nitrites; Nitrogen Oxides; Recombination, Genetic; Saccharomyces cerevisiae; Sequence Deletion

2008
Nitroxyl inhibits breast tumor growth and angiogenesis.
    International journal of cancer, 2008, Apr-15, Volume: 122, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, SCID; Nitrites; Nitrogen Oxides; Transplantation, Heterologous; Vascular Endothelial Growth Factor A

2008
A versatile AMBER-Gaussian QM/MM interface through PUPIL.
    Journal of computational chemistry, 2008, Jul-30, Volume: 29, Issue:10

    Topics: Dipeptides; Models, Chemical; Nitrites; Quantum Theory; Software

2008
Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: 4-Aminopyridine; Animals; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents

2009
Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674.
    Circulation research, 2009, Mar-27, Volume: 104, Issue:6

    Topics: Adenoviridae; Animals; Antioxidants; Cell Line; Cysteine; Glutaredoxins; Glutathione; Humans; Mutation; Myocardium; Myocytes, Cardiac; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Protein Processing, Post-Translational; Rats; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Transduction, Genetic

2009
The shy Angeli and his elusive creature: the HNO route to vasodilation.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Animals; Biological Factors; Cyclic GMP; Guanylate Cyclase; Humans; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Potassium Channels, Voltage-Gated; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents

2009
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.
    Journal of neurochemistry, 2009, Volume: 110, Issue:6

    Topics: Animals; Blood Pressure; Brain Infarction; Cells, Cultured; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; F2-Isoprostanes; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Neuroprotective Agents; Nitrites; Nitrogen Oxides; Oxidative Stress; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors

2009
Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angeli's salt.
    Molecular pharmacology, 2009, Volume: 76, Issue:5

    Topics: Animals; Cattle; Cells, Cultured; Enzyme Activation; Guanylate Cyclase; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Swine

2009
Nitroxyl enhances myocyte Ca2+ transients by exclusively targeting SR Ca2+-cycling.
    Frontiers in bioscience (Elite edition), 2010, 01-01, Volume: 2, Issue:2

    Topics: Action Potentials; Analysis of Variance; Animals; Calcium; Hydroxyl Radical; Male; Mice; Myocardial Contraction; Myocytes, Cardiac; Nitrites; Nitrogen Oxides; Rats; Sarcoplasmic Reticulum

2010
A novel role for HNO in local and spreading vasodilatation in rat mesenteric resistance arteries.
    Antioxidants & redox signaling, 2011, May-01, Volume: 14, Issue:9

    Topics: Animals; Cells, Cultured; Cysteine; Electrophysiology; Guanylate Cyclase; Male; Membrane Potentials; Mesenteric Arteries; Myocytes, Smooth Muscle; Nitrites; Nitrogen Oxides; Rats; Rats, Wistar; Vasodilation

2011
Chronic administration of the HNO donor Angeli's salt does not lead to tolerance, cross-tolerance, or endothelial dysfunction: comparison with GTN and DEA/NO.
    Antioxidants & redox signaling, 2011, May-01, Volume: 14, Issue:9

    Topics: Acetylcholine; Animals; Aorta; Cyclic GMP; Diethylamines; In Vitro Techniques; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Rats

2011
Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex.
    Organic letters, 2011, Mar-18, Volume: 13, Issue:6

    Topics: Cell Line, Tumor; Copper; Coumarins; Fluorescent Dyes; Humans; Nitrites; Nitrogen Oxides; Organometallic Compounds

2011
Detection of nitroxyl (HNO) by membrane inlet mass spectrometry.
    Free radical biology & medicine, 2011, May-15, Volume: 50, Issue:10

    Topics: Hydroxamic Acids; Mass Spectrometry; Membranes, Artificial; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Sulfonamides

2011
Aorta from angiotensin II hypertensive mice exhibit preserved nitroxyl anion mediated relaxation responses.
    Pharmacological research, 2012, Volume: 65, Issue:1

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Hypertension; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; Nitrogen Oxides; Potassium Channel Blockers; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents

2012
Nitroxyl (HNO) acutely activates the glucose uptake activity of GLUT1.
    Biochimie, 2012, Volume: 94, Issue:3

    Topics: Animals; Biological Transport; Cell Line; Glucose; Glucose Transporter Type 1; Mice; Nitrites; Nitrogen Oxides

2012
Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Angiotensin II; Animals; Cardiomegaly; Cell Adhesion Molecules; Cyclic GMP; Endothelin-1; Guanylate Cyclase; Microfilament Proteins; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; Nitrites; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Rats; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Superoxides

2012
Effect of Angeli's salt on the glutamate/glutamine cycle activity and on glutamate excitotoxicity in the hamster retina.
    Neurochemistry international, 2012, Volume: 61, Issue:1

    Topics: Animals; Cricetinae; Glutamic Acid; Glutamine; Male; Mesocricetus; Nitrites; Retina

2012
Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin.
    Free radical biology & medicine, 2012, Dec-15, Volume: 53, Issue:12

    Topics: Animals; Blood Platelets; Blood Pressure; Dogs; Erythrocytes; Heart Rate; Hemolysis; Leukocytes; Methemoglobin; Nitrites; Oxidation-Reduction; Pulmonary Artery; Vasoconstriction; Vasodilator Agents

2012
A singular value decomposition approach for kinetic analysis of reactions of HNO with myoglobin.
    Journal of inorganic biochemistry, 2013, Volume: 118

    Topics: Animals; Binding, Competitive; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Horses; Hydroxamic Acids; Kinetics; Metmyoglobin; Models, Chemical; Myocardium; Myoglobin; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Protein Binding; Sulfonamides

2013
The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats.
    Neuropharmacology, 2013, Volume: 71

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Ganglia, Spinal; Hyperalgesia; Male; Neurons; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Potassium Channel Blockers; Protein Kinase Inhibitors; Rats; Rats, Wistar; Touch

2013
Nitroxyl accelerates the oxidation of oxyhemoglobin by nitrite.
    Nitric oxide : biology and chemistry, 2013, May-31, Volume: 31

    Topics: Kinetics; Methemoglobin; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Oxyhemoglobins

2013
Actions of Angeli's salt, a nitroxyl (HNO) donor, on ion transport across mucosa-submucosa preparations from rat distal colon.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Animals; Biological Transport; Cell Membrane; Cell Polarity; Chlorides; Colon; Electrophysiological Phenomena; Epithelium; Female; Fura-2; In Vitro Techniques; Intestinal Mucosa; Intracellular Space; Male; Nitrites; Nitrogen Oxides; Rats; Rats, Wistar

2013
The concomitant coronary vasodilator and positive inotropic actions of the nitroxyl donor Angeli's salt in the intact rat heart: contribution of soluble guanylyl cyclase-dependent and -independent mechanisms.
    British journal of pharmacology, 2014, Volume: 171, Issue:7

    Topics: Animals; Cardiotonic Agents; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Nitrites; Nitrogen Oxides; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors; Vasodilation; Vasodilator Agents; Ventricular Function, Left

2014
Kinetic and mechanistic studies on the reaction of the vitamin B12 complex aquacobalamin with the HNO donor Angeli's salt: Angeli's salt and HNO react with aquacobalamin.
    Inorganic chemistry, 2014, Feb-03, Volume: 53, Issue:3

    Topics: Hydroxocobalamin; Kinetics; Nitrites; Nitroso Compounds; Vitamin B 12; Vitamin B Complex

2014
Mechanistic studies of oxidative decomposition of Angeli's salt and PAPA NONOate.
    Nitric oxide : biology and chemistry, 2014, Aug-31, Volume: 40

    Topics: Hydrazines; Molecular Structure; Nitric Oxide; Nitrites; Oxidation-Reduction

2014
Synergistic activity of acetohydroxamic acid on prokaryotes under oxidative stress: the role of reactive nitrogen species.
    Free radical biology & medicine, 2014, Volume: 77

    Topics: Anti-Bacterial Agents; Bacillus subtilis; Drug Synergism; Escherichia coli; Hydrogen Peroxide; Hydroxamic Acids; Microbial Sensitivity Tests; Nitric Oxide; Nitrites; Oxidative Stress

2014
Nitroxyl: a vasodilator of human vessels that is not susceptible to tolerance.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:2

    Topics: Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Radial Artery; Receptors, Cytoplasmic and Nuclear; Saphenous Vein; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents

2015
Solid-State (17)O NMR of Oxygen-Nitrogen Singly Bonded Compounds: Hydroxylammonium Chloride and Sodium Trioxodinitrate (Angeli's Salt).
    The journal of physical chemistry. A, 2015, Jul-23, Volume: 119, Issue:29

    Topics: Anisotropy; Hydrogen Peroxide; Hydroxylamine; Magnetic Resonance Spectroscopy; Models, Chemical; Nitrites; Nitrogen; Oxygen; Oxygen Isotopes

2015
The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo.
    Pharmacological research, 2016, Volume: 104

    Topics: Animals; Cardiotonic Agents; Dobutamine; Heart; Hemodynamics; Male; Myocardial Contraction; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Rats, Sprague-Dawley; Reperfusion Injury

2016
HNO suppresses LPS-induced inflammation in BV-2 microglial cells via inhibition of NF-κB and p38 MAPK pathways.
    Pharmacological research, 2016, Volume: 111

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; HEK293 Cells; Humans; Hydrogen Sulfide; I-kappa B Kinase; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mice; Microglia; Mutation; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction; Transfection

2016
The nitroxyl donor Angeli's salt ameliorates Staphylococcus aureus-induced septic arthritis in mice.
    Free radical biology & medicine, 2017, Volume: 108

    Topics: Animals; Antioxidants; Arthritis, Infectious; Hyperalgesia; Inflammation; Lung; Male; Mice; NF-kappa B; Nitrites; Nitrogen Oxides; Oxidative Stress; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus

2017
Nitroxyl Anion Mediates Relaxation in Mesenteric Arteries from Angiotensin II Hypertensive Mice.
    Current vascular pharmacology, 2017, Volume: 16, Issue:1

    Topics: 4-Aminopyridine; Acetylcholine; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; Nitrogen Oxides; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents

2017
Angeli's Salt, a nitroxyl anion donor, reverses endothelin-1 mediated vascular dysfunction in murine aorta.
    European journal of pharmacology, 2017, Nov-05, Volume: 814

    Topics: Animals; Aorta; Endothelin-1; Male; Mice; Nitrites; Nitrogen Oxides; Singlet Oxygen; Vasoconstriction

2017
Hydrogen Sulfide Sensing through Reactive Sulfur Species (RSS) and Nitroxyl (HNO) in Enterococcus faecalis.
    ACS chemical biology, 2018, 06-15, Volume: 13, Issue:6

    Topics: Animals; Bacterial Proteins; Coenzyme A; Cysteine; Enterococcus faecalis; Female; Hydrogen Sulfide; Mice, Inbred C57BL; Nitrites; Nitrogen Oxides; Operon; Oxidoreductases Acting on Sulfur Group Donors; Repressor Proteins; Sulfides; Sulfurtransferases; Urinary Tract Infections

2018
In Vitro and in Vivo Imaging of Nitroxyl with Copper Fluorescent Probe in Living Cells and Zebrafish.
    Molecules (Basel, Switzerland), 2018, Oct-06, Volume: 23, Issue:10

    Topics: Animals; Copper; Fluorescent Dyes; Humans; Nitrites; Nitrogen Oxides; Zebrafish

2018
Decomposition of Piloty's acid derivatives - Toward the understanding of factors controlling HNO release.
    Archives of biochemistry and biophysics, 2019, Volume: 661

    Topics: Boronic Acids; Hydrogen-Ion Concentration; Hydroxamic Acids; Isomerism; Kinetics; Nitrites; Quantum Theory; Sulfonamides

2019
A nitroxyl-responsive near-infrared fluorescent chemosensor for visualizing H
    Chemical communications (Cambridge, England), 2019, Jul-18, Volume: 55, Issue:59

    Topics: Animals; Benzylidene Compounds; Cell Line, Tumor; Fluorescent Dyes; Humans; Hydrogen Sulfide; Kidney; Light; Limit of Detection; Liver; Mice; Microscopy, Fluorescence; Nitric Oxide; Nitrites; Nitrogen Oxides; Spectrometry, Fluorescence

2019
Redox and Antioxidant Modulation of Circadian Rhythms: Effects of Nitroxyl, N-Acetylcysteine and Glutathione.
    Molecules (Basel, Switzerland), 2021, Apr-26, Volume: 26, Issue:9

    Topics: Acetylcysteine; Antioxidants; Biosensing Techniques; Circadian Clocks; Circadian Rhythm; Electrochemical Techniques; Glutathione; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Photoperiod

2021
Cardioprotective actions of nitroxyl donor Angeli's salt are preserved in the diabetic heart and vasculature in the face of nitric oxide resistance.
    British journal of pharmacology, 2022, Volume: 179, Issue:16

    Topics: Animals; Diabetes Mellitus, Type 2; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Rats; Rats, Sprague-Dawley

2022
Effects of the gaseous signalling molecule nitroxyl (HNO) on myenteric neurons governing intestinal motility.
    Journal of basic and clinical physiology and pharmacology, 2023, Sep-01, Volume: 34, Issue:5

    Topics: Animals; Gases; Gastrointestinal Motility; Neurons; Nitrites; Potassium; Rats; Sulfhydryl Compounds

2023
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