nifedipine has been researched along with hydrochlorothiazide in 123 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (22.76) | 18.7374 |
| 1990's | 38 (30.89) | 18.2507 |
| 2000's | 33 (26.83) | 29.6817 |
| 2010's | 22 (17.89) | 24.3611 |
| 2020's | 2 (1.63) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Fritschka, E | 1 |
| Masenko, VP; Mazur, NA; Tomashets, EA | 1 |
| Metelitsa, VI; Ostrovskaia, TP | 1 |
| Ekeli, T; Froeland, G; Knutsen, KM; Otterstad, JE; Wasenius Soeyland, AK | 1 |
| Duda, SG; Korinteli, MO; Metelitsa, VI; Ostrovskaia, TP; Vygodin, VA | 1 |
| Babaian, AS; Dzhandzhapanian, AZ; Gurgenian, SV; Mikaelian, ES | 1 |
| Korinteli, MO; Metelitsa, VI; Ostrovskaia, TP; Vygodin, VA | 1 |
| Fineberg, NS; Luft, FC; Weinberger, MH | 1 |
| Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV | 1 |
| Maclean, D; Ramsay, LE; Richardson, PJ | 1 |
| Liepinia, DJ; Skarda, IJ; Skards, JV; Vitols, AV; Voita, DU | 1 |
| Anderson, A; Morgan, T | 1 |
| Rofman, BA | 1 |
| Ames, RP; Applegate, WB; Burris, JF; Davidov, ME; Mroczek, WJ; Ram, CV | 1 |
| Chrysant, SG; Glasser, SP; Graves, J; Koehn, DK; Rofman, B | 1 |
| Chrysant, C; Chrysant, SG; Hitchcock, A; Trus, J | 1 |
| Behr, U; Franz, IW; Ketelhut, R; Tönnesmann, U | 1 |
| Osterloh, I | 1 |
| MacGregor, GA; Markandu, ND; Sagnella, GA; Smith, SJ | 1 |
| Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W | 1 |
| Mimran, A; Ribstein, J | 2 |
| Abraham, PA; Halstenson, CE; Opsahl, JA | 1 |
| Breckenridge, AM; Grimmer, SF; Johnston, GD; Kondowe, G; Meany, B; Richardson, PJ | 1 |
| Matsubara, T; Miyamori, I; Takasaki, H; Takeda, R; Yasuhara, S | 1 |
| MacGregor, GA; Markandu, ND; Singer, DR | 1 |
| Fonteles, MC; Gadelha, MG; Menezes, AM; Rao, VS | 1 |
| Blaser, KU; Lämmle, B | 1 |
| Schoenberger, JA | 1 |
| Callender, K; Halperin, AK; Hashimoto, F; Jueng, C | 1 |
| Crook, J; Garrett, B; Gavras, H; Gavras, I; Halperin, AK; Higgins, JT; Mulinari, R; Reeves, RL; Zawada, ET | 1 |
| Burduk, P; Karwowski, J; Nartowicz, E | 1 |
| Daniels, AR; Opie, LH | 1 |
| Jain, AK; Maronde, R; McMahon, FG; Mroczek, W; Ryan, JR; Vlachakis, N | 1 |
| Corsing, C; Deck, K; Ingram, C; Stoepel, K; Vanov, SK | 1 |
| Drayer, JI; Weber, MA | 1 |
| Glasser, SP; Leibowitz, DA; McMahon, SG; Ram, CV; Schoenberger, JA; Vanov, SK | 1 |
| Carver, LA; Lee, CH; Strosberg, AM | 1 |
| Freslon, JL; Giudicelli, JF; Richer, C | 1 |
| Heidbreder, E; Heidland, A; Kirsten, R; Schafferhans, K | 1 |
| Iarema, NI; Rudyk, BI | 1 |
| Broer, M; Duda, SG; Filatova, NP; Metelitsa, VI; Mukhamedzhanova, GF; Ostrovskaia, TP; Siegrist, J; Vygodin, VA | 1 |
| Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F | 1 |
| Duda, SG; Filatova, NP; Metelitsa, VI; Ostrovskaia, TP; Vygodin, VA | 1 |
| Carroll, J; Grossman, E; Peleg, E; Rosenthal, T; Shamiss, A | 1 |
| Kirpizidis, HG; Papazachariou, GS | 1 |
| Kruse, W; Rampmaier, J; Ullrich, G; Weber, E | 1 |
| Alli, C; Avanzini, F; Bettelli, G; Colombo, F; Corso, R; Mariotti, G; Radice, M; Tognoni, G; Torri, V | 1 |
| Lou, ZJ; Sun, XL; Zhu, GL | 1 |
| Castellet, R; del Río, G; Mora-Macià, J; Ocón, J | 1 |
| Aĭvazian, TA; Duda, SG; Filatova, NP; Kondrat'ev, VV; Manoshkina, EM; Metelitsa, VI | 1 |
| Chang, CL; Poulter, NR; Sanderson, JE; Sever, PS; Thompson, AV | 1 |
| Aron, DC; Aucott, JN; Dombrowski, R; Fuehrer, SM; Laich, J; Pelecanos, E | 1 |
| Chil'tsov, VV; Ignat'ev, VG; Kukes, VG; Pavlov, SS; Pavlova, LI; Privalov, AN; Rumiantsev, AS | 1 |
| Black, HR; Dey, HM; Hoffer, P; Soufer, R; Wackers, FJ | 1 |
| Brown, MJ; Castaigne, A; de Leeuw, PW; Ebner, F; Mancia, G; Rosenthal, T; Ruilope, LM | 1 |
| Broer, M; Duda, SG; Filatova, NP; Metelitsa, VI; Mukhamedzhanova, GF; Ostrovskaia, TP; Siegrist, I; Vygodin, VA | 1 |
| Högemann, A; Jonkman, JH; Lins, R; Sennewald, R; van Heiningen, PN; van Lier, JJ | 1 |
| Hall, DR; Odendaal, HJ | 1 |
| Moulopoulos, S; Stamatelopoulos, S; Zakopoulos, N | 1 |
| Manyemba, J | 1 |
| Agabiti-Rosei, E; Corbellini, C; Monteduro, C; Muiesan, ML; Rizzoni, D; Salvetti, M; Zulli, R | 1 |
| Barr, E; Conlin, PR; Edelman, JM; Elkins, M; Liss, C; Vrecenak, AJ | 1 |
| Agabiti-Rosei, E; Brun, C; Corbellini, C; Monteduro, C; Muiesan, ML; Rizzoni, D; Salvetti, M; Zulli, R | 1 |
| Caupers, P; Damasceno, A; Polónia, J; Rafik, A; Santos, A | 1 |
| Arabidze, GG; Birkenhäger, WH; Bulpitt, CJ; Celis, H; de Leeuw, P; Dollery, CT; Duggan, J; Fagard, RH; Fletcher, AE; Gasowski, J; Kawecka-Jaszcz, K; Leonetti, G; Nachev, C; Rodico, JL; Rosenfeld, J; Safar, M; Seux, ML; Staessen, JA; Thijs, L; Tuomilehto, J; Webster, J; Yodfat, Y | 1 |
| Brown, MJ; Castaigne, A; de Leeuw, PW; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM | 1 |
| Otterstad, JE; Ruilope, LM | 1 |
| Candy, GP; Den Hond, E; Libhaber, C; Libhaber, E; Radevski, IV; Sareli, P; Skudicky, D; Staessen, JA; Valtchanova, ZP; Wang, JG | 1 |
| Motro, M; Shemesh, J | 1 |
| Gariépy, J; Levenson, J; Moyse, D; Simon, A | 1 |
| Belz, GG; Breithaupt-Grögler, K; Meurer-Witt, B; Ungethüm, W | 1 |
| Aamar, S; Ben-Ishay, D; Bursztyn, M; Ghanem, J; Perk, G | 1 |
| Kostrov, VA; Shabanov, VA; Terekhina, EV | 1 |
| Candy, G; Libhaber, E; Radevski, I; Sareli, P; Skudicky, D; Staessen, JA; Thijs, L; Tshele, E; Valtchanova, Z; Wang, JG | 1 |
| Mancia, G; Omboni, S; Parati, G | 1 |
| Ruilope, LM | 1 |
| Devereux, RB; Palmieri, V | 1 |
| Levenson, J; Simon, A | 1 |
| Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G | 1 |
| Adams, MA; Bushfield, TL; Hale, TM; Woolard, J | 1 |
| Brown, M; Castaigne, A; De Leeuw, P; Mancia, G; Palmer, C; Rosental, T; Ruilope, L; Wagener, G | 1 |
| Babikian, V; Cheng, DM; Cupples, LA; Gagnon, M; Iloputaife, I; Kiely, DK; Lipsitz, LA; Serrador, J; Sorond, F; Vyas, M | 1 |
| Boydak, B; Nalbantgil, I; Nalbantgil, S; Onder, R; Ozerkan, F; Yilmaz, H; Zoghi, M | 1 |
| Corradi, L; Fogari, R; Mugellini, A; Pasotti, C; Preti, P; Rinaldi, A; Zoppi, A | 1 |
| Adams, MA; Hale, TM; Hannan, JL; Heaton, JP; Smallegange, C | 1 |
| Jiang, YY; Shen, FM; Su, DF; Xie, HH; Zhang, XF | 1 |
| Mittal, BV; Pendse, S; Rennke, HG; Singh, AK | 1 |
| Bi, XP; Cai, XJ; Wang, L; Zhao, Z | 1 |
| Celebi, O; Kilic, T; Komsuoglu, B; Kozdag, G; Sahin, T; Ural, D; Ural, E | 1 |
| Chen, YY; Shen, FM; Su, DF; Xie, HH; Zhang, XF | 1 |
| Bai, Y; Chen, J; Fan, X; Fu, C; Han, Y; Hui, R; Li, W; Shi, Y; Song, X; Sun, K; Wang, H; Wang, Y; Wu, H; Xin, Y; Yang, T; Zhou, X | 1 |
| Brody, R; Grossman, E; Peleg, E; Sharabi, Y | 1 |
| Cameron, A; Ewen, M; Laing, RO; van Mourik, MS | 1 |
| Belotti, E; Boari, GE; de Ciuceis, C; Muiesan, ML; Paini, A; Pilu, A; Porteri, E; Rizzoni, D; Rosei, CA; Rosei, EA; Salvetti, M; Zani, F | 1 |
| Aggiusti, C; Belotti, E; de Ciuceis, C; Muiesan, ML; Paini, A; Rizzoni, D; Rosei, CA; Rosei, EA; Salvetti, M; Scotti, A | 1 |
| Akashiba, A; Furukata, S; Ishimitsu, T; Matsuoka, H; Minami, J; Nakano, N; Numabe, A; Ohno, E | 1 |
| Asgari, MM; Chan, J; Friedman, GD; Habel, LA; Warton, EM | 1 |
| Katz, MH | 1 |
| Bennett, O; Dias, Y; Fairclough, Z; Foster, K; Gossell-Williams, M; Houston, M; Wright, K | 1 |
| Farinde, A | 1 |
| Dorrance, AM; Jackson, WF; Pires, PW | 1 |
| D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F | 1 |
| Cicero, AF; Tocci, G | 1 |
| Bardeesi, ASA; Deng, L; Guo, Y; Li, C; Li, Y; Li, Z; Liu, K; Liu, S; Pei, T; Ping, S; Sheng, P; Wang, H; Wang, J; Zhou, Y | 1 |
| Dabessa, J; Fisseha, T; Gebreegzabher, B; Getachew, S; Hadgu, A; Mengesha, HG; Merha, Z; Otieno, MG; Petrucka, P; Temesgen, H; Tewodros, H; Tsegay, K; Welegerima, AH | 1 |
| Ahmad, M; Saeed, H; Saleem, Z; Tauqeer, F; Umair, M | 1 |
| Amro, F; Blackwell, SC; Chauhan, SP; Fishel Bartal, M; Lawal, D; Pedroza, C; Samuel, J; Sibai, BM | 1 |
5 review(s) available for nifedipine and hydrochlorothiazide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Nitrendipine | 1988 |
Long-term protection in at-risk hypertensive patients--a role for nifedipine GITS?
Topics: Amiloride; Arteriosclerosis; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors | 2002 |
Angiotensin converting enzyme inhibition and dihydropyridine calcium channel blockade in the treatment of left ventricular hypertrophy in arterial hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Diuretics; Drug Therapy, Combination; Enalapril; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Meta-Analysis as Topic; Nifedipine; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Time Factors; Ventricular Dysfunction, Left | 2002 |
Effects of calcium channel blockers on atherosclerosis: new insights.
Topics: Arteriosclerosis; Calcium Channel Blockers; Diuretics; Humans; Hydrochlorothiazide; Nifedipine; Sodium Chloride Symporter Inhibitors | 2002 |
65 trial(s) available for nifedipine and hydrochlorothiazide
| Article | Year |
|---|---|
Comparisons of once-daily nilvadipine with enalapril and diuretic in patients with essential hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Triamterene | 1992 |
[The efficacy of nitrendipine in patients with stable arterial hypertension. The data from a cooperative study in the USSR. The Working Group for the Cooperative Study of Nitrendipine].
Topics: Adult; Chi-Square Distribution; Drug Tolerance; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Nifedipine; Nitrendipine; Propranolol; USSR | 1992 |
Changes in left ventricular dimensions and systolic function in 100 mildly hypertensive men during one year's treatment with atenolol vs. hydrochlorothiazide and amiloride (Moduretic): a double-blind, randomized study.
Topics: Adult; Aged; Atenolol; Cardiomegaly; Double-Blind Method; Echocardiography; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Systole; Time Factors | 1992 |
[Screening of single doses of the main antihypertensive drugs at rest and during various exercise tests in patients with hypertension].
Topics: Adult; Blood Pressure; Drug Evaluation; Exercise; Exercise Test; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Placebos; Propranolol; Rest | 1991 |
[Value of isometric and dynamic exercise tests with standard drug doses for selecting long-term antihypertensive treatment with vasodilators, adrenergic beta blockaders and diuretics].
Topics: Adult; Exercise; Exercise Test; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Time Factors | 1991 |
Long-term effect of nifedipine and hydrochlorothiazide on blood pressure and sodium homeostasis at varying levels of salt intake in mildly hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Female; Homeostasis; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Renin; Sodium; Sodium, Dietary; Time Factors | 1991 |
Enalapril and nifedipine in the treatment of mild to moderate essential hypertension: a 6 month comparison.
Topics: Adolescent; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Patient Dropouts; Statistics as Topic | 1990 |
Interaction of enalapril with sodium restriction, diuretics, and slow-channel calcium-blocking drugs.
Topics: Blood Pressure; Combined Modality Therapy; Diet, Sodium-Restricted; Drug Interactions; Drug Synergism; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Random Allocation; Time Factors | 1990 |
Long-term open evaluation of amlodipine versus hydrochlorothiazide in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Pulse; Random Allocation | 1988 |
Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation; Time Factors | 1988 |
Safety and efficacy of amlodipine added to hydrochlorothiazide therapy in essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Nifedipine; Random Allocation | 1989 |
Antihypertensive effectiveness of amlodipine in combination with hydrochlorothiazide.
Topics: Alanine Transaminase; Amlodipine; Aspartate Aminotransferases; Calcium Channel Blockers; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Supination | 1989 |
[Regression of left heart hypertrophy in hypertensive patients as a result of antihypertensive therapy].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiac Output; Cardiac Volume; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Enalapril; Female; Gallopamil; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine | 1989 |
The safety of amlodipine.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Edema; Fatigue; Flushing; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nifedipine | 1989 |
Captopril: contrasting effects of adding hydrochlorothiazide, propranolol, or nifedipine.
Topics: Blood Pressure; Body Weight; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Posture; Proline; Propranolol; Renin; Time Factors | 1985 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil | 1985 |
Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nifedipine; Renin; Renin-Angiotensin System | 1989 |
Lisinopril in essential hypertension: a six month comparative study with nifedipine.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine; Random Allocation | 1987 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Nitrendipine | 1988 |
Nifedipine GITS and hydrochlorothiazide in essential hypertension.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nifedipine; Random Allocation | 1987 |
Antihypertensive effectiveness of the nifedipine gastrointestinal therapeutic system.
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Intestinal Absorption; Male; Middle Aged; Multicenter Studies as Topic; Nifedipine | 1987 |
Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs.
Topics: Adult; Amiloride; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Headache; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nifedipine; Nisoldipine; Random Allocation | 1987 |
Comparison of nitrendipine combined with low-dose hydrochlorothiazide to hydrochlorothiazide alone in mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Random Allocation; Time Factors | 1984 |
[The effect of long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents on the quality of life in patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working
Topics: Adult; Antihypertensive Agents; Azerbaijan; Captopril; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Quality of Life; Russia; Statistics as Topic; Ukraine | 1995 |
Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study.
Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Enalapril; Female; France; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Italy; Male; Middle Aged; Nifedipine; United Kingdom | 1993 |
[The long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents of patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working group of the Multicenter Captopr
Topics: Adult; Azerbaijan; Captopril; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Quality of Life; Russia; Statistics as Topic; Time Factors; Ukraine | 1995 |
Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Neurotransmitter Agents; Nifedipine; Norepinephrine; Renin; Tetrazoles | 1994 |
Comparative effects of fosinopril and nifedipine on regression of left ventricular hypertrophy in hypertensive patients: a double-blind study.
Topics: Blood Pressure; Blood Pressure Determination; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Female; Fosinopril; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine | 1995 |
Antihypertensive efficacy and tolerability of different drug regimens in isolated systolic hypertension in the elderly.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Nifedipine; Patient Satisfaction; Treatment Outcome | 1994 |
[The effect of monotherapy with nifedipine and hydrochlorothiazide on the psychological characteristics and quality of life of hypertension patients].
Topics: Adult; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Psychological Tests; Quality of Life; Remission Induction; Sexual Behavior; Time Factors | 1993 |
Comparison of nifedipine and propranolol as second line agent for hypertension in black Kenyans.
Topics: Adult; Aged; Black People; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kenya; Middle Aged; Nifedipine; Propranolol | 1993 |
Comparison of nifedipine GITS and hydrochlorothiazide in the management of elderly patients with stage I-III diastolic hypertension.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Volume; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Renal Circulation; Ventricular Function, Left | 1996 |
INSIGHT: international nifedipine GITS study intervention as a goal in hypertension treatment.
Topics: Aged; Aged, 80 and over; Amiloride; Calcium Channel Blockers; Delayed-Action Preparations; Diuretics; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; International Cooperation; Middle Aged; Nifedipine; Risk Factors; Sodium Chloride Symporter Inhibitors | 1996 |
[The Multicenter Captopril and the Quality of Life Study: the effect of antihypertensive agents from the basic groups on the quality of life of patients in different populations. The working group of the Multicenter Captopril and the Quality of Life Study
Topics: Antihypertensive Agents; Azerbaijan; Captopril; Demography; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Moscow; Nifedipine; Propranolol; Quality of Life; Russia; Ukraine; Urban Population | 1996 |
Pharmacokinetic drug interaction studies with candesartan cilexetil.
Topics: Adolescent; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Digoxin; Drug Interactions; Female; Glyburide; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine; Tetrazoles; Warfarin | 1997 |
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy.
Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Gestational Age; Humans; Hydrochlorothiazide; Hypertension; Length of Stay; Methyldopa; Nifedipine; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Treatment Outcome | 1998 |
Effect of hypotensive drugs on the circadian blood pressure pattern in essential hypertension: a comparative study.
Topics: Adrenergic beta-Antagonists; Aged; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Nifedipine; Perindopril; Sodium Chloride Symporter Inhibitors | 1997 |
A randomised crossover comparison of reserpine and sustained-release nifedipine in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Delayed-Action Preparations; Drug Costs; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Reserpine; Vasodilator Agents; Zimbabwe | 1997 |
Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Diuretics; Double-Blind Method; Female; Heart Rate; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Nifedipine; Organ Size; Sodium Chloride Symporter Inhibitors; Vascular Resistance; Ventricular Function, Left; Ventricular Remodeling | 1998 |
A study of losartan, alone or with hydrochlorothiazide vs nifedipine GITS in elderly patients with diastolic hypertension.
Topics: Aged; Aging; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Nifedipine; Treatment Outcome | 1998 |
Effect of treatment on flow-dependent vasodilation of the brachial artery in essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Arm; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Female; Humans; Hydrochlorothiazide; Hyperemia; Hypertension; Male; Middle Aged; Nifedipine; Nitroglycerin; Regional Blood Flow; Time Factors; Ultrasonography, Doppler; Vasodilator Agents | 1999 |
[The additional efficacy of the nifedipine-diuretic combination depends on the potency of the drug administered first and not the sequence of administration. A double blind study in salt-sensitive black hypertensives].
Topics: Adult; Antihypertensive Agents; Black People; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Sodium Chloride; Sodium Chloride Symporter Inhibitors | 1999 |
Systolic Hypertension in Europe (Syst-Eur) trial phase 2: objectives, protocol, and initial progress. Systolic Hypertension in Europe Investigators.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Dihydropyridines; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Europe; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Nifedipine; Prognosis; Survival Rate; Treatment Outcome | 1999 |
Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT).
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diuretics; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Life Tables; Middle Aged; Nifedipine; Prospective Studies; Risk Factors; Treatment Outcome | 2000 |
Treatment of hypertension in the very old.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Nifedipine; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Treatment Outcome | 2000 |
Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers; Diastole; Diuretics; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine; Practice Guidelines as Topic; Proportional Hazards Models; Sodium Chloride Symporter Inhibitors; South Africa; Time Factors; Treatment Outcome; Vasodilator Agents; Verapamil | 2001 |
Calcium channel blocker nifedipine slows down progression of coronary calcification in hypertensive patients compared with diuretics.
Topics: Aged; Amiloride; Calcinosis; Calcium Channel Blockers; Cardiomyopathies; Coronary Artery Disease; Disease Progression; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Longitudinal Studies; Male; Middle Aged; Nifedipine; Tomography, X-Ray Computed | 2001 |
Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Atenolol; Blood Pressure; Carotid Artery, Common; Carotid Stenosis; Disease Progression; Diuretics; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; France; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Risk Factors; Treatment Outcome; Ultrasonography; Vasodilator Agents | 2001 |
Pharmacokinetic and dynamic interactions of the angiotensin-converting enzyme inhibitor imidapril with hydrochlorothiazide, bisoprolol and nilvadipine.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Area Under Curve; Bisoprolol; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Interactions; Hemodynamics; Humans; Hydrochlorothiazide; Imidazoles; Imidazolidines; Male; Nifedipine; Sodium Chloride Symporter Inhibitors | 2001 |
[Changes in blood rheological properties in patients with hypertension].
Topics: Adrenergic beta-Antagonists; Blood; Blood Viscosity; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Hemorheology; Humans; Hydrochlorothiazide; Hypertension; Lasers; Male; Middle Aged; Nifedipine; Phospholipids; Plasmapheresis; Propranolol; Sodium Chloride Symporter Inhibitors | 2001 |
Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial.
Topics: Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diastole; Diuretics; Echocardiography; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Methyldopa; Middle Aged; Nifedipine; Patient Compliance; Regression Analysis; South Africa; Systole; Verapamil | 2002 |
Twenty-four hour ambulatory blood pressure in the International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT).
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cardiovascular Diseases; Circadian Rhythm; Diuretics; Double-Blind Method; Female; Goals; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Office Visits; Risk Factors; Sodium Chloride Symporter Inhibitors; Vasodilator Agents | 2002 |
Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT).
Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diuretics; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Nifedipine; Organizational Objectives; Treatment Outcome | 2003 |
Effects of nifedipine GITS and diuretics in isolated systolic hypertension--a subanalysis of the INSIGHT study.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Dosage Forms; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies | 2004 |
Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Cerebrovascular Circulation; Compliance; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Cerebral Artery; Nifedipine; Photoplethysmography; Prospective Studies; Ultrasonography, Doppler, Transcranial; Vascular Resistance; Vasodilator Agents | 2005 |
The effect of combination therapy on regression of left ventricular hypertrophy in cases with hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Volume; Drug Therapy, Combination; Echocardiography; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Male; Middle Aged; Nifedipine; Ventricular Remodeling | 2004 |
Effect of telmisartan/hydrochlorothiazide combination versus nifedipine GITS on ambulatory blood pressure and sympathetic activation.
Topics: Adult; Aged; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Prospective Studies; Sympathetic Nervous System; Telmisartan | 2005 |
[The effects of antidepressant treatment on efficacy of antihypertensive therapy in elderly hypertension].
Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Depressive Disorder; Female; Fluoxetine; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Treatment Outcome | 2006 |
Sex differences in blood pressure response to antihypertensive therapy in Chinese patients with hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Asian People; Atenolol; Blood Pressure; Captopril; China; Delayed-Action Preparations; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Sex Factors | 2008 |
Effect of antihypertensive treatment on circulating endothelial progenitor cells in patients with mild essential hypertension.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Endothelial Cells; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Stem Cells | 2011 |
Effects of barnidipine in comparison with hydrochlorothiazide on endothelial function, as assessed by flow mediated vasodilatation in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Brachial Artery; Calcium Channel Blockers; Endothelium, Vascular; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Vasodilation | 2011 |
Combination of angiotensin II receptor antagonist with calcium channel blocker or diuretic as antihypertensive therapy for patients with chronic kidney disease.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Nifedipine; Treatment Outcome | 2011 |
Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus.
Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Nifedipine; Telmisartan | 2015 |
Comparative effectiveness of antihypertensive drugs prescribed in Ethiopian healthcare practice: A pilot prospective, randomized, open label study.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers; Diuretics; Enalapril; Ethiopia; Female; Health Services; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Pilot Projects; Prospective Studies; Treatment Outcome | 2018 |
Oral combined hydrochlorothiazide and lisinopril vs nifedipine for postpartum hypertension: a comparative-effectiveness pilot randomized controlled trial.
Topics: Antihypertensive Agents; Bayes Theorem; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Pregnancy-Induced; Lisinopril; Nifedipine; Pilot Projects; Postpartum Period; Pregnancy | 2023 |
54 other study(ies) available for nifedipine and hydrochlorothiazide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
[The dynamics of the concentration of atrial natriuretic factor depending on changes in the arterial pressure level in patients with arterial hypertension].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Captopril; Chronic Disease; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nifedipine; Propranolol; Renin | 1992 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Infusions, Intravenous; Male; Methyldopa; Middle Aged; Nifedipine; Ventricular Function, Left; Verapamil | 1991 |
Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Volume; Cardiomegaly; Clonidine; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Kynurenine; Male; Middle Aged; Nifedipine; Propranolol; Tryptophan | 1990 |
Haemodynamic resistance of forearm vessels during prolonged drug treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Forearm; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Nifedipine; Propranolol; Vascular Resistance | 1990 |
Effect of chronic nifedipine in patients inadequately controlled by a converting enzyme inhibitor and a diuretic.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Dipeptides; Drug Resistance; Enalapril; Female; Furosemide; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Potassium; Substance Withdrawal Syndrome | 1985 |
Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Enalapril; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Potassium | 1986 |
Effects of a calcium entry blocker on cerebral circulation in essential hypertension.
Topics: Adult; Aged; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Delayed-Action Preparations; Female; Humans; Hydrochlorothiazide; Long-Term Care; Male; Middle Aged; Nifedipine; Vascular Resistance | 1987 |
Diuretics and calcium antagonists in hypertension.
Topics: Bendroflumethiazide; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Sodium Chloride Symporter Inhibitors; Verapamil | 1988 |
Effect of calcium-entry blockers on the diuretic response to hydrochlorothiazide in the rat.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Diuresis; Female; Hydrochlorothiazide; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1988 |
[Acute hyperkalemia and non-oliguric kidney failure during treatment with indomethacin, allopurinol, nifedipine, hydrochlorothiazide/amiloride, trimethoprim/sulfamethoxazole and acetylsalicylic acid].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Allopurinol; Amiloride; Aspirin; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperkalemia; Indomethacin; Male; Nifedipine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
[Nifedipine in the emergency and chronic treatment of arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Emergencies; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propranolol | 1987 |
Efficacy and safety of nitrendipine in patients with severe hypertension: a multiclinic study.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Propranolol; Time Factors | 1984 |
Safety aspects of long-term nitrendipine therapy.
Topics: Calcium Channel Blockers; Drug Therapy, Combination; Electrocardiography; Humans; Hydrochlorothiazide; Hypertension, Renal; Male; Middle Aged; Nifedipine; Nitrendipine; Potassium; Time Factors; Uric Acid | 1984 |
The calcium channel blocker nitrendipine in single- and multiple-agent antihypertensive regimens: preliminary report of a multicenter study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Propranolol; Renin; Sodium; Time Factors | 1984 |
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains | 1983 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Relationship, Drug; Hydrochlorothiazide; Hypertension; Male; Nicardipine; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents | 1980 |
Effect of diuretics and calcium antagonists on circulatory parameters and plasma catecholamines during mental stress.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Catecholamines; Diuretics; Double-Blind Method; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Male; Nifedipine; Norepinephrine; Stress, Psychological | 1983 |
[The lipid peroxidation indices of hypertension patients undergoing combined therapy with anaprilin, korinfar and hypothiazide].
Topics: Adult; Antihypertensive Agents; Antioxidants; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipid Peroxidation; Male; Middle Aged; Nifedipine; Propranolol | 1995 |
Patterns of drug compliance with medications to be taken once and twice daily assessed by continuous electronic monitoring in primary care.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Data Collection; Drug Administration Schedule; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine; Patient Compliance; Primary Health Care; Software; Triamterene | 1994 |
[Comparative analysis of several treatment methods for severe congestive heart failure].
Topics: Adult; Aged; Aged, 80 and over; Captopril; Digoxin; Drugs, Chinese Herbal; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine | 1993 |
[Relationship of the renin-angiotensin-aldosterone system with auricular natriuretic factor in its response to the action of thiazide diuretics and to nifedipine, a sustained-release calcium antagonist].
Topics: Aldosterone; Amiloride; Animals; Ants; Blood Pressure; Delayed-Action Preparations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Renin; Renin-Angiotensin System | 1994 |
Implementation of local guidelines for cost-effective management of hypertension. A trial of the firm system.
Topics: Antihypertensive Agents; Atenolol; Cost-Benefit Analysis; Female; Health Education; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Ohio; Practice Guidelines as Topic | 1996 |
[The clinical efficacy of Korinfar-retard in combination with Cordanum, triampur and Capoten in patients with arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Captopril; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines; Time Factors; Triamterene | 1996 |
The effect of the fast of Ramadan on ambulatory blood pressure in treated hypertensives.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Fasting; Female; Humans; Hydrochlorothiazide; Hypertension; Islam; Male; Middle Aged; Nifedipine; Religion and Medicine; Sleep; Verapamil | 2001 |
Persistent lowering of arterial pressure after continuous and intermittent therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Enalapril; Heart Rate; Heart Ventricles; Hydralazine; Hydrochlorothiazide; Hypertension; Losartan; Male; Nifedipine; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Vasodilator Agents | 2003 |
Impact of antihypertensive treatments on erectile responses in aging spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Enalapril; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Transplantation; Losartan; Male; Nifedipine; Penile Erection; Random Allocation; Rats; Rats, Inbred SHR; Testosterone | 2006 |
Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Aorta; Atenolol; Baroreflex; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Irbesartan; Kidney Diseases; Male; Nifedipine; Rats; Rats, Inbred SHR; Tetrazoles | 2006 |
Hematuria in a patient with class IV lupus nephritis.
Topics: Antihypertensive Agents; Biopsy; Cyclophosphamide; El Salvador; Female; Follow-Up Studies; Glomerular Basement Membrane; Glomerular Mesangium; Glucocorticoids; Hematuria; Hispanic or Latino; Humans; Hydrochlorothiazide; Hydroxychloroquine; Hypertension; Immunosuppressive Agents; Kidney Glomerulus; Lisinopril; Lupus Nephritis; Middle Aged; Nifedipine; Prednisone; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2006 |
The effect of Ramadan fasting on ambulatory blood pressure in hypertensive patients using combination drug therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Drug Therapy, Combination; Fasting; Female; Humans; Hydrochlorothiazide; Hypertension; Islam; Male; Middle Aged; Nifedipine; Religion and Medicine; Verapamil | 2008 |
Synergism of hydrochlorothiazide and nifedipine on blood pressure variability reduction and organ protection in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Calcium Channel Blockers; Drug Synergism; Hydrochlorothiazide; Hypertension, Renal; Linear Models; Male; Nifedipine; Rats; Rats, Inbred SHR | 2008 |
Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Captopril; Hydrochlorothiazide; Losartan; Mice; Nifedipine; RNA, Messenger; Telmisartan | 2009 |
Availability, price and affordability of cardiovascular medicines: a comparison across 36 countries using WHO/HAI data.
Topics: Antihypertensive Agents; Atenolol; Captopril; Cardiovascular Diseases; Cost of Illness; Developing Countries; Health Services Accessibility; Humans; Hydrochlorothiazide; Losartan; Nifedipine; World Health Organization | 2010 |
Antihypertensive drugs and lip cancer in non-Hispanic whites.
Topics: Adult; Aged; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Hypertension; Lip Neoplasms; Male; Middle Aged; Nifedipine; Risk; White People | 2012 |
Sun protection for all: but especially for those receiving certain hypertensive medications: comment on "Antihypertensive drugs and lip cancer in non-Hispanic whites".
Topics: Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Lip Neoplasms; Male; Nifedipine; White People | 2012 |
Preference of patient information leaflets over standard drug monographs by patients prescribed hydrochlorothiazide, nifedipine and enalapril.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Drug Labeling; Enalapril; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine; Pamphlets; Patient Education as Topic; Patient Preference | 2012 |
Drugs for treating hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drugs, Generic; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Prescription Drugs; Ramipril; Tetrazoles | 2013 |
Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor.
Topics: Animals; Antihypertensive Agents; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebrovascular Circulation; Cerebrum; Compliance; Eplerenone; Hydralazine; Hydrochlorothiazide; Hypertension; Middle Cerebral Artery; Mineralocorticoid Receptor Antagonists; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Mineralocorticoid; Reserpine; Spironolactone; Vascular Remodeling; Vascular Stiffness | 2015 |
Metabolic approaches to antihypertensive treatment in diabetic patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Losartan; Male; Nifedipine | 2015 |
Role of nifedipine and hydrochlorothiazide in MAPK activation and vascular smooth muscle cell proliferation and apoptosis.
Topics: Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Hydrochlorothiazide; Hypertension; In Situ Nick-End Labeling; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nifedipine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Vascular Remodeling | 2017 |
Clinical efficacy of various anti-hypertensive regimens in hypertensive women of Punjab; a longitudinal cohort study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Longitudinal Studies; Losartan; Male; Middle Aged; Nifedipine; Pakistan; Treatment Outcome | 2020 |