naloxone and dioclein
naloxone has been researched along with dioclein* in 1 studies
Other Studies
1 other study(ies) available for naloxone and dioclein
| Article | Year |
|---|---|
Analgesic effect of Dioclea grandiflora constituents in rodents.
An aqueous fraction and dioclein (5,2',5'-trihydroxy-6,7-dimethoxyflavanone) obtained from the ethanolic extract of the Dioclea grandiflora were tested for their analgesic effect in mice and rats employing acetic-induced writhing and tail flick tests, respectively. When administered intraperitoneally the two agents exhibited significant analgesic effects. The activity of both dioclein and aqueous fraction apparently involves an opiate-like mechanism, since their analgesic action was attenuated by naloxone pretreatment. Topics: Acetates; Acetic Acid; Analgesics; Animals; Chemical Fractionation; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flavanones; Flavonoids; Injections, Intraperitoneal; Male; Mice; Naloxone; Pain; Plant Extracts; Random Allocation; Rats; Rats, Wistar | 1995 |