mupirocin and embelin

mupirocin has been researched along with embelin* in 1 studies

Other Studies

1 other study(ies) available for mupirocin and embelin

ArticleYear
Domino Synthesis of Embelin Derivatives with Antibacterial Activity.
    Journal of natural products, 2016, Apr-22, Volume: 79, Issue:4

    A series of dihydropyran embelin derivatives was synthesized through a direct and highly efficient approach based on a domino Knoevenagel intramolecular hetero-Diels-Alder reaction from natural embelin (1), using unsaturated aldehydes in the presence of organocatalysts such as ethylendiamine diacetate or l-proline. The aliphatic aldehydes yielded exclusively trans adducts, while mixtures of trans and cis isomers were found in reactions with aromatic aldehydes, with the cis form always predominating. Some of the compounds obtained were active and selective against Gram-positive bacteria, including multiresistant Staphylococcus aureus clinical isolates.

    Topics: Aldehydes; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Catalysis; Gram-Positive Bacteria; Molecular Structure; Proline; Staphylococcus aureus; Stereoisomerism

2016