mk 0663 has been researched along with ketamine in 5 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (ketamine) | Trials (ketamine) | Recent Studies (post-2010) (ketamine) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 15,029 | 2,321 | 6,678 |
| Protein | Taxonomy | mk 0663 (IC50) | ketamine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 4.216 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 4.216 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 3.7762 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 3.5563 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 4.1059 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Fass, J; Gehling, M; Klammer, A; Klammer, F; Tryba, M | 1 |
| Detry, OM; Houben, AM; Joris, JL; Kaba, A; Moreau, AJ | 1 |
1 trial(s) available for mk 0663 and ketamine
| Article | Year |
|---|---|
Bilateral subcostal transversus abdominis plane block does not improve the postoperative analgesia provided by multimodal analgesia after laparoscopic cholecystectomy: A randomised placebo-controlled trial.
Topics: Abdominal Muscles; Acetaminophen; Adult; Aged; Analgesia; Analgesics, Opioid; Anesthetics; Cholecystectomy; Dexamethasone; Double-Blind Method; Etoricoxib; Female; Humans; Ketamine; Laparoscopy; Male; Middle Aged; Nerve Block; Pain Management; Pain Measurement; Pain, Postoperative; Sevoflurane; Ultrasonography, Interventional; Visceral Pain; Young Adult | 2019 |
4 other study(ies) available for mk 0663 and ketamine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[An algorithm for postoperative pain management in visceral and thoracic surgery: an observational study].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Algorithms; Amines; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Digestive System Surgical Procedures; Dipyrone; Etoricoxib; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Hernia, Inguinal; Humans; Inservice Training; Ketamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Pirinitramide; Pyridines; Quality Assurance, Health Care; Sulfones; Thoracic Surgery, Video-Assisted; Thoracic Surgical Procedures; Treatment Outcome; Young Adult | 2013 |