Compounds > midazolam

midazolam and lignans

midazolam has been researched along with lignans in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, X; Hao, H; Kang, A; Lai, L; Liu, Y; Peng, Y; Wang, G; Wang, Q; Wang, Y; Yu, G; Zheng, C; Zhou, F1
Li, WL; Su, MW; Xin, HW; Xiong, L1
Li, WL; Su, MW; Xin, HW1
Li, WL; Wu, XC; Xin, HW; Yu, AR1
Cao, Y; Ge, G; Hong, JY; Liu, Y; Wu, J; Yang, L; Zhang, Y; Zhu, L1
Cao, YF; Fang, ZZ; Gonzalez, FJ; Liu, YZ; Sun, HZ; Sun, T; Wu, JJ; Yang, K; Yin, J; Zhao, J; Zhu, ZT1

Other Studies

6 other study(ies) available for midazolam and lignans

ArticleYear
Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:12

    Topics: Administration, Oral; Animals; Area Under Curve; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Enzyme Induction; Enzyme Inhibitors; Half-Life; Herb-Drug Interactions; Hydroxylation; Injections, Intravenous; Intestines; Lignans; Liver; Male; Metabolic Clearance Rate; Microsomes; Midazolam; Rats; Rats, Sprague-Dawley; Schisandra

2009
Inhibitory effects of schisandrin A and schisandrin B on CYP3A activity.
    Methods and findings in experimental and clinical pharmacology, 2010, Volume: 32, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inhibitory Concentration 50; Lignans; Male; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Wistar; Time Factors

2010
Inhibitory effects of continuous ingestion of Schisandrin A on CYP3A in the rat.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Ketoconazole; Lignans; Male; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Sprague-Dawley

2012
In vivo effect of Schisandrin B on cytochrome P450 enzyme activity.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Jun-15, Volume: 20, Issue:8-9

    Topics: Administration, Oral; Animals; Biological Availability; Cyclooctanes; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Interactions; Ketoconazole; Lignans; Liver; Male; Medicine, Chinese Traditional; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Sprague-Dawley

2013
Deoxyschizandrin, a naturally occurring lignan, is a specific probe substrate of human cytochrome P450 3A.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:1

    Topics: Animals; Biotransformation; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Kinetics; Lignans; Male; Microsomes, Liver; Midazolam; Nifedipine; Oxidation-Reduction; Polycyclic Compounds; Rats; Rats, Wistar; Testosterone

2014
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis.
    Fitoterapia, 2017, Volume: 119

    Topics: Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dioxoles; Herb-Drug Interactions; Humans; Hydroxylation; Lignans; Midazolam; Molecular Structure; Nifedipine; Oxidation-Reduction; Schisandra; Testosterone

2017