midazolam and lignans
midazolam has been researched along with lignans in 6 studies
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chen, X; Hao, H; Kang, A; Lai, L; Liu, Y; Peng, Y; Wang, G; Wang, Q; Wang, Y; Yu, G; Zheng, C; Zhou, F | 1 |
| Li, WL; Su, MW; Xin, HW; Xiong, L | 1 |
| Li, WL; Su, MW; Xin, HW | 1 |
| Li, WL; Wu, XC; Xin, HW; Yu, AR | 1 |
| Cao, Y; Ge, G; Hong, JY; Liu, Y; Wu, J; Yang, L; Zhang, Y; Zhu, L | 1 |
| Cao, YF; Fang, ZZ; Gonzalez, FJ; Liu, YZ; Sun, HZ; Sun, T; Wu, JJ; Yang, K; Yin, J; Zhao, J; Zhu, ZT | 1 |
Other Studies
6 other study(ies) available for midazolam and lignans
| Article | Year |
|---|---|
Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Enzyme Induction; Enzyme Inhibitors; Half-Life; Herb-Drug Interactions; Hydroxylation; Injections, Intravenous; Intestines; Lignans; Liver; Male; Metabolic Clearance Rate; Microsomes; Midazolam; Rats; Rats, Sprague-Dawley; Schisandra | 2009 |
Inhibitory effects of schisandrin A and schisandrin B on CYP3A activity.
Topics: Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inhibitory Concentration 50; Lignans; Male; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Wistar; Time Factors | 2010 |
Inhibitory effects of continuous ingestion of Schisandrin A on CYP3A in the rat.
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Ketoconazole; Lignans; Male; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Sprague-Dawley | 2012 |
In vivo effect of Schisandrin B on cytochrome P450 enzyme activity.
Topics: Administration, Oral; Animals; Biological Availability; Cyclooctanes; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Interactions; Ketoconazole; Lignans; Liver; Male; Medicine, Chinese Traditional; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Sprague-Dawley | 2013 |
Deoxyschizandrin, a naturally occurring lignan, is a specific probe substrate of human cytochrome P450 3A.
Topics: Animals; Biotransformation; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Kinetics; Lignans; Male; Microsomes, Liver; Midazolam; Nifedipine; Oxidation-Reduction; Polycyclic Compounds; Rats; Rats, Wistar; Testosterone | 2014 |
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis.
Topics: Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dioxoles; Herb-Drug Interactions; Humans; Hydroxylation; Lignans; Midazolam; Molecular Structure; Nifedipine; Oxidation-Reduction; Schisandra; Testosterone | 2017 |