midazolam and curcumin

midazolam has been researched along with curcumin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Lim, LY; Tan, TM; Zhang, W1
Badmaev, V; Court, MH; Greenblatt, DJ; Hanley, MJ; Harmatz, JS; Hazarika, S; Majeed, M; Masse, G; Volak, LP1
Abe, K; Ando, O; Imaoka, T; Karibe, T1
Birangal, S; Kadari, S; Patil, PH; Pinjari, J; Puralae Channabasavaiah, J; Rao, M; Rastogi, H; Sharma, T; Shenoy, GG; Wankhede, A1
Gardner, SF; Gentry, WB; Gurley, BJ; Hubbard, MA; Khan, IA; Shah, A; Williams, DK1
Gentry, WB; Gurley, BJ; Hartsfield, F; Hubbard, MA; Swain, A; Thaden, J; Tong, Y; Williams, DK1
Gurley, BJ; Markowitz, JS; Munoz, J; Wang, X; Zhu, HJ1
Naranjo, J; Pollard, EM; Sprung, J; Warner, MA; Warner, ME; Weingarten, TN1
Arian, CM; Calamia, JC; Nguyen, JT; Paine, MF; Rettie, AE; Tanna, RS; Thummel, KE; Tian, DD1

Trials

3 trial(s) available for midazolam and curcumin

ArticleYear
Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers.
    British journal of clinical pharmacology, 2013, Volume: 75, Issue:2

    Topics: Acetaminophen; Alkaloids; Analgesics, Non-Narcotic; Area Under Curve; Benzodioxoles; Chromatography, High Pressure Liquid; Cross-Over Studies; Curcuma; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Half-Life; Humans; Hypnotics and Sedatives; Midazolam; Piperidines; Plant Extracts; Polyunsaturated Alkamides

2013
In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes.
    Clinical pharmacology and therapeutics, 2005, Volume: 77, Issue:5

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Capsules; Cimicifuga; Dietary Supplements; Drug Administration Schedule; Female; Herb-Drug Interactions; Humans; Hydrastis; Kava; Male; Midazolam; Patient Selection; Phenotype; Time Factors; Valerian

2005
Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo.
    Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:1

    Topics: Adult; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dietary Supplements; Enzyme Induction; Enzyme Inhibitors; Female; Herb-Drug Interactions; Humans; Hydrastis; Kava; Male; Midazolam; Models, Biological; Phenotype; Plant Preparations; Rifampin; Risk Assessment; Substrate Specificity

2008

Other Studies

6 other study(ies) available for midazolam and curcumin

ArticleYear
Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Celiprolol; Coloring Agents; Curcumin; Cytochrome P-450 CYP3A; Drug Interactions; Intestine, Small; Kidney; Liver; Male; Midazolam; Rats; Rats, Sprague-Dawley

2007
Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Availability; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Curcumin; Cytochrome P-450 CYP3A; Female; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Lapatinib; Macaca fascicularis; Male; Midazolam; Neoplasm Proteins; Pantoprazole; Quinazolines; Rosuvastatin Calcium; Sulfasalazine; Terfenadine

2018
Molecular dynamics simulation and in vitro evaluation of herb-drug interactions involving dietary polyphenols and CDK inhibitors in breast cancer chemotherapy.
    Phytotherapy research : PTR, 2022, Volume: 36, Issue:10

    Topics: Breast Neoplasms; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Female; Herb-Drug Interactions; Humans; Microsomes, Liver; Midazolam; Molecular Dynamics Simulation; Polyphenols; Quercetin

2022
An ex vivo approach to botanical-drug interactions: a proof of concept study.
    Journal of ethnopharmacology, 2015, Apr-02, Volume: 163

    Topics: Adult; Benzylisoquinolines; Berberine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Female; Herb-Drug Interactions; Humans; Hydrastis; Male; Microsomes, Liver; Midazolam; Plant Extracts; Silybin; Silybum marianum; Silymarin; Tolbutamide; Young Adult

2015
Serotonergic medications, herbal supplements, and perioperative serotonin syndrome.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2017, Volume: 64, Issue:9

    Topics: Aged; Curcuma; Dietary Supplements; Drug Interactions; Fentanyl; Fluoxetine; Humans; Male; Midazolam; Naloxone; Perioperative Period; Serotonin Agents; Serotonin Syndrome; Time Factors; Trazodone; Young Adult

2017
An Integrative Approach to Elucidate Mechanisms Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Understand Clinical Observations.
    The Journal of pharmacology and experimental therapeutics, 2023, Volume: 387, Issue:3

    Topics: Adult; Alkaloids; Berberine; Biological Products; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Hydrastis; Midazolam; Models, Biological

2023