Page last updated: 2024-08-17

methionine and acetaminophen

methionine has been researched along with acetaminophen in 137 studies

Research

Studies (137)

Timeframe	Studies, this research(%)	All Research%
pre-1990	83 (60.58)	18.7374
1990's	20 (14.60)	18.2507
2000's	17 (12.41)	29.6817
2010's	15 (10.95)	24.3611
2020's	2 (1.46)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Legros, J	1
Barnett, L; Cotty, VF; Marcus, AD; Maxwell, LF	1
Park, J; Prescott, LF; Proudfoot, AT; Smith, IJ; Sutherland, GR	1
Crome, P; Goulding, R; Vale, JA; Volans, GN; Widdop, B	3
Adriaenssens, P; Ballantyne, A; Park, J; Prescott, LF; Proudfoot, AT	1
Harvey, FD; Levitt, TE	1
Ameer, B; Greenblatt, DJ	1
Harbison, R; Kasantikul, V; Martin, D; Wilson, JT	1
van Zwieten, PA	1
Adam, RD; Critchley, JA; Illingworth, RN; Prescott, LF; Proudfoot, AT; Stewart, MJ	1
Crome, P; Goulding, R; Helliwell, M; Meredith, TJ; Vale, JA; Volans, GN; Widdop, B	1
Crome, P; Goulding, R; Meredith, TJ; Volans, G	1
Peterson, RG; Rumack, BH	1
Prescott, LF	3
Goulding, R; Meredith, TJ; Newman, B	1
Austin, F; Carloss, H; Forrester, J; Fuson, T	1
Forester, D	1
Hart, FE; Willson, RA	1
Marquardt, ED	1
Prior, FG	1
Drury, MI; Fitzgerald, GA	1
Schuberth, J	1
Baehrendtz, S; Werner, B	1
Douzeen, JM; Pikaar, SA; van Heijst, AN	1
Crome, P; Vale, JA; Volans, GN; Widdop, P	1
Schubert, J	1
Park, J; Prescott, LF; Proudfoot, AT	1
Chenery, R; Fisher, C; McLean, AE; Nuttall, L	1
Day, PA; McLean, AE	1
Alván, G; Evaldsson-Carlén, U; Mellström, B	1
Andersson, C; Leonhardt, T; Stubelius, L; Svedberg, S	1
Fullerton, FR; Hathcock, JN; Poirier, LA; Reicks, MM; Whittaker, P	1
Blackledge, HM; McLean, AE; Minton, NA; O'Farrell, J	1
Duquette, PH; Holtzman, JL; Lindemann, NJ; Peterson, FJ	1
Bray, GP; Tredger, JM; Williams, R	1
Ferhanoglu, B; Loose-Mitchell, DS; Sanduja, R; Tsai, AL; Wu, KK	1
Furukawa, T; Palacin, M; Perez, C; Viña, J; Viña, JR	1
Hathcock, JN; Reicks, M	1
Jollow, DJ; Price, VF	1
Boobis, AR; Davies, DS; Tee, LG	1
Armstrong, GR; Beales, D; McLean, AE	1
Meredith, TJ; Prescott, LF; Vale, JA	1
Neuvonen, PJ; Simell, O; Tokola, O	1
McLean, AE	3
Calvert, RJ; Hathcock, JN; Reicks, M	1
Davis, M	1
Hathcock, JN; Reicks, MM	2
Read, RB; Tredger, JM; Williams, R	1
Aalen, O; Ingebrigtsen, K; Nafstad, I; Skoglund, LA	1
Carenini, G; Gentili, P; Picciòla, G; Ravenna, F; Riva, M; Tempra-Gabbiati, G; Zavaglio, G	1
Hathcock, JN	1
Allen, JM; Andrews, RS; Warrander, A	1
Monteagudo, FS; Straughan, JL; van der Merwe, LP	1
Neuvonen, PJ; Simell, O; Toivonen, ML; Tokola, O	1
Ioannides, C; Pratt, S	1
Jørgensen, LN	1
Curzon, G; Davidson, AR; Kantamaneni, BD; Knell, AJ; Williams, R	1
Henry, J; Volans, G	1
Crome, P; Hamlyn, AN; Lesna, M; Meredith, T; Record, CO; Smith, PA; Volans, GN; Watson, AJ	1
Critchley, JA; Prescott, LF	1
Birkett, DJ; Drew, R; Miners, JO	1
Nielsen, I; Pedersen, RS	1
Davis, M; Smith, HM; Tredger, JM; Williams, R	2
Baars, AJ; Glazenburg, EJ; Jekel-Halsema, IM; Mulder, GJ; Scholtens, E	1
Hopkins, S	1
Black, M	1
Goulding, R; Meredith, TJ	1
Pflüger, KH	1
Breen, KJ; Bury, RW; Desmond, PV; Forge, BH; Mashford, ML; Whelan, G	1
Dayton, H; Fretthold, D; Leickly, F; Sunshine, I; Thompson, WL; Van de Graaff, WB	1
Klein-Schwartz, W; Oderda, GM	1
Gilligan, JE; Kemp, R; Pain, R; Phillips, PJ	1
Adams, RH; Dallos, V; Daniels, RG; Guest, KP; Helps, PJ; Rogers, NC; Rose, D; Volans, GN; Wiseman, HM	1
Estrela, JM; Romero, FJ; Viña, J; Viña, JR	1
Krienke, EG; von Mühlendahl, KE	1
Goulding, R; Meredith, TJ; Vale, JA	1
Ward, SJ	1
Proudfoot, AT; Vale, JA	1
Beales, D; McLean, AE	1
Dietrich, A; Ehrlich, W; Kröger, H; Kurpisz, M; Lange, R; Ohde, M	1
Spender, Q	1
Fagan, E; Wannan, G	1
Hayes, PC; Jones, AL; Krenzelok, EP; Prescott, LF; Proudfoot, AT; Vale, JA	1
Kale, R; Saha, SK	1
Braganza, JM; Leach, FN	1
Chada, N	1
MacConnachie, AM	1
Crowe, M; Wright, B	1
Bache, K; Hauschild, A; Kröger, H; Krüger, D; Ohde, M; Thefeldt, W; Voigt, WP	1
Chandra, J	1
Law, R	1
Dass, EE; Shah, KK	1
Varela-Moreiras, G	1
Bateman, DN; Dillon, JF; Macdonald, TM; Sheen, CL; Simpson, KJ	1
Buckley, N; Eddleston, M	4
Bruneau-Wack, C; Cysyk, RL; Hartman, NR; Parker, RJ; Strong, JM; Thénot, JP	1
Alsalim, W; Fadel, M	1
Buehner, G; Chang, Y; Harper, JM; Miller, RA; Sigler, R; Smith-Wheelock, M	1
Kubo, K; Saito, M; Sekine, S; Tadokoro, T	1
Heptonstall, JP	1
Bartke, A; Bonkowski, M; Chang, Y; Harper, JM; Miller, RA; Salmon, AB	1
Arslan, F; Cete, S; Yaşar, A	1
Hou, Y; Li, L; Liu, G; Tong, Y; Wei, H; Wu, L; Wu, S	1
Buckley, N; Dawson, AH; Fernandopulle, BM; Ranganathan, SS; Senarathna, SM	1
de Silva, V; Rathnayake, A	1
du Preez, FB; Geenen, S; Kenna, JG; Nijhout, HF; Reed, M; Snoep, JL; Westerhoff, HV; Wilson, ID	1
Adeniyi, FA; Anetor, JI; Iyanda, AA; Oparinde, DP	1
Buckley, N; Fernandopulle, R; Senarathna, SM; Sri Ranganathan, S	1
Adeniyi, FA; Iyanda, AA	1
Chandrasekar, B; Deobagkar-Lele, M; Gautam, R; Kumar B N, V; Nandi, D; Rakshit, S; Umapathy, S	1
Delgado, M; Garrido, F; Pacheco, M; Pajares, MA; Partearroyo, T; Pérez-Miguelsanz, J; Pérez-Sala, D	1
Anilkumar, N; Brandes, RP; Brewer, AC; Burr, S; Caldwell, A; Dew, T; Dong, X; Halket, J; Hughes, RD; Martin, D; Mistry, RK; Murray, TV; Quaglia, A; Sawyer, GJ; Schröder, K; Shah, AM; Sherwood, R	1
Antoine, DJ; Dear, JW; Park, BK	1
Buckley, NA; Dawson, AH; Isbister, GK	1
Adekola, MA; Azeez, TO; Onaolapo, AY; Onaolapo, OJ; Salami, K	1
Brok, J; Buckley, NA; Chiew, AL; Gluud, C	1
Abdel-Rahman, HM; Abdelrahman, MM; Abdelwahab, NS; Fares, MY	1
Hamdy, AM; Ibrahim, H; Merey, HA; Saad, AS	1
Binh, VN; Ha, PTT; Hue, VTP	1

Reviews

19 review(s) available for methionine and acetaminophen

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Acetaminophen. Annals of internal medicine, 1977, Volume: 87, Issue:2 Topics: Acetaminophen; Analgesia; Animals; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Double-Blind Method; Fever; Hemostasis; Humans; Kidney Diseases; Kinetics; Liver; Male; Methionine; Pain; Placebos	1977
Death in an adolescent following an overdose of acetaminophen and phenobarbital. American journal of diseases of children (1960), 1978, Volume: 132, Issue:5 Topics: Acetaminophen; Adolescent; Animals; Brain; Child; Diagnosis, Differential; Female; Gastric Lavage; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Methionine; Phenobarbital; Prognosis; Risk; Suicide; Sulfhydryl Compounds	1978
Protective agents for acetaminophen overdose. Seminars in liver disease, 1986, Volume: 6, Issue:2 Topics: Acetaminophen; Acetylcysteine; Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimetidine; Cysteamine; Glucuronates; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxides; Liver; Methionine; Necrosis; Propylthiouracil	1986
Nutrient and non-nutrient effects on drug metabolism. Drug-nutrient interactions, 1985, Volume: 4, Issue:1-2 Topics: Acetaminophen; Aged; Antioxidants; Biological Transport; Biotransformation; Carbohydrate Metabolism; Drug Interactions; Enzyme Induction; Ethanol; Fatty Liver; Humans; Kidney; Lipid Metabolism; Methionine; Minerals; Mixed Function Oxygenases; Pharmaceutical Preparations; Proteins; Research; Starvation; Vitamins	1985
The treatment of acetaminophen poisoning. Annual review of pharmacology and toxicology, 1983, Volume: 23 Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Antidotes; Aspartate Aminotransferases; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Glutathione; Humans; Liver; Methionine; Necrosis; Sulfhydryl Compounds	1983
Acetaminophen hepatotoxicity. Gastroenterology, 1980, Volume: 78, Issue:2 Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Glutathione; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Methionine	1980
Paracetamol. Postgraduate medical journal, 1980, Volume: 56, Issue:657 Topics: Acetaminophen; Acetylcysteine; Adult; Animals; Chemical and Drug Induced Liver Injury; Child; Cysteamine; Dextropropoxyphene; Humans; Infant; Kidney Diseases; Methionine	1980
Paracetamol (acetaminophen) poisoning. Lancet (London, England), 1995, Aug-26, Volume: 346, Issue:8974 Topics: Acetaminophen; Acetylcysteine; Dose-Response Relationship, Drug; Drug Overdose; Humans; Liver; Methionine	1995
As compared to Paracetamol, does the Paracetamol and Methionine combinations have better efficacy and safety and can it be used safely in the management of pyrexia associated with liver diseases? Indian pediatrics, 1999, Volume: 36, Issue:5 Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Therapy, Combination; Female; Fever; Humans; Liver Diseases; Male; Methionine; Sensitivity and Specificity	1999
Nutritional regulation of homocysteine: effects of drugs. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2001, Volume: 55, Issue:8 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Drug Interactions; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methionine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6	2001
Paracetamol toxicity: epidemiology, prevention and costs to the health-care system. QJM : monthly journal of the Association of Physicians, 2002, Volume: 95, Issue:9 Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Combinations; Drug Costs; Drug Overdose; Drug Packaging; Humans; Methionine	2002
Paracetamol (acetaminophen) poisoning. Clinical evidence, 2002, Issue:7 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine; Poisoning; Randomized Controlled Trials as Topic; Suicide Prevention; Survival Rate; Treatment Outcome	2002
Paracetamol (acetaminophen) poisoning. Clinical evidence, 2002, Issue:8 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine	2002
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Oral methionine compared with intravenous n-acetyl cysteine for paracetamol overdose. Emergency medicine journal : EMJ, 2003, Volume: 20, Issue:4 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug Overdose; Evidence-Based Medicine; Humans; Methionine	2003
Paracetamol (acetaminophen) poisoning. Clinical evidence, 2004, Issue:12 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine	2004
Paracetamol (acetaminophen) poisoning. Clinical evidence, 2005, Issue:14 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine	2005
Paracetamol (acetaminophen) poisoning. BMJ clinical evidence, 2015, Oct-19, Volume: 2015 Topics: Acetaminophen; Acetylcysteine; Charcoal; Gastric Lavage; Humans; Liver Transplantation; Methionine; Poisoning; Renal Dialysis; Treatment Outcome	2015
Interventions for paracetamol (acetaminophen) overdose. The Cochrane database of systematic reviews, 2018, 02-23, Volume: 2 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Cysteamine; Dimercaprol; Drug Overdose; Gastric Lavage; Humans; Intestinal Absorption; Liver Failure, Acute; Liver Transplantation; Methionine; Randomized Controlled Trials as Topic	2018

Trials

4 trial(s) available for methionine and acetaminophen

Article	Year
Acetaminophen. Annals of internal medicine, 1977, Volume: 87, Issue:2 Topics: Acetaminophen; Analgesia; Animals; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Double-Blind Method; Fever; Hemostasis; Humans; Kidney Diseases; Kinetics; Liver; Male; Methionine; Pain; Placebos	1977
Methionine in paracetamol tablets, a tool to reduce paracetamol toxicity. International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:9 Topics: Acetaminophen; Administration, Oral; Adult; Animals; Biological Availability; Drug Combinations; Humans; Intestinal Absorption; Kinetics; Male; Methionine; Mice; Random Allocation; Rats; Tablets	1985
Letter: Treatment of paracetamol overdosage. Lancet (London, England), 1974, Jun-08, Volume: 1, Issue:7867 Topics: Acetaminophen; Administration, Oral; Clinical Trials as Topic; Cysteamine; Humans; Methionine; Poisoning; Time Factors	1974
Methionine and cysteamine in paracetamol (acetaminophen) overdose, prospective controlled trial of early therapy. The Journal of international medical research, 1981, Volume: 9, Issue:3 Topics: Acetaminophen; Amylases; Clinical Trials as Topic; Cysteamine; Humans; Kidney; Liver; Methionine; Myocardium; Prospective Studies	1981

Other Studies

115 other study(ies) available for methionine and acetaminophen

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Animal studies--a theoretical basis for treatment. The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl Topics: Acetaminophen; Adrenergic beta-Antagonists; Animals; Antidotes; Cysteine; Disease Models, Animal; Female; Male; Methionine; Mice; Nicotinic Acids; Sulfhydryl Compounds	1976
Letter: Prevention of acetaminophen (paracetamol) poisoning. Lancet (London, England), 1975, Sep-27, Volume: 2, Issue:7935 Topics: Acetaminophen; Animals; Dogs; Methionine	1975
Editorial: Paracetamol hepatotoxicity. Lancet (London, England), 1975, Dec-13, Volume: 2, Issue:7946 Topics: Acetaminophen; Antidotes; Chemical and Drug Induced Liver Injury; Cystamine; Drug Evaluation; Glutathione; Humans; Methionine	1975
Cysteamine, methionine, and penicillamine in the treatment of paracetamol poisoning. Lancet (London, England), 1976, Jul-17, Volume: 2, Issue:7977 Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Evaluation; Female; Humans; Liver Diseases; Male; Methionine; Middle Aged; Necrosis; Penicillamine; Poisoning; Time Factors	1976
Letter: Treatment of paracetamol overdose. Lancet (London, England), 1976, Aug-14, Volume: 2, Issue:7981 Topics: Acetaminophen; Cysteamine; Drug Evaluation; Humans; Methionine; Suicide, Attempted	1976
Oral methionine in the treatment of severe paracetamol (Acetaminophen) overdose. Lancet (London, England), 1976, Oct-16, Volume: 2, Issue:7990 Topics: Acetaminophen; Administration, Oral; Antidotes; Chemical and Drug Induced Liver Injury; Drug Evaluation; Gastric Lavage; Humans; Methionine; Time Factors	1976
Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine. Lancet (London, England), 1977, Aug-27, Volume: 2, Issue:8035 Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Evaluation; Female; Follow-Up Studies; Humans; Infusions, Parenteral; Male; Methionine; Middle Aged	1977
Experimental evaluation of paracetamol antidotes. The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl Topics: Acetaminophen; Animals; Antidotes; Bile; Cysteamine; Cysteine; Ditiocarb; Glutathione; Imidazoles; In Vitro Techniques; Liver; Methionine; Mice; Rats	1976
[Therapy of paracetamol poisoning]. Nederlands tijdschrift voor geneeskunde, 1979, Feb-24, Volume: 123, Issue:8 Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Methionine	1979
Acetylcysteine for acetaminophen overdose. The Medical letter on drugs and therapeutics, 1979, Nov-30, Volume: 21, Issue:24 Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Humans; Liver; Methionine	1979
Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning. British medical journal, 1979, Nov-03, Volume: 2, Issue:6198 Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Infusions, Parenteral; Kidney Diseases; Liver Diseases; Male; Methionine; Middle Aged; Risk; Time Factors	1979
Intravenous N-acetylcysteine: the treatment of choice in paracetamol poisoning? British medical journal, 1979, Dec-01, Volume: 2, Issue:6202 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine	1979
Treatment of paracetamol poisoning. British medical journal, 1978, May-06, Volume: 1, Issue:6121 Topics: Acetaminophen; Adult; Female; Humans; Methionine	1978
Toxicity of acetaminophen overdose. JACEP, 1978, Volume: 7, Issue:5 Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans; Methionine	1978
The chief scientist reports ... prevention of hepatic necrosis following paracetamol overdosage. Health bulletin, 1978, Volume: 36, Issue:4 Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Male; Methionine; Middle Aged; Scotland	1978
Paracetamol poisoning in children. British medical journal, 1978, Aug-12, Volume: 2, Issue:6135 Topics: Acetaminophen; Adolescent; Age Factors; Child; Child, Preschool; Humans; Infant; Methionine; United Kingdom	1978
Acute acetaminophen intoxication. Southern medical journal, 1978, Volume: 71, Issue:8 Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver; Male; Methionine; Suicide, Attempted	1978
Methionine in treatment of acetaminophen poisoning. The New England journal of medicine, 1977, Apr-07, Volume: 296, Issue:14 Topics: Acetaminophen; Administration, Oral; Humans; Methionine	1977
Acetaminophen hepatotoxicity. Mayo Clinic proceedings, 1977, Volume: 52, Issue:6 Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Methionine	1977
In vitro spectral alteration of hepatic cytochrome P-450 by experimental drug injury. Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:4 Topics: Acetaminophen; Animals; Buffers; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Glutathione; In Vitro Techniques; Liver Diseases; Male; Methionine; Microsomes, Liver; Phenobarbital; Rats; Solvents	1977
Treatment of acetaminophen toxicity. American journal of hospital pharmacy, 1977, Volume: 34, Issue:8 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine	1977
Treatment of acute paracetamol poisoning. British medical journal, 1977, Sep-24, Volume: 2, Issue:6090 Topics: Acetaminophen; Humans; Methionine	1977
Paracetemol poisoning--a brief report. Irish medical journal, 1977, Oct-21, Volume: 70, Issue:15 Topics: Acetaminophen; Adult; Gastric Lavage; Glucose; Humans; Male; Methionine	1977
[Letter: Is methionine an innocent drug?]. Lakartidningen, 1976, Jun-16, Volume: 73, Issue:25 Topics: Acetaminophen; Antidotes; Drug Evaluation; Humans; Methionine	1976
[Letter: Methionine--a reply]. Lakartidningen, 1976, Jun-16, Volume: 73, Issue:25 Topics: Acetaminophen; Antidotes; Drug Evaluation; Humans; Methionine	1976
[Paracetamol poisoning]. Nederlands tijdschrift voor geneeskunde, 1976, Jul-03, Volume: 120, Issue:27 Topics: Acetaminophen; Administration, Oral; Adult; Cysteamine; Female; Humans; Injections, Intravenous; Legislation, Drug; Methionine; Netherlands; Poisoning	1976
Letter: Toxicity of paracetamol in children. British medical journal, 1976, Aug-21, Volume: 2, Issue:6033 Topics: Acetaminophen; Child; Child, Preschool; Cysteamine; Humans; Methionine	1976
[Letter: Methionine treatment]. Lakartidningen, 1976, Aug-18, Volume: 73, Issue:34 Topics: Acetaminophen; Animals; Guinea Pigs; Humans; Methionine; Poisoning; Rabbits; Rats	1976
The use of methionine for acute paracetamol poisoning. The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl Topics: Acetaminophen; Adolescent; Adult; Female; Humans; Liver; Male; Methionine; Middle Aged; Time Factors	1976
Cysteamine, L-methionine and D-penicillamine in paracetamol poisoning. The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl Topics: Acetaminophen; Cysteamine; Humans; Methionine; Penicillamine	1976
Dietary factors in renal and hepatic toxicity of paracetamol. The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl Topics: Acetaminophen; Animals; Antidotes; Diet; Dietary Fats; Humans; In Vitro Techniques; Kidney; Liver; Methionine; Rats	1976
The effect of diet on the toxicity of paracetamol and the safety of paracetamol-methionine mixtures. Biochemical pharmacology, 1975, Jan-01, Volume: 24, Issue:1 Topics: Acetaminophen; Animals; Body Weight; Caseins; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 Enzyme System; Dietary Proteins; Drug Combinations; Fasting; Glutathione; Lethal Dose 50; Liver; Male; Methionine; Necrosis; Oils; Phenobarbital; Rats; Selenium; Yeast, Dried	1975
[Paracetamol poisoning--clinical picture and treatment possibilities]. Lakartidningen, 1976, Apr-28, Volume: 73, Issue:18 Topics: Acetaminophen; Adult; Antidotes; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Drug Synergism; Female; Humans; Liver; Methionine; Oxazepam	1976
[A case of paracetamol poisoning with reversible liver damage--some reflections]. Lakartidningen, 1976, Apr-28, Volume: 73, Issue:18 Topics: Acetaminophen; Adolescent; Antidotes; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Methionine	1976
Prolonged acetaminophen ingestion by mice fed a methionine-limited diet does not affect iron-induced liver lipid peroxidation or S-adenosylmethionine. The Journal of nutrition, 1992, Volume: 122, Issue:8 Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Male; Methionine; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase	1992
The effect of therapeutic doses of paracetamol on sulphur metabolism in man. Human & experimental toxicology, 1991, Volume: 10, Issue:3 Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Humans; Male; Methionine; Middle Aged; Sulfates; Sulfur	1991
Potentiation of acute acetaminophen lethality by selenium and vitamin E deficiency in mice. The Journal of nutrition, 1992, Volume: 122, Issue:1 Topics: Acetaminophen; Animals; Body Weight; Drug Synergism; Lethal Dose 50; Liver; Male; Methionine; Mice; Mixed Function Oxygenases; Selenium; Vitamin E Deficiency	1992
S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models. Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:2 Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mortality; S-Adenosylmethionine	1992
Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells. Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-15, Volume: 88, Issue:6 Topics: Acetaminophen; Aspirin; Blotting, Northern; Blotting, Western; Endothelium, Vascular; Epoprostenol; Humans; Indomethacin; Interleukin-1; Kinetics; Methionine; Prostaglandin-Endoperoxide Synthases; RNA, Messenger	1991
Effect of oral glutathione on hepatic glutathione levels in rats and mice. The British journal of nutrition, 1989, Volume: 62, Issue:3 Topics: Acetaminophen; Acetylcysteine; Adenosine Triphosphate; Animals; Cysteine; Fasting; Glutathione; Liver; Maleates; Methionine; Mice; Rats; Rats, Inbred Strains	1989
Prolonged acetaminophen ingestion in mice: effects on the availability of methionine for metabolic functions. The Journal of nutrition, 1989, Volume: 119, Issue:7 Topics: Acetaminophen; Animals; Body Weight; Cysteine; Glutathione; Liver; Male; Methionine; Mice; Nutritive Value; Time Factors	1989
Effects of sulfur-amino acid-deficient diets on acetaminophen metabolism and hepatotoxicity in rats. Toxicology and applied pharmacology, 1989, Volume: 101, Issue:2 Topics: Acetaminophen; Amino Acids, Sulfur; Animals; Chemical and Drug Induced Liver Injury; Diet; Drug Synergism; Glutathione; Liver; Male; Metabolic Clearance Rate; Methionine; Nitrogen; Rats; Sulfates	1989
N-acetylcysteine for paracetamol overdose. Lancet (London, England), 1986, Feb-08, Volume: 1, Issue:8476 Topics: Acetaminophen; Acetylcysteine; Animals; Cricetinae; Glutathione; Humans; In Vitro Techniques; Liver; Methionine	1986
Effect of D- or L-methionine and cysteine on the growth inhibitory effects of feeding 1% paracetamol to rats. Biochemical pharmacology, 1989, Jan-15, Volume: 38, Issue:2 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; Growth; Methionine; Phenobarbital; Rats; Sulfates	1989
Why do patients still die from paracetamol poisoning? British medical journal (Clinical research ed.), 1986, Aug-09, Volume: 293, Issue:6543 Topics: Acetaminophen; Acetylcysteine; Adult; Child, Preschool; Gastric Lavage; Humans; Methionine	1986
Why not add methionine to paracetamol tablets? British medical journal (Clinical research ed.), 1986, Oct-11, Volume: 293, Issue:6552 Topics: Acetaminophen; Animals; Antidotes; Drug Combinations; Humans; Methionine	1986
Why do patients still die from paracetamol poisoning? British medical journal (Clinical research ed.), 1986, Nov-01, Volume: 293, Issue:6555 Topics: Acetaminophen; Antidotes; Drug Combinations; Humans; Legislation, Drug; Methionine; United Kingdom	1986
Effects of prolonged acetaminophen ingestion and dietary methionine on mouse liver glutathione. Drug-nutrient interactions, 1988, Volume: 5, Issue:4 Topics: Acetaminophen; Alanine Transaminase; Aniline Hydroxylase; Animals; Cysteine; Diet; Female; Glutathione; Liver; Male; Methionine; Mice; Microsomes, Liver	1988
Paracetamol + methionine: pameton. Drug and therapeutics bulletin, 1987, Dec-14, Volume: 25, Issue:25 Topics: Acetaminophen; Analgesics; Drug Combinations; Humans; Methionine	1987
Effects of methionine deficiency and ethanol ingestion on acetaminophen metabolism in mice. The Journal of nutrition, 1987, Volume: 117, Issue:3 Topics: Acetaminophen; Acetylcysteine; Aniline Hydroxylase; Animals; Body Weight; Diet; Ethanol; Glutathione; Male; Methionine; Mice; Microsomes, Liver; Protein Biosynthesis; Sulfates	1987
Analysis of factors responsible for continuing mortality after paracetamol overdose. Human toxicology, 1986, Volume: 5, Issue:3 Topics: Acetaminophen; Acetylcysteine; Adolescent; Alcoholism; Antidotes; Dextropropoxyphene; Disseminated Intravascular Coagulation; Drug Combinations; Hepatic Encephalopathy; Humans; Liver Function Tests; Male; Methionine; Retrospective Studies	1986
Efficacy of paracetamol-esterified methionine versus cysteine or methionine on paracetamol-induced hepatic GSH depletion and plasma ALAT level in mice. Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18 Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Drug Compounding; Glutathione; Liver; Male; Methionine; Mice; Time Factors	1986
[Methionine derivatives with liver protecting activity]. Il Farmaco; edizione scientifica, 1986, Volume: 41, Issue:10 Topics: Acetaminophen; Alcoholic Intoxication; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Ethionine; Methionine; Mice; Rats	1986
Incorporation of radiolabelled amino acids into the sulphur-containing metabolites of paracetamol by the hamster. Xenobiotica; the fate of foreign compounds in biological systems, 1985, Volume: 15, Issue:11 Topics: Acetaminophen; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cricetinae; Cysteine; Male; Mesocricetus; Methionine; Serine	1985
The choice between intravenous N-acetylcysteine and oral methionine in paracetamol poisoning. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Mar-01, Volume: 69, Issue:5 Topics: Acetaminophen; Administration, Oral; Cystine; Humans; Injections, Intravenous; Methionine	1986
Mechanism of the protective action of n-acetylcysteine and methionine against paracetamol toxicity in the hamster. Archives of toxicology, 1985, Volume: 57, Issue:3 Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Glutathione; Liver; Male; Mesocricetus; Methionine; Organ Size	1985
[Survival after self-poisoning with 80 grams of paracetamol]. Ugeskrift for laeger, 1985, Nov-04, Volume: 147, Issue:45 Topics: Acetaminophen; Acetylcysteine; Female; Humans; Methionine; Middle Aged; Prognosis	1985
Letter: Prevention of paracetamol poisoning. Lancet (London, England), 1974, Apr-20, Volume: 1, Issue:7860 Topics: Acetaminophen; Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Combinations; Humans; Methionine; Poisoning; Rats	1974
Dopamine and serotonin metabolism in hepatic encephalopathy. British medical journal, 1974, Mar-23, Volume: 1, Issue:5907 Topics: Acetaminophen; Acute Disease; Adult; Aged; Brain; Dopamine; Fatty Acids, Nonesterified; Female; Halothane; Hepatic Encephalopathy; Hepatitis A; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methionine; Middle Aged; Phenylalanine; Serotonin; Tryptophan; Tyrosine	1974
New approaches in managing drug overdosage and poisoning. British medical journal (Clinical research ed.), 1983, Jul-23, Volume: 287, Issue:6387 Topics: Acetaminophen; Acetylcysteine; Adrenergic beta-Antagonists; Adult; Analgesics, Opioid; Child; Cholinesterase Inhibitors; Glucagon; Humans; Immunotherapy; Intestinal Absorption; Methionine; Naloxone; Physostigmine; Poisoning; Poisons; Self Administration	1983
ABC of poisoning. Analgesics: II--Paracetamol. British medical journal (Clinical research ed.), 1984, Oct-06, Volume: 289, Issue:6449 Topics: Acetaminophen; Acetylcysteine; Analgesics; Diagnosis; Humans; Ipecac; Methionine; Therapeutic Irrigation; Time Factors	1984
Mechanism of action of paracetamol protective agents in mice in vivo. Biochemical pharmacology, 1984, Oct-01, Volume: 33, Issue:19 Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Buthionine Sulfoximine; Cysteamine; Cysteine; Glutathione; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H	1984
Effects of dietary methionine and ethanol on acetaminophen hepatotoxicity in mice. Drug-nutrient interactions, 1984, Volume: 3, Issue:1 Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Body Weight; Diet; Ethanol; Glutathione; Glutathione Transferase; Liver; Male; Methionine; Mice	1984
[Paracetamol poisoning. Specific treatment with methionine or N-acetylcysteine?]. Ugeskrift for laeger, 1984, May-14, Volume: 146, Issue:20 Topics: Acetaminophen; Acetylcysteine; Antidotes; Humans; Methionine	1984
In vitro interactions of sulfur-containing compounds with the hepatic mixed-function oxidase system in mice: effects on paracetamol activation and covalent binding. Toxicology and applied pharmacology, 1981, Jun-15, Volume: 59, Issue:1 Topics: Acetaminophen; Animals; In Vitro Techniques; Liver; Methionine; Mice; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Spectrum Analysis; Sulfhydryl Compounds	1981
Effects of variation in the dietary supply of cysteine and methionine on liver concentration of glutathione and "active sulfate" (PAPS) and serum levels of sulfate, cystine, methionine and taurine: relation to the metabolism of acetaminophen. The Journal of nutrition, 1983, Volume: 113, Issue:7 Topics: Acetaminophen; Animals; Cysteine; Cystine; Diet; Glutathione; Growth; Liver; Male; Methionine; Phosphoadenosine Phosphosulfate; Rats; Rats, Inbred Strains; Sulfates; Taurine	1983
Paracetamol. Nursing mirror, 1980, Feb-14, Volume: 150, Issue:7 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine; Poisoning	1980
[Toxicology and therapy of paracetamol poisoning]. Der Internist, 1980, Volume: 21, Issue:12 Topics: Acetaminophen; Acetylcysteine; Cysteamine; Drug Interactions; Ethanol; Gastric Lavage; Glutathione; Half-Life; Methionine; Phenobarbital; Poisoning	1980
Paracetamol self-poisoning: diagnosis, management, and outcome. The Medical journal of Australia, 1982, Jan-23, Volume: 1, Issue:2 Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adolescent; Adult; Australia; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Female; Hospitalization; Humans; Injections, Intravenous; Liver Diseases; Liver Function Tests; Methionine; Middle Aged; Suicide, Attempted; Time Factors	1982
Adsorbent and cathartic inhibition of enteral drug absorption. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3 Topics: Acetaminophen; Acetylcysteine; Adsorption; Animals; Cathartics; Charcoal; Chemistry, Pharmaceutical; Dogs; Female; Intestinal Absorption; Male; Methionine; Mice; Resins, Plant; Time Factors	1982
Adsorption of oral antidotes for acetaminophen poisoning (methionine and n-acetylcysteine) by activated charcoal. Clinical toxicology, 1981, Volume: 18, Issue:3 Topics: Acetaminophen; Acetylcysteine; Adsorption; Antidotes; Charcoal; Chemical Phenomena; Chemistry; Methionine	1981
Paracetamol concentrations, hepatotoxicity, and antidotes. British medical journal, 1980, Jan-12, Volume: 280, Issue:6207 Topics: Acetaminophen; Acetylcysteine; Humans; Methionine; Risk; Time Factors	1980
Vomiting in paracetamol poisoning. British medical journal, 1980, Feb-23, Volume: 280, Issue:6213 Topics: Acetaminophen; Humans; Methionine; Vomiting	1980
Effects of sulphur-containing compounds on paracetamol activation and covalent binding in a mouse hepatic microsomal system. Toxicology letters, 1980, Volume: 5, Issue:5 Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteamine; In Vitro Techniques; Male; Methionine; Mice; Microsomes, Liver; Mixed Function Oxygenases; Sulfur; Tiopronin	1980
Effect of acetaminophen (paracetamol) and its antagonists on glutathione (GSH) content in rat liver. Biochemical pharmacology, 1980, Jul-01, Volume: 29, Issue:13 Topics: Acetaminophen; Acetylcysteine; Animals; Glutathione; In Vitro Techniques; Liver; Methionine; Rats; Time Factors	1980
[Paracetamol poisoning]. Intensivmedizinische Praxis, 1980, Issue:2 Topics: Acetaminophen; Acetylcysteine; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Kidney Tubular Necrosis, Acute; Liver; Methionine; Transaminases	1980
Treatment of severe acetaminophen poisoning with intravenous acetylcysteine. Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Cysteamine; Humans; Injections, Intravenous; Liver; Methionine	1981
Treatment of acetaminophen poisoning. The use of oral methionine. Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Humans; Liver; Methionine; Time Factors	1981
Management of paracetamol poisoning. Lancet (London, England), 1995, Nov-04, Volume: 346, Issue:8984 Topics: Acetaminophen; Analgesics, Non-Narcotic; Charcoal; Drug Interactions; Drug Overdose; Humans; Intestinal Absorption; Methionine	1995
Cell injury and protection in long-term incubation of liver slices after in vivo initiation with paracetamol: cell injury after in vivo initiation with paracetamol. Toxicology, 1995, Nov-30, Volume: 103, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Carnitine; Chromatography, High Pressure Liquid; Fructose; Glutamic Acid; Glycerol; In Vitro Techniques; Injections, Intraperitoneal; L-Lactate Dehydrogenase; Liver; Male; Methionine; Phenylenediamines; Potassium; Propylene Glycol; Propylene Glycols; Rats; Rats, Wistar; Time Factors	1995
Protection from acetaminophen-induced liver damage by the synergistic action of low doses of the poly(ADP-ribose) polymerase-inhibitor nicotinamide and the antioxidant N-acetylcysteine or the amino acid L-methionine. General pharmacology, 1997, Volume: 28, Issue:2 Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Synergism; Male; Methionine; Mice; Mice, Inbred Strains; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors	1997
Reducing paracetamol overdoses. Methionine should be included in all paracetamol preparations. BMJ (Clinical research ed.), 1997, Mar-08, Volume: 314, Issue:7082 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antidotes; Drug Compounding; Drug Overdose; Humans; Methionine	1997
Public should know of efficacy of early hospital treatment of paracetamol overdose. BMJ (Clinical research ed.), 1997, Jul-26, Volume: 315, Issue:7102 Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Overdose; Health Education; Hospitalization; Humans; Methionine	1997
Should methionine be added to every paracetamol tablet? BMJ (Clinical research ed.), 1997, Aug-02, Volume: 315, Issue:7103 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antidotes; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Costs; Drug Overdose; Humans; Liver Diseases; Methionine	1997
Adding methionine to every paracetamol tablet. Paracetamol overdose is so rare in India that adding methionine would be wrong. BMJ (Clinical research ed.), 1998, Feb-07, Volume: 316, Issue:7129 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child; Child, Preschool; Drug Combinations; Drug Overdose; Humans; India; Methionine	1998
Adding methionine to way paracetamol tablet. Methionine is important in treatment of chronic pancreatitis. BMJ (Clinical research ed.), 1998, Feb-07, Volume: 316, Issue:7129 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chronic Disease; Drug Combinations; Humans; Methionine; Pancreatitis; Rats	1998
Adding methionine to every paracetamol tablet. Drugs as important as paracetamol in developing countries should not be tainted. BMJ (Clinical research ed.), 1998, Feb-07, Volume: 316, Issue:7129 Topics: Acetaminophen; Analgesics, Non-Narcotic; Developing Countries; Drug Combinations; Drug Overdose; Humans; Methionine; Sri Lanka	1998
Adding methionine to every paracetamol tablet. Plan is needed for way in which paracetamol and other analgesics are sold. BMJ (Clinical research ed.), 1998, Feb-07, Volume: 316, Issue:7129 Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Combinations; Drug Industry; Drug Overdose; Health Planning; Homocysteine; Humans; Methionine	1998
Paracetamol poisoning. Accident and emergency nursing, 1998, Volume: 6, Issue:1 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Emergency Nursing; Free Radical Scavengers; Humans; Methionine	1998
Deaths from low dose paracetamol poisoning. Use of oral methionine for overdose below threshold for acetylcysteine. BMJ (Clinical research ed.), 1998, Dec-12, Volume: 317, Issue:7173 Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Analgesics, Non-Narcotic; Antidotes; Humans; Methionine	1998
Nicotinamide and methionine reduce the liver toxic effect of methotrexate. General pharmacology, 1999, Volume: 33, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antirheumatic Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Liver Diseases; Male; Methionine; Methotrexate; Mice; Mice, Inbred DBA; Niacinamide	1999
Severity of overdose after restriction of paracetamol availability. Why hasn't strategy for minimising paracetamol poisoning been enacted? BMJ (Clinical research ed.), 2001, Mar-03, Volume: 322, Issue:7285 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Humans; Methionine; Poisoning	2001
Paracetamol and conventional antimalarial drugs induced hepatotoxicity and its protection by methionine in rats. Indian journal of experimental biology, 2000, Volume: 38, Issue:11 Topics: Acetaminophen; Animals; Antimalarials; Female; Liver; Male; Methionine; Rats	2000
Production of intracellular 35S-glutathione by rat and human hepatocytes for the quantification of xenobiotic reactive intermediates. Chemico-biological interactions, 2002, Nov-10, Volume: 142, Issue:1-2 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Radioisotopes; Chromatography, Liquid; Cystine; Glutathione; Hepatocytes; Humans; Liver; Mass Spectrometry; Methionine; Rats; Sulfur Radioisotopes	2002
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging cell, 2005, Volume: 4, Issue:3 Topics: Acetaminophen; Aging; Alanine Transaminase; Animals; Blood Glucose; Body Weight; Cataract; Diet; Energy Intake; Female; Insulin; Insulin-Like Growth Factor I; Intramolecular Oxidoreductases; L-Lactate Dehydrogenase; Liver; Longevity; Macrophage Migration-Inhibitory Factors; Methionine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxidative Stress; RNA, Messenger; T-Lymphocyte Subsets; Thyroxine	2005
Dietary docosahexaenoic acid-induced generation of liver lipid peroxides is not suppressed further by elevated levels of glutathione in ODS rats. Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:4 Topics: Acetaminophen; Animals; Ascorbic Acid; Bone Diseases, Metabolic; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Methionine; Random Allocation; Rats; Rats, Inbred Strains	2006
Time to make paracetamol with methionine available. BMJ (Clinical research ed.), 2006, Apr-01, Volume: 332, Issue:7544 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antidotes; Drug Combinations; Drug Overdose; Humans; Methionine	2006
Stress resistance and aging: influence of genes and nutrition. Mechanisms of ageing and development, 2006, Volume: 127, Issue:8 Topics: Acetaminophen; Aging; Animals; Cadmium; Caloric Restriction; Cell Line; Diet; Dwarfism; Female; Fibroblasts; Hydrogen Peroxide; Longevity; Male; Methionine; Mice; Mice, Knockout; Receptors, Somatotropin; Skin; Ultraviolet Rays	2006
An amperometric biosensor for uric acid determination prepared from uricase immobilized in polypyrrole film. Artificial cells, blood substitutes, and immobilization biotechnology, 2006, Volume: 34, Issue:3 Topics: Acetaminophen; Ascorbic Acid; Biosensing Techniques; Body Fluids; Electrochemistry; Enzyme Stability; Enzymes, Immobilized; Humans; Hydrogen-Ion Concentration; Methionine; Polymers; Pyrroles; Reproducibility of Results; Temperature; Urate Oxidase; Uric Acid	2006
Protection by bicyclol derivatives against acetaminophen-induced acute liver failure in mice and its active mechanism. Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:9 Topics: Acetaminophen; Adenosine Triphosphate; Analgesics, Non-Narcotic; Animals; Apoptosis; Apoptosis Inducing Factor; Benzodioxoles; Biphenyl Compounds; Cytochromes c; Glutathione; Liver; Liver Failure, Acute; Male; Membrane Potential, Mitochondrial; Methionine; Mice; Mitochondria, Liver; Mitochondrial Swelling; Necrosis	2008
Management of acute paracetamol poisoning in a tertiary care hospital. The Ceylon medical journal, 2008, Volume: 53, Issue:3 Topics: Acetaminophen; Acetylcysteine; Acute Disease; Analgesics, Non-Narcotic; Antidotes; Charcoal; Emetics; Evidence-Based Medicine; Female; Hospitals, Public; Humans; Male; Methionine; Poisoning; Sodium Bicarbonate; Sri Lanka; Time Factors; Treatment Outcome; Young Adult	2008
Cost of the paracetamol overdose epidemic. The Ceylon medical journal, 2010, Volume: 55, Issue:1 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug Overdose; Humans; Methionine; Sri Lanka; Suicide	2010
A mathematical modelling approach to assessing the reliability of biomarkers of glutathione metabolism. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jul-16, Volume: 46, Issue:4 Topics: Acetaminophen; Animals; Biomarkers; Computer Simulation; Glutathione; Humans; Inactivation, Metabolic; Liver; Methionine; Models, Biological; Oligopeptides; Pyrrolidonecarboxylic Acid; Reproducibility of Results; Systems Biology	2012
Effects of methionine containing paracetamol formulation on serum vitamins and trace elements in male rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2010, Nov-28, Volume: 25, Issue:2 Topics: Acetaminophen; Animals; Antioxidants; Male; Methionine; Rats; Rats, Wistar; Trace Elements; Vitamins	2010
A cost effectiveness analysis of the preferred antidotes for acute paracetamol poisoning patients in Sri Lanka. BMC clinical pharmacology, 2012, Feb-22, Volume: 12 Topics: Acetaminophen; Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; Decision Trees; Humans; Methionine; Sri Lanka; Time Factors	2012
Biochemical and histologic presentations of female Wistar rats administered with different doses of paracetamol/methionine. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2011, Dec-20, Volume: 26, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Female; Liver; Liver Function Tests; Methionine; Necrosis; Rats; Rats, Wistar	2011
Identification of early biomarkers during acetaminophen-induced hepatotoxicity by fourier transform infrared microspectroscopy. PloS one, 2012, Volume: 7, Issue:9 Topics: Acetaminophen; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Cholesterol Esters; Cytokines; DNA; Glycogen; Kinetics; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type II; Spectroscopy, Fourier Transform Infrared	2012
Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes. Antioxidants & redox signaling, 2014, Jun-01, Volume: 20, Issue:16 Topics: Acetaminophen; Acute Disease; Adenosylhomocysteinase; Animals; Chemical and Drug Induced Liver Injury; Cytoplasm; Galactosamine; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; Rats, Wistar; Tumor Cells, Cultured	2014
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice. Free radical biology & medicine, 2015, Volume: 89 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine	2015
Treatments for paracetamol poisoning. BMJ (Clinical research ed.), 2016, May-18, Volume: 353 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Drug Overdose; Female; Humans; Methionine; Time Factors; Young Adult	2016
l-Methionine and silymarin: A comparison of prophylactic protective capabilities in acetaminophen-induced injuries of the liver, kidney and cerebral cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85 Topics: Acetaminophen; Animals; Antioxidants; Anxiety; Behavior, Animal; Biomarkers; Brain Diseases; Cerebral Cortex; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Grooming; Kidney; Kidney Diseases; Liver; Memory, Short-Term; Methionine; Motor Activity; Organ Specificity; Oxidative Stress; Rats, Wistar; Silymarin; Spatial Memory; Time Factors; Weight Gain	2017
Determination of sofosbuvir with two co-administered drugs; paracetamol and DL-methionine by two chromatographic methods. Application to a pharmacokinetic study. Bioanalysis, 2019, Volume: 11, Issue:5 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antiviral Agents; Chromatography, Liquid; Drug Therapy, Combination; Female; Methionine; Rats; Sofosbuvir; Tandem Mass Spectrometry	2019
Dual-Mode Gradient HPLC and TLC Densitometry Methods for the Simultaneous Determination of Paracetamol and Methionine in the Presence of Paracetamol Impurities. Journal of AOAC International, 2021, Aug-20, Volume: 104, Issue:4 Topics: Acetaminophen; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; COVID-19; Densitometry; Humans; Methionine; Reproducibility of Results; SARS-CoV-2	2021
Peak shape enhancement using diethylamine in hydrophilic liquid interaction chromatography: Application in simultaneous determination of methionine and paracetamol. Journal of pharmaceutical and biomedical analysis, 2021, Sep-05, Volume: 203 Topics: Acetaminophen; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diethylamines; Hydrophobic and Hydrophilic Interactions; Methionine	2021