manganese and m 40403
manganese has been researched along with m 40403 in 54 studies
Research
Studies (54)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.70) | 18.2507 |
| 2000's | 40 (74.07) | 29.6817 |
| 2010's | 11 (20.37) | 24.3611 |
| 2020's | 1 (1.85) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Currie, MG; Cuzzocrea, S; Macarthur, H; Misko, TP; Riley, DP; Salvemini, D; Samouilov, A; Sikorski, JA; Wang, ZQ; Zweier, JL | 1 |
| Strauss, E | 1 |
| Macarthur, H; Misko, TP; Riley, DP; Salvemini, D; Westfall, TC | 1 |
| Riley, DP; Salvemini, D | 1 |
| Aston, K; Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D | 1 |
| Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D; Serraino, I | 1 |
| Aston, K; Naik, A; Rath, N; Riley, DP; Schall, OF; Slomczynska, U | 1 |
| Coppey, LJ; Davidson, EP; Dunlap, JA; Gellett, JS; Lund, DD; Salvemini, D; Yorek, MA | 1 |
| Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D | 1 |
| Caputi, AP; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Salvemini, D; Serraino, I | 1 |
| Cuzzocrea, S; Mannaioni, PF; Marzocca, C; Masini, E; Mazzon, E; Salvemini, D | 1 |
| Cuzzocrea, S; Riley, DP; Salvemini, D | 1 |
| Cuzzocrea, S; Salvemini, D | 1 |
| Britti, D; Caputi, A; Cuzzocrea, S; De Sarro, A; Di Paola, R; Dugo, L; Masini, E; Mazzon, E; Pierpaoli, S; Salvemini, D; Serraino, I | 1 |
| Cuzzocrea, S; Muscoli, C; Riley, DP; Salvemini, D | 1 |
| Bendtzen, K; Galdieri, M; Nicoletti, F; Papaccio, G; Pisanti, FA | 1 |
| Anastasio, N; Bao, J; Guidry, JA; Johnson, KM; McInnis, J; Salvemini, D; Wang, C; West, JB; Ye, Y | 1 |
| Ding, D; McFadden, SL; Salvemini, D; Salvi, RJ | 1 |
| Burton, D; Cuzzocrea, S; Macarthur, H; McGregor, JR; Petersen, R; Salvemini, D; Samlowski, WE | 1 |
| Cuzzocrea, S; Mannaioni, PF; Marzocca, C; Masini, E; Salvemini, D; Vannacci, A | 1 |
| Mier, JW; Sosman, JA | 1 |
| Busija, DW; Horiguchi, T; Payne, RM; Rajapakse, N; Shimizu, K | 1 |
| Griendling, KK; Weber, DS | 1 |
| Dusting, GJ; Guo, Y; Jiang, F; Salvemini, D | 1 |
| Arbiser, JL | 1 |
| Caputi, AP; Cuzzocrea, S; Di Paola, R; Dugo, L; Mazzon, E; Salvemini, D | 1 |
| Cuzzocrea, S; Galen, K; Ischiropoulos, H; Lightfoot, R; Masini, E; Mollace, V; Muscoli, C; Ndengele, M; Porreca, F; Salvemini, D; Wang, ZQ | 1 |
| Anastasio, N; Johnson, KM; Leday, A; Popov, V; Wang, C | 1 |
| Cuzzocrea, S; Dugo, L; Ianaro, A; Ndengele, M; Pisano, B; Salvemini, D | 1 |
| Berrino, L; Cuzzocrea, S; D'Amico, M; Di Filippo, C; Fabbroni, V; Giugliano, D; Marfella, R; Rossi, F; Scollo, G | 1 |
| Masini, E; Mollace, V; Muscoli, C; Ndengele, M; Salvemini, D; Wang, ZQ; Wheatley, J | 1 |
| Di Napoli, M; Papa, F | 1 |
| Doyle, TM; Matuschak, GM; Muscoli, C; Ndengele, MM; Salvemini, D; Wang, ZQ | 1 |
| Britti, D; Cuzzocrea, S; Dattola, F; De Majo, M; Di Paola, R; Genovese, T; Mazzon, E; Rotondo, F | 1 |
| Caputi, AP; Cuzzocrea, S; Genovese, T; Mazzon, E; Muià, C; Paola, RD; Salvemini, D | 1 |
| Bani, D; Comhair, SA; Erzurum, SC; Mannaioni, PF; Masini, E; Muscoli, C; Pierpaoli, S; Salvemini, D; Vannacci, A; Xu, W | 1 |
| Caputi, AP; Cuzzocrea, S; di Paola, R; Genovese, T; Mazzon, E; Muià, C; Salvemini, D | 1 |
| Durazo, A; Gralla, EB; Imlay, JA; Kingsley, C; Munroe, W; Srinivasan, C; Valentine, JS | 1 |
| Kondapaneni, M; Laubach, VE; McGregor, JR; Salvemini, D; Samlowski, WE | 1 |
| Fey, EG; Murphy, CK; Rothstein, D; Sonis, ST; Watkins, BA; Wong, V | 1 |
| Bernhardt, F; Cordi, A; Gaertner, R; Jaulmes, A; Lockhart, BP; Rolland-Valognes, G; Rupin, A; Sansilvestri-Morel, P; Verbeuren, TJ; Wierzbicki, M | 1 |
| Aschner, JL; Aschner, M; Dennis, KE; Fike, CD; Kaplowitz, MR; Milatovic, D; Schmidt, JW; Zhang, Y | 1 |
| Brown, SA; Chu, Y; Glass, J; Tapp, AA; Thompson, JS | 1 |
| Liu, F; Paule, MG; Slikker, W; Wang, C; Zhang, X | 1 |
| Kondapaneni, M; Laubach, VE; McGregor, JR; Salvemini, D; Samlowski, WE; Tharkar, S | 1 |
| Buzadzic, B; Filipovic, MR; Garalejic, E; Golic, I; Ivanovic-Burmazovic, I; Jankovic, A; Korac, A; Korac, B; Macanovic, B; Markelic, M; Otasevic, V; Stancic, A; Velickovic, K; Vucetic, M | 1 |
| Amaral, A; Ramalho-Santos, J | 1 |
| Anderson, RF; Brooker, S; Cochemé, HM; James, AM; Kelso, GF; Logan, A; Maroz, A; Murphy, MP; Peskin, AV; Porteous, CM; Prime, TA; Ross, MF; Smith, RA; Winterbourn, CC | 1 |
| Aitken, RJ | 1 |
| Korac, B | 1 |
| Beltramini, M; Bisaglia, M; Bubacco, L; Casella, L; Ferrari, E; Filograna, R; Godena, VK; Sanchez-Martinez, A; Whitworth, AJ | 1 |
| Buzadzic, B; Filipovic, M; Ivanovic-Burmazovic, I; Jankovic, A; Korac, A; Korac, B; Masovic, S; Otasevic, V; Stancic, A | 1 |
| Alam, SM; Beltramini, M; Biosa, A; Bisaglia, M; Bubacco, L; Filograna, R; Sanchez-Martinez, A; Terriente-Felix, A; Whitworth, AJ | 1 |
| Batinic-Haberle, I; Delsuc, N; Layani, S; Mathieu, E; Policar, C; Quévrain, E; Seksik, P; Thauvin, M; Vincent, A; Vriz, S | 1 |
Reviews
6 review(s) available for manganese and m 40403
| Article | Year |
|---|---|
SOD mimetics are coming of age.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Humans; Manganese; Metalloporphyrins; Organometallic Compounds; Superoxide Dismutase; Superoxides | 2002 |
Superoxide, superoxide dismutase and ischemic injury.
Topics: Animals; Free Radical Scavengers; Humans; Manganese; Organometallic Compounds; Reperfusion Injury; Superoxide Dismutase; Superoxides | 2002 |
Superoxide dismutase mimetics.
Topics: Anti-Inflammatory Agents; Free Radical Scavengers; Humans; Inflammation; Manganese; Molecular Structure; Organometallic Compounds; Superoxide Dismutase; Superoxides | 2002 |
The yin/yang of superoxide dismutase mimetics: potential cardiovascular therapies?
Topics: Animals; Cardiovascular Diseases; Humans; Manganese; Molecular Mimicry; Organometallic Compounds; Superoxide Dismutase | 2003 |
M-40403 Metaphore Pharmaceuticals.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drugs, Investigational; Free Radical Scavengers; Humans; Manganese; Organometallic Compounds; Technology, Pharmaceutical | 2005 |
Anesthetic-induced oxidative stress and potential protection.
Topics: Anesthetics, Dissociative; Antioxidants; Apoptosis; Ketamine; Manganese; Microscopy, Electron; Models, Biological; Neurons; Organometallic Compounds; Oxidative Stress; Receptors, N-Methyl-D-Aspartate | 2010 |
Other Studies
48 other study(ies) available for manganese and m 40403
| Article | Year |
|---|---|
A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytoprotection; Dinoprostone; Dose-Response Relationship, Drug; Drug Design; Drug Stability; Inflammation; Interleukin-1; L-Lactate Dehydrogenase; Male; Manganese; Molecular Mimicry; Neutrophils; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splanchnic Circulation; Superoxide Dismutase; Superoxides; Time Factors; Tumor Necrosis Factor-alpha | 1999 |
Possible new anti-inflammatory agent.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Computer Simulation; Drug Design; Inflammation; Intestines; Manganese; Molecular Mimicry; Organometallic Compounds; Rats; Reperfusion Injury; Superoxide Dismutase; Superoxides | 1999 |
Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock.
Topics: Adrenochrome; Animals; Blood Pressure; Catecholamines; Disease Models, Animal; Dose-Response Relationship, Drug; Epinephrine; Hypotension; Kinetics; Lipopolysaccharides; Male; Manganese; Norepinephrine; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Shock, Septic; Superoxide Dismutase; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Nonpeptidyl mimetics of superoxide dismutase in clinical therapies for diseases.
Topics: Antioxidants; Disease; Hydrogen-Ion Concentration; Iron; Manganese; Molecular Mimicry; Organometallic Compounds; Oxygen; Peroxides; Signal Transduction; Superoxide Dismutase; Superoxides | 2000 |
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterial Occlusive Diseases; Catalysis; Cytokines; Fluorescent Antibody Technique; Ileum; Leukocyte Count; Male; Malondialdehyde; Manganese; Nitrates; Nitrites; Organometallic Compounds; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splanchnic Circulation; Superoxide Dismutase; Superoxides; Tyrosine | 2001 |
Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; DNA Damage; Intercellular Adhesion Molecule-1; Macrophages; Male; Manganese; Nitrates; Organometallic Compounds; P-Selectin; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Superoxides | 2001 |
Computer-aided design (CAD) of Mn(II) complexes: superoxide dismutase mimetics with catalytic activity exceeding the native enzyme.
Topics: Catalysis; Computer-Aided Design; Crystallography, X-Ray; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Manganese; Models, Molecular; Molecular Conformation; Molecular Mimicry; Molecular Structure; Organometallic Compounds; Stereoisomerism; Superoxide Dismutase | 2001 |
Effect of M40403 treatment of diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Vessels; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Fructose; Inositol; Male; Manganese; Neural Conduction; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Sorbitol; Superoxides; Thiobarbituric Acid Reactive Substances; Triglycerides; Tyrosine; Vasodilation; Vasodilator Agents | 2001 |
Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis.
Topics: Animals; Body Weight; Colitis; Colon; Cytokines; Enzyme Activation; Free Radical Scavengers; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Manganese; Organometallic Compounds; P-Selectin; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Survival Analysis; Time Factors; Tyrosine | 2001 |
Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Arthritis, Experimental; Arthritis, Rheumatoid; Arthrography; Collagen; Collagen Type XI; Disease Models, Animal; Interleukin-1; Joints; Male; Manganese; Molecular Weight; Organometallic Compounds; Proteins; Rats; Rats, Inbred Lew; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine; Weight Gain | 2001 |
Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo.
Topics: Animals; Cardiotonic Agents; Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Manganese; Molecular Mimicry; Myocardial Ischemia; Myocardial Reperfusion Injury; Organometallic Compounds; P-Selectin; Peroxidase; Rats; Rats, Wistar; Superoxide Dismutase; Tyrosine | 2002 |
A role for superoxide in gentamicin-mediated nephropathy in rats.
Topics: Animals; Anti-Bacterial Agents; Enzyme Activation; Free Radical Scavengers; Gentamicins; Kidney; Lipid Peroxidation; Male; Manganese; Molecular Mimicry; Neutrophil Infiltration; Organometallic Compounds; Oxidants; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Renal Circulation; Renal Insufficiency; Superoxide Dismutase; Superoxides; Tyrosine | 2002 |
An imidazoline compound completely counteracts interleukin-1[beta] toxic effects to rat pancreatic islet [beta] cells.
Topics: Animals; Imidazoles; Indoles; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Manganese; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organometallic Compounds; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase | 2002 |
Blockade of phencyclidine-induced cortical apoptosis and deficits in prepulse inhibition by M40403, a superoxide dismutase mimetic.
Topics: Acoustic Stimulation; Animals; Apoptosis; Blotting, Western; Cerebral Cortex; DNA Fragmentation; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; In Situ Nick-End Labeling; Manganese; Molecular Mimicry; Neurotoxicity Syndromes; Organometallic Compounds; Phencyclidine; Pregnancy; Rats; Rats, Sprague-Dawley; Reflex, Startle; Superoxide Dismutase | 2003 |
M40403, a superoxide dismutase mimetic, protects cochlear hair cells from gentamicin, but not cisplatin toxicity.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Cisplatin; Cochlea; Gentamicins; Hair Cells, Auditory; Manganese; Mice; Mice, Inbred C57BL; Organometallic Compounds | 2003 |
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects.
Topics: Animals; Antineoplastic Agents; Catecholamines; Dose-Response Relationship, Drug; Female; Humans; Hypotension; Interleukin-2; Kidney Neoplasms; Killer Cells, Natural; Lymphocyte Activation; Macrophages; Manganese; Melanoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Mimicry; Molecular Structure; Organometallic Compounds; Superoxide Dismutase; Survival Rate | 2003 |
Effects of the SOD mimetic, M40403, on prostaglandin production in an in vivo model of ischemia and reperfusion in rat heart.
Topics: Animals; Male; Manganese; Myocardial Reperfusion Injury; Myocardium; Organometallic Compounds; Peroxidase; Prostaglandins; Rats; Rats, Wistar; Superoxide Dismutase | 2003 |
Biological drug duo delivers one-two tumor punch.
Topics: Animals; Antineoplastic Agents; Humans; Interleukin-2; Kidney Neoplasms; Manganese; Melanoma; Mice; Organometallic Compounds; Superoxides; Survival Rate | 2003 |
Neuroprotection against hypoxia-ischemia in neonatal rat brain by novel superoxide dismutase mimetics.
Topics: Animals; Animals, Newborn; Brain; Hypoxia-Ischemia, Brain; Manganese; Neuroprotective Agents; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2003 |
Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)-deficient mice.
Topics: Animals; Aorta, Thoracic; Apolipoproteins E; Dose-Response Relationship, Drug; Endothelial Cells; Free Radical Scavengers; In Vitro Techniques; Male; Manganese; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Muscle, Smooth, Vascular; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 2003 |
Role of manganese superoxide dismutase in cancer.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Interleukin-2; Manganese; Melanoma; Molecular Mimicry; Organometallic Compounds; Reactive Oxygen Species; Superoxide Dismutase | 2003 |
Superoxide: a key player in hypertension.
Topics: Animals; Aorta; Blood Pressure; Culture Techniques; Hypertension; Kinetics; Manganese; Organometallic Compounds; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Tyrosine; Vasodilation | 2004 |
A newly identified role for superoxide in inflammatory pain.
Topics: Animals; Carrageenan; Edema; Hyperalgesia; Male; Manganese; Organometallic Compounds; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Superoxide Dismutase; Superoxides | 2004 |
Blockade of N-methyl-D-aspartate receptors by phencyclidine causes the loss of corticostriatal neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Count; Cerebral Cortex; Corpus Striatum; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Immunohistochemistry; In Situ Nick-End Labeling; Male; Manganese; Microscopy, Electron; Neural Cell Adhesion Molecule L1; Neurons; Organ Culture Techniques; Organometallic Compounds; Phencyclidine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sialic Acids; Superoxide Dismutase; Synaptophysin; Synaptosomes | 2004 |
Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation.
Topics: Animals; Carrageenan; I-kappa B Proteins; Inflammation; Interleukin-1; Lung; Male; Manganese; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Organometallic Compounds; Pleurisy; Random Allocation; Signal Transduction; Superoxide Dismutase; Superoxides; Tumor Necrosis Factor-alpha | 2004 |
M40403 prevents myocardial injury induced by acute hyperglycaemia in perfused rat heart.
Topics: Animals; Antioxidants; Cells, Cultured; DNA Damage; Endothelial Cells; Endothelium, Vascular; Glucose; Heart; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Manganese; Mitochondria; Myocardial Reperfusion Injury; Myocardium; Organometallic Compounds; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tyrosine | 2004 |
Superoxide-mediated nitration of spinal manganese superoxide dismutase: a novel pathway in N-methyl-D-aspartate-mediated hyperalgesia.
Topics: Animals; Excitatory Amino Acid Agonists; Hyperalgesia; Male; Manganese; N-Methylaspartate; Nitrogen; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Superoxide Dismutase; Superoxides | 2004 |
Superoxide potentiates NF-kappaB activation and modulates endotoxin-induced cytokine production in alveolar macrophages.
Topics: Animals; Blotting, Western; Cell Nucleus; Coloring Agents; Cytokines; Cytoplasm; Endotoxins; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Escherichia coli; I-kappa B Proteins; Immunoblotting; Inflammation; Interleukin-1; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages; Macrophages, Alveolar; Manganese; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Organometallic Compounds; Oxidation-Reduction; Oxygen; Phenanthridines; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Superoxides; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2005 |
Reduced development of experimental periodontitis by treatment with M40403, a superoxide dismutase mimetic.
Topics: Alveolar Bone Loss; Animals; Capillary Permeability; Ligation; Lipid Peroxidation; Male; Manganese; Neutrophil Infiltration; Organometallic Compounds; Periodontitis; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tyrosine | 2005 |
Effects of combination M40403 and dexamethasone therapy on joint disease in a rat model of collagen-induced arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Bone and Bones; Collagen; Dexamethasone; Drug Therapy, Combination; Male; Manganese; Models, Animal; Organometallic Compounds; Rats; Rats, Inbred Lew; Superoxide Dismutase | 2005 |
Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Allergens; Animals; Apoptosis; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Deoxyguanosine; Guinea Pigs; Lung; Male; Malondialdehyde; Manganese; Organometallic Compounds; Ovalbumin; Peroxidase; Prostaglandin D2; Superoxide Dismutase | 2005 |
Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance.
Topics: Animals; Antioxidants; Antirheumatic Agents; Arthritis, Experimental; Cytokines; Drug Synergism; Drug Therapy, Combination; Male; Manganese; Methotrexate; Molecular Mimicry; Organometallic Compounds; Rats; Rats, Inbred Lew; Superoxide Dismutase; Weight Gain | 2005 |
Only one of a wide assortment of manganese-containing SOD mimicking compounds rescues the slow aerobic growth phenotypes of both Escherichia coli and Saccharomyces cerevisiae strains lacking superoxide dismutase enzymes.
Topics: Aerobiosis; Escherichia coli; Manganese; Manganese Compounds; Metalloporphyrins; Molecular Mimicry; Molecular Structure; Mutation; Organometallic Compounds; Porphyrins; Saccharomyces cerevisiae; Salicylates; Superoxide Dismutase | 2007 |
Inducible nitric oxide synthase (iNOS) is not required for IL-2-induced hypotension and vascular leak syndrome in mice.
Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Genetic Predisposition to Disease; Hypotension; Interferon-gamma; Interleukin-2; Lysine; Manganese; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Organometallic Compounds | 2008 |
Efficacy of superoxide dismutase mimetic M40403 in attenuating radiation-induced oral mucositis in hamsters.
Topics: Animals; Antioxidants; Cricetinae; Disease Progression; Free Radicals; Male; Manganese; Mesocricetus; Models, Chemical; Neoplasms; Organometallic Compounds; Oxygen; Radiation Injuries; Radiotherapy; Stomatitis; Superoxide Dismutase | 2008 |
Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells.
Topics: Acetylcysteine; Benzopyrans; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Humans; Manganese; MAP Kinase Signaling System; NADPH Oxidase 4; NADPH Oxidases; Onium Compounds; Organometallic Compounds; p38 Mitogen-Activated Protein Kinases; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering | 2009 |
NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets.
Topics: Animals; Animals, Newborn; Antioxidants; Catalase; F2-Isoprostanes; Hypertension, Pulmonary; Hypoxia; Immunoblotting; Luminescence; Manganese; NADPH Oxidase 1; NADPH Oxidases; Organometallic Compounds; Phosphoproteins; Pulmonary Artery; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Swine; Vascular Resistance | 2009 |
The manganese superoxide dismutase mimetic, M40403, protects adult mice from lethal total body irradiation.
Topics: Animals; Antioxidants; Apoptosis; Biomimetic Materials; Dose-Response Relationship, Radiation; Hematopoietic System; Lymphoid Tissue; Male; Manganese; Mice; Mice, Inbred BALB C; Organometallic Compounds; Oxidative Stress; Radiation-Protective Agents; Superoxide Dismutase; Survival Rate; Whole-Body Irradiation | 2010 |
Endothelial nitric oxide synthase is a key mediator of interleukin-2-induced hypotension and vascular leak syndrome.
Topics: Animals; Blood Pressure; Capillary Leak Syndrome; Carcinoma, Renal Cell; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; Hypotension; Interleukin-2; Manganese; Melanoma; Methylene Blue; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organometallic Compounds; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase; Superoxides | 2011 |
Is manganese (II) pentaazamacrocyclic superoxide dismutase mimic beneficial for human sperm mitochondria function and motility?
Topics: Antioxidants; Base Sequence; DNA Primers; Humans; Male; Manganese; Mitochondria; Molecular Mimicry; Organometallic Compounds; Real-Time Polymerase Chain Reaction; Sperm Motility; Spermatozoa; Superoxide Dismutase | 2013 |
The male gamete is not a somatic cell--the possible meaning of varying sperm RNA levels.
Topics: Humans; Male; Manganese; Mitochondria; Molecular Mimicry; Organometallic Compounds; Sperm Motility; Spermatozoa; Superoxide Dismutase | 2013 |
A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic.
Topics: Aconitate Hydratase; Animals; Ascorbic Acid; Biomimetic Materials; Catalysis; Crystallography, X-Ray; Kinetics; Macrocyclic Compounds; Manganese; Microsomes, Liver; Mitochondria; Molecular Conformation; Organometallic Compounds; Oxidation-Reduction; Pulse Radiolysis; Rats; Superoxide Dismutase; Superoxides | 2012 |
Can spermatozoa respond to changes in their redox status with the selective activation of gene transcription?
Topics: Humans; Male; Manganese; Mitochondria; Molecular Mimicry; Organometallic Compounds; Sperm Motility; Spermatozoa; Superoxide Dismutase | 2013 |
Author response.
Topics: Humans; Male; Manganese; Mitochondria; Molecular Mimicry; Organometallic Compounds; Sperm Motility; Spermatozoa; Superoxide Dismutase | 2013 |
Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE.
Topics: Animals; Biomimetic Materials; Cell Line, Tumor; Drosophila melanogaster; Humans; Manganese; Models, Biological; Organometallic Compounds; Oxidative Stress; Paraquat; Parkinson Disease; Superoxide Dismutase | 2016 |
Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l-arginine and SOD mimic.
Topics: AMP-Activated Protein Kinases; Animals; Arginine; Diabetes Mellitus, Experimental; Energy Metabolism; Glucose Transporter Type 4; GTP Phosphohydrolases; Manganese; Mitochondria; Muscle, Skeletal; Nitric Oxide; Organometallic Compounds; Oxidative Phosphorylation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Superoxides | 2017 |
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss.
Topics: Blotting, Western; HEK293 Cells; HeLa Cells; Humans; Manganese; Organometallic Compounds; Oxidative Stress; Parkinson Disease; Protein Kinases; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitin-Protein Ligases | 2018 |
Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models.
Topics: Animals; Antioxidants; Catalase; Cell Line; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Manganese; Metalloporphyrins; Molecular Mimicry; Organometallic Compounds; Oxidation-Reduction; Oxidative Stress; Porphyrins; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2021 |