Page last updated: 2024-09-03

ly 255283 and sc 41930

ly 255283 has been researched along with sc 41930 in 5 studies

Compound Research Comparison

Studies
(ly 255283)
Trials
(ly 255283)
Recent Studies (post-2010)
(ly 255283)
Studies
(sc 41930)
Trials
(sc 41930)
Recent Studies (post-2010) (sc 41930)
540155400

Protein Interaction Comparison

ProteinTaxonomyly 255283 (IC50)sc 41930 (IC50)
Leukotriene B4 receptor 1Homo sapiens (human)0.6716
Leukotriene B4 receptor 2Homo sapiens (human)2.045

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bach, NJ; Baker, SR; Baldwin, RF; Borromeo, PS; Cockerham, SL; Fleisch, JH; Floreancig, P; Froelich, LL; Jackson, WT; Sawyer, JS1
Brooks, CD; Summers, JB1
Grisham, MB; Keenan, CM; Vaananen, PM; Wallace, JL1
Herron, DK; Marder, P; Schultz, RM; Sofia, MJ; Spaethe, SM2

Reviews

1 review(s) available for ly 255283 and sc 41930

ArticleYear
Modulators of leukotriene biosynthesis and receptor activation.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene

1996

Other Studies

4 other study(ies) available for ly 255283 and sc 41930

ArticleYear
Synthetic and structure/activity studies on acid-substituted 2-arylphenols: discovery of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- hydroxyphenoxy]-propoxy]phenoxy]benzoic acid, a high-affinity leukotriene B4 receptor antagonist.
    Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22

    Topics: Airway Obstruction; Animals; Benzoates; Guinea Pigs; Humans; Leukotriene B4; Lung; Neutrophils; Phenols; Receptors, Leukotriene B4; Structure-Activity Relationship; Tetrazoles

1995
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
    Inflammation, 1992, Volume: 16, Issue:3

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrans; Carrier Proteins; Free Radical Scavengers; Gastric Mucosa; Hydroxyurea; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Proteins; Organic Chemicals; Permeability; Phenylcarbamates; Propionates; Quinolines; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Leukotriene B4; Single-Blind Method; Stomach Ulcer; Sulfonamides; Tetrazoles; Tosyl Compounds

1992
Flow cytometric evaluation of the effects of leukotriene B4 receptor antagonists (LY255283 and SC-41930) on calcium mobilization and integrin expression of activated human neutrophils.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 46, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Integrins; Leukotriene B4; Neutrophils; Receptors, Immunologic; Receptors, Leukotriene B4; Tetrazoles; Up-Regulation

1992
Effects of two leukotriene B4 (LTB4) receptor antagonists (LY255283 and SC-41930) on LTB4-induced human neutrophil adhesion and superoxide production.
    Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 43, Issue:4

    Topics: Adult; Benzopyrans; Cell Adhesion; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Receptors, Immunologic; Receptors, Leukotriene B4; Superoxides; Tetrazoles

1991