lomustine and guanine

lomustine has been researched along with guanine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's11 (64.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dolan, ME; Mitchell, RB; Moschel, RC; Mummert, C; Pegg, AE1
Dolan, ME; Mitchell, RB; Moschel, RC1
Said, B; Shank, RC1
Carter, CA; Habraken, Y; Ludlum, DB; Sekiguchi, M1
Carter, CA; Habraken, Y; Kirk, MC; Ludlum, DB1
Dolan, ME; Moschel, RC; Pegg, AE1
Carter, CA; Habraken, Y; Kirk, MC; Ludlum, DB; Riordan, JM1
Anderson, SP; Briscoe, WT; May, HE1
Dolan, ME; English, HF; Larkin, GL; Pegg, AE1
Clyde, C; Dolan, ME; Erickson, LC; Hora, NK; Norbeck, L; Pegg, AE1
Dolan, ME; Erickson, LC; Hora, NK; Pegg, AE1
Gibson, NW; Hartley, JA; Kohn, KW; Mattes, WB1
Carter, CA; Habraken, Y; Ludlum, DB1
Corsico, CD; Dolan, ME; Pegg, AE1
Baer, JC; Freeman, AA; Margison, GP; Newlands, ES; Rafferty, JA; Watson, AJ1
Kohda, K; Terashima, I1
Aquilina, G; Bignami, M; Ceccotti, S; Hampson, R; Martinelli, S1

Other Studies

17 other study(ies) available for lomustine and guanine

ArticleYear
Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
    Cancer research, 1991, Jul-01, Volume: 51, Issue:13

    Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Cell Survival; Cisplatin; Cyclophosphamide; DNA; DNA Damage; Drug Synergism; Guanine; Humans; In Vitro Techniques; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Tumor Cells, Cultured

1991
Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation.
    Cancer research, 1992, Mar-01, Volume: 52, Issue:5

    Topics: Animals; Carmustine; Colonic Neoplasms; DNA; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Female; Guanine; Humans; Lomustine; Mice; Mice, Nude; Transplantation, Heterologous; Tumor Cells, Cultured

1992
Nearest neighbor effects on carcinogen binding to guanine runs in DNA.
    Nucleic acids research, 1991, Mar-25, Volume: 19, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Autoradiography; Base Sequence; Benzo(a)pyrene; Binding, Competitive; Carcinogens; DNA; Electrophoresis, Agar Gel; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Lomustine; Methylnitrosourea; Molecular Sequence Data; Photochemistry; Plasmids

1991
Release of N2,3-ethanoguanine from haloethylnitrosourea-treated DNA by Escherichia coli 3-methyladenine DNA glycosylase II.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Topics: Bacterial Proteins; Carbon Radioisotopes; DNA; DNA Glycosylases; Escherichia coli; Guanine; Kinetics; Lomustine; N-Glycosyl Hydrolases; Substrate Specificity

1991
Release of 7-alkylguanines from N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea-modified DNA by 3-methyladenine DNA glycosylase II.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: Alkylation; Carbon Radioisotopes; DNA; DNA Glycosylases; Escherichia coli; Guanine; Kinetics; Lomustine; N-Glycosyl Hydrolases; Spectrophotometry, Ultraviolet

1991
Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:14

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Drug Synergism; Guanine; Humans; Kidney; Kinetics; Liver; Lomustine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Formation of N2,3-ethanoguanine in DNA after in vitro treatment with the therapeutic agent, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea.
    Carcinogenesis, 1990, Volume: 11, Issue:2

    Topics: Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine

1990
Base sequence specificity of three 2-chloroethylnitrosoureas.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Alkylation; Base Sequence; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine; Nitrosourea Compounds; Semustine; Structure-Activity Relationship

1990
Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; Mice; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Time Factors; Transplantation, Heterologous

1989
Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
    Carcinogenesis, 1989, Volume: 10, Issue:9

    Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Line; Cricetinae; Cricetulus; Female; Guanine; Kinetics; Lomustine; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mitoguazone; O(6)-Methylguanine-DNA Methyltransferase; Ovary; Transfection

1989
Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
    Cancer research, 1988, Jul-01, Volume: 48, Issue:13

    Topics: Cell Division; Cell Survival; Cross-Linking Reagents; DNA Damage; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1988
DNA sequence selectivity of guanine-N7 alkylation by three antitumor chloroethylating agents.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 2

    Topics: Alkylating Agents; Alkylation; Antineoplastic Agents; Autoradiography; Base Sequence; DNA; Ethylnitrosourea; Guanine; Hydrogen-Ion Concentration; Lomustine; Mesylates; Nitrogen Mustard Compounds

1986
Release of 7-alkylguanines from haloethylnitrosourea-treated DNA by E. coli 3-methyladenine-DNA glycosylase II.
    Biochemical and biophysical research communications, 1988, Sep-30, Volume: 155, Issue:3

    Topics: Chromatography, High Pressure Liquid; DNA; DNA Glycosylases; Escherichia coli; Guanine; Lomustine; N-Glycosyl Hydrolases

1988
Exposure of HeLa cells to 0(6)-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents.
    Biochemical and biophysical research communications, 1985, Oct-15, Volume: 132, Issue:1

    Topics: Cell Division; DNA Repair; Guanine; HeLa Cells; Humans; Lomustine; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Time Factors

1985
Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.
    British journal of cancer, 1993, Volume: 67, Issue:6

    Topics: Antineoplastic Agents; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Guanine; Humans; Lomustine; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Tumor Cells, Cultured

1993
Cytotoxicity of fluoroethylating agents is potentiated by O6-benzylguanine.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Cell Survival; Drug Synergism; Guanine; HeLa Cells; Humans; Iodoacetamide; Lomustine; Nimustine

1996
N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells.
    Cancer research, 1998, Jan-01, Volume: 58, Issue:1

    Topics: Animals; Antineoplastic Agents; CHO Cells; Cricetinae; DNA Repair; Guanine; HeLa Cells; Humans; Lomustine; Methylation; O(6)-Methylguanine-DNA Methyltransferase

1998