lomustine and guanine
lomustine has been researched along with guanine in 17 studies
Research
Studies (17)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 11 (64.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Dolan, ME; Mitchell, RB; Moschel, RC; Mummert, C; Pegg, AE | 1 |
| Dolan, ME; Mitchell, RB; Moschel, RC | 1 |
| Said, B; Shank, RC | 1 |
| Carter, CA; Habraken, Y; Ludlum, DB; Sekiguchi, M | 1 |
| Carter, CA; Habraken, Y; Kirk, MC; Ludlum, DB | 1 |
| Dolan, ME; Moschel, RC; Pegg, AE | 1 |
| Carter, CA; Habraken, Y; Kirk, MC; Ludlum, DB; Riordan, JM | 1 |
| Anderson, SP; Briscoe, WT; May, HE | 1 |
| Dolan, ME; English, HF; Larkin, GL; Pegg, AE | 1 |
| Clyde, C; Dolan, ME; Erickson, LC; Hora, NK; Norbeck, L; Pegg, AE | 1 |
| Dolan, ME; Erickson, LC; Hora, NK; Pegg, AE | 1 |
| Gibson, NW; Hartley, JA; Kohn, KW; Mattes, WB | 1 |
| Carter, CA; Habraken, Y; Ludlum, DB | 1 |
| Corsico, CD; Dolan, ME; Pegg, AE | 1 |
| Baer, JC; Freeman, AA; Margison, GP; Newlands, ES; Rafferty, JA; Watson, AJ | 1 |
| Kohda, K; Terashima, I | 1 |
| Aquilina, G; Bignami, M; Ceccotti, S; Hampson, R; Martinelli, S | 1 |
Other Studies
17 other study(ies) available for lomustine and guanine
| Article | Year |
|---|---|
Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Cell Survival; Cisplatin; Cyclophosphamide; DNA; DNA Damage; Drug Synergism; Guanine; Humans; In Vitro Techniques; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Tumor Cells, Cultured | 1991 |
Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation.
Topics: Animals; Carmustine; Colonic Neoplasms; DNA; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Female; Guanine; Humans; Lomustine; Mice; Mice, Nude; Transplantation, Heterologous; Tumor Cells, Cultured | 1992 |
Nearest neighbor effects on carcinogen binding to guanine runs in DNA.
Topics: Aflatoxin B1; Aflatoxins; Autoradiography; Base Sequence; Benzo(a)pyrene; Binding, Competitive; Carcinogens; DNA; Electrophoresis, Agar Gel; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Lomustine; Methylnitrosourea; Molecular Sequence Data; Photochemistry; Plasmids | 1991 |
Release of N2,3-ethanoguanine from haloethylnitrosourea-treated DNA by Escherichia coli 3-methyladenine DNA glycosylase II.
Topics: Bacterial Proteins; Carbon Radioisotopes; DNA; DNA Glycosylases; Escherichia coli; Guanine; Kinetics; Lomustine; N-Glycosyl Hydrolases; Substrate Specificity | 1991 |
Release of 7-alkylguanines from N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea-modified DNA by 3-methyladenine DNA glycosylase II.
Topics: Alkylation; Carbon Radioisotopes; DNA; DNA Glycosylases; Escherichia coli; Guanine; Kinetics; Lomustine; N-Glycosyl Hydrolases; Spectrophotometry, Ultraviolet | 1991 |
Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Drug Synergism; Guanine; Humans; Kidney; Kinetics; Liver; Lomustine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Formation of N2,3-ethanoguanine in DNA after in vitro treatment with the therapeutic agent, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea.
Topics: Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine | 1990 |
Base sequence specificity of three 2-chloroethylnitrosoureas.
Topics: Alkylation; Base Sequence; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine; Nitrosourea Compounds; Semustine; Structure-Activity Relationship | 1990 |
Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; Mice; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Time Factors; Transplantation, Heterologous | 1989 |
Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Line; Cricetinae; Cricetulus; Female; Guanine; Kinetics; Lomustine; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mitoguazone; O(6)-Methylguanine-DNA Methyltransferase; Ovary; Transfection | 1989 |
Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
Topics: Cell Division; Cell Survival; Cross-Linking Reagents; DNA Damage; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured | 1988 |
DNA sequence selectivity of guanine-N7 alkylation by three antitumor chloroethylating agents.
Topics: Alkylating Agents; Alkylation; Antineoplastic Agents; Autoradiography; Base Sequence; DNA; Ethylnitrosourea; Guanine; Hydrogen-Ion Concentration; Lomustine; Mesylates; Nitrogen Mustard Compounds | 1986 |
Release of 7-alkylguanines from haloethylnitrosourea-treated DNA by E. coli 3-methyladenine-DNA glycosylase II.
Topics: Chromatography, High Pressure Liquid; DNA; DNA Glycosylases; Escherichia coli; Guanine; Lomustine; N-Glycosyl Hydrolases | 1988 |
Exposure of HeLa cells to 0(6)-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents.
Topics: Cell Division; DNA Repair; Guanine; HeLa Cells; Humans; Lomustine; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Time Factors | 1985 |
Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.
Topics: Antineoplastic Agents; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Guanine; Humans; Lomustine; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Tumor Cells, Cultured | 1993 |
Cytotoxicity of fluoroethylating agents is potentiated by O6-benzylguanine.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Cell Survival; Drug Synergism; Guanine; HeLa Cells; Humans; Iodoacetamide; Lomustine; Nimustine | 1996 |
N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells.
Topics: Animals; Antineoplastic Agents; CHO Cells; Cricetinae; DNA Repair; Guanine; HeLa Cells; Humans; Lomustine; Methylation; O(6)-Methylguanine-DNA Methyltransferase | 1998 |