lignans and harman

lignans has been researched along with harman* in 2 studies

Other Studies

2 other study(ies) available for lignans and harman

ArticleYear
Simiranes A and B: erythroxylanes diterpenes and other compounds from Simira eliezeriana (Rubiaceae).
    Natural product research, 2011, Volume: 25, Issue:18

    The first phytochemical study of Simira eliezeriana Peixoto (Rubiaceae) allowed the isolation and structural determination of two new diterpenes named simirane A [(5R,6R,8R,9R,10S,11S,13S)-6β,11β-dihydroxy-2,4(18),15-erythroxylatrien-1-one] (1) and simirane B [(5S,8R,9R,10S,11S,13S)-11β-hydroxy-2,4(18),15-erythroxylatrien-1-one] (2), together with seven known compounds: sitosterol (3), stigmasterol (4), campesterol (5), coniferaldehyde (6), vanillin (7), pinoresinol (8) and harman (9) from the bark of the plant. The structures of the compounds were established on the basis of spectroscopic methods, including 1-D and 2-D NMR, HRESI-MS and CD analysis and comparisons with available literature data of known compounds.

    Topics: Acrolein; Benzaldehydes; Cholesterol; Diterpenes; Ethanol; Furans; Harmine; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Phytosterols; Plant Bark; Plant Extracts; Rubiaceae; Sitosterols

2011
Anti-AIDS agents. 46. Anti-HIV activity of harman, an anti-HIV principle from Symplocos setchuensis, and its derivatives.
    Journal of natural products, 2001, Volume: 64, Issue:7

    Matairesinol (1) and harman (5), identified from Symplocos setchuensis, were found to inhibit HIV replication in H9 lymphocyte cells. Anti-HIV evaluation of 28 derivatives of 5 revealed that compound 19 showed potent activity with EC(50) and therapeutic index values of 0.037 microM and 210, respectively.

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Furans; Harmine; Humans; Lignans; Lymphocytes; Molecular Structure; Plants, Medicinal; Structure-Activity Relationship

2001