lignans and furan
lignans has been researched along with furan* in 5 studies
Reviews
1 review(s) available for lignans and furan
| Article | Year |
|---|---|
Synthetic studies on optically active furofuran and diarylbutane lignans.
Lignans are a large class of naturally occurring secondary metabolites which are widely spread within the plant kingdom. Their diverse structures and variety of biological activities have fascinated organic chemists. For synthesizing optically active lignans, we have developed the novel asymmetric dimerization of cinnamic acid derivatives, and applied it to the enantioselective syntheses of furofuran lignans (yangambin, sesamin, eudesmin, caruilignan A) and diarylbutane lignans (sauriols A and B). This review summarizes the methodology of our asymmetric dimerization of cinnamic acid derivatives, and efficient total syntheses of furofuran and diarylbutane lignans reported by our and other groups. Topics: Butanes; Dimerization; Furans; Lignans; Optical Phenomena; Stereoisomerism | 2018 |
Other Studies
4 other study(ies) available for lignans and furan
| Article | Year |
|---|---|
Isolation and Identification of Lignans and Other Phenolic Constituents from the Stem Bark of
A dibenzylbutane-type lignan ( Topics: Albizzia; Animals; Dose-Response Relationship, Drug; Drug Design; Furans; Inhibitory Concentration 50; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Nitric Oxide; Phenols; Phytochemicals; Plant Bark; RAW 264.7 Cells; Structure-Activity Relationship | 2020 |
Synthesis of 3-benzoyl-4-benzylfurans structural related to furolignans.
Furolignan-type natural products, possessing important biological properties, have been synthesized from a commercially available furan. The elaborated synthetic strategy is based on an innovative Friedel-Crafts reaction starting from an alcohol or a carboxylic acid and triflic anhydride as promoter. Through this synthetic strategy, furolignans having two different aryl groups have been obtained. The products have been evaluated for their antimicrobial properties on Gram positive and Gram negative bacteria, in order to compare their biological activities with those of natural analogues. Topics: Alcohols; Anti-Bacterial Agents; Carboxylic Acids; Furans; Gram-Negative Bacteria; Gram-Positive Bacteria; Lignans; Sulfonamides | 2020 |
Acetal-initiated Prins bicyclization for the synthesis of hexahydrofuro-[3,4-c]furan lignans and octahydropyrano[3,4-c]pyran derivatives.
An acetal-initiated Prins bicyclization approach has been developed for the stereoselective synthesis of hexahydrofuro[3,4-c]furan lignans. This also provides a direct way to generate a new series of octahydropyrano[3,4-c]pyran derivatives in a single-step process. Topics: Acetals; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cyclization; Furans; Lignans; Molecular Conformation; Pyrans | 2014 |
Improved stereoselective synthesis of optically active methylene lactone, key intermediate for the synthesis of 1,2-oxidized furofuran lignan, by direct alpha-methylenation to butanolide.
(3R)-3-[(1R)-1-(tert-Butyldimethylsilyl)oxy-1-(2-methoxy-4,5-methylenedioxyphenyl) methyl]-2-methylene-4-butanolide, which is a key intermediate for the synthesis of 1,2-oxidized furofuran lignan, was stereoselectively synthesized from L-glutamic acid by applying direct methylenation to butanolide. Topics: 4-Butyrolactone; Dioxoles; Furans; Hydrocarbons; Lignans; Magnetic Resonance Spectroscopy; Methane; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism | 2000 |