Page last updated: 2024-09-04

lidorestat and thiazoles

lidorestat has been researched along with thiazoles in 3 studies

Compound Research Comparison

Studies
(lidorestat)
Trials
(lidorestat)
Recent Studies (post-2010)
(lidorestat)
Studies
(thiazoles)
Trials
(thiazoles)
Recent Studies (post-2010) (thiazoles)
60233,1792,10012,330

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dicioccio, AT; Geraci, LS; Gunn, DE; Jacot, JL; Jones, JH; Jones, ML; Mitschler, A; Petrova, T; Podjarny, AD; Sawicki, DR; Sredy, J; Van Zandt, MC1
DiCioccio, T; Goldberg, IJ; Homma, S; Hu, Y; Nichols, AJ; Noh, HL; Okajima, K; Park, TS1
Banerjee, S; Ceyhan, MS; Díez-Dacal, B; Majekova, M; Milackova, I; Pérez-Sala, D; Soltesova Prnova, M; Stefek, M1

Other Studies

3 other study(ies) available for lidorestat and thiazoles

ArticleYear
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: Aldehyde Reductase; Animals; Cataract; Chronic Disease; Crystallography, X-Ray; Diabetes Complications; Diabetes Mellitus, Experimental; Humans; Indoleacetic Acids; Lens, Crystalline; Male; Models, Molecular; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Structure-Activity Relationship; Thiazoles; Tissue Distribution

2005
Regulation of plasma fructose and mortality in mice by the aldose reductase inhibitor lidorestat.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:2

    Topics: Aldehyde Reductase; Animals; Biological Phenomena; Blood; Blood Glucose; Enzyme Inhibitors; Fructose; Humans; Indoleacetic Acids; Mice; Mice, Knockout; Mortality; Streptozocin; Thiazoles

2009
[5-(Benzyloxy)-1H-indol-1-yl]acetic acid, an aldose reductase inhibitor and PPARγ ligand.
    Acta biochimica Polonica, 2015, Volume: 62, Issue:3

    Topics: Acetic Acid; Aldehyde Reductase; Animals; Binding Sites; Diabetes Mellitus; Enzyme Inhibitors; Humans; Indoleacetic Acids; Indoles; Inhibitory Concentration 50; Kidney; Lens, Crystalline; Ligands; Luciferases; Male; Molecular Conformation; PPAR gamma; Protein Binding; Rats; Rats, Wistar; Thiazoles

2015