Page last updated: 2024-08-17

lactose and mk 458

lactose has been researched along with mk 458 in 177 studies

Research

Studies (177)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's58 (32.77)18.2507
2000's119 (67.23)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cutler, NR; Hand, EL; McLean, LF; Porras, AG; Reines, SA; Sramek, JJ1
Diederich, NJ; Goetz, CG1
Ahlskog, JE; Bailey, PA; Muenter, MD; Stevens, PM1
Dornbach, G; Hille, P; Kammann, J; Vollenberg, C1
Ahlskog, JE; Ahrens, S; Block, GA; Cedarbaum, JM; Cyhan, G; Goetz, CG; Koller, WC; LeWitt, PA; Liss, C; McLean, L1
Chen, SC; Kao, YH; Liu, CH; Sheu, MT; Sokoloski, TD1
Hollinger, JO; Jin, L; Kenley, R; Marden, L; Ron, E; Turek, T1
Brewer, JT; Drake, MM; Nelson, JD; Tuley, M1
Topping, D1
Bowtell, R; Davies, MC; Mansfield, P; Melia, CD; Peters, A; Rajabi-Siahboomi, AR; Sharp, JC1
Block, GA; Cutler, NR; Sramek, JJ1
Matchette, LS; Vegella, TJ1
Maejima, T; Matsukawa, Y; Osawa, T; Yamakita, H1
Skeidsvoll, J; Ueland, PM1
Drennen, JK; Kirsch, JD1
Friedman, M; Goldberger, A; Hoffman, A; Katzhendler, I1
Fassihi, R; Kim, H2
Sunada, H; Suzuki, H1
Ju, RT; Nixon, PR; Patel, MV1
Ashby, J; Lefevre, PA1
Bertoni, M; Bolhuis, GK; Bonferoni, MC; Caramella, C; Ferrari, F; Rossi, S1
Fassihi, R; Johnson, B; Yang, L1
Aso, Y; Kojima, S; Yoshioka, S1
Ford, JL1
Bignardi, G; Cafaggi, S; Gatti, P; Parodi, B; Russo, E1
Ahrabi, SF; Graffner, C; Sande, SA; Waaler, T1
Cui, JH; Lee, BJ; Ryu, SG2
Frohoff-Hülsmann, MA; Lippold, BC; Schmitz, A1
Kanaya, Y; Nakano, T; Yuasa, H1
Peh, KK; Wong, CF; Yuen, KH1
Fang, CL; Fang, JY; Lin, HH; Sung, KC1
Augsburger, LL; Hussain, AS; Malinowski, HJ; Nellore, RV; Rekhi, GS; Tillman, LG1
Diestelhorst, M; Grunthal, S; Süverkrüp, R1
Carpineto, P; Ciancaglini, M; Costagliola, C; Di Bonaventura, G; Falconio, G; Gallenga, PE; Mastropasqua, L; Piccolomini, R1
Ford, JL; McCrystal, CB; Rajabi-Siahboomi, AR2
Bouler, JM; Daculsi, G; Gauthier, O; Grimandi, G; Weiss, P1
Aguado, E; Bosco, J; Bouler, JM; Daculsi, G; Gauthier, O; Weiss, P1
Bodmeier, R; Krögel, I2
Bettini, R; Colombo, P; Peppas, NA1
Hugkulstone, CE1
Conte, U; Machiste, EO; Maggi, L; Torre, ML1
Collett, JH; Fell, JT; Macleod, GS; Sharma, HL; Smith, AM1
Ghaly, ES; Vargas, CI1
Cheng, K; Song, X; Sun, L; Zhang, J; Zhu, J1
Collett, JH; Fell, JT; Macleod, GS1
Albrecht, HH; Daggy, BP; Davidson, MH; Maki, KC; Malik, KC; O'Mullane, J1
Bodmeier, R; Kranz, H; Peppas, NA; Siepmann, J2
Craig, DQ; Lever, TJ; Price, DM; Reading, M; Royall, PG1
Kasraian, K; Kuzniar, AA; Wilson, GG; Wood, JA1
Schwartz, JB; Tang, L; Wigent, RJ1
Heng, PW; Tan, YT; Wan, LS1
Cox, PJ; Khan, KA; Munday, DL; Sujja-areevath, J1
Bonferoni, MC; Caramella, C; Gustafsson, C; Lennholm, H; Nyström, C1
Bouler, JM; Daculsi, G; Rohanizadeh, R; Weiss, P1
Barra, J; Doelker, E; Falson-Rieg, F; Ullrich, A1
Baumgartner, S; Kristl, J; Vodopivec, P; Vrecer, F; Zorko, B1
Bruni, R; Conte, U; Maggi, L1
Azuara-Blanco, A; Benedetto, DA; Dua, HS1
Asbill, CS; El-Kattan, AF; Michniak, BB1
Hadgraft, J; Iervolino, M; Raghavan, SL1
Ahrabi, SF; Graffner, C; Heinämäki, J; Sande, SA1
Daniels, R; Schulz, MB1
Ford, JL; Rajabi-Siahboomi, AR; Rubinstein, MH; Sadeghi, F2
Ding, D; Li, H; Yan, G; Zhang, R1
Albertin, A; Di Stefano, M; Govoni, E; Hatzopoulos, S; Martini, A; Rubini, R1
Peh, KK; Wong, CF1
Garcia-Andreu, J; Leon, MJ; Lucero, MJ; Roman, F1
Espinoza, R; Hong, E; Villafuerte, L1
Blazek-Welsh, AI; Chopra, SK; Fahie, BJ; Fyfe, CA; Grondey, H1
Hoag, SW; Nyamweya, N1
Endo, H; Ishikawa, T; Matsumoto, M; Takayama, K; Watanabe, Y1
Porter, SC; Schnaare, RL; Schwartz, JB; Tang, L; Wigent, RJ1
Alvarez-Lorenzo, C; Concheiro, A; Duro, R; Gutiérrez de Rubalcava, C; Rodriguez, JL; Seijo, B1
Choi, H; Han, J; Jung, J; Kim, C; Lee, M; Park, K; Rhee, C; Yong, CS1
Akev, N; Birteksöz, S; Can, A; Gerçeker, A; Ozsoy, Y; Tunçel, T1
Qadan, A; Süss, W1
MacRae, RJ; Ross, AC; Stevens, HN; Walther, M1
Attwood, D; Hou, WM; Iwatsu, M; Kawasaki, N; Miyazaki, S; Nakamura, T1
Pisek, R; Planinsek, O; Srcic, S; Trojak, A1
Alaaddinoğlu, E; Capan, Y; Dalkara, T; Hincal, AA; Ikinci, G; Senel, S1
Kotsilkova, R; Krusteva, E; Michailova, V; Minkov, E; Titeva, S1
Assaf, P; Baluom, M; Friedman, M; Haj-Yehia, AI; Rubinstein, A1
Christensen, KL; Kristensen, HG; Pedersen, GP2
Davis, AF; Hadgraft, J; Raghavan, SL; Trividic, A1
Cappello, B; Hadgraft, J; Iervolino, M; Raghavan, SL1
Baluom, M; Friedman, M; Rubinstein, A1
Bettini, R; Catellani, PL; Colombo, P; Massimo, G; Peppas, NA; Santi, P1
Groves, MJ; Xu, G1
Betageri, GV; Deshmukh, DV; Gupta, RB1
Amaral, MH; Ferreira, DC; Lobo, JM1
Busetti, C; Gazzaniga, A; Giordano, F; Maroni, A; Sangalli, ME; Zema, L1
Ford, JL; Hino, T2
Kim, DD; Kim, MK; Lee, CH; Zhao, H1
Rajbhandari, S; Sakr, A; Takka, S1
Choi, HG; Jung, JH; Kim, CK; Rhee, JD; Yong, CS1
Srichana, T; Suedee, R1
Bi, D; Wei, Z; Yu, Z1
Kawashima, Y; Kojima, H; Takeuchi, H; Yamamoto, H1
Haslam, JL; Rao, VM; Stella, VJ1
Chan, LW; Easterbrook, MG; Heng, PW; Li, X1
Fell, JT; Ofori-Kwakye, K1
Ceschel, GC; Lombardi Borgia, S; Maffei, P; Ronchi, C; Rossi, S1
Ayres, JW; Kapsi, SG1
Beckert, T; Cadé, D; Cole, ET; Connor, AL; Petereit, HU; Schminke, C; Scott, RA; Wilding, IR1
Ito, K; Kondo, S; Kuzuya, M1
Turkoglu, M; Ugurlu, T1
Gohel, MC; Sumitra G, M1
Lin, JM; Shy, JD; Tsai, YY1
Aggarwal, S; Mishra, B; Singh, PN1
Eldin, SG; Hosny, H; Hosny, M1
Calvo, B; de la Cruz, Y; Gascón, AR; Hernández, RM; Pedraz, JL; Solinís, MA1
Choi, HS; Khang, G; Lee, HB; Rhee, JM; Seo, SA1
Roshdy, MN; Schnaare, RL; Schwartz, JB; Sugita, ET1
Cabelka, TD; Mahaguna, V; Reynolds, TD; Sykora, MA; Williams, RO1
Casiraghi, A; Cilurzo, F; Minghetti, P; Montanari, L1
Artusi, M; Colombo, P; Sacchetti, C; Santi, P1
Hollowood, TA; Linforth, RS; Taylor, AJ1
Chien, YW; Daggy, BP; Li, S; Lin, S; Mirchandani, HL1
Lee, CH; Wang, Y2
Frutos, G; Frutos, P; Torrado, S; Virto, MR1
Martínez González, I; Villafuerte Robles, L1
Du, Q; Liu, GJ; Ping, QN1
Bi, KS; Guo, T; Li, X; Ma, Y; Song, HT; Zhang, RH1
Zhang, N; Zhu, JB1
He, WL; Wu, F; Zhang, Y; Zhang, ZR1
Liang, WQ; Wei, XH; Wu, JJ1
Ding, JS; Jiang, XH; Yuan, M1
Casiraghi, A; Cilurzo, F; Minghetti, P; Montanari, L; Selmin, F1
Augustin, AJ; Dick, HB; Pakula, T; Pfeiffer, N1
Araman, A; Değim, T; Gönüllü, U; Uner, M; Yener, G1
Bhaskar, P; Krishnaiah, YS; Satyanarayana, V2
Du, M; Flanagan, JH; Lin, B; Ma, Y1
Agarwal, SP; Khanna, R; Kumar, A1
Hamed, E; Sakr, A1
Medvecká, G; Rabisková, M; Vostalová, L1
Fell, JT; Ofori-Kwakye, K; Sharma, HL; Smith, AM1
Mahaguna, V; Sykora, MA; Williams, RO1
Mehuys, E; Remon, JP; Vervaet, C1
Adrangui, M; Akbari, J; Farid, D; Nokhodchi, A; Saeedi, M; Siahi-Shadbad, MR1
Chow, MS; Fu, XC; Liang, WQ; Wang, GP1
Ando, M; Danjo, K; Ozeki, Y; Watanabe, Y1
Inada, K; Matsuhisa, K; Ohtori, A; Terayama, H; Yasueda, S1
Augustin, AJ; Dick, HB1
Huyghebaert, N; Remon, JP; Vermeire, A1
Chambers, AR; Florence, AJ; McConville, JT; Ross, AC; Smith, G; Stevens, HN1
Craig, DQ; Grandy, DB; Hussain, S; Reading, M1
Ariën, A; Brewster, ME; Bruining, M; Chun, I; Mensch, J; Noppe, M; Peeters, J; Rosenblatt, J; Van Dijck, A; Verreck, G1
Foppoli, A; Gazzaniga, A; Giordano, F; Maroni, A; Sangalli, ME; Zema, L1
Dale, RM; Schnell, G; Wong, JP1
Hu, JH; Li, FQ1
Fu, XC; Liang, WQ; Wang, GP; Wang, YH1
Chang, JS; Huang, YB; Takayama, K; Tsai, YH; Wu, PC; Yang, WC1
Fell, JT; Odeku, OA1
Broussali, T; Kachrimanis, K; Kiortsis, S; Malamataris, S1
Gutta, K; Munjal, M; Prodduturi, S; Repka, MA; Stodghill, SP1
Ci, L; Tang, X; Tian, X1
Chen, XC; Du, SY; Wu, Q1
Li, YQ; Pei, XF; Su, N; Yong, L; Zhou, Y1
Florence, AJ; McConville, JT; Ross, AC; Stevens, HN1
Qussi, B; Suess, WG1
Ho, HO; Lin, LH; Lin, YK; Sheu, MT; Wang, CY1
Florence, AT; Ruenraroengsak, P1
Augustijns, P; Korst, A; Mehuys, E; Mols, R; Porter, C; Remon, JP; Van Bortel, L; Vervaet, C1
El-Nabarawi, MA1
Cao, QR; Choi, YW; Cui, JH; Lee, BJ1
Baillie, AJ; Gibson, I; McInnes, FJ; Nolan, A; Stevens, HN; Thapa, P; Watson, DG; Welling, PG1
Moribe, K; Pongpeerapat, A; Tozuka, Y; Yamamoto, K1

Reviews

4 review(s) available for lactose and mk 458

ArticleYear
Dopaminergic agonists in the treatment of Parkinson's disease.
    Neurologic clinics, 1992, Volume: 10, Issue:2

    Topics: Apomorphine; Bromocriptine; Dopamine Agents; Humans; Lactose; Lisuride; Methylcellulose; Oxazines; Parkinson Disease; Pergolide; Receptors, Dopamine

1992
Hydroxypropylmethylcellulose, viscosity, and plasma cholesterol control.
    Nutrition reviews, 1994, Volume: 52, Issue:5

    Topics: Animals; Cholesterol; Cholesterol, LDL; Female; Gastrointestinal Contents; Humans; Hypercholesterolemia; Lactose; Male; Methylcellulose; Oxazines; Solubility; Viscosity

1994
Thermal analysis of hydroxypropylmethylcellulose and methylcellulose: powders, gels and matrix tablets.
    International journal of pharmaceutics, 1999, Mar-15, Volume: 179, Issue:2

    Topics: Calorimetry, Differential Scanning; Gels; Lactose; Methylcellulose; Oxazines; Powders; Tablets

1999
Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature.
    Cornea, 2002, Volume: 21, Issue:2

    Topics: Acute Disease; Humans; Intraoperative Period; Lactose; Lubrication; Male; Methylcellulose; Middle Aged; Mitomycin; Ophthalmologic Surgical Procedures; Oxazines; Postoperative Complications; Pterygium; Sclera; Scleral Diseases; Wound Healing

2002

Trials

14 trial(s) available for lactose and mk 458

ArticleYear
[Controlled clinical study of two viscoelastic substances].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1991, Volume: 88, Issue:5

    Topics: Cataract Extraction; Humans; Hyaluronic Acid; Intraocular Pressure; Lactose; Lenses, Intraocular; Methylcellulose; Oxazines; Postoperative Complications

1991
Effect of MK-458 (HPMC) in Parkinson's disease previously untreated with dopaminergic drugs. A double-blind, placebo-controlled multicenter study.
    Clinical neuropharmacology, 1991, Volume: 14, Issue:4

    Topics: Aged; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Lactose; Male; Methylcellulose; Middle Aged; Oxazines; Parkinson Disease

1991
In-vitro and in-vivo studies of the diclofenac sodium controlled-release matrix tablets.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:5

    Topics: Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Hardness; Humans; Lactose; Male; Methylcellulose; Oxazines; Solubility; Tablets

1995
Preparation of controlled release granules of TA-5707F using enteric polymers and ethylcellulose, and their in vivo evaluation.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Adult; Animals; Anti-Allergic Agents; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dogs; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Lactose; Male; Methylcellulose; Niacinamide; Oxazines; Solubility; Tablets, Enteric-Coated

1996
Dry Drops: a new preservative-free drug delivery system.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1999, Volume: 237, Issue:5

    Topics: Adult; Cross-Over Studies; Drug Delivery Systems; Eye; Female; Humans; Lactose; Male; Methylcellulose; Ophthalmic Solutions; Oxazines; Preservatives, Pharmaceutical; Safety; Surveys and Questionnaires

1999
Cholesterol lowering with high-viscosity hydroxypropylmethylcellulose.
    The American journal of cardiology, 1999, Nov-15, Volume: 84, Issue:10

    Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lactose; Male; Methylcellulose; Middle Aged; Oxazines; Viscosity

1999
In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine.
    Die Pharmazie, 2000, Volume: 55, Issue:10

    Topics: Absorption; Adhesives; Adult; Animals; Anticonvulsants; Carbamazepine; Cattle; Female; Humans; In Vitro Techniques; Irritants; Kinetics; Lactose; Male; Methylcellulose; Mouth Mucosa; Oxazines; Solubility; Tablets

2000
In vitro and in vivo evaluation of an oral system for time and/or site-specific drug delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, May-18, Volume: 73, Issue:1

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Colon; Drug Carriers; Drug Delivery Systems; Humans; Lactose; Male; Methylcellulose; Middle Aged; Oxazines; Radiopharmaceuticals; Technetium Tc 99m Pentetate

2001
Physicochemical characterization and evaluation of buccal adhesive tablets containing omeprazole.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:5

    Topics: Adhesives; Administration, Oral; Adult; Alginates; Anti-Ulcer Agents; Carboxymethylcellulose Sodium; Drug Delivery Systems; Drug Stability; Glucuronic Acid; Hexuronic Acids; Humans; Lactose; Magnesium Oxide; Male; Methylcellulose; Omeprazole; Oxazines; Polymers; Saliva; Solubility; Tablets

2001
Processing factors in development of solid solution formulation of itraconazole for enhancement of drug dissolution and bioavailability.
    International journal of pharmaceutics, 2001, Oct-23, Volume: 229, Issue:1-2

    Topics: Adult; Antifungal Agents; Biological Availability; Calorimetry, Differential Scanning; Cross-Over Studies; Drug Compounding; Excipients; Glycerol; Humans; Itraconazole; Lactose; Methylcellulose; Oxazines; Particle Size; Pharmaceutical Solutions; Pharmaceutical Vehicles; Polyethylene Glycols; Solubility

2001
Enteric coated HPMC capsules designed to achieve intestinal targeting.
    International journal of pharmaceutics, 2002, Jan-01, Volume: 231, Issue:1

    Topics: Capsules; Cross-Over Studies; Drug Delivery Systems; Female; Humans; Intestinal Mucosa; Intestines; Lactose; Male; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Polymethacrylic Acids; Radionuclide Imaging; Solubility; Tablets, Enteric-Coated

2002
Combined lidocaine 1% and hydroxypropyl methylcellulose 2.25% as a single anesthetic/ viscoelastic agent in phacoemulsification.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:5

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Capsulorhexis; Drug Therapy, Combination; Humans; Lactose; Lens Implantation, Intraocular; Lidocaine; Methylcellulose; Oxazines; Pain Measurement; Patient Satisfaction; Phacoemulsification; Prospective Studies

2002
Human bioavailability of propranolol from a matrix-in-cylinder system with a HPMC-Gelucire core.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Oct-20, Volume: 107, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Algorithms; Animals; Area Under Curve; Biological Availability; Biological Transport, Active; Biotransformation; Caco-2 Cells; Cross-Over Studies; Drug Delivery Systems; Excipients; Female; Food-Drug Interactions; Humans; In Vitro Techniques; Intestinal Absorption; Lactose; Male; Methylcellulose; Middle Aged; Oxazines; Polyethylene Glycols; Propranolol; Rats

2005
Formulation, release characteristics and bioavailability of novel monolithic hydroxypropylmethylcellulose matrix tablets containing acetaminophen.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Nov-28, Volume: 108, Issue:2-3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Biological Availability; Chemistry, Pharmaceutical; Excipients; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Lactose; Male; Methylcellulose; Oxazines; Solubility; Surface-Active Agents; Tablets; Water

2005

Other Studies

159 other study(ies) available for lactose and mk 458

ArticleYear
Pharmacokinetics and dose proportionality of D2-agonist MK-458 (HPMC) in parkinsonism.
    Clinical pharmacokinetics, 1992, Volume: 22, Issue:3

    Topics: Administration, Oral; Aged; Antiparkinson Agents; Delayed-Action Preparations; Dopamine Agents; Dose-Response Relationship, Drug; Female; Humans; Lactose; Male; Methylcellulose; Middle Aged; Oxazines; Parkinson Disease; Tablets

1992
Dopamine agonist treatment of fluctuating parkinsonism. D-2 (controlled-release MK-458) vs combined D-1 and D-2 (pergolide)
    Archives of neurology, 1992, Volume: 49, Issue:5

    Topics: Adult; Aged; Antiparkinson Agents; Carbidopa; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Lactose; Levodopa; Male; Methylcellulose; Middle Aged; Oxazines; Parkinson Disease; Pergolide

1992
Osseous regeneration in the rat calvarium using novel delivery systems for recombinant human bone morphogenetic protein-2 (rhBMP-2).
    Journal of biomedical materials research, 1994, Volume: 28, Issue:10

    Topics: Alginates; Animals; Biocompatible Materials; Bone Morphogenetic Proteins; CHO Cells; Cricetinae; Drug Carriers; Drug Implants; Female; Glucuronic Acid; Growth Substances; Hexuronic Acids; Humans; Lactic Acid; Lactose; Male; Methylcellulose; Microspheres; Oxazines; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Radiography; Rats; Recombinant Proteins; Regeneration; Skull

1994
Evaluation of a physiological tear substitute in patients with keratoconjunctivitis sicca.
    Advances in experimental medicine and biology, 1994, Volume: 350

    Topics: Adult; Aged; Conjunctiva; Cornea; Drug Administration Schedule; Female; Humans; Keratoconjunctivitis Sicca; Lactose; Methylcellulose; Middle Aged; Ophthalmic Solutions; Oxazines; Rose Bengal; Tears

1994
NMR microscopy of hydrating hydrophilic matrix pharmaceutical tablets.
    Magnetic resonance imaging, 1994, Volume: 12, Issue:2

    Topics: Diclofenac; Gels; Lactose; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Tablets

1994
Poor tolerability of MK-458.
    Archives of neurology, 1993, Volume: 50, Issue:9

    Topics: Humans; Lactose; Methylcellulose; Oxazines; Parkinson Disease

1993
Glutaraldehyde retains its disinfectant properties in presence of hydroxypropylmethyl cellulose (HPMC) gel.
    Journal of biomedical materials research, 1996,Summer, Volume: 33, Issue:2

    Topics: Bacillus subtilis; Culture Media; Disinfectants; Glutaral; Lactose; Methylcellulose; Oxazines; Spores, Bacterial; Viscosity

1996
Analysis of RNA by capillary electrophoresis.
    Electrophoresis, 1996, Volume: 17, Issue:9

    Topics: Electrochemistry; Electrophoresis, Capillary; Humans; Lactose; Methylcellulose; Nucleic Acid Denaturation; Oxazines; Particle Size; Polymers; RNA; Temperature; Tumor Cells, Cultured

1996
Near-infrared spectroscopic monitoring of the film coating process.
    Pharmaceutical research, 1996, Volume: 13, Issue:2

    Topics: Calibration; Cellulose; Chemistry, Pharmaceutical; Evaluation Studies as Topic; Lactose; Methylcellulose; Oxazines; Spectrophotometry, Infrared; Tablets

1996
Modeling of drug release from erodible tablets.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:1

    Topics: Amoxicillin; Lactose; Methylcellulose; Models, Chemical; Oxazines; Tablets

1997
Application of a binary polymer system in drug release rate modulation. 1. Characterization of release mechanism.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:3

    Topics: Delayed-Action Preparations; Gels; Hydrogen-Ion Concentration; Kinetics; Lactose; Methylcellulose; Oxazines; Pectins; Prednisolone; Pressure; Tablets; Viscosity

1997
Application of binary polymer system in drug release rate modulation. 2. Influence of formulation variables and hydrodynamic conditions on release kinetics.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:3

    Topics: Delayed-Action Preparations; Diltiazem; Kinetics; Lactose; Methylcellulose; Molecular Weight; Nifedipine; Oxazines; Pectins; Prednisolone; Pressure; Solubility; Tablets; Theophylline

1997
Comparison of nicotinamide, ethylurea and polyethylene glycol as carriers for nifedipine solid dispersion systems.
    Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:10

    Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Drug Carriers; Lactose; Methylcellulose; Niacinamide; Nifedipine; Oxazines; Polyethylene Glycols; Solubility; Urea; X-Ray Diffraction

1997
Diffusion coefficients of polymer chains in the diffusion layer adjacent to a swollen hydrophilic matrix.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:11

    Topics: Diffusion; Lactose; Methylcellulose; Oxazines; Solubility

1997
The weanling male rat as an assay for endocrine disruption: preliminary observations.
    Regulatory toxicology and pharmacology : RTP, 1997, Volume: 26, Issue:3

    Topics: Anastrozole; Androgen Antagonists; Animals; Body Weight; Cyproterone Acetate; Drug Evaluation, Preclinical; Endocrine System Diseases; Female; Lactose; Male; Methylcellulose; Nitriles; Organ Size; Oxazines; Oxazoles; Rats; Rats, Inbred Strains; Toxicology; Triazoles; Uterus; Weaning

1997
On the employment of lambda carrageenan in a matrix system. III. Optimization of a lambda carrageenan-HPMC hydrophilic matrix.
    Journal of controlled release : official journal of the Controlled Release Society, 1998, Feb-12, Volume: 51, Issue:2-3

    Topics: Carrageenan; Delayed-Action Preparations; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Models, Theoretical; Oxazines; Regression Analysis

1998
Determination of continuous changes in the gel layer thickness of poly(ethylene oxide) and HPMC tablets undergoing hydration: a texture analysis study.
    Pharmaceutical research, 1998, Volume: 15, Issue:12

    Topics: Drug Compounding; Drug Delivery Systems; Gels; Lactose; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Polyethylene Glycols; Tablets; Water

1998
The effect of excipients on the molecular mobility of lyophilized formulations, as measured by glass transition temperature and NMR relaxation-based critical mobility temperature.
    Pharmaceutical research, 1999, Volume: 16, Issue:1

    Topics: Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Dextrans; Excipients; Freeze Drying; gamma-Globulins; Lactose; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Polyhydroxyethyl Methacrylate; Povidone; Protons; Temperature

1999
Development and in vitro evaluation of buccoadhesive tablets using a new model substrate for bioadhesion measures: the eggshell membrane.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:3

    Topics: Administration, Oral; Animals; Benzydamine; Carboxymethylcellulose Sodium; Cellulose; Chickens; Diffusion; Drug Compounding; Egg Shell; Excipients; Gelatin; Lactose; Membranes; Methylcellulose; Metronidazole; Mouth Mucosa; Oxazines; Powders; Tablets; Tensile Strength; Tissue Adhesives

1999
Effects of thermal neutron irradiation on some potential excipients for colonic delivery systems.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:4

    Topics: Chromatography, Gas; Drug Stability; Excipients; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Neutrons; Oxazines; Pectins; Polymethacrylic Acids; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Thermogravimetry

1999
Formulation and release characteristics of hydroxypropyl methylcellulose matrix tablet containing melatonin.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:4

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Dose-Response Relationship, Drug; Lactose; Lubrication; Melatonin; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Polymers; Tablets, Enteric-Coated; Viscosity

1999
Aqueous ethyl cellulose dispersions containing plasticizers of different water solubility and hydroxypropyl methylcellulose as coating material for diffusion pellets. I. Drug release rates from coated pellets.
    International journal of pharmaceutics, 1999, Jan-15, Volume: 177, Issue:1

    Topics: Cellulose; Drug Implants; Lactose; Methylcellulose; Osmolar Concentration; Oxazines; Plasticizers; Solubility; Tablets, Enteric-Coated; Temperature; Theophylline; Water

1999
Suppression of agglomeration in fluidized bed coating. II. Measurement of mist size in a fluidized bed chamber and effect of sodium chloride addition on mist size.
    International journal of pharmaceutics, 1999, Feb-01, Volume: 178, Issue:1

    Topics: Chemistry, Pharmaceutical; Lactose; Methylcellulose; Oxazines; Particle Size; Sodium Chloride; Temperature

1999
Formulation and evaluation of controlled release Eudragit buccal patches.
    International journal of pharmaceutics, 1999, Feb-01, Volume: 178, Issue:1

    Topics: Acrylic Resins; Adhesiveness; Administration, Topical; Animals; Carboxymethylcellulose Sodium; Chickens; Delayed-Action Preparations; Drug Delivery Systems; Drug Design; In Vitro Techniques; Lactose; Methylcellulose; Models, Biological; Mouth Mucosa; Oxazines; Polymers; Polyvinyls; Solubility; Viscosity

1999
Transdermal iontophoretic delivery of diclofenac sodium from various polymer formulations: in vitro and in vivo studies.
    International journal of pharmaceutics, 1999, Feb-01, Volume: 178, Issue:1

    Topics: Administration, Cutaneous; Anesthesia; Animals; Cellulose; Chemistry, Pharmaceutical; Diclofenac; Drug Interactions; Humans; In Vitro Techniques; Iontophoresis; Lactose; Male; Methylcellulose; Microdialysis; Oxazines; Polymers; Povidone; Rats; Rats, Wistar; Zingiberales

1999
Identification of critical formulation and processing variables for metoprolol tartrate extended-release (ER) matrix tablets.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, Jun-02, Volume: 59, Issue:3

    Topics: Administration, Oral; Chemistry, Pharmaceutical; Delayed-Action Preparations; Lactose; Methylcellulose; Metoprolol; Oxazines; Regression Analysis; Solubility; Tablets

1999
In vitro viability of external eye microbial flora in hydroxy-propyl-methylcellulose.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1999, Volume: 213, Issue:4

    Topics: Bacteria; Bacterial Physiological Phenomena; Colony Count, Microbial; Eye; Humans; In Vitro Techniques; Lactose; Methylcellulose; Oxazines

1999
Water distribution studies within cellulose ethers using differential scanning calorimetry. 1. Effect of polymer molecular weight and drug addition.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:8

    Topics: Calorimetry, Differential Scanning; Cellulose; Diclofenac; Differential Thermal Analysis; Ethers; Gels; Lactose; Methylcellulose; Molecular Weight; Oxazines; Pharmaceutical Preparations; Propranolol; Thermodynamics; Water

1999
Water distribution studies within cellulose ethers using differential scanning calorimetry. 2. Effect of polymer substitution type and drug addition.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:8

    Topics: Calorimetry, Differential Scanning; Cellulose; Diclofenac; Differential Thermal Analysis; Ethers; Gels; Lactose; Methylcellulose; Molecular Weight; Oxazines; Pharmaceutical Preparations; Propranolol; Thermodynamics; Water

1999
Injectable bone substitute using a hydrophilic polymer.
    Bone, 1999, Volume: 25, Issue:2 Suppl

    Topics: Animals; Biocompatible Materials; Bone Substitutes; Calcium Phosphates; Femur; Implants, Experimental; Injections; Lactose; Materials Testing; Methylcellulose; Oxazines; Rabbits; Rheology; Viscosity

1999
Short-term effects of mineral particle sizes on cellular degradation activity after implantation of injectable calcium phosphate biomaterials and the consequences for bone substitution.
    Bone, 1999, Volume: 25, Issue:2 Suppl

    Topics: Acid Phosphatase; Animals; Biocompatible Materials; Biodegradation, Environmental; Bone Substitutes; Calcium Phosphates; Electron Probe Microanalysis; Female; Femur; Implants, Experimental; Injections; Isoenzymes; Lactose; Materials Testing; Methylcellulose; Microscopy, Electron, Scanning; Minerals; Osseointegration; Oxazines; Particle Size; Rabbits; Tartrate-Resistant Acid Phosphatase

1999
Development of a multifunctional matrix drug delivery system surrounded by an impermeable cylinder.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, Aug-27, Volume: 61, Issue:1-2

    Topics: Drug Delivery Systems; Lactose; Methylcellulose; Oxazines; Tablets; Viscosity

1999
Observation of swelling process and diffusion front position during swelling in hydroxypropyl methyl cellulose (HPMC) matrices containing a soluble drug.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, Aug-27, Volume: 61, Issue:1-2

    Topics: Diffusion; Drug Delivery Systems; Lactose; Methylcellulose; Oxazines; Solubility

1999
Suction posterior capsulorhexis.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:9

    Topics: Capsulorhexis; Humans; Lactose; Lens Implantation, Intraocular; Methylcellulose; Oxazines; Phacoemulsification; Suction

1999
Formulation of biphasic release tablets containing slightly soluble drugs.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 1999, Volume: 48, Issue:1

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Excipients; Ketoprofen; Kinetics; Lactose; Methylcellulose; Oxazines; Particle Size; Pharmaceutical Preparations; Praziquantel; Solubility; Tablets

1999
Floating or pulsatile drug delivery systems based on coated effervescent cores.
    International journal of pharmaceutics, 1999, Oct-05, Volume: 187, Issue:2

    Topics: Cellulose; Drug Delivery Systems; Lactose; Methylcellulose; Oxazines; Plasticizers; Solubility; Time Factors

1999
Selective drug delivery to the colon using pectin:chitosan:hydroxypropyl methylcellulose film coated tablets.
    International journal of pharmaceutics, 1999, Oct-05, Volume: 187, Issue:2

    Topics: Adult; Chitin; Chitosan; Colon; Drug Delivery Systems; Humans; Lactose; Male; Methylcellulose; Middle Aged; Oxazines; Pectins; Solubility; Tablets; Technetium; Time Factors

1999
Kinetic release of theophylline from hydrophilic swellable matrices.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:9

    Topics: Administration, Oral; Excipients; Lactose; Methylcellulose; Models, Theoretical; Oxazines; Polymers; Solubility; Solvents; Stearic Acids; Tablets; Theophylline; Time Factors

1999
Studies of hydroxypropyl methylcellulose donut-shaped tablets.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:9

    Topics: Diltiazem; Lactose; Methylcellulose; Oxazines; Solubility; Tablets; Theophylline; Time Factors

1999
An in vitro investigation into the potential for bimodal drug release from pectin/chitosan/HPMC-coated tablets.
    International journal of pharmaceutics, 1999, Oct-15, Volume: 188, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Chitin; Chitosan; Delayed-Action Preparations; Drug Compounding; Hydrogen-Ion Concentration; Kinetics; Lactose; Methylcellulose; Oxazines; Pectins; Tablets; Tablets, Enteric-Coated; Time Factors; Water

1999
Controlled release of dual drug-loaded hydroxypropyl methylcellulose matrix tablet using drug-containing polymeric coatings.
    International journal of pharmaceutics, 1999, Oct-15, Volume: 188, Issue:1

    Topics: Anticonvulsants; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dose-Response Relationship, Drug; Lactose; Melatonin; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Plasticizers; Polymers; Tablets; Tablets, Enteric-Coated; Talc

1999
HPMC-matrices for controlled drug delivery: a new model combining diffusion, swelling, and dissolution mechanisms and predicting the release kinetics.
    Pharmaceutical research, 1999, Volume: 16, Issue:11

    Topics: Delayed-Action Preparations; Diffusion; Lactose; Methylcellulose; Models, Chemical; Oxazines; Propranolol; Reproducibility of Results; Solubility; Time Factors

1999
An investigation into the use of micro-thermal analysis for the solid state characterisation of an HPMC tablet formulation.
    International journal of pharmaceutics, 1999, Dec-01, Volume: 192, Issue:1

    Topics: Differential Thermal Analysis; Drug Compounding; Excipients; Ibuprofen; Lactose; Methylcellulose; Microscopy, Atomic Force; Oxazines; Tablets

1999
Developing an injectable formula containing an oxygen-sensitive drug: a case study of danofloxacin injectable.
    Pharmaceutical development and technology, 1999, Volume: 4, Issue:4

    Topics: Anti-Infective Agents; Antioxidants; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Fluoroquinolones; Injections; Lactose; Methylcellulose; Microspheres; Models, Theoretical; Oxazines; Oxygen; Solubility; Surface Properties; Water

1999
Drug release from film-coated chlorpheniramine maleate nonpareil beads: water influx and development of a new drug release model.
    Pharmaceutical development and technology, 1999, Volume: 4, Issue:4

    Topics: Algorithms; Chlorpheniramine; Delayed-Action Preparations; Drug Compounding; Excipients; Kinetics; Lactose; Methylcellulose; Microspheres; Models, Theoretical; Oxazines; Particle Size; Solubility; Surface Properties; Water

1999
Mixed polymer coating for modified release from coated spheroids.
    Pharmaceutical development and technology, 1999, Volume: 4, Issue:4

    Topics: Carboxymethylcellulose Sodium; Drug Compounding; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Microspheres; Oxazines; Particle Size; Pharmaceutic Aids; Pharmaceutical Vehicles; Polyethylene Glycols; Povidone; Solubility

1999
Development and evaluation of a multiple-unit oral sustained release dosage form for S(+)-ibuprofen: preparation and release kinetics.
    International journal of pharmaceutics, 1999, Dec-20, Volume: 193, Issue:1

    Topics: Capsules; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Excipients; Gelatin; Ibuprofen; In Vitro Techniques; Karaya Gum; Lactose; Methylcellulose; Oxazines; Polysaccharides, Bacterial; Statistics as Topic; Talc; Time Factors

1999
Characterisation of particle properties and compaction behaviour of hydroxypropyl methylcellulose with different degrees of methoxy/hydroxypropyl substitution.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 9, Issue:2

    Topics: Compressive Strength; Densitometry; Elasticity; Lactose; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Porosity; Powders; Solubility; Surface Properties; Tablets

1999
Crystal polymer interaction with new injectable bone substitute; SEM and Hr TEM study.
    Journal of biomedical materials research, 2000, Volume: 50, Issue:1

    Topics: Bone Substitutes; Calcium Phosphates; Crystallization; Lactose; Methylcellulose; Microscopy, Electron; Microscopy, Electron, Scanning; Oxazines

2000
Color as an indicator of the organization and compactibility of binary powder mixes.
    Pharmaceutical development and technology, 2000, Volume: 5, Issue:1

    Topics: Cellulose; Color; Colorimetry; Ibuprofen; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Niflumic Acid; Oxazines; Particle Size; Powders; Spectrum Analysis; Surface Properties; Tablets; Tensile Strength

2000
Optimisation of floating matrix tablets and evaluation of their gastric residence time.
    International journal of pharmaceutics, 2000, Feb-15, Volume: 195, Issue:1-2

    Topics: Administration, Oral; Animals; Biological Availability; Delayed-Action Preparations; Dogs; Gastrointestinal Transit; Lactose; Methylcellulose; Oxazines; Radiography; Stomach; Tablets; Technology, Pharmaceutical; Time Factors

2000
High molecular weight polyethylene oxides (PEOs) as an alternative to HPMC in controlled release dosage forms.
    International journal of pharmaceutics, 2000, Feb-15, Volume: 195, Issue:1-2

    Topics: Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Excipients; Lactose; Methylcellulose; Molecular Weight; Oxazines; Polyethylene Glycols; Tablets

2000
Protection of corneal endothelium from irrigation damage: a comparison of sodium hyaluronate and hydroxypropylmethylcellulose.
    Eye (London, England), 2000, Volume: 14 ( Pt 1)

    Topics: Animals; Azo Compounds; Cataract Extraction; Coloring Agents; Endothelium, Corneal; Hyaluronic Acid; In Vitro Techniques; Intraoperative Care; Lactose; Methylcellulose; Oxazines; Photometry; Suction; Swine; Therapeutic Irrigation

2000
The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems.
    International journal of pharmaceutics, 2000, Apr-05, Volume: 198, Issue:2

    Topics: Animals; Female; Hydrocortisone; Hydrogels; Lactose; Methylcellulose; Mice; Mice, Hairless; Oxazines; Permeability; Skin; Solubility; Terpenes

2000
Membrane penetration enhancement of ibuprofen using supersaturation.
    International journal of pharmaceutics, 2000, Apr-05, Volume: 198, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cyclodextrins; Diffusion; Drug Stability; Ibuprofen; Lactose; Methylcellulose; Oxazines; Permeability; Solubility

2000
Influence of neutron activation factors on matrix tablets for site specific delivery to the colon.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 10, Issue:3

    Topics: Amides; Analysis of Variance; Chemical Phenomena; Chemistry, Physical; Colon; Drug Compounding; Excipients; Hardness; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Neutrons; Oxazines; Pectins; Polymethacrylic Acids; Ropivacaine; Samarium; Solubility; Stearates; Tablets

2000
Hydroxypropylmethylcellulose (HPMC) as emulsifier for submicron emulsions: influence of molecular weight and substitution type on the droplet size after high-pressure homogenization.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2000, Volume: 49, Issue:3

    Topics: Drug Compounding; Emulsions; Lactose; Methylcellulose; Molecular Weight; Oxazines; Particle Size; Pressure; Surface Tension; Temperature; Triglycerides; Viscosity

2000
Comparative study of drug release from pellets coated with HPMC or Surelease.
    Drug development and industrial pharmacy, 2000, Volume: 26, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Compounding; Lactose; Methylcellulose; Oxazines; Solubility; Water

2000
Preparation and evaluation of a sustained-release formulation of nifedipine HPMC tablets.
    Drug development and industrial pharmacy, 2000, Volume: 26, Issue:6

    Topics: Absorption; Animals; Antihypertensive Agents; Biological Availability; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dogs; Injections, Intravenous; Lactose; Methylcellulose; Nifedipine; Oxazines; Tablets

2000
An animal model based on the Sprague Dawley rat for the evaluation of ototoxicity.
    Annals of the New York Academy of Sciences, 1999, Nov-28, Volume: 884

    Topics: Acoustic Stimulation; Adjuvants, Immunologic; Animals; Disease Models, Animal; Ear, Middle; Evoked Potentials, Auditory, Brain Stem; Hyaluronic Acid; Lactose; Methylcellulose; Microscopy, Electron; Mucous Membrane; Oxazines; Rats; Rats, Sprague-Dawley

1999
Application of similarity factor in development of controlled-release diltiazem tablet.
    Drug development and industrial pharmacy, 2000, Volume: 26, Issue:7

    Topics: Antihypertensive Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Drug Carriers; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Oxazines; Polysaccharides, Bacterial; Tablets

2000
A study of the spread surface of polymeric dispersions of Eudragit.
    Drug development and industrial pharmacy, 2000, Volume: 26, Issue:7

    Topics: Acrylic Resins; Lactose; Methylcellulose; Models, Theoretical; Oxazines; Polymers; Polymethacrylic Acids; Rheology; Stress, Mechanical

2000
Calculation of the required size and shape of hydroxypropyl methylcellulose matrices to achieve desired drug release profiles.
    International journal of pharmaceutics, 2000, May-25, Volume: 201, Issue:2

    Topics: Algorithms; Chlorpheniramine; Delayed-Action Preparations; Drug Carriers; Lactose; Methylcellulose; Models, Theoretical; Oxazines; Particle Size; Propranolol; Reproducibility of Results

2000
Influence of admixed citric acid on the release profile of pelanserin hydrochloride from HPMC matrix tablets.
    International journal of pharmaceutics, 2000, May-25, Volume: 201, Issue:2

    Topics: Antihypertensive Agents; Citric Acid; Delayed-Action Preparations; Drug Carriers; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Oxazines; Quinazolines; Regression Analysis; Solubility

2000
NMR imaging investigations of drug delivery devices using a flow-through USP dissolution apparatus.
    Journal of controlled release : official journal of the Controlled Release Society, 2000, Jul-31, Volume: 68, Issue:1

    Topics: Drug Delivery Systems; Lactose; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Tablets

2000
Assessment of polymer-polymer interactions in blends of HPMC and film forming polymers by modulated temperature differential scanning calorimetry.
    Pharmaceutical research, 2000, Volume: 17, Issue:5

    Topics: Calorimetry, Differential Scanning; Cellulose; Crystallization; Kinetics; Lactose; Membranes, Artificial; Methylcellulose; Molecular Weight; Oxazines; Polymers; Povidone

2000
Effect of hydroxypropylmethylcellulose (HPMC) on the release profiles and bioavailability of a poorly water-soluble drug from tablets prepared using macrogol and HPMC.
    International journal of pharmaceutics, 2000, Jul-20, Volume: 202, Issue:1-2

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Excipients; Lactose; Methylcellulose; Nifedipine; Oxazines; Powders; Rabbits; Rats; Tablets

2000
Drug release from film-coated chlorpheniramine maleate nonpareil beads: effect of water-soluble polymer, coating level, and soluble core material.
    Pharmaceutical development and technology, 2000, Volume: 5, Issue:3

    Topics: Anti-Allergic Agents; Chemistry, Pharmaceutical; Chlorpheniramine; Lactose; Mathematics; Methylcellulose; Oxazines; Permeability; Solubility; Sucrose

2000
Interactions between liposomes and hydroxypropylmethylcellulose.
    International journal of pharmaceutics, 2000, Aug-10, Volume: 203, Issue:1-2

    Topics: Adsorption; Drug Carriers; Lactose; Liposomes; Methylcellulose; Molecular Conformation; Oxazines; Solubility; Thermodynamics

2000
Formulation and in vivo evaluation of omeprazole buccal adhesive tablet.
    Journal of controlled release : official journal of the Controlled Release Society, 2000, Sep-03, Volume: 68, Issue:3

    Topics: Adhesiveness; Administration, Oral; Alginates; Animals; Anti-Ulcer Agents; Biological Availability; Chemical Phenomena; Chemistry, Physical; Cricetinae; Evaluation Studies as Topic; Humans; Lactose; Magnesium Oxide; Male; Mesocricetus; Methylcellulose; Mouth Mucosa; Omeprazole; Oxazines; Tablets

2000
In vivo studies on nasal preparations of ciprofloxacin hydrochloride.
    Die Pharmazie, 2000, Volume: 55, Issue:8

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Availability; Calibration; Cellulose; Ciprofloxacin; Excipients; Female; Injections, Intravenous; Lactose; Male; Methylcellulose; Oxazines; Pharmaceutic Aids; Rabbits

2000
Controlled release of carbamazepine from pellets and tablets manufactured with hydroxypropyl methylcellulose.
    Die Pharmazie, 2000, Volume: 55, Issue:8

    Topics: Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Lactose; Methylcellulose; Oxazines; Tablets; Viscosity

2000
Chronopharmaceutical drug delivery from a pulsatile capsule device based on programmable erosion.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:8

    Topics: Delayed-Action Preparations; Drug Delivery Systems; Lactose; Methylcellulose; Oxazines; Propranolol; Tablets; Technology, Pharmaceutical

2000
Oral mucosal bioadhesive tablets of pectin and HPMC: in vitro and in vivo evaluation.
    International journal of pharmaceutics, 2000, Aug-25, Volume: 204, Issue:1-2

    Topics: Adhesives; Animals; Antihypertensive Agents; Delayed-Action Preparations; Diltiazem; Food Additives; Lactose; Male; Methylcellulose; Mouth Mucosa; Oxazines; Pectins; Rabbits; Rats; Tablets

2000
The utilization of surface free-energy parameters for the selection of a suitable binder in fluidized bed granulation.
    International journal of pharmaceutics, 2000, Oct-10, Volume: 207, Issue:1-2

    Topics: Lactose; Methylcellulose; Oxazines; Povidone; Powders; Technology, Pharmaceutical; Thermodynamics

2000
Water uptake and relaxation processes in mixed unlimited swelling hydrogels.
    International journal of pharmaceutics, 2000, Nov-19, Volume: 209, Issue:1-2

    Topics: Absorption; Algorithms; Carboxymethylcellulose Sodium; Elasticity; Hydrogels; Hydrogen-Ion Concentration; Kinetics; Lactose; Methylcellulose; Models, Theoretical; Oxazines; Pharmaceutic Aids; Tablets; Viscosity; Water

2000
Synchronized release of sulpiride and sodium decanoate from HPMC matrices: a rational approach to enhance sulpiride absorption in the rat intestine.
    Pharmaceutical research, 2000, Volume: 17, Issue:9

    Topics: Animals; Antipsychotic Agents; Chemistry, Pharmaceutical; Decanoates; Intestinal Absorption; Intestine, Small; Lactose; Methylcellulose; Oxazines; Rats; Sulpiride

2000
Preparation of redispersible dry emulsions by spray drying.
    International journal of pharmaceutics, 2001, Jan-16, Volume: 212, Issue:2

    Topics: Drug Compounding; Emulsions; Lactose; Methylcellulose; Oxazines; Technology, Pharmaceutical

2001
Crystallization of hydrocortisone acetate: influence of polymers.
    International journal of pharmaceutics, 2001, Jan-16, Volume: 212, Issue:2

    Topics: Crystallization; Gels; Hydrocortisone; Hydrogen Bonding; Lactose; Methylcellulose; Oxazines; Polyethylene Glycols; Povidone

2001
Penetration enhancement of ibuprofen from supersaturated solutions through human skin.
    International journal of pharmaceutics, 2001, Jan-05, Volume: 212, Issue:1

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Crystallization; Cyclodextrins; Diffusion; Humans; Ibuprofen; Lactose; Methylcellulose; Oxazines; Skin

2001
Improved intestinal absorption of sulpiride in rats with synchronized oral delivery systems.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, Jan-29, Volume: 70, Issue:1-2

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Intestinal Absorption; Lactose; Methylcellulose; Oxazines; Quinidine; Rats; Sulpiride; Verapamil

2001
Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, Feb-23, Volume: 70, Issue:3

    Topics: Diclofenac; Drug Delivery Systems; Gels; Lactose; Methylcellulose; Nitrofurantoin; Oxazines; Pyrrolidines; Solubility

2001
Effect of FITC-dextran molecular weight on its release from floating cetyl alcohol and HPMC tablets.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:1

    Topics: Dextrans; Fatty Alcohols; Fluorescein-5-isothiocyanate; Hydrogel, Polyethylene Glycol Dimethacrylate; Lactose; Methylcellulose; Molecular Weight; Oxazines; Tablets

2001
Oral sustained-release bioadhesive tablet formulation of didanosine.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:2

    Topics: Adhesives; Anti-HIV Agents; Delayed-Action Preparations; Didanosine; Excipients; Half-Life; Lactose; Methylcellulose; Oxazines; Solubility; Tablets

2001
Naproxen availability from variable-dose and weight sustained-release tablets.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chemistry, Pharmaceutical; Delayed-Action Preparations; Lactose; Methylcellulose; Naproxen; Oxazines; Particle Size; Tablets

2001
Characterization of the hydroxypropylmethylcellulose-nicotinamide binary system.
    International journal of pharmaceutics, 2001, May-21, Volume: 219, Issue:1-2

    Topics: Algorithms; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Lactose; Methylcellulose; Niacinamide; Oxazines; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Temperature; X-Ray Diffraction

2001
Formulation of a reservoir-type testosterone transdermal delivery system.
    International journal of pharmaceutics, 2001, May-21, Volume: 219, Issue:1-2

    Topics: Administration, Cutaneous; Animals; Delayed-Action Preparations; Drug Delivery Systems; Excipients; Gels; In Vitro Techniques; Lactose; Male; Methylcellulose; Oxazines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Skin Absorption; Solubility; Testosterone; Viscosity

2001
Effect of anionic polymers on the release of propranolol hydrochloride from matrix tablets.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2001, Volume: 52, Issue:1

    Topics: Acrylic Resins; Carboxymethylcellulose Sodium; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Oxazines; Polymethacrylic Acids; Propranolol; Solubility; Spectrophotometry, Ultraviolet; Tablets

2001
Study of drug release from pellets coated with Surelease containing hydroxypropylmethylcellulose.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:5

    Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Delayed-Action Preparations; Diclofenac; Dopamine Antagonists; Drug Delivery Systems; Drug Design; Lactose; Methylcellulose; Metoclopramide; Oxazines; Permeability; Sclerosing Solutions

2001
Evaluation of stereoselective dissolution of racemic salbutamol matrices prepared with commonly used excipients and 1H-NMR study.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:5

    Topics: Adrenergic beta-Agonists; Albumins; Albuterol; Cyclodextrins; Drug Delivery Systems; Excipients; Lactose; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Solubility; Tablets

2001
Design and evaluation of a two-layer floating tablet for gastric retention using cisapride as a model drug.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:5

    Topics: Body Fluids; Cisapride; Delayed-Action Preparations; Drug Compounding; Drug Design; Gastric Juice; Gastric Mucosa; Gastrointestinal Agents; In Vitro Techniques; Lactose; Methylcellulose; Oxazines; Sodium Bicarbonate; Solubility; Tablets, Enteric-Coated

2001
Passive targeting of doxorubicin with polymer coated liposomes in tumor bearing rats.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Area Under Curve; Carcinoma 256, Walker; Doxorubicin; Drug Carriers; Lactose; Liposomes; Male; Methylcellulose; Neoplasm Transplantation; Oxazines; Particle Size; Polyvinyl Alcohol; Rats; Rats, Wistar

2001
Controlled and complete release of a model poorly water-soluble drug, prednisolone, from hydroxypropyl methylcellulose matrix tablets using (SBE)(7m)-beta-cyclodextrin as a solubilizing agent.
    Journal of pharmaceutical sciences, 2001, Volume: 90, Issue:7

    Topics: beta-Cyclodextrins; Cyclodextrins; Lactose; Methylcellulose; Oxazines; Prednisolone; Solubility; Tablets; X-Ray Diffraction

2001
Investigation of the influence of mean HPMC particle size and number of polymer particles on the release of aspirin from swellable hydrophilic matrix tablets.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, Sep-11, Volume: 76, Issue:1-2

    Topics: Aspirin; Lactose; Methylcellulose; Oxazines; Particle Size; Solubility; Tablets

2001
Effect of nicotinamide on the properties of aqueous HPMC solutions.
    International journal of pharmaceutics, 2001, Sep-11, Volume: 226, Issue:1-2

    Topics: Drug Storage; Gels; Lactose; Methylcellulose; Niacinamide; Oxazines; Solutions; Technology, Pharmaceutical; Temperature; Viscosity

2001
Biphasic drug release: the permeability of films containing pectin, chitosan and HPMC.
    International journal of pharmaceutics, 2001, Sep-11, Volume: 226, Issue:1-2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antidiarrheals; Chitin; Chitosan; Dosage Forms; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Oxazines; Pectins

2001
Development of a mucoadhesive dosage form for vaginal administration.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:6

    Topics: Administration, Intravaginal; Antifungal Agents; Body Fluids; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Clotrimazole; Diffusion; Female; Humans; Hyaluronic Acid; Lactose; Methylcellulose; Oxazines; Particle Size; Tissue Adhesives; Vagina

2001
A new drug delivery system using plasma-irradiated pharmaceutical aids. IX. Controlled-release of theophylline from double-compressed tablet composed of cellulose derivatives as wall material.
    Chemical & pharmaceutical bulletin, 2001, Volume: 49, Issue:12

    Topics: Argon; Drug Compounding; Drug Delivery Systems; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Pressure; Solubility; Spectrometry, Mass, Electrospray Ionization; Tablets; Theophylline

2001
In vitro evaluation of pectin-HPMC compression coated 5-aminosalicylic acid tablets for colonic delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2002, Volume: 53, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Colon; Compressive Strength; Drug Delivery Systems; Drug Evaluation, Preclinical; Lactose; Mesalamine; Methylcellulose; Oxazines; Pectins; Solubility; Tablets, Enteric-Coated

2002
Modulation of active pharmaceutical material release from a novel 'tablet in capsule system' containing an effervescent blend.
    Journal of controlled release : official journal of the Controlled Release Society, 2002, Feb-19, Volume: 79, Issue:1-3

    Topics: Capsules; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Drug Delivery Systems; Galactans; Lactose; Mannans; Methylcellulose; Oxazines; Plant Gums; Powders; Tablets

2002
Physical stability of redispersible dry emulsions containing amorphous sucrose.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2002, Volume: 53, Issue:2

    Topics: Chemistry, Pharmaceutical; Desiccation; Drug Stability; Emulsions; Lactose; Methylcellulose; Oxazines; Powders; Sucrose

2002
Studies on solubility and hypoglycemic activity of gliclazide beta-cyclodextrin-hydroxypropylmethylcellulose complexes.
    Die Pharmazie, 2002, Volume: 57, Issue:3

    Topics: Animals; Area Under Curve; beta-Cyclodextrins; Biological Availability; Blood Glucose; Crystallography, X-Ray; Cyclodextrins; Drug Compounding; Excipients; Gliclazide; Hypoglycemic Agents; Lactose; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Rats; Solubility; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Sterilization

2002
Release of ketoprofen enantiomers from HPMC K100M matrices--diffusion studies.
    International journal of pharmaceutics, 2002, Jun-04, Volume: 239, Issue:1-2

    Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Biopharmaceutics; Buffers; Delayed-Action Preparations; Diffusion; Excipients; Gels; Hydrogen-Ion Concentration; Ketoprofen; Kinetics; Lactose; Methylcellulose; Oxazines; Stereoisomerism; Tablets

2002
A local delivery system for fentanyl based on biodegradable poly(L-lactide-co-glycolide) oligomer.
    International journal of pharmaceutics, 2002, Jun-04, Volume: 239, Issue:1-2

    Topics: Analgesics, Opioid; Biocompatible Materials; Calorimetry, Differential Scanning; Chromatography, Gas; Crystallography, X-Ray; Drug Carriers; Fentanyl; Kinetics; Lactic Acid; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Water

2002
The effect of controlled release tablet performance and hydrogel strength on in vitro/in vivo correlation.
    Pharmaceutical development and technology, 2002, Volume: 7, Issue:2

    Topics: Acrylic Resins; Animals; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dogs; Hydrogel, Polyethylene Glycol Dimethacrylate; Lactose; Male; Methylcellulose; Oxazines; Polyvinyls; Solubility; Tablets; Theophylline

2002
Investigation of excipient type and level on drug release from controlled release tablets containing HPMC.
    Pharmaceutical development and technology, 2002, Volume: 7, Issue:2

    Topics: Alprazolam; Chemistry, Pharmaceutical; Delayed-Action Preparations; Excipients; Kinetics; Lactose; Mathematics; Methylcellulose; Models, Chemical; Oxazines; Solubility; Tablets

2002
Characterization of nifedipine solid dispersions.
    International journal of pharmaceutics, 2002, Aug-21, Volume: 242, Issue:1-2

    Topics: Administration, Sublingual; Calcium Channel Blockers; Crystallography, X-Ray; Differential Thermal Analysis; Excipients; Lactose; Methylcellulose; Nifedipine; Oxazines; Solubility; Spectroscopy, Fourier Transform Infrared

2002
Caffeine microparticles for nasal administration obtained by spray drying.
    International journal of pharmaceutics, 2002, Aug-21, Volume: 242, Issue:1-2

    Topics: Administration, Intranasal; Caffeine; Central Nervous System Stimulants; Drug Compounding; Excipients; Lactose; Mannitol; Methylcellulose; Microscopy, Electron, Scanning; Microspheres; Oxazines; Particle Size; Pharmaceutical Vehicles; Polyethylene Glycols; Powders

2002
The effect of viscosity on the perception of flavour.
    Chemical senses, 2002, Volume: 27, Issue:7

    Topics: Benzaldehydes; Dose-Response Relationship, Drug; Flavoring Agents; Gas Chromatography-Mass Spectrometry; Humans; Lactose; Methylcellulose; Models, Psychological; Oxazines; Perception; Solutions; Sucrose; Taste; Viscosity; Volatilization

2002
Effect of formulation variables on the floating properties of gastric floating drug delivery system.
    Drug development and industrial pharmacy, 2002, Volume: 28, Issue:7

    Topics: Acrylic Resins; Analysis of Variance; Chemistry, Pharmaceutical; Drug Delivery Systems; Kinetics; Lactose; Methylcellulose; Oxazines; Polyvinyls

2002
Characterization of a female controlled drug delivery system for microbicides.
    Contraception, 2002, Volume: 66, Issue:4

    Topics: Acrylates; Administration, Intravaginal; Animals; Anti-Infective Agents; Biocompatible Materials; Cervix Mucus; Drug Delivery Systems; Female; Gels; Humans; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Mucins; Oxazines; Rats; Solutions; Surface Tension; Viscosity

2002
Gentamicin release from modified acrylic bone cements with lactose and hydroxypropylmethylcellulose.
    Biomaterials, 2003, Volume: 24, Issue:1

    Topics: Anti-Bacterial Agents; Bone Cements; Delayed-Action Preparations; Drug Implants; Gentamicins; Humans; In Vitro Techniques; Lactose; Materials Testing; Methylcellulose; Microscopy, Electron, Scanning; Osteomyelitis; Oxazines; Polymethyl Methacrylate

2003
Influence of enteric citric acid on the release profile of 4-aminopyridine from HPMC matrix tablets.
    International journal of pharmaceutics, 2003, Jan-30, Volume: 251, Issue:1-2

    Topics: 4-Aminopyridine; Citric Acid; Lactose; Methylcellulose; Oxazines; Solubility; Tablets, Enteric-Coated

2003
[Preparation of buspirone hydrochloride buccal adhesive tablet and study on its drug release mechanism].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:8

    Topics: Acrylic Resins; Adhesiveness; Administration, Buccal; Anti-Anxiety Agents; Buspirone; Delayed-Action Preparations; Drug Carriers; Hardness; Lactose; Methylcellulose; Oxazines; Polyvinyls; Tablets; Technology, Pharmaceutical

2002
[Studies on heart-protecting musk pH-dependent gradient-release pellets].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:10

    Topics: Adult; Camphanes; Delayed-Action Preparations; Drug Combinations; Drugs, Chinese Herbal; Fatty Acids, Monounsaturated; Gastrointestinal Transit; Ginsenosides; Humans; Hydrogen-Ion Concentration; Lactose; Male; Materia Medica; Methylcellulose; Oxazines; Polymethacrylic Acids; Random Allocation

2002
[Preparation of diltiazem hydrochloride delayed-onset, sustained release tablet].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:9

    Topics: Cellulose; Delayed-Action Preparations; Diltiazem; Lactose; Methylcellulose; Oxazines; Polyvinyls; Pyrrolidinones; Tablets; Technology, Pharmaceutical; Viscosity

2002
[Preparation and in vitro release of tetramethylpyrazine phosphate pulsincap capsule controlled by an erodible plug].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:9

    Topics: Calcium Channel Blockers; Capsules; Delayed-Action Preparations; Drug Delivery Systems; Lactose; Methylcellulose; Oxazines; Pyrazines; Technology, Pharmaceutical

2002
[Application of an artificial neural network in the design of sustained-release dosage forms].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2001, Volume: 36, Issue:9

    Topics: Delayed-Action Preparations; Dextrans; Diltiazem; Drug Design; Isoniazid; Lactose; Methylcellulose; Neural Networks, Computer; Oxazines; Ranitidine; Solubility; Tablets

2001
[Improving bioavailability of naftopidil by using bioadhesion in dogs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2001, Volume: 36, Issue:5

    Topics: Acrylates; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Biological Availability; Capsules; Chemistry, Pharmaceutical; Dogs; Drug Carriers; Drug Delivery Systems; Lactose; Male; Methylcellulose; Naphthalenes; Oxazines; Piperazines; Rats

2001
Polymethacrylate salts as new low-swellable mucoadhesive materials.
    Journal of controlled release : official journal of the Controlled Release Society, 2003, Feb-14, Volume: 88, Issue:1

    Topics: Algorithms; Calorimetry, Differential Scanning; Dosage Forms; Lactose; Methylcellulose; Mucous Membrane; Oxazines; Polymethacrylic Acids; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Thermogravimetry; Tissue Adhesives

2003
Endotoxins in ophthalmic viscosurgical devices.
    European journal of ophthalmology, 2003, Volume: 13, Issue:2

    Topics: Endophthalmitis; Endotoxins; Gram-Negative Bacteria; Humans; Hyaluronic Acid; Lactose; Limulus Test; Methylcellulose; Ophthalmologic Surgical Procedures; Oxazines; Reproducibility of Results; Sensitivity and Specificity

2003
Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of celecoxib through human skin.
    Die Pharmazie, 2003, Volume: 58, Issue:5

    Topics: Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Emulsions; Gels; Humans; In Vitro Techniques; Isoenzymes; Lactose; Membrane Proteins; Methylcellulose; Ointments; Oxazines; Pharmaceutical Vehicles; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Skin Absorption; Solubility; Spectrophotometry, Ultraviolet; Sulfonamides

2003
Effect of carvone on the permeation of nimodipine from a membrane-moderated transdermal therapeutic system.
    Die Pharmazie, 2003, Volume: 58, Issue:8

    Topics: Administration, Cutaneous; Algorithms; Animals; Biological Availability; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclohexane Monoterpenes; Excipients; Gels; Humans; In Vitro Techniques; Lactose; Male; Membranes, Artificial; Methylcellulose; Monoterpenes; Nimodipine; Oxazines; Permeability; Polyvinyls; Rats; Skin Absorption; Spectrophotometry, Ultraviolet; Tablets; Terpenes

2003
Rapid separation and laser-induced fluorescence detection of mutated DNA by capillary electrophoresis in a self-coating, low-viscosity polymer matrix.
    Electrophoresis, 2003, Volume: 24, Issue:18

    Topics: Boric Acids; DNA; Electrophoresis, Capillary; Endonucleases; Fluorescent Dyes; Hydrogen-Ion Concentration; Lactose; Lasers; Mannitol; Methylcellulose; Oxazines; Point Mutation; Polymers; Reproducibility of Results; Surface Properties; Time Factors

2003
Modified release bi-layered tablet of melatonin using beta-cyclodextrin.
    Die Pharmazie, 2003, Volume: 58, Issue:9

    Topics: Acrylic Resins; Antioxidants; beta-Cyclodextrins; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cyclodextrins; Delayed-Action Preparations; Drug Stability; Excipients; Kinetics; Lactose; Melatonin; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Polyvinyls; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets

2003
Effect of curing conditions and plasticizer level on the release of highly lipophilic drug from coated multiparticulate drug delivery system.
    Pharmaceutical development and technology, 2003, Volume: 8, Issue:4

    Topics: Acrylic Resins; Biological Availability; Bumetanide; Chemistry, Pharmaceutical; Citrates; Drug Delivery Systems; Drug Storage; Lactose; Methylcellulose; Oxazines; Plasticizers; Solubility; Temperature; Time Factors

2003
[Release of diltiazem chloride and ibuprofen from hydrophilic matrix tablets].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2003, Volume: 52, Issue:6

    Topics: Cardiovascular Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Ibuprofen; Lactose; Methylcellulose; Oxazines; Solubility; Tablets

2003
Gamma scintigraphic evaluation of film-coated tablets intended for colonic or biphasic release.
    International journal of pharmaceutics, 2004, Feb-11, Volume: 270, Issue:1-2

    Topics: Acetaminophen; Administration, Oral; Adult; Chitin; Chitosan; Colon; Delayed-Action Preparations; Drug Stability; Gastric Emptying; Gastrointestinal Transit; Humans; Lactose; Male; Methylcellulose; Oxazines; Pectins; Radionuclide Imaging; Tablets, Enteric-Coated; Time Factors

2004
Method to recover a lipophilic drug from hydroxypropyl methylcellulose matrix tablets.
    AAPS PharmSciTech, 2001, Jun-09, Volume: 2, Issue:2

    Topics: Alprazolam; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Excipients; Lactose; Methylcellulose; Molecular Weight; Oxazines; Polymers; Solubility; Tablets; Viscosity

2001
Hot-melt extruded ethylcellulose cylinders containing a HPMC-Gelucire core for sustained drug delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2004, Feb-10, Volume: 94, Issue:2-3

    Topics: Cellulose; Drug Delivery Systems; Lactose; Methylcellulose; Oxazines; Polyethylene Glycols

2004
Development and evaluation of buccoadhesive propranolol hydrochloride tablet formulations: effect of fillers.
    Farmaco (Societa chimica italiana : 1989), 2004, Volume: 59, Issue:2

    Topics: Acrylic Resins; Adhesives; Adrenergic beta-Antagonists; Algorithms; Chemistry, Pharmaceutical; Delayed-Action Preparations; Excipients; Kinetics; Lactose; Methylcellulose; Mouth Mucosa; Nephelometry and Turbidimetry; Oxazines; Propranolol; Solubility; Tablets

2004
Prediction of drug release from HPMC matrices: effect of physicochemical properties of drug and polymer concentration.
    Journal of controlled release : official journal of the Controlled Release Society, 2004, Mar-05, Volume: 95, Issue:2

    Topics: Algorithms; Chemical Phenomena; Chemistry, Physical; Delayed-Action Preparations; Drug Compounding; Excipients; Lactose; Methylcellulose; Oxazines; Pharmaceutical Preparations; Polymers; Regression Analysis; Solubility; Tablets

2004
Penetration-enhancing effect of ethanol-water solvent system and ethanolic solution of carvone on transdermal permeability of nimodipine from HPMC gel across rat abdominal skin.
    Pharmaceutical development and technology, 2004, Volume: 9, Issue:1

    Topics: Abdomen; Administration, Cutaneous; Animals; Cyclohexane Monoterpenes; Ethanol; Gels; In Vitro Techniques; Lactose; Male; Methylcellulose; Monoterpenes; Nimodipine; Oxazines; Permeability; Rats; Skin; Solvents; Terpenes; Water

2004
Evaluation of novel one-step dry-coated tablets as a platform for delayed-release tablets.
    Journal of controlled release : official journal of the Controlled Release Society, 2004, Feb-20, Volume: 95, Issue:1

    Topics: Acetaminophen; Algorithms; Analgesics, Non-Narcotic; Delayed-Action Preparations; Drug Compounding; Drug Industry; Kinetics; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Pressure; Solubility; Surface Properties; Tablets; Tensile Strength

2004
Evaluation of ophthalmic suspensions using surface tension.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2004, Volume: 57, Issue:2

    Topics: Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorometholone; Indomethacin; Lactose; Methylcellulose; Ophthalmic Solutions; Oxazines; Pharmaceutical Solutions; Surface Tension

2004
Oxidative tissue damage after phacoemulsification: influence of ophthalmic viscosurgical devices.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:2

    Topics: Aged; Aqueous Humor; Free Radical Scavengers; Free Radicals; Humans; Hyaluronic Acid; Lactose; Lipid Peroxidation; Lipid Peroxides; Methylcellulose; Oxazines; Oxidative Stress; Phacoemulsification; Postoperative Complications; Thiobarbituric Acid Reactive Substances

2004
Alternative method for enteric coating of HPMC capsules resulting in ready-to-use enteric-coated capsules.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2004, Volume: 21, Issue:5

    Topics: Capsules; Lactose; Methylcellulose; Oxazines; Polymethacrylic Acids; Tablets, Enteric-Coated; Technology, Pharmaceutical

2004
The effect of wet granulation on the erosion behaviour of an HPMC-lactose tablet, used as a rate-controlling component in a pulsatile drug delivery capsule formulation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2004, Volume: 57, Issue:3

    Topics: Capsules; Delayed-Action Preparations; Drug Delivery Systems; Lactose; Methylcellulose; Oxazines; Rheology; Tablets; Technology, Pharmaceutical

2004
A study of phase separation in peptide-loaded HPMC films using T(zero)-modulated temperature DSC, atomic force microscopy, and scanning electron microscopy.
    Journal of pharmaceutical sciences, 2004, Volume: 93, Issue:7

    Topics: Calorimetry, Differential Scanning; Lactose; Methylcellulose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Oxazines; Peptides; Temperature

2004
The use of polymer-based electrospun nanofibers containing amorphous drug dispersions for the delivery of poorly water-soluble pharmaceuticals.
    Die Pharmazie, 2004, Volume: 59, Issue:5

    Topics: Antifungal Agents; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Drug Delivery Systems; Itraconazole; Lactose; Methylcellulose; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanotechnology; Oxazines; Pharmaceutical Preparations; Polymers; Solubility

2004
Different HPMC viscosity grades as coating agents for an oral time and/or site-controlled delivery system: a study on process parameters and in vitro performances.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2004, Volume: 22, Issue:5

    Topics: Administration, Oral; Coated Materials, Biocompatible; Delayed-Action Preparations; Lactose; Methylcellulose; Oxazines; Viscosity

2004
Therapeutic efficacy of "nubiotics" against burn wound infection by Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:8

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Burns; Ciprofloxacin; Drug Compounding; Excipients; Female; Lactose; Liposomes; Methylcellulose; Mice; Mice, Inbred BALB C; Nucleotides; Oxazines; Pseudomonas Infections; Survival Analysis; Wound Infection

2004
Effects of intrinsic variables on release of sodium dodecyl sulfate from a female controlled drug delivery system.
    International journal of pharmaceutics, 2004, Sep-10, Volume: 282, Issue:1-2

    Topics: Acrylic Resins; Administration, Intravaginal; Algorithms; Anti-Infective Agents; Buffers; Diffusion; Drug Delivery Systems; Excipients; Female; Humans; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Oxazines; Papillomaviridae; Polyvinyls; Sodium Dodecyl Sulfate

2004
[Description of the release of sodium ferulate from hydroxypropyl methylcellulose based matrix tablets in vitro].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:5

    Topics: Chemistry, Pharmaceutical; Coumaric Acids; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Delivery Systems; Kinetics; Lactose; Methylcellulose; Oxazines; Solubility; Tablets

2004
A predictive model for the release of slightly water-soluble drugs from HPMC matrices.
    Die Pharmazie, 2004, Volume: 59, Issue:8

    Topics: Delayed-Action Preparations; Diffusion; Excipients; Kinetics; Lactose; Methylcellulose; Models, Chemical; Molecular Weight; Oxazines; Predictive Value of Tests; Solubility; Tablets; Water

2004
Once-daily propranolol extended-release tablet dosage form: formulation design and in vitro/in vivo investigation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2004, Volume: 58, Issue:3

    Topics: Administration, Oral; Animals; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dogs; Dosage Forms; Drug Administration Schedule; Drug Design; Lactose; Male; Methylcellulose; Oxazines; Propranolol; Tablets

2004
Evaluation of khaya gum as a directly compressible matrix system for controlled release.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:11

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Excipients; Indomethacin; Lactose; Meliaceae; Methylcellulose; Oxazines; Plant Preparations; Solubility; Tablets

2004
Drug release from tableted wet granulations comprising cellulosic (HPMC or HPC) and hydrophobic component.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2005, Volume: 59, Issue:1

    Topics: Cellulose; Hydrophobic and Hydrophilic Interactions; Lactose; Methylcellulose; Oxazines; Solubility; Tablets

2005
Characterization of cellulosic hot-melt extruded films containing lidocaine.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2005, Volume: 59, Issue:1

    Topics: Cellulose; Chemistry, Pharmaceutical; Lactose; Lidocaine; Methylcellulose; Oxazines

2005
Preparation and evaluation of pH-dependent gradient-release pellets for TCM.
    Drug development and industrial pharmacy, 2004, Volume: 30, Issue:10

    Topics: Animals; Capsules; Chemistry, Pharmaceutical; China; Cinnamates; Complex Mixtures; Delayed-Action Preparations; Drug Compounding; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Lactose; Male; Medicine, Chinese Traditional; Methylcellulose; Oxazines; Solubility; Technology, Pharmaceutical

2004
[Effect of the sustained release excipients on the release rate of ginsenoside Rg1 and ginsenoside Rb1 in sustained-release tablet of Panax notoginsenosides].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:10

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drugs, Chinese Herbal; Excipients; Ginsenosides; Lactose; Methylcellulose; Oxazines; Panax; Plants, Medicinal; Tablets

2004
[Rapid analysis of genetically modified soybean by a duplex PCR-capillary electrophoresis system with laser-induced fluorescence detection].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2005, Volume: 36, Issue:1

    Topics: DNA, Plant; Electrophoresis, Capillary; Glycine max; Lactose; Methylcellulose; Oxazines; Plants, Genetically Modified; Polymerase Chain Reaction

2005
Erosion characteristics of an erodible tablet incorporated in a time-delayed capsule device.
    Drug development and industrial pharmacy, 2005, Volume: 31, Issue:1

    Topics: Adrenergic beta-Antagonists; Calcium Phosphates; Calcium Sulfate; Capsules; Delayed-Action Preparations; Drug Delivery Systems; Excipients; Lactose; Methylcellulose; Oxazines; Propranolol; Solubility; Tablets

2005
Investigation of the effect of various shellac coating compositions containing different water-soluble polymers on in vitro drug release.
    Drug development and industrial pharmacy, 2005, Volume: 31, Issue:1

    Topics: Acrylic Resins; Delayed-Action Preparations; Drug Stability; Excipients; Lactose; Methylcellulose; Microscopy, Confocal; Oxazines; Polyvinyl Alcohol; Resins, Plant; Solubility; Surface Properties; Tablets, Enteric-Coated

2005
Asymmetric membrane capsules for delivery of poorly water-soluble drugs by osmotic effects.
    International journal of pharmaceutics, 2005, Jun-13, Volume: 297, Issue:1-2

    Topics: Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Delivery Systems; Lactose; Membranes, Artificial; Methylcellulose; Microscopy, Electron, Scanning; Osmosis; Oxazines; Pharmaceutical Preparations; Polysorbates; Sodium Dodecyl Sulfate; Solubility; Spectrophotometry, Ultraviolet; Surface-Active Agents

2005
The diffusion of latex nanospheres and the effective (microscopic) viscosity of HPMC gels.
    International journal of pharmaceutics, 2005, Jul-25, Volume: 298, Issue:2

    Topics: Diffusion; Excipients; Gels; Lactose; Latex; Light; Methylcellulose; Nanotubes; Oxazines; Scattering, Radiation; Viscosity

2005
Modulation of Tenoxicam release from hydrophilic matrix: modulator membrane versus rate-controlling membrane.
    Chemical & pharmaceutical bulletin, 2005, Volume: 53, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry, Physical; Drug Carriers; Drug Delivery Systems; Kinetics; Lactose; Membranes, Artificial; Methylcellulose; Microscopy, Electron, Scanning; Oxazines; Piroxicam; Surface Properties

2005
In vivo evaluation of nicotine lyophilised nasal insert in sheep.
    International journal of pharmaceutics, 2005, Nov-04, Volume: 304, Issue:1-2

    Topics: Administration, Intranasal; Adsorption; Aerosols; Animals; Biological Availability; Delayed-Action Preparations; Excipients; Freeze Drying; Gels; Injections, Intravenous; Lactose; Methylcellulose; Nasal Mucosa; Nicotine; Oxazines; Porosity; Powders; Random Allocation; Sheep; Solubility

2005
Drug nanoparticle formation from drug/HPMC/SDS ternary ground mixtures.
    Die Pharmazie, 2006, Volume: 61, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Drug Stability; Flurbiprofen; Lactose; Methylcellulose; Nanostructures; Oxazines; Particle Size; Pharmaceutical Preparations; Sodium Dodecyl Sulfate; Spectrophotometry, Infrared; X-Ray Diffraction

2006