lactic acid and nad

lactic acid has been researched along with nad in 470 studies

Research

Studies (470)

TimeframeStudies, this research(%)All Research%
pre-1990111 (23.62)18.7374
1990's87 (18.51)18.2507
2000's95 (20.21)29.6817
2010's141 (30.00)24.3611
2020's36 (7.66)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Banquells, M; Drobnic, F; Galilea, PA; Pons, V; Rodríguez, FA1
McLellan, AC; Phillips, SA; Thornalley, PJ1
Onigbinde, TA; Simmons, MJ; Wong, SS; Wu, AH; Wu, YS1
Berry, MN; Gregory, RB; Grivell, AR; Phillips, JW; Wallace, PG1
Aw, TY; Jones, DP; Kowalski, DP; Park, Y1
Anderson, VE; LaReau, RD2
Klions, HA; Kramer, DJ; Nemoto, EM; Schlichtig, R1
Chang, TM; Gu, KF1
Chang, GG; Chiou, SH; Huang, SM; Lee, HJ1
Carriero, D; Piomelli, S; Seaman, C; Tilton, WM1
Goto, H; Hirota, T; Kondoh, Y; Nakata, K; Nose, Y; Ogawa, H; Ohmori, S; Tsuboi, S; Tsuyama, K; Yano, Y1
Felipo, V; Grau, E; Grisolía, S; Kosenko, E; Miñana, MD1
Opie, LH1
Chang, GG; Chiou, SH; Huang, SM1
Bohnensack, R; Fritz, S1
Alcain, FJ; Buron, MI; Navas, P; Villalba, JM1
Marcy, VR; Sims, RE; Welsh, FA1
Cannon, PJ; Keller, AM1
Javed, MH1
de Groot, CJ; Feller, N; Wanders, RJ; Wijburg, FA1
Argilés, JM; López-Soriano, FJ1
Dargel, R; Dietrich, N; Haufe, CC; Schulze, HP1
Bovara, R; Carrea, G; Ferri, E; Ghini, S; Girotti, S; Grigolo, B; Motta, R; Petilino, R; Roda, A1
Asouzu, MU; Ho, MH; Nonidez, WK1
Chang, GG; Chiou, SH; Lee, HJ1
Clegg, JS; Jackson, SA1
Fernandez-Romero, JM; Luque de Castro, MD; Valcarcel, M1
Ghani, QP; Hunt, TK; Hussain, MZ1
Graham, TE; Saltin, B1
Kleinholz, M; Myers, RE; Wagner, KR1
Heikkila, RE; Nicklas, WJ; Ofori, S1
Erecinska, M; Meglasson, MD; Nelson, D; Smith, KM1
Bhattacharyya, A; Hoskins, DD; Vijayaraghavan, S1
Matsuno, T1
Pall, ML; Robertson, CK1
Blachier, F; Malaisse, WJ; Sener, A1
Bhatnagar, RS; Hunt, TK; Hussain, MZ1
Aprille, JR; Tullson, PC1
Laustiola, K1
Lardy, HA; Warnette-Hammond, ME1
Baudet, A; Goodyer, P; Robinson, BH; Ward, J1
Marsac, C; Stansbie, D; Wallace, SJ1
Katz, A; Sahlin, K1
Chin, NW; Hitti, IF; Lanks, KW1
Clary, GL; Guynn, RW1
Dwyer, BE; Fujikawa, DG; Vannucci, RC; Wasterlain, CG1
Grunnet, N; Vind, C4
Medina, MA; Núñez de Castro, I; Sánchez-Jiménez, F; Segura, JA1
Cooper, GJ; Ferguson, LR; Roberton, AM1
Bachelard, HS; Cox, DW; Garofalo, O1
Kaneoka, T; Shimizu, H; Shirakawa, K; Taguchi, S1
Henriksson, J; Katz, A; Ren, JM; Sahlin, K1
Halestrap, AP; Pryor, HJ; Quinlan, PT; Smyth, JE1
Chan, AW; Klein, A; Malkin, A1
Kittlick, PD1
Kamiyama, Y; Koizumi, K; Morimoto, T; Nitta, N; Noguchi, M; Taki, Y; Tanaka, A; Ukikusa, M; Yamamoto, S; Yokoo, N1
Coleman, AE; Cooper, AJ; Lai, JC; Pulsinelli, WA1
Henriksson, J; Katz, A; Sahlin, K2
Kamiyama, Y; Noguchi, M; Ozawa, K; Shimahara, Y; Taki, Y; Tanaka, A1
Hjelle, JJ1
Brindle, KM; Campbell, ID; Simpson, RJ3
Chakraborty, J; Ryle, PR; Thomson, AD1
Fagan, JM; Tischler, ME2
Sestoft, L1
Cuezva, JM; Patel, MS1
Olson, MS; Steinhelper, ME1
Siemes, H1
Stern, A; Thornalley, PJ2
Clarke, AR; Hart, KW; Holbrook, JJ; Waldman, AD1
Babin, W; Kittlick, PD1
Haynes, RC; Sistare, FD2
Dóra, E2
Fieber, RS; Kellner, K; Marek, H1
Berry, MN; Chalmers, AH; Mazzachi, RD1
Heinle, H; Linke, AM1
Avi-Dor, Y; Diamant, P; Ravid, K1
Amos, H; Lively, MK; Lombardi, D; Mandel, KG1
Bruno, R; Curto, M; Rinaudo, MT1
Duff, DA; Snell, K1
Karp, M; Laustiola, K; Metsä-Ketelä, T; Vapaatalo, H; Vuorinen, P1
Gorbach, ZV; Maglysh, SS; Ostrovskiĭ, IuM1
Laustiola, K; Metsä-Ketelä, T; Vuorinen, P1
Seitz, HK1
Barrett, J1
Kimura, RE; Thulin, G; Warshaw, JB1
Eckfeldt, JH; Kershaw, MJ; Lewis, LA1
Buxton, DB; Hanahan, DJ; Olson, MS1
Litwińska, D; Popinigis, J; Szczesna-Kaczmarek, A1
Fiolitakis, E; Kula, MR; Wandrey, C; Wichmann, U1
Araki, R; Tamura, M; Yamazaki, I1
Busto, F; de Arriaga, D; Soler, J1
Bowen, WH; Curtis, MA; Robrish, SA; Sharer, SA1
Guynn, RW; Kuo, YJ; Shanbour, LL1
Hosotani, K; Kitaoka, S; Yokota, A1
Caspritz, G; Radler, F1
Caparrotta, L; Fassina, G; Scotini, E; Tessari, F1
Ayromlooi, J; Das, DK; Neogi, A1
Muir, LA; White, LS; Yang, YT1
McKeehan, KA; McKeehan, WL1
Brindle, KM; Brown, FF; Campbell, ID; Foxall, DL; Simpson, RJ1
Nicolau, J; Sassaki, KT1
Maughan, RJ1
Jones, DP; Kennedy, FG1
Brandt, RB1
Kovách, AG; Rubányi, G; Tóth, A1
Pretorius, PJ; Snyman, LD; Van Der Walt, JJ1
Degrel, I; Molnár, L; Szabó, E1
Momsen, G1
Butterworth, PJ; Jünemann, S; Wrigglesworth, JM1
Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T1
Khan, S; Niknahad, H; O'Brien, PJ1
Kanno, T; Maekawa, M1
Catelloni, F; Fontaine, E; Keriel, C; Leverve, XM; Rigoulet, M; Sibille, B1
Javed, MH; Qureshi, MA; Waqar, MA1
Bernocchi, P; Cargnoni, A; Ceconi, C; Curello, S; Ferrari, R1
Asahina, T; Harada, N; Ikebuchi, M; Kashiwagi, A; Kikkawa, R; Nishio, Y; Saeki, Y; Shigeta, Y; Takagi, Y; Tanaka, Y1
Gurevich, P; Oren, A1
Hussain, AN; Ishaq, M; Javed, MU; Waqar, MA; Yousuf, FA1
Burstein, C; Geloso-Meyer, A; Haouz, A1
Flint, HJ; Gilmour, M; Mitchell, WJ1
Raj, RK; Sivan, VM1
Chagoya de Sánchez, V; Díaz-Muñoz, M; Hernández-Muñoz, R1
Griffiths, JR; Howe, FA; Jeong, KS; Rodrigues, L; Stubbs, M; Veech, RL; Wang, J1
Juurlink, BH1
Bachelard, HS; Badar-Goffer, RS; Ben-Yoseph, O; Morris, PG1
Miles, RJ; Taylor, RR; Varsani, H1
Kobayashi, K; Nakatani, T; Spolter, L1
de Graef, MR; Neijssel, OM; Snoep, JL; Teixeira de Mattos, MJ1
Bülow, L; Carlsson, H; Prachayasittikul, V1
Lubbers, F; Neijssel, OM; Snoep, JL; Teixeira de Mattos, MJ; van Bommel, M1
Crabb, DW; Sidhu, R1
Feng, JJ; Hunt, TK; Hussain, MZ; Scheuenstuhl, H; Zabel, DD1
Bracht, A; Constantin, J; Ishii-Iwamoto, EL; Nascimento, EA; Salgueiro-Pagadigorria, CL1
Dowdy, YG; Eder, AF; Gardiner, JA; Shaw, LM; Wolf, BA1
Gleitz, J; Peters, T; Tosch, C1
Bernocchi, P; Cargnoni, A; Ceconi, C; Curello, S; Ferrari, R; Pasini, E; Ruigrok, TJ1
Diez-Gonzalez, F; Hunter, JB; Russell, JB1
Bazotte, RB; Brunaldi, K; Ferraz, M; Oliveira, CE1
Alegre, J; Martí, R; Pascual, C; Segura, RM; Suriñach, JM; Varela, E1
Clarke, AR; Dewar, V; Holbrook, JJ; Sessions, RB1
Cocaign-Bousquet, M; Garrigues, C; Lindley, ND; Loubiere, P1
Asahina, T; Harada, N; Hidaka, H; Ikebuchi, M; Kashiwagi, A; Kikkawa, R; Nishio, Y; Obata, T; Saeki, Y; Takahara, N; Taki, H; Tanaka, Y1
Bünger, R; Lasley, RD; Martin, BJ; Mentzer, RM; Valdivia, HH1
Baio, DL; Cunningham, CC; Czyz, CN; Ivester, P; Van Horn, CG1
Balle, BS; Poole, RK1
Deck, LM; Gomez, MS; Hunsaker, LA; Makler, MT; Piper, RC; Royer, RE; Vander Jagt, DL1
Adachi, T; Aikawa, N; Hori, S; Inoue, S; Miyazaki, K; Nakagawa, M; Nakazawa, H; Ogawa, S; Ohnishi, Y1
Guérin, M; Manon, S1
Adler, L; Ansell, R; Gustafsson, L; Larsson, C; Påhlman, IL; Rigoulet, M1
Coffe, V; Hernández-Muñoz, R; Salceda, R; Vilchis, C1
Gutheil, WG1
Moiseenok, AG; Omelyanchik, SN; Slyshenkov, VS; Trebukhina, RV; Wojtczak, L1
Devin, A; Espié, P; Leverve, X; Piquet, MA; Rigoulet, M; Sibille, B1
Chamblee, BB; Deck, LM; Hernandez, VM; Hunsaker, LA; Makler, MT; Malone, RR; Piper, RC; Royer, RE; Torres, JE; Vander Jagt, DL1
Bringer-Meyer, S; Galinina, N; Kalnenieks, U; Poole, RK1
Fry, AJ; Leonida, MD; Sobolov, SB1
Bryła, J; Lietz, T; Rybka, J1
Iborra, JL; Manjón, A; Obón, JM1
Ewert, D; Mansfield, K; Ohyama, K; Rajpurohit, R; Shapiro, IM1
Joshi, NB; Kannurpatti, SS1
Clarke, AR; Dafforn, TR; Dempsey, CE; Eszes, CM; Hewitt, CO; Holbrook, JJ; Moreton, KM; Sessions, RB; Takei, J1
Gemeinhardt, H; Greulich, KO; Monajembashi, S; Nasanshargal, B; Schäfer, B; Uhl, V1
Holm, S; Möller, A; Ström, D1
Hugenholtz, J; Kleerebezem, M1
Ainscow, EK; Brand, MD2
Gelhaye, E; Guedon, E; Payot, S; Petitdemange, H1
Gardner, DK; Lane, M1
Alcaraz, G; Cachon, R; Diviès, C; Riondet, C; Waché, Y1
Cechowska-Pasko, M; Pałka, J1
Almeida, A; Bolaños, JP; Delgado-Esteban, M1
Barron, JT; Gu, L; Parrillo, JE1
Jones, AR; Piccolo, F1
Rupert, BE; Scholz, TD; Schutte, BC; Segar, JL1
Edwards, JS; McCulloch, A; Palsson, BO; Ramakrishna, R1
Bückmann, AF; Katz, E; Kharitonov, AB; Willner, I; Zayats, M1
Abbe, K; Takahashi, N; Takahashi-Abbe, S; Tamazawa, Y; Yamada, T1
Boyd, C; Cousins, K; Daya, S; Heron, P1
Lang, HJ; Obrosova, IG; Stevens, MJ1
Akimoto, LS; Bazotte, RB; Lopes, G; Pedrinho, SR1
Chang, K; Ido, Y; Williamson, JR; Woolsey, TA1
Eiteman, MA; Sridhar, J1
Devin, A; Guérin, B; Leverve, X; Nogueira, V; Rigoulet, M1
Hunt, NH; Maitland, A; Rae, C; Sanni, LA; Stocker, R1
Bouzier-Sore, AK; Canioni, P; Merle, M1
Aitken, RJ; Fulton, N; Vernet, P; Wallace, C1
Duebener, LF; Hatsuoka, S; Jonas, RA; Menger, MD; Sakamoto, T; Schäfers, HJ; Stamm, C; Vollmar, B; Zurakowski, D1
Bongard, RD; Dawson, CA; Kettenhofen, NJ; Merker, MP; Okamoto, Y1
Hussian, ZM; Zhang, J1
Bartlett, PN; Cass, AE; Halliwell, CM; Simon, E; Toh, CS1
Allen, JC; Kahn, AM; Zhang, S1
Cabrera, ME; Saidel, GM; Salem, JE; Stanley, WC1
Bückmann, AF; Katz, E; Raitman, OA; Willner, I1
Dileme, FB; Lüthi-Peng, Q; Puhan, Z1
Chatham, JC1
Daniel, S; Eto, K; Iino, M; Izumi, K; Kadowaki, T; Kasai, H; Nemoto, T; Noda, M; Sharp, GW; Shen, LM; Takahashi, N; Tsubamoto, Y; Yamashita, S1
Metcalf, WW; van der Donk, WA; Vrtis, JM; White, AK1
Capacchione, J; Dubois, D; Karaian, J; Keneally, R; Mongan, PD; Sharma, P; West, S1
Ikeda, T; Kaneko, T; Kano, K; Taketomo, N; Yamazaki, S1
Alonso, JC; Fuentes, JM; González-Polo, RA; Rodríguez-Martín, A; Soler, G1
Blatter, LA; Kockskämper, J; Mejia-Alvarez, R; Zima, AV1
Gregory, JF; McMahon, RJ; Rathman, SC1
WIELAND, O1
HOLZER, H; SCHNEIDER, S1
DENSTEDT, OF; OTTOLENGHI, P1
FROMM, HJ1
LEUTS'KII, KM; LIVKE, VO1
GRAYMORE, C; TOWLSON, M1
FABRICANT, J; SMITH, SL; VANDEMARK, PJ1
GUENTHER, T; WENZEL, M1
GREENE, NM; TALNER, NS1
NIEMI, M; SALENIUS, P1
PASCAL, MC; PICHINOTY, F1
HAAF, AS; WITTENBERGER, CL1
NAGARAJAN, K1
BROHEE, H; WHITFIELD, JF; YOUDALE, T1
CATO, EP; MOORE, WE1
ABABEI, L; RAPOPORT, S1
Asimakis, GK; Chinkes, DL; Gore, DC; Hart, DW; Rinehart, AJ1
De Graaf, AA; Hamann, I; Richter, H; Unden, G1
Chaubey, A; Malhotra, BD; Pande, KK1
Chang, K; Ido, Y; Williamson, JR1
Elling, RA; Kavanagh, KL; Wilson, DK1
Kudej, RK; LaNoue, KF; Lewandowski, ED; O'Donnell, JM; Vatner, SF1
Carbajal, RC; Coffe, V; Salceda, R1
Bracht, A; Constantin, J; Gimenes, D; Lopez, CH; Suzuki-Kemmelmeier, F1
Becker, HD; Ghani, QP; Hunt, TK; Hussain, MZ; Wagner, S1
Abdo, WF; Bloem, BR; De Jong, D; Hendriks, JC; Horstink, MW; Kremer, BP; Verbeek, MM1
Cabrera, ME; Salem, JE; Stanley, WC1
Magistretti, PJ; Pellerin, L1
Fisher, PJ; Kasischke, KA; Vishwasrao, HD; Webb, WW; Zipfel, WR1
Comtat, M; Gros, P1
Caruso, LJ; Gabrielli, A; Marko, P1
Goffin, P; Hols, P; Kleerebezem, M; Lorquet, F1
Inui, M; Kawaguchi, H; Murakami, S; Okino, S; Vertès, AA; Yukawa, H1
Ido, Y; Kilo, C; Nyengaard, JR; Williamson, JR1
Ahmad, M; Arcuino, E; Oeckler, RA; Olson, SC; Wolin, MS1
Bratus', LV; Havenauskas, BL; Man'kovs'ka, IM; Nazarenko, AI; Nosar, VI1
Gygi, SP; Haas, W; Lerin, C; Puigserver, P; Rodgers, JT; Spiegelman, BM1
Antosiewicz, J; Falcioni, G; Fedeli, D; Gabbianelli, R; Olek, RA; Popinigis, J1
Aubert, A; Costalat, R1
Moriwaki, Y; Takahashi, S; Yamamoto, T1
Clark, JB; Duchen, MR; Heales, SJ; Hothersall, J; Jacobson, J1
Cabrera, ME; Saidel, GM; Stanley, WC; Yu, X; Zhou, L1
Aubert, A; Costalat, R; Magistretti, PJ; Pellerin, L1
Chuang, CK; Ho, SC; Hsieh, WS; Lin, DS; Lin, SP; Wang, TJ; Yeung, CY1
Bracht, A; Bracht, F; Constantin, J; Kelmer-Bracht, AM; Martins, AG1
Berkowitz, BA; Diederen, RM; Starnes, CA; Winkler, BS1
Kahn, AM; Yang, M1
Adriany, T; De Vuyst, L; Van der Meulen, R; Verbrugghe, K1
Feller, C; Grunow, M; Günther, R; Hofmann, HJ1
Jena, BK; Raj, CR1
Bergold, PJ; Gilbert, E; Ludvig, N; Tang, JM1
Furusaki, S; Hayashi, S; Honda, H; Kobayashi, T; Nakagawa, I; Okochi, M1
Kiran, MS; Kumar, VB; Sudhakaran, PR; Viji, RI1
Carroll, J; Duchen, MR; Dumollard, R; Ward, Z1
Bian, F; Cabrera, ME; Huang, H; Monika, DK; Sharma, N; Stanley, WC; Yuan, CL; Zhou, L1
Bolívar, F; Gosset, G; Martinez, A; Merino, E; Romero, S1
Sakurai, T; Takata, T; Wang, X; Yokono, K1
Atlante, A; Bobba, A; de Bari, L; Marra, E; Passarella, S1
Birkmayer, J; Komi, P; Mero, A; Raitanen, R1
Gatica, JE; Koppaka, SS; LaManna, JC1
Gao, XF; Ju, X; Li, YS; Wu, YF; Zhao, YY1
Bracht, A; Bracht, F; de Sá-Nakanishi, AB; Kelmer-Bracht, AM; Padilha, F; Yamamoto, NS1
Callender, R; Gulotta, M; Zhadin, N1
Bracht, A; Bracht, F; Broetto-Biazon, AC; Kangussu, MM; Kelmer-Bracht, AM; Padilha, F1
Cabrera, ME; Dash, RK; Kim, J; Li, Y; Saidel, GM1
Rahman, MA; Rahman, MM; Shiddiky, MJ; Shim, YB1
Hagopian, K; Ramsey, JJ; Weindruch, R1
Liu, W; Wang, P; Zhang, S1
Ma, C; Ma, Y; Qin, J; Sun, J; Tang, H; Wang, L; Wang, X; Xu, P; Yu, B; Zhao, B1
Al-Helal, M; Biagini, GA; Bray, PG; Fisher, N; Lian, LY; Roslaini, AM; Ward, SA1
Lin, Y; Mao, L; Su, L; Yu, P; Zhu, N1
Dai, R; Li, X; Liu, F; Zhu, J1
Guo, NN; Liu, DH; Liu, HJ; Ou, XJ; Xu, YZ; Zheng, ZM1
Feron, O1
de Groof, AJ; Fransen, JA; Oerlemans, F; Pluk, H; Smift, AL; te Lindert, MM; van Dommelen, MM; Wieringa, B; Willemse, M; Winer, M; Wu, M1
Brown, SA; Whiteley, M1
Antosiewicz, J; Borkowska, A; Herman-Antosiewicz, A; Kurono, Ch; Soji, T; Spodnik, JH; Teranishi, M; Wakabayashi, T; Woźniak, M1
Antonyuk, SV; Bessho, Y; Ellis, MJ; Hasnain, SS; Inoue, Y; Kuramitsu, S; Strange, RW; Yokoyama, S1
van Niel, EW; Willquist, K1
Chen, CS; Kulp, SK; Wei, S1
Atlante, A; de Bari, L; Passarella, S; Valenti, D1
Barstow, TJ; Houser, TA; Hunt, MC; Mohan, A; Muthukrishnan, S1
Li, CM; Yang, HB; Zheng, XT1
Cheng, SS; Freguia, S; Kano, K; Li, SL; Liu, SM; Shirai, O; Tsujimura, S1
Drago, GA; Hart, JP; Piano, M; Pittson, R; Serban, S1
Hirrlinger, J; Requardt, RP; Rillich, J; Wilhelm, F; Winkler, U1
El-Zahab, B; Liu, Y; Tong, X; Wang, P; Zhao, X1
Heo, SY; Hong, WK; Kim, CH; Kim, DH; Luo, LH; Oh, BR; Seo, JW; Seo, PS1
de Almeida, A; Giordano, AM; Godoy, MS; Nikel, PI; Pettinari, MJ1
Fujii, T; Kitazume, T; Masuo, S; Shimizu, M; Takaya, N; Terabayashi, Y1
Baek, JO; Heo, SY; Hong, WK; Kim, CH; Kim, DH; Luo, LH; Oh, BR; Seo, JW1
Dybala-Defratyka, A; Rohr, DR; Swiderek, K1
Chieppa, G; De Bari, L; Marra, E; Passarella, S1
Rawat, AK1
Agrawal, R; Mohan, J; Moudgal, RP; Pandey, NK; Sastry, KV; Saxena, VK; Shit, N; Singh, KB; Singh, RP1
Aw, TY; Circu, ML; Maloney, RE1
Ananyev, G; Bennette, N; Bryant, DA; Dismukes, GC; McNeely, K; Xu, Y1
Betti, L; Calvaresi, EC; Funel, N; Giacomelli, C; Giannaccini, G; Giovannetti, E; Granchi, C; Hergenrother, PJ; Lanza, M; León, LG; Lucacchini, A; Macchia, M; Martinelli, A; Minutolo, F; Palchaudhuri, R; Peters, GJ; Roy, S; Tuccinardi, T1
Anklin, C; Courdier Fruh, I; Dallmann, R; Erb, M; Gemperli, AC; Gueven, N; Haefeli, RH; Robay, D1
Gao, C; Li, F; Ma, C; Qin, J; Wang, K; Xu, P; Zhang, H; Zheng, Z1
Engel, PC; Guyonvarch, A; Maher, MA; Sharkey, MA1
Bracht, A; Itinose, AM; Marek, CB; Peralta, RM1
Borras, C; Gambini, J; Gomez-Cabrera, MC; Herranz, D; Lopez-Grueso, R; Martinez-Bello, VE; Pallardo, FV; Serrano, M; Tresguerres, JA; Valles, SL; Viña, J1
Byrne, ME; Chambers, RP; Eggert, MW1
Ingram, LO; Miller, EN; Shanmugam, KT; Wang, X; Yomano, LP; Zhang, X1
Chertov, AO; Couron, D; Holzhausen, L; Hurley, JB; Kuok, IT; Linton, JD; Parker, E; Sadilek, M; Sweet, IR1
Boggon, TJ; Chen, GZ; Chen, J; Chung, TW; Fan, J; Ge, Q; Gu, TL; Hitosugi, T; Kang, S; Khuri, FR; Lonial, S; Polakiewicz, RD; Xie, J1
Hu, Q; Jin, J; Loscalzo, J; Wang, X; Xu, L; Yang, Y; Yi, J; Yu, Z; Zhao, Y; Zhou, HM1
Chesney, J; Telang, S1
Banrezes, B; Cancela, J; Canon, E; Ozil, JP; Sainte-Beuve, T; Schultz, RM1
Hallaj, R; Salimi, A; Teymourian, H1
Catalanotti, C; Dubini, A; Grossman, AR; Magneschi, L; Mus, F; Perata, P; Posewitz, MC; Seibert, M; Subramanian, V; Yang, W1
Besser, S; Hirrlinger, J; Hirrlinger, PG; Requardt, RP; Wilhelm, F; Winkler, U1
Fukuda, J; Hatazawa, T; Kano, K; Sakai, H; Shirai, O; Tokita, Y; Tsujimura, S1
Itoh, M; Kaneko, YS; Kondo, K; Mori, K; Nagasaki, H; Nagatsu, T; Nakashima, A; Ota, A; Ota, M; Takayanagi, T1
Benard, G; Calvaruso, MA; de Groof, AJ; Forkink, M; Heeman, B; Koopman, WJ; Monge, C; Nijtmans, LG; Rodenburg, RJ; Roestenberg, P; Rossignol, R; Smeitink, JA; Swarts, HG; Valsecchi, F; van Emst-de Vries, SE; Wieringa, B; Willems, PH1
Choi, BY; Jang, BG; Kim, JH; Lee, MW; Sohn, M; Song, HK; Suh, SW; Won, SJ; Yoo, BH1
Guo, T; Hu, S; Kong, J; Zhang, C; Zhang, L1
Dai, C; Hu, X; Sun, F; Xie, J1
Dou, P; Gao, C; Jiang, T; Kong, J; Li, L; Ma, C; Xu, P1
Bhadhuri, G; Bhattacharya, B; Choudhuri, S; Chowdhury, IH; Dutta, D; Mandal, LK; Mukherjee, A; Paine, SK; Saha, A; Sen, A1
Attwell, D; Hall, CN; Howarth, C; Klein-Flügge, MC1
Guo, L; Nie, R; Tian, M; Wang, Y; Yang, L; Zhao, W1
Banerjee, N; Bhattacharyya, D1
Calbet, JA; Cusso, MR; Dorado, C; Guadalupe-Grau, A; Guerra, B; Guerrero, M; Morales-Alamo, D; Ponce-González, JG; Rodríguez-García, L; Santana, A1
Mannowetz, N; Wandernoth, PM; Wennemuth, G1
Corkey, BE; Shirihai, O1
Hertz, L; Li, B; Peng, L1
Costalat, R; Neves, A; Pellerin, L1
Bidart, GN; de Almeida, A; Méndez, BS; Nikel, PI; Ruiz, JA1
Kerr, AB; Larson, PE; Pauly, JM; Swisher, CL; Vigneron, DB1
Chorvat, D; Chorvatova, A; Elzwiei, F; Mateasik, A1
Hasegawa, S; Hiraga, K; Inui, M; Jojima, T; Natsuma, Y; Suda, M; Uematsu, K; Yukawa, H1
Calbet, JA; Cusso, R; Dorado, C; Guadalupe-Grau, A; Guerra, B; Guerrero, M; Morales-Alamo, D; Ponce-González, JG; Rodríguez-García, L; Santana, A1
Heo, SY; Kim, CH; Kim, DH; Luo, LH; Oh, BR; Seo, JW1
Attanasio, F; Buccione, R; Fransen, JA; Güneri, T; Haeger, A; Schwab, A; Stock, CM; van Horssen, R; Wieringa, B; Willemse, M1
Joseph, P; Mancini, RA; Ramanathan, R; Suman, SP1
Bench, G; Knaack, JL; Kulp, KS; Navid, A; Stewart, BJ1
Jacobs, RA; Lundby, C; Meinild, AK; Nordsborg, NB1
Li, Y; Liang, H; Sun, L; Wu, J; Yuan, Q1
Furusawa, C; Hirasawa, T; Ida, Y; Shimizu, H1
Huang, L; Huang, Z; Jin, S; Li, P; Lin, Y; Liu, H; Zheng, Y1
Khezrian, S; Salimi, A; Teymourian, H1
He, MD; Lu, YH; Wang, Y; Xiong, JC; Xu, SC; Yu, ZP; Zhang, L; Zhang, X; Zhou, Z1
Ge, X; Li, Y; Su, M; Tian, P2
Di Stefano, G; Govoni, M; Manerba, M; Vettraino, M1
Frick, L; Lamarr, W; Liu, Y; Thana, P; Turincio, R; Vanderporten, E1
Bell, EL; Fendt, SM; Guarente, L; Keibler, MA; Mayers, JR; Olenchock, BA; Stephanopoulos, G; Vander Heiden, MG; Vokes, NI; Wasylenko, TM1
Kang, TS; Korber, DR; Tanaka, T1
Shimizu, M; Takaya, N1
Hung, YP; Yellen, G1
Cruz, N; Dienel, GA; Han, X; He, W; Nedergaard, M; Oberheim Bush, NA; Takano, T; Wang, F; Wang, X; Xu, Q1
Christensen, CE; Jensen, PR; Karlsson, M; Lerche, MH; Winther, JR1
Frank, LA; Gilchrist, RB; Richani, D; Sutton-McDowall, ML; Thompson, JG1
Dawson, NJ; Katzenback, BA; Storey, KB1
Andrejeva, G; Chung, YL; Eykyn, TR; Hill, DK; Koh, DM; Leach, MO; Lin, G; Orton, MR; Parkes, HG; Robinson, SP; Wong Te Fong, AC1
Bertsch, J; Müller, V; Weghoff, MC1
Dai, C; Ding, Z; Hu, D; Hu, X; Ji, B; Luo, Y; Pan, Q; Wu, H; Xie, J1
Feist, AM; King, ZA1
Andrejeva, G; Boult, JK; Chung, YL; Eykyn, TR; Fong, AC; Griffiths, JR; Hill, DK; Jafar, M; Judson, IR; Koh, DM; Leach, MO; Lin, G; Orton, MR; Panek, R; Parkes, HG; Robinson, SP; Troy, H1
Estala, L; Ferrer, IM; Gomez, FA; Valadez, H1
Cui, YL; Fu, SL; Gao, LR; Gong, H; Jiang, X; Zhou, JJ; Zhu, CQ1
Li, Y; Liu, L; Tian, P1
Furusawa, C; Hirasawa, T; Nishii, M; Shimizu, H; Yamauchi, Y1
Bahitham, W; Bamforth, F; Chan, A; Liao, X; Mason, A; Peng, F; Sergi, C; Stone, B; Stothard, P1
Becerra, M; Cerdán, ME; González-Siso, MI; Pereira-Rodríguez, Á; Rodríguez-Belmonte, E; Touriño, A; Vizoso, Á1
Cheng, YQ; Liu, HJ; Sima, YH; Tao, H; Xu, SQ; Yin, WM1
De Angelis, M; Di Cagno, R; Filannino, P; Gobbetti, M1
Dubey, NC; Stamm, M; Tripathi, BP1
Galeffi, F; Sadgrove, MP; Shetty, PK; Turner, DA1
Jeong, MH; Kim, JH; Kwak, TH; Park, WJ; Seo, KS1
Chang, WF; Hsiung, KP; Kan, SC; Lai, WS; Lan, MC; Lin, CC; Liu, YC; Shieh, CJ1
Sasaki, S; Sato, O; Sato, Y; Sonoki, T; Suzuki, Y1
Hintermair, J; Janzon, C; Otto, AM1
Vadlani, PV; Zhang, Y1
Dong, CY; Guo, HW; Hsu, SH; Lee, OK; Wang, HW; Wei, YH; Yu, JS1
Allaman, I; Coggan, JS; Jolivet, R; Magistretti, PJ1
Barreto-Chaves, ML; Bechara, LR; Bozi, LH; Brum, PC; Coelho, Mde A; da Cunha, TF; Fortunato, RS; Gabriel-Costa, D1
Guo, C; Jiang, S; Luo, S; Shu, C; Zheng, Z1
German, NJ; Haigis, MC1
Bak, LK; Satrústegui, J1
Balasubramaniyam, S; Gulab, BR; Nehru, G; Ramakrishnan, GG; Subramanian, R; Suppuram, P1
Dong, SJ; Li, H; Lin, XH1
Asta, J; Azam, MA; Farid, T; Jaimes, R; Kay, MW; Kusha, M; Kuzmiak-Glancy, S; Lai, PF; Lopaschuk, GD; Massé, S; Nanthakumar, K; Wagg, CS1
Guo, B; Huang, Y; Li, N; Liu, Z; You, C1
Habtemariam, A; Romero-Canelón, I; Sadler, PJ; Soldevila-Barreda, JJ1
Huo, X; Ju, H; Liu, X; Zhu, J1
Cao, S; Ding, S; Shi, G; Zhang, X; Zhu, A1
Mongeon, R; Venkatachalam, V; Yellen, G1
Arts, RJ; Bonten, MJ; Cheng, SC; Cremer, OL; Giamarellos-Bourboulis, EJ; Gresnigt, MS; Joosten, LA; Kox, M; Lachmandas, E; Leentjens, J; Manjeri, GR; Netea, MG; Pickkers, P; Schultz, MJ; Scicluna, BP; van de Veerdonk, FL; van der Meer, AJ; van der Poll, T; Wagenaars, JA; Willems, PH1
Attalla, SM; Carter, WG; Christie, D; Elmorsy, E; Fikry, E; Kocon, A; Nwidu, LL; Turner, R; Warren, A1
Correani, V; d'Erme, M; Fontana, M; Forte, E; Fuso, A; Maras, B; Martire, S; Mosca, L; Scarpa, S1
Dai, Z; Lai, L; Locasale, JW; Shestov, AA1
Baek, SH; Hahn, JS; Kim, SY; Kwon, EY1
Bhatnagar, A; Chapalamadugu, KC; Cuevas, J; Katnik, C; Tipparaju, SM; Tur, J1
Park, ES; Park, S; Shin, JS1
T S, C; V T, F1
Jung, GY; Kim, KJ; Park, S; Son, HF; Yoo, TH1
Ban, HS; Harmalkar, D; Hwang, GS; Kim, BK; Kim, HM; Kim, I; Lee, H; Lee, K; Nam, M; Park, JT; Park, SK; Won, M1
Cho, YS; Chung, KS; Kim, JY; Kwon, Y; Mun, SJ; Ryu, JS; Son, MJ1
Chen, HY; Chou, JC; Huang, HY; Lai, CH; Liao, YH; Wu, CY; Wu, TY; Wu, YX; Yan, SJ1
Gao, C; Guo, X; Jiang, T; Ma, C; Sheng, B; Wang, Y; Xu, P; Yan, J; Zhang, M; Zhang, Y1
Fessel, JP; Oldham, WM1
Brebner, K; George, MAJ; Herbst, EAF; Holloway, GP; Kane, DA1
Choi, S; Choi, SJ; Choi, UJ; Jung, GY; Kim, KJ; Lee, SG; Nam, NH; Nasir, A; Park, S; Park, YS; Shim, JY; Yoo, TH1
Han, L; Liang, B; Liu, A; Song, J1
Chen, HY; Cheng, SS; Kano, K; Li, SL; Liu, CL; Liu, SM; Yen, JH1
Alruwaili, N; Kandhi, S; Sun, D; Wolin, MS1
Beard, DA; Chadwick, AE; Harrell, A; Kelly, RA; Leedale, J; Randle, LE; Webb, SD1
Benjamin, D; Colombi, M; El-Shemerly, MY; Hall, MN; Hindupur, SK; Lane, HA; Maira, SM; Moroni, C; Pohlmann, J; Robay, D1
Agius, L; Alshawi, A1
Cox, BL; Eliceiri, KW; Erickson-Bhatt, S; Fain, SB; Ludwig, KD; Macdonald, EB; Ponik, SM; Squirrell, JM; Swader, R; Szulczewski, JM1
Chobotow, J; Grzybek, M; Los, A; Ptaszynska, AA; Rowinski, R; Strachecka, A1
He, L; Jia, Y; Li, J; Li, Y; Liao, C; Yang, D; Yu, C; Yu, Z; Zhang, C1
Buddika, K; Burton, AK; Chawla, G; Gosney, CJ; Julick, CR; Karty, JA; Li, H; Luhur, A; Mahmoudzadeh, NH; Montooth, KL; Pletcher, RC; Rai, M; Sokol, NS; Sterrett, MC; Tennessen, JM1
Miller, CA; Radnai, L; Rumbaugh, G; Sellers, JR; Stremel, RF1
Altinok, O; Bowne, WB; Orynbayeva, Z; Poggio, JL; Shieh, AC; Snyder, NW; Stein, DE1
Madsen, CS; TerAvest, MA1
Keusgen, M; Pilas, J; Schöning, MJ; Selmer, T1
Goodman, RP; Ichinose, F; Marutani, E; Miyazaki, Y; Mootha, VK; Patgiri, A; Robert Bao, X; Schleifer, G; Shah, H; Sharma, R; Skinner, OS; To, TL; Zapol, WM1
Ito, K; Ito, S; Kawai, M; Kudo, K; Morita, M; Nomura, M; Sakamoto, Y; Shima, H; Tanuma, N; Yaegashi, N; Yamada, H; Yamashita, Y1
Mak, WC; Meng, L; Turner, APF1
Casalter, A; Ehrentraut, H; Ehrentraut, SF; Frede, S; Heilmann-Heimbach, S; Hoeft, A; Kleiner, JL; Klüners, A; Sivalingam, S; Weisheit, CK; Wild, L1
Ichinose, R; Katakura, Y; Kawai, M; Sano, A; Takatera, M; Yamasaki-Yashiki, S1
Li, Q; Tian, P; Wu, S; Zhao, P1
Akimova, T; Angelin, A; Baur, JA; Beier, UH; Blair, IA; Cully, MD; Eruslanov, EB; Ghanem, LR; Guo, L; Hancock, WW; Jiao, J; Kopinski, PK; Leibowitz, MS; Levine, MH; Moon, EK; Perry, C; Quinn, WJ; Schäfer, PM; Stadanlick, J; TeSlaa, T; Wallace, DC; Wang, L; Wang, Z1
Gao, X; Pu, Y; Smith, J; Wang, C; Wu, B; Xue, J1
King, A1
Abdali, A; Baci, D; Belloni, F; Bellosta, S; Corsini, A; Damiani, I; De Dominicis, C; Gelmi, ML1
Christensen, PA; Handberg, A; Rasmussen, RW; Straarup, D; Thorlacius-Ussing, O1
Barry, AP; Bonglack, EN; Cable, JM; Ch'ng, J; Christofk, HR; Dave, SS; Luftig, MA; Messinger, JE; Parnell, KM; Reinoso-Vizcaíno, NM; Russell, VS1
Daniel, R; Egelkamp, R; Harder, S; Poehlein, A; Rosenbaum, FP; Schlüter, H; Schoelmerich, MC1
Abramov, AY; Berezhnov, AV; Dolgacheva, LP; Fedotova, EI1
Gunn, B; Keniry, M; Litif, C; Lopez, A; Schuenzel, E; Udawant, S1
Abiko, Y; Kobayashi, Y; Liu, S; Otani, H; Sasaki, S; Sato, S; Shinohara, Y; Takahashi, N; Wang, X; Washio, J1
Belovich, JM; Chalhoub, ER1
Bouchez, CL; Daubon, T; Mourier, A1
Burchell, RK; Fries, R; Gal, A; Kadotani, S; Li, Z; Lopez-Villalobos, N; Petreanu, Y; Scott-Moncrieff, JC; Ulanov, AV1
Barger, C; Batsios, G; Costello, JF; Gillespie, AM; Ronen, SM; Stevers, N; Taglang, C; Tran, M; Viswanath, P1
Fowle-Grider, R; Patti, GJ; Schwaiger-Haber, M; Shriver, LP; Stancliffe, E; Wang, C; Wang, R; Wang, Y1
Han, W; Hang, Z; Liu, E; Liu, M; Liu, X; Mu, S; Sun, J; Tan, X; Wang, T; Yue, Q; Zhang, J; Zhang, Y1
Fujii, K; Fujiwara-Tani, R; Kirita, T; Kishi, S; Kuniyasu, H; Luo, Y; Miyagawa, Y; Mori, S; Mori, T; Nakashima, C; Ohmori, H; Yamamoto, K1
Antosiewicz, J; Cieminski, K; Dzik, KP; Flis, DJ; Kaczor, JJ; Wieckowski, MR; Ziolkowski, W1
Nakamura, A; Shimizu, T1
Lederer, F; Pasquier, H1
Chen, ZP; Fang, HH; Li, WD; Wu, L; Xing, ML; Zhang, YT1
Bertoncello, P; Ferraraccio, LS1
Ahn, YB; Baik, JY; Hong, JK; Kang, HI; Kim, H; Kim, S; Lee, JH1
Chen, J; Chen, Z; He, Q; Liang, J; Lin, D; Xie, Z; Yan, K1
Cao, X; Feng, J; Li, X; Sun, D; Tian, G; Wang, N; Wei, P1
Beckers, J; Birkenfeld, AL; Goj, T; Gudiksen, A; Hrabě de Angelis, M; Irmler, M; Karstoft, K; Lehmann, R; Li, Q; Maurer, J; Peter, A; Pilegaard, H; Pilmark, NS; Weigert, C; Xu, G; Zhao, X1
Gasior, FM; Justice, CN; Lee, C; Li, J; Lin, S; O'Donnell, JM; Vanden Hoek, TL; Wang, H; Zhu, X1
Choi, YS; Kim, CH; Kim, E; Lee, JE; Song, HT; Song, JE1
Carver, GE; Ghule, PN; Locknar, SA; Pung, CJ; Stein, GS; Stein, JL; Weaver, DL1

Reviews

13 review(s) available for lactic acid and nad

ArticleYear
Myocardial ischemia--metabolic pathways and implications of increased glycolysis.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 4

    Topics: Coronary Disease; Glucose; Glycogen; Glycolysis; Humans; Lactates; Lactic Acid; Myocardium; NAD; Protons

1990
Disorders of the pyruvate dehydrogenase complex.
    Journal of inherited metabolic disease, 1986, Volume: 9, Issue:2

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acidosis; Brain; Carbon Dioxide; Child; Child, Preschool; Coenzyme A; Cranial Nerves; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Facial Bones; Feedback; Humans; Lactates; Lactic Acid; Leigh Disease; Molecular Weight; Movement Disorders; NAD; Nervous System Diseases; Phosphoric Monoester Hydrolases; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Spectrophotometry

1986
Regulation of lactic acid production during exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:2

    Topics: Animals; Humans; Lactates; Lactic Acid; Muscle Contraction; Muscles; NAD; Oxidation-Reduction; Oxygen Consumption; Physical Exertion

1988
Inflammation, glycolytic metabolism, and glycosaminoglycans.
    Experimental pathology, 1986, Volume: 30, Issue:1

    Topics: Aerobiosis; Animals; Cell Division; Cells, Cultured; Glycolysis; Glycosaminoglycans; Hypoxia; Inflammation; Lactates; Lactic Acid; NAD; Wound Healing

1986
An evaluation of biochemical aspects of intravenous fructose, sorbitol and xylitol administration in man.
    Acta anaesthesiologica Scandinavica. Supplementum, 1985, Volume: 82

    Topics: Acid-Base Equilibrium; Adenosine Triphosphate; Biological Transport; Blood Glucose; Energy Metabolism; Fructose; Glucose; Glycogen; Humans; Infusions, Parenteral; Insulin; Insulin Secretion; Lactates; Lactic Acid; NAD; Phosphorylation; Pyruvates; Pyruvic Acid; Sorbitol; Triglycerides; Xylitol

1985
The anaerobic end-products of helminths.
    Parasitology, 1984, Volume: 88 ( Pt 1)

    Topics: Adenosine Triphosphate; Alcohols; Anaerobiosis; Animals; Carbohydrate Metabolism; Carbon Dioxide; Carboxylic Acids; Energy Metabolism; Glucose; Glycerol; Glycogen; Helminths; Hydrogen-Ion Concentration; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Species Specificity

1984
Metabolic engineering of lactic acid bacteria: overview of the approaches and results of pathway rerouting involved in food fermentations.
    Current opinion in biotechnology, 1999, Volume: 10, Issue:5

    Topics: Alanine; Carbon; Energy Metabolism; Enzyme Activation; Fermentation; Food Technology; Genetic Engineering; L-Lactate Dehydrogenase; Lactic Acid; Lactobacillaceae; NAD; Nitrogen; Polysaccharides, Bacterial; Vitamins

1999
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid).
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 356, Issue:1-2

    Topics: Acetyl Coenzyme A; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Ethanol; Humans; Hyperuricemia; Hypoxanthine; Lactic Acid; NAD; Oxidation-Reduction; Uric Acid; Xanthine; Xanthine Dehydrogenase

2005
Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 92, Issue:3

    Topics: Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Energy Metabolism; Glycolysis; Humans; Lactic Acid; NAD; NADP; Neoplasms; Oxidation-Reduction; Pyruvic Acid; Radiation Tolerance; Sensitivity and Specificity

2009
Regulation of glycolytic and mitochondrial metabolism by ras.
    Current pharmaceutical biotechnology, 2013, Volume: 14, Issue:3

    Topics: Animals; Epithelial Cells; Glycolysis; Humans; Lactic Acid; Mitochondria; NAD; Neoplasms; ras Proteins

2013
Sirtuins and the Metabolic Hurdles in Cancer.
    Current biology : CB, 2015, Jun-29, Volume: 25, Issue:13

    Topics: Biosynthetic Pathways; Cell Transformation, Neoplastic; Energy Metabolism; Gluconeogenesis; Humans; Lactic Acid; Models, Biological; Molecular Structure; NAD; Neoplasms; Reactive Oxygen Species; Signal Transduction; Sirtuins

2015
Fluctuations in Cytosolic Calcium Regulate the Neuronal Malate-Aspartate NADH Shuttle: Implications for Neuronal Energy Metabolism.
    Neurochemical research, 2015, Volume: 40, Issue:12

    Topics: Animals; Aspartic Acid; Calcium Signaling; Cytosol; Energy Metabolism; Humans; Lactic Acid; Malates; Mitochondria; NAD; Neurons

2015
Metabolism and Redox in Pulmonary Vascular Physiology and Pathophysiology.
    Antioxidants & redox signaling, 2019, 10-01, Volume: 31, Issue:10

    Topics: Animals; Blood Vessels; Cyclic GMP; Glucosephosphate Dehydrogenase; Glycolysis; Humans; Hypertension, Pulmonary; Lactic Acid; NAD; Oxidation-Reduction; Reactive Oxygen Species

2019

Trials

1 trial(s) available for lactic acid and nad

ArticleYear
Xylitol-induced increase in the concentration of oxypurines and its mechanism.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytosol; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Inosine; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Middle Aged; NAD; Phosphates; Pyrazinamide; Pyruvates; Pyruvic Acid; Saline Solution, Hypertonic; Serum Albumin; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines; Xylitol

1995

Other Studies

456 other study(ies) available for lactic acid and nad

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A comparative study of blood lactate analytic methods.
    International journal of sports medicine, 1992, Volume: 13, Issue:6

    Topics: Blood Chemical Analysis; Humans; Hydrogen Peroxide; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Quality Control; Reference Values; Regression Analysis; Reproducibility of Results

1992
Fluorimetric assay of D-lactate.
    Analytical biochemistry, 1992, Volume: 206, Issue:1

    Topics: Calibration; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme Stability; Fluorometry; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Reproducibility of Results; Sensitivity and Specificity

1992
Mechanism of differential inhibition of lactate dehydrogenase isoenzymes in the BMC LD-1 assay.
    Clinical biochemistry, 1992, Volume: 25, Issue:6

    Topics: Guanidines; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Thiocyanates

1992
Proposal of standard methods for the determination of enzyme catalytic concentrations in serum and plasma at 37 degrees C. IV. Lactate dehydrogenase (L-lactate: NAD+ oxidoreductase, EC 1.1.1.27). Working Group on Enzymes.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1992, Volume: 30, Issue:11

    Topics: Blood Chemical Analysis; Buffers; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Reference Standards; Reference Values

1992
Operation and energy dependence of the reducing-equivalent shuttles during lactate metabolism by isolated hepatocytes.
    Biochimica et biophysica acta, 1992, Sep-09, Volume: 1136, Issue:3

    Topics: Ammonia; Animals; Aspartic Acid; Cytoplasm; Energy Metabolism; Gluconeogenesis; Lactates; Lactic Acid; Liver; Malates; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Palmitates; Rats; Rats, Inbred Strains; Valinomycin

1992
Postanoxic oxidative injury in rat hepatocytes: lactate-dependent protection against tert-butylhydroperoxide.
    Free radical biology & medicine, 1992, Volume: 12, Issue:3

    Topics: Animals; Free Radicals; Hypoxia; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; NAD; Oxidants; Peroxides; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide

1992
An inquiry into the source of stereospecificity of lactate dehydrogenase using substrate analogues and molecular modeling.
    Biochemistry, 1992, May-05, Volume: 31, Issue:17

    Topics: Animals; Binding Sites; Computer Graphics; Dogfish; Glyoxylates; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Models, Molecular; NAD; Stereoisomerism; Substrate Specificity; Swine

1992
Hepatic dysoxia commences during O2 supply dependence.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Dogs; Hemorrhage; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Liver Diseases; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption

1992
Conversion of ammonia or urea into essential amino acids, L-leucine, L-valine, and L-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD. L-lactic dehydrogenase for coenzyme recycling.
    Applied biochemistry and biotechnology, 1990, Volume: 26, Issue:2

    Topics: Amino Acid Oxidoreductases; Amino Acids, Essential; Ammonia; Coenzymes; Dextrans; Enzyme Stability; Enzymes, Immobilized; Isoleucine; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Leucine; Leucine Dehydrogenase; NAD; Urea; Urease; Valine

1990
Kinetic comparison of caiman epsilon-crystallin and authentic lactate dehydrogenases of vertebrates.
    Journal of protein chemistry, 1991, Volume: 10, Issue:2

    Topics: Alligators and Crocodiles; Animals; Chickens; Crystallins; Ducks; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lens, Crystalline; Muscles; Myocardium; NAD; Nitroblue Tetrazolium; Pyruvates; Pyruvic Acid; Staining and Labeling; Swine

1991
Regulation of glycolysis in the erythrocyte: role of the lactate/pyruvate and NAD/NADH ratios.
    The Journal of laboratory and clinical medicine, 1991, Volume: 118, Issue:2

    Topics: Adult; Erythrocytes; Glycolysis; Humans; Lactates; Lactic Acid; NAD; Pyruvates; Pyruvic Acid

1991
Fluorimetric and high-performance liquid chromatographic determination of D-lactate in biological samples.
    Journal of chromatography, 1991, May-03, Volume: 566, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; NAD; Phenylenediamines; Pyruvates; Quality Control; Quinoxalines; Rats

1991
Ammonium ingestion prevents depletion of hepatic energy metabolites induced by acute ammonium intoxication.
    Archives of biochemistry and biophysics, 1991, Nov-01, Volume: 290, Issue:2

    Topics: Acetates; Acetoacetates; Acute Disease; Ammonia; Animals; Diet; Dose-Response Relationship, Drug; Energy Metabolism; Hydroxybutyrates; Ketoglutaric Acids; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; NAD; Phosphoenolpyruvate; Rats; Rats, Inbred Strains

1991
Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin.
    Archives of biochemistry and biophysics, 1991, Feb-01, Volume: 284, Issue:2

    Topics: Animals; Binding, Competitive; Coenzymes; Crystallins; Ducks; Heart; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Myocardium; NAD; Oxamic Acid; Pyruvates; Pyruvic Acid; Substrate Specificity; Tartronates

1991
Stimulation of alanine metabolism by ammonia in the perfused rat liver. Quantitative analysis by means of a mathematical model.
    Biochimica et biophysica acta, 1991, Mar-04, Volume: 1073, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Ammonium Chloride; Animals; Caprylates; Energy Metabolism; Female; Gluconeogenesis; Glucose; Hydroxybutyrates; Kinetics; Lactates; Lactic Acid; Liver; Mathematics; Models, Biological; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea

1991
Ascorbate is regenerated by HL-60 cells through the transplasmalemma redox system.
    Biochimica et biophysica acta, 1991, Mar-04, Volume: 1073, Issue:2

    Topics: Ascorbic Acid; Cell Count; Cell Division; Cell Line; Cell Membrane; Concanavalin A; Dehydroascorbic Acid; Ferricyanides; Free Radicals; Humans; Kinetics; Lactates; Lactic Acid; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxygen Consumption; Wheat Germ Agglutinins

1991
NADH fluorescence and regional energy metabolites during focal ischemia and reperfusion of rat brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain; Cerebral Arteries; Cerebral Cortex; Energy Metabolism; Fluorescence; Ischemic Attack, Transient; Lactates; Lactic Acid; Male; NAD; Rats; Rats, Inbred Strains; Reperfusion

1991
Effect of graded reductions of coronary pressure and flow on myocardial metabolism and performance: a model of "hibernating" myocardium.
    Journal of the American College of Cardiology, 1991, Volume: 17, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NAD; Oxygen Consumption; Rats; Rats, Inbred Strains; Ventricular Function, Left

1991
Lactate dehydrogenase from gastrocnemius muscle of turtle.
    Acta biochimica Polonica, 1990, Volume: 37, Issue:2

    Topics: Animals; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Muscles; NAD; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid; Substrate Specificity; Temperature; Turtles

1990
Menadione partially restores NADH-oxidation and ATP-synthesis in complex I deficient fibroblasts.
    Biochemistry international, 1990, Volume: 22, Issue:2

    Topics: Adenosine Triphosphate; Cells, Cultured; Fibroblasts; Glucose; Humans; Lactates; Lactic Acid; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pyruvates; Pyruvic Acid; Quinone Reductases; Rotenone; Vitamin K

1990
Why do cancer cells have such a high glycolytic rate?
    Medical hypotheses, 1990, Volume: 32, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Cell Division; Enzymes; Glucose; Glycolysis; Humans; Lactates; Lactic Acid; Mitochondria; Models, Biological; NAD; Neoplasms

1990
Development and regulation of hepatocellular fatty acid synthesis towards term: studies in isolated fetal rat hepatocytes.
    Biomedica biochimica acta, 1990, Volume: 49, Issue:7

    Topics: Animals; Caprylates; Cyclic AMP; Fatty Acids; Female; Insulin; Lactates; Lactic Acid; Liver; NAD; NADP; Pregnancy; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1990
Bioluminescent flow sensor for the determination of L-(+)-lactate.
    The Analyst, 1990, Volume: 115, Issue:7

    Topics: Alanine Transaminase; Biosensing Techniques; Body Fluids; Drug Stability; Enzymes, Immobilized; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Luminescence; NAD

1990
Flow injection analysis of L-lactate with enzyme amplification and amperometric detection.
    Analytical chemistry, 1990, Apr-01, Volume: 62, Issue:7

    Topics: Anions; Electrodes; Enzymes, Immobilized; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mixed Function Oxygenases; NAD

1990
Kinetic analysis of duck epsilon-crystallin, a lens structural protein with lactate dehydrogenase activity.
    The Biochemical journal, 1990, Apr-01, Volume: 267, Issue:1

    Topics: Animals; Chickens; Chromatography, Ion Exchange; Crystallins; Drug Stability; Ducks; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lens, Crystalline; Muscles; Myocardium; NAD; Pyruvates; Pyruvic Acid

1990
Glycolysis in permeabilized L-929 cells.
    The Biochemical journal, 1988, Oct-01, Volume: 255, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Count; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dextran Sulfate; Dextrans; Fluorescein-5-isothiocyanate; Fluoresceins; Glucose; Glycolysis; L Cells; Lactates; Lactic Acid; Mice; Microscopy, Electron; NAD; Polyethylene Glycols; Proteins

1988
Comparison of different flow injection approaches to the automatic determination of enzymatic activity.
    Journal of pharmaceutical and biomedical analysis, 1989, Volume: 7, Issue:3

    Topics: Enzymes; Hydrogen-Ion Concentration; Indicators and Reagents; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Pyruvates; Pyruvic Acid; Spectrophotometry, Ultraviolet; Temperature

1989
Inhibition of prolyl hydroxylase by poly(ADP-ribose) and phosphoribosyl-AMP. Possible role of ADP-ribosylation in intracellular prolyl hydroxylase regulation.
    The Journal of biological chemistry, 1989, May-15, Volume: 264, Issue:14

    Topics: Adenosine; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Cell Nucleus; Chick Embryo; Enzyme Activation; Fibroblasts; Hydroxylation; Lactates; Lactic Acid; Liver; Mixed Function Oxygenases; NAD; Nucleoside Diphosphate Sugars; Phosphodiesterase I; Phosphoric Diester Hydrolases; Poly Adenosine Diphosphate Ribose; Procollagen; Procollagen-Proline Dioxygenase; Rabbits; Rats

1989
Estimation of the mitochondrial redox state in human skeletal muscle during exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:2

    Topics: Adult; Ammonia; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Humans; Ketoglutaric Acids; Lactates; Lactic Acid; Male; Mitochondria, Muscle; NAD; Oxidation-Reduction; Oxygen Consumption; Physical Exertion

1989
Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates.
    Journal of neurochemistry, 1989, Volume: 52, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Brain; Carbon Dioxide; Cats; Cytochrome b Group; Female; Flavin-Adenine Dinucleotide; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic Acid; Male; Mitochondria; NAD; Organ Size; Oxygen; Oxygen Consumption; Phosphocreatine; Succinates; Succinic Acid

1989
Attenuation by dopamine uptake blockers of the inhibitory effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and some of its analogs on NADH-linked metabolism in mouse neostriatal slices.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Lactates; Lactic Acid; Male; Mice; NAD; Neurotransmitter Uptake Inhibitors; Rats; Tyrosine 3-Monooxygenase

1989
alpha-Glycerophosphate shuttle in a clonal beta-cell line.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amobarbital; Cell Line; Clone Cells; Cytosol; Electron Transport; Glucose; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycolysis; Guanosine Diphosphate; Guanosine Triphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid

1989
Lactate dehydrogenase displays absolute stereospecificity in the transfer of the prochiral hydrogen of NADH.
    The Journal of biological chemistry, 1989, Sep-15, Volume: 264, Issue:26

    Topics: Animals; Deuterium; Hydrogen; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Myocardium; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Radioisotope Dilution Technique; Stereoisomerism; Swine; Tritium

1989
Calcium uptake by bovine epididymal spermatozoa is regulated by the redox state of the mitochondrial pyridine nucleotides.
    Biology of reproduction, 1989, Volume: 40, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Ascorbic Acid; Butyrates; Butyric Acid; Calcium; Caproates; Cattle; Digitonin; Epididymis; Hydroxybutyrates; Lactates; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Pentanoic Acids; Pyruvates; Pyruvic Acid; Rotenone; Spermatozoa; Tetramethylphenylenediamine

1989
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
    Cell biology international reports, 1989, Volume: 13, Issue:9

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid

1989
Regulation of lactate/pyruvate ratios by cyclic AMP in Neurospora crassa.
    Biochemical and biophysical research communications, 1988, Jan-15, Volume: 150, Issue:1

    Topics: Adenylyl Cyclases; Chromatography, High Pressure Liquid; Cyclic AMP; Glycolysis; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mutation; NAD; Neurospora; Neurospora crassa; Pyruvates; Pyruvic Acid

1988
Crabtree effect in tumoral pancreatic islet cells.
    The Journal of biological chemistry, 1988, Feb-05, Volume: 263, Issue:4

    Topics: Adenine Nucleotides; Adenoma, Islet Cell; Animals; Glucose; Glutamine; Lactates; Lactic Acid; Lipids; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Pancreatic Neoplasms; Tumor Cells, Cultured

1988
Metabolic regulation of prolyl hydroxylase activation.
    Progress in clinical and biological research, 1988, Volume: 266

    Topics: Animals; Cells, Cultured; Chickens; Collagen; Enzyme Activation; Fibroblasts; Lactates; Lactic Acid; NAD; Poly Adenosine Diphosphate Ribose; Procollagen-Proline Dioxygenase; Rabbits

1988
Regulation of mitochondrial adenine nucleotide content in newborn rabbit liver.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine Nucleotides; Adrenergic beta-Agonists; Animals; Animals, Newborn; Bucladesine; Cytosol; Glucagon; Glucose; Hydroxybutyrates; Insulin; Isoproterenol; Kinetics; Lactates; Lactic Acid; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen; Pyruvates; Pyruvic Acid; Rabbits

1987
Cyclic GMP affects redox state and improves energy charge of ischaemic Langendorff-perfused rat heart.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2

    Topics: Animals; Coronary Disease; Cyclic GMP; Energy Metabolism; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardium; NAD; Oxidation-Reduction; Perfusion; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
Catecholamine and vasopressin stimulation of gluconeogenesis from dihydroxyacetone in the presence of atractyloside.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atractyloside; Bucladesine; Calcium; Cytosol; Dihydroxyacetone; Fructosediphosphates; Glucagon; Gluconeogenesis; Glycosides; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; Norepinephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Trioses; Vasopressins

1985
Respiratory chain defects in the mitochondria of cultured skin fibroblasts from three patients with lacticacidemia.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:5

    Topics: Adenosine Triphosphate; Cells, Cultured; Electron Transport Complex IV; Fibroblasts; Humans; Infant, Newborn; Lactates; Lactic Acid; Male; Mitochondria; NAD; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Oxygen Consumption; Pyruvates; Pyruvic Acid; Quinone Reductases; Skin

1986
Substrate utilization for lactate and energy production by heat-shocked L929 cells.
    Journal of cellular physiology, 1986, Volume: 127, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Cell Line; Citric Acid Cycle; Energy Metabolism; Fibroblasts; Glucose; Glutamine; Heat-Shock Proteins; Lactates; Lactic Acid; Mice; NAD; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid; Temperature

1986
Gluconeogenesis from serine in rabbit hepatocytes.
    Archives of biochemistry and biophysics, 1987, Aug-15, Volume: 257, Issue:1

    Topics: Animals; Cells, Cultured; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; NAD; Pyruvates; Pyruvic Acid; Rabbits; Serine; Urea

1987
Generalized seizures deplete brain energy reserves in normoxemic newborn monkeys.
    Brain research, 1988, Jun-28, Volume: 454, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Bicuculline; Brain; Callitrichinae; Energy Metabolism; Glucose; Lactates; Lactic Acid; NAD; Phosphocreatine; Seizures

1988
Contribution of non-ADH pathways to ethanol oxidation in hepatocytes from fed and hyperthyroid rats. Effect of fructose and xylitol.
    Biochemical pharmacology, 1985, Mar-01, Volume: 34, Issue:5

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Ethanol; Female; Fructose; Hyperthyroidism; Lactates; Lactic Acid; Liver; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains; Tritium; Xylitol

1985
Transmembrane ferricyanide reductase activity in Ehrlich ascites tumor cells.
    Biochimica et biophysica acta, 1988, Dec-08, Volume: 946, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Female; Glucose; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Membranes; Mice; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction

1988
Biochemical evidence that high concentrations of the antidepressant amoxapine may cause inhibition of mitochondrial electron transport.
    Toxicology and applied pharmacology, 1988, Mar-30, Volume: 93, Issue:1

    Topics: Amoxapine; Animals; Cattle; Cell Membrane; Dibenzoxazepines; Electron Transport; In Vitro Techniques; Lactates; Lactic Acid; Mitochondria; NAD; Saccharomyces cerevisiae

1988
Brain levels of NADH and NAD+ under hypoxic and hypoglycaemic conditions in vitro.
    Journal of neurochemistry, 1988, Volume: 51, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain; Female; Glucose; Guinea Pigs; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Oxygen; Phosphocreatine; Pyruvates; Pyruvic Acid

1988
Respiratory and metabolic responses of fetal and neonatal perfused livers to catecholamines and anoxia.
    Nihon Sanka Fujinka Gakkai zasshi, 1988, Volume: 40, Issue:5

    Topics: Animals; Animals, Newborn; Female; Gluconeogenesis; Glycolysis; Guinea Pigs; In Vitro Techniques; Lactates; Lactic Acid; Liver; NAD; Norepinephrine; Oxidation-Reduction; Oxygen Consumption; Perfusion; Pregnancy; Pyruvates; Pyruvic Acid

1988
NADH content in type I and type II human muscle fibres after dynamic exercise.
    The Biochemical journal, 1988, Apr-01, Volume: 251, Issue:1

    Topics: Humans; Lactates; Lactic Acid; Male; Muscles; NAD; Physical Exertion

1988
Evidence that the flux control coefficient of the respiratory chain is high during gluconeogenesis from lactate in hepatocytes from starved rats. Implications for the hormonal control of gluconeogenesis and action of hypoglycaemic agents.
    The Biochemical journal, 1987, Oct-15, Volume: 247, Issue:2

    Topics: Adenosine Triphosphate; Animals; Diuron; Fatty Acids; Glucagon; Gluconeogenesis; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; NAD; Oxidation-Reduction; Phenylephrine; Pyruvate Carboxylase; Pyruvate Kinase; Rats; Rats, Inbred Strains; Starvation

1987
Effect of glucose, NADH and NADPH on cortisol metabolism by mononuclear cells.
    The Journal of endocrinology, 1986, Volume: 109, Issue:2

    Topics: Adenosine Triphosphate; Cell Fractionation; Glucose; Humans; Hydrocortisone; Insulin; Lactates; Lactic Acid; Leukocytes; NAD; NADP

1986
Short-term changes in blood ketone body ratio in the phase immediately after liver transplantation.
    Transplantation, 1987, Volume: 43, Issue:3

    Topics: Animals; Female; Ketone Bodies; Lactates; Lactic Acid; Liver; Liver Transplantation; Male; Mitochondria, Liver; NAD; Postoperative Period; Preservation, Biological; Pyruvates; Pyruvic Acid; Swine; Tissue Preservation

1987
Inhibition of lactate production in rat brain extracts and synaptosomes by 3-[4-(reduced 3-pyridine aldehyde-adenine dinucleotide)]-pyruvate.
    Journal of neurochemistry, 1987, Volume: 48, Issue:6

    Topics: Animals; Brain; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Rats; Synaptosomes

1987
Redox state changes in human skeletal muscle after isometric contraction.
    The Journal of physiology, 1986, Volume: 380

    Topics: Adult; Female; Humans; Isometric Contraction; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles; NAD; Oxidation-Reduction; Phosphocreatine; Time Factors

1986
Acute responses of blood ketone body ratio following devascularization and revascularization of rabbit liver.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1987, Volume: 19, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine Nucleotides; Animals; Energy Metabolism; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Liver; Liver Circulation; Male; Mitochondria, Liver; NAD; Pyruvates; Pyruvic Acid; Rabbits

1987
Redox state and lactate accumulation in human skeletal muscle during dynamic exercise.
    The Biochemical journal, 1987, Jul-15, Volume: 245, Issue:2

    Topics: Adenine Nucleotides; Adult; Cytosol; Glycerophosphates; Glycolysis; Humans; Lactates; Lactic Acid; Male; Muscles; NAD; Oxidation-Reduction; Physical Exertion; Pyruvates; Pyruvic Acid

1987
Hepatic UDP-glucuronic acid regulation during acetaminophen biotransformation in rats.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Acetaminophen; Animals; Biotransformation; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Salicylamides; Uridine Diphosphate Glucose; Uridine Diphosphate Glucose Dehydrogenase; Uridine Diphosphate Glucuronic Acid; Uridine Diphosphate Sugars

1986
A 1H-NMR study of the activity expressed by lactate dehydrogenase in the human erythrocyte.
    European journal of biochemistry, 1986, Jul-15, Volume: 158, Issue:2

    Topics: Erythrocytes; Glycylglycine; Humans; Imidazoles; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Pyruvates; Pyruvic Acid

1986
The role of the hepatocellular redox state in the hepatic triglyceride accumulation following acute ethanol administration.
    Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18

    Topics: Acetaldehyde; Animals; Ethanol; Lactates; Lactic Acid; Lipid Metabolism; Liver; Male; NAD; Naloxone; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol; Triglycerides

1986
Reduction-oxidation state and protein degradation in skeletal muscles of growing rats.
    Growth, 1986,Summer, Volume: 50, Issue:2

    Topics: Animals; Body Weight; Lactates; Lactic Acid; Male; Muscle Development; Muscle Proteins; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1986
Effect of glucose and insulin administration on hepatic adenylate energy charge and the cytosolic redox state in the neonates of normal and insulin-treated diabetic rats.
    Biology of the neonate, 1985, Volume: 48, Issue:4

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Animals, Newborn; Cytosol; Diabetes Mellitus, Experimental; Energy Metabolism; Female; Glucose; Insulin; Lactates; Lactic Acid; Liver; NAD; Oxidation-Reduction; Pregnancy; Pregnancy in Diabetics; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
The effects of cyclopropane carboxylate on hepatic pyruvate metabolism.
    Archives of biochemistry and biophysics, 1985, Nov-15, Volume: 243, Issue:1

    Topics: Acyl Coenzyme A; Animals; Carbon Dioxide; Cyclopropanes; Gluconeogenesis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
[Mitochondrial myopathies and encephalomyopathies. Neuromuscular and central nervous system diseases caused by defects in mitochondrial oxidative metabolism].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1985, Volume: 133, Issue:11

    Topics: Brain; Brain Diseases, Metabolic; Carnitine O-Acetyltransferase; Child; Citric Acid Cycle; Cytochromes; Energy Metabolism; Enzymes; Humans; Lactates; Lactic Acid; Mitochondria, Muscle; Muscles; NAD; Neuromuscular Diseases; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid

1985
Red blood cell oxidative metabolism induced by hydroxypyruvaldehyde.
    Biochemical pharmacology, 1985, Apr-15, Volume: 34, Issue:8

    Topics: Adult; Blood Glucose; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Humans; In Vitro Techniques; Lactates; Lactic Acid; Malonates; Malondialdehyde; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Pentose Phosphate Pathway; Pyruvaldehyde; Pyruvates; Pyruvic Acid

1985
The rates of defined changes in protein structure during the catalytic cycle of lactate dehydrogenase.
    Biochimica et biophysica acta, 1985, Jul-01, Volume: 829, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Protein Conformation; Pyruvates; Pyruvic Acid; Swine

1985
Redox status of cultured fibroblasts. Possible relations with specific catabolic rates of proteoglycans.
    Experimental pathology, 1985, Volume: 27, Issue:1

    Topics: Aerobiosis; Anaerobiosis; Animals; Cells, Cultured; Fibroblasts; Glycolysis; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Proteoglycans; Pyruvates; Pyruvic Acid; Rats

1985
The interaction between the cytosolic pyridine nucleotide redox potential and gluconeogenesis from lactate/pyruvate in isolated rat hepatocytes. Implications for investigations of hormone action.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: Angiotensin II; Animals; Cytosol; Dexamethasone; Glucagon; Gluconeogenesis; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Lactates; Lactic Acid; Liver; Malate Dehydrogenase; Male; NAD; Oxaloacetates; Oxidation-Reduction; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
Estimation of the relative contributions of enhanced production of oxalacetate and inhibition of pyruvate kinase to acute hormonal stimulation of gluconeogenesis in rat hepatocytes. An analysis of the effects of glucagon, angiotensin II, and dexamethasone
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin II; Animals; Cytosol; Dexamethasone; Glucagon; Glucocorticoids; Gluconeogenesis; Glyceric Acids; Hormones; Kinetics; Lactates; Lactic Acid; Liver; Male; NAD; Oxaloacetates; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
Further studies on reflectometric monitoring of cerebrocortical microcirculation. Importance of lactate anions in coupling between cerebral blood flow and metabolism.
    Acta physiologica Hungarica, 1985, Volume: 66, Issue:2

    Topics: Animals; Cats; Cerebral Cortex; Hemoglobins; Lactates; Lactic Acid; Lithium; Microcirculation; NAD; Oxidation-Reduction; Regional Blood Flow; Spectrometry, Fluorescence

1985
[Methods of enzymatic lactate determination in blood without protein removal].
    Zeitschrift fur medizinische Laboratoriumsdiagnostik, 1985, Volume: 26, Issue:6

    Topics: Blood Proteins; Humans; Hydrazines; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD

1985
A radioenzymatic ultramicro method applicable to the measurement of a wide range of metabolites.
    Analytical biochemistry, 1981, Volume: 118, Issue:2

    Topics: Blood Glucose; Carbon Radioisotopes; Enzymes; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Humans; Ketoglutaric Acids; Lactates; Lactic Acid; Microchemistry; NAD; NADP; Radioisotopes

1981
Oxygen and glucose withdrawal on portal veins: NADH fluorescence and spontaneous activity.
    Archives internationales de physiologie et de biochimie, 1981, Volume: 89, Issue:4

    Topics: Adenosine Triphosphate; Aerobiosis; Animals; Female; Glucose; Kinetics; Lactates; Lactic Acid; Male; Muscle Contraction; NAD; Oxidation-Reduction; Oxygen Consumption; Portal Vein; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence

1981
Regulation of the salvage pathway of purine nucleotide synthesis by the oxidation state of NAD+ in rat heart cells.
    Archives of biochemistry and biophysics, 1984, Volume: 229, Issue:2

    Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Glycolysis; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Methylphenazonium Methosulfate; Myocardium; NAD; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1984
Reactivation of NAD(H) biosynthetic pathway by exogenous NAD+ in Nil cells severely depleted of NAD(H).
    Journal of cellular physiology, 1983, Volume: 114, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cricetinae; DNA; Fibroblasts; Glucose; Interphase; Lactates; Lactic Acid; NAD; Niacin; Niacinamide; Nicotinamide Mononucleotide; Protein Biosynthesis

1983
[NAD glucohydrolase from bovine retina].
    Bollettino della Societa italiana di biologia sperimentale, 1981, May-30, Volume: 57, Issue:10

    Topics: Anaerobiosis; Animals; Brain; Cattle; Lactates; Lactic Acid; NAD; NAD+ Nucleosidase; Rats; Retina; Subcellular Fractions; Tissue Distribution

1981
Limitations of commonly used spectrophotometric assay methods for phosphoenolypyruvate carboxykinase activity in crude extracts of muscle.
    The Biochemical journal, 1982, Jul-15, Volume: 206, Issue:1

    Topics: Animals; Bicarbonates; Carboxy-Lyases; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Muscles; NAD; Phosphoenolpyruvate Carboxylase; Pyruvate Kinase; Rats; Rats, Inbred Strains; Sodium Bicarbonate; Sodium Chloride; Spectrophotometry

1982
8-Bromo cyclic GMP inhibits NADH and lactate accumulation in hypoxic rat atria.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 323, Issue:4

    Topics: Animals; Coronary Disease; Cyclic GMP; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardium; NAD; Oxygen Consumption; Rats; Rats, Inbred Strains

1983
[Peculiarities of carbohydrate metabolism in the rat liver due to the limited accessibility of thiamine].
    Biokhimiia (Moscow, Russia), 1983, Volume: 48, Issue:11

    Topics: Adenine Nucleotides; Animals; Carbohydrate Metabolism; Cyclic AMP; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Thiamine Deficiency

1983
The effects of cyclic AMP and cyclic GMP on redox state and energy state in hypoxic rat atria.
    Life sciences, 1984, Jul-09, Volume: 35, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine Nucleotides; Animals; Cyclic GMP; Energy Metabolism; Heart Atria; Hypoxia; Lactates; Lactic Acid; Male; Myocardium; NAD; Oxidation-Reduction; Phosphocreatine; Rats; Rats, Inbred Strains

1984
Interaction of cytoplasmic dehydrogenases: quantitation of pathways of ethanol metabolism.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18 Suppl 1

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Cytoplasm; Cytosol; D-Xylulose Reductase; Ethanol; Female; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Microsomes, Liver; NAD; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases; Xylitol

1983
[Metabolic aspects of alcoholic liver damage: 1984/5 update. 1. Epidemiology and alcohol metabolism].
    Zeitschrift fur Gastroenterologie, 1984, Volume: 22, Issue:12

    Topics: Acetaldehyde; Acidosis; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Collagen; Cross-Sectional Studies; Fatty Liver, Alcoholic; Humans; Ketosis; Lactates; Lactic Acid; Liver; Liver Diseases, Alcoholic; NAD; Porphyrins; Proteins; Uric Acid

1984
The effect of ketone bodies and fatty acid on intestinal glucose metabolism during development.
    Pediatric research, 1984, Volume: 18, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animal Population Groups; Animals; Animals, Suckling; Fatty Acids; Female; Glucose; Hydroxybutyrates; Intestinal Mucosa; Ketone Bodies; Lactates; Lactic Acid; Male; NAD; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats

1984
The reversibility of cytosolic dehydrogenase reactions in hepatocytes from starved and fed rats. Effect of fructose.
    The Biochemical journal, 1984, Sep-01, Volume: 222, Issue:2

    Topics: Animals; Cytosol; Ethanol; Female; Fructose; In Vitro Techniques; Lactates; Lactic Acid; Liver; NAD; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Inbred Strains; Starvation; Thermodynamics

1984
Automated kinetic assay for lactate dehydrogenase isoenzyme 1 by centrifugal analysis after alkaline inactivation.
    Clinical chemistry, 1984, Volume: 30, Issue:11

    Topics: Autoanalysis; Centrifugation; Chemical Precipitation; Electrophoresis, Agar Gel; Erythrocytes; Evaluation Studies as Topic; Humans; Hydrogen-Ion Concentration; Immunochemistry; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Protein Denaturation; Spectrometry, Fluorescence

1984
Stimulation of glycogenolysis and platelet-activating factor production by heat-aggregated immunoglobulin G in the perfused rat liver.
    The Journal of biological chemistry, 1984, Nov-25, Volume: 259, Issue:22

    Topics: Animals; Hot Temperature; Immunoglobulin G; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; NAD; Oxygen Consumption; Perfusion; Platelet Activating Factor; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1984
Oxidation of NADH via an "external" pathway in skeletal-muscle mitochondria and its possible role in the repayment of lactacid oxygen debt.
    The International journal of biochemistry, 1984, Volume: 16, Issue:12

    Topics: Animals; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mersalyl; Mitochondria, Muscle; NAD; NADH Dehydrogenase; Oxidation-Reduction; Oxygen Consumption; Rats; Rotenone

1984
Effect of lactate and pyruvate on cerebrocortical microcirculation and NAD/NADH redox state.
    Advances in experimental medicine and biology, 1984, Volume: 180

    Topics: Animals; Cats; Cerebral Cortex; Cerebrovascular Circulation; Lactates; Lactic Acid; Microcirculation; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid

1984
L-amino acids from a racemic mixture of alpha-hydroxy acids.
    Annals of the New York Academy of Sciences, 1984, Volume: 434

    Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Pyruvates; Pyruvic Acid; Stereoisomerism

1984
The effect of intracellular oxygen concentration on lactate release, pyridine nucleotide reduction, and respiration rate in the rat cardiac tissue.
    Circulation research, 1983, Volume: 53, Issue:4

    Topics: Animals; Dopamine; Epinephrine; Glycolysis; Heart Rate; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Myoglobin; NAD; Oxidation-Reduction; Oxygen; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains

1983
The kinetic mechanism of pyruvate reduction by lactate dehydrogenase from Phycomyces blakesleeanus.
    The International journal of biochemistry, 1984, Volume: 16, Issue:2

    Topics: Fungi; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Phycomyces; Pyruvates; Pyruvic Acid

1984
The analysis of picomole amounts of L(+)- and D(-)-lactic acid in samples of dental plaque using bacterial luciferase.
    Analytical biochemistry, 1984, Volume: 136, Issue:2

    Topics: Dental Plaque; Fluorometry; Humans; Lactates; Lactic Acid; Luciferases; Luminescent Measurements; Microchemistry; NAD

1984
The effect of glyceraldehyde on red cells. Haemoglobin status, oxidative metabolism and glycolysis.
    Biochimica et biophysica acta, 1984, Jul-20, Volume: 804, Issue:3

    Topics: Blood Glucose; Erythrocytes; Glutathione; Glyceraldehyde; Glycolysis; Hemoglobins; Hexosephosphates; Humans; Lactates; Lactic Acid; Lactoylglutathione Lyase; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Thiolester Hydrolases

1984
Acute effect of ethanol on metabolite concentrations of dog pancreas in vivo.
    Alcoholism, clinical and experimental research, 1982,Fall, Volume: 6, Issue:4

    Topics: Amino Acids; Animals; Dogs; Ethanol; Female; Lactates; Lactic Acid; Male; NAD; Pancreas; Pyruvates; Pyruvic Acid

1982
Mechanism of metabolic regulation in photoassimilation of propionate in Euglena gracilis z.
    Archives of biochemistry and biophysics, 1982, Volume: 213, Issue:2

    Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Darkness; Euglena gracilis; Lactates; Lactic Acid; NAD; NADP; Photochemistry; Propionates; Subcellular Fractions

1982
Malolactic enzyme of Lactobacillus plantarum. Purification, properties, and distribution among bacteria.
    The Journal of biological chemistry, 1983, Apr-25, Volume: 258, Issue:8

    Topics: Electrophoresis, Polyacrylamide Gel; Isoelectric Point; Lactates; Lactic Acid; Lactobacillus; Malate Dehydrogenase; Malates; Manganese; Molecular Weight; NAD

1983
Age-related changes in rat adipose tissue in response to fasting: protein, lactate and pyruvate levels.
    Life sciences, 1983, Jun-06, Volume: 32, Issue:23

    Topics: Adipose Tissue; Aging; Animals; Fasting; Lactates; Lactic Acid; Male; NAD; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1983
Effect of ischemia on fatty acid metabolism in fetal lung.
    Life sciences, 1983, Aug-08, Volume: 33, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fatty Acids; Female; Fetus; Ischemia; Kinetics; Lactates; Lactic Acid; Lung; NAD; Oxidation-Reduction; Pregnancy; Pulmonary Circulation; Pyruvates; Pyruvic Acid; Rabbits

1983
Lactate metabolism and cytosolic NADH reducing equivalents in ovine adipocytes.
    The International journal of biochemistry, 1982, Volume: 14, Issue:4

    Topics: 2,4-Dinitrophenol; Adipose Tissue; Aminooxyacetic Acid; Animals; Cytosol; Dinitrophenols; Fatty Acids; Furans; Hypolipidemic Agents; Lactates; Lactic Acid; Male; NAD; Sheep

1982
Changes in NAD(P)+-dependent malic enzyme and malate dehydrogenase activities during fibroblast proliferation.
    Journal of cellular physiology, 1982, Volume: 110, Issue:2

    Topics: Cell Division; Cell Fractionation; Cells, Cultured; Fibroblasts; Humans; Lactates; Lactic Acid; Malate Dehydrogenase; Malates; Manganese; Mitochondria; NAD; NADP; Oxaloacetates; Pyruvates; Pyruvic Acid

1982
Studies of lactate dehydrogenase in the purified state and in intact erythrocytes.
    The Biochemical journal, 1982, Mar-15, Volume: 202, Issue:3

    Topics: Erythrocytes; Humans; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Biological; NAD; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid

1982
Changes in some metabolites contents of the carbohydrate metabolism in mouse submandibular salivary gland after stimulation by isoproterenol.
    General pharmacology, 1982, Volume: 13, Issue:2

    Topics: Animals; Carbohydrate Metabolism; Citrates; Citric Acid; Isoproterenol; Lactates; Lactic Acid; Male; Mice; NAD; Pyruvates; Pyruvic Acid; Submandibular Gland

1982
A simple, rapid method for the determination of glucose, lactate, pyruvate, alanine, 3-hydroxybutyrate and acetoacetate on a single 20-mul blood sample.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Jul-01, Volume: 122, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Blood Glucose; Fluorometry; Humans; Hydroxybutyrates; Keto Acids; Lactates; Lactic Acid; Methods; Microchemistry; NAD; Physical Exertion; Pyruvates; Pyruvic Acid; Spectrophotometry; Starvation

1982
Relationship of the reduction-oxidation state to protein degradation in skeletal and atrial muscle.
    Archives of biochemistry and biophysics, 1982, Volume: 217, Issue:1

    Topics: Animals; Diaphragm; Heart Atria; Lactates; Lactic Acid; Leucine; Malates; Male; Muscle Proteins; Muscles; NAD; Oxidation-Reduction; Protease Inhibitors; Pyruvates; Pyruvic Acid; Rats

1982
Intracellular oxygen supply during hypoxia.
    The American journal of physiology, 1982, Volume: 243, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Cytochromes; Glutathione; Hypoxia; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats

1982
Spin ECHO proton NMR studies of the metabolism of malate and fumarate in human erythrocytes. Dependence on free NAD levels.
    Biochimica et biophysica acta, 1982, Oct-11, Volume: 721, Issue:2

    Topics: Biological Transport; Erythrocytes; Fumarate Hydratase; Fumarates; Humans; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; NAD

1982
Determination of D-lactate in plasma.
    Methods in enzymology, 1982, Volume: 89 Pt D

    Topics: Catalysis; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Spectrophotometry

1982
A 1H n.m.r. study of the kinetic properties expressed by glyceraldehyde phosphate dehydrogenase in the intact human erythrocyte.
    The Biochemical journal, 1982, Dec-15, Volume: 208, Issue:3

    Topics: Erythrocyte Membrane; Erythrocytes; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Biological; NAD; Pyruvates; Pyruvic Acid

1982
Distinct effect of contraction and ion transport on NADH fluorescence and lactate production in uterine smooth muscle.
    Acta physiologica Academiae Scientiarum Hungaricae, 1982, Volume: 59, Issue:1

    Topics: Animals; Biological Transport; Calcium; Female; Lactates; Lactic Acid; Muscle, Smooth; NAD; Ouabain; Potassium; Pregnancy; Rabbits; Rats; Sodium; Spectrometry, Fluorescence; Uterine Contraction; Uterus

1982
A study on the function of some subcellular systems of the sheep myocardium during gousiekte. I. The energy production system.
    The Onderstepoort journal of veterinary research, 1982, Volume: 49, Issue:4

    Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Heart Failure; Lactates; Lactic Acid; Male; Mitochondria, Heart; Myocardium; NAD; Oxidative Phosphorylation; Phosphates; Phosphocreatine; Sheep; Sheep Diseases

1982
[Changes in the oxidative metabolism of the brain in the elderly].
    Neurologija, 1981, Volume: 29, Issue:1-4

    Topics: Adult; Aged; Brain; Glucose; Humans; Lactates; Lactic Acid; Middle Aged; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid

1981
Effect of increasing the intracellular ratio of NADH to NAD+ on human erythrocyte metabolism: new estimation of the turnover through the phosphoglycerate shunt.
    Archives of biochemistry and biophysics, 1981, Volume: 210, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine Nucleotides; Diphosphoglyceric Acids; Erythrocytes; Glyceric Acids; Humans; In Vitro Techniques; Lactates; Lactic Acid; NAD; Organophosphorus Compounds; Oxidation-Reduction; Phosphates; Pyruvates; Pyruvic Acid

1981
Pathways of reducing equivalents in hepatocytes from starved, ethanol-induced, and hyperthyroid rats during ethanol and xylitol metabolism.
    Archives of biochemistry and biophysics, 1981, Oct-15, Volume: 211, Issue:2

    Topics: Animals; Ethanol; Female; Glucose; Hyperthyroidism; Lactates; Lactic Acid; Liver; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains; Starvation; Triiodothyronine; Tritium; Water; Xylitol

1981
A suggested mechanism for the catalytic cycle of cytochrome bd terminal oxidase based on kinetic analysis.
    Biochemistry, 1995, Nov-14, Volume: 34, Issue:45

    Topics: Azotobacter vinelandii; Cell Membrane; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Lactates; Lactic Acid; Myoglobin; NAD; Oxidoreductases; Oxygen Consumption; Ubiquinone

1995
Hepatocyte injury resulting from the inhibition of mitochondrial respiration at low oxygen concentrations involves reductive stress and oxygen activation.
    Chemico-biological interactions, 1995, Oct-20, Volume: 98, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antimycin A; Antioxidants; Cell Death; Cell Hypoxia; Cyanides; Ethanol; Hydrogen Peroxide; Iron; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

1995
Lactate dehydrogenase M-subunit deficiencies: clinical features, metabolic background, and genetic heterogeneities.
    Muscle & nerve. Supplement, 1995, Volume: 3

    Topics: Adolescent; Adult; Base Sequence; DNA; Exercise; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Molecular Sequence Data; Mutation; Myoglobinuria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Skin Diseases

1995
Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes.
    European journal of biochemistry, 1995, Jul-15, Volume: 231, Issue:2

    Topics: 2,4-Dinitrophenol; Adenine Nucleotides; Animals; Aspartic Acid; Caprylates; Cell Separation; Dihydroxyacetone; Dinitrophenols; Electron Transport; Fatty Acids; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1995
The isoenzyme forms of lactate dehydrogenase from the testes of Uromastix hardwickii.
    Biochemistry and molecular biology international, 1994, Volume: 34, Issue:5

    Topics: Animals; Chromatography, Agarose; Colchicine; Electrophoresis, Polyacrylamide Gel; Ethanolamines; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lizards; Male; NAD; Pyruvates; Pyruvic Acid; Testis

1994
In vitro administration of ergothioneine failed to protect isolated ischaemic and reperfused rabbit heart.
    Biochimica et biophysica acta, 1995, Apr-24, Volume: 1270, Issue:2-3

    Topics: Adenine Nucleotides; Animals; Creatine Kinase; Ergothioneine; Glutathione; Glutathione Disulfide; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Reperfusion Injury; NAD; Oxidative Stress; Rabbits

1995
Impaired activation of glucose oxidation and NADPH supply in human endothelial cells exposed to H2O2 in high-glucose medium.
    Diabetes, 1995, Volume: 44, Issue:5

    Topics: Adenosine Triphosphate; Cells, Cultured; Culture Media; Diabetic Angiopathies; Endothelium, Vascular; Glucose; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glucosephosphates; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; Intracellular Fluid; Lactates; Lactic Acid; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Phosphofructokinase-1

1995
Diversity of lactate metabolism in halophilic archaea.
    Canadian journal of microbiology, 1995, Volume: 41, Issue:3

    Topics: Halobacteriaceae; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD

1995
Purification and properties of lactate dehydrogenase from liver of Uromastix hardwickii.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1995, Volume: 111, Issue:1

    Topics: Animals; Cations, Divalent; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glutamic Acid; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Lizards; Molecular Weight; NAD; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid

1995
Assay of dehydrogenases with an O2-consuming biosensor.
    Enzyme and microbial technology, 1994, Volume: 16, Issue:4

    Topics: Animals; Bacterial Proteins; Biosensing Techniques; Cell Survival; Chloromercuribenzoates; Electrodes; Electron Transport; Enzymes, Immobilized; Equipment Design; Escherichia coli; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mixed Function Oxygenases; NAD; Oxidation-Reduction; Oxidoreductases; Oxygen; p-Chloromercuribenzoic Acid; Pyruvates; Pyruvic Acid; Sensitivity and Specificity

1994
Multiple lactate dehydrogenase activities of the rumen bacterium Selenomonas ruminantium.
    Microbiology (Reading, England), 1994, Volume: 140 ( Pt 8)

    Topics: Animals; Bacterial Proteins; Fermentation; Gram-Negative Anaerobic Bacteria; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Rumen; Species Specificity

1994
Lactate oxidation coupled to energy production in mitochondria like particles from Setaria digitata, a filarial parasite.
    Biochemical and biophysical research communications, 1994, Oct-14, Volume: 204, Issue:1

    Topics: Animals; Biphenyl Compounds; Ferricyanides; Kinetics; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactates; Lactic Acid; Malonates; Mitochondria; Models, Biological; NAD; Organelles; Oxaloacetates; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Rotenone; Setaria Nematode

1994
Possible role of cell redox state on collagen metabolism in carbon tetrachloride-induced cirrhosis as evidenced by adenosine administration to rats.
    Biochimica et biophysica acta, 1994, Jul-06, Volume: 1200, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adenosine; Animals; Carbon Tetrachloride; Collagen; Hydroxybutyrates; Lactates; Lactic Acid; Liver Cirrhosis, Experimental; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1994
Metabolic consequences of a reversed pH gradient in rat tumors.
    Cancer research, 1994, Aug-01, Volume: 54, Issue:15

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbonates; Cell Membrane Permeability; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Liver Neoplasms, Experimental; Magnesium; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Methylnitrosourea; NAD; Phosphorus; Potassium; Rats; Rats, Inbred BUF; Rats, Wistar; Sarcoma, Experimental; Sodium

1994
Type-2 astrocytes have much greater susceptibility to heat stress than type-1 astrocytes.
    Journal of neuroscience research, 1994, Jun-01, Volume: 38, Issue:2

    Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cytosol; Heat-Shock Proteins; Hot Temperature; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Stress, Physiological

1994
Glycerol 3-phosphate and lactate as indicators of the cerebral cytoplasmic redox state in severe and mild hypoxia respectively: a 13C- and 31P-n.m.r. study.
    The Biochemical journal, 1993, May-01, Volume: 291 ( Pt 3)

    Topics: Acetates; Adenosine Triphosphate; Alanine; Cerebral Cortex; Cytoplasm; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerophosphates; Hypoxia, Brain; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Oxidation-Reduction; Phosphocreatine

1993
Alternatives to arginine as energy sources for the non-fermentative Mycoplasma gallinarum.
    FEMS microbiology letters, 1994, Jan-15, Volume: 115, Issue:2-3

    Topics: Acetoacetates; Arginine; Carboxylic Acids; Ethanol; Lactates; Lactic Acid; Mycoplasma; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid

1994
Redox state in liver mitochondria in acute copper sulfate poisoning.
    Life sciences, 1994, Volume: 54, Issue:14

    Topics: 3-Hydroxybutyric Acid; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Copper; Copper Sulfate; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Poisoning; Rats; Rats, Wistar; Shock, Hemorrhagic

1994
Effect of culture conditions on the NADH/NAD ratio and total amounts of NAD(H) in chemostat cultures of Enterococcus faecalis NCTC 775.
    FEMS microbiology letters, 1994, Mar-01, Volume: 116, Issue:3

    Topics: Acetates; Acetic Acid; Aerobiosis; Anaerobiosis; Bacteriological Techniques; Enterococcus faecalis; Ethanol; Gluconates; Glucose; Lactates; Lactic Acid; NAD; Oxidation-Reduction

1994
Zinc ions bound to chimeric His4/lactate dehydrogenase facilitate decarboxylation of oxaloacetate.
    Protein engineering, 1993, Volume: 6, Issue:8

    Topics: Amino Acid Sequence; Base Sequence; Geobacillus stearothermophilus; Histidine; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Metalloproteins; Molecular Sequence Data; NAD; Oxaloacetates; Peptides; Recombinant Fusion Proteins; Zinc

1993
The role of lipoic acid in product formation by Enterococcus faecalis NCTC 775 and reconstitution in vivo and in vitro of the pyruvate dehydrogenase complex.
    Journal of general microbiology, 1993, Volume: 139 Pt 6

    Topics: Acetoin; Aerobiosis; Anaerobiosis; Enterococcus faecalis; Fermentation; Glucose; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; NAD; Pyruvate Dehydrogenase Complex; Thioctic Acid

1993
Effects of ethanol on urinary acidification and on gluconeogenesis by isolated renal tubules.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:10

    Topics: Amino Acids; Animals; Carbohydrate Metabolism; Cytosol; Diet; Ethanol; Female; Fomepizole; Gluconeogenesis; Glucose; Glutamine; Hydrogen-Ion Concentration; Kidney Tubules; Lactates; Lactic Acid; Male; Mitochondria; NAD; Oleic Acid; Oleic Acids; Oxidation-Reduction; Pyrazoles; Pyruvates; Rats; Rats, Wistar; Serum Albumin; Time Factors; Urine

1993
Lactate stimulation of macrophage-derived angiogenic activity is associated with inhibition of Poly(ADP-ribose) synthesis.
    Laboratory investigation; a journal of technical methods and pathology, 1996, Volume: 74, Issue:3

    Topics: Animals; Cells, Cultured; Cornea; Lactates; Lactic Acid; Macrophages; NAD; Neovascularization, Physiologic; Niacinamide; Oxidation-Reduction; Poly Adenosine Diphosphate Ribose; Rabbits

1996
Effects of the nonsteroidal anti-inflammatory drug piroxicam on energy metabolism in the perfused rat liver.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1996, Volume: 113, Issue:1

    Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimycin A; Atractyloside; Drug Interactions; Energy Metabolism; Fasting; Gluconeogenesis; Glucose; Glycogen; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxygen Consumption; Perfusion; Piroxicam; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1996
Serum lactate and lactate dehydrogenase in high concentrations interfere in enzymatic assay of ethylene glycol.
    Clinical chemistry, 1996, Volume: 42, Issue:9

    Topics: Adult; Chromatography, Gas; Clinical Enzyme Tests; Ethylene Glycol; Ethylene Glycols; False Positive Reactions; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; NAD; Retrospective Studies

1996
Continuous enzyme-linked fluorometric detection of L-(+)-lactate released from rat brain vesicles under anoxic conditions.
    Journal of neuroscience methods, 1996, Volume: 67, Issue:2

    Topics: Animals; Brain Chemistry; Calcium; Enzyme-Linked Immunosorbent Assay; Fura-2; Hypoxia, Brain; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; NAD; Oxygen Consumption; Rats; Rats, Wistar; Sodium; Spectrometry, Fluorescence; Tetrodotoxin

1996
Metabolic adaptation during a sequence of no-flow and low-flow ischemia. A possible trigger for hibernation.
    Circulation, 1996, Nov-15, Volume: 94, Issue:10

    Topics: Adaptation, Physiological; Animals; Biomechanical Phenomena; Calcium; Coronary Circulation; Creatine Kinase; Energy Metabolism; Heart; Homeostasis; Lactic Acid; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Stunning; Myocardium; NAD; Phosphates; Purines; Rabbits

1996
The acetate kinase of Clostridum acetobutylicum strain P262.
    Archives of microbiology, 1996, Volume: 166, Issue:6

    Topics: Acetate Kinase; Acetates; Chromatography, Agarose; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Clostridium; Electrophoresis, Polyacrylamide Gel; Fermentation; Glucose; Hydrogen-Ion Concentration; Lactic Acid; NAD; Phosphate Acetyltransferase; Phosphotransferases (Carboxyl Group Acceptor); Pyruvic Acid

1996
Hepatic glucose production from L-alanine is absent in perfused liver of diabetic rats.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 95, Issue:2

    Topics: Alanine; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glycerol; Infusions, Intravenous; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Software; Sorbitol; Streptozocin

1997
Determination of D-lactate by enzymatic methods in biological fluids: study of interferences.
    Clinical chemistry, 1997, Volume: 43, Issue:6 Pt 1

    Topics: Body Fluids; Hemofiltration; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; NAD; Pleura; Spectrophotometry; Stereoisomerism

1997
A model of Plasmodium falciparum lactate dehydrogenase and its implications for the design of improved antimalarials and the enhanced detection of parasitaemia.
    Protein engineering, 1997, Volume: 10, Issue:4

    Topics: Amino Acid Sequence; Animals; Antimalarials; Binding Sites; Crystallography, X-Ray; Drug Design; Geobacillus stearothermophilus; Gossypol; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Models, Molecular; Molecular Sequence Data; NAD; Plasmodium falciparum; Protein Structure, Tertiary; Sequence Alignment; Sequence Deletion; Stereoisomerism; Swine

1997
Control of the shift from homolactic acid to mixed-acid fermentation in Lactococcus lactis: predominant role of the NADH/NAD+ ratio.
    Journal of bacteriology, 1997, Volume: 179, Issue:17

    Topics: Acetyltransferases; Fermentation; Galactose; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Lactococcus lactis; Lactose; NAD; Pyruvic Acid

1997
Pyruvate improves deleterious effects of high glucose on activation of pentose phosphate pathway and glutathione redox cycle in endothelial cells.
    Diabetes, 1997, Volume: 46, Issue:12

    Topics: Adenosine Triphosphate; Cells, Cultured; Endothelium, Vascular; Fructosediphosphates; Glucose; Glutathione; Humans; Hydrogen Peroxide; Lactic Acid; NAD; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvic Acid; Umbilical Veins

1997
Pyruvate augments calcium transients and cell shortening in rat ventricular myocytes.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Animals; Calcium; Cells, Cultured; Cytosol; Glucose; Heart; Heart Ventricles; Lactic Acid; Male; Mitochondria, Heart; Models, Cardiovascular; Myocardial Contraction; Myocardium; NAD; NADP; Phosphorylation; Pyruvic Acid; Rats; Rats, Wistar

1998
Effect of chronic ethanol consumption on respiratory and glycolytic activities of rat periportal and perivenous hepatocytes.
    Archives of biochemistry and biophysics, 1998, Feb-15, Volume: 350, Issue:2

    Topics: Adenosine Triphosphate; Alcohol Drinking; Anaerobiosis; Animals; Ascorbic Acid; Cell Respiration; Cells, Cultured; Ethanol; Glucosyltransferases; Glycogen; Glycolysis; Glycoproteins; Lactic Acid; Liver; Male; Mice; NAD; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1998
Requirement for ubiquinone downstream of cytochrome(s) b in the oxygen-terminated respiratory chains of Escherichia coli K-12 revealed using a null mutant allele of ubiCA.
    Microbiology (Reading, England), 1998, Volume: 144 ( Pt 2)

    Topics: Aerobiosis; Alkyl and Aryl Transferases; Alleles; Anaerobiosis; Cell Membrane; Cloning, Molecular; Cytochrome b Group; DNA, Bacterial; Electron Transport; Escherichia coli; Fumarates; Lactic Acid; NAD; Nitrates; Oxidation-Reduction; Oxo-Acid-Lyases; Oxygen; Plasmids; Polymerase Chain Reaction; Ubiquinone

1998
Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum.
    Molecular and biochemical parasitology, 1997, Dec-01, Volume: 90, Issue:1

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Enzyme Inhibitors; Gossypol; Humans; Isoelectric Point; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; NAD; Plasmodium falciparum; Pyruvic Acid; Recombinant Proteins; Substrate Specificity

1997
Inhibition of nitric oxide synthesis aggravates myocardial ischemia in hemorrhagic shock in constant pressure model.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aorta; Catecholamines; Disease Models, Animal; Dogs; Enzyme Inhibitors; Fluorescence; Freezing; Hemodynamics; Lactic Acid; Myocardial Ischemia; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen; Shock, Hemorrhagic

1998
Investigation of the yeast mitochondrial unselective channel in intact and permeabilized spheroplasts.
    Biochemistry and molecular biology international, 1998, Volume: 44, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane Permeability; Cell Respiration; Deoxyglucose; Ion Channels; Lactic Acid; Mitochondria; NAD; Nystatin; Phosphates; Saccharomyces cerevisiae; Sorbitol; Spheroplasts; Triethyltin Compounds

1998
The importance of the glycerol 3-phosphate shuttle during aerobic growth of Saccharomyces cerevisiae.
    Yeast (Chichester, England), 1998, Mar-15, Volume: 14, Issue:4

    Topics: Aerobiosis; Ethanol; Glycerol; Glycerol-3-Phosphate Dehydrogenase (NAD+); Glycerolphosphate Dehydrogenase; Glycerophosphates; Hydrogen-Ion Concentration; Isoenzymes; Lactic Acid; Mutation; NAD; NADH Dehydrogenase; Oxidation-Reduction; Pyruvic Acid; Saccharomyces cerevisiae

1998
Changes in the redox state in the retina and brain during the onset of diabetes in rats.
    Neurochemical research, 1998, Volume: 23, Issue:6

    Topics: Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; L-Lactate Dehydrogenase; Lactic Acid; Lens, Crystalline; Liver; NAD; Oxidation-Reduction; Pigment Epithelium of Eye; Pyruvic Acid; Rats; Retina

1998
A sensitive equilibrium-based assay for D-lactate using D-lactate dehydrogenase: application to penicillin-binding protein/DD-carboxypeptidase activity assays.
    Analytical biochemistry, 1998, May-15, Volume: 259, Issue:1

    Topics: Amino Acid Sequence; Bacterial Proteins; Carrier Proteins; Cell Wall; Escherichia coli; Hexosyltransferases; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Leuconostoc; Membrane Glycoproteins; Muramoylpentapeptide Carboxypeptidase; NAD; Penicillin-Binding Proteins; Peptidyl Transferases; Sensitivity and Specificity; Staphylococcus aureus

1998
Pantothenol protects rats against some deleterious effects of gamma radiation.
    Free radical biology & medicine, 1998, Volume: 24, Issue:6

    Topics: Animals; Antioxidants; beta Carotene; Cholesterol; Coenzyme A; Drug Administration Schedule; Female; Gamma Rays; Glutathione; Glutathione Disulfide; Intubation, Gastrointestinal; Lactic Acid; Lipids; Liver; Malate Dehydrogenase; Malate Dehydrogenase (NADP+); NAD; Pantothenic Acid; Phospholipids; Proteins; Pyruvic Acid; Radiation-Protective Agents; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances

1998
Oxidative phosphorylation in intact hepatocytes: quantitative characterization of the mechanisms of change in efficiency and cellular consequences.
    Molecular and cellular biochemistry, 1998, Volume: 184, Issue:1-2

    Topics: 2,4-Dinitrophenol; Adenosine Triphosphatases; Adenosine Triphosphate; Almitrine; Animals; Caprylates; Cells, Cultured; Dihydroxyacetone; Lactic Acid; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Proton Pumps; Pyruvic Acid; Rats; Rats, Wistar; Thermodynamics

1998
Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Animals; Enzyme Inhibitors; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxidation-Reduction; Plasmodium falciparum; Pyruvic Acid; Sesquiterpenes

1998
Membrane D-lactate oxidase in Zymomonas mobilis: evidence for a branched respiratory chain.
    FEMS microbiology letters, 1998, Nov-01, Volume: 168, Issue:1

    Topics: Aerobiosis; Chlorpromazine; Cytochromes; Electron Transport; Lactic Acid; Methacrylates; Mixed Function Oxygenases; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxygen Consumption; Spectrophotometry; Thiazoles; Zymomonas

1998
FAD-mediated enzymatic conversion of NAD+ to NADH: application to chiral synthesis of L-lactate.
    Bioorganic & medicinal chemistry letters, 1998, Oct-20, Volume: 8, Issue:20

    Topics: Dihydrolipoamide Dehydrogenase; Electrochemistry; Electrodes; Enzymes, Immobilized; Flavin-Adenine Dinucleotide; Lactic Acid; NAD

1998
Fatty acids and glycerol or lactate are required to induce gluconeogenesis from alanine in isolated rabbit renal cortical tubules.
    Amino acids, 1999, Volume: 16, Issue:1

    Topics: Alanine; Animals; Fatty Acids; Gluconeogenesis; Glucose; Glycerol; Glycerophosphates; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Lactic Acid; Male; NAD; Oxygen; Rabbits

1999
Retention and regeneration of native NAD(H) in noncharged ultrafiltration membrane reactors: application to L-lactate and gluconate production.
    Biotechnology and bioengineering, 1998, Mar-05, Volume: 57, Issue:5

    Topics: Bioreactors; Biotechnology; Enzyme Stability; Gluconates; Glucose 1-Dehydrogenase; Glucose Dehydrogenases; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Membranes; Models, Biological; NAD; Polyethyleneimine; Ultrafiltration

1998
Chondrocyte death is linked to development of a mitochondrial membrane permeability transition in the growth plate.
    Journal of cellular physiology, 1999, Volume: 179, Issue:3

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Carbocyanines; Cell Membrane Permeability; Cellular Senescence; Chickens; Chondrocytes; Dinitrophenols; Electron Transport; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Gene Expression; Glucose; Growth Plate; Intracellular Membranes; Lactic Acid; Mitochondria; NAD; Oxidation-Reduction; Phosphates; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uncoupling Agents

1999
Energy metabolism and NAD-NADH redox state in brain slices in response to glutamate exposure and ischemia.
    Metabolic brain disease, 1999, Volume: 14, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Energy Metabolism; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Lactic Acid; NAD; Oxidation-Reduction; Phosphates; Phosphorylation; Rats; Rats, Sprague-Dawley

1999
A general method for relieving substrate inhibition in lactate dehydrogenases.
    Protein engineering, 1999, Volume: 12, Issue:6

    Topics: Enzyme Inhibitors; Escherichia coli; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Mutagenesis, Site-Directed; Myocardium; NAD; Pyruvic Acid

1999
Study of single-molecule dynamics and reactions with classic light microscopy.
    Cytometry, 1999, Jul-01, Volume: 36, Issue:3

    Topics: Bacteriophage lambda; Deoxyribonucleases, Type II Site-Specific; DNA, Viral; L-Lactate Dehydrogenase; Lactic Acid; Microinjections; Microscopy, Fluorescence; NAD; NADP; Pyruvic Acid

1999
Frequency-dependent fatigue development during electrical stimulation in the masseter muscle of pigtail monkeys.
    Journal of orofacial pain, 1998,Fall, Volume: 12, Issue:4

    Topics: Animals; Bite Force; Electric Stimulation; Electromyography; Female; Glucose; Glycogen; Lactic Acid; Macaca nemestrina; Male; Masseter Muscle; Muscle Fatigue; NAD; Phosphocreatine; Pyruvic Acid

1998
The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis.
    European journal of biochemistry, 1999, Volume: 265, Issue:3

    Topics: Adenosine Triphosphate; Animals; Epinephrine; Glucagon; Glucose; Glycolysis; Homeostasis; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Liver Glycogen; Mitochondria, Liver; Models, Biological; NAD; Protons; Pyruvic Acid; Rats

1999
Induction of lactate production associated with a decrease in NADH cell content enables growth resumption of Clostridium cellulolyticum in batch cultures on cellobiose.
    Research in microbiology, 1999, Volume: 150, Issue:7

    Topics: Acetates; Carbon Monoxide; Cellobiose; Clostridium; Culture Media; Ethanol; Hydrogen; Kinetics; Lactic Acid; NAD

1999
Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes.
    European journal of biochemistry, 1999, Volume: 266, Issue:3

    Topics: Adenosine Triphosphate; Animals; Feedback; Glycolysis; Lactic Acid; Liver; Membrane Potentials; Mitochondria, Liver; Models, Biological; NAD; Oxidative Phosphorylation; Oxygen Consumption; Rats

1999
Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.
    Biology of reproduction, 2000, Volume: 62, Issue:1

    Topics: Animals; Blastocyst; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Fluorescence; Glucose; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; NAD; Oxidation-Reduction; Pregnancy; Pyruvic Acid; Zygote

2000
Extracellular oxidoreduction potential modifies carbon and electron flow in Escherichia coli.
    Journal of bacteriology, 2000, Volume: 182, Issue:3

    Topics: Acetic Acid; Acetyl Coenzyme A; Alcohol Dehydrogenase; Carbon; Carbon Dioxide; Electrons; Escherichia coli; Ethanol; Fermentation; Formates; Lactic Acid; Models, Chemical; NAD; Oxaloacetates; Oxidation-Reduction; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxylase; Pyruvate Kinase; Succinic Acid

2000
Age-dependent changes in glycosaminoglycan content in the skin of fasted rats. A possible mechanism.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2000, Volume: 52, Issue:2

    Topics: Aging; Animals; Blood Glucose; Fasting; Glycosaminoglycans; Lactic Acid; Male; NAD; Pyruvic Acid; Rats; Rats, Wistar; Skin; Uronic Acids

2000
D-Glucose prevents glutathione oxidation and mitochondrial damage after glutamate receptor stimulation in rat cortical primary neurons.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Adenosine Triphosphate; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Energy Metabolism; Glucose; Glutathione; Lactic Acid; Mitochondria; NAD; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

2000
NADH/NAD redox state of cytoplasmic glycolytic compartments in vascular smooth muscle.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Carotid Arteries; Cell Compartmentation; Cytoplasm; Energy Metabolism; Enzyme Inhibitors; Glycolysis; In Vitro Techniques; Lactic Acid; Muscle, Smooth, Vascular; NAD; Ouabain; Oxidation-Reduction; Sodium-Potassium-Exchanging ATPase; Swine

2000
Glycolytic enzyme activity in hypotonically treated boar spermatozoa.
    Reproduction, fertility, and development, 1999, Volume: 11, Issue:7-8

    Topics: Adenosine Diphosphate; Animals; Buffers; Dihydroxyacetone Phosphate; Fructosediphosphates; Glyceraldehyde 3-Phosphate; Glyceric Acids; Glycolysis; Hypotonic Solutions; L-Lactate Dehydrogenase; Lactic Acid; Male; NAD; Phosphates; Phosphofructokinase-1; Pyruvic Acid; Spermatozoa; Swine

1999
Metabolic adaptation of the hypertrophied heart: role of the malate/aspartate and alpha-glycerophosphate shuttles.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:12

    Topics: Adenosine Triphosphate; Animals; Aorta; Aspartic Acid; Atrial Natriuretic Factor; Blotting, Northern; Cardiomegaly; Fatty Acids; Glucose; Glycerophosphates; Immunoblotting; Lactic Acid; Malate Dehydrogenase; Malates; Male; Mitochondria; Models, Biological; Myocardium; NAD; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

2000
Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:3

    Topics: Adenosine Triphosphate; Aspartic Acid; Citric Acid Cycle; Energy Metabolism; Fatty Acids, Nonesterified; Flavin-Adenine Dinucleotide; Fumarate Hydratase; Gene Deletion; Glucose; Glycerophosphates; Glycolysis; Humans; Lactic Acid; Malates; Mitochondria; Models, Biological; Mutation; NAD; Oxygen Consumption; Palmitic Acid; Phosphofructokinase-1; Pyruvate Dehydrogenase Complex

2001
An integrated NAD+-dependent enzyme-functionalized field-effect transistor (ENFET) system: development of a lactate biosensor.
    Biosensors & bioelectronics, 2000, Volume: 15, Issue:11-12

    Topics: Biosensing Techniques; L-Lactate Dehydrogenase; Lactic Acid; NAD; PQQ Cofactor; Quinolones; Quinones

2000
Inhibitory effect of sorbitol on sugar metabolism of Streptococcus mutans in vitro and on acid production in dental plaque in vivo.
    Oral microbiology and immunology, 2001, Volume: 16, Issue:2

    Topics: Acetic Acid; Acetyltransferases; Adult; Aged; Dental Plaque; Female; Formates; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Hydrogen-Ion Concentration; Ion-Selective Electrodes; Lactic Acid; Middle Aged; NAD; Oxygen; Pyruvic Acid; Sorbitol; Streptococcus mutans; Sucrose

2001
Paradoxical effects of copper and manganese on brain mitochondrial function.
    Life sciences, 2001, Feb-23, Volume: 68, Issue:14

    Topics: 2,6-Dichloroindophenol; Animals; Brain Chemistry; Coloring Agents; Copper; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Malates; Male; Manganese; Mitochondria; Monoamine Oxidase; NAD; Oxidation-Reduction; Rats; Rats, Wistar; Succinic Acid

2001
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
    Pharmacology, 2001, Volume: 62, Issue:3

    Topics: Adrenergic alpha-Antagonists; Ammonia; Animals; Antioxidants; Cell Fractionation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Glutamic Acid; Imidazoles; Imidazolidines; Ketoglutaric Acids; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Piperazines; Prazosin; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Thioctic Acid

2001
Rates of gluconeogenesis in perfused liver of alloxan-diabetic fed rats.
    Research communications in molecular pathology and pharmacology, 2000, Volume: 107, Issue:1-2

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fructose; Gluconeogenesis; Glucose; Glutamine; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Uric Acid

2000
NADH: sensor of blood flow need in brain, muscle, and other tissues.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:8

    Topics: Animals; Brain; Cytosol; Lactic Acid; Muscle Contraction; Muscles; NAD; Physical Conditioning, Animal; Pyruvic Acid; Rats; Regional Blood Flow; Seizures; Signal Transduction; Vibrissae

2001
Metabolic flux analysis of Clostridium thermosuccinogenes: effects of pH and culture redox potential.
    Applied biochemistry and biotechnology, 2001, Volume: 94, Issue:1

    Topics: Acetic Acid; Carbohydrate Metabolism; Clostridium; Ethanol; Fermentation; Formates; Hydrogen-Ion Concentration; Lactic Acid; NAD; Oxidation-Reduction; Succinic Acid

2001
Allosteric activation of pyruvate kinase via NAD+ in rat liver cells.
    European journal of biochemistry, 2001, Volume: 268, Issue:14

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Cell Separation; Dihydroxyacetone Phosphate; Energy Metabolism; Lactic Acid; Liver; Male; NAD; Niacinamide; Phosphoenolpyruvate; Pyruvate Kinase; Pyruvic Acid; Rats; Rats, Wistar

2001
Is ischemia involved in the pathogenesis of murine cerebral malaria?
    The American journal of pathology, 2001, Volume: 159, Issue:3

    Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Female; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Malaria, Cerebral; Mice; Mice, Inbred CBA; NAD; Osmolar Concentration; Pyruvic Acid

2001
Effect of exogenous lactate on rat glioma metabolism.
    Journal of neuroscience research, 2001, Sep-15, Volume: 65, Issue:6

    Topics: Animals; Blood Glucose; Brain; Brain Neoplasms; Carbon; Carbon Radioisotopes; Citric Acid Cycle; Energy Metabolism; Female; Glioma; Glucose; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Neurons; Rats; Rats, Wistar; Tumor Cells, Cultured

2001
Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa.
    Biology of reproduction, 2001, Volume: 65, Issue:4

    Topics: Animals; Cell Membrane; Epididymis; Lactic Acid; Leukocytes; Malates; Male; Mitochondria; NAD; NADP; NADPH Oxidases; Oligomycins; Onium Compounds; Oxidation-Reduction; Rats; Reactive Oxygen Species; Rotenone; Spermatozoa; Succinic Acid; Superoxides; Uncoupling Agents; Zinc

2001
Effects of hematocrit on cerebral microcirculation and tissue oxygenation during deep hypothermic bypass.
    Circulation, 2001, Sep-18, Volume: 104, Issue:12 Suppl 1

    Topics: Animals; Body Temperature; Cardiopulmonary Bypass; Cell Adhesion; Cell Count; Cerebrovascular Circulation; Endothelium, Vascular; Heart Arrest; Hematocrit; Hemodynamics; Hypothermia, Induced; Lactic Acid; Leukocyte Count; Leukocytes; Microcirculation; Microscopy, Fluorescence; NAD; Oxygen Consumption; Parietal Lobe; Swine

2001
Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:1

    Topics: Animals; Cattle; Cell Membrane; Cells, Cultured; Deoxyglucose; Electron Transport; Endothelium, Vascular; Intracellular Membranes; Iodoacetates; Lactic Acid; NAD; Oxidation-Reduction; Pulmonary Artery

2002
[Insulin-like growth factor 1 regulates collagen synthesis of periodontal ligament cells by a mechanism involving inhibition of poly(ADP-ribose) synthesis].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 1998, Volume: 33, Issue:1

    Topics: Cells, Cultured; Collagen; Humans; Insulin-Like Growth Factor I; Lactic Acid; NAD; Periodontal Ligament; Poly Adenosine Diphosphate Ribose

1998
Immobilisation of enzymes on poly(aniline)-poly(anion) composite films. Preparation of bioanodes for biofuel cell applications.
    Bioelectrochemistry (Amsterdam, Netherlands), 2002, Volume: 55, Issue:1-2

    Topics: Aniline Compounds; Animals; Anions; Electrodes; Enzymes, Immobilized; L-Lactate Dehydrogenase; Lactic Acid; NAD; Polymers; Rabbits

2002
Insulin increases NADH/NAD+ redox state, which stimulates guanylate cyclase in vascular smooth muscle.
    American journal of hypertension, 2002, Volume: 15, Issue:3

    Topics: Animals; Cells, Cultured; Cyclic GMP; Dogs; Guanylate Cyclase; Indazoles; Insulin; Isocitrates; Lactic Acid; Muscle, Smooth, Vascular; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxaloacetic Acid; Oxidation-Reduction; Pyruvic Acid; Stimulation, Chemical

2002
Mechanistic model of myocardial energy metabolism under normal and ischemic conditions.
    Annals of biomedical engineering, 2002, Volume: 30, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Computer Simulation; Coronary Circulation; Energy Metabolism; Fatty Acids; Glycogen; Heart; Humans; Lactic Acid; Models, Cardiovascular; Myocardial Ischemia; Myocardium; NAD; Oxygen; Sensitivity and Specificity; Swine

2002
Integration of polyaniline/poly(acrylic acid) films and redox enzymes on electrode supports: an in situ electrochemical/surface plasmon resonance study of the bioelectrocatalyzed oxidation of glucose or lactate in the integrated bioelectrocatalytic system
    Journal of the American Chemical Society, 2002, Jun-05, Volume: 124, Issue:22

    Topics: Acrylic Resins; Aniline Compounds; Electrodes; Glucose; Glucose Oxidase; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxidation-Reduction; Surface Plasmon Resonance

2002
Effect of glucose on glycerol bioconversion by Lactobacillus reuteri.
    Applied microbiology and biotechnology, 2002, Volume: 59, Issue:2-3

    Topics: Aldehydes; Culture Media; Glucose; Glyceraldehyde; Glycerol; Lactic Acid; Lactobacillus; NAD; Propane

2002
Lactate -- the forgotten fuel!
    The Journal of physiology, 2002, Jul-15, Volume: 542, Issue:Pt 2

    Topics: Exercise; Heart; Humans; Lactic Acid; Muscle, Skeletal; NAD; NADP

2002
Switch to anaerobic glucose metabolism with NADH accumulation in the beta-cell model of mitochondrial diabetes. Characteristics of betaHC9 cells deficient in mitochondrial DNA transcription.
    The Journal of biological chemistry, 2002, Nov-01, Volume: 277, Issue:44

    Topics: Anaerobiosis; Animals; Calcium; Cell Count; Cells, Cultured; Diabetes Mellitus; DNA, Mitochondrial; Ethidium; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; L-Lactate Dehydrogenase; Lactic Acid; Membrane Potentials; Mice; Mitochondria; NAD; Transcription, Genetic

2002
Phosphite dehydrogenase: a versatile cofactor-regeneration enzyme.
    Angewandte Chemie (International ed. in English), 2002, Sep-02, Volume: 41, Issue:17

    Topics: Kinetics; L-Lactate Dehydrogenase; Lactic Acid; NAD; NADH, NADPH Oxidoreductases; NADP; Pyruvic Acid; Thermodynamics

2002
Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Acid-Base Equilibrium; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blood Pressure; Caspases; Glutathione; Glutathione Disulfide; Lactic Acid; Liver; Microdialysis; Mitochondria; NAD; NADP; Osmolar Concentration; Oxidation-Reduction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyruvic Acid; Shock, Hemorrhagic; Swine

2002
Glucose metabolism of lactic acid bacteria changed by quinone-mediated extracellular electron transfer.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:10

    Topics: Aerobiosis; Anaerobiosis; Benzoquinones; Biological Transport; Culture Media; Electron Transport; Extracellular Space; Glucose; Lactic Acid; Lactobacillus; Lactococcus lactis; NAD; Naphthoquinones; Oxidation-Reduction; Propionibacterium

2002
MPP(+) causes inhibition of cellular energy supply in cerebellar granule cells.
    Neurotoxicology, 2003, Volume: 24, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dopamine Agents; Dose-Response Relationship, Drug; Energy Metabolism; Female; Glucose; Glycolysis; Lactic Acid; Male; Mitochondria; NAD; Neurons; Nucleotides; Rats; Rats, Wistar

2003
Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and -independent mechanisms.
    The Journal of physiology, 2003, Aug-01, Volume: 550, Issue:Pt 3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caffeine; Calcium; Energy Metabolism; Flavoproteins; Heart; Homeostasis; Hydrogen; In Vitro Techniques; Lactic Acid; Mitochondria, Heart; Myocardium; NAD; Oxidative Phosphorylation; Phosphodiesterase Inhibitors; Pyruvates; Rats; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum

2003
Pharmacological biotin supplementation maintains biotin status and function in rats administered dietary carbamazepine.
    The Journal of nutrition, 2003, Volume: 133, Issue:9

    Topics: Animals; Anticonvulsants; Biotin; Brain; Carbamazepine; Dietary Supplements; Dose-Response Relationship, Drug; Lactic Acid; Liver; Male; NAD; Osmolar Concentration; Pyruvate Carboxylase; Rats; Rats, Sprague-Dawley

2003
[Optic-enzymic determination of L-(+)-lactic acid by a diphosphopyridine nucleotide independent lactic acid dehydrogenase from yeast].
    Biochemische Zeitschrift, 1958, Volume: 329, Issue:7

    Topics: Eye; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxidoreductases; Saccharomyces cerevisiae; Yeast, Dried

1958
[Hydrogen transfer from reduced triphosphopyridine nucleotide to diphosphopyridine nucleotide through the mediation of glutamic acid dehydrogenase and lactic acid dehydrogenase].
    Biochemische Zeitschrift, 1958, Volume: 330, Issue:3

    Topics: Coenzymes; Glutamates; Hydrogen; L-Lactate Dehydrogenase; Lactic Acid; NAD; NADP; Negotiating; Oxidation-Reduction; Oxidoreductases

1958
Lactic dehydrogenase of the mammalian erythrocyte. III. The formation of a complex of the enzyme with DPN and lactate.
    Canadian journal of biochemistry and physiology, 1958, Volume: 36, Issue:10

    Topics: Animals; Biochemical Phenomena; Coenzymes; Erythrocytes; Lactates; Lactic Acid; Mammals; NAD; Oxidoreductases

1958
Evidence for ternary-complex formation with rabbit-muscle lactic acid dehydrogenase, diphosphopyridine nucleotide and pyruvic acid.
    Biochimica et biophysica acta, 1961, Sep-02, Volume: 52

    Topics: Animals; Coenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Muscles; NAD; Oxidoreductases; Pyruvates; Pyruvic Acid; Rabbits

1961
[Effect of vitamin A on the content of pyridine nucleotides, pyruvic and lactic acid and on anaerobic phosphorylation in animal tissues].
    Ukrains'kyi biokhimichnyi zhurnal, 1963, Volume: 35

    Topics: Energy Metabolism; Lactates; Lactic Acid; NAD; Nucleotides; Phosphorylation; Pyridines; Pyruvates; Vitamin A

1963
Levels of soluble NAD-linked alpha-glycerophosphate dehydrogenase and lactic acid dehydrogenase in rat retina.
    Experimental eye research, 1963, Volume: 2

    Topics: Animals; Glycerolphosphate Dehydrogenase; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxidoreductases; Rats; Retina

1963
RESPIRATORY PATHWAYS IN THE MYCOPLASMA. I. LACTATE OXIDATION BY MYCOPLASMA GALLISEPTICUM.
    Journal of bacteriology, 1963, Volume: 86

    Topics: Adenine Nucleotides; Diphosphates; Electron Transport; Flavin Mononucleotide; Flavins; Heme; Lactates; Lactic Acid; Metabolism; Mycoplasma; Mycoplasma gallisepticum; Mycoplasma Infections; NAD; NADH, NADPH Oxidoreductases; Nucleotides; Oxidation-Reduction; Oxidoreductases; Research

1963
[ENZYMATIC CONVERSIONS IN TRITIUM WATER. I. PREPARATION OF SPECIFIC TRITIUM-LABELLED L-LACTIC ACID FROM HTO WITH COUPLED ENZYME REACTIONS].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1963, Volume: 333

    Topics: Biochemical Phenomena; Biochemistry; Lactates; Lactic Acid; NAD; NADP; Research; Tritium; Water

1963
BLOOD LACTATE, PYRUVATE AND LACTATE-PYRUVATE RATIOS IN CONGENITAL HEART DISEASE.
    The New England journal of medicine, 1964, Jun-18, Volume: 270

    Topics: Blood Chemical Analysis; Child; Heart Defects, Congenital; Humans; Hypoxia; Lactates; Lactic Acid; NAD; Oximetry; Pyruvates; Pyruvic Acid

1964
THE DISTRIBUTION OF LACTATE AND NADH TETRAZOLIUM REDUCTASE ACTIVITY IN THE FOETAL HUMAN GASTRIC MUCOSA.
    Acta pathologica et microbiologica Scandinavica, 1964, Volume: 61

    Topics: Dihydrolipoamide Dehydrogenase; Fetus; Gastric Mucosa; Histocytochemistry; Humans; L-Lactate Dehydrogenase; Lactic Acid; NAD; NADH Tetrazolium Reductase; Research; Tetrazolium Salts

1964
[ON THE CONFIGURATION OF LACTATE PRODUCED DURING FERMENTATION OF GLUCOSE BY CERTAIN ENTEROBACTERIA].
    Annales de l'Institut Pasteur, 1964, Volume: 107

    Topics: Carbohydrate Metabolism; Chromatography; Colorimetry; Enterobacter; Enterobacter aerogenes; Enterobacteriaceae; Escherichia; Escherichia coli; Fermentation; Ferrocyanides; Glucose; Klebsiella; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidoreductases; Proteus; Pyruvates; Research; Salmonella typhimurium; Serratia; Spectrophotometry

1964
LACTATE-DEGRADING SYSTEM IN BUTYRIBACTERIUM RETTGERI SUBJECT TO GLUCOSE REPRESSION.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Culture Media; Eubacterium; Fructose; Glucose; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Metabolism; NAD; Oxidation-Reduction; Oxidoreductases; Pyruvates; Pyruvic Acid; Research; Thioctic Acid; United States

1964
PYRUVATE AND LACTATE LEVELS IN RELATIONSHIP TO THE NICOTINAMIDE--ADENINE DINUCLEOTIDE LEVELS IN MALARIAL PARASITES (PLASMODIUM BERGHEI).
    Biochimica et biophysica acta, 1964, Oct-09, Volume: 93

    Topics: Adenine; Animals; Erythrocytes; Glucose; L-Lactate Dehydrogenase; Lactates; Lactic Acid; N-Glycosyl Hydrolases; NAD; Niacinamide; Parasites; Phenylhydrazines; Plasmodium; Plasmodium berghei; Pyruvates; Pyruvic Acid; Rats; Research; Reticulocytes

1964
THE EFFECTS OF X-RADIATION ON LACTATE METABOLISM OF MAMMALIAN CELLS.
    Experimental cell research, 1965, Volume: 37

    Topics: Amines; Carbohydrate Metabolism; Carbon Dioxide; L Cells; Lactates; Lactic Acid; NAD; Niacinamide; Pharmacology; Phosphates; Radiation Effects; Rats; Research; Sodium Chloride; Thymus Gland; Tissue Culture Techniques; X-Rays

1965
A ROUTINE DETERMINATION OF THE OPTICALLY ACTIVE ISOMERS OF LACTIC ACID FOR BACTERIAL CLASSIFICATION.
    Canadian journal of microbiology, 1965, Volume: 11

    Topics: Biochemical Phenomena; Biochemistry; Chromatography; Classification; Colorimetry; Culture Media; Edetic Acid; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lactobacillus; Lactobacillus acidophilus; NAD; Research

1965
[THE ENZYMATIC REGULATION AT THE LACTATE OXIDOREDUCTASE LEVEL. NADH AND NADPH OXIDASES AS WELL AS NADP REACTIVE LACTATE OXIDOREDUCTASE IN RED BLOOD CELLS].
    Acta biologica et medica Germanica, 1964, Volume: 13

    Topics: Animals; Carcinoma, Ehrlich Tumor; Dihydrolipoamide Dehydrogenase; Erythrocytes; Glutathione; Glutathione Reductase; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactates; Lactic Acid; NAD; NADP; NADPH Oxidases; Oxidoreductases; Pyruvates; Rabbits; Reticulocytes

1964
Sepsis-induced failure of hepatic energy metabolism.
    The Journal of surgical research, 2003, Volume: 115, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bacteremia; Blood Flow Velocity; Blood Pressure; Energy Metabolism; Hepatic Artery; Hepatic Veins; Infusions, Intravenous; Lactic Acid; Liver; Male; NAD; Oxygen; Oxygen Consumption; Phosphorylation; Portal Vein; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Shock, Septic; Swine

2003
Significance of phosphoglucose isomerase for the shift between heterolactic and mannitol fermentation of fructose by Oenococcus oeni.
    Archives of microbiology, 2003, Volume: 180, Issue:6

    Topics: Aldehyde-Lyases; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Ethanol; Fermentation; Fructose; Gluconates; Glucose; Glucose-6-Phosphate Isomerase; Gram-Positive Cocci; Lactic Acid; Leuconostoc; Magnetic Resonance Spectroscopy; Mannitol; NAD; NADP; Oxidation-Reduction; Sugar Phosphates

2003
Application of polyaniline/sol-gel derived tetraethylorthosilicate films to an amperometric lactate biosensor.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2003, Volume: 19, Issue:11

    Topics: Aniline Compounds; Biosensing Techniques; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; NAD; Phase Transition; Polyvinyl Chloride; Silanes

2003
NADH augments blood flow in physiologically activated retina and visual cortex.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Jan-13, Volume: 101, Issue:2

    Topics: Animals; Energy Metabolism; Lactic Acid; Male; NAD; NG-Nitroarginine Methyl Ester; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retinal Vessels; Visual Cortex

2004
Structure of Toxoplasma gondii LDH1: active-site differences from human lactate dehydrogenases and the structural basis for efficient APAD+ use.
    Biochemistry, 2004, Feb-03, Volume: 43, Issue:4

    Topics: Animals; Apoenzymes; Binding Sites; Catalysis; Coenzymes; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Muscle, Skeletal; Myocardium; NAD; Oxalic Acid; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyruvic Acid; Substrate Specificity; Toxoplasma

2004
Limited transfer of cytosolic NADH into mitochondria at high cardiac workload.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:6

    Topics: Acetates; Animals; Carbon Isotopes; Coronary Circulation; Cytosol; Dogs; Energy Metabolism; Female; Glutamic Acid; Heart; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Myocardial Contraction; Myocardium; NAD; Oxygen; Succinic Acid

2004
Glycogen metabolism in the rat retina.
    Journal of neurochemistry, 2004, Volume: 88, Issue:4

    Topics: Animals; Darkness; Dose-Response Relationship, Drug; Glucose; Glycogen; In Vitro Techniques; Lactic Acid; Light; NAD; Pyruvic Acid; Rats; Rats, Long-Evans; Retina; Time Factors

2004
Heterogenic response of the liver parenchyma to ethanol studied in the bivascularly perfused rat liver.
    Molecular and cellular biochemistry, 2004, Volume: 258, Issue:1-2

    Topics: Animals; Carbon Dioxide; Citric Acid Cycle; Ethanol; Gluconeogenesis; Glucose; Glycolysis; Lactic Acid; Liver; Liver Glycogen; Male; NAD; Oxidation-Reduction; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Wistar

2004
Regulatory role of lactate in wound repair.
    Methods in enzymology, 2004, Volume: 381

    Topics: Adenosine Diphosphate Ribose; Animals; Collagen; Fibroblasts; Humans; Immunohistochemistry; Lactic Acid; Macrophages; NAD; Neovascularization, Physiologic; Vascular Endothelial Growth Factor A; Wound Healing

2004
Cerebrospinal fluid analysis differentiates multiple system atrophy from Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:5

    Topics: Adult; Aged; Benzamides; Brain; Diagnosis, Differential; Electromyography; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Iodine Radioisotopes; Lactic Acid; Male; Methoxyhydroxyphenylglycol; Multiple System Atrophy; NAD; Parkinson Disease; Pyrrolidines; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2004
Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism.
    Biomedical engineering online, 2004, Jun-02, Volume: 3, Issue:1

    Topics: Adenosine Triphosphate; Glycogen; Glycolysis; Lactic Acid; Models, Cardiovascular; Myocardial Ischemia; Myocardium; NAD; Oxidation-Reduction; Oxygen Consumption; Phosphocreatine; Phosphorylation; Pyruvic Acid

2004
Neuroscience. Let there be (NADH) light.
    Science (New York, N.Y.), 2004, Jul-02, Volume: 305, Issue:5680

    Topics: Animals; Astrocytes; Citric Acid Cycle; Cytoplasm; Dendrites; Fluorescence; Glycolysis; Hippocampus; In Vitro Techniques; Lactic Acid; Microscopy, Confocal; Mitochondria; Models, Neurological; NAD; Neurons; Oxidation-Reduction; Oxidative Phosphorylation; Rats

2004
Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis.
    Science (New York, N.Y.), 2004, Jul-02, Volume: 305, Issue:5680

    Topics: Animals; Astrocytes; Citric Acid Cycle; Cytoplasm; Dendrites; Electron Transport; Fluorescence; Glycolysis; Hippocampus; In Vitro Techniques; Lactic Acid; Mitochondria; NAD; Neurons; Oxidation-Reduction; Oxygen Consumption; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence

2004
A bioelectrochemical polypyrrole-containing Fe(CN)6(3-) interface for the design of a NAD-dependent reagentless biosensor.
    Biosensors & bioelectronics, 2004, Sep-15, Volume: 20, Issue:2

    Topics: Biosensing Techniques; Coated Materials, Biocompatible; Electrochemistry; Electrodes; Equipment Design; Equipment Failure Analysis; Ferricyanides; Indicators and Reagents; Lactate Dehydrogenases; Lactic Acid; NAD; Polymers; Pyrroles; Reproducibility of Results; Sensitivity and Specificity

2004
Too much lactate or too little liver?
    Journal of clinical anesthesia, 2004, Volume: 16, Issue:5

    Topics: Acidosis, Lactic; Adenosine Triphosphate; Aged; Female; Hemofiltration; Humans; Lactic Acid; Liver; Liver Diseases; NAD

2004
Major role of NAD-dependent lactate dehydrogenases in aerobic lactate utilization in Lactobacillus plantarum during early stationary phase.
    Journal of bacteriology, 2004, Volume: 186, Issue:19

    Topics: Acetates; Aerobiosis; Base Sequence; Genes, Bacterial; L-Lactate Dehydrogenase; Lactic Acid; Lactobacillus; Molecular Sequence Data; NAD

2004
Metabolic analysis of Corynebacterium glutamicum during lactate and succinate productions under oxygen deprivation conditions.
    Journal of molecular microbiology and biotechnology, 2004, Volume: 7, Issue:4

    Topics: Acids; Anaerobiosis; Corynebacterium; DNA, Bacterial; Gene Deletion; Gene Dosage; Genes, Bacterial; Glucose; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; NAD; Phosphoenolpyruvate Carboxylase; Pyruvic Acid; Sequence Analysis, DNA; Sodium Bicarbonate; Succinic Acid

2004
Interactions between hyperglycemia and hypoxia: implications for diabetic retinopathy.
    Diabetes, 2004, Volume: 53, Issue:11

    Topics: Animals; Cell Hypoxia; Cornea; Diabetic Retinopathy; Glucose; Hyperglycemia; Lactic Acid; Male; Mitochondria; Models, Biological; NAD; Oxygen Consumption; Pyruvates; Rats; Rats, Sprague-Dawley; Retina

2004
Cytosolic NADH redox and thiol oxidation regulate pulmonary arterial force through ERK MAP kinase.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:6

    Topics: Animals; Cattle; Cell Hypoxia; Cytosol; Diamide; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lactic Acid; Mitogen-Activated Protein Kinases; NAD; NADPH Oxidases; Oxidants; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Artery; Pyruvic Acid; Signal Transduction; Stress, Mechanical; Sulfhydryl Compounds

2005
[Effect of intermittent hypoxic training on indices of adaptation to hypoxia in rats during physical exertion].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2004, Volume: 50, Issue:6

    Topics: Adaptation, Physiological; Animals; Hypoxia; Lactic Acid; Male; Mitochondria, Muscle; Muscle, Skeletal; NAD; Oxidative Phosphorylation; Oxygen Consumption; Physical Exertion; Pyruvic Acid; Rats; Rats, Wistar; Succinate Dehydrogenase

2004
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
    Nature, 2005, Mar-03, Volume: 434, Issue:7029

    Topics: Acetylation; Animals; Caloric Restriction; Cyclic AMP; Fasting; Gene Expression Regulation; Gluconeogenesis; Glucose; Glycolysis; Hepatocytes; Homeostasis; Insulin; Lactic Acid; Liver; Longevity; Lysine; Mice; NAD; Nutritional Status; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Binding; Pyruvic Acid; Rats; RNA, Messenger; Sirtuin 1; Sirtuins; Trans-Activators; Transcription Factors

2005
Pyruvate but not lactate prevents NADH-induced myoglobin oxidation.
    Free radical biology & medicine, 2005, Jun-01, Volume: 38, Issue:11

    Topics: Animals; Antioxidants; Catalase; Dose-Response Relationship, Drug; Free Radicals; Horses; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Myocardium; Myoglobin; NAD; Oxidation-Reduction; Oxygen; Pyruvic Acid; Reperfusion Injury; Time Factors

2005
Interaction between astrocytes and neurons studied using a mathematical model of compartmentalized energy metabolism.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:11

    Topics: Animals; Astrocytes; Brain; Cell Communication; Energy Metabolism; Glucose; Humans; Kinetics; Lactic Acid; Models, Neurological; NAD; Neurons

2005
Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism.
    Journal of neurochemistry, 2005, Volume: 95, Issue:2

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Brain Chemistry; Cells, Cultured; Copper; Electron Transport; Electron Transport Complex IV; Energy Metabolism; Feedback; Heme; Image Processing, Computer-Assisted; Lactic Acid; Microscopy, Confocal; Mitochondria; NAD; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Superoxides

2005
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies.
    The Journal of physiology, 2005, Dec-15, Volume: 569, Issue:Pt 3

    Topics: Animals; Aspartic Acid; Computer Simulation; Cytosol; Energy Metabolism; Glycolysis; Humans; Ischemia; Kinetics; Lactic Acid; Malates; Mitochondria; Models, Biological; Myocardial Ischemia; Myocardium; NAD; Oxidation-Reduction; Oxygen Consumption

2005
Brain lactate kinetics: Modeling evidence for neuronal lactate uptake upon activation.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-08, Volume: 102, Issue:45

    Topics: Animals; Brain; Energy Metabolism; Humans; Hydrogen-Ion Concentration; Lactic Acid; Mathematics; Models, Biological; Monocarboxylic Acid Transporters; NAD; Neurons

2005
Interference and blood sample preparation for a pyruvate enzymatic assay.
    Clinical biochemistry, 2006, Volume: 39, Issue:1

    Topics: Adult; Blood Chemical Analysis; Female; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Middle Aged; NAD; Perchlorates; Pyruvic Acid

2006
The action of extracellular NAD+ on gluconeogenesis in the perfused rat liver.
    Molecular and cellular biochemistry, 2006, Volume: 286, Issue:1-2

    Topics: Acetophenones; Animals; Antioxidants; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gluconeogenesis; Glucose; Indomethacin; Infusion Pumps; Lactic Acid; Liver; Male; Masoprocol; Multivariate Analysis; NAD; Oxygen Consumption; Perfusion; Phospholipases A; Rats; Rats, Wistar; Time Factors

2006
Reexamining the hyperglycemic pseudohypoxia hypothesis of diabetic oculopathy.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:6

    Topics: Adenosine Triphosphate; Aldehyde Reductase; Animals; Cell Culture Techniques; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Epithelial Cells; Glucose; Humans; Hyperglycemia; Hypoxia; Lactic Acid; Lens, Crystalline; NAD; Pigment Epithelium of Eye; Pyruvic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Retina

2006
Insulin-stimulated NADH/NAD+ redox state increases NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells.
    American journal of hypertension, 2006, Volume: 19, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Cell Movement; Cells, Cultured; Drug Synergism; Enzyme Activation; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Muscle, Smooth, Vascular; NAD; NADPH Oxidases; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents

2006
Kinetic analysis of bifidobacterial metabolism reveals a minor role for succinic acid in the regeneration of NAD+ through its growth-associated production.
    Applied and environmental microbiology, 2006, Volume: 72, Issue:8

    Topics: Bifidobacterium; Colony Count, Microbial; Culture Media; Ethanol; Fermentation; Glucose; Industrial Microbiology; Kinetics; Lactic Acid; NAD; Oligosaccharides; Probiotics; Succinic Acid

2006
Molecular basis of substrate recognition in D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida.
    Chembiochem : a European journal of chemical biology, 2006, Volume: 7, Issue:9

    Topics: 3-Hydroxybutyric Acid; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalysis; Computer Simulation; Escherichia coli; Hydrogen Bonding; Hydroxybutyrate Dehydrogenase; Kinetics; Lactic Acid; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Protein Conformation; Pseudomonas putida; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Transfection

2006
Electrochemical biosensor based on integrated assembly of dehydrogenase enzymes and gold nanoparticles.
    Analytical chemistry, 2006, Sep-15, Volume: 78, Issue:18

    Topics: Biosensing Techniques; Electrochemistry; Ethanol; Gold; Hydroxylamine; Lactic Acid; Metal Nanoparticles; NAD; Organosilicon Compounds; Oxidation-Reduction; Oxidoreductases; Silanes

2006
Elevated lactate suppresses neuronal firing in vivo and inhibits glucose metabolism in hippocampal slice cultures.
    Brain research, 2006, Oct-30, Volume: 1117, Issue:1

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Energy Metabolism; Glucose; Hippocampus; Lactic Acid; Male; NAD; Neurons; Organ Culture Techniques; Oxidation-Reduction; Oxidative Phosphorylation; Pyramidal Cells; Pyruvic Acid; Rats; Rats, Long-Evans; Synaptic Transmission; Up-Regulation

2006
Enhanced activity of 3alpha-hydroxysteroid dehydrogenase by addition of the co-solvent 1-butyl-3-methylimidazolium (L)-lactate in aqueous phase of biphasic systems for reductive production of steroids.
    Journal of biotechnology, 2007, Feb-01, Volume: 128, Issue:2

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Androsterone; Formate Dehydrogenases; Hydroxysteroid Dehydrogenases; Ionic Liquids; Lactic Acid; NAD

2007
Endothelial cell response to lactate: implication of PAR modification of VEGF.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Angiogenesis Inducing Agents; Animals; Aorta, Thoracic; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Dose-Response Relationship, Drug; Embryo Culture Techniques; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Humans; Lactic Acid; NAD; Neovascularization, Physiologic; Phenotype; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tissue Culture Techniques; Umbilical Veins; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2007
Regulation of redox metabolism in the mouse oocyte and embryo.
    Development (Cambridge, England), 2007, Volume: 134, Issue:3

    Topics: Animals; Cytosol; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Flavin-Adenine Dinucleotide; Glucose; Glutathione; In Vitro Techniques; Lactic Acid; Mice; Microscopy, Confocal; Mitochondria; Models, Biological; NAD; NADP; Oocytes; Oxidation-Reduction; Pregnancy; Pyruvic Acid

2007
Parallel activation of mitochondrial oxidative metabolism with increased cardiac energy expenditure is not dependent on fatty acid oxidation in pigs.
    The Journal of physiology, 2007, Mar-15, Volume: 579, Issue:Pt 3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Blood Glucose; Blood Pressure; Cardiotonic Agents; Computer Simulation; Coronary Circulation; Dobutamine; Energy Metabolism; Fatty Acids; Glycolysis; Heart Rate; Lactic Acid; Ligation; Mitochondria; Myocardium; NAD; Oxidation-Reduction; Oxygen Consumption; Sus scrofa; Ventricular Pressure

2007
Metabolic engineering of Bacillus subtilis for ethanol production: lactate dehydrogenase plays a key role in fermentative metabolism.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:16

    Topics: Bacillus subtilis; Bacterial Proteins; Butylene Glycols; Ethanol; Fermentation; Gene Deletion; Genes, Bacterial; Genetic Vectors; L-Lactate Dehydrogenase; Lactic Acid; Models, Biological; Models, Genetic; NAD; NADP; Pyruvic Acid

2007
Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity.
    The European journal of neuroscience, 2007, Volume: 26, Issue:8

    Topics: Aconitate Hydratase; Adenosine Triphosphate; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Drug Interactions; Glucose; Hippocampus; Lactic Acid; NAD; Neurons; Organ Culture Techniques; Pyruvic Acid; Rats; Rats, Wistar; Time Factors

2007
Transport and metabolism of L-lactate occur in mitochondria from cerebellar granule cells and are modified in cells undergoing low potassium dependent apoptosis.
    Biochimica et biophysica acta, 2007, Volume: 1767, Issue:11

    Topics: Animals; Apoptosis; Biological Transport; Blotting, Western; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Glucose; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Mitochondria; Models, Biological; NAD; Oxidation-Reduction; Oxygen Consumption; Potassium; Rats; Rats, Wistar

2007
Effects of nicotinamide adenine dinucleotide hydride on physical and mental performance.
    Journal of sports sciences, 2008, Feb-01, Volume: 26, Issue:3

    Topics: Austria; Cognition; Creatine Kinase; Cross-Over Studies; Double-Blind Method; Exercise Test; Humans; Lactic Acid; Male; NAD; Oxygen Consumption; Placebos

2008
Effect of alternate energy substrates on mammalian brain metabolism during ischemic events.
    Advances in experimental medicine and biology, 2008, Volume: 614

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Computational Biology; Energy Metabolism; Lactic Acid; Mammals; Models, Neurological; NAD; Neurons; Phosphorus; Reproducibility of Results; Substrate Specificity

2008
Immobilization enzyme fluorescence capillary analysis for determination of lactic acid.
    Analytica chimica acta, 2008, Mar-10, Volume: 610, Issue:2

    Topics: Bioreactors; Enzymes, Immobilized; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; NAD; Sensitivity and Specificity; Spectrometry, Fluorescence

2008
The action of extracellular NAD+ in the liver of healthy and tumor-bearing rats: model analysis of the tumor-induced modified response.
    Experimental and molecular pathology, 2008, Volume: 84, Issue:3

    Topics: Animals; Cachexia; Carcinoma 256, Walker; Eicosanoids; Extracellular Fluid; Glucose; Hemodynamics; Indomethacin; Lactic Acid; Liver; Male; Models, Biological; NAD; Oxygen Consumption; Protein Synthesis Inhibitors; Pyruvic Acid; Rats; Rats, Wistar

2008
Probing the role of dynamics in hydride transfer catalyzed by lactate dehydrogenase.
    Biophysical journal, 2008, Volume: 95, Issue:4

    Topics: Catalysis; Computer Simulation; Enzyme Activation; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Light; Models, Chemical; Models, Molecular; NAD; Pyruvic Acid

2008
Transformation and actions of extracellular NADP(+) in the rat liver.
    Molecular and cellular biochemistry, 2008, Volume: 317, Issue:1-2

    Topics: Animals; Chromatography, High Pressure Liquid; Extracellular Space; Glucose; Lactic Acid; Liver; Liver Glycogen; Male; Models, Biological; NAD; NAD+ Nucleosidase; NADP; Oxygen; Perfusion; Portal Vein; Rats; Rats, Wistar; Time Factors

2008
Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies.
    American journal of physiology. Cell physiology, 2009, Volume: 296, Issue:1

    Topics: Biological Transport; Computer Simulation; Cytosol; Energy Metabolism; Exercise; Glycogen; Humans; Ischemia; Kinetics; Lactic Acid; Mitochondria, Muscle; Models, Biological; Muscle, Skeletal; NAD; Oxidation-Reduction; Oxygen Consumption; Recovery of Function; Regional Blood Flow; Reproducibility of Results

2009
A lactate biosensor based on lactate dehydrogenase/nictotinamide adenine dinucleotide (oxidized form) immobilized on a conducting polymer/multiwall carbon nanotube composite film.
    Analytical biochemistry, 2009, Jan-01, Volume: 384, Issue:1

    Topics: Biosensing Techniques; Calibration; Enzymes, Immobilized; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Models, Biological; NAD; Nanotubes, Carbon; Oxidation-Reduction; Polymers; Reproducibility of Results; Temperature

2009
Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver.
    Biogerontology, 2009, Volume: 10, Issue:4

    Topics: Age Factors; Aging; Aldehyde Reductase; Animals; Caloric Restriction; Fructose; Glucose; L-Iditol 2-Dehydrogenase; Lactic Acid; Liver; Malates; Male; Mice; Mice, Inbred C57BL; NAD; NADP; Oxidation-Reduction; Pyruvic Acid; Sorbitol

2009
Nanoparticle-supported multi-enzyme biocatalysis with in situ cofactor regeneration.
    Journal of biotechnology, 2009, Jan-01, Volume: 139, Issue:1

    Topics: Animals; Biocatalysis; Cattle; Coenzymes; Enzymes, Immobilized; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Motion; NAD; Nanoparticles; Pyruvic Acid; Rabbits; Silicon Dioxide

2009
Non-sterilized fermentative production of polymer-grade L-lactic acid by a newly isolated thermophilic strain Bacillus sp. 2-6.
    PloS one, 2009, Volume: 4, Issue:2

    Topics: Bacillus; Bioreactors; Culture Media; Fermentation; Glucose; L-Lactate Dehydrogenase; Lactic Acid; NAD; Nitrogen; Polymers; Sterilization; Temperature

2009
Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite.
    Malaria journal, 2009, Mar-06, Volume: 8

    Topics: Alanine; Anaerobiosis; Animals; Energy Metabolism; Glucose; Glycerol; Humans; Lactic Acid; NAD; Oxidation-Reduction; Plasmodium falciparum; Pyruvic Acid; Spectrum Analysis

2009
Physiologically relevant online electrochemical method for continuous and simultaneous monitoring of striatum glucose and lactate following global cerebral ischemia/reperfusion.
    Analytical chemistry, 2009, Mar-15, Volume: 81, Issue:6

    Topics: Animals; Biosensing Techniques; Brain Ischemia; Carbon; Corpus Striatum; Electrochemical Techniques; Electrodes; Glucose; Glucose Dehydrogenases; Hydrogen-Ion Concentration; Lactate Dehydrogenases; Lactic Acid; Male; Methylene Blue; NAD; Nanotubes, Carbon; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2009
Effect of succinate sodium on the metmyoglobin reduction and color stability of beef patties.
    Journal of agricultural and food chemistry, 2009, Jul-08, Volume: 57, Issue:13

    Topics: Animals; Cattle; Color; Dose-Response Relationship, Drug; Food Preservation; Lactic Acid; Meat; Metmyoglobin; Mitochondria; NAD; Oxidation-Reduction; Succinic Acid

2009
Metabolism in 1,3-propanediol fed-batch fermentation by a D-lactate deficient mutant of Klebsiella pneumoniae.
    Biotechnology and bioengineering, 2009, Dec-01, Volume: 104, Issue:5

    Topics: Bacterial Proteins; Fermentation; Gene Knockout Techniques; Glycerol; Klebsiella pneumoniae; L-Lactate Dehydrogenase; Lactic Acid; NAD; Propylene Glycols

2009
Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype.
    Molecular cancer, 2009, Jul-31, Volume: 8

    Topics: Adenovirus E1A Proteins; Animals; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Glycolysis; Lactic Acid; Male; Metabolome; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Scanning; Mitochondria; NAD; Neoplasm Transplantation; Neoplasms, Experimental; Oxidative Phosphorylation; Oxygen Consumption; ras Proteins; Retroviridae; Superoxides

2009
Characterization of the L-lactate dehydrogenase from Aggregatibacter actinomycetemcomitans.
    PloS one, 2009, Nov-17, Volume: 4, Issue:11

    Topics: Bacterial Proteins; Biological Transport; Carbon; Gene Expression Regulation, Enzymologic; Glucose; Gram-Negative Bacteria; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Biological; NAD; Protein Structure, Tertiary; Pyruvic Acid

2009
NADH-generating substrates reduce peroxyl radical toxicity in RL-34 cells.
    Folia morphologica, 2009, Volume: 68, Issue:4

    Topics: Acetoacetates; Alcohols; Amidines; Animals; Apoptosis; Cell Line; Cell Survival; Ethanol; Fluoresceins; Hydroxybutyrates; Lactic Acid; Liver; NAD; Oxidative Stress; Peroxides; Rats; Reactive Oxygen Species

2009
Structure of D-lactate dehydrogenase from Aquifex aeolicus complexed with NAD(+) and lactic acid (or pyruvate).
    Acta crystallographica. Section F, Structural biology and crystallization communications, 2009, Dec-01, Volume: 65, Issue:Pt 12

    Topics: Bacteria; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Genes, Bacterial; Lactate Dehydrogenases; Lactic Acid; Lactobacillus helveticus; Models, Molecular; NAD; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Pyruvic Acid; Recombinant Proteins; Static Electricity

2009
Lactate formation in Caldicellulosiruptor saccharolyticus is regulated by the energy carriers pyrophosphate and ATP.
    Metabolic engineering, 2010, Volume: 12, Issue:3

    Topics: Carbon; Diphosphates; Glucose; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Physical Phenomena

2010
Energy restriction as an antitumor target of thiazolidinediones.
    The Journal of biological chemistry, 2010, Mar-26, Volume: 285, Issue:13

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Proliferation; Glucose; Glycolysis; Humans; Lactic Acid; Microscopy, Fluorescence; NAD; Neoplasms; PPAR gamma; Signal Transduction; Thiazolidinediones

2010
L-lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative L-lactate oxidase localized in the intermembrane space.
    FEBS letters, 2010, Jun-03, Volume: 584, Issue:11

    Topics: Animals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Intracellular Membranes; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria; Mitochondria, Liver; Mixed Function Oxygenases; NAD; Oxidants; Pyruvic Acid; Rats; Rats, Wistar

2010
Myoglobin redox form stabilization by compartmentalized lactate and malate dehydrogenases.
    Journal of agricultural and food chemistry, 2010, Jun-09, Volume: 58, Issue:11

    Topics: Animals; Cattle; Cytoplasm; Enzyme Stability; Horses; Lactic Acid; Malate Dehydrogenase; Mitochondria; Muscle, Skeletal; Myoglobin; NAD; Oxidation-Reduction; Substrate Specificity

2010
Optical detection of single cell lactate release for cancer metabolic analysis.
    Analytical chemistry, 2010, Jun-15, Volume: 82, Issue:12

    Topics: Biosensing Techniques; Calibration; Cell Line, Tumor; Humans; L-Lactate Dehydrogenase; Lactic Acid; NAD; Neoplasms; Optical Fibers

2010
Effects of oxygen on Shewanella decolorationis NTOU1 electron transfer to carbon-felt electrodes.
    Biosensors & bioelectronics, 2010, Aug-15, Volume: 25, Issue:12

    Topics: Aerobiosis; Ammonia; Anaerobiosis; Bioelectric Energy Sources; Biosensing Techniques; Chromatography, High Pressure Liquid; Electrochemical Techniques; Electron Transport; Lactic Acid; NAD; Oxidation-Reduction; Oxygen; Shewanella

2010
Amperometric lactate biosensor for flow injection analysis based on a screen-printed carbon electrode containing Meldola's Blue-Reinecke salt, coated with lactate dehydrogenase and NAD+.
    Talanta, 2010, Jun-30, Volume: 82, Issue:1

    Topics: Animals; Biosensing Techniques; Carbon; Cattle; Electrochemistry; Electrodes; Flow Injection Analysis; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxazines; Printing; Swine; Thiocyanates

2010
The biphasic NAD(P)H fluorescence response of astrocytes to dopamine reflects the metabolic actions of oxidative phosphorylation and glycolysis.
    Journal of neurochemistry, 2010, Volume: 115, Issue:2

    Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Colforsin; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fluorescence; Glial Fibrillary Acidic Protein; Glucose; Glycolysis; Green Fluorescent Proteins; In Vitro Techniques; Lactic Acid; Mice; Mice, Transgenic; Microscopy, Confocal; NAD; Oxidative Phosphorylation; Signal Transduction; Time Factors

2010
Enzymatic synthesis of L-lactic acid from carbon dioxide and ethanol with an inherent cofactor regeneration cycle.
    Biotechnology and bioengineering, 2011, Volume: 108, Issue:2

    Topics: Bioreactors; Biotechnology; Carbon Dioxide; Coenzymes; Ethanol; Kinetics; Lactic Acid; Multienzyme Complexes; NAD

2011
Stimulation of reductive glycerol metabolism by overexpression of an aldehyde dehydrogenase in a recombinant Klebsiella pneumoniae strain defective in the oxidative pathway.
    Journal of industrial microbiology & biotechnology, 2011, Volume: 38, Issue:8

    Topics: Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Amino Acid Sequence; Biofuels; Biotechnology; Fermentation; Glycerol; Klebsiella pneumoniae; Lactic Acid; Molecular Sequence Data; NAD; Oxidation-Reduction; Sugar Alcohol Dehydrogenases

2011
Elimination of D-lactate synthesis increases poly(3-hydroxybutyrate) and ethanol synthesis from glycerol and affects cofactor distribution in recombinant Escherichia coli.
    Applied and environmental microbiology, 2010, Volume: 76, Issue:22

    Topics: Biomass; Bioreactors; Carbon; Escherichia coli; Ethanol; Glycerol; Hydroxybutyrates; Lactate Dehydrogenases; Lactic Acid; Metabolic Networks and Pathways; NAD; NADP; Polyesters; Time Factors

2010
Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.
    Molecular genetics and genomics : MGG, 2010, Volume: 284, Issue:6

    Topics: Aspergillus nidulans; Base Sequence; Citric Acid Cycle; DNA Primers; Ethanol; gamma-Aminobutyric Acid; Gene Expression; Gene Expression Profiling; Genes, Fungal; Glutamic Acid; Glycolysis; Lactic Acid; Metabolic Networks and Pathways; NAD; Oxygen; Protein Array Analysis; Transcription, Genetic

2010
Identification and characterization of the propanediol utilization protein PduP of Lactobacillus reuteri for 3-hydroxypropionic acid production from glycerol.
    Applied microbiology and biotechnology, 2011, Volume: 89, Issue:3

    Topics: Aldehydes; Bacterial Proteins; Cloning, Molecular; Coenzymes; Enzymes; Gene Expression; Glycerol; Kinetics; Klebsiella pneumoniae; Lactic Acid; Limosilactobacillus reuteri; NAD; NADP; Recombinant Proteins; Substrate Specificity

2011
A new scheme to calculate isotope effects.
    Journal of molecular modeling, 2011, Volume: 17, Issue:9

    Topics: Algorithms; Biocatalysis; Catalytic Domain; Computer Simulation; Hydrogen Bonding; Isotopes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Models, Molecular; NAD; Oxamic Acid; Pyruvic Acid

2011
L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase.
    International journal of oncology, 2010, Volume: 37, Issue:6

    Topics: Carcinoma; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria; Mitochondrial Swelling; NAD; Oxygen; Oxygen Consumption; Prostate; Prostatic Neoplasms; Pyruvic Acid

2010
Ethanol and psychotropic drug interaction during pregnancy and lactation.
    Biochemical pharmacology, 1981, Sep-01, Volume: 30, Issue:17

    Topics: Alcohol Dehydrogenase; Animals; Animals, Newborn; Central Nervous System Depressants; Chlorpromazine; Enzyme Inhibitors; Ethanol; Female; Lactation; Lactic Acid; Liver; Maternal Exposure; NAD; Pregnancy; Psychotropic Drugs; Pyrazoles; Rats; Uridine Diphosphate Glucose; Uridine Diphosphate Glucuronic Acid

1981
Characterization of lactate dehydrogenase enzyme in seminal plasma of Japanese quail (Coturnix coturnix japonica).
    Theriogenology, 2011, Volume: 75, Issue:3

    Topics: Animals; Coturnix; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Male; NAD; Pyruvic Acid; Semen; Spermatozoa; Urea

2011
Disruption of pyridine nucleotide redox status during oxidative challenge at normal and low-glucose states: implications for cellular adenosine triphosphate, mitochondrial respiratory activity, and reducing capacity in colon epithelial cells.
    Antioxidants & redox signaling, 2011, Volume: 14, Issue:11

    Topics: Adenosine Triphosphate; Cell Respiration; Colon; Cytoplasm; Enzyme Assays; Epithelial Cells; Glucose; Glutathione; Glutathione Disulfide; Homeostasis; HT29 Cells; Humans; Intestinal Mucosa; Lactic Acid; Mitochondria; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Vitamin K 3

2011
Synechococcus sp. strain PCC 7002 nifJ mutant lacking pyruvate:ferredoxin oxidoreductase.
    Applied and environmental microbiology, 2011, Volume: 77, Issue:7

    Topics: Acetates; Darkness; Fermentation; Gene Knockout Techniques; Hydrogen; Lactic Acid; Light; NAD; Oxidation-Reduction; Pyruvate Synthase; Pyruvic Acid; Synechococcus

2011
Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
    Journal of medicinal chemistry, 2011, Mar-24, Volume: 54, Issue:6

    Topics: Antineoplastic Agents; Cell Cycle; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Glucose; Humans; Indoles; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Models, Molecular; NAD; Pyruvic Acid; Structure-Activity Relationship; Substrate Specificity

2011
NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels.
    PloS one, 2011, Mar-31, Volume: 6, Issue:3

    Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Line, Tumor; Cells, Cultured; Female; HEK293 Cells; Hep G2 Cells; Humans; Lactic Acid; Male; Membrane Potential, Mitochondrial; Mice; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Quinones; Rats; Rotenone; Ubiquinone

2011
Efficient conversion of phenylpyruvic acid to phenyllactic acid by using whole cells of Bacillus coagulans SDM.
    PloS one, 2011, Apr-20, Volume: 6, Issue:4

    Topics: Bacillus; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; NAD; Phenylpyruvic Acids; Substrate Specificity

2011
Kinetic characterisation of recombinant Corynebacterium glutamicum NAD+-dependent LDH over-expressed in E. coli and its rescue of an lldD- phenotype in C. glutamicum: the issue of reversibility re-examined.
    Archives of microbiology, 2011, Volume: 193, Issue:10

    Topics: Bacterial Proteins; Cloning, Molecular; Corynebacterium glutamicum; Enzyme Activation; Escherichia coli; Fructosediphosphates; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Mutation; NAD; Open Reading Frames; Oxidation-Reduction; Pyruvic Acid; Recombinant Proteins

2011
Influence of tamoxifen on gluconeogenesis and glycolysis in the perfused rat liver.
    Chemico-biological interactions, 2011, Aug-15, Volume: 193, Issue:1

    Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Fructose; Fructose-Bisphosphatase; Fumarate Hydratase; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Glycogen; Glycolysis; Lactate Dehydrogenases; Lactic Acid; Liver; Male; NAD; Nitric Oxide; Phosphoenolpyruvate Carboxykinase (ATP); Pyruvate Carboxylase; Rats; Rats, Wistar; Tamoxifen

2011
Free [NADH]/[NAD(+)] regulates sirtuin expression.
    Archives of biochemistry and biophysics, 2011, Aug-01, Volume: 512, Issue:1

    Topics: Animals; Cells, Cultured; Drosophila melanogaster; Ethanol; Fibroblasts; Gene Expression Regulation; Lactic Acid; Male; Mice; NAD; NIH 3T3 Cells; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Pyruvic Acid; Rats; Rats, Wistar; RNA, Messenger; Sirtuins; Trans-Activators; Transcription Factors

2011
Impact of high pyruvate concentration on kinetics of rabbit muscle lactate dehydrogenase.
    Applied biochemistry and biotechnology, 2011, Volume: 165, Issue:2

    Topics: Animals; Feedback, Physiological; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Muscles; NAD; Pyruvic Acid; Rabbits; Software; Spectrophotometry

2011
Increased furfural tolerance due to overexpression of NADH-dependent oxidoreductase FucO in Escherichia coli strains engineered for the production of ethanol and lactate.
    Applied and environmental microbiology, 2011, Volume: 77, Issue:15

    Topics: Alcohol Oxidoreductases; Escherichia coli; Escherichia coli Proteins; Ethanol; Fermentation; Furaldehyde; Genetic Engineering; Lactic Acid; NAD; NADH, NADPH Oxidoreductases; Oxidoreductases; Xylose

2011
Roles of glucose in photoreceptor survival.
    The Journal of biological chemistry, 2011, Oct-07, Volume: 286, Issue:40

    Topics: Acetylglucosamine; Adenosine Triphosphate; Animals; Autophagy; Cell Death; Cell Survival; Gas Chromatography-Mass Spectrometry; Glucose; Lactic Acid; Mice; Mice, Inbred C57BL; Mitochondria; NAD; Neurodegenerative Diseases; Neurons; Oxygen Consumption; Photoreceptor Cells, Vertebrate; Retina

2011
Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells.
    Molecular and cellular biology, 2011, Volume: 31, Issue:24

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Glycolysis; Homeostasis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Mice; Mice, Nude; Mitochondria; NAD; Neoplasms; Oxidation-Reduction; Phosphorylation; Receptor, Fibroblast Growth Factor, Type 1; Tyrosine

2011
Genetically encoded fluorescent sensors for intracellular NADH detection.
    Cell metabolism, 2011, Oct-05, Volume: 14, Issue:4

    Topics: Bacterial Proteins; Cell Line; Cytosol; Glucose; Humans; Hydrogen Peroxide; Lactic Acid; Luminescent Proteins; Microscopy, Fluorescence; Mitochondria; NAD; Oxidation-Reduction; Pyruvic Acid

2011
Adult body weight is programmed by a redox-regulated and energy-dependent process during the pronuclear stage in mouse.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Animals; Body Weight; Energy Metabolism; Lactic Acid; Mice; Mitochondria; NAD; Oxidation-Reduction; Oxidative Phosphorylation

2011
Low potential detection of NADH based on Fe₃O₄ nanoparticles/multiwalled carbon nanotubes composite: fabrication of integrated dehydrogenase-based lactate biosensor.
    Biosensors & bioelectronics, 2012, Mar-15, Volume: 33, Issue:1

    Topics: Biosensing Techniques; Electrochemical Techniques; Ferric Compounds; Humans; L-Lactate Dehydrogenase; Lactic Acid; Metal Nanoparticles; NAD; Nanotubes, Carbon

2012
A mutant in the ADH1 gene of Chlamydomonas reinhardtii elicits metabolic restructuring during anaerobiosis.
    Plant physiology, 2012, Volume: 158, Issue:3

    Topics: Acetate Kinase; Acetates; Acetyltransferases; Alcohol Dehydrogenase; Anaerobiosis; Blotting, Western; Carbon Dioxide; Chlamydomonas reinhardtii; Ethanol; Fermentation; Formates; Genes, Plant; Glycerol; Hydrogen; Lactic Acid; Metabolome; NAD; Plant Proteins; Pyruvate Synthase; Transcription, Genetic

2012
Ca²⁺ signals of astrocytes are modulated by the NAD⁺/NADH redox state.
    Journal of neurochemistry, 2012, Volume: 120, Issue:6

    Topics: Animals; Astrocytes; Benzazepines; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Glucose; Isoquinolines; Lactic Acid; Mice; Mice, Inbred C57BL; NAD; Oxidation-Reduction; Protein Kinase Inhibitors; Pyruvic Acid; Sulfonamides

2012
Micro-coulometric study of bioelectrochemical reaction coupled with TCA cycle.
    Biosensors & bioelectronics, 2012, Apr-15, Volume: 34, Issue:1

    Topics: Acetyl Coenzyme A; Biosensing Techniques; Catalysis; Citric Acid Cycle; Electrochemical Techniques; Electrodes; Electrolysis; Lactic Acid; NAD; NADH Dehydrogenase; Oxidation-Reduction; Succinate Dehydrogenase

2012
Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells.
    Journal of neural transmission (Vienna, Austria : 1996), 2012, Volume: 119, Issue:11

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antipsychotic Agents; Apoptosis; Aripiprazole; Carbon; Cell Survival; Clozapine; Dihydrolipoamide Dehydrogenase; Dose-Response Relationship, Drug; Electron Transport Complex IV; Extracellular Fluid; Gene Expression Regulation, Enzymologic; Glucose; Glycolysis; Hypoxanthine Phosphoribosyltransferase; Isocitrate Dehydrogenase; Ketone Oxidoreductases; Lactic Acid; Membrane Potential, Mitochondrial; NAD; Oxidoreductases; PC12 Cells; Piperazines; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Quinolones; Rats; RNA, Messenger; Time Factors

2012
Metabolic consequences of NDUFS4 gene deletion in immortalized mouse embryonic fibroblasts.
    Biochimica et biophysica acta, 2012, Volume: 1817, Issue:10

    Topics: Adenosine Triphosphate; Animals; Cell Line, Transformed; Electron Transport Complex I; Embryo, Mammalian; Enzyme Stability; Fibroblasts; Gene Deletion; Humans; Lactic Acid; Mice; Mice, Knockout; Mitochondria; Mitochondrial Proteins; NAD; NADP; Phosphorylation; Proton-Translocating ATPases; Pyruvate Dehydrogenase Complex

2012
Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:6

    Topics: Acute Disease; Adenosine Triphosphate; Animals; Cell Death; Diabetic Neuropathies; Electrocardiography; Glycolysis; Hippocampus; Hydrogen-Ion Concentration; Hypoglycemia; Lactic Acid; Male; NAD; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley

2012
Fine tuning of the lactate and diacetyl production through promoter engineering in Lactococcus lactis.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Base Sequence; Cell Survival; Diacetyl; Genetic Engineering; Hydrogen Peroxide; Intracellular Space; Lactic Acid; Lactococcus lactis; Molecular Sequence Data; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Promoter Regions, Genetic

2012
Biochemical issues in estimation of cytosolic free NAD/NADH ratio.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Cell Line, Tumor; Cytosol; Humans; Lactic Acid; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates

2012
NAD-independent L-lactate dehydrogenase is required for L-lactate utilization in Pseudomonas stutzeri SDM.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Amino Acid Sequence; Coenzymes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; Mutation; NAD; Pseudomonas stutzeri; Sequence Analysis

2012
Role of hyperglycemia-mediated erythrocyte redox state alteration in the development of diabetic retinopathy.
    Retina (Philadelphia, Pa.), 2013, Volume: 33, Issue:1

    Topics: Blood Glucose; Blood Pressure; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Erythrocyte Membrane; Erythrocytes; Female; Fluorescein Angiography; Glucose Tolerance Test; Glutathione; Glycated Hemoglobin; Humans; Hyperglycemia; Lactic Acid; Male; Middle Aged; NAD; NADP; Oxidation-Reduction; Pyruvic Acid

2013
Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Jun-27, Volume: 32, Issue:26

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine Triphosphate; Animals; Animals, Newborn; Cadmium Chloride; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycolysis; Hippocampus; In Vitro Techniques; Lactic Acid; Models, Biological; NAD; Neurons; Organic Chemicals; Oxidative Phosphorylation; Oxygen; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Statistics, Nonparametric; Synapses; Tetrodotoxin; Valine

2012
Online enzyme discrimination and determination of substrate enantiomers based on electrophoretically mediated microanalysis.
    Analytical chemistry, 2012, Aug-07, Volume: 84, Issue:15

    Topics: Electrophoresis, Capillary; Enzyme Assays; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; NAD; Spectrophotometry, Ultraviolet; Stereoisomerism; Substrate Specificity; Wine; Yogurt

2012
Presence of bound substrate in lactate dehydrogenase from carp liver.
    Indian journal of biochemistry & biophysics, 2012, Volume: 49, Issue:3

    Topics: Animals; Carps; Chromatography, Gel; Enzyme Stability; L-Lactate Dehydrogenase; Lactic Acid; Liver; Mass Spectrometry; NAD; Pyruvic Acid; UDPglucose 4-Epimerase

2012
Increased oxidative stress and anaerobic energy release, but blunted Thr172-AMPKα phosphorylation, in response to sprint exercise in severe acute hypoxia in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 113, Issue:6

    Topics: Acute Disease; Adult; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Anaerobic Threshold; Biopsy; Blood Glucose; Blood Proteins; Energy Metabolism; Exercise; Exercise Test; GTPase-Activating Proteins; Humans; Hypoxia; Insulin; Lactic Acid; Male; Muscle Contraction; Muscle Strength; NAD; Oxidative Stress; Oxygen Consumption; Phosphorylation; Protein Carbonylation; Protein Serine-Threonine Kinases; Quadriceps Muscle; Running; Severity of Illness Index; Sirtuin 1; Threonine; Time Factors; Young Adult

2012
Glucose is a pH-dependent motor for sperm beat frequency during early activation.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Carbonic Anhydrases; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Energy Metabolism; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Male; Methylamines; Mice; Mitochondria; NAD; NADP; Propionates; Pyruvic Acid; Sperm Motility; Spermatozoa; Succinic Acid

2012
Metabolic master regulators: sharing information among multiple systems.
    Trends in endocrinology and metabolism: TEM, 2012, Volume: 23, Issue:12

    Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Insulin Resistance; Lactic Acid; Liver; Metabolome; Mitochondria; Models, Biological; Muscles; NAD; NADP; Obesity; Oxidation-Reduction; Pyruvic Acid; Signal Transduction

2012
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes.
    Neurochemistry international, 2012, Volume: 61, Issue:8

    Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cell Separation; Cells, Cultured; Cellular Senescence; Cytoplasm; Energy Metabolism; Female; Glutamic Acid; Lactic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; NAD; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Primary Cell Culture; Pyruvic Acid; Real-Time Polymerase Chain Reaction; RNA, Messenger

2012
Determinants of brain cell metabolic phenotypes and energy substrate utilization unraveled with a modeling approach.
    PLoS computational biology, 2012, Volume: 8, Issue:9

    Topics: Animals; Brain; Computer Simulation; Energy Metabolism; Humans; Lactic Acid; Models, Neurological; NAD; Neurons; Pyruvate Dehydrogenase Complex

2012
Manipulation of the anoxic metabolism in Escherichia coli by ArcB deletion variants in the ArcBA two-component system.
    Applied and environmental microbiology, 2012, Volume: 78, Issue:24

    Topics: Anaerobiosis; Bacterial Outer Membrane Proteins; Escherichia coli; Escherichia coli Proteins; Ethanol; Fermentation; Glucose; Lactic Acid; Membrane Proteins; Metabolic Networks and Pathways; NAD; Protein Kinases; Repressor Proteins; Sequence Deletion; Succinic Acid

2012
A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2012, Volume: 225

    Topics: Adenocarcinoma; Algorithms; Animals; Electromagnetic Fields; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolism; Mice; Mice, Transgenic; NAD; Prostatic Neoplasms; Pyruvic Acid; Radio Waves; Tissue Distribution

2012
Effect of ouabain on metabolic oxidative state in living cardiomyocytes evaluated by time-resolved spectroscopy of endogenous NAD(P)H fluorescence.
    Journal of biomedical optics, 2012, Volume: 17, Issue:10

    Topics: Animals; Cardiotonic Agents; Female; Lactic Acid; Mitochondria; Myocytes, Cardiac; NAD; NADP; Ouabain; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence

2012
Engineering of Corynebacterium glutamicum for high-yield L-valine production under oxygen deprivation conditions.
    Applied and environmental microbiology, 2013, Volume: 79, Issue:4

    Topics: Anaerobiosis; Biosynthetic Pathways; Corynebacterium glutamicum; Gene Deletion; Gene Expression; Lactic Acid; Metabolic Engineering; NAD; Oxygen; Recombination, Genetic; Succinic Acid; Valine

2013
Critical role for free radicals on sprint exercise-induced CaMKII and AMPKα phosphorylation in human skeletal muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Mar-01, Volume: 114, Issue:5

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adult; AMP-Activated Protein Kinases; Antioxidants; Blood Glucose; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Double-Blind Method; Exercise; Free Radicals; Humans; Insulin; Lactic Acid; Male; Muscle, Skeletal; NAD; Oxygen Consumption; Phosphorylation; Reactive Nitrogen Species; Reactive Oxygen Species; Respiration

2013
Identification and characterization of Klebsiella pneumoniae aldehyde dehydrogenases increasing production of 3-hydroxypropionic acid from glycerol.
    Bioprocess and biosystems engineering, 2013, Volume: 36, Issue:9

    Topics: Aldehyde Dehydrogenase; Bacterial Proteins; Coenzymes; Glycerol; Klebsiella pneumoniae; Lactic Acid; NAD; NADP; Oxidation-Reduction; Recombinant Proteins

2013
Intracellular NAD(H) levels control motility and invasion of glioma cells.
    Cellular and molecular life sciences : CMLS, 2013, Volume: 70, Issue:12

    Topics: Blotting, Northern; Blotting, Western; Cell Movement; Gene Expression Regulation, Neoplastic; Glioma; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; NAD; Neoplasm Invasiveness; Nicotinamide Phosphoribosyltransferase; Time-Lapse Imaging; Tumor Cells, Cultured

2013
Bovine mitochondrial oxygen consumption effects on oxymyoglobin in the presence of lactate as a substrate for respiration.
    Meat science, 2013, Volume: 93, Issue:4

    Topics: Animals; Antimycin A; Cattle; Cell Respiration; L-Lactate Dehydrogenase; Lactic Acid; Meat; Mitochondria; Mitochondria, Heart; Muscle, Skeletal; Muscles; Myocardium; Myoglobin; NAD; Oxidation-Reduction; Oxygen Consumption

2013
D-Lactate production as a function of glucose metabolism in Saccharomyces cerevisiae.
    Yeast (Chichester, England), 2013, Volume: 30, Issue:2

    Topics: Aerobiosis; Computer Simulation; Culture Media; Glucose; Lactic Acid; NAD; Pyruvaldehyde; Saccharomyces cerevisiae; Trioses

2013
Lactate oxidation in human skeletal muscle mitochondria.
    American journal of physiology. Endocrinology and metabolism, 2013, Apr-01, Volume: 304, Issue:7

    Topics: Cell Respiration; Female; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; NAD; Oxidation-Reduction; Pyruvic Acid

2013
Nanoparticle-tethered NAD(+) with in situ cofactor regeneration.
    Biotechnology letters, 2013, Volume: 35, Issue:6

    Topics: Alcohol Oxidoreductases; Coenzymes; Formate Dehydrogenases; Formates; Lactic Acid; NAD; Nanoparticles; Propylamines; Pyruvic Acid; Silanes; Silicon Dioxide

2013
Utilization of Saccharomyces cerevisiae recombinant strain incapable of both ethanol and glycerol biosynthesis for anaerobic bioproduction.
    Applied microbiology and biotechnology, 2013, Volume: 97, Issue:11

    Topics: Anaerobiosis; Ethanol; Gene Knockout Techniques; Glycerol; Lactic Acid; Metabolic Engineering; Metabolic Networks and Pathways; NAD; Oxidation-Reduction; Saccharomyces cerevisiae

2013
Purification and properties of a monomeric lactate dehydrogenase from yak Hypoderma sinense larva.
    Experimental parasitology, 2013, Volume: 134, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; China; Chromatography, Affinity; Chromatography, Gel; Diptera; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Larva; Mercuric Chloride; Molecular Weight; Myiasis; NAD; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyruvates; Temperature

2013
Fe3O4 magnetic nanoparticles/reduced graphene oxide nanosheets as a novel electrochemical and bioeletrochemical sensing platform.
    Biosensors & bioelectronics, 2013, Nov-15, Volume: 49

    Topics: Ascorbic Acid; Biosensing Techniques; Dopamine; Electrochemical Techniques; Ferric Compounds; Graphite; Hydrogen Peroxide; Lactic Acid; Magnetite Nanoparticles; NAD; Nanocomposites; Nitrites; Oxidation-Reduction; Oxides; Oxygen; Sensitivity and Specificity; Uric Acid

2013
Disturbance of aerobic metabolism accompanies neurobehavioral changes induced by nickel in mice.
    Neurotoxicology, 2013, Volume: 38

    Topics: Aconitate Hydratase; Adenosine Triphosphate; Aerobiosis; Animals; Brain; Cerebral Cortex; Down-Regulation; Exploratory Behavior; Iron-Sulfur Proteins; Lactic Acid; Male; Maze Learning; Mice; NAD; Nickel; Oxidative Stress; Oxygen Consumption

2013
Enhanced aldehyde dehydrogenase activity by regenerating NAD+ in Klebsiella pneumoniae and implications for the glycerol dissimilation pathways.
    Biotechnology letters, 2013, Volume: 35, Issue:10

    Topics: Aldehyde Dehydrogenase; Gene Expression; Glyceraldehyde; Glycerol; Glycerolphosphate Dehydrogenase; Klebsiella pneumoniae; Lactic Acid; Metabolic Engineering; Metabolic Networks and Pathways; Multienzyme Complexes; NAD; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Propane; Recombinant Proteins; Saccharomyces cerevisiae Proteins

2013
Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.
    Anti-cancer drugs, 2013, Volume: 24, Issue:8

    Topics: Adenosine Triphosphate; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Inhibitory Concentration 50; Isocoumarins; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; NAD; Proto-Oncogene Proteins c-myc; Signal Transduction; Sirtuin 1; Time Factors

2013
Label-free high-throughput assays to screen and characterize novel lactate dehydrogenase inhibitors.
    Analytical biochemistry, 2013, Oct-15, Volume: 441, Issue:2

    Topics: Enzyme Assays; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; L-Lactate Dehydrogenase; Lactic Acid; Mass Spectrometry; NAD; Neoplasms; Pyruvic Acid; Spectrometry, Fluorescence

2013
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.
    Nature communications, 2013, Volume: 4

    Topics: Acetates; Cell Hypoxia; Cell Line, Tumor; Cells; Citric Acid; Citric Acid Cycle; Fatty Acids; Glutamine; Humans; Ketoglutaric Acids; Lactic Acid; Models, Biological; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase

2013
Contributions of citrate in redox potential maintenance and ATP production: metabolic pathways and their regulation in Lactobacillus panis PM1.
    Applied microbiology and biotechnology, 2013, Volume: 97, Issue:19

    Topics: Acetates; Adenosine Triphosphate; Citric Acid; DNA, Bacterial; Energy Metabolism; Enzymes; Gene Expression Regulation, Bacterial; Lactic Acid; Lactobacillus; Molecular Sequence Data; NAD; Oxidation-Reduction; Sequence Analysis, DNA; Succinic Acid

2013
Nudix hydrolase controls nucleotides and glycolytic mechanisms in hypoxic Aspergillus nidulans.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:9

    Topics: Adenosine Diphosphate Ribose; Aspergillus nidulans; Ethanol; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Lactic Acid; NAD; Nudix Hydrolases; Oxidation-Reduction; Oxygen; Pyrophosphatases; Up-Regulation

2013
Live-cell imaging of cytosolic NADH-NAD+ redox state using a genetically encoded fluorescent biosensor.
    Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1071

    Topics: Animals; Biosensing Techniques; Calibration; Cell Line, Tumor; Cell Survival; Cytosol; Lactic Acid; Luminescent Proteins; Mice; Molecular Imaging; NAD; Oxidation-Reduction; Protein Engineering; Pyruvic Acid; Single-Cell Analysis

2014
Rapid manifestation of reactive astrogliosis in acute hippocampal brain slices.
    Glia, 2014, Volume: 62, Issue:1

    Topics: Animals; Animals, Newborn; Aquaporin 4; Astrocytes; Calcium; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Glycogen; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Lactic Acid; Male; Mice; NAD; Quaternary Ammonium Compounds

2014
Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes.
    The Journal of biological chemistry, 2014, Jan-24, Volume: 289, Issue:4

    Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glucose; Glycolysis; Humans; Lactic Acid; Male; NAD; Prostatic Neoplasms; Pyruvic Acid

2014
Effect of epidermal growth factor-like peptides on the metabolism of in vitro- matured mouse oocytes and cumulus cells.
    Biology of reproduction, 2014, Volume: 90, Issue:3

    Topics: Animals; Benzimidazoles; Carbocyanines; Cumulus Cells; Epidermal Growth Factor; Female; Flavin-Adenine Dinucleotide; Fluorescent Dyes; Follicle Stimulating Hormone; Glucose; Glycolysis; Hexosamines; Immunohistochemistry; Lactic Acid; Membrane Potential, Mitochondrial; Mice; NAD; Oocytes; Oxidation-Reduction; Peptides; Real-Time Polymerase Chain Reaction; RNA

2014
Purification and characterization of a urea sensitive lactate dehydrogenase from the liver of the African clawed frog, Xenopus laevis.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2014, Volume: 184, Issue:5

    Topics: Animals; Dehydration; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; NAD; Protein Processing, Post-Translational; Pyruvic Acid; Urea; Xenopus laevis

2014
Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Autophagy; bcl-2-Associated X Protein; Carbon Isotopes; Cell Line, Tumor; Furans; Gene Knockdown Techniques; Humans; Isotope Labeling; L-Lactate Dehydrogenase; Lactic Acid; NAD; Neoplasms; Pyridines; Pyrimidines

2014
A novel mode of lactate metabolism in strictly anaerobic bacteria.
    Environmental microbiology, 2015, Volume: 17, Issue:3

    Topics: Acetobacterium; Bacteria, Anaerobic; Catalysis; Electron Transport; Electron-Transferring Flavoproteins; Electrons; Energy Metabolism; Ferredoxins; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxidation-Reduction; Sodium

2015
Beyond Warburg effect--dual metabolic nature of cancer cells.
    Scientific reports, 2014, May-13, Volume: 4

    Topics: Acidosis, Lactic; Animals; Biological Transport; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Glucose; Glycolysis; Heterografts; Humans; Hydrogen-Ion Concentration; Lactic Acid; Mice; NAD; Neoplasms; Oxygen Consumption; Phenotype

2014
Optimal cofactor swapping can increase the theoretical yield for chemical production in Escherichia coli and Saccharomyces cerevisiae.
    Metabolic engineering, 2014, Volume: 24

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Escherichia coli; Escherichia coli Proteins; Lactic Acid; NAD; NADP; Oxidoreductases; Pentanoic Acids; Propylene Glycols; Putrescine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Styrene

2014
Dichloroacetate induces autophagy in colorectal cancer cells and tumours.
    British journal of cancer, 2014, Jul-15, Volume: 111, Issue:2

    Topics: Animals; Apoptosis; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Colorectal Neoplasms; Dichloroacetic Acid; Female; HCT116 Cells; HT29 Cells; Humans; Lactic Acid; Mice; Mice, Nude; Microscopy, Electron; NAD; Random Allocation; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand; TOR Serine-Threonine Kinases

2014
Paper microfluidic-based enzyme catalyzed double microreactor.
    Electrophoresis, 2014, Volume: 35, Issue:16

    Topics: Animals; Bioreactors; Cattle; Dihydrolipoamide Dehydrogenase; Enzymes, Immobilized; Equipment Design; Fluorescence; Fluorescent Dyes; L-Lactate Dehydrogenase; Lactic Acid; Microfluidic Analytical Techniques; NAD; Oxazines; Paper; Potassium Chloride; Pyruvic Acid; Serum Albumin, Bovine; Xanthenes

2014
Utilization of excess NADH in 2,3-butanediol-deficient Klebsiella pneumoniae for 1,3-propanediol production.
    Journal of applied microbiology, 2014, Volume: 117, Issue:3

    Topics: Alcohol Dehydrogenase; Butylene Glycols; Fermentation; Glycerol; Klebsiella pneumoniae; Lactic Acid; Mutation; NAD; Propylene Glycols

2014
NAD(+)-independent aldehyde oxidase catalyzes cofactor balanced 3-hydroxypropionic acid production in Klebsiella pneumoniae.
    Biotechnology letters, 2014, Volume: 36, Issue:11

    Topics: Aldehyde Dehydrogenase; Aldehyde Oxidase; Biomass; Bioreactors; Biotechnology; Klebsiella pneumoniae; Lactic Acid; NAD; Pseudomonas; Recombinant Proteins

2014
Enhanced acetic acid and succinic acid production under microaerobic conditions by Corynebacterium glutamicum harboring Escherichia coli transhydrogenase gene pntAB.
    The Journal of general and applied microbiology, 2014, Volume: 60, Issue:3

    Topics: Acetic Acid; Aerobiosis; Anaerobiosis; Corynebacterium glutamicum; Escherichia coli Proteins; Lactic Acid; Metabolic Engineering; NAD; NADP; NADP Transhydrogenases; Recombinant Proteins; Succinic Acid

2014
Mitochondriome and cholangiocellular carcinoma.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Amino Acid Substitution; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cholangiocarcinoma; DNA Copy Number Variations; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; Molecular Sequence Annotation; Mutation; NAD; Oxidative Phosphorylation; RNA, Ribosomal; RNA, Transfer

2014
Improved bioethanol production in an engineered Kluyveromyces lactis strain shifted from respiratory to fermentative metabolism by deletion of NDI1.
    Microbial biotechnology, 2015, Volume: 8, Issue:2

    Topics: Ethanol; Fermentation; Gene Deletion; Glucose; Kluyveromyces; Lactic Acid; Metabolic Engineering; Mitochondria; NAD; Oxidation-Reduction; Oxidoreductases

2015
Parental environmental exposure leads to glycometabolic disturbances that affect fertilization of eggs in the silkworm Bombyx mori: the parental transcript legacy.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2015, Volume: 185, Issue:1

    Topics: Animals; Bombyx; Citric Acid Cycle; Environmental Exposure; Fertilization; Germ Cells; Glycolysis; Lactic Acid; Light; NAD; Pyruvic Acid; Real-Time Polymerase Chain Reaction

2015
Hydroxycinnamic acids used as external acceptors of electrons: an energetic advantage for strictly heterofermentative lactic acid bacteria.
    Applied and environmental microbiology, 2014, Volume: 80, Issue:24

    Topics: Acetate Kinase; Adenosine Triphosphate; Alcohol Dehydrogenase; Bacterial Proteins; Coumaric Acids; Culture Media; Electron Transport; Energy Metabolism; Fermentation; Lactic Acid; Lactobacillus; NAD; Weissella

2014
Hollow microgel based ultrathin thermoresponsive membranes for separation, synthesis, and catalytic applications.
    ACS applied materials & interfaces, 2014, Oct-22, Volume: 6, Issue:20

    Topics: Catalysis; Coloring Agents; Cross-Linking Reagents; Enzymes, Immobilized; Gels; Gold; L-Lactate Dehydrogenase; Lactic Acid; Membranes, Artificial; Metal Nanoparticles; Microscopy, Electron, Scanning; Muramidase; NAD; Pyruvic Acid; Temperature; Water

2014
3-Hydroxypropionaldehyde-specific aldehyde dehydrogenase from Bacillus subtilis catalyzes 3-hydroxypropionic acid production in Klebsiella pneumoniae.
    Biotechnology letters, 2015, Volume: 37, Issue:3

    Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Bacillus subtilis; Binding Sites; Bioreactors; Biotransformation; Cloning, Molecular; Coenzymes; Gene Expression; Glyceraldehyde; Kinetics; Klebsiella pneumoniae; Lactic Acid; Models, Molecular; Molecular Sequence Data; NAD; Propane; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity

2015
Age-related metabolic fatigue during low glucose conditions in rat hippocampus.
    Neurobiology of aging, 2015, Volume: 36, Issue:2

    Topics: Aging; Animals; CA1 Region, Hippocampal; Glucose; Glycogen; Hypoglycemia; In Vitro Techniques; Lactic Acid; Mitochondria; NAD; Neurons; Oxidation-Reduction; Oxygen Consumption; Rats, Inbred F344

2015
β-Lapachone attenuates mitochondrial dysfunction in MELAS cybrid cells.
    Biochemical and biophysical research communications, 2014, 11-21, Volume: 454, Issue:3

    Topics: DNA, Mitochondrial; Energy Metabolism; Gene Expression Regulation; HeLa Cells; Humans; Lactic Acid; MELAS Syndrome; Membrane Potential, Mitochondrial; Mitochondria; NAD; Naphthoquinones; Reactive Oxygen Species

2014
Development of an enzymatic chromatography strip with nicotinamide adenine dinucleotide-tetrazolium coupling reactions for quantitative l-lactate analysis.
    Analytical biochemistry, 2015, Feb-15, Volume: 471

    Topics: Animals; Chromatography; Clostridium kluyveri; Enzymes, Immobilized; Humans; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Limit of Detection; NAD; Rabbits; Reagent Strips; Tetrazolium Salts

2015
Water-insoluble material from apple pomace makes changes in intracellular NAD⁺/NADH ratio and pyrophosphate content and stimulates fermentative production of hydrogen.
    Journal of bioscience and bioengineering, 2015, Volume: 119, Issue:5

    Topics: Batch Cell Culture Techniques; Bioreactors; Carbohydrate Metabolism; Clostridium; Diphosphates; Fermentation; Hydrogen; Hydrogen-Ion Concentration; Japan; L-Lactate Dehydrogenase; Lactic Acid; Malus; NAD; Oxidation-Reduction; Solubility; Temperature; Water

2015
NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:5

    Topics: Female; Glutamine; Glycolysis; Humans; Lactic Acid; MCF-7 Cells; NAD; Starvation; Tumor Microenvironment

2015
Lactic acid production from biomass-derived sugars via co-fermentation of Lactobacillus brevis and Lactobacillus plantarum.
    Journal of bioscience and bioengineering, 2015, Volume: 119, Issue:6

    Topics: Biomass; Bioreactors; Carbohydrate Metabolism; Catabolite Repression; Cellulose; Coculture Techniques; Ethanol; Fermentation; Glucose; Hydrolysis; Lactic Acid; Lactobacillus plantarum; Levilactobacillus brevis; NAD; Polysaccharides; Xylose; Zea mays

2015
Correlation of NADH fluorescence lifetime and oxidative phosphorylation metabolism in the osteogenic differentiation of human mesenchymal stem cell.
    Journal of biomedical optics, 2015, Volume: 20, Issue:1

    Topics: Adenosine Triphosphate; Cell Differentiation; Cells, Cultured; Humans; Lactic Acid; Mesenchymal Stem Cells; Microscopy, Fluorescence; NAD; Oligomycins; Osteogenesis; Oxidative Phosphorylation; Oxygen Consumption

2015
Multi-timescale modeling of activity-dependent metabolic coupling in the neuron-glia-vasculature ensemble.
    PLoS computational biology, 2015, Volume: 11, Issue:2

    Topics: Animals; Astrocytes; Brain; Cerebrovascular Circulation; Computational Biology; Computer Simulation; Extracellular Space; Glucose; Humans; Lactic Acid; Models, Cardiovascular; Models, Neurological; NAD; Neurons; Oxygen Consumption; Rats; Sodium

2015
Lactate up-regulates the expression of lactate oxidation complex-related genes in left ventricular cardiac tissue of rats.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Antioxidants; Catalase; Energy Metabolism; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Hydrogen Peroxide; In Vitro Techniques; Lactic Acid; Male; Myocardium; NAD; NADPH Oxidases; Oxidation-Reduction; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Up-Regulation; Ventricular Function

2015
Influence of Altered NADH Metabolic Pathway on the Respiratory-deficient Mutant of Rhizopus oryzae and its L-lactate Production.
    Applied biochemistry and biotechnology, 2015, Volume: 176, Issue:7

    Topics: Adenosine Triphosphate; Dose-Response Relationship, Drug; Energy Metabolism; Fermentation; Gluconates; Glycolysis; Intracellular Space; Lactic Acid; Mutagenesis; Mutation; NAD; Oxidation-Reduction; Rhizopus; Ultraviolet Rays

2015
Bio-transformation of Glycerol to 3-Hydroxypropionic Acid Using Resting Cells of Lactobacillus reuteri.
    Current microbiology, 2015, Volume: 71, Issue:4

    Topics: Biotransformation; Catabolite Repression; Feedback, Physiological; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glycerol; Lactic Acid; Limosilactobacillus reuteri; NAD; Propylene Glycols

2015
Regulation of Lactobacillus plantarum contamination on the carbohydrate and energy related metabolisms of Saccharomyces cerevisiae during bioethanol fermentation.
    The international journal of biochemistry & cell biology, 2015, Volume: 68

    Topics: Biofuels; Carbon Cycle; Energy Metabolism; Ethanol; Fermentation; Gene Expression Regulation, Fungal; Glycerol; Industrial Microbiology; Lactic Acid; Lactobacillus plantarum; Metabolic Networks and Pathways; Microbial Interactions; NAD; Saccharomyces cerevisiae

2015
Feeding the fibrillating heart: Dichloroacetate improves cardiac contractile dysfunction following VF.
    American journal of physiology. Heart and circulatory physiology, 2015, Volume: 309, Issue:9

    Topics: Animals; Dichloroacetic Acid; Heart; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; NAD; Phosphorylation; Pressure; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left; Ventricular Fibrillation; Ventricular Function, Left

2015
Regulation of EPS production in Lactobacillus casei LC2W through metabolic engineering.
    Letters in applied microbiology, 2015, Volume: 61, Issue:6

    Topics: Fermentation; Lactic Acid; Lacticaseibacillus casei; Metabolic Engineering; Molecular Sequence Data; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Peptidoglycan Glycosyltransferase; Phosphofructokinases; Polysaccharides, Bacterial; Probiotics; UTP-Hexose-1-Phosphate Uridylyltransferase

2015
Half-sandwich rhodium(III) transfer hydrogenation catalysts: Reduction of NAD(+) and pyruvate, and antiproliferative activity.
    Journal of inorganic biochemistry, 2015, Volume: 153

    Topics: Catalysis; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Formates; Humans; Hydrogenation; Lactic Acid; NAD; Oxidation-Reduction; Pyruvates; Rhodium

2015
Gold Nanoparticles Deposited Polyaniline-TiO2 Nanotube for Surface Plasmon Resonance Enhanced Photoelectrochemical Biosensing.
    ACS applied materials & interfaces, 2016, Jan-13, Volume: 8, Issue:1

    Topics: Aniline Compounds; Biosensing Techniques; Carbon; Electrochemistry; Electrodes; Glass; Gold; Lactic Acid; Metal Nanoparticles; NAD; Nanotubes, Carbon; Photochemistry; Spectrophotometry, Ultraviolet; Surface Plasmon Resonance; Tin Compounds; Titanium

2016
Functional surface engineering of quantum dot hydrogels for selective fluorescence imaging of extracellular lactate release.
    Biosensors & bioelectronics, 2016, Jun-15, Volume: 80

    Topics: Biosensing Techniques; Cadmium Compounds; Fluorescence; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; HeLa Cells; Humans; Hydrogels; Lactic Acid; NAD; Optical Imaging; Oxazines; Quantum Dots; Tellurium

2016
Cytosolic NADH-NAD(+) Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging.
    Antioxidants & redox signaling, 2016, 10-01, Volume: 25, Issue:10

    Topics: Animals; Astrocytes; Biosensing Techniques; Cytosol; Glucose; Glycolysis; Hippocampus; Lactic Acid; Mice; NAD; Neurons; Oxidation-Reduction

2016
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.
    Nature immunology, 2016, Volume: 17, Issue:4

    Topics: Adenosine Triphosphate; Adult; Animals; Antifungal Agents; Aspergillosis; Candidiasis, Invasive; Cytokines; Endotoxemia; Energy Metabolism; Escherichia coli Infections; Female; Glycolysis; Humans; Immune Tolerance; Immunity, Innate; Immunoblotting; Interferon-gamma; Lactic Acid; Leukocytes; Lipopolysaccharides; Macrophages; Male; Mice; Middle Aged; Monocytes; NAD; Oxidative Phosphorylation; Oxygen Consumption; Prospective Studies; Sepsis; Transcriptome; Young Adult

2016
Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics.
    Human & experimental toxicology, 2017, Volume: 36, Issue:6

    Topics: Adenosine Triphosphate; Antitubercular Agents; Drug Interactions; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Hep G2 Cells; Humans; Isoniazid; Lactic Acid; Membrane Potential, Mitochondrial; NAD; Pyrazinamide; Rifampin

2017
Bioenergetic Impairment in Animal and Cellular Models of Alzheimer's Disease: PARP-1 Inhibition Rescues Metabolic Dysfunctions.
    Journal of Alzheimer's disease : JAD, 2016, 08-10, Volume: 54, Issue:1

    Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line, Tumor; CHO Cells; Citrate (si)-Synthase; Cricetulus; Disease Models, Animal; Electron Transport Complex IV; Entorhinal Cortex; Enzyme Inhibitors; Hippocampus; Lactic Acid; Membrane Potential, Mitochondrial; Mice, Transgenic; Mitochondria; NAD; Neuroprotective Agents; Peptide Fragments; Poly (ADP-Ribose) Polymerase-1

2016
A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect.
    Biophysical journal, 2016, Sep-06, Volume: 111, Issue:5

    Topics: Adenosine Triphosphate; Algorithms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Glucose; Glycolysis; Humans; Lactic Acid; Mitochondria; Models, Molecular; NAD; Oxidation-Reduction; Oxygen

2016
GSF2 deletion increases lactic acid production by alleviating glucose repression in Saccharomyces cerevisiae.
    Scientific reports, 2016, 10-06, Volume: 6

    Topics: Catabolite Repression; Evolution, Molecular; Gene Deletion; Genome, Fungal; Glucose; Hexokinase; Lactic Acid; Membrane Proteins; Mutation; NAD; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2016
Kvβ1.1 (AKR6A8) senses pyridine nucleotide changes in the mouse heart and modulates cardiac electrical activity.
    American journal of physiology. Heart and circulatory physiology, 2017, Mar-01, Volume: 312, Issue:3

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Chlorocebus aethiops; COS Cells; Electrophysiological Phenomena; Heart; Isoproterenol; Kv1.1 Potassium Channel; Lactic Acid; Male; Mice; Mice, Knockout; Myocardium; NAD; Nucleotides; Patch-Clamp Techniques; Pyridines; Rats; Shal Potassium Channels

2017
Spectrophotometric assay for sensitive detection of glycerol dehydratase activity using aldehyde dehydrogenase.
    Journal of bioscience and bioengineering, 2017, Volume: 123, Issue:4

    Topics: Aldehyde Dehydrogenase; Fermentation; Glyceraldehyde; Glycerol; Hydro-Lyases; Kinetics; Lactic Acid; Limit of Detection; NAD; Propane; Spectrophotometry

2017
New approach to biosensing of co-enzyme nicotinamide adenine dinucleotide (NADH) by incorporation of neutral red in aluminum doped nanostructured ZnO thin films.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:6

    Topics: Adsorption; Aluminum Compounds; Biosensing Techniques; Citric Acid; Electric Conductivity; Electrodes; Equipment Design; Gallium; Humans; L-Lactate Dehydrogenase; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; NAD; Nanotechnology; Nanotubes; Neutral Red; Particle Size; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Surface Properties; Time Factors; X-Ray Diffraction; Zinc Oxide

2017
Structural insights into the production of 3-hydroxypropionic acid by aldehyde dehydrogenase from Azospirillum brasilense.
    Scientific reports, 2017, 04-10, Volume: 7

    Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Azospirillum brasilense; Binding Sites; Biocatalysis; Lactic Acid; Molecular Docking Simulation; NAD; NADP; Static Electricity; Substrate Specificity

2017
The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
    Cell death & disease, 2017, 06-01, Volume: 8, Issue:6

    Topics: Adamantane; Animals; Antineoplastic Agents; Cell Proliferation; Colorectal Neoplasms; Cyclic AMP; Female; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; HCT116 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Mice; Mice, Nude; NAD; Neovascularization, Pathologic; Piperazines; Proto-Oncogene Proteins p21(ras); PTEN Phosphohydrolase; Signal Transduction; TOR Serine-Threonine Kinases; Von Hippel-Lindau Tumor Suppressor Protein; Xenograft Model Antitumor Assays

2017
Upregulation of mitochondrial NAD
    Experimental & molecular medicine, 2017, 06-09, Volume: 49, Issue:6

    Topics: Aging; Animals; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Colony-Forming Units Assay; Glioblastoma; Humans; Lactic Acid; Lewis X Antigen; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; NAD; NADP Transhydrogenases; Neoplastic Stem Cells; Oxygen Consumption; RNA, Small Interfering; Sirtuin 3; Xenograft Model Antitumor Assays

2017
Fabrication of Flexible Arrayed Lactate Biosensor Based on Immobilizing LDH-NAD⁺ on NiO Film Modified by GO and MBs.
    Sensors (Basel, Switzerland), 2017, Jul-12, Volume: 17, Issue:7

    Topics: Biosensing Techniques; Graphite; L-Lactate Dehydrogenase; Lactic Acid; NAD

2017
A Bacterial Multidomain NAD-Independent d-Lactate Dehydrogenase Utilizes Flavin Adenine Dinucleotide and Fe-S Clusters as Cofactors and Quinone as an Electron Acceptor for d-Lactate Oxidization.
    Journal of bacteriology, 2017, 11-15, Volume: 199, Issue:22

    Topics: Bacterial Proteins; Coenzymes; Cytochromes c; Electrons; Flavin-Adenine Dinucleotide; Iron-Sulfur Proteins; Lactate Dehydrogenases; Lactic Acid; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Pseudomonas putida; Quinones; Ubiquinone

2017
Nicotine Adenine Dinucleotides: The Redox Currency of the Cell.
    Antioxidants & redox signaling, 2018, Jan-20, Volume: 28, Issue:3

    Topics: Humans; Lactic Acid; NAD; Oxidation-Reduction; Pyruvic Acid

2018
Lactate is oxidized outside of the mitochondrial matrix in rodent brain.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2018, Volume: 43, Issue:5

    Topics: Animals; Brain; Glutamates; L-Lactate Dehydrogenase; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; Monocarboxylic Acid Transporters; Muscle Fibers, Skeletal; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Rats; Rats, Wistar

2018
Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD
    Scientific reports, 2017, 12-07, Volume: 7, Issue:1

    Topics: Aldehyde Oxidoreductases; Azospirillum brasilense; Bacterial Proteins; Glyceraldehyde; Glycerol; Lactic Acid; NAD; Propane; Protein Conformation; Protein Engineering; Substrate Specificity

2017
Rational design of engineered microbial cell surface multi-enzyme co-display system for sustainable NADH regeneration from low-cost biomass.
    Journal of industrial microbiology & biotechnology, 2018, Volume: 45, Issue:2

    Topics: Biomass; Cell Cycle Proteins; Cell Membrane; Chromosomal Proteins, Non-Histone; Cohesins; Escherichia coli; Glucan 1,4-alpha-Glucosidase; Glucose 1-Dehydrogenase; Lactic Acid; NAD; Oxidation-Reduction

2018
Using metabolic charge production in the tricarboxylic acid cycle (Q
    Bioelectrochemistry (Amsterdam, Netherlands), 2018, Volume: 124

    Topics: Anthraquinones; Biomass; Citric Acid Cycle; Electron Transport; Ferricyanides; Hydrogen-Ion Concentration; Lactic Acid; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Riboflavin; Shewanella; Sulfonic Acids

2018
Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Adenosine Triphosphate; Cytoplasm; Cytosol; Energy Metabolism; Extracellular Space; Glycolysis; Lactic Acid; Metabolic Flux Analysis; Models, Biological; NAD

2018
Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells.
    Cell reports, 2018, 12-11, Volume: 25, Issue:11

    Topics: Acids; Animals; Cell Line, Tumor; Energy Metabolism; Humans; Intracellular Space; Lactic Acid; Male; Metformin; Mice, Inbred C57BL; Monocarboxylic Acid Transporters; Muscle Proteins; NAD; Neoplasms; Reserpine; Symporters; Synthetic Lethal Mutations

2018
Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism.
    The Journal of biological chemistry, 2019, 02-22, Volume: 294, Issue:8

    Topics: Animals; Aspartic Acid; Cells, Cultured; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glycolysis; Hepatocytes; Hypoglycemic Agents; Lactic Acid; Malates; Male; Metformin; Mice; Mice, Inbred C57BL; Mitochondria, Liver; NAD; Oxidation-Reduction; Phosphofructokinase-1; Rats; Rats, Wistar

2019
A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures.
    Magnetic resonance in medicine, 2019, Volume: 81, Issue:5

    Topics: Animals; Bioreactors; Cell Line, Tumor; Cell Survival; Collagen; Contrast Media; Diffusion; Disease Progression; Equipment Design; Female; Gels; Glucose; Lactic Acid; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; NAD; Optical Imaging; Printing, Three-Dimensional; Pyruvic Acid; Temperature

2019
Comparison of Lactate Dehydrogenase Activity in Hive and Forager Honeybees May Indicate Delayed Onset Muscle Soreness - Preliminary Studies.
    Biochemistry. Biokhimiia, 2019, Volume: 84, Issue:4

    Topics: Animals; Bees; Fat Body; Hemolymph; L-Lactate Dehydrogenase; Lactic Acid; Muscle, Skeletal; Myalgia; NAD

2019
Effect of infectious bursal disease virus infection on energy metabolism in embryonic chicken livers.
    British poultry science, 2019, Volume: 60, Issue:6

    Topics: Adenosine Triphosphate; Animals; Chick Embryo; Chorioallantoic Membrane; Cytosol; Electron Transport Complex I; Energy Metabolism; Glycolysis; Infectious bursal disease virus; L-Lactate Dehydrogenase; Lactic Acid; Liver; Luminescent Measurements; Mitochondria; NAD; Phosphopyruvate Hydratase; Proteins; Pyruvic Acid; Random Allocation; RNA, Viral; Specific Pathogen-Free Organisms; Virulence; Virus Replication

2019
Lactate dehydrogenase and glycerol-3-phosphate dehydrogenase cooperatively regulate growth and carbohydrate metabolism during
    Development (Cambridge, England), 2019, 09-12, Volume: 146, Issue:17

    Topics: Adenosine Triphosphate; Animals; Animals, Genetically Modified; Drosophila melanogaster; Female; Glycerolphosphate Dehydrogenase; Glycolysis; Homeostasis; L-Lactate Dehydrogenase; Lactic Acid; Larva; Male; Mutation; NAD; Oxidation-Reduction; Sugars

2019
A Semi-High-Throughput Adaptation of the NADH-Coupled ATPase Assay for Screening Small Molecule Inhibitors.
    Journal of visualized experiments : JoVE, 2019, 08-17, Issue:150

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Enzyme Inhibitors; High-Throughput Screening Assays; Hydrolysis; Lactic Acid; Myosin Type II; NAD; Oxidation-Reduction; Pyruvic Acid

2019
Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria.
    Journal of cellular physiology, 2020, Volume: 235, Issue:3

    Topics: Aspartic Acid; Colonic Neoplasms; HCT116 Cells; Homeostasis; Humans; Lactic Acid; Malates; Mitochondria; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Warburg Effect, Oncologic

2020
NADH dehydrogenases Nuo and Nqr1 contribute to extracellular electron transfer by Shewanella oneidensis MR-1 in bioelectrochemical systems.
    Scientific reports, 2019, 10-18, Volume: 9, Issue:1

    Topics: Acetates; Biosensing Techniques; Electrodes; Electron Transport; Electrons; Ferric Compounds; Gene Expression Regulation, Bacterial; Genome, Bacterial; Iron; Lactic Acid; NAD; NADH Dehydrogenase; Oxygen; Pyruvate Dehydrogenase Complex; Shewanella

2019
Screen-Printed Carbon Electrodes Modified with Graphene Oxide for the Design of a Reagent-Free NAD
    Analytical chemistry, 2019, 12-03, Volume: 91, Issue:23

    Topics: Biosensing Techniques; Carbon; Electrochemical Techniques; Electrodes; Enzymes, Immobilized; Ethanol; Ferricyanides; Formates; Graphite; Hydrogen-Ion Concentration; Lactic Acid; NAD; Oxidoreductases; Silver

2019
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD
    Nature biotechnology, 2020, Volume: 38, Issue:3

    Topics: Bacteria; Bacterial Proteins; Catalase; HeLa Cells; Humans; K562 Cells; Lactic Acid; Mixed Function Oxygenases; NAD; Protein Engineering; Pyruvic Acid; Recombinant Fusion Proteins

2020
Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer.
    FEBS letters, 2020, Volume: 594, Issue:9

    Topics: Acrylamides; Cell Line, Tumor; Cytokines; Female; Glycolysis; Humans; Lactic Acid; NAD; Niacin; Nicotinamide Phosphoribosyltransferase; Ovarian Neoplasms; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors

2020
Tunable 3D nanofibrous and bio-functionalised PEDOT network explored as a conducting polymer-based biosensor.
    Biosensors & bioelectronics, 2020, Jul-01, Volume: 159

    Topics: Biosensing Techniques; Bridged Bicyclo Compounds, Heterocyclic; Lactic Acid; NAD; Nanofibers; Nanostructures; Polymerization; Polymers

2020
Sustained Immunoparalysis in Endotoxin-Tolerized Monocytic Cells.
    Mediators of inflammation, 2020, Volume: 2020

    Topics: Adenosine Triphosphate; Cell Line; Cells, Cultured; Endotoxins; Enzyme-Linked Immunosorbent Assay; Healthy Volunteers; Humans; Lactic Acid; Leukocytes, Mononuclear; Lipopolysaccharides; NAD; Real-Time Polymerase Chain Reaction; THP-1 Cells

2020
Suppression of lactate production by aerobic fed-batch cultures of Lactococcus lactis.
    Journal of bioscience and bioengineering, 2020, Volume: 130, Issue:4

    Topics: Aerobiosis; Batch Cell Culture Techniques; Glucose; Glycolysis; L-Lactate Dehydrogenase; Lactic Acid; Lactococcus lactis; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases

2020
Intensifying niacin-based biosynthesis of NAD
    Biotechnology letters, 2021, Volume: 43, Issue:1

    Topics: Aldehyde Dehydrogenase; Bacterial Proteins; Bioreactors; Glycerol; Klebsiella pneumoniae; Lactic Acid; Metabolic Engineering; NAD; Niacin; Recombinant Proteins

2021
Lactate Limits T Cell Proliferation via the NAD(H) Redox State.
    Cell reports, 2020, 12-15, Volume: 33, Issue:11

    Topics: Cell Proliferation; Humans; Lactic Acid; NAD; Oxidation-Reduction

2020
Identifying metastatic ability of prostate cancer cell lines using native fluorescence spectroscopy and machine learning methods.
    Scientific reports, 2021, 01-26, Volume: 11, Issue:1

    Topics: Cell Line, Tumor; Humans; Lactic Acid; Machine Learning; Male; NAD; Neoplasm Metastasis; Principal Component Analysis; Prostatic Neoplasms; Reproducibility of Results; ROC Curve; Spectrometry, Fluorescence; Support Vector Machine; Tryptophan

2021
Could mitochondria help athletes to make gains?
    Nature, 2021, Volume: 592, Issue:7852

    Topics: Acclimatization; Adenosine Triphosphate; Altitude; Animals; Athletes; Glucose; Heat-Shock Proteins; Hot Temperature; Humans; Lactic Acid; Male; Mice; Mitochondria; Mitochondrial Dynamics; NAD; Oxygen; Phosphocreatine; Physical Endurance; Rats

2021
In vitro angiogenesis inhibition with selective compounds targeting the key glycolytic enzyme PFKFB3.
    Pharmacological research, 2021, Volume: 168

    Topics: Angiogenesis Inhibitors; Cells, Cultured; Humans; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; NAD; Neovascularization, Pathologic; Phosphofructokinase-2; Symporters

2021
Fully automatic d-lactate assay using a modified commercially available method.
    Scandinavian journal of clinical and laboratory investigation, 2021, Volume: 81, Issue:4

    Topics: Automation, Laboratory; Blood Chemical Analysis; Emulsions; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Limit of Detection; Mesenteric Ischemia; NAD; Phospholipids; Reagent Kits, Diagnostic; Reproducibility of Results; Soybean Oil; Spectrophotometry

2021
Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 06-22, Volume: 118, Issue:25

    Topics: B-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Epstein-Barr Virus Infections; Glucose; Glutathione; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Lactic Acid; Lymphoma; Metformin; Monocarboxylic Acid Transporters; NAD; Oxygen Consumption; Phenformin; Reactive Oxygen Species; Up-Regulation

2021
Lactate metabolism in strictly anaerobic microorganisms with a soluble NAD
    Environmental microbiology, 2021, Volume: 23, Issue:8

    Topics: Anaerobiosis; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxidation-Reduction

2021
Lactate and Pyruvate Activate Autophagy and Mitophagy that Protect Cells in Toxic Model of Parkinson's Disease.
    Molecular neurobiology, 2022, Volume: 59, Issue:1

    Topics: Animals; Astrocytes; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Mitophagy; NAD; Neurons; Parkinson Disease; Pyruvic Acid; Rats

2022
PI3K Pathway Inhibition with NVP-BEZ235 Hinders Glycolytic Metabolism in Glioblastoma Multiforme Cells.
    Cells, 2021, 11-07, Volume: 10, Issue:11

    Topics: Brain Neoplasms; Cell Line, Tumor; Forkhead Box Protein O1; Gene Expression Regulation, Neoplastic; Gene Ontology; Glioblastoma; Glucose; Glutamic Acid; Glycolysis; Humans; Imidazoles; Kaplan-Meier Estimate; Lactic Acid; NAD; Phosphatidylinositol 3-Kinases; Prognosis; Protein Kinase Inhibitors; Quinolines; Signal Transduction

2021
Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions.
    International journal of molecular sciences, 2022, Jan-17, Volume: 23, Issue:2

    Topics: Cell Line, Tumor; Cell Proliferation; Culture Media; Glucose; Glutamine; HeLa Cells; Humans; Lactic Acid; Metabolomics; Metformin; NAD; Oxygen; Pyruvic Acid; Tumor Hypoxia

2022
Quantitative analysis of the interaction of ethanol metabolism with gluconeogenesis and fatty acid oxidation in the perfused liver of fasted rats.
    Archives of biochemistry and biophysics, 2022, 03-30, Volume: 718

    Topics: Animals; Ethanol; Fatty Acids; Gluconeogenesis; Lactic Acid; Lipid Metabolism; Liver; NAD; Oxidation-Reduction; Pyruvic Acid; Rats

2022
NADH-independent enzymatic assay to quantify extracellular and intracellular L-lactate levels.
    STAR protocols, 2022, 06-17, Volume: 3, Issue:2

    Topics: Energy Metabolism; Enzyme Assays; Lactic Acid; Monocarboxylic Acid Transporters; NAD

2022
Canine urinary lactate and cortisol metabolites in hypercortisolism, nonadrenal disease, congestive heart failure, and health.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2022, Volume: 34, Issue:4

    Topics: Animals; Creatinine; Cushing Syndrome; Dog Diseases; Dogs; Heart Failure; Hydrocortisone; Lactic Acid; NAD

2022
Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 08-15, Volume: 28, Issue:16

    Topics: Animals; Deuterium; Glioblastoma; Lactic Acid; Mice; NAD; Pyruvic Acid; Telomerase

2022
Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells.
    Molecular cell, 2022, 09-01, Volume: 82, Issue:17

    Topics: Aspartic Acid; Glucose; Glycolysis; Lactic Acid; Malates; NAD

2022
Astrocyte-derived lactate/NADH alters methamphetamine-induced memory consolidation and retrieval by regulating neuronal synaptic plasticity in the dorsal hippocampus.
    Brain structure & function, 2022, Volume: 227, Issue:8

    Topics: Animals; Astrocytes; Basic Helix-Loop-Helix Transcription Factors; Hippocampus; Lactic Acid; Memory Consolidation; Methamphetamine; Mice; Mice, Inbred C57BL; NAD; Neuronal Plasticity; Oligodeoxyribonucleotides

2022
An Axis between the Long Non-Coding RNA
    International journal of molecular sciences, 2022, Sep-14, Volume: 23, Issue:18

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Flavin-Adenine Dinucleotide; Genes, Homeobox; Glyceraldehyde-3-Phosphate Dehydrogenases; Homeodomain Proteins; Humans; Lactic Acid; Mice; MicroRNAs; Mouth Neoplasms; NAD; NAD(P)H Dehydrogenase (Quinone); Quinone Reductases; Quinones; RNA, Antisense; RNA, Long Noncoding; Squamous Cell Carcinoma of Head and Neck

2022
Swim Training Affects on Muscle Lactate Metabolism, Nicotinamide Adenine Dinucleotides Concentration, and the Activity of NADH Shuttle Enzymes in a Mouse Model of Amyotrophic Lateral Sclerosis.
    International journal of molecular sciences, 2022, Sep-29, Volume: 23, Issue:19

    Topics: Adenine; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Lactic Acid; Malate Dehydrogenase; Mice; Monocarboxylic Acid Transporters; Muscle, Skeletal; NAD; Niacinamide

2022
A functionally uncharacterized type-2 malate/L-lactate dehydrogenase family protein from Thermus thermophilus HB8 catalyzes stereospecific reduction of 2-keto-3-deoxy-D-gluconate.
    Extremophiles : life under extreme conditions, 2022, Nov-23, Volume: 26, Issue:3

    Topics: L-Lactate Dehydrogenase; Lactic Acid; Malates; NAD; Phylogeny; Thermus thermophilus

2022
Further evidence in favour of a carbanion mechanism for glycolate oxidase.
    FEBS open bio, 2023, Volume: 13, Issue:5

    Topics: Flavins; Humans; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; NAD

2023
Effects of lactate on metabolism and differentiation of CD4
    Molecular immunology, 2023, Volume: 154

    Topics: Cell Differentiation; Cytokines; Forkhead Transcription Factors; Lactic Acid; NAD; T-Lymphocytes, Regulatory; Transforming Growth Factor beta

2023
Electrochemiluminescence (ECL) biosensor based on tris(2,2'-bipyridyl)ruthenium(II) with glucose and lactate dehydrogenases encapsulated within alginate hydrogels.
    Bioelectrochemistry (Amsterdam, Netherlands), 2023, Volume: 150

    Topics: 2,2'-Dipyridyl; Biosensing Techniques; Glucose; Hydrogels; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Luminescent Measurements; NAD; Reproducibility of Results; Ruthenium

2023
NAD
    Biotechnology journal, 2023, Volume: 18, Issue:4

    Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Dietary Supplements; Glucose; Lactic Acid; NAD

2023
Promotion of NAD
    Free radical biology & medicine, 2023, 11-01, Volume: 208

    Topics: Bone Marrow; Cellular Senescence; Endothelial Progenitor Cells; Humans; Hypoxia; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; NAD

2023
A polymer dot-based NADH-sensitive electrochemiluminescence biosensor for analysis of metabolites in serum.
    Talanta, 2024, Jan-15, Volume: 267

    Topics: Biosensing Techniques; Electrochemical Techniques; Glucose; Humans; Lactic Acid; Limit of Detection; Luminescent Measurements; NAD; Polymers; Pyruvates; Quantum Dots

2024
Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes.
    American journal of physiology. Cell physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Humans; Lactate Dehydrogenases; Lactic Acid; Metformin; Muscle Fibers, Skeletal; NAD; Oxidation-Reduction; Oxidoreductases; Pyruvates

2023
Nicotinamide restores tissue NAD+ and improves survival in rodent models of cardiac arrest.
    PloS one, 2023, Volume: 18, Issue:9

    Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Heart Arrest; Lactic Acid; Mice; Myocytes, Cardiac; NAD; Niacinamide; Rats; Rodentia

2023
Hyperpolarized [1-
    Yonsei medical journal, 2023, Volume: 64, Issue:10

    Topics: Agmatine; Animals; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lactic Acid; Mice; Mice, Inbred ICR; NAD; Pyruvic Acid

2023
Multispectral Imaging of Metabolic Fluorophores: Comparing In Vivo and Fresh Ex Vivo Tissue.
    Critical reviews in eukaryotic gene expression, 2024, Volume: 34, Issue:1

    Topics: Animals; Breast Neoplasms; Female; Flavin-Adenine Dinucleotide; Humans; Lactic Acid; Mice; NAD

2024