Page last updated: 2024-09-05

l 767679 and l 734217

l 767679 has been researched along with l 734217 in 4 studies

Compound Research Comparison

Studies
(l 767679)
Trials
(l 767679)
Recent Studies (post-2010)
(l 767679)
Studies
(l 734217)
Trials
(l 734217)
Recent Studies (post-2010) (l 734217)
700800

Protein Interaction Comparison

ProteinTaxonomyl 767679 (IC50)l 734217 (IC50)
Integrin beta-3Homo sapiens (human)0.0275
Integrin alpha-IIbHomo sapiens (human)0.0275

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brashear, KM; Breslin, MJ; Cook, JJ; Glass, JD; Gould, RJ; Halczenko, W; Hartman, GD; Holahan, MA; Hutchinson, JH; Lynch, RJ; Sitko, GR; Stranieri, MT1
Askew, BC; Bednar, B; Bednar, RA; Brashear, K; Breslin, MJ; Duggan, ME; Egbertson, MS; Fisher, TE; Gould, RJ; Halczenko, W; Hartman, GD; Hutchinson, JH; Ihle, N; Prugh, JD; Wai, JS1
Gretler, DD; Scarborough, RM1
Bednar, B; Bednar, RA; Cook, JJ; Cunningham, ME; Gould, RJ; Hartman, GD; Holahan, MA; Jumes, PA1

Reviews

1 review(s) available for l 767679 and l 734217

ArticleYear
Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents.
    Journal of medicinal chemistry, 2000, Sep-21, Volume: 43, Issue:19

    Topics: Administration, Oral; Animals; Antibodies, Monoclonal; Clinical Trials as Topic; Drug Design; Fibrinolytic Agents; Humans; Injections; Integrins; Molecular Mimicry; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Snake Venoms

2000

Other Studies

3 other study(ies) available for l 767679 and l 734217

ArticleYear
Non-peptide glycoprotein IIb/IIIa antagonists. 11. Design and in vivo evaluation of 3,4-dihydro-1 (1H)-isoquinolinone-based antagonists and ethyl ester prodrugs.
    Journal of medicinal chemistry, 1996, Nov-08, Volume: 39, Issue:23

    Topics: Animals; Dogs; Drug Design; Evaluation Studies as Topic; Female; Humans; Isoquinolines; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship

1996
Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors.
    Bioorganic & medicinal chemistry letters, 2000, Sep-04, Volume: 10, Issue:17

    Topics: Amides; Humans; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship

2000
Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa.
    Blood, 1999, Jul-15, Volume: 94, Issue:2

    Topics: Animals; Autoantibodies; Autoimmune Diseases; Azepines; beta-Alanine; Blood Platelets; Disease Susceptibility; Dogs; Epitopes; Female; Fibrinolytic Agents; Humans; Immunoglobulin G; Macaca mulatta; Macromolecular Substances; Male; Molecular Structure; Oligopeptides; Pan troglodytes; Piperazines; Piperidines; Platelet Glycoprotein GPIIb-IIIa Complex; Primates; Protein Binding; Sulfonamides; Thrombocytopenia

1999