l 368899 has been researched along with oxytocin in 35 studies
| Studies (l 368899) | Trials (l 368899) | Recent Studies (post-2010) (l 368899) | Studies (oxytocin) | Trials (oxytocin) | Recent Studies (post-2010) (oxytocin) |
|---|---|---|---|---|---|
| 6 | 0 | 4 | 21,611 | 1,831 | 5,773 |
| 46 | 0 | 30 | 21,611 | 1,831 | 5,773 |
| Protein | Taxonomy | l 368899 (IC50) | oxytocin (IC50) |
|---|---|---|---|
| Oxytocin receptor | Homo sapiens (human) | 0.0027 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (8.57) | 18.2507 |
| 2000's | 5 (14.29) | 29.6817 |
| 2010's | 25 (71.43) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Harrell, CM; Jasper, JR; O'Brien, JA; Pettibone, DJ | 1 |
| Anderson, PS; Ball, RG; Bock, MG; Carroll, L; Chiu, SH; Clineschmidt, BV; Culberson, JC; Erb, JM; Evans, BE; Williams, PD | 1 |
| Bock, MG; Evans, BE; Guidotti, M; Harrell, CM; Jasper, JR; Lis, EV; O'Brien, JA; Pettibone, DJ; Reiss, DR; Woyden, CJ | 1 |
| Bowen, RC; Cui, SS; Gu, GB; Hannesson, DK; Yu, PH; Zhang, X | 1 |
| Hunter, M; Lamming, GE; Mann, GE; Pettibone, DJ; Scholey, D | 1 |
| Honda, K; Ikeda, K; Onaka, T; Yamashita, T | 1 |
| Anderson, KD; Bachevalier, J; Boccia, ML; Goursaud, AP; Pedersen, CA | 1 |
| Hlinak, Z; Hynie, S; Klenerova, V; Krejci, I; Sida, P | 1 |
| Agmo, A; Birnie, AK; French, JA; Smith, AS | 1 |
| Cassano, T; Cianci, S; Cuomo, V; Dipasquale, P; Fu, J; Gaetani, S; Giannini, E; Laconca, L; Mairesse, J; Piomelli, D; Righetti, L; Romano, A; Scaccianoce, S | 1 |
| Fredriksson, R; Klockars, A; Levine, AS; Olszewska, AM; Olszewski, PK; Schiöth, HB | 1 |
| Kay, K; Mullis, K; Williams, DL | 1 |
| Brooks, LL; Herisson, F; Levine, AS; Olszewski, PK; Waas, JR | 1 |
| Douglas, NR; Holmes, MM; Mooney, SJ | 1 |
| Brooks, LL; Herisson, FM; Levine, AS; Olszewski, PK; Waas, JR | 1 |
| Cavanaugh, J; French, JA; Mustoe, AC; Taylor, JH | 1 |
| Althaus, M; Calcagnoli, F; de Boer, SF; Koolhaas, JM; Meyer, N; Stubbendorff, C | 1 |
| Allen, K; Levine, AS; Olszewski, PK | 1 |
| Cox, CD; Gall, CM; Geschwind, DH; Karsten, CA; Lee, D; Peñagarikano, O; Piomelli, D; Wei, D | 1 |
| Choi, SY; Chung, C; Han, JS; Kim, JJ; Lee, SY; Park, SH | 1 |
| Fredriksson, R; Herisson, FM; Levine, AS; Olszewski, PK; Schiöth, HB; Waas, JR | 1 |
| Bonan, CD; Gaspary, KV; Siebel, AM; Zimmermann, FF | 1 |
| Boulet, NP; Cloutier, CJ; Kavaliers, M; Ossenkopp, KP | 1 |
| Cavanaugh, J; French, JA; Taylor, JH | 1 |
| Ikeda, K; Konoike, N; Kotani, M; Matsumoto, K; Nakako, T; Nakamura, K; Ogi, Y; Shimono, K; Yoneyama, T | 1 |
| Arámburo, C; Carranza, M; Condés-Lara, M; González-Hernández, A; Manzano-García, A; Martínez-Lorenzana, G; Tello-García, IA | 1 |
| Bales, KL; Busnelli, M; Chini, B; Duque-Wilckens, N; Hao, R; Laredo, SA; Minie, VA; Perkeybile, AM; Pham, M; Steinman, MQ; Tan, PB; Trainor, BC; Yokoyama, S | 1 |
| Condés-Lara, M; García-Boll, E; González-Hernández, A; Martínez-Lorenzana, G | 1 |
| Klockars, A; Klockars, OA; Levine, AS; Olszewski, PK | 1 |
| Kumei, S; Nozu, T; Ohhira, M; Okumura, T | 1 |
| Cacioppo, S; Dagner, A; Grippo, AJ; McNeal, N; Scotti, ML; Watanasriyakul, WT | 1 |
| Bredewold, R; Eltahir, AM; Hodges, TE; McCormick, CM; Patel, S; Veenema, AH | 1 |
| Chang, CP; Chen, TH; Lin, CH; Tsai, CC; Yang, HH | 1 |
| Hovey, D; Kettunen, P; Lagman, D; Landin, J; Larhammar, D; Westberg, L; Xu, B; Zettergren, A | 1 |
| Fu, M; Huang, CL; Li, CJ; Li, YL; Lin, J; Liu, F; Shen, JF; Zhang, YY; Zhou, C | 1 |
1 review(s) available for l 368899 and oxytocin
| Article | Year |
|---|---|
Progress in the development of oxytocin antagonists for use in preterm labor.
Topics: Animals; Benzoxazines; Camphanes; Dogs; Female; Hormone Antagonists; Humans; In Vitro Techniques; Macaca mulatta; Molecular Structure; Obstetric Labor, Premature; Oxazines; Oxytocin; Pan troglodytes; Piperazines; Piperidines; Pregnancy; Rats; Tocolytic Agents; Uterine Contraction | 1995 |
34 other study(ies) available for l 368899 and oxytocin
| Article | Year |
|---|---|
Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells.
Topics: Arginine Vasopressin; Cell Line; Drug Tolerance; Embryo, Mammalian; Female; Gene Expression; Guanine Nucleotides; Humans; Hydrolysis; Kidney; Myometrium; Oxytocin; Phosphatidylinositols; Receptors, Oxytocin; Recombinant Proteins; Transfection; Tritium | 1995 |
1-((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo [2.2.1]-heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperaz ine (L-368,899): an orally bioavailable, non-peptide oxytocin antagonist with potential utility for managing preterm l
Topics: Animals; Biological Availability; Camphanes; Crystallography, X-Ray; Dogs; Female; Humans; Macaca mulatta; Models, Molecular; Molecular Structure; Obstetric Labor, Premature; Oxytocin; Piperazines; Pregnancy; Rats; Receptors, Oxytocin; Structure-Activity Relationship; Tocolytic Agents; Uterine Contraction | 1994 |
Prevention of cannabinoid withdrawal syndrome by lithium: involvement of oxytocinergic neuronal activation.
Topics: Animals; Behavior, Animal; Brain; Camphanes; Cannabinoids; Densitometry; Dose-Response Relationship, Drug; Dronabinol; Immunohistochemistry; In Situ Hybridization; Lithium; Male; Morpholines; Neurons; Oxytocin; Piperazines; Proto-Oncogene Proteins c-fos; Pyrazoles; Radioimmunoassay; Rats; Rats, Long-Evans; Receptors, Cannabinoid; Receptors, Drug; Receptors, Oxytocin; Substance Withdrawal Syndrome | 2001 |
Attenuation of PGF2alpha release in ewes infused with the oxytocin antagonist L-368,899.
Topics: Animals; Camphanes; Corpus Luteum; Dinoprost; Dose-Response Relationship, Drug; Estrous Cycle; Female; Luteolysis; Oxytocin; Piperazines; Progesterone; Radioimmunoassay; Sheep; Uterus | 2003 |
Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus.
Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Brain Chemistry; Camphanes; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroshock; Fear; Male; Microdialysis; Norepinephrine; Oxytocin; Piperazines; Piperidines; Potassium; Quinolones; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Oxytocin; Stimulation, Chemical; Supraoptic Nucleus; Synaptosomes | 2003 |
Peripherally administered non-peptide oxytocin antagonist, L368,899, accumulates in limbic brain areas: a new pharmacological tool for the study of social motivation in non-human primates.
Topics: Amygdala; Animals; Blood-Brain Barrier; Camphanes; Female; Frontal Lobe; Hippocampus; Hormone Antagonists; Hypothalamus; Limbic System; Macaca mulatta; Male; Maternal Behavior; Oxytocin; Piperazines; Septum of Brain; Sexual Behavior, Animal | 2007 |
Oxytocin and carbetocin effects on spontaneous behavior of male rats: modulation by oxytocin receptor antagonists.
Topics: Analysis of Variance; Animals; Behavior, Animal; Camphanes; Dose-Response Relationship, Drug; Grooming; Hormone Antagonists; Male; Motor Activity; Oxytocics; Oxytocin; Piperazines; Rats; Rats, Wistar; Receptors, Oxytocin; Restraint, Physical; Stress, Physiological; Stress, Psychological; Vasotocin | 2009 |
Manipulation of the oxytocin system alters social behavior and attraction in pair-bonding primates, Callithrix penicillata.
Topics: Animals; Callithrix; Camphanes; Central Nervous System Agents; Female; Housing, Animal; Male; Oxytocin; Pair Bond; Piperazines; Receptors, Oxytocin; Sexual Behavior, Animal; Social Behavior; Time Factors | 2010 |
The fat-induced satiety factor oleoylethanolamide suppresses feeding through central release of oxytocin.
Topics: Animals; Camphanes; Dose-Response Relationship, Drug; Drug Administration Routes; Endocannabinoids; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oleic Acids; Oxytocin; Paraventricular Hypothalamic Nucleus; Piperazines; PPAR alpha; Rats; Rats, Wistar; RNA, Messenger; Supraoptic Nucleus | 2010 |
Molecular, immunohistochemical, and pharmacological evidence of oxytocin's role as inhibitor of carbohydrate but not fat intake.
Topics: Animals; Appetite Regulation; Camphanes; Dietary Carbohydrates; Dietary Fats; Down-Regulation; Eating; Feeding Behavior; Hormone Antagonists; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxytocin; Piperazines; Receptors, Oxytocin | 2010 |
Oxytocin action in the ventral tegmental area affects sucrose intake.
Topics: Analysis of Variance; Animals; Camphanes; Dose-Response Relationship, Drug; Drinking; Eating; Male; Oxytocics; Oxytocin; Piperazines; Rats; Rats, Wistar; Receptors, Oxytocin; Sucrose; Ventral Tegmental Area | 2013 |
Oxytocin receptor blockade reduces acquisition but not retrieval of taste aversion and blunts responsiveness of amygdala neurons to an aversive stimulus.
Topics: Administration, Oral; Amygdala; Animals; Brain Mapping; Camphanes; Conditioning, Psychological; Hypothalamus; Injections, Intraperitoneal; Lithium Chloride; Male; Mice; Mice, Inbred C57BL; Neurons; Oxytocin; Piperazines; Receptors, Oxytocin; Saccharin; Taste | 2013 |
Peripheral administration of oxytocin increases social affiliation in the naked mole-rat (Heterocephalus glaber).
Topics: Animals; Behavior, Animal; Camphanes; Dominance-Subordination; Female; Male; Mole Rats; Oxytocin; Piperazines; Receptors, Oxytocin; Social Behavior | 2014 |
Functional relationship between oxytocin and appetite for carbohydrates versus saccharin.
Topics: Animals; Appetite; Camphanes; Central Nervous System Agents; Choice Behavior; Dietary Carbohydrates; Dose-Response Relationship, Drug; Food Preferences; Hypothalamus; Male; Mice, Inbred C57BL; Oxytocin; Piperazines; Receptors, Oxytocin; RNA, Messenger; Saccharin | 2014 |
Oxytocin facilitates fidelity in well-established marmoset pairs by reducing sociosexual behavior toward opposite-sex strangers.
Topics: Administration, Intranasal; Animals; Callithrix; Camphanes; Female; Male; Oxytocin; Pair Bond; Piperazines; Sex Characteristics; Sexual Behavior, Animal; Social Behavior | 2014 |
Oxytocin microinjected into the central amygdaloid nuclei exerts anti-aggressive effects in male rats.
Topics: Aggression; Animals; Camphanes; Catheters, Indwelling; Central Amygdaloid Nucleus; Central Nervous System Agents; Dorsal Raphe Nucleus; Male; Microinjections; Oxytocin; Piperazines; Random Allocation; Rats; Receptors, Oxytocin | 2015 |
Effect of oxytocin receptor blockade on appetite for sugar is modified by social context.
Topics: Animals; Appetite; Behavior, Animal; Camphanes; Dietary Sucrose; Feeding Behavior; Food Preferences; Gene Expression; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Oxytocin; Piperazines; Receptors, Oxytocin; RNA, Messenger; Social Behavior; Social Dominance; Solutions; Sucrose | 2015 |
Endocannabinoid signaling mediates oxytocin-driven social reward.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Autism Spectrum Disorder; Benzamides; Benzodiazepines; Camphanes; Carbamates; Clozapine; Cocaine; Endocannabinoids; Immunohistochemistry; Infusions, Intraventricular; Lipids; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Oxytocin; Piperazines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Reward; Signal Transduction; Social Behavior | 2015 |
Oxytocin Protects Hippocampal Memory and Plasticity from Uncontrollable Stress.
Topics: Animals; Camphanes; Electroshock; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Neuronal Plasticity; Oxytocin; Piperazines; Rats; Receptors, Oxytocin; Spatial Memory | 2015 |
Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake.
Topics: Animals; Appetite; Camphanes; Eating; Feeding Behavior; Food Deprivation; Male; Microinjections; Neurons; Nucleus Accumbens; Oxytocin; Paraventricular Hypothalamic Nucleus; Piperazines; Rats; Social Behavior; Supraoptic Nucleus | 2016 |
Oxytocin reversed MK-801-induced social interaction and aggression deficits in zebrafish.
Topics: Aggression; Animals; Camphanes; Dizocilpine Maleate; Models, Animal; Neurotransmitter Agents; Oxytocin; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Oxytocin; Zebrafish | 2016 |
Oxytocin, social factors, and the expression of conditioned disgust (anticipatory nausea) in male rats.
Topics: Animals; Avoidance Learning; Behavior, Animal; Camphanes; Conditioning, Psychological; Facial Expression; Lithium Chloride; Male; Nausea; Oxytocin; Piperazines; Rats; Rats, Long-Evans; Social Behavior; Vomiting, Anticipatory | 2016 |
Neonatal oxytocin and vasopressin manipulation alter social behavior during the juvenile period in Mongolian gerbils.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Behavior, Animal; Camphanes; Gerbillinae; Indoles; Oxytocin; Piperazines; Pyrrolidines; Receptors, Oxytocin; Social Behavior; Vasopressins | 2017 |
An eye tracking system for monitoring face scanning patterns reveals the enhancing effect of oxytocin on eye contact in common marmosets.
Topics: Animals; Attention; Behavior, Animal; Callithrix; Camphanes; Communication; Eye; Eye Movements; Face; Facial Recognition; Fixation, Ocular; Oxytocin; Piperazines; Social Behavior | 2017 |
Peripheral oxytocin receptors inhibit the nociceptive input signal to spinal dorsal horn wide-dynamic-range neurons.
Topics: Action Potentials; Animals; Calcitonin Gene-Related Peptide; Camphanes; Dose-Response Relationship, Drug; Electric Stimulation; Formaldehyde; Lectins; Male; Nerve Fibers, Unmyelinated; Nociception; Oxytocin; Pain Measurement; Piperazines; Posterior Horn Cells; Psychomotor Performance; Rats; Rats, Wistar; Receptors, Oxytocin; Spinal Cord; Time Factors | 2017 |
Oxytocin Receptors in the Anteromedial Bed Nucleus of the Stria Terminalis Promote Stress-Induced Social Avoidance in Female California Mice.
Topics: Animals; Behavior, Animal; Camphanes; Disease Models, Animal; Female; Male; Mice; Nucleus Accumbens; Oxytocin; Piperazines; Receptors, Oxytocin; Septal Nuclei; Sex Characteristics; Social Behavior; Stress, Psychological | 2018 |
Oxytocin inhibits the rat medullary dorsal horn Sp5c/C1 nociceptive transmission through OT but not V
Topics: Action Potentials; Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Camphanes; Dose-Response Relationship, Drug; Electric Stimulation; Indoles; Male; Nerve Fibers; Nociceptors; Oxytocics; Oxytocin; Piperazines; Pyrrolidines; Rats; Rats, Wistar; Receptors, Oxytocin; Receptors, Vasopressin; Spinal Cord Dorsal Horn | 2018 |
Oxytocin administration in the basolateral and central nuclei of amygdala moderately suppresses food intake.
Topics: Animals; Avoidance Learning; Basolateral Nuclear Complex; Camphanes; Central Amygdaloid Nucleus; Drinking; Eating; Food Deprivation; Male; Oxytocics; Oxytocin; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; RNA, Messenger; Taste | 2018 |
Central oxytocin signaling mediates the central orexin-induced visceral antinociception through the opioid system in conscious rats.
Topics: Adenosine A1 Receptor Antagonists; Analgesics; Animals; Camphanes; Cannabinoid Receptor Agonists; Dopamine D2 Receptor Antagonists; Hormone Antagonists; Indoles; Male; Naloxone; Narcotic Antagonists; Nociception; Oxytocin; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; Reflex; Sulpiride; Xanthines | 2019 |
Behavioral and cardiovascular consequences of disrupted oxytocin communication in cohabitating pairs of male and female prairie voles.
Topics: Animals; Arvicolinae; Blood Pressure; Camphanes; Female; Heart Rate; Male; Oxytocin; Pair Bond; Piperazines; Social Behavior | 2019 |
Effects of oxytocin receptor antagonism on social function and corticosterone release after adolescent social instability in male rats.
Topics: Animals; Behavior, Animal; Brain; Camphanes; Corticosterone; Hypothalamo-Hypophyseal System; Male; Oxytocin; Paraventricular Hypothalamic Nucleus; Piperazines; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Long-Evans; Receptors, Oxytocin; Sexual Maturation; Social Behavior; Stress, Psychological | 2019 |
Oxytocin maintains lung histological and functional integrity to confer protection in heat stroke.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Camphanes; Cytokines; Disease Models, Animal; Fever; Heat Stroke; Heat-Shock Response; Hypotension; Lung; Male; Neutrophil Infiltration; Oxytocin; Peroxidase; Piperazines; Protective Agents; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; Survival Analysis | 2019 |
Oxytocin Receptors Regulate Social Preference in Zebrafish.
Topics: Animals; Camphanes; HEK293 Cells; Humans; Models, Animal; Models, Psychological; Oxytocin; Piperazines; Receptors, Oxytocin; Social Behavior; Vasotocin; Zebrafish | 2020 |
Activation of oxytocin receptor in the trigeminal ganglion attenuates orofacial ectopic pain attributed to inferior alveolar nerve injury.
Topics: Animals; Calcitonin Gene-Related Peptide; Camphanes; Interleukin-1beta; Male; Mandibular Nerve Injuries; Oxytocin; Pain; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; Trigeminal Ganglion; Tumor Necrosis Factor-alpha | 2021 |