ixazomib and ubenimex
ixazomib has been researched along with ubenimex* in 1 studies
Other Studies
1 other study(ies) available for ixazomib and ubenimex
| Article | Year |
|---|---|
Discovery of a Novel Ubenimex Derivative as a First-in-Class Dual CD13/Proteasome Inhibitor for the Treatment of Cancer.
The CD13 inhibitor ubenimex is used as an adjuvant drug with chemotherapy for the treatment of cancer due to its function as an immunoenhancer, but it has limitations in its cytotoxic efficacy. The proteasome inhibitor ixazomib is a landmark drug in the treatment of multiple myeloma with a high anti-cancer activity. Herein, we conjugated the pharmacophore of ubenimex and the boric acid of ixazomib to obtain a dual CD13 and proteasome inhibitor Topics: Antiviral Agents; Enzyme Therapy; Humans; Multiple Myeloma; Proteasome Inhibitors | 2023 |