isoxazoles and lysine
isoxazoles has been researched along with lysine in 13 studies
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Roby, KA; Segal, S | 1 |
| Baccanari, DP; Delcamp, TJ; Forsch, RA; Freisheim, JH; Rosowsky, A; Solan, VC | 1 |
| Bulut, D; Hanefeld, C; Koll, R; Liaghat, S; Miebach, T; Mügge, A | 1 |
| Behr, B; Hoffmann, C; Klotz, KN; Ottolina, G | 1 |
| Knauf, PA; Lebedev, D; Pal, P; Salim, S | 1 |
| Salzberg, DJ; Weir, MR | 1 |
| Huntsman, MM; Krook-Magnuson, EI; Li, P; Paluszkiewicz, SM | 1 |
| Conway, SJ; Fedorov, O; Filippakopoulos, P; Heightman, TD; Hewings, DS; Knapp, S; Marsden, B; Philpott, M; Picaud, S; Uttarkar, S; Vuppusetty, C; Wang, M | 1 |
| Brennan, PE; Conway, SJ; Fedorov, O; Filippakopoulos, P; Freeman, K; Gill, A; Hammond, EM; Hewings, DS; Knapp, S; Martin, S; Olcina, MM; Picaud, S; Ritchie, AJ; Russell, AJ; Sheppard, DW; Tumber, A; Wells, C | 1 |
| Abburi, C; Gallagher, K; McDaid, J; McGehee, DS; Wolfman, SL | 1 |
| Chen, P; Fung, H; Gu, Y; He, S; Hexner, E; Hu, S; Huang, J; Huang, Q; Jin, J; Jin, M; Li, C; Liu, Y; Ma, A; Reshef, R; Tian, Y; Tong, Q; Yu, H; Zhang, Y | 1 |
| Channe Gowda, D; Kumara, HK; Pavan Kumar, H; Suhas, R | 1 |
| Bruyère, D; Coles, SJ; Edmonds, AK; Felix, R; Hassell-Hart, S; Maple, HJ; Marsh, GP; Oakes, CS; Spencer, J; Tizzard, GJ | 1 |
Reviews
1 review(s) available for isoxazoles and lysine
| Article | Year |
|---|---|
COX-2 inhibitors and cardiovascular risk.
Topics: Blood Pressure; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Lactones; Lysine; Risk Factors; Sulfonamides; Sulfones; Water-Electrolyte Balance | 2007 |
Trials
1 trial(s) available for isoxazoles and lysine
| Article | Year |
|---|---|
Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension.
Topics: Acetylcholine; Adult; Aged; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Isoenzymes; Isoxazoles; Lysine; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Regional Blood Flow; Vasodilation; Vasodilator Agents | 2003 |
Other Studies
11 other study(ies) available for isoxazoles and lysine
| Article | Year |
|---|---|
Cystine and lysine reabsorption in the isolated perfused rat kidney.
Topics: Amino Acids; Animals; Cystine; gamma-Glutamyltransferase; Glutathione; In Vitro Techniques; Isoxazoles; Kidney; Lysine; Male; Perfusion; Rats; Rats, Inbred Strains | 1989 |
Methotrexate analogues. 30. Dihydrofolate reductase inhibition and in vitro tumor cell growth inhibition by N epsilon-(haloacetyl)-L-lysine and N delta-(haloacetyl)-L-ornithine analogues and an acivicin analogue of methotrexate.
Topics: Acetates; Animals; Candida albicans; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Isoxazoles; Leukemia L1210; Lysine; Methotrexate; Mice; NADP; Ornithine; Protein Conformation; Spectrophotometry | 1987 |
Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Aspartic Acid; CHO Cells; Cricetinae; Humans; Isoleucine; Isoxazoles; Ligands; Lysine; Molecular Sequence Data; Mutagenesis; Protein Structure, Secondary; Protein Structure, Tertiary; Radioligand Assay; Receptors, Adrenergic, beta-1; Terbutaline; Valine | 2006 |
Substrates induce conformational changes in human anion exchanger 1 (hAE1) as observed by fluorescence resonance energy transfer.
Topics: Anion Exchange Protein 1, Erythrocyte; Barbiturates; Binding Sites; Energy Transfer; Erythrocyte Membrane; Erythrocytes; Fluoresceins; Fluorescence Resonance Energy Transfer; Humans; Ion Transport; Isoxazoles; Lysine; Models, Biological; Protein Binding; Protein Conformation; Substrate Specificity; Thermodynamics; Thiobarbiturates | 2006 |
Tonically active inhibition selectively controls feedforward circuits in mouse barrel cortex.
Topics: Action Potentials; Animals; Cerebral Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Female; GABA Agonists; In Vitro Techniques; Isoxazoles; Lysine; Male; Mice; Mice, Inbred C57BL; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Receptors, GABA-A; Thalamus | 2008 |
3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands.
Topics: Cell Cycle Proteins; CREB-Binding Protein; Crystallography, X-Ray; Cytotoxins; HeLa Cells; Histones; Humans; Isoxazoles; Ligands; Lysine; Models, Molecular; Molecular Mimicry; Molecular Structure; Nuclear Proteins; Phenylethyl Alcohol; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Stereoisomerism; Structure-Activity Relationship; Transcription Factors | 2011 |
Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands.
Topics: Acetylation; Cell Cycle Proteins; Cell Line, Tumor; CREB-Binding Protein; Crystallography, X-Ray; Histones; Humans; Inhibitory Concentration 50; Isoxazoles; Ligands; Lysine; Nuclear Proteins; Protein Binding; Structure-Activity Relationship; Transcription Factors | 2013 |
Ethanol-Induced Motor Impairment Mediated by Inhibition of α7 Nicotinic Receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Central Nervous System Depressants; Cholinergic Agents; Cholinesterases; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Lysine; Male; Motor Disorders; Neurotransmitter Agents; Phenylurea Compounds; Phosphorylation; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Potentials | 2016 |
Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice.
Topics: Animals; Enhancer of Zeste Homolog 2 Protein; Graft vs Host Disease; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Histones; HSP90 Heat-Shock Proteins; Indoles; Isoxazoles; Lysine; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Protein Domains; Protein Stability; Pyridones; Resorcinols; T-Lymphocytes; Transplantation, Homologous | 2017 |
Multitarget-directed therapeutics: (Urea/thiourea)
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Heterocyclic Compounds; Humans; Isoxazoles; Lysine; Molecular Docking Simulation; Piperazines; Piperidines; Structure-Activity Relationship; Thiourea; Urea | 2021 |
Scale-up and optimization of the synthesis of dual CBP/BRD4 inhibitor ISOX-DUAL.
Topics: Cell Cycle Proteins; Isoxazoles; Lysine; Nuclear Proteins; Protein Domains; Transcription Factors | 2022 |