isoxazoles and cx717
isoxazoles has been researched along with cx717 in 17 studies
Research
Studies (17)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 5 (29.41) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Deadwyler, SA; España, RA; Hampson, RE; Porrino, LJ; Rogers, GA | 1 |
| Greer, JJ; Ren, J | 1 |
| Angst, MS; Bradshaw, MH; Felden, L; Geisslinger, G; Greer, JJ; Johnson, S; Lötsch, J; Oertel, BG; Schmidt, H; Tran, PV; Varney, MA | 1 |
| Arbon, EL; Boyle, J; Dijk, DJ; James, LM; Johnsen, S; Stanley, N; Wright, N | 1 |
| Balabhadrapatruni, S; Darlington, CL; Masumura, C; Smith, PF; Zheng, Y | 1 |
| Ding, X; Greer, JJ; Ren, J | 1 |
| Ding, X; Greer, JJ; Lenal, F; Ren, J; Yang, M | 1 |
| Aarts, L; Dahan, A; Roozekrans, M; Smith, T; van der Schrier, R | 1 |
| Byrne, BJ; Cerreta, AJ; ElMallah, MK; Falk, DJ; Fuller, DD; Greer, JJ; Pagliardini, S; Turner, SM | 1 |
| Einat, H; Flaisher-Grinberg, S; Kara, NZ | 1 |
| ElMallah, MK; Fuller, DD; Greer, JJ; Hoyt, AK; Turner, SM | 1 |
| Bolon, B; Cook, J; Gall, C; Garman, RH; Johnson, S; Jortner, B; Lippa, A; Lynch, G; Purcell, R; Radin, D; Sheng, Z; Stephen, MR | 1 |
| Adell, A; Gordillo-Salas, M; Greer, J; Pascual-Antón, R; Ren, J | 1 |
| Fuller, DD; Fusco, AF; Gonzalez-Rothi, EJ; Greer, JJ; Sandhu, MS; Streeter, KA; Wollman, LB | 1 |
| Fuller, DD; Sunshine, MD; Thakre, PP | 2 |
| Fuller, DD; Greer, JJ; Rana, S; Sunshine, MD | 1 |
Trials
2 trial(s) available for isoxazoles and cx717
| Article | Year |
|---|---|
Selective antagonism of opioid-induced ventilatory depression by an ampakine molecule in humans without loss of opioid analgesia.
Topics: Administration, Oral; Adult; Alfentanil; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Humans; Hypercapnia; Isoxazoles; Male; Naloxone; Narcotic Antagonists; Oxygen; Pain; Respiratory Insufficiency; Young Adult | 2010 |
Acute sleep deprivation: the effects of the AMPAKINE compound CX717 on human cognitive performance, alertness and recovery sleep.
Topics: Adolescent; Adult; Allosteric Regulation; Arousal; Brain Waves; Cognition Disorders; Cross-Over Studies; Dose-Response Relationship, Drug; Electroencephalography; Humans; Isoxazoles; Male; Middle Aged; Nootropic Agents; Polysomnography; Psychomotor Performance; Receptors, AMPA; Sleep; Sleep Deprivation; Wakefulness | 2012 |
Other Studies
15 other study(ies) available for isoxazoles and cx717
| Article | Year |
|---|---|
Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717.
Topics: Animals; Brain Chemistry; Calcium; Cognition; Cognition Disorders; Electrophysiology; Glucose; Hippocampus; Image Processing, Computer-Assisted; Isoxazoles; Macaca mulatta; Male; Microscopy, Confocal; Neurons; Nootropic Agents; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sleep Deprivation; Synapses | 2009 |
Ampakine therapy to counter fentanyl-induced respiratory depression.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Drug Administration Schedule; Fentanyl; Heart Rate; Hyperalgesia; Isoxazoles; Male; Pain Measurement; Phrenic Nerve; Plethysmography; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Respiratory Insufficiency; Time Factors | 2009 |
Effects of the putative cognitive-enhancing ampakine, CX717, on attention and object recognition memory.
Topics: Animals; Attention; Cognition; Cognition Disorders; Disease Models, Animal; Isoxazoles; Male; Memory; Memory Disorders; Neural Inhibition; Nootropic Agents; Rats; Rats, Wistar; Reaction Time; Recognition, Psychology; Time Factors; Treatment Outcome; Vestibular Diseases | 2011 |
Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717.
Topics: Animals; Apnea; Barbiturates; Brain Stem; Ethanol; Hypercapnia; Hypoxia; Isoxazoles; Male; Oxygen; Plethysmography; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Respiratory Insufficiency; Spinal Cord | 2012 |
Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneas.
Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Apnea; Disease Models, Animal; Drug Therapy, Combination; Isoxazoles; Male; Mice; Plethysmography; Propofol; Rats; Rats, Sprague-Dawley; Respiratory Insufficiency | 2013 |
Primum non nocere or how to resolve drug-induced respiratory depression.
Topics: Anesthetics, Intravenous; Animals; Apnea; Isoxazoles; Male; Propofol; Respiratory Insufficiency | 2013 |
Stimulation of Respiratory Motor Output and Ventilation in a Murine Model of Pompe Disease by Ampakines.
Topics: Animals; Brain Stem; Drug Evaluation, Preclinical; Glycogen Storage Disease Type II; Isoxazoles; Mice, 129 Strain; Mice, Knockout; Motor Activity; Phrenic Nerve; Respiration; Respiratory System Agents | 2015 |
Partial effects of the AMPAkine CX717 in a strain specific battery of tests for manic-like behavior in black Swiss mice.
Topics: Aggression; Amphetamine; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Isoxazoles; Male; Mice; Motor Activity; Receptors, AMPA; Swimming | 2015 |
Ampakine CX717 potentiates intermittent hypoxia-induced hypoglossal long-term facilitation.
Topics: Action Potentials; Animals; Hypoglossal Nerve; Hypoxia; Isoxazoles; Long-Term Potentiation; Male; Mice, 129 Strain; Models, Animal; Neurological Rehabilitation; Peripheral Nervous System Agents; Respiration; Respiration, Artificial | 2016 |
Brain Vacuolation Resulting From Administration of the Type II Ampakine CX717 Is An Artifact Related to Molecular Structure and Chemical Reaction With Tissue Fixative Agents.
Topics: Animals; Artifacts; Astrocytes; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Female; Fixatives; In Vitro Techniques; Isoxazoles; Macaca fascicularis; Male; Molecular Structure; Patch-Clamp Techniques; Photomicrography; Rats, Sprague-Dawley; Synaptic Potentials; Vacuoles | 2018 |
Antidepressant-Like Effects of CX717, a Positive Allosteric Modulator of AMPA Receptors.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cell-Penetrating Peptides; Depression; Glutamic Acid; Isoxazoles; Male; Rats, Sprague-Dawley; Receptors, AMPA; Serotonin | 2020 |
Ampakines stimulate phrenic motor output after cervical spinal cord injury.
Topics: Animals; Cervical Vertebrae; Diaphragm; Isoxazoles; Male; Motor Neurons; Organ Culture Techniques; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries | 2020 |
Ampakine pretreatment enables a single hypoxic episode to produce phrenic motor facilitation with no added benefit of additional episodes.
Topics: Animals; Hypoxia; Isoxazoles; Male; Neuronal Plasticity; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors | 2021 |
Spinally delivered ampakine CX717 increases phrenic motor output in adult rats.
Topics: Animals; Arterial Pressure; Diaphragm; Heart Rate; Injections, Spinal; Isoxazoles; Male; Neuronal Plasticity; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2022 |
Ampakines Stimulate Diaphragm Activity after Spinal Cord Injury.
Topics: Animals; Cervical Cord; Cervical Vertebrae; Diaphragm; Electromyography; Female; Isoxazoles; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord Injuries | 2021 |