Page last updated: 2024-08-24

irinotecan and serine

irinotecan has been researched along with serine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frank, C; Hapke, G; Rustum, YM; Wu, J; Yin, MB1
Morton, CL; Nguyen, NK; Potter, PM; Redinbo, MR; Wierdl, M1
Arakawa, Y; Saito, S; Suzuki, H; Yamada, H1
Gjerset, RA; Zhao, M1

Other Studies

4 other study(ies) available for irinotecan and serine

ArticleYear
Phosphorylation of chk1 at serine-345 affected by topoisomerase I poison SN-38.
    International journal of oncology, 2002, Volume: 21, Issue:5

    Topics: 14-3-3 Proteins; Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Camptothecin; Carrier Proteins; cdc25 Phosphatases; Cell Cycle Proteins; Checkpoint Kinase 1; DNA Damage; DNA Fragmentation; DNA-Binding Proteins; Enzyme Inhibitors; G2 Phase; Head and Neck Neoplasms; Humans; Irinotecan; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins; Serine; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

2002
Molecular modeling of CPT-11 metabolism by carboxylesterases (CEs): use of pnb CE as a model.
    Biochemistry, 2004, Feb-24, Volume: 43, Issue:7

    Topics: Animals; Arginine; Bacillus subtilis; Bacterial Proteins; Camptothecin; Carboxylic Ester Hydrolases; Catalysis; Computer Simulation; COS Cells; DNA Mutational Analysis; Humans; Irinotecan; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Rabbits; Serine; Viscosity

2004
Novel missense mutation of the DNA topoisomerase I gene in SN-38-resistant DLD-1 cells.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:3

    Topics: Amino Acid Substitution; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Glycine; Humans; Irinotecan; Mutation, Missense; Protein Conformation; Serine

2006
Topoisomerase-I PS506 as a Dual Function Cancer Biomarker.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Amino Acid Sequence; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colonic Neoplasms; DNA Topoisomerases, Type I; Female; Gene Expression; Humans; Irinotecan; Lung; Lung Neoplasms; Molecular Sequence Data; Neoplasms; Ovarian Neoplasms; Phosphorylation; Serine; Topotecan

2015