Compounds > indazoles
Page last updated: 2024-08-21

indazoles and y 27632

indazoles has been researched along with y 27632 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adam, J; Bennett, J; Black, D; Boucharens, S; Brown, AR; Cook, A; de Man, J; Epemolu, O; Fletcher, D; Haunso, A; Huggett, M; Jones, P; Laats, S; Lyons, A; Mestres, J; Morphy, R; Rankovic, Z; Ray, P; Sherborne, B; Sherry, L; van Straten, N; Westwood, P; Wright, J; Zaman, GZ1
Cheng, CY; Lee, WM; Lui, WY1
Abraham, A; Adams, DR; Allcock, RW; Andrews, PD; Aspegren, A; Becroft, M; Frearson, JA; Gilmour, J; Houslay, MD; James, MJ; Jiang, Z; Kime, R; McRae, S; Milligan, G; Mountford, JC; Strehl, R1
Chou, AH; Hu, SH; Wang, HL; Wang, SS; Weng, YH; Yeh, TH1
Allain, AV; Kadowitz, PJ; Lasker, GF; Murthy, SN; Pankey, EA; Stasch, JP1
Borchiellini, C; Fierro-Constain, L; Hall, C; Hill, AL; Quintero, O; Renard, E; Schenkelaars, Q1

Other Studies

6 other study(ies) available for indazoles and y 27632

ArticleYear
Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Amines; Animals; Binding Sites; Computer Simulation; Crystallography, X-Ray; Drug Evaluation, Preclinical; Isoquinolines; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; rho-Associated Kinases; Structure-Activity Relationship

2011
Sertoli-germ cell adherens junction dynamics in the testis are regulated by RhoB GTPase via the ROCK/LIMK signaling pathway.
    Biology of reproduction, 2003, Volume: 68, Issue:6

    Topics: Adherens Junctions; Algorithms; Amides; Animals; Brain; Cells, Cultured; Coculture Techniques; Germ Cells; GTP Phosphohydrolases; Hydrazines; Immunoblotting; Immunohistochemistry; Indazoles; Intracellular Signaling Peptides and Proteins; Kidney; Male; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoB GTP-Binding Protein; RNA, Messenger; Seminiferous Epithelium; Sertoli Cells; Signal Transduction; Testis

2003
High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules.
    The Biochemical journal, 2010, Nov-15, Volume: 432, Issue:1

    Topics: Amides; Cell Culture Techniques; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Embryonic Stem Cells; Heterocyclic Compounds; Humans; Indazoles; Molecular Structure; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Time Factors

2010
H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse.
    Neuropharmacology, 2013, Volume: 70

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Ataxin-3; Ataxin-7; Brain; Dose-Response Relationship, Drug; Gene Expression; Humans; Indazoles; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Niacinamide; Nuclear Proteins; Peptides; Proteasome Endopeptidase Complex; Pyridines; rho-Associated Kinases; Transcription Factors

2013
The selective Rho-kinase inhibitor azaindole-1 has long-lasting erectile activity in the rat.
    Urology, 2013, Volume: 81, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Area Under Curve; Atropine; Blood Pressure; Diamines; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Male; Muscarinic Antagonists; Nitric Oxide; Oxadiazoles; Penile Erection; Penis; Peripheral Nerve Injuries; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; rho-Associated Kinases; Signal Transduction; Time Factors

2013
ROCK inhibition abolishes the establishment of the aquiferous system in Ephydatia muelleri (Porifera, Demospongiae).
    Developmental biology, 2016, Apr-15, Volume: 412, Issue:2

    Topics: Amides; Animals; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Indazoles; Morphogenesis; Niacinamide; Phylogeny; Porifera; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Species Specificity

2016