Page last updated: 2024-08-21

indazoles and epz-6438

indazoles has been researched along with epz-6438 in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Beijnen, JH; Buil, LC; de Gooijer, MC; Li, G; van Tellingen, O; Zhang, P	1
Kim, KH; Roberts, CW	1
Carcaboso, AM; Comet, I; de Torres, C; Helin, K; Højfeldt, JW; Jensen, ON; Johansen, JV; Lavarino, C; Leblanc, B; Mohammad, F; Mora, J; Olaciregui, NG; Pandey, DP; Porse, BT; Rapin, N; Suñol, M; Tvardovskiy, A; Weissmann, S; Zheng, C	1

Reviews

1 review(s) available for indazoles and epz-6438

Article	Year
Targeting EZH2 in cancer. Nature medicine, 2016, Volume: 22, Issue:2 Topics: Benzamides; Biphenyl Compounds; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Humans; Indazoles; Indoles; Molecular Targeted Therapy; Morpholines; Mutation; Neoplasms; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Pyridones	2016

Other Studies

2 other study(ies) available for indazoles and epz-6438

Article	Year
ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors. International journal of cancer, 2015, Oct-15, Volume: 137, Issue:8 Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Benzamides; Biological Availability; Biphenyl Compounds; Blood-Brain Barrier; Cell Line; Dogs; Drug Evaluation, Preclinical; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Humans; Indazoles; Indoles; Madin Darby Canine Kidney Cells; Mice; Mice, Knockout; Morpholines; Polycomb Repressive Complex 2; Pyridones	2015
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas. Nature medicine, 2017, Volume: 23, Issue:4 Topics: Animals; Benzamides; Biphenyl Compounds; Brain Neoplasms; Brain Stem Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Chromatography, Liquid; CRISPR-Cas Systems; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Gene Knockout Techniques; Glioblastoma; Glioma; Histones; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Indazoles; Mice; Mice, SCID; Molecular Targeted Therapy; Morpholines; Mutation; Neoplasm Transplantation; Neural Stem Cells; Polycomb Repressive Complex 2; Pyridones; Tandem Mass Spectrometry; Tumor Suppressor Protein p14ARF	2017

Article

Year

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

International journal of cancer, 2015, Oct-15, Volume: 137, Issue:8

Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Benzamides; Biological Availability; Biphenyl Compounds; Blood-Brain Barrier; Cell Line; Dogs; Drug Evaluation, Preclinical; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Humans; Indazoles; Indoles; Madin Darby Canine Kidney Cells; Mice; Mice, Knockout; Morpholines; Polycomb Repressive Complex 2; Pyridones

2015

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.

Nature medicine, 2017, Volume: 23, Issue:4

Topics: Animals; Benzamides; Biphenyl Compounds; Brain Neoplasms; Brain Stem Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Chromatography, Liquid; CRISPR-Cas Systems; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Gene Knockout Techniques; Glioblastoma; Glioma; Histones; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Indazoles; Mice; Mice, SCID; Molecular Targeted Therapy; Morpholines; Mutation; Neoplasm Transplantation; Neural Stem Cells; Polycomb Repressive Complex 2; Pyridones; Tandem Mass Spectrometry; Tumor Suppressor Protein p14ARF

2017