imipramine and mannitol

imipramine has been researched along with mannitol in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's1 (5.26)18.2507
2000's5 (26.32)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Faassen, F; Spanings, H; Vogel, G; Vromans, H1
Caron, G; Ermondi, G1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Connor, JD; Crawford, IL; Pardridge, WM1
Burberi, P; Piccinelli, D; Silvestrini, B1
David, L; Fayard, C; Monnet, P; Robin, JY; Rosenberg, D1
Masters, AB1
Lock, S; Plaa, GL; Witschi, H1
Nadai, T; Sakane, T; Taki, Y; Yamashita, S; Yoshida, M1
HARTHORNE, JW; KAYE, M; MARCUS, AM1

Reviews

1 review(s) available for imipramine and mannitol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for imipramine and mannitol

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
    International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport

2003
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Permeability changes in the blood-brain barrier induced by nortriptyline and chlorpromazine.
    Toxicology and applied pharmacology, 1973, Volume: 26, Issue:1

    Topics: Amitriptyline; Animals; Autoradiography; Blood-Brain Barrier; Brain; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Cerebral Cortex; Chlorpromazine; Desipramine; Diphenhydramine; Dopamine; Imipramine; In Vitro Techniques; Inulin; Male; Mannitol; Molecular Weight; Nortriptyline; Rats; Tritium

1973
Effects of systemically administered drugs on intraocular pressure in rabbits.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Acetazolamide; Amphetamine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Carotid Arteries; Chlordiazepoxide; Chlorothiazide; Chlorpromazine; Depression, Chemical; Dichlorphenamide; Female; Glycerol; Guanethidine; Hexamethonium Compounds; Imipramine; Intraocular Pressure; Iproniazid; Male; Mannitol; Phenoxybenzamine; Phenylbutazone; Pilocarpine; Pyridines; Rabbits; Stimulation, Chemical; Urea

1970
[Poisoning by imipramine and its derivatives in pediatrics. Apropos of 4 cases].
    La Presse medicale, 1969, Sep-27, Volume: 77, Issue:40

    Topics: Child, Preschool; Dibenzothiazepines; Electrocardiography; Female; Gastric Lavage; Humans; Imipramine; Lactates; Male; Mannitol; Neurologic Manifestations; Sodium; Tachycardia; Ventricular Fibrillation

1969
Delayed death in imipramine poisoning.
    British medical journal, 1967, Sep-30, Volume: 3, Issue:5569

    Topics: Chlorpromazine; Female; Furosemide; Gastric Lavage; Heart Arrest; Humans; Imipramine; Infusions, Parenteral; Mannitol; Middle Aged; Paraldehyde

1967
The effect of ethanol on the absorption, accumulation and biotransformation of xenobiotics by the isolated perfused rabbit lung.
    Toxicology, 1983, Volume: 26, Issue:2

    Topics: Absorption; Aldrin; Animals; Biotransformation; Ethanol; Imipramine; Lung; Male; Mannitol; Paraquat; Perfusion; Rabbits; Sulfanilic Acids

1983
Kinetic analysis of the drug permeation process across the intestinal epithelium.
    Pharmaceutical research, 1994, Volume: 11, Issue:11

    Topics: Animals; Antipyrine; Imipramine; Intestinal Mucosa; Male; Mannitol; Permeability; Pharmacokinetics; Propranolol; Rats; Rats, Wistar; Water

1994
Management of massive imipramine overdosage with mannitol and artificial dialysis.
    The New England journal of medicine, 1963, Jan-03, Volume: 268

    Topics: Disease Management; Humans; Imipramine; Kidney; Kidneys, Artificial; Mannitol; Renal Dialysis

1963