imipramine has been researched along with ketamine in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (22.22) | 29.6817 |
| 2010's | 27 (60.00) | 24.3611 |
| 2020's | 5 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Henriksson, BG; Järbe, TU; Johansson, JO | 1 |
| Harakal, JJ; Sofia, RD | 1 |
| Ahlemeyer, B; Krieglstein, J | 1 |
| Bruins Slot, LA; Colpaert, FC; Koek, W; Ribet, JP; Tarayre, JP | 1 |
| Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Calixto, JB; Lin, J; Rodrigues, AL; Rosa, AO; Santos, AR | 1 |
| Andreazza, AC; Barbosa, LM; Comim, CM; Fries, GR; Garcia, LS; Gavioli, EC; Kapczinski, F; Quevedo, J; Réus, GZ; Stertz, L; Valvassori, SS | 1 |
| Bansal, V; Hota, D; Pattanaik, S | 1 |
| Andreazza, AC; Comim, CM; Fries, GR; Garcia, LS; Gavioli, EC; Kapczinski, F; Quevedo, J; Réus, GZ; Stertz, L; Valvassori, SS | 1 |
| Assis, LC; Comim, CM; Jeremias, IC; Quevedo, J; Rezin, GT; Streck, EL; Valvassori, SS; Zugno, AI | 1 |
| Cesconetto, P; Ferraro, AK; Quevedo, J; Réus, GZ; Ribeiro, KF; Souza, CT; Stringari, RB; Vitto, MF | 1 |
| Antila, H; Autio, H; Castrén, E; Hoener, MC; Lindemann, L; Lindholm, JS; Rantamäki, T; Skolnick, P; Vesa, L | 1 |
| Kaster, MP; Machado, DG; Rodrigues, AL; Santos, AR | 1 |
| Abelaira, HM; Barth, M; Carlessi, AS; dos Santos, MA; Gubert, C; Kapczinski, F; Liranço, JL; Neotti, MV; Quevedo, J; Réus, GZ; Tomaz, DB | 1 |
| Holland, MG; Marraffa, JM; Ryzewski, M; Sullivan, RW | 1 |
| Hillhouse, TM; Porter, JH | 1 |
| Matsumoto, RR; Nguyen, L | 1 |
| Gaweł, M; Młyniec, K; Nowak, G | 1 |
| Dalla, C; Ferreira, C; Kokras, N; Melo, A; Pêgo, JM; Sousa, N; Ventura-Silva, AP | 1 |
| Poleszak, E; Serefko, A; Wlaź, P; Wróbel, A | 1 |
| Biber, K; Clement, HW; de Bartolomeis, A; Iasevoli, F; Idzko, M; Jacobson, KA; Normann, C; Schwarz, MK; Serchov, T; Tosh, DK; van Calker, D | 1 |
| Ji, L; Li, H; Liu, W; Wang, Y | 1 |
| Jin, XJ; Li, QQ; Peng, LC; Ye, K | 1 |
| Bagot, RC; Cates, HM; Heller, EA; LaBonté, B; Nestler, EJ; Peña, CJ; Purushothaman, I; Shen, L; Vialou, V; Wittenberg, GM; Yieh, L | 1 |
| Brand, SJ; Harvey, BH | 1 |
| Gruca, P; Lason-Tyburkiewicz, M; Papp, M; Willner, P | 1 |
| Cai, X; Dong, J; Huang, M; Wei, Z; Xu, T; Zhang, K; Zheng, Y; Zhou, Q | 1 |
| Andreatini, R; Bruginski, E; Campos, FR; de Almeida Soares Hocayen, P; Kanazawa, LKS; Miyoshi, E; Schwarting, RKW; Stern, CAJ; Vecchia, DD; Vital, MABF; Wendler, E; Wöhr, M | 1 |
| Gruca, P; Lason, M; Litwa, E; Niemczyk, M; Papp, M; Tota-Glowczyk, K; Willner, P | 1 |
| Hainz, N; Kovačević, B; Meier, C; Rzagalinski, I; Tschernig, T; Volmer, DA | 1 |
| Elfving, B; Harvey, BH; Joca, SRL; Pereira, VS; Wegener, G | 1 |
| Cao, Y; Che, F; He, W; Sun, H; Wang, Y; Yao, Z; Zhang, H | 1 |
| Antonio, CB; Barbosa, AR; Borsoi, M; Lima, MS; Medeiros, I; Neves, GA; Nunes, LED; Pranke, MA; Rates, SMK | 1 |
| Andreatini, R; Da Cunha, C; Hocayen, PAS; Kanazawa, LKS; Miyoshi, E; Takahashi, RN; Vecchia, DD; Vital, MABF; Wendler, E | 1 |
| Babu, NS; Bhattacharya, D; Chakravarty, S; Das, T; Idris, MM; Kumar, A; Murthy, CLN; Reddy, BR | 1 |
1 review(s) available for imipramine and ketamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
44 other study(ies) available for imipramine and ketamine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
Drug discrimination in rats: the effects of phencyclidine and ditran.
Topics: Animals; Cues; Cyclohexylamines; Discrimination Learning; Drug Combinations; Fenclonine; Glycolates; Imipramine; Ketamine; Male; Neostigmine; Phencyclidine; Physostigmine; Piperidines; Pyrrolidines; Rats; Tacrine; Tetrabenazine; Yohimbine | 1975 |
Evaluation of ketamine HCl for anti-depressant activity.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Drug Synergism; Imipramine; Ketamine; Male; Mice; Oxotremorine; Parasympatholytics; Rats; Reserpine; Tetrabenazine; Yohimbine | 1975 |
Testing drug effects against hypoxic damage of cultured neurons during long-term recovery.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Ischemia; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Clonazepam; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Flunarizine; Haloperidol; Imipramine; Ketamine; Lidocaine; Nafronyl; Neurons; Pyrithioxin; Telencephalon | 1989 |
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine | 2002 |
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection | 2002 |
Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Behavior, Animal; Chlorides; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Free Radical Scavengers; Guanosine Monophosphate; Hindlimb Suspension; Imipramine; Immobilization; Ketamine; Male; Mice; Motor Activity; Nitric Oxide; Nitric Oxide Donors; Pain Measurement; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Swimming; Time Factors; Zinc Compounds | 2003 |
Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Drug; Hippocampus; Imipramine; Immobility Response, Tonic; Ketamine; Male; Rats; Rats, Wistar; Swimming | 2008 |
Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Imipramine; Ketamine; Male; Nimodipine; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy | 2007 |
Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hippocampus; Imipramine; Ketamine; Male; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2008 |
Effect of acute administration of ketamine and imipramine on creatine kinase activity in the brain of rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Creatine Kinase; Depression; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Imipramine; Ketamine; Male; Rats; Rats, Wistar; Stress, Physiological | 2009 |
Ketamine plus imipramine treatment induces antidepressant-like behavior and increases CREB and BDNF protein levels and PKA and PKC phosphorylation in rat brain.
Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Imipramine; Immobility Response, Tonic; Ketamine; Motor Activity; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar | 2011 |
The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf⁺/⁻ heterozygous null mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Hippocampus; Imipramine; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reaction Time; Receptor, trkA; Sulfonamides; Swimming | 2012 |
Involvement of NMDA receptors in the antidepressant-like action of adenosine.
Topics: Adenosine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chlorides; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; Immobilization; Ketamine; Male; Mice; N-Methylaspartate; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Serine; Swimming; Time Factors; Zinc Compounds | 2012 |
Ketamine and imipramine in the nucleus accumbens regulate histone deacetylation induced by maternal deprivation and are critical for associated behaviors.
Topics: Acetylation; Amygdala; Animals; Antidepressive Agents; Behavior, Animal; Hippocampus; Histones; Imipramine; Ketamine; Male; Maternal Deprivation; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Swimming | 2013 |
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined Modality Therapy; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diaper Rash; Drug Combinations; Drug Compounding; Drug Overdose; Emergencies; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Ketamine; Lidocaine; Male; Mefenamic Acid; Ointments; Reflex, Abnormal; Respiration Disorders; Skin Absorption | 2013 |
Ketamine, but not MK-801, produces antidepressant-like effects in rats responding on a differential-reinforcement-of-low-rate operant schedule.
Topics: Animals; Antidepressive Agents; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Excitatory Amino Acid Antagonists; Imipramine; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology | 2014 |
Involvement of AMPA receptors in the antidepressant-like effects of dextromethorphan in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hindlimb Suspension; Imipramine; Ketamine; Male; Mice; Quinidine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Swimming | 2015 |
Study of antidepressant drugs in GPR39 (zinc receptor⁻/⁻) knockout mice, showing no effect of conventional antidepressants, but effectiveness of NMDA antagonists.
Topics: Animals; Antidepressive Agents; Citalopram; Depression; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Imipramine; Ketamine; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Motor Activity; Psychological Tests; Reboxetine; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Swimming | 2015 |
The positive effect on ketamine as a priming adjuvant in antidepressant treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Depression; Depressive Disorder, Major; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Glutamic Acid; Imipramine; Ketamine; Male; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Wistar; Stress, Psychological | 2015 |
The effect of imipramine, ketamine, and zinc in the mouse model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Dexamethasone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Imipramine; Ketamine; Male; Mice; Motor Activity; Swimming; Synaptic Transmission; Zinc | 2015 |
Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a.
Topics: Animals; Carrier Proteins; Depression; Homer Scaffolding Proteins; Humans; Imipramine; Ketamine; Mice; Mice, Knockout; Mice, Transgenic; Prefrontal Cortex; Rats; Receptor, Adenosine A1; Signal Transduction; Sleep Deprivation | 2015 |
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Therapy; Corticosterone; Depressive Disorder; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activation; Fluoxetine; Imipramine; Insulin Resistance; Ketamine; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Conditioning, Animal; Prefrontal Cortex; Ribonucleotides; Triazenes | 2016 |
[Effects of ketamine, imipramine, and their combination on depression-like behaviors in Wistar Kyoto rats].
Topics: Animals; Brain; Depression; Depressive Disorder; Disease Models, Animal; Down-Regulation; Imipramine; Ketamine; Male; Rats; Rats, Inbred WKY; Swimming; Up-Regulation | 2016 |
Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles.
Topics: Amygdala; Animals; Brain; Depressive Disorder; Hippocampus; Imipramine; Ketamine; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Prefrontal Cortex; Resilience, Psychological; Sequence Analysis, RNA; Transcriptome | 2017 |
Exploring a post-traumatic stress disorder paradigm in Flinders sensitive line rats to model treatment-resistant depression II: response to antidepressant augmentation strategies.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cerebral Cortex; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Imipramine; Ketamine; Male; Rats; Rats, Transgenic; Stress Disorders, Post-Traumatic; Venlafaxine Hydrochloride | 2017 |
Antidepressant, anxiolytic and procognitive effects of subacute and chronic ketamine in the chronic mild stress model of depression.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Depression; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Imipramine; Ketamine; Male; Maze Learning; Nootropic Agents; Rats; Rats, Wistar; Stress, Psychological; Time Factors | 2017 |
Differential Mechanisms Underlying Antidepressant Responses of Ketamine and Imipramine.
Topics: Animals; Antidepressive Agents; CA1 Region, Hippocampal; Cyclic AMP Response Element-Binding Protein; Evoked Potentials; Imipramine; Ketamine; Male; Phosphorylation; Rats; Receptors, AMPA; Synaptic Transmission; Time Factors; Transcription Factors | 2017 |
Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease.
Topics: Anhedonia; Animals; Depression; Disease Models, Animal; Gait; Imipramine; Ketamine; Male; Nerve Degeneration; Oxidopamine; Parkinson Disease; Pars Compacta; Rats; Rats, Wistar; Substantia Nigra; Vocalization, Animal | 2018 |
Validation of chronic mild stress in the Wistar-Kyoto rat as an animal model of treatment-resistant depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Imipramine; Ketamine; Male; Prefrontal Cortex; Rats; Rats, Inbred WKY; Rats, Wistar; Stress, Psychological; Venlafaxine Hydrochloride | 2019 |
Toward Higher Sensitivity in Quantitative MALDI Imaging Mass Spectrometry of CNS Drugs Using a Nonpolar Matrix.
Topics: Animals; Brain Chemistry; Calibration; Central Nervous System Agents; Clonidine; Clozapine; Hydrophobic and Hydrophilic Interactions; Imipramine; Ketamine; Limit of Detection; Mice, Inbred C57BL; Nitriles; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xylazine | 2018 |
Esketamine and rapastinel, but not imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Imipramine; Ketamine; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Swimming; Treatment Outcome | 2019 |
mGluR5 mediates ketamine antidepressant response in susceptible rats exposed to prenatal stress.
Topics: Animals; Antidepressive Agents; Depression; Fluoxetine; Imipramine; Ketamine; Rats | 2020 |
Intermittent repeated stress but not ketamine changes mice response to antidepressants.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Fluoxetine; Imipramine; Ketamine; Male; Mice; Stress, Psychological | 2021 |
Ketamine reversed short-term memory impairment and depressive-like behavior in animal model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Imipramine; Ketamine; Male; Memory, Short-Term; Oxidopamine; Parkinson Disease; Pars Compacta; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2021 |
Proteome profile of telencephalon associates attenuated neurogenesis with chronic stress induced mood disorder phenotypes in zebrafish model.
Topics: Affect; Animals; Antidepressive Agents; Anxiety; Cell Proliferation; Depression; Disease Models, Animal; Female; Imipramine; Ketamine; Male; Mood Disorders; Neurogenesis; Phenotype; Proteome; Stress, Psychological; Telencephalon; Zebrafish | 2021 |