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ici 164384 and tamoxifen

ici 164384 has been researched along with tamoxifen in 122 studies

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-199014 (11.48)18.7374
1990's97 (79.51)18.2507
2000's9 (7.38)29.6817
2010's2 (1.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dufour, JM; Labrie, C; Labrie, F; Levesque, C; Merand, Y1
Bélanger, A; Caron, B; Cloutier, J; Dory, YL; Favre, A; Gauthier, S; Labrie, C; Labrie, F; Larouche, D; Leblanc, G; Mailhot, J; Martel, C; Mérand, Y; Ouellet, C; Schwerdtfeger, A; Simard, J1
Jain, D; Koh, JT1
Chang, C; Jiang, SY; Jordan, VC; Wolf, DM; Yingling, JM1
Jiang, SY; Jordan, VC1
Wakeling, AE4
Beug, H; Boehmelt, G; Enrietto, PJ; Kabrun, N; Mellitzer, G; Walker, A; Zenke, M1
Frenkel, K; Lim, JS; Troll, W1
Kangas, L1
Albaladejo, V; Andre, J; Joly-Pharaboz, MO; Nicolas, B; Zhou-Li, F1
Ballejo, G; Gong, Y; Murphy, LC; Murphy, LJ1
Emmas, CE; Fawell, SE; Hoare, SA; Parker, MG1
Lykkesfeldt, AE; Sørensen, EK1
Abbondanza, C; Armetta, I; Medici, N; Minucci, S; Molinari, AM; Moncharmont, B; Nigro, V; Puca, GA1
Katzenellenbogen, BS; Reese, JC1
Arbuckle, N; Danielian, P; Fawell, SE; Parker, MG1
Bowler, J; Wakeling, AE4
Michna, H; Nishino, Y; Schneider, MR; von Angerer, E1
Croxtall, JD; Jamil, A; White, JO1
Giambiagi, N; Pasqualini, JR1
Gottardis, MM; Jordan, VC; Satyaswaroop, PG1
Nguyen, BL; Pasqualini, JR1
Chetrite, G; Pasqualini, JR1
Berry, M; Chambon, P; Metzger, D1
Bouzubar, N; Davies, P; Gee, JM; Nicholson, RI; Rushmere, NK; Walker, KJ; Wills, RJ1
Baxter, JD; Greene, GL; Hort, E; Kushner, PJ; Shine, J1
Jordan, VC; Murphy, CS; Pink, JJ1
Gottardis, MM; Jordan, VC; Ricchio, ME; Satyaswaroop, PG1
Gelly, C; Nguyen, BL; Pasqualini, JR1
Galman, MS; Lyttle, CR; Sundstrom, SA1
Dickson, RB; Katz, D; Lippman, ME; Shima, TB; Thompson, EW; Wakeling, AE1
Dufour, JM; Labrie, F; Levesque, C; Merand, Y; Poirier, D; Poulin, R1
Johnson, MD; Kastner, P; May, FE; Wakeling, AE; Westley, BR; Wiseman, LR1
Newboult, E; Peters, SW; Wakeling, AE1
Gottardis, MM; Jeng, MH; Jiang, SY; Jordan, VC1
Cormier, EM; Jordan, VC1
Giambiagi, N; Pasqualini, JR; Sumida, C1
Gelly, C; Pasqualini, JR1
Chambon, P; Green, S; Jin, JR; Webster, NJ1
Chambon, P; Endoh, H; Gotoh, Y; Kato, S; Kawashima, H; Kitamoto, T; Masuhiro, Y; Masushige, S; Metzger, D; Nishida, E; Sasaki, H; Uchiyama, S1
Dekker, A; Dorssers, LC; Foekens, JA; van Agthoven, T; van Agthoven, TL1
Chambon, P; Chiba, H; Clifford, J; Metzger, D1
Gee, JM; Katzenellenbogen, BS; Manning, DL; Montano, MM; Nicholson, RI; Wakeling, AE1
Bhardwaj, B; Fujimoto, N; Katzenellenbogen, BS; Kraus, WL; Le Goff, P; Montano, MM; Schodin, DJ1
Aliau, S; Borgna, JL; Groblewski, T1
Dickson, RB; Johnson, GR; Martínez-Lacaci, I; Normanno, N; Plowman, GD; Saceda, M; Salomon, DS1
Collins, DC; Gagliardi, A1
Dauvois, S; Mahfoudi, A; Parker, MG; Roulet, E; Wahli, W1
Briand, P; Larsen, SS; Lykkesfeldt, AE1
Auger, S; Labrie, F; Mérand, Y; Pelletier, JD; Poirier, D1
Fritsch, M; Jiang, SY; Jordan, VC; Pink, JJ1
Birkenhäger, JC; Kleinekoort, WM; Pols, HA; van den Bemd, GJ; van Leeuwen, JP; Vink-van Wijngaarden, T1
Halliwell, B; Wiseman, H1
King, RJ; Lewis, DF; Parker, MG1
Clairmont, A; Drewes, T; Klein-Hitpass, L; Ryffel, GU1
Cavaillès, V; Danielian, PS; Dauvois, S; Parker, MG1
Badia, E; Duchesne, MJ; Fournier-Bidoz, S; Nicolas, JC; Pons, M; Simar-Blanchet, AE; Terouanne, B1
Musgrove, EA; Sutherland, RL; Sweeney, KJ; Warlters, A; Watts, CK1
Biberger, C; Holler, E; Koop, R; Leichtl, S; von Angerer, E1
Miksicek, RJ1
Haase, S; Shapiro, DJ; Xing, H1
Aronica, SM; Katzenellenbogen, BS; Kraus, WL1
Crew, AJ; Langdon, SP; Miller, WR; Muir, M; Ritchie, AA; Smyth, JF; Wakeling, A1
Johnson, MD; Lykkesfeldt, AE; May, FE; Wakeling, AE; Westley, BR; Wiseman, LR1
Wiseman, H1
Dauvois, S; Parker, MG; White, R1
Briand, P; Lykkesfeldt, AE; Madsen, MW1
Bondy, KL; McDonell, P; Wu, ZF; Zacharewski, TR1
Bicknell, R; Harris, AL; Toi, M1
Allan, GF; Beekman, JM; O'Malley, BW; Tsai, MJ; Tsai, SY1
Brünner, N; Clarke, R; Coopman, P; Derocq, D; Garcia, M; Rochefort, H1
Chalbos, D; Philips, A; Rochefort, H1
Conneely, OM; O'Malley, BW; Smith, CL1
Chalbos, D; Galtier, F; Philips, A; Rochefort, H1
Chetrite, G; Pasqualini, JR; Urabe, M1
Santen, RJ; Santner, SJ1
Sager, R; Webster, L; Zajchowski, DA1
Ali, S; Bornert, JM; Chambon, P; Metzger, D1
Manning, DL; Nicholson, RI1
Adlercreutz, H; Garey, J; Gurpide, E; Markiewicz, L1
Furlow, JD; Gorski, J; Murdoch, FE1
Christianson, T; Clinton, GM; Hua, W; Rochefort, H; Rougeot, C1
Clerico, L; de Cupis, A; Favoni, RE; Ferrera, A; Noonan, D; Pirani, P1
Clemm, DL; Goldman, ME; Hermann, T; McDonnell, DP; Pike, JW1
Kudoh, M1
Sakamoto, H; Satoh, K; Shirakawa, T1
Bursch, W; Ellinger, A; Hermann, RS; Kienzl, H; Pandey, S; Sikorska, M; Török, L; Walker, R1
Ekena, K; Katzenellenbogen, BS; Keller, AL; Krueger, KD; Montano, MM1
Glasser, SR; Mulholland, J; Wang, G1
Fournier, B; Häring, S; Kaye, AM; Sömjen, D1
Barrett, JC; Taguchi, S; Tanaka, Y; Tsutsui, T1
Flouriot, G; Pakdel, F; Valotaire, Y1
Briand, P; Larsen, SS; Lykkesfeldt, AE; Madsen, MW; Reiter, BE1
Gurpide, E; Markiewicz, L1
Eng, FC; Ferrara, J; Lee, HS; White, JH; Willson, TM1
Gustafsson, J; Kuiper, GG; Kushner, PJ; Nilsson, S; Paech, K; Scanlan, TS; Webb, P1
Bonnet, S; Brouillet, JP; Derocq, D; Garcia, M; Platet, N; Rochefort, H; Touitou, I1
Bartholdi, M; Humm, R; Simmons, SJ; Webster, L; White, FA; Zajchowski, DA1
Anghel, SI; Barsalou, A; Carrière, J; Gao, W; Mader, S1
Barkhem, T; Carlsson, B; Enmark, E; Gustafsson, J; Nilsson, S; Nilsson, Y1
Musgrove, EA; Prall, OW; Sutherland, RL; Wilcken, NR1
El Khissiin, A; Laios, I; Larsimont, D; Leclercq, G; Legros, N; Querton, G; Seo, HS1
Kuiper, GG; Pols, HA; Van Den Bemd, GJ; Van Leeuwen, JP1
Jeannin, E; Liu, JW; Picard, D1
Egeblad, M; Jäättelä, M; Larsen, SS; Lykkesfeldt, AE1
Löwik, CW; Papapoulos, SE; van Bezooijen, RL; Van der Bent, C1
Aberle, S; Fritzemeier, KH; Hegele-Hartung, C; Humm, R; Kauser, K; Knauthe, R; Liu, HL; MacRobbie, J; Ponte, P; Rubanyi, GM; Vergona, R; Webster, L; White, FA; Zajchowski, DA; Zhu, D1
Cenni, B; Delafontaine, P; Picard, D; Scheidegger, KJ1
Katzenellenbogen, BS; van der Burg, B; van der Saag, PT; Wissink, S1
Baldi, E; Bonaccorsi, L; Forti, G; Luconi, M1
Flouriot, G; Métivier, R; Pakdel, F; Penot, G1
Lopes, P; Trémollières, F1
Brockdorff, BL; Heiberg, I; Lykkesfeldt, AE1
Espelund, U; Jepsen, JS; Juncker-Jensen, A; Lykkesfeldt, AE; Ralfkiaer, U; Worm, J1
Fichtner, I; Frogne, T; Issinger, OG; Lykkesfeldt, AE; Stenvang, J; Yde, CW1
Berns, EM; Foekens, JA; Jansen, MP; Look, MP; Reijm, EA; Ruigrok-Ritstier, K; Sieuwerts, AM; Sleijfer, S; van Gelder, ME; van Staveren, IL1

Reviews

9 review(s) available for ici 164384 and tamoxifen

ArticleYear
A molecular strategy to control tamoxifen resistant breast cancer.
    Cancer surveys, 1992, Volume: 14

    Topics: Breast Neoplasms; Cell Division; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Humans; Models, Biological; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Transfection

1992
Steroid antagonists as nuclear receptor blockers.
    Cancer surveys, 1992, Volume: 14

    Topics: Androgen Antagonists; Anilides; Animals; Estradiol; Estrogen Antagonists; Estrogens; Humans; Mifepristone; Nitriles; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Tamoxifen; Tosyl Compounds

1992
Agonistic and antagonistic effects of antiestrogens in different target organs.
    Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:2

    Topics: Animals; Bone and Bones; Breast Neoplasms; Estradiol; Female; Gene Expression Regulation, Neoplastic; Liver; Mice; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Tamoxifen; Toremifene; Uterus

1992
Development of novel oestrogen-receptor antagonists.
    Biochemical Society transactions, 1991, Volume: 19, Issue:4

    Topics: Animals; Breast Neoplasms; Drug Design; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen

1991
Pharmacodynamic and biological effects of anti-estrogens in different models.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:4B

    Topics: Animals; Antibodies, Monoclonal; Cell Division; Clomiphene; DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Female; Growth Substances; Humans; Lipoproteins, LDL; Liver; Nafoxidine; Nitromifene; Polyunsaturated Alkamides; Pyrrolidines; Receptors, Estrogen; Receptors, Progesterone; Species Specificity; Structure-Activity Relationship; Tamoxifen; Thiophenes; Uterus

1988
Biology and mode of action of pure antioestrogens.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:12

    Topics: Animals; Estradiol; Estrogen Antagonists; Humans; Polyunsaturated Alkamides; Tamoxifen

1988
Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer.
    Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761

    Topics: Breast Neoplasms; Drug Resistance; Estradiol; Estradiol Congeners; Estrogen Antagonists; Female; Fulvestrant; Humans; In Vitro Techniques; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1995
[Strategy of drug development for hormone-dependent tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:6

    Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Humans; Male; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Prostatic Neoplasms; Tamoxifen

1996
[Specific estrogen receptor modulators (SERMs)].
    Presse medicale (Paris, France : 1983), 2002, Sep-07, Volume: 31, Issue:28

    Topics: Adult; Antineoplastic Agents, Hormonal; Bone and Bones; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Endometrium; Estradiol; Estrogen Antagonists; Estrogen Replacement Therapy; Female; Humans; Lipid Metabolism; Menopause; Middle Aged; Osteoporosis, Postmenopausal; Placebos; Polyunsaturated Alkamides; Postmenopause; Prospective Studies; Quality of Life; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors

2002

Other Studies

113 other study(ies) available for ici 164384 and tamoxifen

ArticleYear
Synthesis and biological activity of new halo-steroidal antiestrogens.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Estradiol; Estrogen Antagonists; Female; Mice; Mice, Inbred BALB C; Structure-Activity Relationship; Uterus

1991
(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen.
    Journal of medicinal chemistry, 1997, Jul-04, Volume: 40, Issue:14

    Topics: Administration, Oral; Animals; Benzopyrans; Binding, Competitive; Breast Neoplasms; Cytosol; Diethylstilbestrol; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Molecular Structure; Ovariectomy; Piperidines; Propionates; Raloxifene Hydrochloride; Receptors, Estrogen; Stereoisomerism; Structure-Activity Relationship; Uterus

1997
A mutant selective anti-estrogen is a pure antagonist on EREs and AP-1 response elements.
    Bioorganic & medicinal chemistry letters, 2010, Sep-01, Volume: 20, Issue:17

    Topics: Estrogen Receptor Modulators; Mutation; Receptors, Estrogen; Transcription Factor AP-1

2010
An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol.
    Molecular and cellular endocrinology, 1992, Volume: 90, Issue:1

    Topics: Breast Neoplasms; Cell Division; Clone Cells; DNA, Neoplasm; Drug Resistance; ErbB Receptors; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polymerase Chain Reaction; Polyunsaturated Alkamides; Progesterone; Receptors, Estrogen; Recombinant Fusion Proteins; Signal Transduction; Tamoxifen; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured

1992
Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression.
    The EMBO journal, 1992, Volume: 11, Issue:12

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Cells, Cultured; Chickens; Culture Techniques; DNA, Single-Stranded; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression Regulation; Humans; Molecular Sequence Data; NF-kappa B; Oncogene Proteins v-rel; Polyunsaturated Alkamides; Protein-Tyrosine Kinases; Receptors, Estrogen; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; RNA, Messenger; Tamoxifen; Transcription, Genetic

1992
Tamoxifen suppresses tumor promoter-induced hydrogen peroxide formation by human neutrophils.
    Cancer research, 1992, Sep-15, Volume: 52, Issue:18

    Topics: Estradiol; Estrogen Antagonists; Humans; Hydrogen Peroxide; Neutrophils; Polyunsaturated Alkamides; Tamoxifen; Tetradecanoylphorbol Acetate

1992
Antiestrogens prevent the stimulatory effects of L-triiodothyronine on cell proliferation.
    Endocrinology, 1992, Volume: 130, Issue:3

    Topics: Breast Neoplasms; Cell Division; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; Humans; Insulin-Like Growth Factor I; Pituitary Neoplasms; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Thyroid Hormone; RNA, Messenger; Tamoxifen; Transcription, Genetic; Triiodothyronine; Tumor Cells, Cultured

1992
Differential effects of estrogen and antiestrogen on transforming growth factor gene expression in endometrial adenocarcinoma cells.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7

    Topics: Adenocarcinoma; Analysis of Variance; Cell Division; Cell Line; Dose-Response Relationship, Drug; Endometrial Neoplasms; ErbB Receptors; Estradiol; Estrogen Antagonists; Female; Gene Expression; Humans; Kinetics; Polyunsaturated Alkamides; Pyrrolidines; RNA, Messenger; Tamoxifen; Thiophenes; Transforming Growth Factor alpha; Tumor Cells, Cultured

1992
Effect of ligand binding and DNA binding on the structure of the mouse oestrogen receptor.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 41, Issue:3-8

    Topics: Animals; Baculoviridae; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; DNA-Binding Proteins; Endopeptidases; Estradiol; Estrogen Antagonists; Kinetics; Ligands; Mice; Molecular Sequence Data; Peptide Mapping; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Tamoxifen; Transfection

1992
Effect of estrogen and antiestrogens on cell proliferation and synthesis of secreted proteins in the human breast cancer cell line MCF-7 and a tamoxifen resistant variant subline, AL-1.
    Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:2

    Topics: Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Drug Resistance; Estradiol; Estrogen Antagonists; Female; Humans; Molecular Weight; Neoplasm Proteins; Polyunsaturated Alkamides; Tamoxifen; Tumor Cells, Cultured

1992
Proteolytic activity of the purified hormone-binding subunit in the estrogen receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, May-15, Volume: 88, Issue:10

    Topics: Amino Acid Sequence; Animals; Aprotinin; Cattle; Chromogenic Compounds; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Estradiol; Estrogen Antagonists; Female; Hydrolysis; Isoflurophate; Molecular Sequence Data; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Uterus

1991
Differential DNA-binding abilities of estrogen receptor occupied with two classes of antiestrogens: studies using human estrogen receptor overexpressed in mammalian cells.
    Nucleic acids research, 1991, Dec-11, Volume: 19, Issue:23

    Topics: Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; DNA; Estradiol; Estrogen Antagonists; Gene Expression; Humans; Molecular Sequence Data; Polyunsaturated Alkamides; Promoter Regions, Genetic; Protein Binding; Receptors, Estrogen; Tamoxifen; Transfection

1991
Role of ligand in oestrogen-receptor function.
    Biochemical Society transactions, 1991, Volume: 19, Issue:4

    Topics: Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Humans; Ligands; Molecular Structure; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen

1991
Pharmacological characterization of a novel oestrogen antagonist, ZK 119010, in rats and mice.
    The Journal of endocrinology, 1991, Volume: 130, Issue:3

    Topics: Animals; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Female; Mice; Mice, Inbred Strains; Organ Size; Ovariectomy; Polyunsaturated Alkamides; Rats; Rats, Inbred Strains; Specific Pathogen-Free Organisms; Tamoxifen; Uterus; Vagina

1991
The effect of anti-oestrogens on cell growth and progesterone receptor concentration in human endometrial cancer cells (Ishikawa).
    Journal of molecular endocrinology, 1991, Volume: 6, Issue:3

    Topics: Cell Division; Estradiol; Estrogen Antagonists; Female; Humans; Polyunsaturated Alkamides; Receptors, Progesterone; Tamoxifen; Tumor Cells, Cultured; Uterine Neoplasms

1991
Studies on the activation of the oestrogen receptor bound to the anti-oestrogens 4-hydroxytamoxifen and ICI 164,384 by using three monoclonal antibodies.
    Journal of molecular endocrinology, 1991, Volume: 7, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Binding Sites; DNA; Estradiol; Estrogen Antagonists; Female; Guinea Pigs; Polyunsaturated Alkamides; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Temperature; Uterus

1991
Tamoxifen-stimulated growth of human endometrial carcinoma.
    Annals of the New York Academy of Sciences, 1991, Volume: 622

    Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Clomiphene; Enclomiphene; Endometrium; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Mice, Inbred BALB C; Nafoxidine; Neoplasm Transplantation; Piperidines; Polyunsaturated Alkamides; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Uterine Neoplasms

1991
Estrone sulfatase activity and effect of antiestrogens on transformation of estrone sulfate in hormone-dependent vs. independent human breast cancer cell lines.
    Breast cancer research and treatment, 1991, Volume: 18, Issue:2

    Topics: Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Sulfatases; Tamoxifen; Tumor Cells, Cultured

1991
Biological responses of ICI 164,384 and other anti-estrogens in vaginal and uterine cells of fetal guinea pig in culture.
    Acta endocrinologica, 1991, Volume: 125, Issue:4

    Topics: Animals; Cell Division; Cell Separation; Cells, Cultured; DNA; Estradiol; Estrogen Antagonists; Female; Fetus; Guinea Pigs; Polyunsaturated Alkamides; Receptors, Progesterone; Tamoxifen; Uterus; Vagina

1991
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.
    The EMBO journal, 1990, Volume: 9, Issue:9

    Topics: Animals; beta-Galactosidase; Chick Embryo; Chloramphenicol O-Acetyltransferase; Estradiol; Estrogen Antagonists; Fibroblasts; HeLa Cells; Humans; Polyunsaturated Alkamides; Promoter Regions, Genetic; Receptors, Estrogen; Saccharomyces cerevisiae; Tamoxifen; Transcription, Genetic; Transfection

1990
Estrogen deprivation in breast cancer. Clinical, experimental, and biological aspects.
    Annals of the New York Academy of Sciences, 1990, Volume: 595

    Topics: Breast Neoplasms; Buserelin; Estradiol; Estrogen Antagonists; Female; Gonadotropin-Releasing Hormone; Goserelin; Humans; Menopause; Polyunsaturated Alkamides; Tamoxifen

1990
Construction of cell lines that express high levels of the human estrogen receptor and are killed by estrogens.
    Molecular endocrinology (Baltimore, Md.), 1990, Volume: 4, Issue:10

    Topics: Animals; Cadmium; Cell Line; Cell Survival; Cricetinae; Drug Resistance; Enhancer Elements, Genetic; Estradiol; Estrogens; Female; Gene Amplification; Gene Expression; Metallothionein; Ovary; Polyunsaturated Alkamides; Promoter Regions, Genetic; Receptors, Estrogen; Simian virus 40; Tamoxifen; Transfection

1990
Characterization of a receptor-negative, hormone-nonresponsive clone derived from a T47D human breast cancer cell line kept under estrogen-free conditions.
    Cancer research, 1990, Nov-15, Volume: 50, Issue:22

    Topics: Blotting, Northern; Breast Neoplasms; Cell Division; Clone Cells; Cytidine; DNA Fingerprinting; DNA, Neoplasm; ErbB Receptors; Estradiol; Gene Expression; Humans; In Vitro Techniques; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Cells, Cultured

1990
Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimulated human endometrial carcinoma (EnCa101) in athymic mice.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Animals; Carcinoma; Cell Division; Delayed-Action Preparations; Estradiol; Estrogen Antagonists; Ethamoxytriphetol; Ethanol; Female; Mice; Mice, Inbred BALB C; Mice, Nude; Ovariectomy; Polyunsaturated Alkamides; Tamoxifen; Tumor Cells, Cultured; Uterine Neoplasms

1990
Metabolism and biologic response of estrogen sulfates in hormone-dependent and hormone-independent mammary cancer cell lines. Effect of antiestrogens.
    Annals of the New York Academy of Sciences, 1990, Volume: 595

    Topics: Breast Neoplasms; Estradiol; Estriol; Estrone; Female; Humans; Menstruation; Polyunsaturated Alkamides; Progesterone; Receptors, Progesterone; Tamoxifen; Tumor Cells, Cultured

1990
Novel pure antiestrogens. Mode of action and therapeutic prospects.
    Annals of the New York Academy of Sciences, 1990, Volume: 595

    Topics: Animals; Animals, Newborn; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Polyunsaturated Alkamides; Rats; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured; Uterus

1990
Antagonism of estrogen- and antiestrogen-induced uterine complement component C3 expression by ICI 164,384.
    Journal of steroid biochemistry, 1990, Jul-04, Volume: 36, Issue:4

    Topics: Animals; Complement C3; Epithelial Cells; Estradiol; Estrogen Antagonists; Female; Organ Size; Polyunsaturated Alkamides; Pyrrolidines; Rats; Rats, Inbred Strains; RNA, Messenger; Tamoxifen; Thiophenes; Uterus

1990
ICI 164,384, a pure antagonist of estrogen-stimulated MCF-7 cell proliferation and invasiveness.
    Cancer research, 1989, Dec-15, Volume: 49, Issue:24 Pt 1

    Topics: Basement Membrane; Binding, Competitive; Breast Neoplasms; Cell Cycle; Estradiol; Estrogen Antagonists; Humans; Neoplasm Invasiveness; Polyunsaturated Alkamides; Pyrrolidines; Receptors, Estrogen; Stimulation, Chemical; Tamoxifen; Thiophenes; Tumor Cells, Cultured

1989
Antiestrogenic properties of keoxifene, trans-4-hydroxytamoxifen, and ICI 164384, a new steroidal antiestrogen, in ZR-75-1 human breast cancer cells.
    Breast cancer research and treatment, 1989, Volume: 14, Issue:1

    Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Humans; Piperidines; Polyunsaturated Alkamides; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Time Factors; Tumor Cells, Cultured

1989
The potential for a novel pure anti-oestrogen.
    Hormone research, 1989, Volume: 32 Suppl 1

    Topics: Animals; Breast Neoplasms; Cell Line; Estradiol; Estrogen Antagonists; Female; Humans; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Tamoxifen; Uterus

1989
Regulation of progesterone receptor mRNA by oestradiol and antioestrogens in breast cancer cell lines.
    Journal of steroid biochemistry, 1989, Volume: 33, Issue:6

    Topics: Animals; Autoradiography; Blotting, Northern; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogen Antagonists; Mammary Neoplasms, Experimental; Polyunsaturated Alkamides; Pyrrolidines; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Thiophenes; Tumor Cells, Cultured

1989
Effects of antioestrogens on the proliferation of MCF-7 human breast cancer cells.
    Journal of molecular endocrinology, 1989, Volume: 2, Issue:3

    Topics: Breast Neoplasms; Cell Division; Depression, Chemical; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Humans; Insulin; Insulin-Like Growth Factor I; Polyunsaturated Alkamides; Tamoxifen; Transforming Growth Factors; Tumor Cells, Cultured

1989
Comparative studies on the effects of steroidal and nonsteroidal oestrogen antagonists on the proliferation of human breast cancer cells.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: Breast Neoplasms; Cell Division; Cell Line; Estradiol; Estrogen Antagonists; Female; Humans; Insulin; Kinetics; Polyunsaturated Alkamides; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured

1989
Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens.
    Cancer research, 1989, Aug-01, Volume: 49, Issue:15

    Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Polyunsaturated Alkamides; Tamoxifen; Transplantation, Heterologous

1989
Contrasting ability of antiestrogens to inhibit MCF-7 growth stimulated by estradiol or epidermal growth factor.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:1

    Topics: Breast Neoplasms; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Female; Humans; Mitosis; Polyunsaturated Alkamides; Tamoxifen; Time Factors

1989
[Cancer of the breast, mechanism of action of anti-estrogens].
    Pathologie-biologie, 1988, Volume: 36, Issue:8

    Topics: Breast Neoplasms; Cell Line, Transformed; Estradiol; Estrone; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Tamoxifen

1988
The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function.
    Cell, 1988, Jul-15, Volume: 54, Issue:2

    Topics: DNA; Estradiol; Estrenes; Estrogen Antagonists; Estrogens; Glucocorticoids; HeLa Cells; Hormones; Humans; Mifepristone; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Glucocorticoid; Tamoxifen; Transcription Factors; Transcription, Genetic; Transfection

1988
Steroidal pure antioestrogens.
    The Journal of endocrinology, 1987, Volume: 112, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Mice; Polyunsaturated Alkamides; Rats; Tamoxifen; Uterus

1987
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase.
    Science (New York, N.Y.), 1995, Dec-01, Volume: 270, Issue:5241

    Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Humans; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutation; Phosphorylation; Polyunsaturated Alkamides; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Receptors, Estrogen; Recombinant Fusion Proteins; Serine; Somatomedins; Tamoxifen; Transcriptional Activation; Transfection

1995
Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterations.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:11

    Topics: Azacitidine; Breast Neoplasms; Down-Regulation; ErbB Receptors; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Keratins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proteins; Receptor, ErbB-2; Receptors, Estradiol; Receptors, Progesterone; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

1994
Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jul-18, Volume: 92, Issue:15

    Topics: DNA Nucleotidyltransferases; Enzyme Induction; Estradiol; Estrogen Antagonists; Gene Targeting; Genetic Vectors; Integrases; Mutagenesis, Site-Directed; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Tamoxifen; Tumor Cells, Cultured; Viral Proteins

1995
Antiestrogens: mechanisms and actions in target cells.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 53, Issue:1-6

    Topics: Cyclic AMP; Estradiol; Estrogen Antagonists; Gene Expression Regulation; Humans; In Vitro Techniques; Ligands; Phosphorylation; Polyunsaturated Alkamides; Promoter Regions, Genetic; Protein Kinases; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Tamoxifen; Transcriptional Activation

1995
The effect of free DNA on the interactions of the estrogen receptor bound to hormone, partial antagonist or pure antagonist with target DNA.
    European journal of biochemistry, 1995, Jul-01, Volume: 231, Issue:1

    Topics: Animals; Bacterial Proteins; Base Sequence; DNA; Estradiol; Estrogen Antagonists; Estrogens; Female; Molecular Sequence Data; Polyunsaturated Alkamides; Receptors, Estrogen; Sheep; Streptavidin; Tamoxifen

1995
Estrogen and phorbol esters regulate amphiregulin expression by two separate mechanisms in human breast cancer cell lines.
    Endocrinology, 1995, Volume: 136, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amphiregulin; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Bryostatins; Culture Media, Conditioned; Cycloheximide; Dose-Response Relationship, Drug; EGF Family of Proteins; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression Regulation, Neoplastic; Glycoproteins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Isoquinolines; Lactones; Macrolides; Piperazines; Polyunsaturated Alkamides; Protein Kinase C; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Inhibition of angiogenesis by antiestrogens.
    Cancer research, 1993, Feb-01, Volume: 53, Issue:3

    Topics: Animals; Chick Embryo; Clomiphene; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Fulvestrant; Heparin; Hydrocortisone; Nafoxidine; Neovascularization, Pathologic; Polyunsaturated Alkamides; Solubility; Tamoxifen

1993
Specific mutations in the estrogen receptor change the properties of antiestrogens to full agonists.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, May-09, Volume: 92, Issue:10

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chickens; Conserved Sequence; DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Gene Expression; HeLa Cells; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oncorhynchus mykiss; Point Mutation; Polyunsaturated Alkamides; Protein Structure, Secondary; Rats; Receptors, Estrogen; Recombinant Proteins; Sequence Homology, Amino Acid; Tamoxifen; Transcription, Genetic; Transfection; Xenopus

1995
Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatment.
    International journal of cancer, 1995, May-16, Volume: 61, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Tumor Cells, Cultured

1995
Synthesis and biological activities of thioether derivatives related to the antiestrogens tamoxifen and ICI 164384.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:6

    Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Humans; In Vitro Techniques; Molecular Structure; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured

1995
An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein.
    Cancer research, 1995, Jun-15, Volume: 55, Issue:12

    Topics: Blotting, Western; Breast Neoplasms; Cell Division; Clone Cells; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Luciferases; Molecular Weight; Polyunsaturated Alkamides; Protein Biosynthesis; Proteins; Receptors, Estrogen; Receptors, Progesterone; Recombinant Proteins; Tamoxifen; Time Factors; Transfection; Tumor Cells, Cultured; Up-Regulation

1995
Antiestrogens inhibit in vitro bone resorption stimulated by 1,25-dihydroxyvitamin D3 and the vitamin D3 analogs EB1089 and KH1060.
    Endocrinology, 1995, Volume: 136, Issue:2

    Topics: Animals; Bone Resorption; Calcitriol; Dose-Response Relationship, Drug; Estradiol; Mice; Polyunsaturated Alkamides; Tamoxifen

1995
Tamoxifen and related compounds protect against lipid peroxidation in isolated nuclei: relevance to the potential anticarcinogenic benefits of breast cancer prevention and therapy with tamoxifen?
    Free radical biology & medicine, 1994, Volume: 17, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Nucleus; Estradiol; Estrogen Antagonists; Female; Humans; Lipid Peroxidation; Liver; Male; Nafoxidine; Polyunsaturated Alkamides; Rats; Rats, Wistar; Structure-Activity Relationship; Tamoxifen

1994
Molecular modelling of the human estrogen receptor and ligand interactions based on site-directed mutagenesis and amino acid sequence homology.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:1

    Topics: Computer Simulation; Estradiol; Estrogen Antagonists; Humans; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Polyunsaturated Alkamides; Protein Conformation; Receptors, Estrogen; Tamoxifen

1995
Estrogen-inducible derivatives of hepatocyte nuclear factor-4, hepatocyte nuclear factor-3 and liver factor B1 are differently affected by pure and partial antiestrogens.
    European journal of biochemistry, 1994, Oct-01, Volume: 225, Issue:1

    Topics: Animals; Base Sequence; Cell Line; Diethylstilbestrol; DNA Primers; DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Hepatocyte Nuclear Factor 3-alpha; Hepatocyte Nuclear Factor 3-beta; Hepatocyte Nuclear Factor 3-gamma; Hepatocyte Nuclear Factor 4; Kinetics; Liver; Liver Neoplasms, Experimental; Molecular Sequence Data; Nuclear Proteins; Phosphoproteins; Polymerase Chain Reaction; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Substrate Specificity; Tamoxifen; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured

1994
Interaction of proteins with transcriptionally active estrogen receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21

    Topics: Animals; Base Sequence; Blotting, Western; Cell Line; Cell Nucleus; Cell-Free System; Chlorocebus aethiops; DNA Primers; DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Fulvestrant; Glutathione Transferase; HeLa Cells; Humans; Kidney; Molecular Sequence Data; Nuclear Proteins; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Fusion Proteins; Tamoxifen; Transcription, Genetic

1994
Hydroxytamoxifen induces a rapid and irreversible inactivation of an estrogenic response in an MCF-7-derived cell line.
    Cancer research, 1994, Nov-15, Volume: 54, Issue:22

    Topics: Base Sequence; Breast Neoplasms; Cell Division; Cell Line; Enzyme Induction; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Enzymologic; Humans; Luciferases; Molecular Sequence Data; Plasmids; Polyunsaturated Alkamides; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Transfection; Tumor Cells, Cultured

1994
Antiestrogen regulation of cell cycle progression and cyclin D1 gene expression in MCF-7 human breast cancer cells.
    Breast cancer research and treatment, 1994, Volume: 31, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Culture Media, Serum-Free; Cyclin D1; Cyclins; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Mice; Mice, Nude; Oncogene Proteins; Polyunsaturated Alkamides; Tamoxifen; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured

1994
1-Carbamoylalkyl-2-phenylindoles: relationship between side chain structure and estrogen antagonism.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; HeLa Cells; Humans; Indoles; Mice; Organ Size; Polyunsaturated Alkamides; Radioligand Assay; Receptors, Estrogen; Sequence Deletion; Structure-Activity Relationship; Tamoxifen; Transcriptional Activation; Tumor Cells, Cultured; Uterus

1994
Interaction of naturally occurring nonsteroidal estrogens with expressed recombinant human estrogen receptor.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:2-3

    Topics: Binding, Competitive; Estradiol; Estrogens, Non-Steroidal; Fungi; HeLa Cells; Humans; Plants; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Proteins; Tamoxifen; Transcription, Genetic; Transfection

1994
Antiestrogens activate an estrogen receptor mutant exhibiting enhanced binding to the estrogen response element.
    Biochemical and biophysical research communications, 1994, Jul-29, Volume: 202, Issue:2

    Topics: Animals; Cell Line; DNA; Drug Resistance; Estradiol; Estrogen Antagonists; HeLa Cells; Humans; Liver; Mutation; Polyunsaturated Alkamides; Promoter Regions, Genetic; Receptors, Estrogen; Tamoxifen; Transcription, Genetic; Transfection; Xenopus

1994
Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-30, Volume: 91, Issue:18

    Topics: Adenylyl Cyclases; Animals; Base Sequence; Breast Neoplasms; Cells, Cultured; Cyclic AMP; Estradiol; Female; Gene Expression Regulation; Humans; In Vitro Techniques; Molecular Sequence Data; Oligodeoxyribonucleotides; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Signal Transduction; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured; Uterus

1994
Growth inhibition of oestrogen receptor-positive human ovarian carcinoma by anti-oestrogens in vitro and in a xenograft model.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:5

    Topics: Adenocarcinoma; Animals; Cell Division; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Transplantation, Heterologous; Tumor Cells, Cultured

1994
Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:16

    Topics: Breast Neoplasms; Cell Adhesion; Cell Division; Dose-Response Relationship, Drug; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Insulin-Like Growth Factor I; Polyunsaturated Alkamides; Receptor, IGF Type 1; Tamoxifen; Tumor Cells, Cultured

1993
The antioxidant action of a pure antioestrogen: ability to inhibit lipid peroxidation compared to tamoxifen and 17 beta-oestradiol and relevance to its anticancer potential.
    Biochemical pharmacology, 1994, Feb-09, Volume: 47, Issue:3

    Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Brain; Cattle; Estradiol; Ferric Compounds; Lipid Peroxidation; Male; Microsomes, Liver; Nafoxidine; Polyunsaturated Alkamides; Rats; Tamoxifen

1994
The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling.
    Journal of cell science, 1993, Volume: 106 ( Pt 4)

    Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Compartmentation; Cell Nucleus; Cells, Cultured; Chlorocebus aethiops; Cytoplasm; Estradiol; Estrogen Antagonists; Fulvestrant; Hybrid Cells; Mice; Molecular Sequence Data; Oligomycins; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Proteins; Sequence Homology, Amino Acid; Tamoxifen; Transfection

1993
Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-1.
    Cancer research, 1994, Mar-15, Volume: 54, Issue:6

    Topics: Animals; Base Sequence; Breast Neoplasms; Cell Division; Chloramphenicol O-Acetyltransferase; Culture Media; Drug Resistance; Drug Screening Assays, Antitumor; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Time Factors; Transfection; Tumor Cells, Cultured

1994
Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17 beta-estradiol-induced pS2 expression.
    Cancer research, 1994, May-15, Volume: 54, Issue:10

    Topics: Base Sequence; Breast Neoplasms; Dioxins; Estradiol; Firefly Luciferin; Genes, Reporter; HeLa Cells; Humans; Molecular Sequence Data; Neoplasm Proteins; Polychlorinated Dibenzodioxins; Polyunsaturated Alkamides; Proteins; Receptors, Aryl Hydrocarbon; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

1994
cDNA transfection followed by the isolation of a MCF-7 breast cell line resistant to tamoxifen in vitro and in vivo.
    British journal of cancer, 1993, Volume: 68, Issue:6

    Topics: Animals; Breast Neoplasms; Cloning, Molecular; Culture Media, Conditioned; DNA, Complementary; DNA, Neoplasm; DNA, Recombinant; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Female; Growth Substances; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain.
    Molecular endocrinology (Baltimore, Md.), 1993, Volume: 7, Issue:10

    Topics: Animals; Baculoviridae; Base Sequence; Binding Sites; Chymotrypsin; Cold Temperature; DNA; Estradiol; Estrogens; Gene Expression Regulation; Humans; Molecular Sequence Data; Moths; Nafoxidine; Polyunsaturated Alkamides; Protein Conformation; Receptors, Estrogen; Recombinant Proteins; Sodium Fluoride; Tamoxifen; Transcription, Genetic; Transcriptional Activation; Transfection

1993
Anti-proliferative and anti-estrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast-cancer cells.
    International journal of cancer, 1994, Jan-15, Volume: 56, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cathepsin D; Cell Division; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proteins; Receptors, Estrogen; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

1994
Estradiol increases and anti-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis.
    The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19

    Topics: Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Female; Genes, fos; Genes, jun; Humans; Insulin-Like Growth Factor I; Kinetics; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Estrogen; Recombinant Fusion Proteins; RNA, Messenger; Tamoxifen; Thymidine Kinase; Time Factors; Transfection; Tumor Cells, Cultured

1993
Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jul-01, Volume: 90, Issue:13

    Topics: Chloramphenicol O-Acetyltransferase; Dopamine; Estradiol; Estrogen Antagonists; Estrogens; HeLa Cells; Humans; Ligands; Polyunsaturated Alkamides; Receptors, Dopamine; Receptors, Estrogen; Tamoxifen

1993
Synthetic antiestrogens modulate induction of pS2 and cathepsin-D messenger ribonucleic acid by growth factors and adenosine 3',5'-monophosphate in MCF7 cells.
    Endocrinology, 1993, Volume: 133, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Cathepsin D; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Growth Substances; Humans; Insulin-Like Growth Factor I; Neoplasm Proteins; Polyunsaturated Alkamides; Proteins; RNA, Messenger; Tamoxifen; Tetradecanoylphorbol Acetate; Transcription, Genetic; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

1993
Transformation of estrone, estradiol, and estrone sulfate in uterine and vaginal isolated cells of fetal guinea pig. Effect of various antiestrogens in the conversion of estrone sulfate to estradiol.
    Steroids, 1993, Volume: 58, Issue:5

    Topics: Animals; Cells, Cultured; Culture Media; DNA; Estradiol; Estrogen Antagonists; Estrone; Female; Guinea Pigs; Polyunsaturated Alkamides; Pregnancy; Tamoxifen; Uterus; Vagina

1993
Inhibition of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase by antiestrogens.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:5

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding, Competitive; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Polyunsaturated Alkamides; Pregnenolone; Rats; Rats, Sprague-Dawley; Sulfatases; Tamoxifen

1993
Estrogen inhibits the growth of estrogen receptor-negative, but not estrogen receptor-positive, human mammary epithelial cells expressing a recombinant estrogen receptor.
    Cancer research, 1993, Oct-15, Volume: 53, Issue:20

    Topics: Animals; Breast; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Mice; Mice, Nude; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Proteins; Tamoxifen; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured

1993
Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.
    The EMBO journal, 1993, Volume: 12, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Chloramphenicol O-Acetyltransferase; Estradiol; Estrogen Antagonists; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Polyunsaturated Alkamides; Receptors, Estrogen; Sequence Deletion; Serine; Tamoxifen; Transcription, Genetic

1993
Isolation of pMGT1: a gene that is repressed by oestrogen and increased by antioestrogens and antiprogestins.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:5

    Topics: Breast Neoplasms; DNA, Neoplasm; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Tumor Cells, Cultured

1993
In vitro bioassays of non-steroidal phytoestrogens.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:5

    Topics: Adenocarcinoma; Alkaline Phosphatase; Biological Assay; Chromans; Coumestrol; Dinoprost; Endometrial Neoplasms; Endometrium; Equol; Estradiol; Female; Genistein; Humans; Isoflavones; Polyunsaturated Alkamides; Tamoxifen; Tumor Cells, Cultured

1993
High affinity binding of the estrogen receptor to a DNA response element does not require homodimer formation or estrogen.
    The Journal of biological chemistry, 1993, Jun-15, Volume: 268, Issue:17

    Topics: Animals; Antibodies; Base Sequence; Cytosol; DNA; DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Female; Kinetics; Macromolecular Substances; Molecular Sequence Data; Oligodeoxyribonucleotides; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Restriction Mapping; Tamoxifen; Thermodynamics; Uterus

1993
SKOV3 ovarian carcinoma cells have functional estrogen receptor but are growth-resistant to estrogen and antiestrogens.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Cathepsin D; Cell Division; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Humans; Ovarian Neoplasms; Polyunsaturated Alkamides; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Tumor Cells, Cultured

1995
Comparison between novel steroid-like and conventional nonsteroidal antioestrogens in inhibiting oestradiol- and IGF-I-induced proliferation of human breast cancer-derived cells.
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Base Sequence; Blotting, Western; Breast Neoplasms; Cell Division; Culture Media, Conditioned; DNA; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Insulin-Like Growth Factor I; Molecular Sequence Data; Polyunsaturated Alkamides; RNA, Messenger; Steroids; Tamoxifen; Tumor Cells, Cultured

1995
Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.
    Molecular endocrinology (Baltimore, Md.), 1995, Volume: 9, Issue:6

    Topics: Animals; Cell Line; Chlorocebus aethiops; DNA; Estradiol; Estrogen Antagonists; Gene Expression Regulation; Kidney; Molecular Structure; Piperidines; Polyunsaturated Alkamides; Protein Binding; Protein Conformation; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Proteins; Structure-Activity Relationship; Tamoxifen; Transfection

1995
[Separation and characterization of estrogen independent endometrial cancer cell line originated from Ishikawa strain].
    Nihon Sanka Fujinka Gakkai zasshi, 1996, Volume: 48, Issue:2

    Topics: Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Tumor Cells, Cultured

1996
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy.
    Carcinogenesis, 1996, Volume: 17, Issue:8

    Topics: Autophagy; Breast Neoplasms; Cell Cycle; Cell Death; Estradiol; Estrogen Antagonists; Humans; L-Lactate Dehydrogenase; Polyunsaturated Alkamides; Tamoxifen; Trypan Blue; Tumor Cells, Cultured

1996
Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens.
    Molecular endocrinology (Baltimore, Md.), 1996, Volume: 10, Issue:3

    Topics: 3T3 Cells; Animals; Breast Neoplasms; CHO Cells; Cricetinae; Cricetulus; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Ligands; Mice; Neoplasms, Hormone-Dependent; Point Mutation; Polyunsaturated Alkamides; Promoter Regions, Genetic; Protein Binding; Receptors, Estrogen; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured

1996
Effects of tamoxifen and ICI 164384 on protein synthesis and vectorial secretion in polarized rat uterine epithelial cells.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:3

    Topics: Animals; Cell Polarity; Cells, Cultured; Dose-Response Relationship, Drug; Epithelium; Estradiol; Estrogen Antagonists; Female; Polyunsaturated Alkamides; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1996
Stimulation of creatine kinase specific activity in human osteoblast and endometrial cells by estrogens and anti-estrogens and its modulation by calciotropic hormones.
    The Journal of endocrinology, 1996, Volume: 150, Issue:2

    Topics: Calcitriol; Creatine Kinase; Endometrium; Estradiol; Estrogen Antagonists; Female; Humans; Osteoblasts; Piperidines; Plasmids; Polyunsaturated Alkamides; Raloxifene Hydrochloride; Recombinant Proteins; Stimulation, Chemical; Tamoxifen; Teriparatide; Tumor Cells, Cultured

1996
17beta-estradiol, diethylstilbestrol, tamoxifen, toremifene and ICI 164,384 induce morphological transformation and aneuploidy in cultured Syrian hamster embryo cells.
    International journal of cancer, 1997, Jan-17, Volume: 70, Issue:2

    Topics: Aneuploidy; Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Diethylstilbestrol; DNA; DNA Adducts; Embryo, Mammalian; Estradiol; Estrogen Antagonists; Mesocricetus; Molecular Structure; Polyunsaturated Alkamides; Structure-Activity Relationship; Tamoxifen; Toremifene

1997
Transcriptional and post-transcriptional regulation of rainbow trout estrogen receptor and vitellogenin gene expression.
    Molecular and cellular endocrinology, 1996, Nov-29, Volume: 124, Issue:1-2

    Topics: Animals; Cells, Cultured; Cycloheximide; Estradiol; Estrogen Antagonists; Gene Expression Regulation; Liver; Male; Oncorhynchus mykiss; Polyunsaturated Alkamides; Protein Synthesis Inhibitors; Receptors, Estrogen; RNA Processing, Post-Transcriptional; RNA, Messenger; Tamoxifen; Transcription, Genetic; Vitellogenins

1996
Estrogen receptor messenger RNA splice variants are not involved in antiestrogen resistance in sublines of MCF-7 human breast cancer cells.
    Cancer research, 1997, Feb-15, Volume: 57, Issue:4

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Genetic Vectors; Humans; Polyunsaturated Alkamides; Receptors, Estrogen; RNA Splicing; RNA, Messenger; RNA, Neoplasm; Tamoxifen; Transfection; Tumor Cells, Cultured

1997
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4

    Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured

1997
Probing the structure and function of the estrogen receptor ligand binding domain by analysis of mutants with altered transactivation characteristics.
    Molecular and cellular biology, 1997, Volume: 17, Issue:8

    Topics: Amino Acid Sequence; Animals; Cloning, Molecular; COS Cells; Estradiol; Estrogen Antagonists; Estrone; HSP90 Heat-Shock Proteins; Hydroxyestrones; Ligands; Molecular Sequence Data; Mutation; Nuclear Proteins; Polyunsaturated Alkamides; Receptors, Estrogen; Saccharomyces cerevisiae; Sequence Alignment; Tamoxifen; Transcriptional Activation

1997
Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites.
    Science (New York, N.Y.), 1997, Sep-05, Volume: 277, Issue:5331

    Topics: Animals; Breast Neoplasms; Cell Line; Diethylstilbestrol; Enhancer Elements, Genetic; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; HeLa Cells; Humans; Ligands; Piperidines; Polyunsaturated Alkamides; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Uterus

1997
Both estradiol and tamoxifen decrease proliferation and invasiveness of cancer cells transfected with a mutated estrogen receptor.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:1-2

    Topics: Animals; Cell Division; Estradiol; Estrogen Antagonists; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Invasiveness; Neoplasms, Experimental; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Tamoxifen; Transfection

1997
Different estrogen receptor structural domains are required for estrogen- and tamoxifen-dependent anti-proliferative activity in human mammary epithelial cells expressing an exogenous estrogen receptor.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 62, Issue:5-6

    Topics: Base Sequence; Binding Sites; Breast; Cell Division; Cell Line; DNA; DNA Primers; Epithelial Cells; Estradiol; Estrogen Antagonists; Female; Gene Expression; Humans; Mutation; Polymerase Chain Reaction; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Transfection

1997
Estrogen response elements can mediate agonist activity of anti-estrogens in human endometrial Ishikawa cells.
    The Journal of biological chemistry, 1998, Jul-03, Volume: 273, Issue:27

    Topics: Animals; Base Sequence; Cell Line; COS Cells; Electrophoresis, Polyacrylamide Gel; Endometrium; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation; Humans; Polyunsaturated Alkamides; Promoter Regions, Genetic; Receptors, Progesterone; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured

1998
Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists.
    Molecular pharmacology, 1998, Volume: 54, Issue:1

    Topics: Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Ligands; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen

1998
Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Polyunsaturated Alkamides; Proto-Oncogene Proteins; S Phase; Tamoxifen; Tumor Cells, Cultured; Zinc Sulfate

1997
Estrogenic and anti-estrogenic regulation of estrogen receptor in MCF-7 breast-cancer cells: comparison of immunocytochemical data with biochemical measurements.
    International journal of cancer, 1998, Dec-09, Volume: 78, Issue:6

    Topics: Breast Neoplasms; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Humans; Immunoenzyme Techniques; Immunohistochemistry; Kinetics; Okadaic Acid; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Time Factors; Tumor Cells, Cultured

1998
Distinct effects on the conformation of estrogen receptor alpha and beta by both the antiestrogens ICI 164,384 and ICI 182,780 leading to opposite effects on receptor stability.
    Biochemical and biophysical research communications, 1999, Jul-22, Volume: 261, Issue:1

    Topics: Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Humans; Ligands; Molecular Weight; Peptide Fragments; Polyunsaturated Alkamides; Protein Conformation; Receptors, Estrogen; Tamoxifen; Trypsin

1999
The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system.
    Biological chemistry, 1999, Volume: 380, Issue:11

    Topics: Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Humans; Indoles; Nafoxidine; Piperidines; Polyunsaturated Alkamides; Receptors, Estrogen; Saccharomyces cerevisiae; Sulfones; Tamoxifen; Two-Hybrid System Techniques

1999
Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family.
    Breast cancer research and treatment, 1999, Volume: 58, Issue:1

    Topics: Blotting, Northern; Blotting, Western; Breast Neoplasms; DNA Primers; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Polyunsaturated Alkamides; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Tamoxifen; Tumor Cells, Cultured

1999
Oestrogenic compounds modulate cytokine-induced nitric oxide production in mouse osteoblast-like cells.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:12

    Topics: Animals; Cells, Cultured; Cytokines; Estradiol; Estrogen Antagonists; Estrogens; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Mice; Nitric Oxide; Osteoblasts; Polyunsaturated Alkamides; Tamoxifen; Tumor Necrosis Factor-alpha

1999
Identification of selective estrogen receptor modulators by their gene expression fingerprints.
    The Journal of biological chemistry, 2000, May-26, Volume: 275, Issue:21

    Topics: Animals; Bone Density; Endometrium; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Polyunsaturated Alkamides; Protein Binding; Raloxifene Hydrochloride; Rats; Rats, Wistar; Receptors, Estrogen; RNA, Messenger; Selective Estrogen Receptor Modulators; Tamoxifen; Transcortin; Tumor Cells, Cultured

2000
Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells. Mechanisms for its atheroprotective effects.
    The Journal of biological chemistry, 2000, Dec-08, Volume: 275, Issue:49

    Topics: Animals; Aorta; Cells, Cultured; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation; HeLa Cells; Humans; Muscle, Smooth, Vascular; Polyunsaturated Alkamides; Promoter Regions, Genetic; Rats; Receptor, IGF Type 1; Receptor, IGF Type 2; Receptors, Estrogen; Recombinant Proteins; Tamoxifen; Transfection

2000
Synergistic activation of the serotonin-1A receptor by nuclear factor-kappa B and estrogen.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:4

    Topics: Animals; Cells, Cultured; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Humans; NF-kappa B; Polyunsaturated Alkamides; Promoter Regions, Genetic; Protein Structure, Tertiary; Receptors, Estrogen; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Tamoxifen; Transcriptional Activation

2001
Effects of estrogenic compounds on human spermatozoa: evidence for interaction with a nongenomic receptor for estrogen on human sperm membrane.
    Molecular and cellular endocrinology, 2001, Jun-10, Volume: 178, Issue:1-2

    Topics: Acrosome Reaction; Benzhydryl Compounds; Calcium Signaling; Cell Membrane; Estradiol; Estrogen Receptor Modulators; Estrogens; Humans; In Vitro Techniques; Male; Octoxynol; Phenols; Polyunsaturated Alkamides; Progesterone; Receptors, Estrogen; Spermatozoa; Tamoxifen

2001
Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:11

    Topics: Amino Acid Sequence; Animals; Cells, Cultured; Coenzyme A; Cricetinae; DEAD-box RNA Helicases; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Histone Acetyltransferases; Humans; Ligands; Molecular Sequence Data; Mutation; Nuclear Receptor Coactivator 1; Phosphorylation; Polyunsaturated Alkamides; Protein Conformation; Protein Kinases; Protein Structure, Tertiary; Rabbits; Receptors, Estrogen; RNA Helicases; Tamoxifen; Trans-Activators; Transcription Factors

2001
Resistance to different antiestrogens is caused by different multi-factorial changes and is associated with reduced expression of IGF receptor Ialpha.
    Endocrine-related cancer, 2003, Volume: 10, Issue:4

    Topics: Blotting, Western; Breast Neoplasms; Cell Fusion; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Flow Cytometry; Fulvestrant; Humans; Insulin-Like Growth Factor Binding Protein 2; Microscopy, Phase-Contrast; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-bcl-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

2003
Biology and mode of action of pure antioestrogens.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Animals; Antineoplastic Agents; Binding, Competitive; Estradiol; Estrogen Receptor Modulators; Female; Mammary Neoplasms, Experimental; Ovariectomy; Polyunsaturated Alkamides; Rats; Tamoxifen; Uterus

1989
Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2006, Volume: 16, Issue:4

    Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Proteins; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Polyunsaturated Alkamides; Receptor, IGF Type 1; Tamoxifen

2006
Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT.
    Cancer letters, 2007, Oct-28, Volume: 256, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Breast Neoplasms; Casein Kinase II; Caspases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-bcl-2; Tamoxifen; Time Factors; Transfection

2007
Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer.
    Breast cancer research and treatment, 2011, Volume: 125, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fluorescent Antibody Technique; Gene Silencing; Humans; Neoplasm Metastasis; Polycomb Repressive Complex 2; Polymerase Chain Reaction; Polyunsaturated Alkamides; Prognosis; RNA, Messenger; RNA, Small Interfering; Tamoxifen; Transcription Factors; Treatment Outcome

2011