hydrazine and glycine
hydrazine has been researched along with glycine in 115 studies
Research
Studies (115)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 62 (53.91) | 18.7374 |
1990's | 3 (2.61) | 18.2507 |
2000's | 15 (13.04) | 29.6817 |
2010's | 30 (26.09) | 24.3611 |
2020's | 5 (4.35) | 2.80 |
Authors
Authors | Studies |
---|---|
Stone, WE | 1 |
Basile, M; Fenech, G; Larizza, A; Monforte, P; Previtera, T | 1 |
Gerdes, H; Mosebach, KO; Müller, R; Scheuer, A | 1 |
Bhatt, MV; Ramamurthy, B | 1 |
Hua, HY; Li, QT; Ren, YF; Wang, QD; Zhang, TM; Zhang, X | 1 |
Gibson, D; Levanon, M; Smithies, O | 1 |
Brambilla, G; Cavanna, M; Della Loggia, R; Furlani, A; Maura, A; Parodi, S; Scarcia, V | 1 |
Bassett, EW; Beiser, SM; Tanenbaum, SW | 1 |
Banaschak, H; Woelke, D | 2 |
Horecker, BL; Pontremoli, S; Sia, CL; Traniello, S | 1 |
Cappugi, G; Nassi, P; Ramponi, G; Treves, C | 1 |
Davidson, N; Robberson, DL | 1 |
Fietzek, PP; Hopper, KE; Kühn, K; Rexrodt, FW | 1 |
Derappe, C; Magnin, P; Rips, R | 1 |
Bone, A; Dawson, J | 1 |
Iversen, LL; Johnston, GA | 1 |
Turner, JM; Willetts, AJ | 1 |
Heymann, E; Iglesia, J | 1 |
Bailey, PT; Bose, S; Pradhan, SN; Thoa, NB | 1 |
Fastrez, J; Fersht, AR | 1 |
Bump, S; Deyl, Z; Rosmus, J | 1 |
Kaback, HR; Stadtman, ER | 1 |
Mole, KH; Shepherd, DM | 1 |
Bohak, Z; Naider, F | 1 |
Ishii, S; Kasai, K; Takai, Y; Watanabe, T | 1 |
Kalnitsky, G; Spadari, S; Subramanian, AR | 1 |
Grimek, HJ; McShan, WH; Nuti, LC | 1 |
Lallier, R | 1 |
Anderson, FE; Fedorchuk, M; Shetty, BV; Thomas, TL | 1 |
Curtis, DR; Duggan, AW; Johnston, GA | 1 |
Brezík, Z; Neuwirt, J; Ponka, P; Sperl, M | 1 |
Brambilla, G; Caraceni, CE; Cavanna, M; Parodi, S | 1 |
Spiro, MJ | 1 |
Neuwirt, J; Ponka, P | 1 |
Christomanos, AA | 1 |
Collot, D; Duranton, J; Guignery, G | 1 |
López-Mendoza, D; Villa-Treviño, S | 1 |
Baldini, L; Brambilla, G; Cavanna, M; Parodi, S | 3 |
Phillips, DM | 1 |
Farid, SA; Kozloff, LM | 1 |
Phillips, DM; Simson, P | 1 |
Honda, I; Kanaoka, M; Naruse, M; Sakakibara, S | 1 |
Gracy, RW; Horecker, BL; Lacko, AG | 1 |
Mayoh, H; Rothstein, M | 1 |
Lorand, L; Ong, HH | 1 |
Baldini, L; Brambilla, G; Cavanna, M | 1 |
Ho, TL; McCrae, GI; Nestor, JJ; Vickery, BH | 1 |
Cornell, NW; Kerich, MJ; Straight, CB; Zuurendonk, PF | 1 |
Baker, PR; Reid, AD | 1 |
Kamo, M; Miyatake, N; Satake, K; Tsugita, A | 1 |
Abruzzo, G; Bartizal, K; Dufresne, C; Milligan, J; Onishi, J; Patchett, A; VanMiddlesworth, F; Wilson, K | 1 |
Ellis, SW; Hayhurst, GP; Lennard, MS; Mackman, R; Ortiz de Montellano, PR; Smith, G; Tschirret-Guth, RA; Tucker, GT; Wolf, CR | 1 |
Branlant, G; Marchal, S | 1 |
He, J; Hnatowich, DJ; Rusckowski, M; Su, ZF | 1 |
DEFRANCESCHI, A; ZAMBONI, V | 1 |
BALDINI, L; BRAMBILLA, G; MATTIOLI, F | 1 |
ROEHNERT, H | 1 |
KOCH, A; LWOFF, A; LWOFF, M | 1 |
GUHA, SR | 1 |
ACKERMANN, E; LANGE, P; OEHME, P; REX, H | 1 |
WINSTEAD, JA; WOLD, F | 1 |
DREWS, J; FOELSCH, E; GRUNZE, H | 1 |
AMENTA, JS; DOMINGUEZ, AM | 1 |
DICKERSON, DR; FINGER, GC; ORLOPP, DE; STARR, LD | 1 |
Chang, RS; Chen, TB; Conn, PJ; Duggan, ME; Ha, SN; Jacobson, MA; Lemaire, W; Lindsley, CW; O'Brien, JA; Pettibone, DJ; Sur, C; Williams, DL; Wisnoski, DD | 1 |
Coote, JH; Smith, L; Yang, Z | 1 |
Radom, L; Sandala, GM; Smith, DM | 1 |
Boerman, OC; Broekema, M; Corstens, FH; Harris, TD; Liskamp, RM; Oyen, WJ; van Eerd, JJ | 1 |
Koizumi, J; Makita, H; Nakahara, Y; Ohno, K; Takeda, M | 1 |
Gudasi, KB; Nethaji, M; Patil, MS; Patil, SA; Shenoy, RV; Vadavi, RS | 1 |
Adamson, CS; Aman, MJ; Burke, TR; Fisher, RJ; Freed, EO; Gousset, K; Liu, F; Stephen, AG | 1 |
Balakrishnan, V; Trussell, LO | 1 |
Chan, MH; Chen, HH; Chiu, PH; Sou, JH | 1 |
Baker, GB; Chen, QH; Davood, A; Fassihi, A; Knaus, EE; MacKenzie, EM; Rauw, G | 1 |
Abdie, N; Ebrahimi, F; Gandomkar, M; Goudarzi, M; Heydarpor, HR; Mazidi, M; Mirfallah, SH; Najafi, R; Shafiei, M | 1 |
Biagini, S; Blower, PJ; King, R; Mather, SJ; Surfraz, MB | 1 |
Destache, CJ; Ohia, SE; Opere, CA; Zhao, M | 1 |
Bouillaud, F; Brouillard, F; Colas, J; Edelman, A; Fritsch, J; Kelly, M; Nguyen-Khoa, T; Ollero, M; Trudel, S | 1 |
Hornung, J; Mannowetz, N; Raubuch, M; Ruffing, U; Wandernoth, P; Wennemuth, G | 1 |
Halm, DR; Halm, ST; He, Q; Zhang, J | 1 |
Anderson, KL; Davis, MJ; DiMagno, MJ; O'Riordan, MX; Radtke, AL; Swanson, JA | 1 |
Barman, PP; Choisy, SC; Gadeberg, HC; Hancox, JC; James, AF | 1 |
Choy, RK; de Hostos, EL; Nguyen, T | 1 |
Brubacher, MB; Forrest, JN; Stahl, K; Stahl, M | 1 |
Sheppard, DN | 1 |
Chakraborty, R; Chelikani, P; Dakshinamurti, S; Gleim, S; Hwa, J; Pydi, SP | 1 |
Alexander, C; Dawson, DC; Frye, L; Ivetac, A; Norimatsu, Y; O'Donnell, N; Sansom, MS | 1 |
Busiah, K; Edelman, A; Polak, M; Scharfmann, R; Zertal-Zidani, S | 1 |
Cuthbert, AW; Garnett, JP; Gray, MA; Hickman, E; Tunkamnerdthai, O | 1 |
Avcı, CB; Durkan, K; Gündüz, C; Ozgür, A; Susluer, SY; Yurt Lambrecht, F | 1 |
Hongeng, S; Muanprasat, C; Pathomthongtaweechai, N; Satitsri, S; Wongborisuth, C | 1 |
Frei, AP; Moest, H; Novy, K; Wollscheid, B | 1 |
Abedi, SM; Hosseinimehr, SJ; Noaparast, Z; Varmira, K | 1 |
Halonen, P; Hukasova, E; Kallio, L; Kallio, MJ; Laine, LJ; Lindqvist, A; Mäki-Jouppila, JH; Narvi, E; Poso, A; Rehnberg, J; Tiikkainen, P | 1 |
Bendahhou, S; Cougnon, M; Duranton, C; Giuliano, S; Melis, N; Rubera, I; Tauc, M | 1 |
Edlund, A; Eliasson, L; Esguerra, JL; Flodström-Tullberg, M; Wendt, A | 1 |
Cabral, P; Fernandez, M; Gallazzi, F; Gambini, JP; Garcia, MF; Moreno, M; Porcal, W; Quinn, TP; Zhang, X | 1 |
Calkovska, A; Calkovsky, V; Franova, S; Joskova, M; Kolomaznik, M; Smolarova, S; Uhliarova, B | 1 |
Cui, G; McCarty, NA | 1 |
Clauss, WG; Fronius, M; Vitzthum, C | 1 |
Cui, G; Imhoff, BR; Infield, DT; Khazanov, N; McCarty, NA; Senderowitz, H; Stauffer, BB | 1 |
Desai, A; Gong, T; Lu, P; Wang, M; Zeng, D; Zhang, K | 1 |
Clauzure, M; Massip-Copiz, M; Mori, C; Santa-Coloma, TA; Valdivieso, ÁG | 1 |
Abedi, SM; Ahmadpour, S; Hosseinimehr, SJ; Noaparast, Z | 1 |
Adam, D; Bilodeau, C; Brochiero, E; Maillé, É; Ruffin, M; Sognigbé, L | 1 |
Cheng, D; Li, B; Lin, QY; Meng, L; Shi, H; Tan, H; Zhang, Y | 1 |
Chenoweth, DM; Harris, T | 1 |
Chung, D; Diab, V; Drullinsky, P; Giralt, S; Hassoun, H; Hultcrantz, M; Korde, N; Lahoud, O; Landau, H; Landgren, O; Lendvai, N; Lesokhin, A; Mailankody, S; Mastey, D; Salcedo, M; Schlossman, J; Scordo, M; Shah, G; Shah, U; Smith, E; Werner, K | 1 |
Emala, CW; Heras, AF; Perez-Zoghbi, J; Silver, RB; Veerappan, A; Worgall, S; Worgall, TS | 1 |
Callaghan, PJ; Ferrick, B; Mullin, JM; Rybakovsky, E; Thomas, S | 1 |
Aguirre, DQ; Cai, W; Del Rio Flores, A; Dror, MJ; Du, Y; Geng, J; Narayanamoorthy, M; Sato, M; Twigg, FF; Zhai, R; Zhang, W; Zill, NA | 1 |
Bailey, SJ; Brand, K; Causer, AJ; Cummings, MH; Khalaf, M; Klein Rot, E; Saynor, ZL; Shepherd, AI; Shute, JK; Smith, J | 1 |
Reviews
2 review(s) available for hydrazine and glycine
Article | Year |
---|---|
Developing novel antisecretory drugs to treat infectious diarrhea.
Topics: Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Escherichia coli; Glycine; Humans; Hydrazines; Models, Animal; Proanthocyanidins; Rotavirus; Thiazolidines; Vibrio cholerae | 2011 |
Magic year for multiple myeloma therapeutics: Key takeaways from the ASH 2015 annual meeting.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Boron Compounds; Congresses as Topic; Glycine; Humans; Hydrazines; Molecular Targeted Therapy; Multiple Myeloma; Proteasome Inhibitors; Protein Kinase Inhibitors; Signal Transduction; Thiadiazoles; Treatment Outcome; Triazoles | 2017 |
Trials
1 trial(s) available for hydrazine and glycine
Article | Year |
---|---|
Phase I Study of Selinexor, Ixazomib, and Low-dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Dexamethasone; Female; Glycine; Humans; Hydrazines; Male; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Triazoles | 2020 |
Other Studies
112 other study(ies) available for hydrazine and glycine
Article | Year |
---|---|
Effects of alterations in the metabolism of gamma-aminobutyrate on convulsant potencies.
Topics: 3-Mercaptopropionic Acid; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Diacetyl; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Hydrazines; Male; Mice; Pentylenetetrazole; Phenelzine; Picrotoxin; Pyridoxine; Reaction Time; Seizures; Thiones; Valproic Acid | 1977 |
[Piperazine-2,5-diones N,N'-substituted. I. Action of some hydrazines on ethyl ester of N-phenyl-N-chloroacetylglycine].
Topics: Azepines; Cyclization; Glycine; Hydrazines; Indicators and Reagents; Piperazines | 1979 |
[Glycine hydrazide as a bifunctional reagent for the synthesis of antigens with steroids as the immunodeterminant groups (author's transl)].
Topics: Animals; Antibodies; Antibody Specificity; Antigens; Cattle; Glycine; Hydrazines; Rabbits; Serum Albumin, Bovine; Testosterone | 1976 |
Synthesis and antitubercular activity of N-(2-naphthyl)glycine hydrazide analogues.
Topics: Antitubercular Agents; Chemical Phenomena; Chemistry; Glycine; Hydrazines; Mycobacterium tuberculosis; Naphthalenes | 1989 |
[Observation on the distribution of [14C] AT-1902 in mice].
Topics: Animals; Antineoplastic Agents; Autoradiography; Glycine; Hydrazines; Male; Mice; Tissue Distribution; Tumor Cells, Cultured | 1989 |
Heterogeneity of normal human immunoglobulin light chains. Nonallelic variation in the constant region of lambda chains.
Topics: Acetamides; Amino Acids; Autoanalysis; Bence Jones Protein; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cysteamine; Disulfides; Dithiothreitol; Fluoroacetates; gamma-Globulins; Glycine; Humans; Hydrazines; Immunoglobulin G; Immunoglobulins; Iodoacetates; Methods; Peptides; Polymorphism, Genetic; Protein Denaturation; Serine; Sulfides; Trypsin; Urea | 1971 |
The immunodepressive activity of N-diazoacetylglycine derivatives in mice.
Topics: Alkylating Agents; Amides; Animals; Antibody-Producing Cells; Azo Compounds; Cysteine; Dose-Response Relationship, Drug; Erythrocytes; Esters; Female; Glycine; Graft vs Host Reaction; Hemolysin Proteins; Hydrazines; Immunoglobulin M; Immunosuppression Therapy; Immunosuppressive Agents; Lethal Dose 50; Male; Mice; Mice, Inbred BALB C; Sheep; Skin Transplantation; Transplantation, Autologous | 1973 |
Studies in immunoglobulin chemistry. I. Reinvestigation of the C-terminal amino acids of 6.5S rabbit and human gamma-globulins.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; gamma-Globulins; Glycine; Humans; Hydrazines; In Vitro Techniques; Peptides; Rabbits; Serine; Species Specificity; Sulfonic Acids | 1966 |
[Amino acid transport and metabolism of erythrocytes under the effect of hydrazine acetic acid].
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cell Membrane; Chickens; Chromatography, Paper; Ducks; Erythrocytes; Glucose; Glutathione; Glycine; Humans; Hydrazines; Indicators and Reagents; Methemoglobin; Perchlorates | 1968 |
Studies on the subunit structure of rabbit liver fructose diphosphatase.
Topics: Alanine; Anhydrides; Animals; Detergents; Electrophoresis, Disc; Fructose-Bisphosphatase; Glycine; Hydrazines; Liver; Maleates; Methods; Molecular Weight; Rabbits; Sulfates; Ultracentrifugation | 1969 |
Preliminary studies on horse muscle acylphosphatase structure. Evidence of a mixed disulfide with glutathione.
Topics: Acetates; Amino Acids; Anhydrides; Animals; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis; Formates; Glutamates; Glutathione; Glycine; Histidine; Hydrazines; Iodoacetates; Mercaptoethanol; Muscles; Naphthalenes; Oxidation-Reduction; Phosphoric Monoester Hydrolases; Sulfides; Sulfonic Acids; Tritium; Tyrosine; Urea | 1971 |
Covalent coupling of ribonucleic acid to agarose.
Topics: Adenine Nucleotides; Aldehydes; Alkaline Phosphatase; Amides; Aminocaproates; Cyanogen Bromide; Dimethyl Sulfoxide; DNA, Bacterial; Escherichia coli; Glycine; Hydrazines; Hydrogen-Ion Concentration; Imines; Kinetics; Methods; Methylamines; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Oxidation-Reduction; Periodic Acid; Polysaccharides; RNA; RNA, Ribosomal; RNA, Transfer; Uracil Nucleotides | 1972 |
The covalent structure of collagen. 2. The amino-acid sequence of alpha1-CB7 from calf-skin collagen.
Topics: Amino Acid Sequence; Amino Acids; Animals; Autoanalysis; Cattle; Collagen; Glycine; Hydrazines; Hydrolysis; Hydroxylation; Hydroxylysine; Hydroxyproline; Microbial Collagenase; Peptide Chain Termination, Translational; Peptide Fragments; Proline | 1973 |
Chemical structure and pharmacological activity of glycine derivatives. Influence of disubstitution of the amine function of glycine esters and hydrazides.
Topics: Amines; Animals; Antihypertensive Agents; Cats; Central Nervous System; Deanol; Glycine; Guinea Pigs; Histamine H1 Antagonists; Hydrazines; Mice; Monoamine Oxidase Inhibitors; Rabbits; Rats | 1965 |
The effect of thiols and ganglioside on the alterations in water, sodium and potassium distribution produced in brain slices by vasopressin and protamine.
Topics: Animals; Brain; Cysteine; Gangliosides; Glycine; Glycolates; Guinea Pigs; Hydrazines; In Vitro Techniques; Potassium; Protamines; Reserpine; Sodium; Thioglycolates; Vasopressins; Water-Electrolyte Balance | 1966 |
Glycine uptake in rat central nervous system slices and homogenates: evidence for different uptake systems in spinal cord and cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport, Active; Carbon Isotopes; Cerebellum; Cerebral Cortex; Chlorpromazine; Chromatography, Paper; Desipramine; Ethylmaleimide; Glycine; Hydrazines; Imipramine; Medulla Oblongata; Mesencephalon; Neurotransmitter Agents; Pons; Rats; Spinal Cord; Synaptic Vesicles; Tritium | 1971 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
[An investigation of the microheterogeneity and the subunit structure of carboxylestereases by the quanititative determination of the terminal amino acids].
Topics: Amino Acid Sequence; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Esterases; Glycine; Hydrazines; Hydrolysis; Isoelectric Focusing; Kidney; Leucine; Liver; Molecular Weight; Swine | 1974 |
Effects of 5-hydroxytryptophane on self-stimulation in rats.
Topics: 5-Hydroxytryptophan; Animals; Brain; Caudate Nucleus; Cerebral Cortex; Diencephalon; Dose-Response Relationship, Drug; Electrodes, Implanted; Glutamates; Glycine; Hydrazines; Hypothalamus; Injections, Intraperitoneal; Male; Medulla Oblongata; Mesencephalon; Myocardium; Norepinephrine; Pons; Rats; Self Stimulation; Serotonin | 1974 |
Demonstration of the acyl-enzyme mechanism for the hydrolysis of peptides and anilides by chymotrypsin.
Topics: Acylation; Alanine; Anilides; Benzoates; Binding, Competitive; Chemical Phenomena; Chemistry; Chymotrypsin; Dimethylformamide; Electrophoresis, Paper; Esters; Glycine; Hydrazines; Hydrolysis; Kinetics; Mathematics; Methyl Ethers; Nitrobenzenes; Osmolar Concentration; Peptides; Phenylalanine; Quaternary Ammonium Compounds; Structure-Activity Relationship; Thermodynamics; Tritium | 1973 |
Studies on the structure of collagen. II. The nature of the N- and C-terminals in enzyme-treated and untreated collagen.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cattle; Chymotrypsin; Collagen; Glycine; Hydrazines; Indicators and Reagents; Leucine; Lysine; Naphthalenes; Nitrobenzenes; Pepsin A; Peptide Hydrolases; Phenylalanine; Skin | 1967 |
Glycine uptake in Escherichia coli. II. Glycine uptake, exchange, and metabolism by an isolated membrane preparation.
Topics: Alanine; Arsenic; Autoradiography; Azides; Biological Transport; Carbon Isotopes; Cell Membrane; Chromatography, Thin Layer; Cold Temperature; Cyanides; Dinitrophenols; Escherichia coli; Glucose; Glycine; Helium; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Iodoacetates; Magnesium; Mercury; Nucleotides; Phosphatidylethanolamines; Serine; Sulfonic Acids; Threonine | 1968 |
[Effect of hydrazinoacetic acid on the incorporation of glycine in E. coli].
Topics: Acetates; Carbon Isotopes; Depression, Chemical; Escherichia coli; Glycine; Hydrazines; Pyridoxal Phosphate | 1968 |
Inhibition of histidine decarboxylases in vitro.
Topics: Amino Acids; Animals; Carboxy-Lyases; Dialysis; Female; Glycine; Guinea Pigs; Histidine; Hydrazines; Hydroxylamines; Imidazoles; In Vitro Techniques; Isoquinolines; Kidney; Phenethylamines; Phenylalanine; Propionates; Protein Binding; Pyridoxal Phosphate; Rats; Spectrum Analysis; Stomach; Ultraviolet Rays | 1972 |
Regeneration of methionyl residues from their sulfonium salts in peptides and proteins.
Topics: Acetates; Acetophenones; Alkylation; Bromine; Chemical Phenomena; Chemistry; Chymotrypsin; Electrophoresis, Paper; Enzyme Activation; Formates; Glycine; Hydrazines; Hydroxylamines; Kinetics; Mercaptoethanol; Methionine; Oxidation-Reduction; Peptides; Phenols; Sulfhydryl Compounds; Sulfides | 1972 |
The carboxyl terminal amino acid residues of human and horse prothrombins.
Topics: Amino Acids; Animals; Barium; Cellulose; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Citrates; Electrophoresis, Disc; Electrophoresis, Paper; Glutamates; Glycine; Horses; Humans; Hydrazines; Ion Exchange Resins; Isotope Labeling; Prothrombin; Tritium | 1971 |
The terminal residues of aspergillopeptidase B.
Topics: Alanine; Aspergillus; Chromatography, Paper; Chromatography, Thin Layer; Fluorine; Glycine; Hydrazines; Kinetics; Nitrobenzenes; Peptide Hydrolases; Protein Conformation; Protein Denaturation | 1971 |
Carbohydrate and end group analyses of ovine FSH.
Topics: Amino Acid Sequence; Animals; Carbohydrates; Dansyl Compounds; Follicle Stimulating Hormone; Fucose; Glutamates; Glycine; Glycoproteins; Hexosamines; Hexoses; Hydrazines; Neuraminic Acids; Serine; Sheep | 1971 |
Effects of various inhibitors of protein cross-linking on the formation of fertilization membrane in sea urchin egg.
Topics: Animals; Benzyl Compounds; Cell Membrane; Collagen; Elastin; Female; Fertilization; Glycine; Hydrazines; Isoniazid; Mercaptoethanol; Ovum; Penicillamine; Protein Biosynthesis; Sea Urchins; Time Factors | 1971 |
The synthesis and activity of some 3-substituted 1,2,3,4-pseudooxatriazol-5-ones and their precursors and related compounds.
Topics: Animals; Blood Pressure; Bridged-Ring Compounds; Cats; Depression, Chemical; Dogs; Glycine; Guanidines; Heart Rate; Hydrazines; Injections, Intravenous; Mice; Nitroso Compounds; Rats; Semicarbazides; Thiosemicarbazones | 1970 |
The inactivation of extracellularly administered amino acids in the feline spinal cord.
Topics: Action Potentials; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Benzene Derivatives; Benzoates; Biological Transport; Brain; Cats; Depression, Chemical; Drug Synergism; Glycine; Hydrazines; Interneurons; Lysine; Mercury; Motor Neurons; Neurons; Propionates; Rats; Spinal Cord; Stimulation, Chemical; Sulfonic Acids; Synapses; Thiosemicarbazones | 1970 |
The ability of exogenous heme to restore globin synthesis in reticulocytes with impaired heme formation.
Topics: Amino Acids; Animals; Blood Proteins; Bloodletting; Carbon Isotopes; Cycloheximide; Depression, Chemical; Globins; Glycine; Heme; Hemoglobins; Hydrazines; Isonicotinic Acids; Methionine; Peptide Biosynthesis; Rabbits; Radioisotopes; Reticulocytes; Selenium; Stimulation, Chemical; Time Factors | 1970 |
[Carcinogenic activity of two N-diazoacetyl derivatives of glycine in newborn Swiss mice].
Topics: Amides; Animals; Azo Compounds; Carcinogens; Glycine; Hydrazines; Mice; Neoplasms, Experimental | 1970 |
Studies on the protein portion of thyroglobulin. Amino acid compositions and terminal amino acids of several thyroglobulins.
Topics: Alanine; Amides; Amino Acids; Animals; Aspartic Acid; Carboxypeptidases; Cattle; Cystine; Fluorine; Glutamates; Glycine; Humans; Hydrazines; Iodine; Leucine; Monosaccharides; Nitrobenzenes; Serine; Sheep; Swine; Thyroglobulin; Thyroid Gland | 1970 |
The use of reticulocytes with high non-haem iron pool for studies of regulation of haem synthesis.
Topics: Animals; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Glycine; Heme; Hydrazines; In Vitro Techniques; Iron; Iron Isotopes; Isonicotinic Acids; Rabbits; Reticulocytes; Transferrin | 1970 |
[Constitution of the hemoglobin of the toad Bufo bufo spinosus].
Topics: Alanine; Amino Acids; Animals; Anura; Arginine; Chromatography, Gel; Formates; Glycine; Hemoglobins; Histidine; Hydrazines; Lysine; Methionine; Peptide Hydrolases; Serine; Spectrum Analysis | 1970 |
[Comparative study of C-terminal amino acids of holochromic and cytoplasmic proteins in normal and etiolated plantules of Zea mays L].
Topics: Alanine; Amino Acids; Chloroplasts; Glycine; Hydrazines; Plant Proteins; Tritium; Zea mays | 1970 |
Hydrazine-induced inhibition of amino acid incorporation into rat liver protein.
Topics: Animals; Autoradiography; Carbon Isotopes; Depression, Chemical; Fatty Liver; Glycine; Hydrazines; Leucine; Lipoproteins; Liver; Male; Pancreas; Protein Biosynthesis; Rats; Spleen | 1971 |
[Systemic toxicity of N-diazoacetylglycine hydrazide in various animal species].
Topics: Animals; Blood Cell Count; Diuresis; Dogs; Glycine; Hydrazines; Injections, Intravenous; Mice; Nitrogen; Rabbits; Rats | 1968 |
[Immunosuppressive action in mice of diazoacetylglycine amide and diazoacetylglycine hydrazide in compairison to methotrexate].
Topics: Amides; Animals; Glycine; Hydrazines; Immunosuppressive Agents; Methotrexate; Mice | 1968 |
Loss of C-terminal amino acids by hydrazidation during hydrazinolysis.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Glycine; Hydrazines; Lysine | 1968 |
[Action of N-diazoacetylglycine hydrazide on hepatic regeneration and embryonal development in cats].
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Glycine; Hydrazines; Liver Regeneration; Male; Pregnancy; Rats | 1968 |
Number of polypeptide components in bacteriophage T2L contractile sheaths.
Topics: Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Coliphages; Glutamine; Glycine; Hydrazines; Leucine; Peptides; Serine; Threonine; Tryptophan; Valine | 1968 |
The C-terminal amino acids and sequences of calf and rat thymus histones.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Autoanalysis; Carboxypeptidases; Cattle; Electrophoresis; Glycine; Histones; Hydrazines; Lysine; Molecular Weight; Rats; Species Specificity; Thymus Gland; Tritium | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Subunit structure and chemical properties of rabbit liver aldolase.
Topics: Amino Acids; Animals; Carboxypeptidases; Chromatography, Gel; Detergents; Electrophoresis, Disc; Fructose-Bisphosphate Aldolase; Glycine; Guanidines; Hydrazines; Liver; Methionine; Methods; Molecular Weight; Muscles; Organ Specificity; Rabbits; Serine; Sulfates; Tyrosine; Ultracentrifugation | 1969 |
Glycine synthesis and isocitrate lyase in the nematode, Caenorhabditis briggsae.
Topics: Acetates; Alanine; Animals; Aspartic Acid; Chromatography, Paper; Dinitrophenols; Glycine; Hydrazines; In Vitro Techniques; Lyases; Nematoda; Serine | 1964 |
Labeling of amine-acceptor cross-linking sites of fibrin by transpeptidation.
Topics: Acyltransferases; Chemical Phenomena; Chemistry; Fibrin; Glycine; Hydrazines; Hydroxylamines; Nitrites; Ultracentrifugation | 1966 |
[Diazo derivatives of amino acids and peptides as possible antineoplastic chemotherapeutic agents. XII. Experimental antineoplastic activity of hydrazone derivatives of N-diazoacetylglycine hydrazide].
Topics: Animals; Antineoplastic Agents; Azo Compounds; Glycine; HeLa Cells; Hydrazines; In Vitro Techniques; Mice; Sarcoma, Experimental | 1966 |
Hydrophobic, aza-glycine analogues of luteinizing hormone-releasing hormone.
Topics: Animals; Biological Assay; Chromatography, High Pressure Liquid; Estrus; Female; Glycine; Gonadotropin-Releasing Hormone; Hydrazines; Indicators and Reagents; Pregnancy; Rats; Structure-Activity Relationship | 1984 |
Selective inhibition of alanine aminotransferase and aspartate aminotransferase in rat hepatocytes.
Topics: Alanine Transaminase; Alkynes; Aminobutyrates; Aminooxyacetic Acid; Animals; Aspartate Aminotransferases; Cycloserine; Glycine; Hydrazines; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains | 1984 |
Formation and separation by reversed-phase high-performance liquid chromatography of fluorescent and UV-absorbing bile salt derivatives.
Topics: Animals; Bile Acids and Salts; Chromatography, High Pressure Liquid; Dansyl Compounds; Glycine; Humans; Hydrazines; Phenylhydrazines; Taurine | 1983 |
Specific chemical cleavage of asparaginyl and glycyl-glycine bonds in peptides and proteins by anhydrous hydrazine vapor.
Topics: Amino Acid Sequence; Amino Acids; Anhydrides; Animals; Asparagine; Chemical Fractionation; Electrophoresis, Polyacrylamide Gel; Glycine; Hydrazines; Molecular Sequence Data; Peptides; Proteins; Spectrometry, Mass, Fast Atom Bombardment | 1994 |
Carbazate as a glycine bioisostere in restricticin.
Topics: Animals; Antifungal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Stability; Enzyme Inhibitors; Fungi; Glycine; Hydrazines; Hydrolysis; In Vitro Techniques; Mice; Molecular Structure; Oxidoreductases; Pyrans; Stereoisomerism; Sterol 14-Demethylase | 1996 |
Active-site topologies of human CYP2D6 and its aspartate-301 --> glutamate, asparagine, and glycine mutants.
Topics: Asparagine; Aspartic Acid; Binding Sites; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Electrochemistry; Glutamic Acid; Glycine; Humans; Hydrazines; Imines; Mixed Function Oxygenases; Models, Molecular; Molecular Structure; Mutation; Protoporphyrins; Saccharomyces cerevisiae; Structure-Activity Relationship | 1996 |
Engineered nonphosphorylating glyceraldehyde 3-phosphate dehydrogenase at position 268 binds hydroxylamine and hydrazine as acyl acceptors.
Topics: Binding Sites; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Hydrazines; Hydroxylamine; Mutagenesis; Phosphorylation; Protein Binding | 2001 |
In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands.
Topics: Blood Proteins; Cells, Cultured; Edetic Acid; Endothelium, Vascular; Glycine; Humans; Hydrazines; Integrins; Ligands; Metabolic Clearance Rate; Nicotinic Acids; Oligopeptides; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Umbilical Veins | 2003 |
Identification of two metabolites of isoniazid (isonicotinoylglycine and 1-isonicotinoyl-2-acetylhydrazine) by paper chromatography in rat urine.
Topics: Animals; Chromatography; Chromatography, Paper; Glycine; Hydrazines; Isoniazid; Nicotinic Acids; Rats; Urine | 1954 |
[Diazo derivatives of amino acids and peptides as possible antineoplastic chemotherapeutic agents. VI. Experimental anticancerigenic activity of diazoacetylglycine hydrazide].
Topics: Amino Acids; Anti-Bacterial Agents; Antineoplastic Agents; Azo Compounds; Fabaceae; Glycine; Hydrazines; Peptides | 1961 |
[On hydrazine compounds of substituted amino acids. 1. Glycylhydrazine compounds].
Topics: Amino Acid Substitution; Fabaceae; Glycine; Hydrazines | 1962 |
[THE PROBLEM OF THE SPECIFICITY OF GUANIDINE FOR THE DEVELOPMENT OF A GUANIDINE-REQUIRING MUTANT OF POLIOVIRUS].
Topics: Adenine; Amino Acids; Arginine; Creatine; Creatinine; Enterovirus C, Human; Glycine; Guanidine; Guanidines; Hydrazines; Metabolism; Mutation; Ornithine; Poliovirus; Research; Uracil; Urea | 1963 |
EFFECT OF HYDRAZINE ACETIC ACID ETHYL ESTER AND ITS GLYCYL DERIVATIVE ON OXIDATION AND AMMONIA FORMATION IN RAT BRAIN TISSUES.
Topics: Acetates; Amino Acids; Ammonia; Brain; Glucose; Glutamates; Glycine; Hydrazines; Ketoglutaric Acids; Metabolism; Oxalates; Oxidation-Reduction; Pharmacology; Pyruvates; Rats; Research; Succinates | 1964 |
[STUDIES ON THE CENTRAL NERVOUS EFFECT OF HYDRAZINOACETIC ACID AND ITS DERIVATIVES].
Topics: Acetates; Adjuvants, Anesthesia; Body Temperature; Central Nervous System; Electroencephalography; Glycine; Hexobarbital; Hydrazines; Mice; Pharmacology; Pyridoxine; Rats; Research; Reserpine; Toxicology | 1964 |
STUDIES ON THE CARBOXYL- AND AMINO-TERMINAL RESIDUES OF RABBIT MUSCLE ALDOLASE.
Topics: Amino Acids; Animals; Carboxypeptidases; Chemical Phenomena; Chemistry; Fructose-Bisphosphate Aldolase; Glycine; Hydrazines; Models, Theoretical; Muscles; Peptides; Rabbits; Research; Serine | 1964 |
[ON THE EFFECT OF A NEW CYTOSTATIC (RO-4-6467) ON THE INCORPORATION OF LABELLED GLYCINE IN TUMOR CELLS].
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cytostatic Agents; Glycine; Humans; Hydrazines; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Research | 1964 |
THE EFFECT OF HYDRAZINE AND CONGENERS ON C14-O2 RESPIRATORY PATTERN OF VARIOUS METABOLIC SUBSTRATES.
Topics: 1,2-Dimethylhydrazine; Acetates; Alanine; Amino Acids; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Dimethylhydrazines; Fatty Acids; Glucose; Glycine; Hydrazines; Iproniazid; Lipid Metabolism; Metabolism; Pharmacology; Rats; Research; Toxicology | 1965 |
AROMATIC FLUORINE COMPOUNDS. 13. SUBSTITUTED N-PHENYLGLYCINE ETHYL ESTERS AND HYDRAZIDES.
Topics: Chemistry, Pharmaceutical; Esters; Fluorine; Fluorine Compounds; Glycine; Hydrazines; Organic Chemicals; Research | 1965 |
Difference in mGluR5 interaction between positive allosteric modulators from two structural classes.
Topics: Animals; Benzamides; Binding Sites; CHO Cells; Cricetinae; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrazines; Phthalimides; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Structure-Activity Relationship | 2003 |
Paraventricular nucleus activation of renal sympathetic neurones is synaptically depressed by nitric oxide and glycine acting at a spinal level.
Topics: Action Potentials; Animals; Arginine; Blood Pressure; Bronchodilator Agents; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Glycine; Glycine Agents; Homocysteine; Hydrazines; Injections, Spinal; Kidney; Male; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Spinal Cord; Strychnine; Sympathetic Nervous System; Synapses | 2004 |
Divergent mechanisms of suicide inactivation for ethanolamine ammonia-lyase.
Topics: Acetaldehyde; Cobamides; Enzyme Activation; Ethanolamine; Ethanolamine Ammonia-Lyase; Glycine; Hydrazines; Thermodynamics | 2005 |
Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci.
Topics: Abscess; Animals; Binding, Competitive; Chelating Agents; Escherichia coli Infections; Female; Glycine; Granulocytes; Humans; Hydrazines; In Vitro Techniques; Indium Radioisotopes; Isonicotinic Acids; Isotope Labeling; Leukotriene B4; Muscle, Skeletal; Nicotinic Acids; Organotechnetium Compounds; Rabbits; Radioligand Assay; Radiopharmaceuticals; Solubility; Structure-Activity Relationship; Tissue Distribution | 2005 |
Structural analysis of the sheath of a sheathed bacterium, Leptothrix cholodnii.
Topics: Biological Products; Chromatography, High Pressure Liquid; Cysteine; Fluorescent Dyes; Galactosamine; Glucosamine; Glycine; Hexuronic Acids; Hydrazines; Hydrolysis; Leptothrix; Lipids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Oxadiazoles; Peptides; Polysaccharides; Polysaccharides, Bacterial; Protein Structure, Tertiary | 2005 |
X-ray crystal structure of phenylglycine hydrazide: synthesis and spectroscopic studies of its transition metal complexes.
Topics: Cobalt; Copper; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Glycine; Hydrazines; Magnetic Resonance Spectroscopy; Manganese; Metals, Heavy; Models, Molecular; Molecular Conformation; Nickel; Phenols; Spectrophotometry; Spectrophotometry, Infrared; Zinc | 2007 |
Hydrazone- and hydrazide-containing N-substituted glycines as peptoid surrogates for expedited library synthesis: application to the preparation of Tsg101-directed HIV-1 budding antagonists.
Topics: Amino Acid Sequence; Anti-HIV Agents; DNA-Binding Proteins; Endosomal Sorting Complexes Required for Transport; Glycine; HIV-1; Hydrazines; Hydrazones; Oligopeptides; Peptide Library; Peptoids; Proline; Transcription Factors | 2006 |
Synaptic inputs to granule cells of the dorsal cochlear nucleus.
Topics: Animals; Auditory Pathways; Auditory Perception; Cell Size; Cochlear Nucleus; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hydrazines; Inhibitory Postsynaptic Potentials; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Synapses; Synaptic Transmission | 2008 |
Attenuation of ketamine-evoked behavioral responses by mGluR5 positive modulators in mice.
Topics: Animals; Behavior, Animal; Cognition Disorders; Excitatory Amino Acid Antagonists; Glycine; Hydrazines; Injections, Intraventricular; Ketamine; Male; Mice; Mice, Inbred ICR; Motor Activity; Phenylacetates; Postural Balance; Psychomotor Performance; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recognition, Psychology; Reflex, Startle | 2008 |
N-Propynyl analogs of beta-phenylethylidenehydrazines: synthesis and evaluation of effects on glycine, GABA, and monoamine oxidase.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Animals; Brain; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Glycine; Hydrazines; Male; Molecular Structure; Monoamine Oxidase; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship | 2008 |
Clinical evaluation of antimicrobial peptide [(99m)Tc/Tricine/HYNIC(0)]ubiquicidin 29-41 as a human-specific infection imaging agent.
Topics: Adult; Aged; Antimicrobial Cationic Peptides; Bacterial Infections; Female; Glycine; Humans; Hydrazines; Male; Middle Aged; Nicotinic Acids; Organotechnetium Compounds; Peptide Fragments; Quality Control; Radionuclide Imaging; Radiopharmaceuticals; Soft Tissue Infections; Tissue Distribution | 2009 |
Technetium-binding in labelled HYNIC-peptide conjugates: role of coordinating amino acids.
Topics: Animals; Cattle; Glutamic Acid; Glycine; Histidine; Hydrazines; Niacinamide; Peptides; Serum Albumin, Bovine; Spectrometry, Mass, Electrospray Ionization; Technetium | 2009 |
Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo.
Topics: Animals; Benzofurans; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Fatty Acids, Unsaturated; Flurbiprofen; Glutamic Acid; Glutamine; Glycine; Hydrazines; Isoprostanes; Neurotransmitter Agents; Nitrobenzenes; Prostaglandins; Receptors, Prostaglandin; Retina; Sulfonamides; Xanthones | 2009 |
Cystic fibrosis transmembrane regulator inhibitors CFTR(inh)-172 and GlyH-101 target mitochondrial functions, independently of chloride channel inhibition.
Topics: Aconitate Hydratase; Benzoates; Cell Line; Chloride Channels; Cystic Fibrosis Transmembrane Conductance Regulator; Glycine; Humans; Hydrazines; Interleukin-8; Membrane Potential, Mitochondrial; Mitochondria; Mutation; NF-kappa B; Oxidative Phosphorylation; Oxygen Consumption; Reactive Oxygen Species; Thiazolidines | 2010 |
Early activation of sperm by HCO(3) (-) is regulated hormonally in the murine uterus.
Topics: Animals; Benzoates; Bicarbonates; Cystic Fibrosis Transmembrane Conductance Regulator; Estrus; Female; Glycine; Hydrazines; Male; Mice; RNA, Messenger; Sexual Maturation; Sperm Capacitation; Sperm Motility; Spermatozoa; Thiazolidines; Uterus | 2011 |
Activation of the basolateral membrane Cl- conductance essential for electrogenic K+ secretion suppresses electrogenic Cl- secretion.
Topics: Animals; Cell Membrane; Chloride Channels; Chlorides; Cholinergic Agents; Colon; Dinoprostone; Epinephrine; Epithelial Cells; Glycine; Guinea Pigs; Hydrazines; Intestinal Mucosa; Male; Membrane Potentials; Membrane Proteins; Potassium; Sodium-Potassium-Chloride Symporters | 2011 |
Listeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome.
Topics: Animals; Bacterial Toxins; Benzoates; Calcium Channel Blockers; Cell Line; Cells, Cultured; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Female; Glycine; Heat-Shock Proteins; Hemolysin Proteins; Host-Pathogen Interactions; Hydrazines; Hydrogen-Ion Concentration; Listeria monocytogenes; Listeriosis; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; ortho-Aminobenzoates; Phagosomes; Protein Multimerization; Thiazolidines; Vacuoles | 2011 |
Cardiac ion channel current modulation by the CFTR inhibitor GlyH-101.
Topics: Animals; Calcium Channels, L-Type; Cells, Cultured; Cystic Fibrosis Transmembrane Conductance Regulator; Glycine; Heart; Hydrazines; Male; Myocytes, Cardiac; Potassium Channels, Inwardly Rectifying; Rabbits; Sodium Channels | 2011 |
Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101.
Topics: Amino Acid Sequence; Animals; Benzoates; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Fundulidae; Glyburide; Glycine; Humans; Hydrazines; Male; Molecular Sequence Data; Squalus acanthias; Swine; Thiazolidines; Xenopus laevis | 2012 |
CFTR channel pharmacology: insight from a flock of clones. Focus on "Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101".
Topics: Animals; Benzoates; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Glyburide; Glycine; Humans; Hydrazines; Male; Thiazolidines | 2012 |
Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alanine; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Chlorocebus aethiops; COS Cells; Fatty Acids, Unsaturated; Glycine; HEK293 Cells; Humans; Hydrazines; Microscopy, Fluorescence; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutant Proteins; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Structure, Secondary; Radioligand Assay; Receptors, Thromboxane A2, Prostaglandin H2; Structure-Activity Relationship; Temperature | 2012 |
Locating a plausible binding site for an open-channel blocker, GlyH-101, in the pore of the cystic fibrosis transmembrane conductance regulator.
Topics: Alanine; Animals; Binding Sites; Chloride Channels; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Glycine; Hydrazines; Oocytes; Xenopus laevis | 2012 |
Small-molecule inhibitors of the cystic fibrosis transmembrane conductance regulator increase pancreatic endocrine cell development in rat and mouse.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Glyburide; Glycine; Hydrazines; Immunochemistry; Mice; Nerve Tissue Proteins; Organ Culture Techniques; Pancreas; Pregnancy; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction | 2013 |
Protein phosphatase 1 coordinates CFTR-dependent airway epithelial HCO3- secretion by reciprocal regulation of apical and basolateral membrane Cl(-)-HCO3- exchangers.
Topics: Bicarbonates; Cell Line, Tumor; Cell Membrane; Chloride-Bicarbonate Antiporters; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Glycine; Humans; Hydrazines; Membrane Transport Proteins; Okadaic Acid; Polyenes; Protein Phosphatase 1; Pyrones; Respiratory System; Sulfate Transporters | 2013 |
In vitro evaluation of (99m)Tc-EDDA/tricine-HYNIC-Q-Litorin in gastrin-releasing peptide receptor positive tumor cell lines.
Topics: Animals; Bombesin; Cell Line, Tumor; Cysteine; Edetic Acid; Glycine; Humans; Hydrazines; Ligands; Mice; Niacinamide; Oligopeptides; Organotechnetium Compounds; Radiopharmaceuticals; Rats; Receptors, Bombesin | 2013 |
Protection against oxidative stress in beta thalassemia/hemoglobin E erythrocytes by inhibitors of glutathione efflux transporters.
Topics: Adolescent; Antioxidants; beta-Thalassemia; Child; Erythrocytes; Female; Glutathione; Glycine; Hemoglobin E; Humans; Hydrazines; Male; Membrane Transport Proteins; Osmotic Pressure; Oxidative Stress; Propionates; Quinolines; Reactive Oxygen Species; Young Adult | 2013 |
Ligand-based receptor identification on living cells and tissues using TRICEPS.
Topics: Biotin; ErbB Receptors; Glycine; Glycosylation; Humans; Hydrazines; Ligands; Mass Spectrometry; Molecular Biology; Peptides; Protein Structure, Tertiary; Receptor, ErbB-2; Receptors, Cell Surface; Succinimides | 2013 |
An improved radiolabelled RNA aptamer molecule for HER2 imaging in cancers.
Topics: Animals; Aptamers, Nucleotide; Cell Line, Tumor; Female; Glycine; Humans; Hydrazines; Indicators and Reagents; Ligands; Mice; Mice, Nude; Molecular Imaging; Niacinamide; Ovarian Neoplasms; Radiopharmaceuticals; Receptor, ErbB-2; RNA; Technetium; Tissue Distribution | 2014 |
Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na.
Topics: Acridones; Antimitotic Agents; Cell Cycle Checkpoints; Cell Cycle Proteins; Centrosome; Drug Screening Assays, Antitumor; Glycine; HeLa Cells; High-Throughput Screening Assays; Humans; Hydrazines; Microtubules; Mitosis; Molecular Structure; Molecular Weight; Phosphoinositide-3 Kinase Inhibitors; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Sulfones | 2014 |
Revisiting CFTR inhibition: a comparative study of CFTRinh -172 and GlyH-101 inhibitors.
Topics: Animals; Benzoates; Cell Line; Cell Survival; Chlorides; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Glycine; Hydrazines; Mice; Thiazolidines | 2014 |
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.
Topics: Animals; Anoctamin-1; Calcium; Calcium Channels; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocytosis; Glucagon-Like Peptide 1; Glycine; Humans; Hydrazines; Insulin-Secreting Cells; Insulins; Ion Channels; Mice; Neoplasm Proteins; Patch-Clamp Techniques | 2014 |
Evaluation of tricine and EDDA as Co-ligands for 99mTc-labeled HYNIC-MSH analogs for melanoma imaging.
Topics: alpha-MSH; Animals; Chelating Agents; Diagnostic Imaging; Edetic Acid; Glycine; Hydrazines; Ligands; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nicotinic Acids; Organotechnetium Compounds; Peptides; Protein Binding; Radiopharmaceuticals; Tissue Distribution | 2015 |
Pulmonary surfactant in the airway physiology: a direct relaxing effect on the smooth muscle.
Topics: Animals; Biological Products; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Glycine; Guinea Pigs; Humans; Hydrazines; KATP Channels; Lung; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phospholipids; Pulmonary Surfactants; Tissue Culture Techniques; Trachea | 2015 |
Murine and human CFTR exhibit different sensitivities to CFTR potentiators.
Topics: Aminophenols; Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Glycine; Humans; Hydrazines; Mice; Oocytes; Quinolones; Species Specificity; Xenopus laevis | 2015 |
Mechanosensitive activation of CFTR by increased cell volume and hydrostatic pressure but not shear stress.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Size; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Female; Glycine; Humans; Hydrazines; Hydrostatic Pressure; Ion Channel Gating; Lung; Membrane Potentials; Mutation; Oocytes; Patch-Clamp Techniques; Shear Strength; Stress, Mechanical; Xenopus laevis | 2015 |
Potentiators exert distinct effects on human, murine, and Xenopus CFTR.
Topics: Amino Acid Sequence; Aminophenols; Animals; Cells, Cultured; Chloride Channel Agonists; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Evaluation, Preclinical; Glycine; Hydrazines; Membrane Potentials; Mice; Nitrobenzoates; Patch-Clamp Techniques; Quinolones; Sequence Deletion; Xenopus laevis | 2016 |
CFTR modulates RPS27 gene expression using chloride anion as signaling effector.
Topics: Anthracenes; Autocrine Communication; Benzoates; Cell Line, Tumor; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Fluorescent Dyes; Gene Expression Regulation; Glycine; Humans; Hydrazines; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Ion Transport; MAP Kinase Kinase 4; Metalloproteins; Nuclear Proteins; Protein Kinase Inhibitors; Ribosomal Proteins; RNA-Binding Proteins; Signal Transduction; Thiazolidines | 2017 |
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Female; Glycine; Humans; Hydrazines; MCF-7 Cells; Mice, Nude; Niacinamide; Oligopeptides; Radionuclide Imaging; Radiopharmaceuticals; Technetium | 2018 |
CFTR rescue with VX-809 and VX-770 favors the repair of primary airway epithelial cell cultures from patients with class II mutations in the presence of Pseudomonas aeruginosa exoproducts.
Topics: Aminophenols; Aminopyridines; Benzodioxoles; Cells, Cultured; Chloride Channel Agonists; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Combinations; Exotoxins; Glycine; Humans; Hydrazines; Mutation; Pseudomonas aeruginosa; Quinolones; Regeneration; Respiratory Mucosa | 2018 |
Preliminary application of micro-SPECT/CT imaging by
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Edetic Acid; Glycine; Humans; Hydrazines; Lung Neoplasms; Male; Mice; Mice, Nude; Nicotinic Acids; Organotechnetium Compounds; Proto-Oncogene Proteins c-met; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous | 2019 |
Sterics and Stereoelectronics in Aza-Glycine: Impact of Aza-Glycine Preorganization in Triple Helical Collagen.
Topics: Collagen; Glycine; Hydrazines; Hydrogen Bonding; Models, Molecular; Protein Conformation; Protein Stability | 2019 |
Increasing Sphingolipid Synthesis Alleviates Airway Hyperreactivity.
Topics: Alveolar Epithelial Cells; Bradykinin; Bronchial Hyperreactivity; Calcium; Calcium Signaling; Fenretinide; Glycine; Humans; Hydrazines; Metabolome; Methacholine Chloride; Muscle Contraction; Serine C-Palmitoyltransferase; Sphingolipids | 2020 |
Epithelial barrier function properties of the 16HBE14o- human bronchial epithelial cell culture model.
Topics: Bronchi; Cell Culture Techniques; Cell Differentiation; Cell Line; Cell Membrane Permeability; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Impedance; Epithelial Cells; Glycine; Humans; Hydrazines; Mannitol; Respiratory Mucosa; Respiratory Tract Diseases; Tight Junctions | 2020 |
Biosynthesis of triacsin featuring an N-hydroxytriazene pharmacophore.
Topics: Biocatalysis; Coenzyme A Ligases; Escherichia coli; Glycine; Hydrazines; Lipid Metabolism; Lipids; Nitrites; Streptomyces aureofaciens; Triazenes | 2021 |
CFTR limits F-actin formation and promotes morphological alignment with flow in human lung microvascular endothelial cells.
Topics: Actin Cytoskeleton; Actins; Cystic Fibrosis Transmembrane Conductance Regulator; Endothelial Cells; Endothelin-1; Glycine; Humans; Hydrazines; Lung; Nitrites; Stress, Mechanical; Tumor Necrosis Factor-alpha | 2021 |