Compounds > hoe 166
Page last updated: 2024-09-05

hoe 166 and isradipine

hoe 166 has been researched along with isradipine in 4 studies

Compound Research Comparison

Studies
(hoe 166)		Trials
(hoe 166)		Recent Studies (post-2010)
(hoe 166)		Studies
(isradipine)		Trials
(isradipine)		Recent Studies (post-2010) (isradipine)
6001,40334686

Protein Interaction Comparison

ProteinTaxonomyhoe 166 (IC50)isradipine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1COryctolagus cuniculus (rabbit)0.107
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)0.221
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0022

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glossmann, H; Grassegger, A; Knaus, HG; Striessnig, J; Weiler, M1
Becker, R; Glossmann, H; Grabner, M; Henning, R; Kaiser, J; Knaus, HG; Linz, W; Meusburger, E; Schölkens, B; Striessnig, J1
Garcia, L; Lazdunski, M; Rieger, F; Romey, G1
Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H1

Other Studies

4 other study(ies) available for hoe 166 and isradipine

ArticleYear
[3H]HOE166 defines a novel calcium antagonist drug receptor--distinct from the 1,4 dihydropyridine binding domain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:6 Pt 2

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Drosophila; Guinea Pigs; In Vitro Techniques; Isradipine; Kinetics; Membranes; Muscles; Oxadiazoles; Piperidines; Proteins; Receptors, Nicotinic; Thiazines

1989
Evidence for a distinct Ca2+ antagonist receptor for the novel benzothiazinone compound HOE 166.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:3

    Topics: Action Potentials; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Guinea Pigs; Heart; Hippocampus; In Vitro Techniques; Isradipine; Muscle Contraction; Muscle, Smooth; Muscles; Myocardial Contraction; Myocardium; Oxadiazoles; Papillary Muscles; Piperidines; Rabbits; Receptors, Nicotinic; Splanchnic Circulation; Strophanthins; Thiazines

1988
Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling.
    Biochemical and biophysical research communications, 1988, Nov-15, Volume: 156, Issue:3

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Evoked Potentials; Isradipine; Mice; Muscle Contraction; Oxadiazoles; Piperidines; Thiazines; Verapamil

1988
A novel high affinity class of Ca2+ channel blockers.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil

1988