hedamycin has been researched along with guanine in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clement, JJ; Hansen, M; Hurley, LH; Sun, D | 1 |
| Hardman, LC; Murray, V | 1 |
| Hansen, M; Hurley, L; Yun, S | 1 |
3 other study(ies) available for hedamycin and guanine
| Article | Year |
|---|---|
Structure of the altromycin B (N7-guanine)-DNA adduct. A proposed prototypic DNA adduct structure for the pluramycin antitumor antibiotics.
Topics: Alkylation; Aminoglycosides; Anthraquinones; Anti-Bacterial Agents; Base Sequence; DNA; DNA Damage; Guanine; Hot Temperature; Intercalating Agents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Molecular Structure | 1993 |
Use of an automated sequencer to determine the sequence specificity of DNA damage.
Topics: Alkylating Agents; Anthraquinones; Automation; Base Sequence; DNA Damage; Guanine; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA | 1997 |
Hedamycin intercalates the DNA helix and, through carbohydrate-mediated recognition in the minor groove, directs N7-alkylation of guanine in the major groove in a sequence-specific manner.
Topics: Alkylation; Aminoglycosides; Anthraquinones; Anti-Bacterial Agents; Antibiotics, Antineoplastic; DNA; Guanine; Intercalating Agents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular | 1995 |