Page last updated: 2024-08-21

hadacidin and glycine

hadacidin has been researched along with glycine in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199037 (60.66)18.7374
1990's16 (26.23)18.2507
2000's3 (4.92)29.6817
2010's4 (6.56)24.3611
2020's1 (1.64)2.80

Authors

AuthorsStudies
Freese, E; Heinze, JE; Mitani, T1
Shah, RM2
Dye, FJ; Kollar, EJ1
Patterson, D1
Ladino, C; Lynch, RD; Rabito, CA; Schneeberger, EE2
Benkhaial, G; Burdett, D; Schuing, R; Shah, RM; Young, AV1
Klinger, W; Kretzschmar, M; Wagner, T; Zenk, W1
Chan, L; Cheung, C; Lai, LW; Lien, YH; Patterson, D1
Jahngen, EG; Kozwich, DL; Malliaros, DP1
Foley, JM; Harkema, SJ; Meyer, RA1
Brkljac, O; Jerance, D; Kovacević, Z2
Stiller, KJ; Zenk, W1
Möckel, M; Wagner, T; Zenk, W1
Reinhardt, J; Zenk, W1
Stiller, KJ; Wagner, T; Zenk, W1
Jahngen, EG; Rossomando, EF3
Kinsella, BA; Rossomando, EF; Thomas, HF; Whitehead, MC1
Ritter, EJ1
Bean, TL; Walker, MD; Webster, HK; Whaun, JM1
Bernlohr, DA; Switzer, RL1
Cheng, HW; Rice, A; Verham, R; Wang, AL; Wang, CC1
Dworkin, M; Shimkets, LJ1
Rooze, M1
Jahngen, EG; Rossomando, EF; Soll, DR; Varnum, B1
Crean, EV; Lagerstedt, JP; Rossomando, EF1
Meyer, RA; Terjung, RL1
Ashimine, DT; Early, RJ; Ledgerwood, KS; Lee, CN; Miller-Patrick, K; Nusser, KD; Tanaka, Y; Vincent, DL; Weems, CW; Weems, YS1
Anderson, RJ; Lee, SF; Siehl, DL; Subramanian, MV; Toschi, AG; Walters, EW1
Arabadjis, PG; Rundell, KW; Terjung, RL; Tullson, PC1
Anderson, RJ; Fromm, HJ; Honzatko, RB; Lee, SF; Poland, BW; Siehl, DL; Subramanian, MV1
Fromm, HJ; Honzatko, RB; Poland, BW1
Brkljac, O; Kovacević, Z; Oros, J1
Gundlach, KK1
Cashel, M; Fromm, HJ; Honzatko, RB; Hou, Z1
Fromm, HJ; Honzatko, RB; Hou, Z; Wang, W1
Borza, T; Fromm, HJ; Honzatko, RB; Iancu, CV1
DULANEY, EL; GITTERMAN, CO; HENDLIN, D; KACZKA, EA; WOODRUFF, HB1
GORDON, CN; SHIGEURA, HT3
SHIGEURA, HT2
WHITE, FR1
CHAUBE, S; MURPHY, ML1
HARRIS, JJ; TELLER, MN; WOOLLEY, GW; YAP-GUEVARA, E1
MEGO, JL1
BLACKWELL, MM; DIXON, GJ; SCHABEL, FM1
MONCRIEF, FC; PITTILLO, RF1
ELLISON, RR1
DULANEY, EL; FOLKERS, K; GITTERMAN, CO; KACZKA, EA1
Anand, RP; Balaram, H; Eaazhisai, K; Gayathri, P; Jayalakshmi, R; Murthy, MR; Sumathy, K1
Balaram, H; Bopanna, MP; Bulusu, V; Mehrotra, S1
Elliott, GI; Tibrewal, N1
Balaram, H; Karnawat, V; Mehrotra, S; Puranik, M1
Bubić, A; Bzowska, A; Leščić Ašler, I; Luić, M; Mrnjavac, N; Stuparević, I; Wielgus-Kutrowska, B; Łyczek, M1
Aleksić Sabo, V; Bzowska, A; Jagusztyn-Krynicka, EK; Jaźwiec, R; Kazazić, S; Knežević, P; Leščić Ašler, I; Luić, M; Wojtyś, MI1

Other Studies

61 other study(ies) available for hadacidin and glycine

ArticleYear
Induction of sporulation in Bacillus subtilis by decoyinine or hadacidin.
    Biochemical and biophysical research communications, 1977, Aug-08, Volume: 77, Issue:3

    Topics: Adenosine; Anti-Bacterial Agents; Bacillus subtilis; Cell Division; Culture Media; Formaldehyde; Glycine; Spores, Bacterial

1977
Effects of prenatal administration of hadacidin, a cancer chemotherapeutic agent, on the development of hamster fetuses.
    Journal of embryology and experimental morphology, 1977, Volume: 39

    Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Body Weight; Cleft Lip; Cleft Palate; Cricetinae; Dose-Response Relationship, Drug; Female; Fetal Resorption; Fetus; Formaldehyde; Gestational Age; Glycine; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mesocricetus; Micrognathism; Pregnancy; Teratogens

1977
Inhibition of mouse molar morphogenesis in vitro by hadacidin.
    Experimental cell biology, 1978, Volume: 46, Issue:3

    Topics: Adenine; Adenosine; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Formaldehyde; Glycine; Mice; Mitosis; Molar; Morphogenesis; Odontogenesis; Organ Culture Techniques; Teratogens; Tooth Germ

1978
Biochemical genetics of Chinese hamster cell mutants with deviant purine metabolism III. Isolation and characterization of a mutant unable to convert IMP to AMP.
    Somatic cell genetics, 1976, Volume: 2, Issue:1

    Topics: Adenine; Adenosine Monophosphate; Cell Line; Formaldehyde; Genes; Genetic Complementation Test; Glycine; Hypoxanthines; Inosine Nucleotides; Ligases; Lyases; Mutation; Succinates

1976
Inhibition of adenine nucleotide synthesis: effect on tight junction structure and function of clone 4 MDCK cells.
    European journal of cell biology, 1991, Volume: 55, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Biological Transport; Bucladesine; Cell Line; Cells, Cultured; Clone Cells; Dogs; Epithelium; Freeze Fracturing; Glycine; Mannitol; Microscopy, Electron; Sodium; Theophylline

1991
Genesis of hadacidin-induced cleft palate in hamster: morphogenesis, electron microscopy, and determination of DNA synthesis, cAMP, and enzyme acid phosphatase.
    The American journal of anatomy, 1991, Volume: 192, Issue:1

    Topics: Acid Phosphatase; Animals; Cleft Palate; Cricetinae; Cyclic AMP; DNA; Female; Fetus; Glycine; Male; Mesocricetus; Microscopy, Electron; Teratogens

1991
[The effect of hadacidin, ultraviolet irradiation of blood (UVB) and thiamine on the prenatal development of Uje:WIST rats: correlation with the hepatic activity of gamma-glutamyltranspeptidase (GGT)].
    Journal of experimental animal science, 1991, Volume: 34, Issue:5-6

    Topics: Animals; Embryonic and Fetal Development; Female; gamma-Glutamyltransferase; Glycine; Liver; Pregnancy; Rats; Thiamine; Ultraviolet Rays

1991
Role of purine synthesis on renal function: effect of adenylosuccinate synthetase inhibition.
    Contributions to nephrology, 1991, Volume: 95

    Topics: Adenylosuccinate Synthase; Animals; Glycine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kidney; Male; Perfusion; Purines; Rats; Rats, Inbred Strains

1991
Purification and characterization of developmentally regulated AMP deaminase from Dictyostelium discoideum.
    Differentiation; research in biological diversity, 1991, Volume: 46, Issue:3

    Topics: Adenosine Triphosphate; AMP Deaminase; Animals; Antibiotics, Antineoplastic; Chromatography; Cyclophosphamide; Dactinomycin; Dictyostelium; Dose-Response Relationship, Drug; Freeze Drying; Gene Expression Regulation, Enzymologic; Glycine; Guanosine Triphosphate; Molecular Weight; Phosphates; Sonication; Substrate Specificity

1991
Decreased ATP cost of isometric contractions in ATP-depleted rat fast-twitch muscle.
    The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 1

    Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Energy Metabolism; Glycine; Isometric Contraction; Magnetic Resonance Spectroscopy; Male; Muscles; Phosphorus; Rats; Rats, Inbred Strains; Time Factors

1991
Mechanism and control of degradation and resynthesis of adenylates in tumour cells.
    The Biochemical journal, 1991, Jan-15, Volume: 273(Pt 2)

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Carcinoma, Ehrlich Tumor; Glucose; Glutamine; Glycine; Hydrolysis; Inosine; Kinetics; Liver Neoplasms, Experimental; Mice; Rats; Rats, Inbred Strains; Rotenone; Tumor Cells, Cultured

1991
[Proliferative activity of mesenchyme and epithelium in teratogen- affected palatogenesis].
    Acta histochemica. Supplementband, 1990, Volume: 39

    Topics: Animals; Cell Division; DNA Replication; Epithelial Cells; Epithelium; Female; Glycine; Mesoderm; Palate; Pregnancy; Rats; Rats, Inbred Strains; Reference Values; Teratogens; Thymidine; Tritium

1990
Reduction of adenine nucleotide content of clone 4 MDCK cells: effects on multiplication, protein synthesis, and morphology.
    Journal of cellular physiology, 1989, Volume: 140, Issue:1

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Cell Count; Cell Division; Cell Line; Clone Cells; Cyclic AMP; Glycine; Protein Biosynthesis; Time Factors

1989
[Teratogen-modified palatogenesis in the Uje: WIST rat. 2. The effect of thiamine on the incidence of cheilognathopalatoschisis].
    Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, 1987, Volume: 75, Issue:6

    Topics: Animals; Cleft Lip; Cleft Palate; Disease Models, Animal; Female; Glycine; Maxilla; Palate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Teratogens; Thiamine

1987
[Teratogenically modified palatogenesis in Uje: WIST rats. 1. The lactate and pyruvate picture of whole blood and amniotic fluid].
    Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, 1987, Volume: 75, Issue:5

    Topics: Amniotic Fluid; Animals; Cleft Palate; Female; Glycine; Lactates; Palate; Pregnancy; Pyruvates; Rats; Rats, Inbred Strains; Teratogens; Time Factors

1987
[Teratogenically modified palatogenesis in the Uje:WIST rat. 3. Proliferative activity in the mesenchyme and epithelium of the palatine process].
    Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, 1987, Volume: 75, Issue:8

    Topics: Animals; Cell Division; Epithelial Cells; Epithelium; Gestational Age; Glycine; Mesoderm; Palate; Rats; Rats, Inbred Strains

1987
AMP deaminase in Dictyostelium discoideum: increase in activity following nutrient deprivation induced by starvation or hadacidin.
    Molecular and cellular biochemistry, 1986, Volume: 71, Issue:1

    Topics: Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Cell Division; Culture Media; Dictyostelium; Enzyme Activation; Formycins; Glycine; Guanosine Monophosphate; Hypoxanthine Phosphoribosyltransferase; Nucleotide Deaminases; Ribonucleotides; Substrate Specificity

1986
Cellular reactions during drug-induced cleft palate.
    Journal of craniofacial genetics and developmental biology. Supplement, 1986, Volume: 2

    Topics: Acid Phosphatase; Animals; Cleft Palate; Cricetinae; Cyclic AMP; Female; Fluorouracil; Gestational Age; Glycine; Hydrocortisone; Palate, Soft; Pregnancy; Teratogens

1986
The role of glutamine oxidation and the purine nucleotide cycle for adaptation of tumour energetics to the transition from the anaerobic to the aerobic state.
    The Biochemical journal, 1988, Jun-01, Volume: 252, Issue:2

    Topics: Adenine Nucleotides; Aerobiosis; Anaerobiosis; Animals; Carcinoma, Ehrlich Tumor; Deoxyglucose; Energy Metabolism; Glutamine; Glycine; Inosine; Purine Nucleotides; Rotenone; Tumor Cells, Cultured

1988
Effect of the amino acid analog hadacidin on intracellular membrane flow and the cell surface in Dictyostelium discoideum. A transmission- and scanning-electron-microscope study.
    Differentiation; research in biological diversity, 1986, Volume: 31, Issue:2

    Topics: Cell Membrane; Dictyostelium; Glycine; Membrane Fluidity; Microscopy, Electron; Microscopy, Electron, Scanning

1986
Potentiation of teratogenesis.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:3 Pt 1

    Topics: Animals; Antibiotics, Antineoplastic; Cytarabine; DNA; Drug Synergism; Embryo, Mammalian; Female; Floxuridine; Gestational Age; Glycine; Hydroxyurea; Pregnancy; Purines; Rats; Rats, Inbred Strains; Teratogens

1984
Synthesis of adenosine nucleotides from hypoxanthine by human malaria parasites (Plasmodium falciparum) in continuous erythrocyte culture: inhibition by hadacidin but not alanosine.
    Biochemical pharmacology, 1984, May-01, Volume: 33, Issue:9

    Topics: Adenosine Triphosphate; Adenylosuccinate Synthase; Alanine; Animals; Erythrocytes; Glycine; Humans; Hypoxanthines; Plasmodium falciparum; Purine Nucleotides

1984
Regulation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase inactivation in vivo.
    Journal of bacteriology, 1983, Volume: 153, Issue:2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Amidophosphoribosyltransferase; Ammonia; Bacillus subtilis; Glucose; Glycine; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Pentosyltransferases

1983
Differential effects of inhibitors of purine metabolism on two trichomonad species.
    Biochemical pharmacology, 1984, Apr-15, Volume: 33, Issue:8

    Topics: Alanine; Animals; Chromatography, High Pressure Liquid; Formycins; Glycine; Mycophenolic Acid; Purine Nucleotides; Purines; Pyrimidine Nucleosides; Species Specificity; Toyocamycin; Trichomonas vaginalis; Tritrichomonas; Tubercidin; Vidarabine

1984
Adenylosuccinate synthetase from Dictyostelium discoideum: effects of hadacidin analogs and binding of [14C]hadacidin.
    Archives of biochemistry and biophysics, 1984, Feb-15, Volume: 229, Issue:1

    Topics: Adenylosuccinate Synthase; Aspartic Acid; Chromatography; Dictyostelium; Glycine; Ligases; Substrate Specificity

1984
Excreted adenosine is a cell density signal for the initiation of fruiting body formation in Myxococcus xanthus.
    Developmental biology, 1981, Volume: 84, Issue:1

    Topics: Adenosine; Carbon; Cell Count; Cell Division; Formaldehyde; Glycine; Myxococcales; Nucleotides; Purines

1981
Correlations between necrotic patterns and limb skeletal defects induced by antimitotic drugs in the mouse.
    Progress in clinical and biological research, 1983, Volume: 110 Pt A

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Cell Survival; Cytarabine; Cytidine Monophosphate; Ectoderm; Extremities; Female; Glycine; Hyperplasia; Limb Deformities, Congenital; Mesoderm; Mice; Mitosis; Necrosis; Pregnancy; Time Factors

1983
Permeability of Dictyostelium discoideum to fucose and uracil following growth-arrest induced by starvation, hadacidin, and cerulenin.
    Differentiation; research in biological diversity, 1982, Volume: 23, Issue:1

    Topics: Antifungal Agents; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cerulenin; Dictyostelium; Fucose; Glycine; Pinocytosis; Starvation; Uracil

1982
Inhibition of a nutrient-dependent pinocytosis in Dictyostelium discoideum by the amino acid analogue hadacidin.
    The Journal of cell biology, 1981, Volume: 91, Issue:1

    Topics: Antibiotics, Antineoplastic; Cell Division; Culture Media; Dictyostelium; Formaldehyde; Glucose; Glycine; Morphogenesis; Pinocytosis

1981
Lysosomal abnormalities in hadacidin-treated Dictyostelium discoideum amoebae.
    Journal of general microbiology, 1981, Volume: 123, Issue:2

    Topics: Dictyostelium; Formaldehyde; Glycine; Lysosomes; Sucrose

1981
AMP deamination and IMP reamination in working skeletal muscle.
    The American journal of physiology, 1980, Volume: 239, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; Animals; Formaldehyde; Glycine; Inosine Monophosphate; Inosine Nucleotides; Lactates; Male; Muscle Contraction; Muscles; Phosphocreatine; Physical Exertion; Rats

1980
Effects of the purine biosynthesis pathway inhibitors azaserine, hadacidin, and mycophenolic acid on the developing ovine corpus luteum.
    The Chinese journal of physiology, 1993, Volume: 36, Issue:4

    Topics: Adenosine Monophosphate; Animals; Antibiotics, Antineoplastic; Azaserine; Chromatography, High Pressure Liquid; Corpus Luteum; Estrus; Female; Glycine; Guanosine Monophosphate; Inosine Monophosphate; Mycophenolic Acid; Pregnancy; Progesterone; Purines; Radioimmunoassay; Sheep

1993
Adenylosuccinate synthetase: site of action of hydantocidin, a microbial phytotoxin.
    Plant physiology, 1996, Volume: 110, Issue:3

    Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Adenylosuccinate Synthase; Antidotes; Arabidopsis; Enzyme Inhibitors; Glycine; Herbicides; Hydantoins; Inosine Monophosphate; Pentosephosphates; Zea mays

1996
IMP reamination to AMP in rat skeletal muscle fiber types.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 1

    Topics: Adenosine Monophosphate; Amines; Animals; Blood; Electric Stimulation; Glycine; Inosine Monophosphate; Male; Motor Activity; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

1996
Refined crystal structure of adenylosuccinate synthetase from Escherichia coli complexed with hydantocidin 5'-phosphate, GDP, HPO4(2-), Mg2+, and hadacidin.
    Biochemistry, 1996, Dec-10, Volume: 35, Issue:49

    Topics: Adenylosuccinate Synthase; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli; Glycine; Guanosine Diphosphate; Herbicides; Hydantoins; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Structure; Phosphates

1996
Crystal structures of adenylosuccinate synthetase from Escherichia coli complexed with GDP, IMP hadacidin, NO3-, and Mg2+.
    Journal of molecular biology, 1996, Dec-20, Volume: 264, Issue:5

    Topics: Adenylosuccinate Synthase; Binding Sites; Crystallography, X-Ray; Electrochemistry; Escherichia coli; Glycine; Guanosine Diphosphate; Inosine Monophosphate; Magnesium; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nitrates; Protein Conformation

1996
Oxidation of glutamine in cancer cells and regeneration of adenylates via adenylosuccinate synthetase.
    Contributions to nephrology, 1997, Volume: 121

    Topics: Adenine Nucleotides; Adenylosuccinate Synthase; Anaerobiosis; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Cell Hypoxia; Glutamine; Glycine; Inosine; Inosine Monophosphate; Mice; Oxidation-Reduction; Oxidative Stress; Oxygen

1997
Malformations of the temporo-mandibular joint in laboratory animals and in man.
    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 1999, Volume: 181, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Female; Glycine; Humans; Hydroxamic Acids; Infant, Newborn; Mercaptopurine; Methylnitrosourea; Mice; Mice, Inbred Strains; Pregnancy; Procarbazine; Rats; Rats, Sprague-Dawley; Temporomandibular Joint; Teratogens

1999
Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.
    The Journal of biological chemistry, 1999, Jun-18, Volume: 274, Issue:25

    Topics: Adenosine Monophosphate; Adenylosuccinate Synthase; Binding Sites; Chromatography, Thin Layer; Enzyme Inhibitors; Escherichia coli; Glycine; Guanosine Tetraphosphate; Ligands; Magnesium; Models, Molecular; Molecular Sequence Data; Molecular Structure

1999
IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
    The Journal of biological chemistry, 2002, Feb-22, Volume: 277, Issue:8

    Topics: Adenylosuccinate Synthase; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Glycine; Guanosine Triphosphate; Inosine Monophosphate; Models, Molecular; Protein Conformation

2002
IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase.
    The Journal of biological chemistry, 2002, Jul-26, Volume: 277, Issue:30

    Topics: Adenylosuccinate Synthase; Animals; Binding Sites; Catalysis; Glycine; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Inosine Monophosphate; Ligands; Mice; Models, Molecular; Muscles; Protein Conformation; Recombinant Proteins

2002
The human tumor-egg host system. II. Discovery and properties of a new antitumor agent, hadacidin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 109

    Topics: Antineoplastic Agents; Glycine; Humans; Neoplasms

1962
Hadacidin, a new inhibitor of purine biosynthesis.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Antimetabolites; Antineoplastic Agents; Glycine; Purines

1962
The mechanism of action of hadacidin.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Antimetabolites; Antineoplastic Agents; Fabaceae; Glycine; Humans; Purines

1962
6-Azauracil inhibition of Escherichia coli B and its reversal by hadacidin.
    Archives of biochemistry and biophysics, 1963, Volume: 100

    Topics: Antineoplastic Agents; Escherichia coli; Glycine; Uracil

1963
Further studies on the activity of hadacidin.
    Cancer research, 1962, Volume: 22

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Escherichia coli; Glycine; Proteins

1962
Hadacidin.
    Cancer chemotherapy reports, 1962, Volume: 23

    Topics: Amino Acids; Antineoplastic Agents; Glycine

1962
Teratogenic effect of Hadacidin (a new growth inhibitory chemical) on the rat fetus.
    The Journal of experimental zoology, 1963, Volume: 152

    Topics: Animals; Antineoplastic Agents; Congenital Abnormalities; Fetus; Glycine; Neoplasms; Rats

1963
Effects of hadacidin on human tumors grown in eggs and rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 110

    Topics: Animals; Antineoplastic Agents; Glycine; Neoplasms; Neoplasms, Experimental; Rats

1962
STRUCTURAL MODIFICATIONS OF HADACIDIN AND THEIR EFFECTS ON THE ACTIVITY OF ADENYLOSUCCINATE SYNTHETASE.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Adenylosuccinate Synthase; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Antineoplastic Agents; Enzyme Inhibitors; Glycine; Ligases; Propionates; Research

1963
THE EFFECT OF HADACIDIN ON CHLOROPLAST DEVELOPMENT IN NON-DIVIDING EUGLENA CELLS.
    Biochimica et biophysica acta, 1964, Mar-30, Volume: 79

    Topics: Adenine; Anti-Bacterial Agents; Aspartic Acid; Chlorophyll; Chloroplasts; Enzyme Inhibitors; Euglena; Glycine; Ligases; Light; Metabolism; Pharmacology; Research; Tissue Culture Techniques

1964
HADACIDIN POTENTIATION OF LETHAL ACTION OF IONIZING IRRADIATION. I. EFFECT OF MAMMALIAN TUMOR CELLS IN CULTURE.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Glycine; Pharmacology; Radiation Effects; Research; Tissue Culture Techniques

1965
HADACIDIN POTENTIATION OF LETHAL ACTION OF IONIZING IRRADIATION. II. EFFECT ON PROLIFERATING GRAM-NEGATIVE BACTERIA.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Escherichia coli; Glycine; Gram-Negative Bacteria; Pharmacology; Radiation Effects; Research; Salmonella typhimurium; Serratia marcescens

1965
CLINICAL PHARMACOLOGIC STUDY OF HADACIDIN (NSC-521778).
    Cancer chemotherapy reports, 1965, Volume: 46

    Topics: Antineoplastic Agents; Biomedical Research; Drug Therapy; Glycine; Toxicology

1965
Hadacidin, a new growth-inhibitory substance in human tumor systems.
    Biochemistry, 1962, Volume: 1

    Topics: Antineoplastic Agents; Glycine; Humans; Neoplasms

1962
Crystal structure of fully ligated adenylosuccinate synthetase from Plasmodium falciparum.
    Journal of molecular biology, 2004, Jan-30, Volume: 335, Issue:5

    Topics: Adenylosuccinate Synthase; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Glycine; Guanosine Diphosphate; Hydrogen Bonding; Inosine Monophosphate; Magnesium; Models, Molecular; Molecular Sequence Data; Molecular Structure; Plasmodium falciparum; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid

2004
Adenine metabolism in Plasmodium falciparum.
    Experimental parasitology, 2010, Volume: 125, Issue:2

    Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine Monophosphate; Adenylosuccinate Synthase; Enzyme Inhibitors; Glycine; Hypoxanthine; Inhibitory Concentration 50; Plasmodium falciparum

2010
Evaluation of hadacidin analogues.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Adenylosuccinate Synthase; Glycine; Penicillium

2011
Exquisite Modulation of the Active Site of Methanocaldococcus jannaschii Adenylosuccinate Synthetase in Forward Reaction Complexes.
    Biochemistry, 2016, 05-03, Volume: 55, Issue:17

    Topics: Adenosine Monophosphate; Adenylosuccinate Synthase; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Glycine; Guanosine Triphosphate; Inosine Monophosphate; Kinetics; Ligands; Methanocaldococcus; Models, Molecular; Protein Conformation

2016
In the quest for new targets for pathogen eradication: the adenylosuccinate synthetase from the bacterium Helicobacter pylori.
    Journal of enzyme inhibition and medicinal chemistry, 2018, Volume: 33, Issue:1

    Topics: Adenosine Monophosphate; Adenylosuccinate Synthase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Helicobacter pylori; Molecular Structure; Structure-Activity Relationship

2018
A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori.
    Applied microbiology and biotechnology, 2021, Volume: 105, Issue:20

    Topics: Adenylosuccinate Synthase; Enzyme Inhibitors; Formycins; Glycine; Helicobacter pylori; Purine-Nucleoside Phosphorylase

2021
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