Compounds > gw420867x
Page last updated: 2024-09-04

gw420867x and emivirine

gw420867x has been researched along with emivirine in 3 studies

Compound Research Comparison

Studies
(gw420867x)		Trials
(gw420867x)		Recent Studies (post-2010)
(gw420867x)		Studies
(emivirine)		Trials
(emivirine)		Recent Studies (post-2010) (emivirine)
17525516

Protein Interaction Comparison

ProteinTaxonomygw420867x (IC50)emivirine (IC50)
Chain A, Hiv-1 Reverse TranscriptaseHuman immunodeficiency virus 10.008
Chain A, HIV-1 REVERSE TRANSCRIPTASEHuman immunodeficiency virus 10.008
Chain B, HIV-1 REVERSE TRANSCRIPTASEHuman immunodeficiency virus 10.008
Gag-Pol polyproteinHIV-1 M:B_HXB2R0.04
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.3142

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK1
Duval, X1
Balzarini, J; Burt, V; Carbonez, A; De Clercq, E; Kleim, JP1

Other Studies

3 other study(ies) available for gw420867x and emivirine

ArticleYear
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations.
    Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

    Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2002
[The 39th ICAAC (San Francisco) and the 7th European Conference on Clinical Aspects and Treatment of HIV-infection (Lisbon). HIV infection: antiretroviral agents in the development and trial stage].
    Presse medicale (Paris, France : 1983), 2000, Feb-12, Volume: 29, Issue:5

    Topics: Alkynes; Animals; Anti-HIV Agents; Antiviral Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Time Factors; Uracil; Viral Load

2000
Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors.
    AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6

    Topics: Alkynes; Anilides; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Nevirapine; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Thioamides; Uracil

2000