guaiacol has been researched along with lignans in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.03) | 18.7374 |
| 1990's | 10 (15.15) | 18.2507 |
| 2000's | 24 (36.36) | 29.6817 |
| 2010's | 29 (43.94) | 24.3611 |
| 2020's | 1 (1.52) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, MN; Han, GQ; Hwang, SB | 1 |
| Barth, J; Steinmann, D; Wozel, G | 1 |
| Chang, H; Cheng, HT | 1 |
| Teng, CM; Wu, TS; Yu, SM | 1 |
| Ko, FN; Lee, JY; Teng, CM; Wu, TS; Yu, SM | 1 |
| Hirose, M; Ito, N; Kimura, J; Shirai, T; Takaba, K; Yoshida, Y | 1 |
| Chamone, DA; D'Amico, EA; Fries, DM; Monteiro, HP; Neiva, TJ | 1 |
| Alali, F; Asuzu, IU; Hopp, DC; McLaughlin, JL; Njoku, CJ | 1 |
| Lee, DK; Park, S; Yang, CH | 1 |
| Kameoka, H; Kasahara, H; Miyazawa, M; Nakamura, S; Okuno, Y; Oshiro, K; Shimamura, H | 1 |
| Brown, PJ; Fenical, W; Hay, ME; Kubanek, J; Lindquist, N | 1 |
| Rajasekhar, D; Subbaraju, GV | 1 |
| Cheng, YW; Hsiao, G; Lam, KK; Lee, YM; Sheu, JR; Teng, CM; Wu, TS; Yen, MH | 1 |
| Chen, N; Pan, XF; Wu, AX; Zhao, YR | 1 |
| Chulia, AJ; Duroux, JL; Filleur, F; Le Bail, JC; Simon, A | 1 |
| Duan, H; Momota, H; Ohmoto, Y; Takaishi, Y; Taki, T | 1 |
| Azebaze, AG; Conrad, J; Fomum, ZT; Kraus, W; Ngando, TM; Nkengfack, AE; Van Heerden, FR; Vardamides, JC; Vogler, B | 1 |
| GRIEPENTROG, F | 1 |
| Chen, WS; Gu, ZB; Li, TZ; Liu, WY; Zhang, WD; Zhou, J | 1 |
| Kim, SG; Kim, YC; Ma, CJ; Park, EY; Shin, SM | 1 |
| Chang, GL; Chen, HY; Chen, TY; Hsu, YS; Hu, YL; Lee, EJ; Lee, MY; Wu, TS | 1 |
| Kim, J; Kim, SR; Kim, YC; Ma, CJ | 1 |
| Chung, JH; Moon, HI | 1 |
| Kim, YC; Lee, MK; Ma, CJ | 1 |
| Karonen, M; Liimatainen, J; Pihlaja, K; Sinkkonen, J | 1 |
| Ahn, JS; Jang, JP; Kim, BY; Kim, KA; Na, MK; Oh, WK; Sung, NJ; Yang, S | 1 |
| Jung, JC; Moon, H; Moon, HI | 1 |
| Chen, YG; Fang, A; Hai, LN; Halaweish, F; Liao, XR; Lv, YP; Song, XP | 1 |
| Daley, BJ; Enderson, BL; Gillis, RC; Karlstad, MD; Kestler, DP | 1 |
| Cho, JY; Cho, KY; Choi, GJ; Jang, KS; Kim, JC; Lee, SO; Lim, HK; Son, SW; Sung, ND | 1 |
| Chang, GJ; Chen, WP; Kuo, CM; Su, MJ; Wu, TS | 1 |
| Chang, HW; Haa, K; Hong, TG; Hwang, NK; Kim, DH; Kim, JC; Kim, JH; Moon, TC; Seo, CS; Son, JK | 1 |
| Akiyama, J; Akiyama, K; Kawaguchi, Y; Kishida, T; Maruyama, M; Masuda, T; Ohuchi, M; Someya, T; Sugahara, T; Tominaga, S; Yamauchi, S; Yamawaki, M | 1 |
| Avery, VM; Barnes, EC; Davis, RA; Healy, PC; Longden, J | 1 |
| Chen, HY; Chen, TY; Chen, YH; Chuang, IC; Hung, YC; Lee, EJ; Lee, MY; Wu, TS; Yu, SC | 1 |
| Akiyama, K; Kawaguchi, Y; Kishida, T; Koba, Y; Maruyama, M; Masuda, K; Nishiwaki, H; Sugahara, T; Yamauchi, S | 1 |
| Chen, TY; Huang, CC; Huang, SY; Lee, AC; Lee, EJ; Tai, SH; Wu, TS | 1 |
| Chen, HS; Peng, ZG; Xiao, PG; Xu, LJ; Ye, WC | 1 |
| Bhardwaj, A | 1 |
| Akamatsu, M; Hasebe, A; Kawaguchi, Y; Nishiwaki, H; Shuto, Y; Yamauchi, S | 1 |
| Hwang, JK; Kim, D; Kim, KJ; Lee, KE; Lee, MS | 1 |
| Chen, CY; Cheng, MJ; Wang, CJ; Yeh, YT | 1 |
| Hsiao, G; Hsieh, MS; Jayakumar, T; Lin, KH; Lu, YC; Sheu, JR; Wu, TS | 1 |
| Fan, MM; Feng, YL; Li, ZF; Luo, XJ; Wang, Q; Yang, SL | 1 |
| Hasebe, A; Nishiwaki, H; Shuto, Y; Wukirsari, T; Yamauchi, S | 1 |
| Amorati, R; Daquino, C; Spatafora, C; Tringali, C | 1 |
| Akiyama, K; Hasebe, A; Kishida, T; Nishiwaki, H; Sugahara, T; Yamauchi, S | 1 |
| Akiyama, K; Kishida, T; Nishi, K; Nishiwaki, H; Sugahara, T; Wukirsari, T; Yamauchi, S | 1 |
| Choi, YJ; Je, YT; Lee, BH; Lee, KY; Park, HJ; Park, S; Park, SJ; Shin, KJ; Sim, WC; Sung, SH; Yin, HQ | 1 |
| Kim, EC; Kim, TJ; Kim, WJ; Song, MC | 1 |
| Balderas-Rentería, I; Clemente-Soto, AF; del Rayo Camacho-Corona, M; Garza-González, E; Rivera, G; Segura-Cabrera, A | 1 |
| He, QX; Liu, HT; Liu, KC; Qi, YD; Wang, ZM; Xiao, PG; Zhang, BG; Zhang, J | 1 |
| Jeon, JS; Kim, SK; Kim, YM; Lee, BH; Lee, JY; Oh, SJ; Ryu, CS | 1 |
| Kishida, T; Nishi, K; Nishiwaki, H; Shuto, Y; Sugahara, T; Tabara, Y; Yamauchi, S | 1 |
| Cai, Q; Du, SS; Zheng, LS | 1 |
| Chen, L; Chen, Y; Yang, G; Zhang, Y; Zhao, N | 1 |
| Choi, MS; Choi, Y; Jeon, S; Jeong, HJ; Kang, TH; Oh, ST; Shin, HM | 1 |
| Cho, ES; Kim, TI; Kwon, HJ; Seo, CS; Son, HY; Son, JK; Song, JW; Won, YS | 1 |
| Chen, L; Chen, Y; Zhan, R; Zhang, Y | 1 |
| Akiyama, K; Ano, Y; Kishida, T; Maruyama, M; Nishi, K; Nishiwaki, H; Sugahara, T; Tanimura, R; Yamauchi, S | 1 |
| Akiyama, K; Nakazaki, S; Nishiwaki, H; Yamauchi, S | 1 |
| Camacho-Corona, MDR; Favela-Hernández, JMJ; García, A; Garza-González, E; Miranda, LD; Reyes-Melo, K; Rivas-Galindo, VM; Romo-Mancillas, A; Vargas-Villarreal, J | 1 |
| Choi, KM; Hong, JT; Jeong, H; Jung, WB; Kim, GY; Lee, A; Lee, JH; Lee, MK; Roh, YS; Sung, SH; Yoo, HS | 1 |
| Gao, SM; Guo, YJ; Liu, HT; Zhang, BG | 1 |
| Brito, JR; da Costa-Silva, TA; Ferreira, EA; Lago, JHG; Tempone, AG | 1 |
| Huang, BH; Huang, SY; Hung, CC; Lee, TE; Teng, YN; Wu, IT; Wu, TS | 1 |
66 other study(ies) available for guaiacol and lignans
| Article | Year |
|---|---|
[The investigation of lignans from Sargentodoxa cuneata (Oliv) Rehd et Wils].
Topics: Chemical Phenomena; Chemistry; Guaiacol; Lignans; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Plant Extracts; Plants, Medicinal; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1986 |
Anti-inflammatory activity of croconazole, a broad-spectrum antimycotic agent, in the arachidonic acid-induced mouse ear swelling test.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Arachidonic Acid; Ear, External; Edema; Female; Guaiacol; Imidazoles; Lignans; Lipoxygenase Inhibitors; Mice; Mice, Inbred Strains | 1995 |
Reduction of reperfusion injury in rat skeletal muscle following administration of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.
Topics: Animals; Catalase; Female; Guaiacol; Hindlimb; Ischemia; Lignans; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Receptors, Thromboxane; Reperfusion Injury; Superoxide Dismutase; Thromboxane-A Synthase; Tissue Survival | 1995 |
Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Aorta; Arachidonic Acid; Bleeding Time; Blood Platelets; Bronchoconstriction; Calcium; Cyclic AMP; Female; Guaiacol; Guinea Pigs; Humans; Lignans; Male; Mice; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Receptors, Thromboxane; Sheep; Tail; Thromboxane A2; Thromboxane-A Synthase; Trachea; Vasoconstrictor Agents | 1994 |
Cinnamophilin, a novel thromboxane A2 receptor antagonist, isolated from Cinnamomum philippinense.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Female; Guaiacol; Guinea Pigs; In Vitro Techniques; Lignans; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Plants, Medicinal; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Thromboxane; Taiwan; Thromboxane A2 | 1994 |
Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model.
Topics: Aminobiphenyl Compounds; Animals; Antimutagenic Agents; Antineoplastic Agents; Antioxidants; Carcinogens; Chlorophyllides; Curcumin; Diethylnitrosamine; Guaiacol; Hydrolyzable Tannins; Lignans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Paraffin; Phytic Acid; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Aluminum induces lipid peroxidation and aggregation of human blood platelets.
Topics: Adult; Aluminum; Guaiacol; Humans; L-Lactate Dehydrogenase; Lignans; Lipid Peroxidation; Luminescent Measurements; Platelet Aggregation; Propyl Gallate; Ristocetin; Salicylates | 1997 |
Dihydroguaiaretic acid: a bioactive component of the stem bark of Pycnanthus angolensis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Caenorhabditis elegans; Decapoda; Guaiacol; Humans; Lignans; Plant Stems; Plants, Medicinal; Trees; Tumor Cells, Cultured | 1997 |
Inhibition of fos-jun-DNA complex formation by dihydroguaiaretic acid and in vitro cytotoxic effects on cancer cells.
Topics: Dimerization; Guaiacol; Humans; Lignans; Masoprocol; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Tumor Cells, Cultured | 1998 |
Suppression of the SOS-inducing activity of Trp-P-1 and aflatoxin B1 by meso-dihydroguaiaretic acid from Machilus thunbergii in the Salmonella typhimurium TA1535/pSK1002 umu test.
Topics: Aflatoxin B1; Carbolines; Chloroform; DNA Damage; Gas Chromatography-Mass Spectrometry; Guaiacol; Lauraceae; Lignans; Magnetic Resonance Spectroscopy; Mutagens; Plant Extracts; Salmonella typhimurium; SOS Response, Genetics | 1998 |
Two antifeedant lignans from the freshwater macrophyte Saururus cernuus.
Topics: Animals; Astacoidea; Feeding Behavior; Fresh Water; Guaiacol; Lignans; Magnoliopsida; Models, Molecular; Molecular Conformation; Molecular Structure | 2000 |
Synthesis of (+)-lariciresinol 3a-acetate, a lignan from Aglaia elaeagnoidea.
Topics: Furans; Guaiacol; Lignans; Lignin; Magnetic Resonance Spectroscopy; Magnoliopsida; Models, Chemical | 2000 |
Cinnamophilin as a novel antiperoxidative cytoprotectant and free radical scavenger.
Topics: Animals; Aorta; Brain; Cell Line; Cell Membrane; Cryoprotective Agents; Free Radical Scavengers; Guaiacol; Humans; In Vitro Techniques; Lignans; Lipid Peroxidation; Liver; Mitochondria, Liver; NADPH Oxidases; NADPH-Ferrihemoprotein Reductase; Neutrophils; Peroxides; Rats; Rats, Inbred SHR; Rats, Wistar; Superoxides | 2001 |
[Total synthesis of nordihydroguaiaretic acid].
Topics: Furans; Guaiacol; Lignans; Masoprocol; Molecular Structure; Plants, Medicinal | 1997 |
Antiproliferative, anti-aromatase, anti-17beta-HSD and antioxidant activities of lignans isolated from Myristica argentea.
Topics: 17-Hydroxysteroid Dehydrogenases; Antineoplastic Agents, Phytogenic; Antioxidants; Aromatase Inhibitors; Cell Division; Guaiacol; Humans; Lignans; Magnetic Resonance Spectroscopy; Myristicaceae; Plant Extracts; Tumor Cells, Cultured | 2001 |
Immunosuppressive constituents from Saussurea medusa.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Catechols; Cytokines; Guaiacol; Immunosuppressive Agents; Leukocytes, Mononuclear; Lignans; Saussurea | 2002 |
Scaphopetalone and scaphopetalumate, a lignan and a triterpene ester from Scaphopetalum thonneri.
Topics: Cameroon; Coumaric Acids; Esters; Guaiacol; Lignans; Magnetic Resonance Spectroscopy; Malvaceae; Molecular Structure; Oleanolic Acid; Plant Bark; Tetrahydronaphthalenes; Triterpenes | 2003 |
[Allergy studies with some simple chemical substances. 7. Nor-dihydroguaiaretic acid].
Topics: Guaiac; Guaiacol; Humans; Hypersensitivity; Lignans | 1961 |
[Studies on the lignans from Patrinia scabra].
Topics: Furans; Guaiacol; Lignans; Lignin; Molecular Structure; Naphthols; Patrinia; Plant Roots; Plants, Medicinal | 2003 |
meso-dihydroguaiaretic acid from Machilus thunbergii down-regulates TGF-beta1 gene expression in activated hepatic stellate cells via inhibition of AP-1 activity.
Topics: Animals; DNA Primers; Dose-Response Relationship, Drug; Down-Regulation; Guaiacol; Immunoblotting; Immunohistochemistry; Lauraceae; Lignans; Liver; Male; Phytotherapy; Plant Bark; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Cinnamophilin reduces oxidative damage and protects against transient focal cerebral ischemia in mice.
Topics: Animals; Antioxidants; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Free Radical Scavengers; Guaiacol; Infarction, Middle Cerebral Artery; Lignans; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Time Factors | 2005 |
Meso-dihydroguaiaretic acid and licarin A of Machilus thunbergii protect against glutamate-induced toxicity in primary cultures of a rat cortical cells.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Glutathione; Guaiacol; Lauraceae; Lignans; Nitric Oxide; Peroxides; Rats; Rats, Sprague-Dawley | 2005 |
Meso-dihydroguaiaretic acid from Machilus thunbergii SIEB et ZUCC., and its effects on the expression of matrix metalloproteinase-2, 9 cause by ultraviolet irradiated cultured human keratinocyte cells (HaCaT).
Topics: Cell Line; Gene Expression Regulation, Enzymologic; Glyceraldehyde-3-Phosphate Dehydrogenases; Guaiacol; Humans; Keratinocytes; Lauraceae; Lignans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nitroblue Tetrazolium; Reverse Transcriptase Polymerase Chain Reaction; RNA; Ultraviolet Rays | 2005 |
meso-Dihydroguaiaretic acid attenuates the neurotoxic effect of staurosporine in primary rat cortical cultures.
Topics: Analysis of Variance; Animals; Apoptosis; Calcium; Caspase 3; Caspases; Cells, Cultured; Cerebral Cortex; Cytochromes c; Dansyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Galactosamine; Guaiacol; Lignans; Neurons; Neurotoxins; Peroxides; Rats; Rats, Sprague-Dawley; Staurosporine | 2006 |
Lignans from the bark extract of Pinus sylvestris L.
Topics: 4-Butyrolactone; Acetone; Benzofurans; Guaiacol; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Pinus sylvestris; Plant Extracts; Propylene Glycols; Spectrometry, Mass, Electrospray Ionization; Water | 2006 |
Inhibition of protein tyrosine phosphatase 1B by lignans from Myristica fragrans.
Topics: Animals; Cell Line; Chemical Fractionation; Enzyme Inhibitors; Granulocytes; Guaiacol; Inhibitory Concentration 50; Lignans; Mice; Myristica; Phosphorylation; Plant Extracts; Pollen; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Receptor, Insulin | 2006 |
Effect of meso-dihydroguaiaretic acid from Machilus thunbergii Sieb et Zucc on MMP-1 expression in heat shock-induced cultured primary human fibroblasts.
Topics: Cell Proliferation; Cells, Cultured; Fibroblasts; Guaiacol; Heat-Shock Response; Hot Temperature; Humans; Lauraceae; Lignans; Matrix Metalloproteinase 1; Plant Extracts | 2006 |
Compounds with DNA cleaving activity from Kadsura ananosma.
Topics: Cell Line, Tumor; Chalcones; DNA; DNA, Superhelical; Guaiacol; HeLa Cells; Humans; Kadsura; Leukemia; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nucleic Acid Conformation; Plant Bark; Plant Stems | 2006 |
Regulation of apoptosis in eicosapentaenoic acid-treated HL-60 cells.
Topics: Apoptosis; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cyclooxygenase Inhibitors; Eicosapentaenoic Acid; Enzyme Inhibitors; Fatty Acids, Unsaturated; Flavanones; Guaiacol; HL-60 Cells; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indoles; Leukotriene B4; Lignans; Lipoxygenase Inhibitors; Neutrophils; Respiratory Distress Syndrome | 2007 |
Isolation and antifungal activity of lignans from Myristica fragrans against various plant pathogenic fungi.
Topics: Antifungal Agents; Guaiacol; Lignans; Mass Spectrometry; Microbial Sensitivity Tests; Myristica; Plants; Seeds | 2007 |
Electromechanical characterization of cinnamophilin, a natural thromboxane A2 receptor antagonist with anti-arrhythmic activity, in guinea-pig heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channels, L-Type; Guaiacol; Guinea Pigs; Heart; Heart Conduction System; In Vitro Techniques; Lignans; Male; Papillary Muscles; Potassium Channels; Receptors, Thromboxane A2, Prostaglandin H2; Sodium Channels | 2008 |
Meso-dihydroguaiaretic acid isolated from Saururus chinensis inhibits cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bone Marrow Cells; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Guaiacol; Lignans; Lipoxygenase Inhibitors; Male; Mast Cells; Mice; Mice, Inbred BALB C; Saururaceae | 2008 |
Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid.
Topics: Butanes; Butylene Glycols; Free Radical Scavengers; Guaiacol; Lignans; Lipoxygenase Inhibitors; Oxidation-Reduction; Stereoisomerism | 2008 |
Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum.
Topics: Antineoplastic Agents, Phytogenic; Australia; Cell Line, Tumor; Crystallography, X-Ray; Cyclobutanes; Guaiacol; Humans; Inhibitory Concentration 50; Lauraceae; Lignans; Magnetic Resonance Spectroscopy; Plant Roots; Plants, Medicinal | 2009 |
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Guaiacol; Hippocampus; Hypoxia; Interleukin-6; Ischemic Attack, Transient; Lignans; Lipid Peroxidation; Microglia; Nitrates; Nitrites; Organ Culture Techniques; Peroxidase; Phenethylamines; Polysaccharides; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfonic Acids; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
Antimicrobial activity of stereoisomers of butane-type lignans.
Topics: Anti-Infective Agents; Bacteria; Butanes; Foodborne Diseases; Fungi; Guaiacol; Lignans; Plant Diseases; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2009 |
Cinnamophilin offers prolonged neuroprotection against gray and white matter damage and improves functional and electrophysiological outcomes after transient focal cerebral ischemia.
Topics: Animals; Antioxidants; Behavior, Animal; Body Weight; Brain; Cerebral Cortex; Confidence Intervals; Disease Models, Animal; Electrophysiology; Evoked Potentials, Somatosensory; Guaiacol; Ischemic Attack, Transient; Lignans; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuroprotective Agents; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Statistics, Nonparametric; Survival Rate | 2011 |
[Effective components against HIV-1 replicative enzymes isolated from plants].
Topics: Alkaloids; Anti-HIV Agents; Drugs, Chinese Herbal; Flavones; Guaiacol; HIV Integrase; HIV Protease; HIV Reverse Transcriptase; Lignans; Plants, Medicinal; Ranunculaceae; Rutaceae; Schisandraceae; Triterpenes | 2010 |
Experimental studies on ischemic neuroprotection: criteria for translational significance.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Disease Progression; Electrophysiology; Evoked Potentials, Somatosensory; Guaiacol; Lignans; Neuroprotective Agents; Prospective Studies; Rats; Stroke; Treatment Outcome | 2011 |
Larvicidal activity of (-)-dihydroguaiaretic acid derivatives against Culex pipiens.
Topics: Animals; Butylene Glycols; Culex; Disease Vectors; Guaiacol; Hydrophobic and Hydrophilic Interactions; Hydroxylation; Insect Control; Insecticides; Larva; Lethal Dose 50; Lignans; Stereoisomerism; Structure-Activity Relationship | 2011 |
meso-Dihydroguaiaretic acid inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Cell Culture Techniques; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Dyslipidemias; Enzyme Activation; Enzyme Inhibitors; Fatty Liver; Guaiacol; Hep G2 Cells; Humans; Hypolipidemic Agents; Insulin Resistance; Lignans; Lipid Metabolism; Liver; Molecular Targeted Therapy; Myristica; Non-alcoholic Fatty Liver Disease; Phosphorylation; Phytotherapy; Plant Extracts; Pyrazoles; Pyrimidines | 2011 |
A new 3,4-dihydronaphthalen-1(2H)-one from the leaves of Cinnamomum philippinense.
Topics: Cinnamomum; Guaiacol; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Leaves | 2012 |
Cinnamophilin isolated from Cinnamomum philippinense protects against collagen degradation in human chondrocytes.
Topics: Cell Line; Chondrocytes; Cinnamomum; Collagen; Guaiacol; Humans; I-kappa B Proteins; Interleukin-1beta; Lignans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Phosphorylation; Proto-Oncogene Proteins c-jun; Signal Transduction | 2013 |
[Chemical constituents from Coptis chinensis].
Topics: Benzodioxoles; Chloroform; Chromatography, High Pressure Liquid; Coptis; Ethanol; Guaiacol; Lignans; Molecular Structure; Quinolizines; Rhizome | 2012 |
First discovery of insecticidal activity of 9,9'-epoxylignane and dihydroguaiaretic acid against houseflies and the structure-activity relationship.
Topics: Animals; Epoxy Compounds; Guaiacol; Houseflies; Insecticides; Lignans; Plant Extracts; Stereoisomerism; Structure-Activity Relationship | 2013 |
Reaction of benzoxanthene lignans with peroxyl radicals in polar and non-polar media: cooperative behaviour of OH groups.
Topics: Caffeic Acids; Catechols; Free Radicals; Guaiacol; Lignans; Peroxides; Xanthenes | 2013 |
Quantitative structure-activity relationship analysis of antifungal (+)-dihydroguaiaretic acid using 7-phenyl derivatives.
Topics: Alternaria; Fungicides, Industrial; Guaiacol; Lignans; Quantitative Structure-Activity Relationship | 2013 |
Cytotoxic activity of dietary lignan and its derivatives: structure-cytotoxic activity relationship of dihydroguaiaretic acid.
Topics: Animals; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Cytotoxins; Guaiacol; HL-60 Cells; Humans; Lignans; Molecular Structure; Structure-Activity Relationship; Vero Cells | 2014 |
LXR-α antagonist meso-dihydroguaiaretic acid attenuates high-fat diet-induced nonalcoholic fatty liver.
Topics: Animals; Base Sequence; Cell Line, Tumor; Diet, High-Fat; DNA Primers; Fatty Liver; Guaiacol; Humans; Lignans; Lipogenesis; Liver X Receptors; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Non-alcoholic Fatty Liver Disease; Orphan Nuclear Receptors | 2014 |
Meso-dihydroguaiaretic acid inhibits rat aortic vascular smooth muscle cell proliferation by suppressing phosphorylation of platelet-derived growth factor receptor beta.
Topics: Animals; Aorta; Becaplermin; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Guaiacol; JNK Mitogen-Activated Protein Kinases; Lignans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phospholipase C gamma; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Rats; Signal Transduction | 2014 |
Potential mechanism of action of meso-dihydroguaiaretic acid on Mycobacterium tuberculosis H37Rv.
Topics: Antitubercular Agents; Binding Sites; Down-Regulation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Guaiacol; Lignans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Up-Regulation | 2014 |
[Chemical constituents of Kadsura oblongifolia and evaluation of their toxicity].
Topics: Animals; Embryo, Nonmammalian; Guaiacol; Kadsura; Lignans; Plant Extracts; Quercetin; Triterpenes; Zebrafish | 2014 |
Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice.
Topics: Animals; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Guaiacol; Half-Life; Humans; Lauraceae; Lignans; Male; Mice; Mice, Inbred ICR; Microsomes, Liver | 2015 |
Acute larvicidal activity against mosquitoes and oxygen consumption inhibitory activity of dihydroguaiaretic acid derivatives.
Topics: Animals; Culex; Guaiacol; Insecticides; Larva; Lignans; Molecular Structure; Oxygen | 2015 |
[Study on chemical constituents from Schisandra chinensis stem].
Topics: Cyclooctanes; Guaiacol; Lignans; Phytochemicals; Plant Stems; Polycyclic Compounds; Schisandra; Sitosterols | 2014 |
A new 9,10-dihydrophenanthrene from Dendrobium moniliforme.
Topics: Benzaldehydes; Bibenzyls; Cinnamates; Coumaric Acids; Dendrobium; Furans; Guaiacol; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Phenanthrenes; Phenylpropionates; Plants, Medicinal; Sitosterols; Spectrometry, Mass, Electrospray Ionization; Tyramine | 2016 |
Meso-dihydroguaiaretic acid induces apoptosis and inhibits cell migration via p38 activation and EGFR/Src/intergrin β3 downregulation in breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; ErbB Receptors; Female; Genes, src; Guaiacol; Humans; Integrin beta3; Lignans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; p38 Mitogen-Activated Protein Kinases | 2015 |
meso-Dihydroguaiaretic acid attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Cell Movement; Chemokine CCL2; Cytokines; Female; Guaiacol; Humans; Immunoglobulin E; Lignans; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Pneumonia; Saururaceae; Th2 Cells; Vascular Cell Adhesion Molecule-1 | 2016 |
A new (propylphenyl)bibenzyl from Eria bambusifolia.
Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Line, Tumor; Dendrobium; Guaiacol; Humans; Lignans; Stilbenes | 2016 |
Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Guaiacol; HeLa Cells; HL-60 Cells; Humans; Inhibitory Concentration 50; Lignans; Listeria; Mitosporic Fungi; Salmonella arizonae; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship | 2016 |
Structure-Antifungal Activity Relationship of Fluorinated Dihydroguaiaretic Acid Derivatives and Preventive Activity against Alternaria alternata Japanese Pear Pathotype.
Topics: Alternaria; Fungicides, Industrial; Guaiacol; Lignans; Plant Diseases; Pyrus; Structure-Activity Relationship | 2017 |
meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity.
Topics: Animals; Anti-Bacterial Agents; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Guaiacol; Lignans; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Vero Cells | 2017 |
Enhancement of Glucose Uptake by Meso-Dihydroguaiaretic Acid through GLUT4 Up-Regulation in 3T3-L1 Adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Glucose; Glucose Transporter Type 4; Guaiacol; Lignans; Mice; PPAR gamma; Up-Regulation | 2017 |
[Chemical Constituents from Stems of Kadsura longipedunculata].
Topics: Chromatography; Guaiacol; Kadsura; Lignans; Molecular Structure; Plant Extracts; Plant Stems | 2016 |
Dibenzylbutane neolignans from Saururus cernuus L. (Saururaceae) displayed anti-Trypanosoma cruzi activity via alterations in the mitochondrial membrane potential.
Topics: Animals; Brazil; Cells, Cultured; Guaiacol; Lignans; Macrophages, Peritoneal; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Molecular Structure; Phytochemicals; Plant Leaves; Reactive Oxygen Species; Saururaceae; Trypanocidal Agents; Trypanosoma cruzi | 2019 |
Cinnamophilin overcomes cancer multi-drug resistance via allosterically modulating human P-glycoprotein on both drug binding sites and ATPase binding sites.
Topics: Adenosine Triphosphatases; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Cycle; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Guaiacol; Humans; Lignans; Molecular Docking Simulation; Rhodamine 123; Verapamil | 2021 |