guaiacol has been researched along with gigantol in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 17 (54.84) | 24.3611 |
| 2020's | 7 (22.58) | 2.80 |
| Authors | Studies |
|---|---|
| Hao, XJ; Qin, HL; Wang, ZT; Xu, LS; Yang, XS; Zhang, JX | 1 |
| Castillo, R; Hernández-Romero, Y; Mata, R; Rojas, A; Rojas, JI | 1 |
| Abbas, HK; Acevedo, L; Hernández-Romero, Y; Mata, R; Sánchez, Mde L; Shier, WT | 1 |
| Estrada-Soto, S; López-Guerrero, JJ; Mata, R; Villalobos-Molina, R | 1 |
| Back, NI; Choi, MS; Chung, HG; Chung, SA; Jeong, TS; Kim, JY; Lee, JH; Lee, KT; Won, JH; Yun, KJ | 1 |
| Déciga-Campos, M; Mata, R; Palacios-Espinosa, JF; Reyes-Ramírez, A | 1 |
| Shao, L; Wang, L; Wang, ZT; Xu, LS; Zhang, CF; Zhang, M | 1 |
| Kong, H; Lu, X; Xu, G; Xu, Z; Zhou, J | 1 |
| Figueroa, M; González-Andrade, M; Leyte-Lugo, M; Mata, R; Reyes-Ramírez, A; Serrano-Alba, T | 1 |
| Diao, H; Fang, H; Gao, X; Gu, L; Gu, Q; Qi, H; Wang, L; Wang, Z; Wei, X; Yi, Y | 1 |
| Chanvorachote, P; Charoenrungruang, S; Pongrakhananon, V; Sritularak, B | 1 |
| Fan, Y; Han, H; He, C; Wang, Z; Yang, L | 1 |
| Fang, H; Gao, X; Gu, L; Gu, Q; Hu, X; Oliver Chen, CY; Sun, X; Wan, W; Wang, M; Wang, Z; Wei, X; Yang, Q | 1 |
| Chen, L; Chen, Y; Yang, G; Zhang, Y; Zhao, N | 1 |
| Chen, CY; Fang, H; Hu, X; Li, X; Lu, C; Sun, X; Wan, W; Wang, M; Wei, X; Wu, J; Yang, Q | 1 |
| Chanvorachote, P; Pongrakhananon, V; Unahabhokha, T | 1 |
| Chen, L; Chen, Y; Zhan, R; Zhang, Y | 1 |
| Chen, CY; Chen, D; Fang, H; Gao, X; Li, X; Long, Y; Wei, X; Wu, J; Yi, Y | 1 |
| Chen, H; Huang, J; Huang, Y; Lin, L; Wei, G | 1 |
| Chen, CO; Chen, D; Hu, J; Li, X; Ma, W; Wan, W; Wei, X; Wu, J; Yang, Q | 1 |
| Chen, H; Huang, D; Huang, Y; Li, Y; Wei, G; Wu, Z; Zhou, C | 1 |
| Li, S; Li, Y; Liu, S; Liu, ZJ; Lu, D; Song, J; Su, Z; Sun, Q; Wang, M; Wang, Z; Yu, S; Zhang, GQ; Zhang, X; Zhou, L | 1 |
| Chen, MF; Hong, TY; Kao, ST; Liou, SS; Liu, IM | 1 |
| Wan, W; Wei, X; Yang, Q; Yang, Y; Yu, J | 1 |
| Liu, C; Liu, Y; Shi, Q; Wang, J | 1 |
| Deng, QQ; Liu, B; Liu, Q; Ma, ZH; Pan, GY; Peng, ZL; Wang, L; Xue, YR; Yao, S; Ye, Y; Zhou, H | 1 |
| Böttcher, C; Dehlinger, A; Khoonrit, P; Likhitwitayawuid, K; Mekboonsonglarp, W; Mirdogan, A; Priller, J; Sritularak, B | 1 |
| Chen, L; Peng, L; Peng, T; Song, Y; Tao, B; Wu, Y; Xia, K; Xia, X; Yang, X; Zhong, C | 1 |
| Du, H; Duan, S; Huang, C; Huang, J; Lin, J; Liu, C; Luo, Y; Tao, S; Wang, H; Wei, G; Xing, S; Zhang, X | 1 |
| Hu, X; Kang, H; Liu, L; Sun, Y | 1 |
| Chen, X; Li, H; Li, J; Li, S; Li, X; Xue, X; Yi, Y; Yin, D | 1 |
31 other study(ies) available for guaiacol and gigantol
| Article | Year |
|---|---|
[Analysis of 1H-NMR fingerprint in stem of Dendrobium loddigesii].
Topics: Benzyl Compounds; Bibenzyls; Dendrobium; Guaiacol; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Stems; Plants, Medicinal; Species Specificity | 2002 |
Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.
Topics: Animals; Bibenzyls; Brain; Cattle; Dose-Response Relationship, Drug; Flavonoids; Guaiacol; Guinea Pigs; Ileum; Inhibitory Concentration 50; Mexico; Models, Biological; Molecular Conformation; Molecular Structure; Muscle Contraction; Orchidaceae; Parasympatholytics; Phosphoric Diester Hydrolases; Plants, Medicinal; Spiro Compounds; Stilbenes; Structure-Activity Relationship | 2004 |
Phytotoxic activity of bibenzyl derivatives from the orchid Epidendrum rigidum.
Topics: Amaranthus; Araceae; Bibenzyls; Chemical Fractionation; Guaiacol; Herbicides; Orchidaceae; Plant Extracts; Seedlings; Stilbenes | 2005 |
Endothelium-independent relaxation of aorta rings by two stilbenoids from the orchids Scaphyglottis livida.
Topics: Animals; Aorta; Bibenzyls; Guaiacol; Male; Medicine, Traditional; Orchidaceae; Phenanthrenes; Rats; Rats, Wistar; Sodium; Stilbenes; Vasodilation; Vasodilator Agents | 2006 |
Gigantol isolated from the whole plants of Cymbidium goeringii inhibits the LPS-induced iNOS and COX-2 expression via NF-kappaB inactivation in RAW 264.7 macrophages cells.
Topics: Animals; Anti-Inflammatory Agents; Bibenzyls; Cell Line; Chemical Fractionation; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Genes, Reporter; Guaiacol; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Orchidaceae; RNA, Messenger; Tumor Necrosis Factor-alpha | 2006 |
Antinociceptive and anti-inflammatory effects of compounds isolated from Scaphyglottis livida and Maxillaria densa.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bibenzyls; Carrageenan; Chromatography, High Pressure Liquid; Edema; Guaiacol; Magnetic Resonance Spectroscopy; Male; Mexico; Mice; Mice, Inbred ICR; Orchidaceae; Pain Measurement; Plant Extracts; Rats; Rats, Sprague-Dawley; Reaction Time; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared | 2007 |
[Studies on chemical constituents of Dendrobium crystallinum].
Topics: Bibenzyls; Chromatography; Dendrobium; Drugs, Chinese Herbal; Flavanones; Guaiacol; Magnetic Resonance Spectroscopy; Parabens; Sitosterols; Stigmasterol | 2008 |
[Comparison of phenolic components among different species of Dendrobium (Shihu fengdou) and determination of their active components--moscatilin and gigantol].
Topics: Benzyl Compounds; Bibenzyls; Chromatography, Liquid; Dendrobium; Guaiacol; Hydroxybenzoates; Mass Spectrometry; Species Specificity | 2010 |
Synthesis, biological evaluation, and docking studies of gigantol analogs as calmodulin inhibitors.
Topics: Anesthetics, Local; Antidepressive Agents; Antineoplastic Agents; Antipsychotic Agents; Bibenzyls; Biosensing Techniques; Biphenyl Compounds; Calmodulin; Chlorpromazine; Cyclic Nucleotide Phosphodiesterases, Type 1; Guaiacol; Humans; Molecular Docking Simulation; Parasympatholytics; Protein Binding; Trifluoperazine | 2011 |
[Study on anti-cataract effect of gigantol combined with syringic acid and their mechanism].
Topics: Aldehyde Reductase; Animals; Bibenzyls; Cataract; Drug Synergism; Female; Gallic Acid; Guaiacol; Humans; In Vitro Techniques; Lens, Crystalline; Male; Rats; Rats, Wistar | 2012 |
Gigantol, a bibenzyl from Dendrobium draconis, inhibits the migratory behavior of non-small cell lung cancer cells.
Topics: Antineoplastic Agents; Bibenzyls; Carcinoma, Non-Small-Cell Lung; Caveolin 1; Cell Movement; Cell Proliferation; Cell Survival; Dendrobium; Drug Screening Assays, Antitumor; Guaiacol; Humans; Keratinocytes; Lung Neoplasms; Molecular Structure; Proto-Oncogene Proteins c-akt; Signal Transduction | 2014 |
Identification of the metabolites of gigantol in rat urine by ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
Topics: Animals; Bibenzyls; Chromatography, High Pressure Liquid; Guaiacol; Male; Metabolic Networks and Pathways; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats.
Topics: Animals; Antioxidants; Bibenzyls; Cataract; Dendrobium; Drugs, Chinese Herbal; Galactosemias; Guaiacol; Lens, Crystalline; Medicine, Chinese Traditional; Molecular Docking Simulation; Osmotic Pressure; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction | 2015 |
A new 9,10-dihydrophenanthrene from Dendrobium moniliforme.
Topics: Benzaldehydes; Bibenzyls; Cinnamates; Coumaric Acids; Dendrobium; Furans; Guaiacol; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Phenanthrenes; Phenylpropionates; Plants, Medicinal; Sitosterols; Spectrometry, Mass, Electrospray Ionization; Tyramine | 2016 |
Synthesis and Biological Evaluation of Novel Gigantol Derivatives as Potential Agents in Prevention of Diabetic Cataract.
Topics: Aldehyde Reductase; Apoptosis; Bibenzyls; Cataract; Cell Survival; Cells, Cultured; Diabetes Complications; Enzyme Inhibitors; Epithelial Cells; Guaiacol; Humans; Hypoglycemic Agents; Lens, Crystalline; Molecular Structure; Nitric Oxide Synthase Type II; Structure-Activity Relationship | 2015 |
The attenuation of epithelial to mesenchymal transition and induction of anoikis by gigantol in human lung cancer H460 cells.
Topics: Anoikis; Apoptosis; Bibenzyls; Blotting, Western; Cadherins; Carcinoma, Non-Small-Cell Lung; Caveolin 1; Cell Proliferation; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Guaiacol; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Cells, Cultured; Vimentin | 2016 |
A new (propylphenyl)bibenzyl from Eria bambusifolia.
Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Line, Tumor; Dendrobium; Guaiacol; Humans; Lignans; Stilbenes | 2016 |
Investigation of synergistic mechanism and identification of interaction site of aldose reductase with the combination of gigantol and syringic acid for prevention of diabetic cataract.
Topics: Aldehyde Reductase; Animals; Bibenzyls; Cataract; Cell Line; Cell Survival; Diabetes Complications; Disease Models, Animal; Drug Synergism; Female; Gallic Acid; Guaiacol; Humans; Male; Rats; Rats, Wistar | 2016 |
Gigantol attenuates the proliferation of human liver cancer HepG2 cells through the PI3K/Akt/NF-κB signaling pathway.
Topics: Apoptosis; Bibenzyls; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Flow Cytometry; Guaiacol; Humans; Immunoenzyme Techniques; Liver Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured | 2017 |
Gigantol from Dendrobium chrysotoxum Lindl. binds and inhibits aldose reductase gene to exert its anti-cataract activity: An in vitro mechanistic study.
Topics: Aldehyde Reductase; Bibenzyls; Cataract; Cells, Cultured; Dendrobium; Diabetes Complications; Epithelial Cells; Gene Expression Regulation, Enzymologic; Glucose; Guaiacol; Humans; Lens, Crystalline; Reverse Transcriptase Polymerase Chain Reaction; Spectrum Analysis, Raman | 2017 |
Protective effect of gigantol against hydrogen peroxide‑induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.
Topics: Animals; Antioxidants; Apoptosis; Bibenzyls; Cell Survival; Cells, Cultured; Cytoprotection; Guaiacol; Hydrogen Peroxide; Male; Mesenchymal Stem Cells; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2018 |
Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Bibenzyls; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Guaiacol; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Orchidaceae; Phosphorylation; Plant Extracts; Wnt Signaling Pathway | 2018 |
Gigantol has Protective Effects against High Glucose-Evoked Nephrotoxicity in Mouse Glomerulus Mesangial Cells by Suppressing ROS/MAPK/NF-κB Signaling Pathways.
Topics: Animals; Apoptosis; Bibenzyls; Cell Line; Cell Survival; Cells, Cultured; Diabetic Nephropathies; Glucose; Guaiacol; Lipid Peroxidation; Mesangial Cells; Mice; Mitochondria; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction | 2018 |
Characterization of structural requirement for binding of gigantol and aldose reductase.
Topics: Aldehyde Reductase; Animals; Bibenzyls; Binding Sites; Catalysis; Cataract; Female; Guaiacol; Lens, Crystalline; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Protein Binding; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2019 |
Characterization of the metabolites of gigantol in rat, dog, monkey, and human hepatocytes using ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry.
Topics: Animals; Bibenzyls; Cells, Cultured; Chromatography, High Pressure Liquid; Dogs; Guaiacol; Haplorhini; Hepatocytes; Humans; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2020 |
Dihydro-stilbene gigantol relieves CCl
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Bibenzyls; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Complement Membrane Attack Complex; Guaiacol; Hepatocytes; Humans; Inflammation; Lipid Peroxidation; Lithocholic Acid; Liver; Male; Mice, Inbred ICR; Oxidative Stress; Phenanthrenes; Proteome; Rats, Sprague-Dawley; Stilbenes | 2020 |
Immune modulatory effect of a novel 4,5-dihydroxy-3,3´,4´-trimethoxybibenzyl from Dendrobium lindleyi.
Topics: Benzyl Compounds; Bibenzyls; Cells, Cultured; Dendrobium; Guaiacol; Humans; Immunologic Factors; Monocytes; Naphthoquinones; Phenanthrenes; Plant Extracts | 2020 |
Matrix stiffness promotes glioma cell stemness by activating BCL9L/Wnt/β-catenin signaling.
Topics: AC133 Antigen; Acrylic Resins; Animals; Antineoplastic Agents; Bibenzyls; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Extracellular Matrix; Glioma; Guaiacol; Humans; Mice; Microscopy, Atomic Force; Neoplasm Grading; Neoplasm Transplantation; Neoplastic Stem Cells; Radiotherapy; Transcription Factors; Tumor Microenvironment; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2021 |
Gigantol inhibits proliferation and enhances DDP-induced apoptosis in breast-cancer cells by downregulating the PI3K/Akt/mTOR signaling pathway.
Topics: Antineoplastic Agents; Apoptosis; Bibenzyls; Breast Neoplasms; Cell Proliferation; Cisplatin; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Guaiacol; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2021 |
Gigantol inhibits proliferation and enhanced oxidative stress-mediated apoptosis through modulating of Wnt/β-catenin signaling pathway in HeLa cells.
Topics: Apoptosis; beta Catenin; Bibenzyls; Cell Proliferation; Guaiacol; HeLa Cells; Humans; Oxidative Stress; Wnt Signaling Pathway | 2022 |
Effect of gigantol on the proliferation of hepatocellular carcinoma cells tested by a network-based pharmacological approach and experiments.
Topics: Bibenzyls; Carcinoma, Hepatocellular; Cell Proliferation; Guaiacol; Humans; Liver Neoplasms; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases | 2022 |