Compounds > gr 89696

gr 89696 and naloxone

gr 89696 has been researched along with naloxone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Englberger, W; Geiger, C; Lehmkuhl, K; Schepmann, D; Wünsch, B; Zelenka, C1
Rack, E; Schepmann, D; Sunnam, SK; Wünsch, B1
Autar, R; Bouzanne des Mazery, R; Fröhlich, R; Molenveld, P; Schepmann, D; Soeberdt, M; Sterk, GJ; Storcken, RP; van der Haas, RN; van Oss, B; Wünsch, B1
Aiello, D; Diana, P; Jonas, H; Schepmann, D; Wünsch, B1
Headley, PM; Herrero, JF1
Lasukova, TV; Lishmanov, AIu; Maslov, LN; Platonov, AA1

Other Studies

6 other study(ies) available for gr 89696 and naloxone

ArticleYear
Conformationally constrained kappa receptor agonists: stereoselective synthesis and pharmacological evaluation of 6,8-diazabicyclo[3.2.2]nonane derivatives.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Animals; Azabicyclo Compounds; Cell Line; Guinea Pigs; Humans; In Vitro Techniques; Molecular Conformation; Radioligand Assay; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship

2010
Synthesis of 7,9-diazabicyclo[4.2.2]decanes as conformationally restricted κ receptor agonists: fine tuning of the dihedral angle of the ethylenediamine pharmacophore.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Azabicyclo Compounds; Ethylenediamines; Guinea Pigs; Ligands; Models, Molecular; Molecular Structure; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship

2011
Conformationally restricted κ-opioid receptor agonists: Synthesis and pharmacological evaluation of diastereoisomeric and enantiomeric decahydroquinoxalines.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Crystallography, X-Ray; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Piperazines; Protein Binding; Pyrrolidines; Quinoxalines; Receptors, Opioid, kappa; Stereoisomerism

2015
Synthesis of 8-aminomorphans with high KOR affinity.
    European journal of medicinal chemistry, 2022, Feb-15, Volume: 230

    Topics: Molecular Conformation; Pyrrolidines; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship

2022
Functional evidence for multiple receptor activation by kappa-ligands in the inhibition of spinal nociceptive reflexes in the rat.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Anticonvulsants; Benzeneacetamides; Benzofurans; Blood Pressure; Decerebrate State; Male; Naloxone; Nociceptors; Piperazines; Pyrroles; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord; Thiophenes

1993
[Role of kappa-opioid receptors in the regulation of cardiac resistance to arrhythmogenic effects of ischemia and reperfusion].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2006, Volume: 92, Issue:12

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Myocardial Reperfusion Injury; Myocardium; Naloxone; Naltrexone; Piperazines; Pyrrolidines; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Opioid, kappa

2006