gr 73632 has been researched along with aprepitant in 3 studies
Studies (gr 73632) | Trials (gr 73632) | Recent Studies (post-2010) (gr 73632) | Studies (aprepitant) | Trials (aprepitant) | Recent Studies (post-2010) (aprepitant) |
---|---|---|---|---|---|
77 | 1 | 9 | 769 | 229 | 521 |
Protein | Taxonomy | gr 73632 (IC50) | aprepitant (IC50) |
---|---|---|---|
Cytochrome P450 3A4 | Homo sapiens (human) | 0.046 | |
Substance-P receptor | Homo sapiens (human) | 0.0002 | |
Substance-P receptor | Meriones unguiculatus (Mongolian gerbil) | 0.0001 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ballard, TM; Haman, M; Higgins, GA; Woolley, ML | 1 |
Asai, H; Ishii, T; Kiuchi, S; Nagasaki, M; Okamoto, M; Saito, A; Taniguchi, H; Watanabe, Y | 1 |
Bettelini, L; Corsi, M; Costantini, VJ; Dünstl, G; Gerrard, P; Zonzini, L | 1 |
3 other study(ies) available for gr 73632 and aprepitant
Article | Year |
---|---|
Investigating the effect of bilateral amygdala lesions on fear conditioning and social interaction in the male Mongolian gerbil.
Topics: Amygdala; Analysis of Variance; Animals; Aprepitant; Behavior, Animal; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Interactions; Fear; Gerbillinae; Ibotenic Acid; Immobility Response, Tonic; Interpersonal Relations; Male; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Substance P | 2006 |
Pharmacological characterization of T-2328, 2-fluoro-4'-methoxy-3'-[[[(2S,3S)-2-phenyl-3-piperidinyl]amino]methyl]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride, as a brain-penetrating antagonist of tachykinin NK1 receptor.
Topics: Animals; Antiemetics; Antineoplastic Agents; Aprepitant; Binding Sites; Brain; Cell Line, Tumor; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Ferrets; Gerbillinae; Humans; Kinetics; Male; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Substance P; Transfection; Vomiting | 2008 |
The NK1 receptor antagonist aprepitant attenuates NK1 agonist-induced scratching behaviour in the gerbil after intra-dermal, topical or oral administration.
Topics: Administration, Oral; Administration, Topical; Animals; Antipruritics; Aprepitant; Disease Models, Animal; Drug Evaluation, Preclinical; Gerbillinae; Humans; Injections, Intradermal; Morpholines; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Pruritus; Receptors, Neurokinin-1; Substance P | 2015 |