Page last updated: 2024-09-02

geniposide and genipin

geniposide has been researched along with genipin in 47 studies

Compound Research Comparison

Studies
(geniposide)
Trials
(geniposide)
Recent Studies (post-2010)
(geniposide)
Studies
(genipin)
Trials
(genipin)
Recent Studies (post-2010) (genipin)
49603718623668

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.26)18.2507
2000's15 (31.91)29.6817
2010's26 (55.32)24.3611
2020's4 (8.51)2.80

Authors

AuthorsStudies
Apers, S; Cimanga, K; Claeys, M; Hermans, N; Pieters, L; Van den Heuvel, H; Van Miert, S; Vlietinck, A1
Fong, HH; Mesecar, AD; Rong, L; Rothwangl, K; Sabahi, A; Zhang, H1
Chen, L; Peng, K; Qiu, F; Yang, L; Zhao, F; Zhao, S1
Chen, CL; Hsu, WY; Huang, SM; Hung, CH; Hung, YL; Lai, CC; Lai, CH; Lin, CW; Lin, TH; Lin, YJ; Liu, X; Sue, SC; Tien, N; Tsai, FJ1
Chowdhury, SR; Du, Y; Fu, L; Jiang, F; Lei, S; Qi, Y; Sun, R; Wang, J; Zhang, D1
Morita, S; Noda, T; Ohmori, M; Shimizu, M; Tsujimoto, Y; Yamada, A; Yamano, T1
Chiba, K; Mohri, T; Yamazaki, M1
Amagaya, S; Fukuda, K; Ishige, A; Ito, T; Komatsu, Y; Miura, N; Ohtake, N; Sasaki, H; Terasawa, K; Yamamoto, M1
Ikeda, Y; Kondo, K; Suzuki, Y; Umemura, K1
Iwasaki, Y; Takeda, Y; Ueno, K; Yoshizaki, F1
Endo, G; Furusawa, N; Kitano, M; Kuroda, K; Ozaki, A; Yamaguchi, H1
Akita, H; Ikegami, T; Ito, K; Kano, M; Miura, T; Oda, K; Shoda, J; Sugiyama, Y; Suzuki, H; Tanaka, N; Utsunomiya, H; Yamamoto, M1
Eguchi, Y; Fujimori, K; Fujiwara, K; Inao, M; Kakinuma, T; Matsui, A; Mochida, S; Nagoshi, S; Naiki, K; Wang, Y; Yulutuz, Y1
Bae, HS; Cho, KH; Kim, DH; Kim, JJ; Kim, YS; Moon, SK; Park, EK; Yim, JS1
Jung, HJ; Koo, HJ; Lim, KH; Park, EH1
Liu, X; Lou, H1
Chen, C; Han, F; Lu, J; Shi, Y; Zhang, Y1
Chao, PD; Chen, YS; Hou, YC; Lai, PY; Tsai, SY1
Huang, CM; Lee, WC; Liao, HJ; Tsai, TH; Wang, SC1
Itoh, K; Lelono, RA; Tachibana, S1
Ding, Y; Jin, D; Qiu, C; Yang, YS; Yu, SC; Zhang, LY; Zhang, T1
Gao, X; Han, L; He, W; Liu, E; Shang, H; Wang, J; Wang, T1
Ahn, YT; Choi, JH; Do, MT; Jeong, HG; Jeong, TC; Kang, MJ; Kang, W; Khanal, T; Kim, DH; Kim, HG; Kong, MJ; Noh, K; Yeo, HK1
Ahn, YT; Jeong, HG; Jeong, TC; Kang, MJ; Khanal, T; Kim, DH; Kim, HG; Lee, DH; Lee, YS; Yeo, HK1
Liu, H; Wei, SF; Yang, M; Zhang, HY1
Bi, YA; Cheng, NH; Ding, G; Meng, ZQ; Niu, XS; Wang, ZZ; Xiao, W; Zhu, JY1
Diao, J; Gong, G; Liu, H; Wang, L; Wang, P; Zhao, G; Zheng, Z1
Bi, K; He, C; Hu, H; Li, Z; Song, M; Wang, Z; Welbeck, E; Yang, L1
Chen, B; Huang, X; Qian, H; Zhao, B; Zhu, Y1
Cai, Q; Cai, W; Che, Y; Li, Y; Zhang, J; Zhao, B1
Gao, Y; Huang, C; Jiang, P; Jiang, W; Li, Z; Lian, S; Ma, Y; Tian, X; Xu, Z1
Che, X; Fan, H; Wang, M; Wang, T; Wang, W; Xu, H; Yang, M1
Liu, S; Liu, Z; Pi, Z; Song, F; Zhang, X1
Chang, D; Hua, Q; Li, F; Li, W; Li, Y; Wang, X; Zhang, A; Zhang, Z1
Chang, CH; Hsu, YM; Lai, YJ; Lu, CC; Su, CH; Wu, JB; Yang, JS1
Maróstica Júnior, MR; Meireles, MAA; Náthia-Neves, G; Tarone, AG; Tosi, MM1
Feng, X; Liu, H; Park, KY; Qian, Y; Song, JL; Sun, P; Yi, R; Zhao, X1
Ding, Y; Yang, Y; Zhang, T1
Chen, G; Liu, T; Sui, X; Sun, J; Wang, H; Xu, T; Zhang, J1
Chen, M; Huang, C; Li, Z; Liu, F; Liu, H; Ma, L; Sun, Z; Tian, Q; Xu, Z; Yin, H1
Chen, MK; Hsieh, CL; Huang, SM; Maner, RS; Peng, CC; Zulkefli, ND1
Chen, H; Ju, Z; Lin, H; Liu, X; Lu, W; Zhu, H1
Huang, L; Jiang, N; Li, X; Li, Y; Lu, Y; Pan, H; Shi, F1
Dong, L; Gao, X; Lan, M; Li, C; Luo, G; Lv, J; Sun, J; Zhang, H; Zhang, Y1
Chen, J; Chen, Y; Huang, M; Li, F; Li, Y; Song, L; Zhao, W1
Chang, R; Gao, F; Luo, Y; Wen, J; Wu, J; Zhang, X; Zhong, J; Zhou, T1
Chen, H; Chen, X; Guo, C; Huang, C; Huang, H; Li, N; Lv, N; Xing, H; Zhang, Y; Zhao, D; Zhao, Y1

Other Studies

47 other study(ies) available for geniposide and genipin

ArticleYear
Complement-inhibiting iridoids from Morinda morindoides.
    Journal of natural products, 2003, Volume: 66, Issue:1

    Topics: Complement Inactivator Proteins; Complement Pathway, Alternative; Complement Pathway, Classical; Democratic Republic of the Congo; Dose-Response Relationship, Drug; Flavonoids; Hemolysis; Humans; Inhibitory Concentration 50; Iridoids; Morinda; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal

2003
Lamiridosins, hepatitis C virus entry inhibitors from Lamium album.
    Journal of natural products, 2009, Volume: 72, Issue:12

    Topics: Antiviral Agents; Hepacivirus; Iridoids; Lamiaceae; Molecular Structure; Plants, Medicinal; Stereoisomerism

2009
Chemical constituents from the fruit of Gardenia jasminoides and their inhibitory effects on nitric oxide production.
    Bioorganic & medicinal chemistry letters, 2013, Feb-15, Volume: 23, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Fruit; Gardenia; Nitric Oxide

2013
Inhibition of enterovirus 71 infections and viral IRES activity by Fructus gardeniae and geniposide.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Antiviral Agents; Cell Line, Tumor; Drugs, Chinese Herbal; Enterovirus A, Human; Enterovirus Infections; Gardenia; Humans; Iridoids; Medicine, Chinese Traditional; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Biosynthesis; Ribosomes; RNA, Viral; Virus Replication

2013
Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors.
    European journal of medicinal chemistry, 2020, Nov-01, Volume: 205

    Topics: Biological Transport; Cell Line; Chemistry Techniques, Synthetic; Enzyme Inhibitors; Glucose; Inhibitory Concentration 50; Insulin; Iridoids; Molecular Docking Simulation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Structure-Activity Relationship; Sulfonic Acids

2020
Hepatotoxicity of geniposide in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1990, Volume: 28, Issue:7

    Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Buthionine Sulfoximine; Chloramphenicol; Cysteine; Injections, Intraperitoneal; Iridoid Glycosides; Iridoids; Liver; Male; Methionine Sulfoximine; Molecular Structure; Pyrans; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1990
Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein kinases.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:6

    Topics: Animals; beta-Glucosidase; Calcium; Glucosides; Hydrolysis; Iridoid Glucosides; Iridoid Glycosides; Iridoids; Neurites; Neurons; PC12 Cells; Protein Kinase Inhibitors; Pyrans; Rats; Signal Transduction

1996
Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Cells, Cultured; Cholagogues and Choleretics; fas Receptor; Female; Glycyrrhizic Acid; Intracellular Membranes; Iridoid Glycosides; Iridoids; Liver; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Permeability; Plants, Medicinal; Pyrans; Ursodeoxycholic Acid

2000
Antithrombotic effect of geniposide and genipin in the mouse thrombosis model.
    Planta medica, 2001, Volume: 67, Issue:9

    Topics: Animals; Disease Models, Animal; Fibrinolytic Agents; Fruit; Iridoid Glycosides; Iridoids; Male; Mice; Phospholipases A; Phytotherapy; Plant Extracts; Platelet Aggregation; Pyrans; Rubiaceae; Thrombosis

2001
Simultaneous estimation of geniposide and genipin in mouse plasma using high-performance liquid chromatography.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2001, Volume: 17, Issue:10

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Humans; Iridoid Glycosides; Iridoids; Male; Mice; Mice, Inbred Strains; Plant Extracts; Pyrans; Rubiaceae

2001
Genotoxicity of gardenia yellow and its components.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:11

    Topics: Bacillus subtilis; Carotenoids; Coloring Agents; Disaccharides; DNA Damage; Electrophoresis, Capillary; Food Coloring Agents; Gardenia; Iridoid Glycosides; Iridoids; Mutagenicity Tests; Plant Extracts; Pyrans; Sister Chromatid Exchange; Vitamin A

2002
Genipin enhances Mrp2 (Abcc2)-mediated bile formation and organic anion transport in rat liver.
    Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:1

    Topics: Actin Cytoskeleton; Adenosine Triphosphate; Administration, Oral; Animals; Anions; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile; Cholagogues and Choleretics; Drugs, Chinese Herbal; Estradiol; Gene Expression; In Vitro Techniques; Iridoid Glycosides; Iridoids; Liver; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Phalloidine; Pyrans; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tritium

2004
Japanese herbal medicine Inchin-ko-to as a therapeutic drug for liver fibrosis.
    Journal of hepatology, 2004, Volume: 41, Issue:4

    Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Cholagogues and Choleretics; Drugs, Chinese Herbal; Iridoid Glycosides; Iridoids; Liver; Liver Cirrhosis, Experimental; Necrosis; Pyrans; Rats; Rats, Inbred F344; Survival Analysis; Swine

2004
Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:10

    Topics: Adult; Chromatography, Thin Layer; Feces; Female; Flavanones; Flavonoids; Ginsenosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; In Vitro Techniques; Iridoid Glycosides; Iridoids; Male; Panax; Plant Extracts; Pyrans; Scutellaria baicalensis; Stereoisomerism

2004
Anti-inflammatory evaluation of gardenia extract, geniposide and genipin.
    Journal of ethnopharmacology, 2006, Feb-20, Volume: 103, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fruit; Gardenia; Inflammation; Iridoid Glycosides; Iridoids; Male; Mice; Nitrates; Plant Extracts; Pyrans; Rats; Rats, Sprague-Dawley

2006
Synthesis of monoterpene alkaloid derivatives from the iridoid glucoside geniposide.
    Natural product research, 2007, Volume: 21, Issue:13

    Topics: Alkaloids; Amino Acids; Fruit; Gardenia; Iridoid Glycosides; Iridoids; Magnetic Resonance Spectroscopy; Monoterpenes; Pyrans; Spectrometry, Mass, Electrospray Ionization

2007
Simultaneous determination of geniposide and its metabolites genipin and genipinine in culture of Aspergillus niger by HPLC.
    Biomedical chromatography : BMC, 2008, Volume: 22, Issue:7

    Topics: Aspergillus niger; Biological Availability; Caco-2 Cells; Chromatography, High Pressure Liquid; Humans; Iridoid Glycosides; Iridoids; Linear Models; Pyridines; Sensitivity and Specificity

2008
Metabolism and pharmacokinetics of genipin and geniposide in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:8

    Topics: Animals; Calibration; Chemical Phenomena; Chemistry, Physical; Cholagogues and Choleretics; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Gardenia; Hydrolysis; Injections, Intravenous; Iridoid Glycosides; Iridoids; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2008
Using orthogonal array to obtain gradient liquid chromatography conditions of enhanced peak intensity to determine geniposide and genipin with electrospray tandem mass spectrometry.
    Journal of chromatography. A, 2008, Nov-28, Volume: 1212, Issue:1-2

    Topics: Animals; Calibration; Chromatography, Liquid; Gardenia; Iridoid Glycosides; Iridoids; Rats; Reference Standards; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008
Isolation of antifungal compounds from Gardenia jasminoides.
    Pakistan journal of biological sciences : PJBS, 2009, Jul-01, Volume: 12, Issue:13

    Topics: Antifungal Agents; Cholagogues and Choleretics; Fungi; Gardenia; Iridoid Glycosides; Iridoids; Microbial Sensitivity Tests; Molecular Structure; Plant Extracts

2009
Transformation of geniposide into genipin by immobilized β-glucosidase in a two-phase aqueous-organic system.
    Molecules (Basel, Switzerland), 2011, May-24, Volume: 16, Issue:5

    Topics: beta-Glucosidase; Enzyme Stability; Hydrogen-Ion Concentration; Hydrolysis; Iridoid Glycosides; Iridoids; Organic Chemistry Phenomena; Temperature; Time Factors

2011
Eucommia ulmoides bark protects against renal injury in cadmium-challenged rats.
    Journal of medicinal food, 2012, Volume: 15, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cadmium Poisoning; Drug Discovery; Drugs, Chinese Herbal; Eucommiaceae; Iridoids; Kidney; Macrophage Activation; Male; Mice; Mice, Inbred Strains; Nitric Oxide; Oxidative Stress; Plant Bark; Protective Agents; Rats; Rats, Sprague-Dawley; Renal Insufficiency

2012
Biotransformation of geniposide by human intestinal microflora on cytotoxicity against HepG2 cells.
    Toxicology letters, 2012, Mar-25, Volume: 209, Issue:3

    Topics: Apoptosis; bcl-2-Associated X Protein; Biotransformation; Blotting, Western; Caspase 3; Cell Survival; Feces; Female; Hep G2 Cells; Humans; In Situ Nick-End Labeling; Intestines; Iridoids; Male; MAP Kinase Signaling System; Molecular Structure; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

2012
Role of metabolism by human intestinal microflora in geniposide-induced toxicity in HepG2 cells.
    Archives of pharmacal research, 2012, Volume: 35, Issue:4

    Topics: Bacteroides fragilis; Bifidobacterium; Biotransformation; Cell Survival; Dose-Response Relationship, Drug; Feces; Hep G2 Cells; Humans; Intestines; Iridoids

2012
Antithrombotic activities of aqueous extract from Gardenia jasminoides and its main constituent.
    Pharmaceutical biology, 2013, Volume: 51, Issue:2

    Topics: Administration, Oral; Animals; Arteriovenous Shunt, Surgical; Aspirin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Fruit; Gardenia; Iridoids; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Solvents; Time Factors; Venous Thrombosis; Water

2013
[Orthogonal test for preparing genipin with enzymolyzed geniposide].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:21

    Topics: Hydrolysis; Iridoids; Technology, Pharmaceutical

2012
Purification and characterization of a β-glucosidase from aspergillus niger and its application in the hydrolysis of geniposide to genipin.
    Journal of microbiology and biotechnology, 2014, Jun-28, Volume: 24, Issue:6

    Topics: Aspergillus niger; Biotransformation; Enzyme Stability; Fungal Proteins; Glucosidases; Iridoids; Kinetics

2014
A quantitative ¹H nuclear magnetic resonance (qHNMR) method for assessing the purity of iridoids and secoiridoids.
    Fitoterapia, 2015, Volume: 100

    Topics: Chromatography, High Pressure Liquid; Iridoid Glucosides; Iridoids; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrones; Reproducibility of Results; Sensitivity and Specificity

2015
A Substrate Fed-Batch Biphasic Catalysis Process for the Production of Natural Crosslinking Agent Genipin with Fusarium solani ACCC 36223.
    Journal of microbiology and biotechnology, 2015, Volume: 25, Issue:6

    Topics: Batch Cell Culture Techniques; Cross-Linking Reagents; Culture Media; Fusarium; Hydrolysis; Iridoids

2015
Comprehensive characterization of the in vitro and in vivo metabolites of geniposide in rats using ultra-high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometer.
    Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Iridoids; Male; Mass Spectrometry; Metabolome; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization

2016
Comprehensive Evaluation of the Metabolism of Genipin-1-β-d-gentiobioside in Vitro and in Vivo by Using HPLC-Q-TOF.
    Journal of agricultural and food chemistry, 2016, Jul-13, Volume: 64, Issue:27

    Topics: Animals; Chromatography, High Pressure Liquid; Glycosylation; Hepatocytes; Hydroxylation; Iridoids; Male; Mass Spectrometry; Molecular Structure; Rats; Rats, Sprague-Dawley

2016
Evaluation of the Antidepressant Activity, Hepatotoxicity and Blood Brain Barrier Permeability of Methyl Genipin.
    Molecules (Basel, Switzerland), 2016, Jul-16, Volume: 21, Issue:7

    Topics: Animals; Antidepressive Agents; Blood-Brain Barrier; Body Weight; Brain; Chromatography, High Pressure Liquid; Iridoids; Liver; Molecular Structure; Permeability; Rats; Tissue Distribution

2016
Simultaneous quantification method for comparative pharmacokinetics studies of two major metabolites from geniposide and genipin by online mircrodialysis-UPLC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Jan-15, Volume: 1041-1042

    Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Iridoids; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2017
In Vitro Selection of DNA Aptamers that Binds Geniposide.
    Molecules (Basel, Switzerland), 2017, Feb-28, Volume: 22, Issue:3

    Topics: Aptamers, Nucleotide; Gardenia; Glucose; Iridoids; Medicine, Chinese Traditional; Plant Extracts; SELEX Aptamer Technique

2017
The Suppressive Effects of Geniposide and Genipin on Helicobacter pylori Infections In Vitro and In Vivo.
    Journal of food science, 2017, Volume: 82, Issue:12

    Topics: Animals; Drugs, Chinese Herbal; Gardenia; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Inflammation Mediators; Iridoids; Male; Mice; Mice, Inbred C57BL

2017
Extraction of bioactive compounds from genipap (Genipa americana L.) by pressurized ethanol: Iridoids, phenolic content and antioxidant activity.
    Food research international (Ottawa, Ont.), 2017, Volume: 102

    Topics: Antioxidants; Ethanol; Food Handling; Fruit; Iridoids; Phenols; Plant Extracts; Rubiaceae; Seeds

2017
    Molecules (Basel, Switzerland), 2018, 05-03, Volume: 23, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carcinoma, Squamous Cell; Caspases; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation; Humans; Iridoids; Lacticaseibacillus casei; Mouth Neoplasms

2018
Biotransformation of Geniposide into Genipin by Immobilized
    BioMed research international, 2018, Volume: 2018

    Topics: Acetylation; beta-Glucosidase; Biotransformation; Cells, Immobilized; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Fermentation; Iridoids; Isomerism; Models, Molecular; Protein Conformation; Proton Magnetic Resonance Spectroscopy; Temperature; Trichoderma

2018
Application of cellulase treatment in ionic liquid based enzyme-assisted extraction in combine with in-situ hydrolysis process for obtaining genipin from Eucommia ulmoides Olive barks.
    Journal of chromatography. A, 2018, Sep-28, Volume: 1569

    Topics: beta-Glucosidase; Cellulase; Chemistry Techniques, Analytical; Eucommiaceae; Hydrolysis; Ionic Liquids; Iridoids

2018
Evaluation of the chemical consistency of Yin-Chen-Hao-Tang prepared by combined and separated decoction methods using high-performance liquid chromatography and quadrupole time-of-flight mass spectrometry coupled with multivariate statistical analysis.
    Journal of separation science, 2019, Volume: 42, Issue:9

    Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Discriminant Analysis; Drugs, Chinese Herbal; Iridoids; Mass Spectrometry; Multivariate Analysis

2019
Geniposide ameliorated fluoxetine-suppressed neurite outgrowth in Neuro2a neuroblastoma cells.
    Life sciences, 2019, Jun-01, Volume: 226

    Topics: Cell Differentiation; Cell Line, Tumor; Cell Survival; Cyclic AMP Response Element-Binding Protein; Fluoxetine; GAP-43 Protein; Humans; Iridoids; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Neural Stem Cells; Neurites; Neuroblastoma; Neurogenesis; Neuronal Outgrowth; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2019
Effects of intron retention on properties of β-glucosidase in Aspergillus niger.
    Fungal biology, 2019, Volume: 123, Issue:6

    Topics: Aspergillus niger; beta-Glucosidase; Cloning, Molecular; Genes, Fungal; Introns; Iridoids; Pichia

2019
Role of intestinal microbiota-mediated genipin dialdehyde intermediate formation in geniposide-induced hepatotoxicity in rats.
    Toxicology and applied pharmacology, 2019, 08-15, Volume: 377

    Topics: Aldehydes; Amino Acids; Animals; Anti-Bacterial Agents; beta-Glucosidase; Bile; Chemical and Drug Induced Liver Injury; Gastrointestinal Microbiome; Glutathione; Glycoside Hydrolases; Iridoids; Liver; Lysine; Male; Rats; Rats, Sprague-Dawley

2019
Screening of the Hepatotoxic Components in
    Molecules (Basel, Switzerland), 2019, Oct-30, Volume: 24, Issue:21

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Gardenia; Inflammation; Iridoids; Liver; Molecular Docking Simulation; Oxidative Stress; Phytochemicals; Plant Extracts; Rats; Receptors, Tumor Necrosis Factor, Type I; Reference Standards

2019
Effect of genipin-1-β-d-gentiobioside on diabetic nephropathy in mice by activating AMP-activated protein kinase/silencing information regulator-related enzyme 1/ nuclear factor-κB pathway.
    The Journal of pharmacy and pharmacology, 2021, Aug-12, Volume: 73, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gardenia; Inflammation; Iridoids; Kidney; Male; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phytotherapy; Plant Extracts; Podocytes; Sirtuin 1

2021
Metabolomics based comprehensive investigation of Gardeniae Fructus induced hepatotoxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 153

    Topics: Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Fruit; Gardenia; Hep G2 Cells; Humans; Iridoids; Plant Extracts; Rats; Rats, Sprague-Dawley

2021
Glutathione S-Transferases Mediate In Vitro and In Vivo Inactivation of Genipin: Implications for an Underlying Detoxification Mechanism.
    Journal of agricultural and food chemistry, 2023, Feb-08, Volume: 71, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Transferase; Liver; Rats; Sulfhydryl Compounds

2023
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