Page last updated: 2024-08-24

gemcitabine and rx-3117

gemcitabine has been researched along with rx-3117 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahn, CH; Alexander, V; Chandra, G; Choi, WJ; Chung, HJ; Jeong, LS; Kim, HO; Kim, JH; Lee, HW; Lee, SK; Lee, YB; Majik, MS; Nayak, A; Zhao, LX1
Ahn, CH; Fine, T; Kashi, R; Kaye, J; Kim, DJ; Lee, YB; Ohne, O; Peters, GJ; Smid, K; Yang, MY1
Honeywell, RJ; Kathmann, I; Kristensen, MH; Peters, GJ; Sarkisjan, D1
Balboni, B; Benaim, E; El Hassouni, B; Giovannetti, E; Heaton, C; Honeywell, RJ; Kim, DJ; Lee, YB; Peters, GJ; Peterson, C; Poore, J; Sarkisjan, D1

Reviews

1 review(s) available for gemcitabine and rx-3117

ArticleYear
RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment.
    Expert opinion on investigational drugs, 2019, Volume: 28, Issue:4

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms; Patient Selection

2019

Other Studies

3 other study(ies) available for gemcitabine and rx-3117

ArticleYear
Fluorocyclopentenyl-cytosine with broad spectrum and potent antitumor activity.
    Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cyclopentanes; Cytosine; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Xenograft Model Antitumor Assays

2012
A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytidine; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gemcitabine; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Xenograft Model Antitumor Assays

2014
Sensitive liquid chromatography mass spectrometry (LC-MS) assay reveals novel insights on DNA methylation and incorporation of gemcitabine, its metabolite difluorodeoxyuridine, deoxyuridine, and RX-3117 into DNA.
    Nucleosides, nucleotides & nucleic acids, 2016, Volume: 35, Issue:10-12

    Topics: Cell Line, Tumor; Chromatography, Liquid; Cytidine; Deoxycytidine; DNA; DNA Methylation; Floxuridine; Gemcitabine; Humans; Limit of Detection; Mass Spectrometry; RNA

2016