Page last updated: 2024-08-24

gemcitabine and emodin

gemcitabine has been researched along with emodin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL1
Chen, Y; Guo, Q; Kang, M; Wu, Y; Xie, Q; Zhang, B1
Chen, H; Guo, Y; Lin, S; Liu, A; Liu, J; Tan, W; Tong, H; Wang, Z; Wei, W1
Chen, H; Guo, H; Guo, Y; Lin, S; Liu, D; Wei, W1
Hu, YS; Ke, PY; Lin, SZ; Liu, A; Tang, LL; Wang, ZH1
Liu, A; Tong, HF; Zeng, Y1
Chen, H; Guo, HC; Lin, SZ; Liu, HB; Liu, JX; Ni, ZL; Tan, W; Tong, HF; Wang, ZH; Wei, WT1
Bu, H; Chen, H; Guo, HC; Li, H; Lin, SZ; Liu, DL; Liu, HB; Ni, ZL; Tong, HF; Wang, ZH1
Bu, HQ; Chen, H; Guo, HC; Li, HH; Li, W; Lin, SZ; Liu, DL; Luo, J; Tong, HF; Wang, ZH; Wei, WT; Wu, HY; Zuo, MM1
Liu, A; Luo, J; Zhang, JH1
Chen, H; Chen, KJ; Li, H; Li, Y; Lin, SZ; Liu, DL; Luo, J; Tong, HF; Zhang, JH; Zhang, W1

Reviews

1 review(s) available for gemcitabine and emodin

ArticleYear
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
    Medicinal research reviews, 2021, Volume: 41, Issue:1

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization

2021

Other Studies

10 other study(ies) available for gemcitabine and emodin

ArticleYear
Potentiation of the effect of gemcitabine by emodin in pancreatic cancer is associated with survivin inhibition.
    Biochemical pharmacology, 2009, Jun-01, Volume: 77, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Caspase 3; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Deoxycytidine; DNA Primers; Drug Synergism; Emodin; Gemcitabine; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Muscle, Skeletal; Pancreatic Neoplasms; Rats; Reverse Transcriptase Polymerase Chain Reaction; Suppression, Genetic; Survivin

2009
Enhanced effect of gemcitabine by emodin against pancreatic cancer in vivo via cytochrome C-regulated apoptosis.
    Oncology reports, 2011, Volume: 25, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Deoxycytidine; Drug Synergism; Emodin; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Xenograft Model Antitumor Assays

2011
[Emodin enhances antitumor effect of gemcitabine in model of SW1990 cell xenograft on athymic mouse].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochromes c; Deoxycytidine; Drug Synergism; Emodin; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Tumor Burden; Xenograft Model Antitumor Assays

2010
[Role of nuclear factor-kappaB on emodin-induced sensitization of pancreatic cancer to gemcitabine].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Resistance, Neoplasm; Emodin; Female; Gemcitabine; Humans; Inhibitor of Apoptosis Proteins; Ki-67 Antigen; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; NF-kappa B; Pancreatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Survivin; Tumor Burden

2011
[Effect of emodin combined gemcitabine on the growth and apoptosis of pancreatic cancer cell line BxPC-3 in vitro].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2011, Volume: 31, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Emodin; Gemcitabine; Humans; Pancreatic Neoplasms

2011
Enhanced antitumor efficacy by the combination of emodin and gemcitabine against human pancreatic cancer cells via downregulation of the expression of XIAP in vitro and in vivo.
    International journal of oncology, 2011, Volume: 39, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Down-Regulation; Drug Synergism; Emodin; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Tumor Burden; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays

2011
Emodin reverses gemcitabine resistance in pancreatic cancer cells via the mitochondrial apoptosis pathway in vitro.
    International journal of oncology, 2012, Volume: 40, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; Emodin; Gemcitabine; Humans; Mitochondria; Pancreatic Neoplasms; Protein Kinase Inhibitors

2012
Emodin potentiates the antitumor effects of gemcitabine in PANC-1 pancreatic cancer xenograft model in vivo via inhibition of inhibitors of apoptosis.
    International journal of oncology, 2012, Volume: 40, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Deoxycytidine; Down-Regulation; Drug Synergism; Emodin; Gemcitabine; Humans; Inhibitor of Apoptosis Proteins; Ki-67 Antigen; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Survivin; Tumor Burden; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays

2012
[Emodin combined gemcitabine inhibited the growth of pancreatic cancer in vitro and in vivo and its mechanisms study].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2012, Volume: 32, Issue:5

    Topics: Animals; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Emodin; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Xenograft Model Antitumor Assays

2012
Emodin sensitizes the gemcitabine-resistant cell line Bxpc-3/Gem to gemcitabine via downregulation of NF-κB and its regulated targets.
    International journal of oncology, 2013, Volume: 42, Issue:4

    Topics: Antimetabolites, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Shape; Deoxycytidine; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Emodin; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; NF-kappa B; Protein Binding; Survivin; X-Linked Inhibitor of Apoptosis Protein

2013