fosfedil has been researched along with thiazoles in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (81.48) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glossmann, H; Knaus, HG; Staudinger, R | 1 |
| Goto, K; Kohno, T; Morita, T; Tsukamoto, G; Yoshino, K | 1 |
| Goto, K; Morita, T; Tsukamoto, G; Yoshiizumi, K; Yoshino, K | 1 |
| Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
| Kohno, T; Morita, T; Tsukamoto, G; Yoshino, K | 1 |
| Chiarini, A; da Re, P; Fabbri, G; Valenti, P | 1 |
| Lucchesi, BR; Lynch, JJ; Montgomery, DG | 1 |
| Gross, GJ; Pelc, LR; Warltier, DC | 2 |
| Bowles, MJ; Khurmi, NS; Lahiri, A; O'Hara, MJ; Raftery, EB | 1 |
| Iijima, T; Morita, T; Taira, N | 1 |
| Fischli, W; Hengartner, U; Holck, M | 1 |
| Thomas, EW | 1 |
| Lucchesi, BR; Lynch, JJ; Montgomery, DG; Patterson, E | 1 |
| Bopp, BA; Thomas, EW | 1 |
| Nose, T; Sotomura, M; Tanaka, A; Tanaka, H; Tsunetoshi, Y | 1 |
| Ito, K; Kanazawa, T; Morita, T; Nose, T; Yoshino, K | 1 |
| Ito, K; Kanazawa, T; Morita, T; Nose, T | 2 |
| Ito, K; Morita, T; Nose, T | 1 |
| Ito, K; Morita, T; Nose, T; Sukamoto, T; Yoshidomi, M | 1 |
| Fukuda, T; Hamada, Y; Ikeda, Y; Ito, K; Kanazawa, T; Kawakami, K; Kitamura, H; Morimoto, Y; Morita, T; Nose, T; Sato, I; Sukamoto, T; Tajima, S | 1 |
| Hirakawa, K; Iino, T; Nose, T; Ogino, F; Takebe, H; Unno, T | 3 |
| Baziard-Mouysset, G; Bonnafous, R; Payard, M; Stigliani, JL; Tchani, G; Tisne-Versailles, J | 1 |
| Hirakawa, N; Kashiwaba, N; Kutsuma, T; Matsumoto, H; Sekine, A; Sekine, Y; Yamaura, T | 1 |
1 trial(s) available for fosfedil and thiazoles
| Article | Year |
|---|---|
Ambulatory monitoring and exercise testing in the evaluation of a new long-acting calcium ion antagonist KB-944 (Fostedil) for the treatment of exertional angina pectoris.
Topics: Adult; Aged; Ambulatory Care; Angina Pectoris; Benzothiazoles; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Thiazoles | 1985 |
26 other study(ies) available for fosfedil and thiazoles
| Article | Year |
|---|---|
Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140.
Topics: Alkaloids; Allosteric Regulation; Animals; Benzothiazoles; Benzylisoquinolines; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; Diltiazem; Guinea Pigs; Isomerism; Isradipine; Kinetics; Macromolecular Substances; Models, Theoretical; Muscles; Oxadiazoles; Pyridines; Pyrrolidines; Rabbits; Thiazoles; Verapamil | 1991 |
Organic phosphorus compounds. IV. Asymmetric 4-(benzothiazol-2-yl)benzylphosphonates as potent calcium antagonistic vasodilators.
Topics: Animals; Benzothiazoles; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Coronary Circulation; Dogs; Guinea Pigs; In Vitro Techniques; Male; Organophosphorus Compounds; Thiazoles; Vasodilator Agents | 1990 |
Organic phosphorus compounds. 5. (4-Benzothiazol-2-ylbenzyl)amidophosphonate as potent calcium antagonistic vasodilators.
Topics: Animals; Benzothiazoles; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Coronary Circulation; Coronary Vessels; Dogs; Guinea Pigs; Male; Molecular Structure; Organophosphorus Compounds; Pyrrolidines; Structure-Activity Relationship; Thiazoles; Vasodilation; Vasodilator Agents | 1990 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Organic phosphorus compounds. 2. Synthesis and coronary vasodilator activity of (benzothiazolylbenzyl) phosphonate derivatives.
Topics: Allosteric Site; Animals; Benzothiazoles; Chemical Phenomena; Chemistry; Coronary Circulation; Guinea Pigs; Heart; In Vitro Techniques; Male; Thiazoles; Vasodilator Agents | 1989 |
Chromosome and xanthone derivatives related to Fostedil.
Topics: Animals; Benzothiazoles; Calcium Channel Blockers; Chromones; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Thiazoles; Xanthenes | 1987 |
The effects of calcium entry blockade on the vulnerability of infarcted canine myocardium toward ventricular fibrillation.
Topics: Animals; Benzothiazoles; Bepridil; Calcium Channel Blockers; Diltiazem; Dogs; Electrocardiography; Electrophysiology; Heart; Heart Rate; Male; Myocardial Infarction; Pyrrolidines; Thiazoles; Ventricular Fibrillation | 1986 |
Effects of KB-944, a novel calcium antagonist, in several models of canine myocardial ischemia.
Topics: Animals; Benzothiazoles; Blood Pressure; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Female; Heart Rate; Male; Mathematics; Phenylephrine; Regional Blood Flow; Thiazoles | 1986 |
Effects of a new calcium entry blocking agent, KB-944, on the membrane potential and currents of mammalian ventricular muscle cells.
Topics: Action Potentials; Animals; Benzothiazoles; Calcium Channel Blockers; Dogs; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Thiazoles | 1985 |
Cardiac and systemic hemodynamic actions of the slow channel calcium blocking agent, KB-944.
Topics: Animals; Benzothiazoles; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Diastole; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; Myocardium; Oxygen Consumption; Systole; Thiazoles; Vascular Resistance; Vasodilation | 1985 |
Effects of temperature and allosteric modulators on [3H] nitrendipine binding: methods for detecting potential Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Animals; Benzothiazoles; Binding Sites; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Microsomes; Myocardium; Nifedipine; Nitrendipine; Propylamines; Temperature; Thiazoles; Tiapamil Hydrochloride; Verapamil | 1984 |
High-performance liquid chromatographic determination of a new calcium antagonist, fostedil, in plasma and urine using fluorescence detection.
Topics: Animals; Benzothiazoles; Chromatography, High Pressure Liquid; Dogs; Spectrometry, Fluorescence; Thiazoles | 1984 |
Cardiac electrophysiologic actions of KB-944 (Fostedil), a new calcium antagonist, in the anesthetized dog.
Topics: Animals; Atrioventricular Node; Benzothiazoles; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Electric Conductivity; Electrocardiography; Electrophysiology; Glucagon; Heart Conduction System; Heart Rate; Male; Propranolol; Sinoatrial Node; Thiazoles; Time Factors | 1984 |
Pharmacokinetics of fostedil, a new calcium antagonist, in beagle dogs following oral and intravenous administration.
Topics: Administration, Oral; Animals; Benzothiazoles; Calcium Channel Blockers; Capsules; Dogs; Female; Half-Life; Injections, Intravenous; Kinetics; Male; Protein Binding; Solutions; Suspensions; Thiazoles | 1984 |
Mutagenicity evaluation of KB-944, a new calcium antagonist, in the Ames bacterial system.
Topics: Benzothiazoles; Calcium Channel Blockers; Escherichia coli; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Thiazoles; Tryptophan | 1982 |
Vasodilator action of KB-944, a new calcium antagonist.
Topics: Anesthesia; Animals; Benzothiazoles; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Dogs; Guinea Pigs; Heart Rate; Male; Papaverine; Thiazoles; Time Factors; Vasodilator Agents | 1982 |
Vasodilator mechanism of KB-944, a new calcium antagonist.
Topics: Adenosine; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Chloride; Coronary Vessels; Diltiazem; Dogs; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium; Rabbits; Thiazoles; Vasodilator Agents; Verapamil | 1982 |
Antihypertensive effect of KB-944, a new calcium antagonist, in conscious normotensive and hypertensive rats.
Topics: Animals; Antihypertensive Agents; Benzothiazoles; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Diltiazem; Heart Rate; Hypertension; Hypertension, Renal; Nifedipine; Rats; Thiazoles | 1982 |
Cardiac action of KB-944, a new calcium antagonist.
Topics: Anesthesia; Animals; Benzothiazoles; Calcium Channel Blockers; Coronary Circulation; Dogs; Guinea Pigs; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Myocardial Contraction; Myocardium; Oxygen Consumption; Thiazoles | 1982 |
Antiarrhythmic effect of KB-944, a new calcium antagonist. A comparison with verapamil and diltiazem.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Benzothiazoles; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Epinephrine; Guinea Pigs; Male; Ouabain; Rats; Thiazoles; Verapamil | 1982 |
General pharmacology of KB-944, a new calcium antagonist.
Topics: Anesthesia; Animals; Anticonvulsants; Autonomic Nervous System; Benzothiazoles; Body Temperature; Calcium Channel Blockers; Cats; Digestive System; Drug Synergism; Female; Guinea Pigs; Male; Motor Activity; Motor Neurons; Muscle Relaxants, Central; Muscle, Smooth; Rats; Rats, Inbred Strains; Reflex; Thiazoles | 1982 |
Acute toxicity study of KB-944, a new calcium antagonist.
Topics: Animals; Benzothiazoles; Calcium Channel Blockers; Lethal Dose 50; Mice; Mice, Inbred ICR; Rats; Species Specificity; Thiazoles | 1982 |
1-month subacute oral toxicity study of KB-944, a new calcium antagonist, in rats.
Topics: Animals; Benzothiazoles; Blood; Blood Cell Count; Blood Chemical Analysis; Body Weight; Calcium Channel Blockers; Drinking; Eating; Enzymes; Female; Male; Organ Size; Rats; Thiazoles; Time Factors | 1982 |
1-month subacute oral toxicity study of KB-944, a new calcium antagonist, in beagles.
Topics: Animals; Benzothiazoles; Blood; Blood Cell Count; Blood Chemical Analysis; Body Weight; Calcium Channel Blockers; Dogs; Drinking; Eating; Electrocardiography; Female; Male; Organ Size; Thiazoles; Urine | 1982 |
Influence of the vinyl group on the calcium antagonistic activity of analogues of Fostedil.
Topics: Animals; Aorta, Thoracic; Benzothiazoles; Calcium Channel Blockers; In Vitro Techniques; Muscle Contraction; Rabbits; Thiazoles; Vinyl Compounds | 1994 |
A novel histamine 2(H2) receptor antagonist with gastroprotective activity. I. Synthesis and pharmacological evaluation of N-phenoxypropylacetamide derivatives with thioether function.
Topics: Acetamides; Administration, Oral; Animals; Anti-Ulcer Agents; Benzothiazoles; Calcium Channel Blockers; Gastric Acid; Histamine H2 Antagonists; Male; Perfusion; Piperidines; Rats; Rats, Wistar; Stomach; Structure-Activity Relationship; Sulfides; Thiazoles | 1998 |