Page last updated: 2024-08-17

folic acid and leucine

folic acid has been researched along with leucine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199026 (65.00)18.7374
1990's1 (2.50)18.2507
2000's7 (17.50)29.6817
2010's3 (7.50)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Lietman, PS; Rogers, HJ1
Ammon, HV; Phillips, SF; Thomas, PJ1
Fry, DW; Goldman, ID; White, JC1
Lorenzo, AV; Spector, R; Welch, K1
Spector, R1
Harrap, KR; Jackson, RC; Taylor, GA1
Saunders, J; Wickramasinghe, SN; Williams, G1
Corcino, JJ; Klipstein, FA1
Anderson, R; Jackson, N1
Appleman, JR; Blakley, RL; Delcamp, TJ; Freisheim, JH; Prendergast, NJ1
Said, HM; Strum, WB1
MacKinney, AA; Vas, R1
Donohoe, JA; Hickie, JB; Kolos, G; Williams, JF1
Frank, W1
Herbert, V; Momtazi, S1
Viñuela, E1
Leslie, GI; Rowe, PB1
Littlefield, JW; Nakamura, H1
Berg, NO; Dahlqvist, A; Lindberg, T; Nordén, A1
Cattaneo, C; Gradnik, B; Malcovati, M1
Evans, EA1
Bond, AN; Okany, CC; Wickramasinghe, SN1
Blair, JA; Lucas, ML; Swanston-Flatt, SK1
Barczak, AK; Coyle, JT; Luthi-Carter, R; Speno, H1
Brent, RL; Fawcett, LB; Pugarelli, JE1
Finer-Moore, JS; Fritz, TA; Liu, L; Stroud, RM1
BROCKMAN, RW1
RIEDER, RF; WEATHERALL, DJ1
Bailey, LB; Coats, BS; Davis, SR; Gregory, JF; Kick, LS; Quinlivan, EP; Shane, B; Stacpoole, PW; Williamson, J1
Bailey, LB; Capdevila, A; Coats, BS; Davis, SR; Ghandour, H; Gregory, JF; Quinlivan, EP; Selhub, J; Shane, B; Shelnutt, KP; Shuster, JJ; Stacpoole, PW; Wagner, C1
Chinkes, DL; Herndon, DN; Zhang, XJ1
Gilbert, LR; Gregory, JF; Lamers, Y; Stacpoole, PW; Williamson, J1
KARNOFSKY, DA; PATTERSON, PA; RIDGWAY, LP1
Amighi, K; Langer, I; Mathieu, V; Mathivet, T; Rosière, R; Van Woensel, M; Vermeersch, M; Wauthoz, N1
Ducker, GS; Gitai, Z; Li, SH; Mayer, JA; Morscher, RJ; Rabinowitz, JD; Sperl, W1
Bhatt, JD; Chudasama, CJ; Dixit, BC; Dixit, RB; Patel, BD; Patel, TS1
Bodinier, R; Cosson, P; Guilhen, C; Iwade, Y; Jauslin, TN; Kawata, T; Lamrabet, O; Leiba, J; Lima, WC; Marchetti, A; Sabra, A1
Hou, L; Shi, W; Song, Z; Wu, Y; Xu, Z1
Agarwal, M; Ambreen, H; Budhwar, R; Goel, S; Jagannath, A; Katiyar-Agarwal, S; Kumar, A; Oraon, PK; Satyawada, RR; Shukla, RN; Wahlang, DR1

Reviews

1 review(s) available for folic acid and leucine

ArticleYear
MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS.
    Advances in cancer research, 1963, Volume: 7

    Topics: Alkylating Agents; Antineoplastic Agents; Azaserine; Dactinomycin; DNA; Drug Resistance; Drug Resistance, Microbial; Drug Tolerance; Folic Acid; Humans; Leucine; Metabolism; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; RNA; Steroids; Tissue Culture Techniques

1963

Trials

1 trial(s) available for folic acid and leucine

ArticleYear
Glycine turnover and decarboxylation rate quantified in healthy men and women using primed, constant infusions of [1,2-(13)C2]glycine and [(2)H3]leucine.
    The Journal of nutrition, 2007, Volume: 137, Issue:12

    Topics: Adult; Carbon Isotopes; Decarboxylation; Female; Folic Acid; Glycine; Humans; Isotope Labeling; Leucine; Male; Pyridoxal Phosphate; Tritium; Vitamin B 12

2007

Other Studies

38 other study(ies) available for folic acid and leucine

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
The in vitro effect of trimethoprim on blastogenic transformation of human peripheral blood lymphocytes.
    Biochemical pharmacology, 1977, Sep-01, Volume: 26, Issue:17

    Topics: Autoradiography; Cells, Cultured; Concanavalin A; Deoxyuridine; Folic Acid; Formates; Humans; In Vitro Techniques; Leucine; Leucovorin; Lymphocyte Activation; Lymphocytes; Thymidine; Time Factors; Trimethoprim; Uridine

1977
Effects of long chain fatty acids on solute absorption: perfusion studies in the human jejunum.
    Gut, 1977, Volume: 18, Issue:10

    Topics: Betaine; Bile Acids and Salts; Biological Transport; Fatty Acids, Unsaturated; Folic Acid; Glucose; Glycerides; Humans; Jejunum; Leucine; Mannitol; Oleic Acids; Perfusion; Ricinoleic Acids; Water-Electrolyte Balance; Xylose

1977
Rapid separation of low molecular weight solutes from liposomes without dilution.
    Analytical biochemistry, 1978, Oct-15, Volume: 90, Issue:2

    Topics: Chromatography, Gel; Folic Acid; Inulin; Leucine; Liposomes; Methionine; Methotrexate; Sucrose; Thymidine

1978
Accumulation of materials by a papilloma of the choroid plexus in vitro.
    Developmental medicine and child neurology, 1977, Volume: 19, Issue:3

    Topics: Cerebral Ventricle Neoplasms; Choroid Plexus; Culture Techniques; Folic Acid; Humans; Infant, Newborn; Inositol; Iodides; Leucine; Male; Papilloma; Penicillins

1977
The effect of pronase on choroid plexus transport.
    Brain research, 1977, Oct-14, Volume: 134, Issue:3

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Choroid Plexus; Deoxyglucose; Folic Acid; In Vitro Techniques; Inositol; Iodides; L-Lactate Dehydrogenase; Leucine; Pronase; Rabbits; Stereoisomerism

1977
Aspects of the biochemical pharmacology of cytembena.
    Neoplasma, 1975, Volume: 22, Issue:3

    Topics: Acrylates; Animals; Cell Division; DNA Nucleotidyltransferases; DNA, Neoplasm; Dose-Response Relationship, Drug; Folic Acid; Formate-Tetrahydrofolate Ligase; Glycine Hydroxymethyltransferase; Humans; In Vitro Techniques; Leucine; Leucovorin; Leukemia L1210; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Rats; Sarcoma, Yoshida; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidine; Thymidine Kinase; Thymidylate Synthase; Uridine

1975
Effects of anticonvulsant drugs on the synthesis of DNA and protein by human bone marrow cells in vitro.
    Scandinavian journal of haematology, 1976, Volume: 17, Issue:4

    Topics: Bone Marrow; Bone Marrow Cells; DNA; Folic Acid; Humans; Leucine; Leucovorin; Phenobarbital; Phenytoin; Protein Biosynthesis; Thymidine

1976
Malabsorption of essential amino acids in tropical sprue.
    Gastroenterology, 1975, Volume: 68, Issue:2

    Topics: Administration, Oral; Adult; Aged; Amino Acids, Essential; Fats; Feces; Folic Acid; Humans; Intestinal Absorption; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Serum Albumin; Sprue, Tropical; Tetracycline; Threonine; Valine; Vitamin B 12; Xylose

1975
A study on the effect of folate deficiency on the incorporation of 14-C labelled glycine, serine and leucine into the oviduct protein of the oestrogen-treated, immature female domestic fowl.
    The International journal of biochemistry, 1975, Volume: 6, Issue:1

    Topics: Animals; Chickens; Estradiol; Female; Folic Acid; Folic Acid Deficiency; Glycine; Leucine; Organ Size; Oviducts; Protein Biosynthesis; Serine; Time Factors

1975
Effects of conversion of phenylalanine-31 to leucine on the function of human dihydrofolate reductase.
    Biochemistry, 1989, May-30, Volume: 28, Issue:11

    Topics: Binding Sites; Folic Acid; Humans; Kinetics; Leucine; Methotrexate; Mutation; NADP; Phenylalanine; Recombinant Proteins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Trimethoprim; X-Ray Diffraction

1989
Effect of ethanol and other aliphatic alcohols on the intestinal transport of folates.
    Digestion, 1986, Volume: 35, Issue:3

    Topics: Alcohols; Animals; Biological Transport, Active; Ethanol; Folic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Jejunum; Leucine; Male; Rats; Rats, Inbred Strains; Tetrahydrofolates

1986
The assay of diphenylhydantoin effects on growing human lymphocytes.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Anticonvulsants; Carbon Isotopes; DNA; Folic Acid; Folic Acid Antagonists; Growth; Humans; Leucine; Leukocytes; Lymphocytes; Phenytoin; Phosphorus Isotopes; Potassium; Sodium; Thymidine; Tritium

1973
The action of orotic acid as a positive inotropic agent during the acute phase of myocardial hypertrophy.
    Australian and New Zealand journal of medicine, 1974, Volume: 4, Issue:6

    Topics: Acute Disease; Animals; Cardiomegaly; Folic Acid; Leucine; Male; Myocardial Contraction; Myocardium; Orotic Acid; Protein Biosynthesis; Rats; Stimulation, Chemical; Uridine; Vitamin B 12

1974
[On the influence of RNA and protein synthesis in ascites cells].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1967, Volume: 22, Issue:3

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Arginase; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Dactinomycin; Folic Acid; Glycerolphosphate Dehydrogenase; Histones; In Vitro Techniques; L-Lactate Dehydrogenase; Leucine; Neoplasm Proteins; Protamines; Rats; Ribonucleases; RNA, Neoplasm; Tritium; Uridine

1967
Intestinal absorption using vibration-obtained individual small bowel epithelial cells of the rat: folate absorption.
    The American journal of clinical nutrition, 1973, Volume: 26, Issue:1

    Topics: Animals; Epithelial Cells; Epithelium; Folic Acid; Glucose; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Male; Methods; Phenytoin; Rats; Tritium; Vibration

1973
Virus-specific proteins in Escherichia coli infected with the RNA bacteriophage MS2.
    Bulletin de la Societe de chimie biologique, 1968, Volume: 50, Issue:12

    Topics: Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Dactinomycin; Detergents; Electrophoresis; Escherichia coli; Eukaryota; Folic Acid; Genetic Code; Histidine; Kinetics; Leucine; Methionine; Molecular Weight; Peptides; Protoplasts; RNA, Viral; Tritium; Uracil; Viral Proteins; Virus Replication

1968
Folate binding by the brush border membrane proteins of small intestinal epithelial cells.
    Biochemistry, 1972, Apr-25, Volume: 11, Issue:9

    Topics: Amino Acids; Animals; Carbon Isotopes; Carrier Proteins; Cell Fractionation; Cell Membrane; Chromatography, Gel; Dansyl Compounds; Electrophoresis; Epithelial Cells; Epithelium; Female; Folic Acid; Intestine, Small; Leucine; Macromolecular Substances; Molecular Weight; Protein Binding; Proteins; Rats; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Tritium

1972
Purification, properties, and synthesis of dihydrofolate reductase from wild type and methotrexate-resistant hamster cells.
    The Journal of biological chemistry, 1972, Jan-10, Volume: 247, Issue:1

    Topics: Animals; Antigens; Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Chromatography, Affinity; Cricetinae; Drug Resistance; Electrophoresis; Folic Acid; Hydrogen-Ion Concentration; Immune Sera; Immunoelectrophoresis; Kidney; Kinetics; Leucine; Methotrexate; Molecular Weight; Rabbits; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tritium; Ultracentrifugation

1972
Intestinal dipeptidases and disaccharidases in celiac disease in adults.
    Gastroenterology, 1970, Volume: 59, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acids; Celiac Disease; Diet Therapy; Dipeptidases; Dipeptides; Feces; Female; Folic Acid; Galactosidases; Glucosidases; Glutamates; Glutens; Glycoside Hydrolases; Humans; Intestinal Mucosa; Leucine; Lipids; Male; Middle Aged; Proline; Sucrase; Valine; Xylose

1970
[Effect of a hemopoietic phosphocreatinine-vitamin combination on the protein synthesis in the regenerated rat liver].
    Il Farmaco; edizione pratica, 1969, Volume: 24, Issue:1

    Topics: Animals; Female; Folic Acid; Leucine; Liver; Liver Regeneration; Phosphocreatine; Protein Biosynthesis; Pyridoxine; Rats; Vitamin B 12

1969
Control of self-irradiation decomposition of tritium-labelled compounds at high specific activity.
    Nature, 1966, Jan-08, Volume: 209, Issue:5019

    Topics: Alcohols; Drug Stability; Ethanol; Folic Acid; Formates; Histidine; Leucine; Methotrexate; Nucleosides; Penicillin G; Radiation-Protective Agents; Thymidine; Tritium; Tyrosine; Uridine

1966
Effects of ethanol on cell volume and protein synthesis in a human lymphoblastoid cell line (Raji).
    Acta haematologica, 1983, Volume: 70, Issue:1

    Topics: Cell Count; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Erythrocyte Indices; Ethanol; Folic Acid; Leucine; Leucovorin; Models, Biological; Protein Biosynthesis

1983
Intestinal folic acid absorption and the acid microclimate. The effects of compounds relevant to folate malabsorption.
    Pflugers Archiv : European journal of physiology, 1981, Volume: 392, Issue:1

    Topics: Animals; Ethanol; Folic Acid; Folic Acid Deficiency; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Jejunum; Leucine; Malabsorption Syndromes; Methotrexate; Phenytoin; Rats

1981
Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II.
    Brain research, 1998, Jun-08, Volume: 795, Issue:1-2

    Topics: Animals; Antigens, Surface; Binding, Competitive; Carboxypeptidases; Chelating Agents; Cloning, Molecular; Cobalt; Coumarins; Dipeptides; Edetic Acid; Folic Acid; Glutamate Carboxypeptidase II; Histamine H1 Antagonists; Humans; Hydrolysis; Isocoumarins; Kinetics; Leucine; Male; Neuropeptides; Pepstatins; Phenanthrolines; Prostatic Neoplasms; Protease Inhibitors; Rats; Serine Proteinase Inhibitors; Substrate Specificity; Synaptic Transmission; Tumor Cells, Cultured

1998
Effects of supplemental methionine on antiserum-induced dysmorphology in rat embryos cultured in vitro.
    Teratology, 2000, Volume: 61, Issue:5

    Topics: Animals; Congenital Abnormalities; Culture Techniques; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Folic Acid; Immune Sera; Lethal Dose 50; Leucine; Maternal Exposure; Methionine; Rats; Rats, Wistar; Yolk Sac

2000
Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access.
    Biochemistry, 2002, Jun-04, Volume: 41, Issue:22

    Topics: Binding Sites; Biological Transport; Deoxyuracil Nucleotides; Escherichia coli; Folic Acid; Leucine; Models, Chemical; Point Mutation; Protons; Quinazolines; Tetrahydrofolates; Thymidylate Synthase; Tryptophan

2002
STUDIES ON HEMOGLOBIN BIOSYNTHESIS: ASYNCHRONOUS SYNTHESIS OF HEMOGLOBIN A AND HEMOGLOBIN A2 BY ERYTHROCYTE PRECURSORS.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Anemia; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Pernicious; Anemia, Sickle Cell; Blood Protein Electrophoresis; Bone Marrow; Chromatography; Folic Acid; Folic Acid Deficiency; Hemoglobin A2; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Iron; Iron Isotopes; Leucine; Metabolic Diseases; Primary Myelofibrosis; Proteins; Pyruvate Kinase; Reticulocytes; Spherocytosis, Hereditary; Thalassemia; Vitamin B Deficiency

1965
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 286, Issue:2

    Topics: Adult; Carbon; Carbon Isotopes; Female; Folic Acid; Homocysteine; Humans; Leucine; Methionine; Methylation; Reference Values; Serine

2004
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
    The Journal of nutrition, 2005, Volume: 135, Issue:5

    Topics: Adult; Amino Acids; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Leucine; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Serine

2005
Folate stimulation of wound DNA synthesis.
    The Journal of surgical research, 2008, Jun-01, Volume: 147, Issue:1

    Topics: Amino Acids; Animals; DNA; Enteral Nutrition; Folic Acid; Leucine; Male; Rabbits; Wound Healing

2008
Effect of folic acid, 4-amino folic acids and related substances on growth of chick embryo.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1949, Volume: 71, Issue:3

    Topics: Folic Acid; Growth; Humans; Isoleucine; Leucine; Valine; Vitamin B Complex; Vitamins

1949
Development and evaluation of well-tolerated and tumor-penetrating polymeric micelle-based dry powders for inhaled anti-cancer chemotherapy.
    International journal of pharmaceutics, 2016, Mar-30, Volume: 501, Issue:1-2

    Topics: Administration, Inhalation; Animals; Antineoplastic Agents, Phytogenic; Bronchoalveolar Lavage Fluid; Cell Count; Cell Line, Tumor; Cell Survival; Cytokines; Dextrans; Drug Liberation; Female; Folic Acid; Humans; Leucine; Lung Neoplasms; Mannitol; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols; Powders

2016
Mitochondrial translation requires folate-dependent tRNA methylation.
    Nature, 2018, 02-01, Volume: 554, Issue:7690

    Topics: Aminohydrolases; Biocatalysis; Carrier Proteins; Codon; Electron Transport; Folic Acid; Folic Acid Antagonists; Glycine Hydroxymethyltransferase; GTP-Binding Proteins; Guanosine; HCT116 Cells; HEK293 Cells; Humans; Leucine; Lysine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; Oxidative Phosphorylation; Protein Biosynthesis; Ribosomes; RNA-Binding Proteins; RNA, Transfer; Sarcosine; Tetrahydrofolates; Thymine Nucleotides

2018
Design and synthesis of leucine-linked quinazoline-4(3H)-one-sulphonamide molecules distorting malarial reductase activity in the folate pathway.
    Archiv der Pharmazie, 2019, Volume: 352, Issue:9

    Topics: Animals; Antimalarials; Cell Survival; Chlorocebus aethiops; Drug Design; Folic Acid; Folic Acid Antagonists; Inhibitory Concentration 50; Leucine; Molecular Docking Simulation; Molecular Structure; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Quinazolines; Sulfonamides; Vero Cells

2019
LrrkA, a kinase with leucine-rich repeats, links folate sensing with Kil2 activity and intracellular killing.
    Cellular microbiology, 2020, Volume: 22, Issue:1

    Topics: Dictyostelium; Folic Acid; Gene Expression Regulation, Bacterial; Intracellular Space; Klebsiella pneumoniae; Leucine; Phagocytosis; Phagosomes; Phosphotransferases; Protein Domains; Protozoan Proteins; Signal Transduction

2020
Folate-Mediated Targeted Delivery of siPLK1 by Leucine-Bearing Polyethylenimine.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: A549 Cells; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Folic Acid; Gene Silencing; Gene Transfer Techniques; Genetic Therapy; Humans; Leucine; Nanoparticles; Polo-Like Kinase 1; Polyethyleneimine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Stomach Neoplasms

2020
Long-read-based draft genome sequence of Indian black gram IPU-94-1 'Uttara': Insights into disease resistance and seed storage protein genes.
    The plant genome, 2022, Volume: 15, Issue:3

    Topics: Disease Resistance; Folic Acid; Iron; Leucine; Nucleotides; Plant Breeding; Seed Storage Proteins; Sequence Analysis, DNA; Vigna

2022
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