fluorouracil and dinoprostone

fluorouracil has been researched along with dinoprostone in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's3 (10.00)18.2507
2000's10 (33.33)29.6817
2010's11 (36.67)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Tsuchiya, A; Yamamoto, T1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Lees, P; Sedgwick, AD1
Bradley, TR; Hodgson, GS; Kriegler, AB1
Fukumoto, M; Ishikawa, T; Kadokura, M; Okonogi, H; Sakaba, H; Shimizu, H; Suzuki, Y1
Hamuro, J; Kikuchi, T; Suzuki, M; Takatsuki, F1
ElAttar, TM; Virji, AS1
Half, E; Kuo, MT; Sinicrope, FA; Sun, Y; Tang, XM1
Evans, JF; Kargman, S; Kelly, CR; Kwong, E; Lam, EC; Luk, P; Wolfe, MM; Yao, M; Zheng, Y1
Cai, SH; Li, XH; Li, XK; Ren, XD; Tang, FX; Zhong, XY1
Hashitani, S; Maeda, T; Nishimura, N; Noguchi, K; Sakurai, K; Takaoka, K; Urade, M1
Breza, TS; Oberyszyn, TM; Tober, KL; Wilgus, TA1
Gouveris, P; Katsoulas, HL; Kosmas, C; Kosmas, N; Papalambros, E; Papantoniou, N; Rokana, S; Skopeliti, M; Tsavaris, NB; Tsitsilonis, OE1
Albert, A; Chang, AJ; Liu, TC; Sangha, S; Wolfe, MM; Yao, M; Zhou, W1
Kotani, T; Murashima, Y; Nakagiri, A; Takeuchi, K1
Adleff, V; Budai, B; Jeney, A; Kralovánszky, J; Pap, E; Réti, A1
Brazowski, E; Eisenthal, A; Eytan, K; Gitstein, G; Greenberg, R; Skornick, Y1
Hatano, H; Higashikawa, K; Kamata, N; Okui, G; Ono, S; Rizqiawan, A; Shigeishi, H; Tanaka, F; Tobiume, K; Tran, TT1
Cai, H; Cao, G; Chang, W; Ding, Y; Fu, C; Han, Y; Liu, Y; Ma, L; Su, T; Tan, X; Yu, Y; Zhang, H1
Guo, QL; Lu, ZJ; Sha, YY; Yao, J; You, QD; Zhao, L; Zhao, Q; Zhu, BB1
Bellamkonda, K; Sime, W; Sjölander, A1
Das, UN; Ni, X; Shen, S; Yu, H; Zhang, C1
Nakamura, K; Sasayama, A; Takahashi, T; Yamaji, T1
An, N; Chen, D; Fan, J; Li, J; Liu, C; Luo, J; Su, W; Wang, H; Zhao, J; Zhou, Y1
Assem, NZ; Duque, C; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Louzada, LM; Theodoro, LH1
Cai, X; Chen, H; Cheng, J; Fan, Y; Fu, A; Huang, Y; Li, H; Li, M; Long, F; Nie, C; Shao, L; Yue, M; Zeng, H; Zhang, X; Zhu, Q1
Ma, H; Mao, R; Tang, Y; Yan, H; Zhang, Y; Zhao, Y1
Cao, L; Geng, L; Geng, S; Ren, X; Zhan, H1
Ao, H; Liu, D; Peng, C; Tang, F; Xu, LY; Zhang, JN; Zhang, L; Zhao, XL1

Other Studies

30 other study(ies) available for fluorouracil and dinoprostone

ArticleYear
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:5

    Topics: Allopurinol; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Oocytes; Organic Anion Transporters, Sodium-Independent; Substrate Specificity; Xenopus laevis

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Studies of eicosanoid production in the air pouch model of synovial inflammation.
    Agents and actions, 1986, Volume: 18, Issue:3-4

    Topics: 6-Ketoprostaglandin F1 alpha; Air; Animals; Carrageenan; Colchicine; Dinoprostone; Disease Models, Animal; Female; Fluorouracil; Inflammation; Kinetics; L-Lactate Dehydrogenase; Neutrophils; Pertussis Vaccine; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Synovial Fluid

1986
The effect of prostaglandins E1 and E2 on macrophage progenitor cells with high proliferative potential in mouse bone marrow in vitro.
    Blood, 1984, Volume: 63, Issue:6

    Topics: Alprostadil; Animals; Bone Marrow Cells; Cell Division; Dinoprostone; Fluorouracil; Humans; Macrophages; Male; Mice; Mice, Inbred BALB C; Prostaglandins E; Stem Cells

1984
Effects of prostaglandin E2 on the micronucleus formation in mouse bone marrow cells by various mutagens.
    Mutation research, 1994, Dec-01, Volume: 311, Issue:2

    Topics: 2-Naphthylamine; Animals; Benzo(a)pyrene; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Dimethylhydrazines; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Erythroblasts; Erythropoiesis; Erythropoietin; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Micronucleus Tests; Mitomycin; Mutagens; Time Factors; Vincristine

1994
Cancer cell progression and chemoimmunotherapy--dual effects in the induction of resistance to therapy.
    British journal of cancer, 1996, Volume: 73, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Avian Sarcoma Viruses; Combined Modality Therapy; Cyclophosphamide; Dinoprostone; Disease Progression; Drug Resistance, Neoplasm; Female; Fibrosarcoma; Fluorouracil; Immunotherapy; Interleukin-2; Lentinan; Mice; Mice, Inbred Strains; Transforming Growth Factor beta

1996
Inhibition of growth in oral squamous carcinoma cells by cyclopentenone prostaglandins: comparison with chemotherapeutic agents.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:6

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Dinoprostone; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Prostaglandin D2; Prostaglandins A; Prostaglandins A, Synthetic; Prostaglandins, Synthetic; Tocopherols; Tumor Cells, Cultured; Vitamin E

1997
Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells.
    Cancer research, 2002, Nov-01, Volume: 62, Issue:21

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase Inhibitors; Caspases; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome c Group; Dinoprostone; Enzyme Activation; Fluorouracil; Humans; Isoenzymes; Membrane Proteins; Mitochondria; Nitrobenzenes; Nucleic Acid Synthesis Inhibitors; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Sulfonamides; Transfection; Tumor Cells, Cultured

2002
Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice.
    Cancer research, 2003, Feb-01, Volume: 63, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; beta Catenin; Camptothecin; Cell Division; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytoskeletal Proteins; Dinoprostone; Drug Synergism; Endothelial Growth Factors; Fluorouracil; Intercellular Signaling Peptides and Proteins; Interleukin-10; Interleukin-12; Irinotecan; Isoenzymes; Lactones; Liver Neoplasms, Experimental; Lymphokines; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Sulfones; Trans-Activators; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Synergistic effects of nimesulide and 5-fluorouracil on tumor growth and apoptosis in the implanted hepatoma in mice.
    World journal of gastroenterology, 2003, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Apoptosis; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Fluorouracil; Liver Neoplasms, Experimental; Mice; Microscopy, Electron; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Sulfonamides; Tumor Suppressor Protein p53

2003
Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines.
    International journal of oncology, 2003, Volume: 23, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Bleomycin; Blotting, Western; Carcinoma; Celecoxib; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulindac; Time Factors; Vincristine

2003
Treatment with 5-fluorouracil and celecoxib displays synergistic regression of ultraviolet light B-induced skin tumors.
    The Journal of investigative dermatology, 2004, Volume: 122, Issue:6

    Topics: Administration, Topical; Animals; Antimetabolites, Antineoplastic; Celecoxib; Cell Division; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Mice; Mice, Hairless; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Ultraviolet Rays

2004
The effect of Edrecolomab (Mo17-1A) or fluorouracil-based chemotherapy on specific immune parameters in patients with colorectal cancer. A comparative study.
    Oncology, 2004, Volume: 67, Issue:5-6

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colectomy; Colorectal Neoplasms; Cytokines; Dinoprostone; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukins; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasm Staging; Tumor Necrosis Factor-alpha

2004
Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Feb-15, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Fluorouracil; HT29 Cells; Humans; Ibuprofen; Irinotecan; Lactones; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Sulfones; Survival Analysis; Xenograft Model Antitumor Assays

2005
Prophylactic effect of lafutidine against the adverse reaction induced in rat stomach by repeated administration of 5-fluorouracil.
    Inflammopharmacology, 2007, Volume: 15, Issue:5

    Topics: Acetamides; Animals; Anti-Ulcer Agents; Cimetidine; Dinoprostone; Drug Interactions; Fluorouracil; Gastric Mucosa; Hydrochloric Acid; Male; Membrane Potentials; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach; Stomach Ulcer; Taurocholic Acid

2007
Enhanced 5-fluorouracil cytotoxicity in high cyclooxygenase-2 expressing colorectal cancer cells and xenografts induced by non-steroidal anti-inflammatory drugs via downregulation of dihydropyrimidine dehydrogenase.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Collagen; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dihydrouracil Dehydrogenase (NADP); Dinoprostone; Down-Regulation; Drug Interactions; Extracellular Matrix; Fluorescent Antibody Technique; Fluorouracil; HT29 Cells; Humans; Indomethacin; Nitrobenzenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Xenograft Model Antitumor Assays

2010
Effects of 5-FU on DNA synthesis and cytotoxicity of human lymphocytes induced by IL-2, TGF-beta3 and PGE2.
    Anticancer research, 2009, Volume: 29, Issue:10

    Topics: Cell Cycle; Cells, Cultured; Culture Media; Cytotoxicity, Immunologic; Dinoprostone; DNA; Drug Interactions; Fluorouracil; Humans; Interleukin-2; Lymphocyte Activation; Lymphocytes; Receptors, Interleukin-2; Thymidine; Transforming Growth Factor beta3

2009
PGE₂ targets squamous cell carcinoma cell with the activated epidermal growth factor receptor family for survival against 5-fluorouracil through NR4A2 induction.
    Cancer letters, 2011, Aug-28, Volume: 307, Issue:2

    Topics: Antineoplastic Agents; Base Sequence; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Dinoprostone; DNA Primers; ErbB Receptors; Fluorouracil; Humans; Nuclear Receptor Subfamily 4, Group A, Member 2; Reverse Transcriptase Polymerase Chain Reaction

2011
Nuclear orphan receptor NR4A2 confers chemoresistance and predicts unfavorable prognosis of colorectal carcinoma patients who received postoperative chemotherapy.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:16

    Topics: Adenoma; Adenomatous Polyposis Coli; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Chemotherapy, Adjuvant; Chi-Square Distribution; Colorectal Neoplasms; Dinoprostone; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluorouracil; HCT116 Cells; Humans; Intestinal Polyps; Kaplan-Meier Estimate; Leucovorin; Multivariate Analysis; Neoplasm Staging; Nuclear Receptor Subfamily 4, Group A, Member 2; Organoplatinum Compounds; Proportional Hazards Models; Time Factors; Transfection; Treatment Outcome; Up-Regulation

2013
Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2013, Volume: 91, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Female; Flavanones; Fluorouracil; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction

2013
The impact of inflammatory lipid mediators on colon cancer-initiating cells.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:11

    Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Dinoprostone; Disease Progression; Drug Resistance, Neoplasm; Female; Fluorouracil; HCT116 Cells; HT29 Cells; Humans; Inflammation; Leukotriene D4; Lipids; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Tumor Microenvironment; Xenograft Model Antitumor Assays

2015
Growth inhibitory effect of polyunsaturated fatty acids (PUFAs) on colon cancer cells via their growth inhibitory metabolites and fatty acid composition changes.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Antimetabolites, Antineoplastic; Arachidonate 5-Lipoxygenase; Cell Line, Tumor; Colorectal Neoplasms; Cyclooxygenase 2; Dinoprostone; Fatty Acids; Fatty Acids, Unsaturated; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Intramolecular Oxidoreductases; Leukotriene B4; Lipocalins; Lipoxins; Prostaglandin-E Synthases

2015
An Immune-Modulating Diet in Combination with Chemotherapy Prevents Cancer Cachexia by Attenuating Systemic Inflammation in Colon 26 Tumor-Bearing Mice.
    Nutrition and cancer, 2015, Volume: 67, Issue:6

    Topics: Animals; Antineoplastic Agents; Blood Glucose; Cachexia; Cell Line, Tumor; Colon; Colonic Neoplasms; Diet; Dinoprostone; Disease Models, Animal; Energy Intake; Fluorouracil; Immunologic Factors; Immunosuppressive Agents; Inflammation; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Organ Size; Vascular Endothelial Growth Factor A

2015
Oxytocin evokes a pulsatile PGE2 release from ileum mucosa and is required for repair of intestinal epithelium after injury.
    Scientific reports, 2015, Jul-10, Volume: 5

    Topics: Animals; Antineoplastic Agents; Calcium; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Evoked Potentials; Fluorouracil; Ileum; Immunohistochemistry; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Ions; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Neoplasms; Oxytocin; Rats; Rats, Wistar; Receptors, Oxytocin; Wound Healing; Xanthones

2015
Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy.
    Journal of periodontal research, 2016, Volume: 51, Issue:5

    Topics: Alveolar Bone Loss; Animals; Bacteria; Caspase 3; Combined Modality Therapy; Dental Scaling; Dinoprostone; Drug Therapy; Fluorouracil; Inflammation; Interleukin-6; Low-Level Light Therapy; Male; Mandible; Molar; Osteoprotegerin; Periodontitis; RANK Ligand; Rats; Rats, Wistar; Root Planing; Tumor Necrosis Factor-alpha

2016
Prostaglandin E2 accelerated recovery of chemotherapy-induced intestinal damage by increasing expression of cyclin D.
    Experimental cell research, 2020, 03-15, Volume: 388, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Proliferation; Cyclin D; Dinoprostone; Fluorouracil; Gene Expression Regulation; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Oxytocics; Stem Cells; Tumor Cells, Cultured

2020
Sprayable NAHAO® hydrogel alleviates pain and accelerates rat oral mucositis wound healing.
    Journal of stomatology, oral and maxillofacial surgery, 2023, Volume: 124, Issue:1S

    Topics: Animals; Capsaicin; Cyclooxygenase 2; Dinoprostone; Fluorouracil; Humans; Hydrogels; Male; Matrix Metalloproteinase 9; Pain; Rats; Rats, Sprague-Dawley; Stomatitis; Wound Healing

2023
Targeting PTGES/PGE2 axis enhances sensitivity of colorectal cancer cells to 5-fluorouracil.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2023, Dec-01, Volume: 101, Issue:6

    Topics: Cell Line, Tumor; Colorectal Neoplasms; Dinoprostone; Drug Resistance, Neoplasm; Fluorouracil; Humans; Prostaglandin-E Synthases

2023
    Journal of agricultural and food chemistry, 2023, Oct-18, Volume: 71, Issue:41

    Topics: Alpinia; Animals; Diarrhea; Dinoprostone; Fluorouracil; Gastrointestinal Microbiome; Mice; Mucositis; Oils, Volatile; Prostaglandin-E Synthases

2023
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