Page last updated: 2024-08-22

fluorine and uracil

fluorine has been researched along with uracil in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199024 (64.86)18.7374
1990's1 (2.70)18.2507
2000's9 (24.32)29.6817
2010's3 (8.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cech, D; Herrmann, G; Holy, A1
Cech, D; Hein, L; Langen, P; Otto, A; von Janta-Lipinski, M; Wuttke, R1
Cech, D; Etzold, G; Wohlfeil, R1
An, SH; Bernacki, RJ; Bobek, M; De Clercq, E; Skrincosky, D1
Chou, TY; David, M; Giese, RW; Saha, M; Vouros, P1
Pitot, HC; Wilkinson, DS1
Arnason, BG; Chelmicka-Szorc, E; Darzynkiewicz, Z1
Kobayashi, GS; Kwan, CN; Medoff, G; Schlessinger, D; Venkov, P1
Slouka, J; Stránský, Z1
Abola, EE; Deutsch, HF; Edmundson, AB; Ely, KR; Fausch, MD; Girling, RL; Schiffer, M; Westholm, FA1
Fenster, ED1
Laland, SG; Oyen, TB1
Barton, DH; Hesse, RH; Pechet, MM; To, HT1
Baranosky, J; Lebowitz, E; Richards, P1
Hollander, VP; Mashburn, LT; Stevens, J; Stevens, YW1
Sakai, TT; Santi, DV1
Semonský, M1
Rogers, WI; Wilson, JA1
Jund, R; Lacroute, F1
Giege, R; Weil, JH1
Goodman, L; Lee, WW; Martinez, AP1
Bieber, AL; Mott, DM1
Bunker, JE; Keller, F; Tyrrill, AR1
Kanazawa, Y; Kurogi, S; Masuda, K; Noda, Y; Shinohara, S1
BOOHAR, J; HEIDELBERGER, C; KAMPSCHROER, B1
Cao, C; Jiang, YL; McDowell, LM; Poliks, B; Potter, GS; Schaefer, J; Song, F; Stivers, JT; Studelska, DR1
Antonakis, K; Dorange, I; Egron, MJ; Herscovici, J; Komiotis, D; Ollapally, AP1
Campos, JM; Díaz-Gavilán, M; Entrena, A; Espinosa, A; Gallo, MA; Gómez-Vidal, JA1
Aceña, JL; Catalan, S; Fernandez, B; Fustero, S; Piera, J; Sanz-Cervera, JF1
Eaton, BE; Gaballah, ST; Netzel, TL; Vaught, JD1
Barone, V; Gustavsson, T; Improta, R; Santoro, F1
Nowak, I; Robins, MJ1
Barchi, JJ; George, C; Karki, RG; Marquez, VE; Mikhailopulo, IA; Nicklaus, MC; Siddiqui, MA1
La Colla, P; Loddo, R; Loksha, YM; Pedersen, EB1
Hu, J; Ju, Y; Lu, J; Song, Y1
Ellipilli, S; Ganesh, KN; Palvai, S1
He, CY; Kong, J; Li, X; Yao, Q; Yuan, FM1

Other Studies

37 other study(ies) available for fluorine and uracil

ArticleYear
Fluorination of 6-methyluracil and its nlcleosides.
    Nucleic acids research, 1977, Volume: 4, Issue:9

    Topics: Chemical Phenomena; Chemistry; Fluorine; Mass Spectrometry; Methods; Spectrophotometry, Ultraviolet; Uracil; Uridine

1977
Synthesis of substituted 5-fluoro-5,6-dihydropyrimidines.
    Nucleic acids research, 1975, Volume: 2, Issue:11

    Topics: Fluorine; Mass Spectrometry; Methods; Pyrimidinones; Thymine; Uracil

1975
A facile synthesis of 5-(perfluoroalkyl)-pyrimidines.
    Nucleic acids research, 1975, Volume: 2, Issue:11

    Topics: Deoxyuridine; Fluorine; Methods; Pyrimidinones; Uracil; Uridine

1975
2'-Fluorinated isonucleosides. 1. Synthesis and biological activity of some methyl 2'-deoxy-2'-fluoro-2'-pyrimidinyl-D-arabinopyranosides.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Animals; Arabinonucleosides; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Female; Fluorine; Humans; Kinetics; Leukemia L1210; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Conformation; Neoplasms, Experimental; Nucleotides; Sarcoma, Experimental; Tumor Cells, Cultured; Uracil; Viruses

1989
Replacement of aromatic fluorine by a methoxy group during reaction with methyl iodide in N,N-dimethylformamide solvent.
    Biomedical & environmental mass spectrometry, 1987, Volume: 14, Issue:1

    Topics: Acylation; Dimethylformamide; Fluorine; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Iodinated; Methylation; Protons; Solvents; Uracil

1987
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
    The Journal of biological chemistry, 1973, Jan-10, Volume: 248, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Tritium; Uracil; Uridine

1973
Chick-erythrocyte nucleus reactivation in heterokaryons: suppression by inhibitors of proteolytic enzymes.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:3

    Topics: Animals; Arginine; Cell Nucleus; Chickens; Chlorine; Depression, Chemical; DNA; Erythrocytes; Female; Fluorine; HeLa Cells; Humans; Hybrid Cells; Kinetics; Lysine; Phenylalanine; Protease Inhibitors; RNA; Sulfones; Thymidine; Thymine; Tosyl Compounds; Tritium; Uracil; Uridine

1974
Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism).
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:1

    Topics: Acrylamides; Amphotericin B; Antifungal Agents; Candida; Candida albicans; Carbon Isotopes; Cell Membrane Permeability; Cryptococcus neoformans; Cytosine; Drug Combinations; Drug Synergism; Electrophoresis; Fluorine; Microbial Sensitivity Tests; Rifampin; RNA; Saccharomyces cerevisiae; Tritium; Uracil

1972
[1-Aryl-6-azauracils. 15. Synthesis of some 2,4-dinitrophenyl derivatives].
    Die Pharmazie, 1973, Volume: 28, Issue:5

    Topics: Benzyl Compounds; Chemical Phenomena; Chemistry; Dinitrophenols; Fluorine; Hydrolysis; Nitrogen; Uracil

1973
Binding of 2,4-dinitrophenyl compounds and other small molecules to a crystalline lambda-type Bence-Jones dimer.
    Biochemistry, 1974, Aug-27, Volume: 13, Issue:18

    Topics: Amino Acid Sequence; Amino Acids; Amyloidosis; Bence Jones Protein; Binding Sites; Caffeine; Chemical Phenomena; Chemistry; Colchicine; Dansyl Compounds; Fluorine; Humans; Immunoglobulin Fragments; Immunoglobulins; Iodine; Macromolecular Substances; Methadone; Models, Structural; Morphine; Nitrobenzenes; Phenanthrolines; Protein Binding; Protein Conformation; Uracil; Vitamin K; X-Ray Diffraction

1974
Nucleic acid and ribosome synthesis by Escherichia coli incubated in 5',5',5'-trifluoroleucine.
    Biochimica et biophysica acta, 1971, Feb-11, Volume: 228, Issue:3

    Topics: Adaptation, Physiological; Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Culture Media; Depression, Chemical; Dialysis; DNA, Bacterial; Escherichia coli; Fluorine; Glucose; Leucine; Mutation; Ribosomes; RNA, Bacterial; Stimulation, Chemical; Tritium; Uracil

1971
5-fluoropyrimidin-2-one deoxyriboside and its growth-inhibiting properties.
    Biochimica et biophysica acta, 1969, Jun-17, Volume: 182, Issue:2

    Topics: Carbon Isotopes; DNA Replication; Escherichia coli; Fluorine; Kinetics; Lactobacillus acidophilus; Nucleosides; Pyrimidinones; RNA; Spectrum Analysis; Transferases; Ultraviolet Rays; Uracil

1969
A convenient synthesis of 5-fluorouracil.
    The Journal of organic chemistry, 1972, Jan-28, Volume: 37, Issue:2

    Topics: Fluorine; Fluorouracil; Methods; Uracil

1972
18 F recoil labeling.
    The International journal of applied radiation and isotopes, 1972, Volume: 23, Issue:8

    Topics: Deuterium; Fluorine; Fluorouracil; Isotope Labeling; Methods; Neon; Radioisotopes; Radionuclide Imaging; Uracil

1972
Glucocorticoid inhibition of precursor incorporation into nuclear RNA of P1798 lymphosarcoma.
    Biochimica et biophysica acta, 1971, Mar-11, Volume: 232, Issue:2

    Topics: Animals; Carbon Isotopes; Cell Biology; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; Depression, Chemical; Fluorine; Hydrogen-Ion Concentration; In Vitro Techniques; Lymphoma, Non-Hodgkin; Mice; Mitochondria; Nucleosides; Nucleotides; Orotic Acid; Prednisolone; Pyrimidines; RNA, Neoplasm; RNA, Ribosomal; Solubility; Time Factors; Tritium; Uracil; Uridine

1971
Thymidylate synthetase. Model studies of inhibition by 5-trifluoromethyl-2'-deoxyuridylic acid.
    Biochemistry, 1971, Sep-14, Volume: 10, Issue:19

    Topics: Acylation; Alkylation; Amines; Azides; Carboxylic Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Deoxyribonucleotides; Fluorine; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Methylation; Methyltransferases; Models, Chemical; Spectrophotometry; Uracil; Uracil Nucleotides

1971
New cancerostatics developed in Czechoslovakia. Introductory lecture.
    Neoplasma, 1971, Volume: 18, Issue:5

    Topics: Acrylates; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Benzoates; Bromine; Cytidine; Fluorine; Humans; Hypoxanthines; Nitrogen Mustard Compounds; Pyrimidines; Thiazines; Uracil; Valerates

1971
Determination of labile trifluoromethyl compounds with a fluoride--ion electrode: differential analysis of 5-trifluoromethyluracil and 5-trifluoromethyl-2'-deoxyuridine.
    Analytical biochemistry, 1969, Oct-15, Volume: 32, Issue:1

    Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Electrodes; Fluorides; Fluorine; Humans; Hydrogen-Ion Concentration; Methods; Neoplasms; Uracil; Uridine

1969
Genetic and physiological aspects of resistance to 5-fluoropyrimidines in Saccharomyces cerevisiae.
    Journal of bacteriology, 1970, Volume: 102, Issue:3

    Topics: Aminohydrolases; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Chromatography, Thin Layer; Chromosome Mapping; Cytosine; Drug Resistance, Microbial; Fluorine; Fluorouracil; Genetics, Microbial; Membrane Transport Proteins; Mutation; Phosphorus Isotopes; Phosphotransferases; Saccharomyces; Spectrophotometry; Transferases; Uracil; Uridine

1970
[tRNA's from yeast having incorporated 5-fluorouracil arising from in vivo deamination of 5-fluorocytosine].
    Bulletin de la Societe de chimie biologique, 1970, Mar-31, Volume: 52, Issue:2

    Topics: Adenine; Amino Acids; Aminohydrolases; Chromatography, Paper; Cytosine; Deamination; Fluorine; Fluorouracil; Guanine; Mutation; RNA, Transfer; Saccharomyces; Spectrophotometry; Ultraviolet Rays; Uracil

1970
2-Fluoroethylamines. 3. Some alkylating agents derived from uracil.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:2

    Topics: Alkylating Agents; Chemical Phenomena; Chemistry, Physical; Chromatography, Paper; Ethylamines; Fluorine; Uracil; Uracil Mustard

1968
Nucleotide activation of phosphorylase b in the presence and absence of salmine.
    Biochemical and biophysical research communications, 1968, Feb-26, Volume: 30, Issue:4

    Topics: Acetates; Adenine Nucleotides; Amides; Animals; Azaguanine; Binding Sites; Chlorine; Cytosine Nucleotides; Fluorine; Glucosyltransferases; Guanine Nucleotides; Kinetics; Mercaptopurine; Muscles; Nucleosides; Nucleotides; Protamines; Rabbits; Uracil; Uracil Nucleotides; Xanthines

1968
A direct synthesis of 1-beta-D-arabinofuranosyl-5-fluorocytosine.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Arabinose; Cytosine; Fluorine; Fluorouracil; Nucleosides; Pyrimidines; Thiouracil; Uracil

1967
In vivo 19F NMR comparative study of 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil (FT) and an FT-uracil coadministration system in mouse tumors.
    Chemical & pharmaceutical bulletin, 1994, Volume: 42, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorine; Fluorouracil; Liver; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Sarcoma 180; Tegafur; Uracil

1994
FLUORINATED PYRIMIDINES. XXIV. IN VIVO METABOLISM OF 5-TRIFLUOROMETHYLURACIL-2-C-14 AND 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE-2-C-14.
    Cancer research, 1965, Volume: 25

    Topics: Animals; Carbon Isotopes; Deoxyuridine; DNA; Fluorine; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Pyrimidines; Radiometry; Research; Trifluridine; Uracil

1965
Recognition of an unnatural difluorophenyl nucleotide by uracil DNA glycosylase.
    Biochemistry, 2004, Dec-14, Volume: 43, Issue:49

    Topics: Amino Acid Substitution; Binding Sites; Catalysis; DNA Glycosylases; Enzyme Stability; Escherichia coli Proteins; Floxuridine; Fluorine; Hydrogen Bonding; Leucine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Heteroduplexes; Solutions; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics; Uracil; Uracil-DNA Glycosidase

2004
New short route to unsaturated fluoroketonucleosides: case of 5-fluoro-1-(6-O-acetyl-3,4-di-deoxy-3-fluoro-beta-D-glycero-hex-3-eno-pyranos-2-ulosyl) uracil.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:4

    Topics: Chromatography, Thin Layer; Fluorine; Fluorouracil; Immunosuppressive Agents; Ketones; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleosides; Uracil

2005
Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom.
    The Journal of organic chemistry, 2006, Feb-03, Volume: 71, Issue:3

    Topics: Acetals; Electrons; Fluorine; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen; Pyrimidines; Uracil

2006
Synthesis and biological evaluation of new bicyclic fluorinated uracils through ring-closing metathesis.
    The Journal of organic chemistry, 2006, May-12, Volume: 71, Issue:10

    Topics: Fluorine; Molecular Structure; Uracil

2006
Charge-transfer excited state dynamics in DNA hairpins substituted with an ethylenylpyrenyl-dU electron source and halo-dU traps.
    The journal of physical chemistry. B, 2005, Mar-31, Volume: 109, Issue:12

    Topics: Bromine; Circular Dichroism; DNA; Electrons; Fluorine; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Pyrenes; Uracil

2005
Solvent effect on the singlet excited-state lifetimes of nucleic acid bases: A computational study of 5-fluorouracil and uracil in acetonitrile and water.
    Journal of the American Chemical Society, 2006, Dec-20, Volume: 128, Issue:50

    Topics: Absorption; Acetonitriles; Computer Simulation; Fluorine; Models, Molecular; Molecular Conformation; Nucleic Acids; Solvents; Time Factors; Uracil; Water

2006
Trifluoromethylation of alkenyl bromides and iodides (including 5-iodouracils) with (CF3)2Hg and Cu ("trifluoromethylcopper").
    The Journal of organic chemistry, 2007, Mar-30, Volume: 72, Issue:7

    Topics: Alkenes; Bromides; Fluorine; Iodides; Methylation; Molecular Structure; Organometallic Compounds; Uracil

2007
Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid state.
    Journal of the American Chemical Society, 2008, Jul-16, Volume: 130, Issue:28

    Topics: Crystallography, X-Ray; Deoxyuridine; Fluorine; Fourier Analysis; Hydrocarbons, Fluorinated; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrimidine Nucleosides; Uracil; Uridine

2008
Synthesis and anti-HIV-1 activity of 1-substiuted 6-(3-cyanobenzoyl) and [(3-cyanophenyl)fluoromethyl]-5-ethyl-uracils.
    Archiv der Pharmazie, 2009, Volume: 342, Issue:9

    Topics: Anti-HIV Agents; Cell Line; Cell Survival; Diethylamines; Drug Evaluation, Preclinical; Drug Resistance, Viral; Fluorine; HIV Reverse Transcriptase; HIV-1; Molecular Structure; Mutation; Reverse Transcriptase Inhibitors; Uracil

2009
A new dual-responsive organogel based on uracil-appended glycyrrhetinic acid.
    Organic letters, 2011, Jul-01, Volume: 13, Issue:13

    Topics: Fluorine; Gels; Glycyrrhetinic Acid; Mercury; Microscopy, Electron, Scanning; Molecular Structure; Uracil

2011
Fluorinated Peptide Nucleic Acids with Fluoroacetyl Side Chain Bearing 5-(F/CF3)-Uracil: Synthesis and Cell Uptake Studies.
    The Journal of organic chemistry, 2016, 08-05, Volume: 81, Issue:15

    Topics: Animals; Chromatography, High Pressure Liquid; DNA, Complementary; Flow Cytometry; Fluorides; Fluorine; Halogenation; HeLa Cells; Humans; Hydrogen Bonding; Mice; NIH 3T3 Cells; Peptide Nucleic Acids; RNA; Solubility; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Ultraviolet Rays; Uracil

2016
Visible-Light-Induced Direct Difluoroalkylation of Uracils, Pyridinones, and Coumarins.
    The Journal of organic chemistry, 2017, 01-20, Volume: 82, Issue:2

    Topics: Alkylation; Coumarins; Fluorine; Light; Molecular Structure; Pyridones; Uracil

2017