Page last updated: 2024-09-03

fk 633 and tirofiban

fk 633 has been researched along with tirofiban in 3 studies

Compound Research Comparison

Studies
(fk 633)
Trials
(fk 633)
Recent Studies (post-2010)
(fk 633)
Studies
(tirofiban)
Trials
(tirofiban)
Recent Studies (post-2010) (tirofiban)
19011,210309427

Protein Interaction Comparison

ProteinTaxonomyfk 633 (IC50)tirofiban (IC50)
Integrin subunit alpha 2bRattus norvegicus (Norway rat)0.13
Integrin beta-3Homo sapiens (human)0.1184
Integrin alpha-V Homo sapiens (human)0.011
Integrin alpha-IIbHomo sapiens (human)0.1225
Integrin beta-3 Rattus norvegicus (Norway rat)0.13

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gretler, DD; Scarborough, RM1
Aoki, T; Honda, S; Okubo, M; Seki, J; Senzaki, K; Takahashi, F; Takasugi, H; Tanaka, A; Tomiyama, Y1
Aoki, T; Honda, S; Kurata, Y; Matsuzawa, Y; Seki, J; Shiraga, M; Tomiyama, Y1

Reviews

1 review(s) available for fk 633 and tirofiban

ArticleYear
Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents.
    Journal of medicinal chemistry, 2000, Sep-21, Volume: 43, Issue:19

    Topics: Administration, Oral; Animals; Antibodies, Monoclonal; Clinical Trials as Topic; Drug Design; Fibrinolytic Agents; Humans; Injections; Integrins; Molecular Mimicry; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Snake Venoms

2000

Other Studies

2 other study(ies) available for fk 633 and tirofiban

ArticleYear
Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis.
    Thrombosis and haemostasis, 1998, Volume: 79, Issue:6

    Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Apyrase; Aspirin; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Dipeptides; Fibrinogen; Humans; Ion Transport; Peptide Fragments; Phenylacetates; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Thromboxane A2; Thromboxane B2; Tirofiban; Tyrosine

1998
Association between ligand-induced conformational changes of integrin IIbbeta3 and IIbbeta3-mediated intracellular Ca2+ signaling.
    Blood, 1998, Nov-15, Volume: 92, Issue:10

    Topics: Acetates; Antibodies, Monoclonal; Benzamidines; Calcium Signaling; Dipeptides; Humans; Intracellular Fluid; Molecular Structure; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Structure-Activity Relationship; Tirofiban; Tyrosine; Valerates

1998