fingolimod and sew2871
fingolimod has been researched along with sew2871 in 3 studies
Compound Research Comparison
| Studies (fingolimod) | Trials (fingolimod) | Recent Studies (post-2010) (fingolimod) | Studies (sew2871) | Trials (sew2871) | Recent Studies (post-2010) (sew2871) |
|---|---|---|---|---|---|
| 65 | 0 | 51 | 95 | 0 | 57 |
Protein Interaction Comparison
| Protein | Taxonomy | fingolimod (IC50) | sew2871 (IC50) |
|---|---|---|---|
| Sphingosine 1-phosphate receptor 1 | Homo sapiens (human) | 0.037 | |
| Sphingosine 1-phosphate receptor 5 | Homo sapiens (human) | 4.6 |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bergstrom, J; Card, D; Chrebet, G; Ferrer, M; Hajdu, R; Hale, JJ; Hodder, P; Keohane, CA; Lynch, CL; Mandala, S; Milligan, JA; Mills, SG; Neway, W; Parent, SA; Rosen, H; Rosenbach, MJ; Shei, GJ; Strulovici, B | 1 |
| Arnett, HA; Cee, VJ; Croghan, MD; Fiorino, M; Fotsch, C; Frohn, MJ; Harrington, PE; Horner, M; Lanman, BA; Lee, MR; McElvain, M; Morrison, HG; Pennington, LD; Pickrell, AJ; Reed, AB; Sham, KK; Tasker, AS; Wong, M; Xu, H; Xu, Y; Zhang, X | 1 |
| Camp, SM; Garcia, JGN; Marciniak, A; Polt, R | 1 |
Reviews
1 review(s) available for fingolimod and sew2871
| Article | Year |
|---|---|
An update on sphingosine-1-phosphate receptor 1 modulators.
Topics: Autoimmune Diseases; Biological Availability; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Oxadiazoles; Receptors, Lysosphingolipid; Sphingolipids | 2018 |
Other Studies
2 other study(ies) available for fingolimod and sew2871
| Article | Year |
|---|---|
A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.
Topics: Administration, Oral; Animals; Azetidines; Biological Availability; CHO Cells; Cricetinae; Dogs; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunosuppressive Agents; Lymphocytes; Macaca mulatta; Mice; Rats; Rats, Inbred Lew; Receptors, Lysosphingolipid; Structure-Activity Relationship | 2004 |
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity.
Topics: Animals; Area Under Curve; Cardiovascular Diseases; Chemistry, Physical; Drug Design; Female; Humans; Immunosuppressive Agents; In Vitro Techniques; Kinetics; Lymphocytes; Models, Chemical; Multiple Sclerosis; Quinolones; Rats; Rats, Inbred Lew; Receptors, Lysosphingolipid; Structure-Activity Relationship | 2012 |