felbamate and glycine

felbamate has been researched along with glycine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (72.22)18.2507
2000's2 (11.11)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E1
Nolan, JP; Panizzon, KL; Wallis, RA2
McQuade, RD; Taylor, LA; Tice, MA1
Harmsworth, WL; Sofia, RD; White, HS; Wolf, HH1
Ary, T; Faull, RL; McCabe, RT; Narang, N; Sofia, RD; Wamsley, JK1
Ary, T; Faull, RL; Gan, XD; McCabe, RT; Narang, N; Sofia, RD; Wamsley, JK1
Barnett, A; Coffin, V; Cohen-Williams, M1
Panizzon, KL; Wallis, RA1
Adams, LM; Sofia, RD; Wasterlain, CG; Wichmann, JK1
Gunasekar, PG; Kanthasamy, AG; Matsumoto, RR; Trunong, DD1
Faull, RL; Layer, RT; Leiner, KA; McCabe, RT; Narang, N; Sofia, RD; Wamsley, JK1
Chen, CC; Glazewski, JC; Kleckner, NW; Moscrip, TD1
Mazarati, AM; Rogawski, MA; Wasterlain, CG1
Chang, HR; Kuo, CC1

Other Studies

18 other study(ies) available for felbamate and glycine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission

1994
Glycine-induced CA1 excitotoxicity in the rat hippocampal slice.
    Brain research, 1995, Jul-10, Volume: 685, Issue:1-2

    Topics: Animals; Anticonvulsants; Evoked Potentials; Felbamate; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Pyramidal Cells; Rats; Rats, Sprague-Dawley

1995
Felbamate, a novel antiepileptic drug, reverses N-methyl-D-aspartate/glycine-stimulated increases in intracellular Ca2+ concentration.
    European journal of pharmacology, 1995, Apr-28, Volume: 289, Issue:2

    Topics: Animals; Anticonvulsants; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Felbamate; Glycine; Hippocampus; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors

1995
Felbamate modulates the strychnine-insensitive glycine receptor.
    Epilepsy research, 1995, Volume: 20, Issue:1

    Topics: Animals; Anticonvulsants; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Felbamate; Glycine; Mice; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Receptors, Glycine; Serine; Strychnine

1995
Glycine-induced CA1 excitotoxicity in the rat hippocampal slice.
    Brain research, 1994, Nov-21, Volume: 664, Issue:1-2

    Topics: Animals; Anticonvulsants; Chlorides; Drug Synergism; Evoked Potentials; Felbamate; Glycine; Hippocampus; Histidine; In Vitro Techniques; Kynurenic Acid; Magnesium Sulfate; Male; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Zinc Compounds

1994
Interaction of felbamate with [3H]DCKA-labeled strychnine-insensitive glycine receptors in human postmortem brain.
    Experimental neurology, 1994, Volume: 129, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Autopsy; Autoradiography; Binding, Competitive; Brain; Felbamate; Female; Glycine; Hippocampus; Humans; Kinetics; Kynurenic Acid; Male; Mesencephalon; Middle Aged; Neurons; Organ Specificity; Phenylcarbamates; Propylene Glycols; Radioligand Assay; Receptors, Glycine; Strychnine; Tritium

1994
Felbamate: interaction with glycine receptors in human cerebral cortex.
    Proceedings of the Western Pharmacology Society, 1994, Volume: 37

    Topics: Adult; Aged; Anticonvulsants; Autoradiography; Cerebral Cortex; Felbamate; Glycine; Humans; Kynurenic Acid; Male; Middle Aged; Phenylcarbamates; Propylene Glycols; Receptors, Glycine; Strychnine

1994
Selective antagonism of the anticonvulsant effects of felbamate by glycine.
    European journal of pharmacology, 1994, Apr-21, Volume: 256, Issue:2

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Felbamate; Glycine; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Seizures

1994
Glycine reversal of felbamate hypoxic protection.
    Neuroreport, 1993, Volume: 4, Issue:7

    Topics: Animals; Anticonvulsants; Electric Stimulation; Electrophysiology; Felbamate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Neuroglia; Neurons; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Synapses

1993
Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Animals; Anticonvulsants; Apoptosis; Brain Ischemia; Cell Death; Cell Nucleus; Cell Survival; Cytoplasm; Disease Models, Animal; Felbamate; Gerbillinae; Glycine; Hippocampus; Injections, Intravenous; Neurons; Neuroprotective Agents; Phenylcarbamates; Propylene Glycols; Receptors, N-Methyl-D-Aspartate

1996
Excitoprotective effect of felbamate in cultured cortical neurons.
    Brain research, 1995, Dec-24, Volume: 705, Issue:1-2

    Topics: Animals; Anticonvulsants; Binding Sites; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Felbamate; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Strychnine

1995
Felbamate increases [3H]glycine binding in rat brain and sections of human postmortem brain.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Animals; Anticonvulsants; Autoradiography; Brain Chemistry; Excitatory Amino Acid Antagonists; Felbamate; Glycine; Humans; Kynurenic Acid; Male; Phenylcarbamates; Postmortem Changes; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

1998
Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Algorithms; Animals; Anticonvulsants; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Felbamate; Female; Glycine; Hydrogen-Ion Concentration; Membrane Potentials; Mutation; Oocytes; Patch-Clamp Techniques; Phenylcarbamates; Propylene Glycols; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Xenopus laevis

1999
Re: Mazarati et al. "...clinically available [antiepileptic drug] with a moderate affinity for the glycine site of the N-methyl-D-aspartate (NMDA) receptor".
    Epilepsia, 2000, Volume: 41, Issue:7

    Topics: Anticonvulsants; Epilepsy; Felbamate; Glycine; Humans; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2000
Characterization of the gating conformational changes in the felbamate binding site in NMDA channels.
    Biophysical journal, 2007, Jul-15, Volume: 93, Issue:2

    Topics: Animals; Animals, Newborn; Anticonvulsants; Binding Sites; Biophysical Phenomena; Biophysics; Felbamate; Glycine; In Vitro Techniques; Ion Channel Gating; Kinetics; N-Methylaspartate; Neurons; Phenylcarbamates; Propylene Glycols; Protein Conformation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2007