farnesol and squalene

farnesol has been researched along with squalene in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199042 (79.25)18.7374
1990's8 (15.09)18.2507
2000's0 (0.00)29.6817
2010's2 (3.77)24.3611
2020's1 (1.89)2.80

Authors

AuthorsStudies
Cornforth, J1
Agnew, WS; Popják, G1
Castillo, R; Ortiz de Montellano, PR; Vinson, W; Wei, JS1
Altman, LJ; Bertolino, A; Rilling, HC; Vasak, J1
Boar, RB; Damps, K1
Boparai, AS; Ortiz de Montellano, PR1
Edmond, J; Fogelman, AM; Popják, G; Seager, J1
Goldner, CM; Haug, JS; Melnykovych, G1
Djerassi, C; Silva, CJ; Wünsche, L1
Beedle, AS; Munday, KA; Wilton, DC1
Barnes, FJ; Porter, JW; Qureshi, AA; Semmler, EJ1
Carlson, JP; Kuehl, L; Muscio, F; Rilling, HC1
Gosselin, L1
Feldbruegge, DH; Krishna, G; Porter, JW1
Rilling, HC2
Rilling, HC; Sofer, SS1
Fairbairn, D; Frayha, GJ1
Epstein, WW; Rilling, HC1
Koyama, T; Ogura, K; Seto, S1
Popják, G1
Beytia, E; Briedis, A; Craig, MC; Dugan, RE; Feldbruegge, DH; Porter, JW; Qureshi, AA; Slakey, LL; Subbarayan, C1
Parker, T; Polito, A; Popják, G1
Stone, KJ; Strominger, JL1
Beytia, ED; Porter, JW; Qureshi, AA1
Benveniste, P; Coates, RM; Heintz, R; Robinson, WH1
Beytia, E; Porter, JW; Qureshi, AA2
Ness, GC; Porter, JW; Qureshi, N; Slakey, LL1
Cohen, P; Derksen, A1
Cornforth, JW; Cornforth, RH; Donninger, C; Popják, G; Ryback, G; Schroepfer, GJ1
Feldbruegge, DH; Krishna, G; Porter, JW; Whitlock, HW1
Graebe, JE1
Cornforth, JW; Etemadi, AH; Popják, G1
Clifford, K; Edmond, J; Popják, G; Williams, V1
Edmond, J; Popják, G; Williams, VP; Wong, SM1
Dugan, RE; Porter, JW1
Pennock, JF; Walton, MJ1
Barnes, FJ; Porter, JW; Qureshi, AA1
Benveniste, P; Hirth, L; Ourisson, G1
el-Ibrashy, MT; Mansour, MH1
Nakai, C; Suzue, G; Tanaka, S; Tsukada, K1
Bhavnani, BR1
Inoue, H; Korenaga, T; Koyama, T; Ogura, K; Sagami, H1
Corsini, A; Fumagalli, R; Gabbiani, G; Mazzotti, M; Paoletti, R; Raiteri, M; Soma, MR1
Prashad, M1
Favre, G; Miquel, K; Pradines, A1
Durham, SK; Flint, OP; Gregg, RE; Masters, BA1
Fisher, JE; Halasy, JM; Hughes, DE; Luckman, SP; Masarachia, PJ; Reszka, AA; Rodan, GA; Rogers, MJ; Russell, RG; Wesolowski, G1
DUVIVIER, J; GOSSELIN, L1
Hagelauer, N; Pabst, AM; Walter, C; Ziebart, T1
Fukushima, S; Minegaki, T; Morioka, C; Nishiguchi, K; Takanashi, H; Tsuji, S; Tsujimoto, M; Uno, J; Watanabe, A; Yamamoto, S1
Benítez-Mateos, AI; Hauer, B; Hegarty, E; Paradisi, F; Schneider, A1

Reviews

1 review(s) available for farnesol and squalene

ArticleYear
Conversion of mevalonic acid into prenyl hydrocarbons as exemplified by the synthesis of squalene.
    Biochemical Society symposium, 1970, Volume: 29

    Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Deuterium; Farnesol; Glycols; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mevalonic Acid; Models, Chemical; Models, Structural; Optical Rotatory Dispersion; Phosphoric Acids; Phosphorus Isotopes; Squalene; Stereoisomerism; Terpenes; Tritium; Yeasts

1970

Other Studies

52 other study(ies) available for farnesol and squalene

ArticleYear
Symmetry of squalene epoxidation in vivo.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1977, Nov-14, Volume: 199, Issue:1135

    Topics: Acetyl Coenzyme A; Animals; Cholesterol; Epoxy Compounds; Farnesol; Lanosterol; Liver; Mevalonic Acid; Rats; Squalene

1977
Squalene synthetase.
    Molecular and cellular biochemistry, 1979, Oct-15, Volume: 27, Issue:2

    Topics: Animals; Binding Sites; Detergents; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Kinetics; Microsomes, Liver; Models, Chemical; Models, Structural; NADP; Oxidoreductases; Phospholipids; Polyisoprenyl Phosphates; Sesquiterpenes; Solubility; Squalene; Substrate Specificity; Yeasts

1979
Squalene biosynthesis. Role of the 3-methyl group in farnesyl pyrophosphate.
    Journal of the American Chemical Society, 1976, May-12, Volume: 98, Issue:10

    Topics: Farnesol; Phosphoric Acids; Squalene

1976
Polyisoprenoid amphiphilic compounds as inhibitors of squalene synthesis and other microsomal enzymes.
    Biochimica et biophysica acta, 1978, Jul-25, Volume: 530, Issue:1

    Topics: Cytochrome Reductases; Farnesol; Glucose-6-Phosphatase; Isomerases; Lanosterol; Microsomes; Polyisoprenyl Phosphates; Saccharomyces cerevisiae; Squalene; Structure-Activity Relationship

1978
Resolution of 2,3-dihydrosqualene-2,3-diol, 10,11-dihydro-10,11-dihydroxyfarnesyl benzoate, and 6,7-dihydro-6,7-dihydroxygeranyl benzoate. Synthesis of (3R)- and (3S)-2,3-epoxy-2,3-dihydrosqualene.
    Journal of the Chemical Society. Perkin transactions 1, 1977, Issue:6

    Topics: Benzoates; Chromatography; Ethers, Cyclic; Farnesol; Hydroxylation; Squalene

1977
The squalene synthetase active site. Catalytic acceptance of 7- and 11- demethylfarnesyl pyrophosphates.
    Biochemical and biophysical research communications, 1976, May-23, Volume: 76, Issue:2

    Topics: Binding Sites; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Mass Spectrometry; Organophosphorus Compounds; Oxidoreductases; Saccharomyces cerevisiae; Squalene

1976
Abnormal induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in leukocytes from subjects with heterozygous familial hypercholesterolemia.
    The Journal of biological chemistry, 1975, Mar-25, Volume: 250, Issue:6

    Topics: Acetates; Adolescent; Adult; Alcohol Oxidoreductases; Enzyme Induction; Farnesol; Glutarates; Heterozygote; Humans; Hypercholesterolemia; Leukocytes; Lipids; Male; Mevalonic Acid; Middle Aged; Squalene; Sterols; Time Factors

1975
Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol.
    Biochemical and biophysical research communications, 1992, Jul-15, Volume: 186, Issue:1

    Topics: Acyclic Monoterpenes; Cell Division; Cell Line; Diglycerides; Dolichols; Dose-Response Relationship, Drug; Farnesol; Humans; Isomerism; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Phosphatidylcholines; Squalene; Terpenes

1992
Biosynthetic studies of marine lipids. 35. The demonstration of de novo sterol biosynthesis in sponges using radiolabeled isoprenoid precursors.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1991, Volume: 99, Issue:4

    Topics: Animals; Farnesol; Mevalonic Acid; Porifera; Squalene; Sterols; Tritium

1991
Studies on the biosynthesis of tetrahymanol in Tetrahymena pyriformis. The mechanism of inhibition by cholesterol.
    The Biochemical journal, 1974, Volume: 142, Issue:1

    Topics: Acetates; Alcohol Oxidoreductases; Carbon Radioisotopes; Cholesterol; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Diphosphates; Farnesol; Ligases; Mevalonic Acid; Oxygenases; Phosphoric Acids; Polycyclic Compounds; Squalene; Tetrahymena pyriformis; Triterpenes; Tritium

1974
Biosynthesis of prelycopersene pyrophosphate and lycopersene by squalene synthetase.
    The Journal of biological chemistry, 1973, Apr-25, Volume: 248, Issue:8

    Topics: Aluminum; Carbon Isotopes; Cations, Divalent; Chromatography, Gas; Chromatography, Thin Layer; Cyclopropanes; Farnesol; Kinetics; Ligases; Lithium; Mass Spectrometry; NAD; NADP; Optical Rotatory Dispersion; Phosphoric Acids; Squalene; Temperature; Terpenes

1973
Prequalene pyrophosphate. A normal intermediate in squalene biosynthesis.
    The Journal of biological chemistry, 1974, Jun-25, Volume: 249, Issue:12

    Topics: Animals; Butanols; Dimethylformamide; Dose-Response Relationship, Drug; Farnesol; Liver; Male; Methanol; Mevalonic Acid; Microsomes; NAD; NADP; Oxidation-Reduction; Phosphoric Acids; Rats; Saccharomyces cerevisiae; Squalene; Sterols; Tritium

1974
[Utilization of farnesyl pyrophosphate by rat liver microsomes in the absence of nicotinamide adenine dinucleotides].
    Archives internationales de physiologie et de biochimie, 1964, Volume: 72, Issue:2

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Diphosphates; Farnesol; In Vitro Techniques; Liver; Mevalonic Acid; Microsomes; NAD; NADP; Radiometry; Rats; Squalene

1964
An enzyme-bound intermediate in the conversion of farnesyl pyrophosphate to squalene.
    Biochemical and biophysical research communications, 1964, Volume: 14

    Topics: Chromatography, Gas; Diphosphates; Enzymes; Farnesol; Fatty Acids; Hydrocarbons; In Vitro Techniques; Ligases; Microsomes; Squalene

1964
A new intermediate in the biosynthesis of squalene.
    The Journal of biological chemistry, 1966, Jul-10, Volume: 241, Issue:13

    Topics: Alkenes; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Gas; Diphosphates; Farnesol; Saccharomyces; Squalene

1966
Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate.
    Journal of lipid research, 1969, Volume: 10, Issue:2

    Topics: Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Farnesol; Phosphoric Acids; Saccharomyces; Squalene; Terpenes; Thiourea; Tritium

1969
Lipid metabolism in helminth parasites--VI. Synthesis of 2-cis,6-trans farnesol by Hymenolepis diminuta (Cestoda).
    Comparative biochemistry and physiology, 1969, Volume: 28, Issue:3

    Topics: Acetates; Animals; Carbon Isotopes; Cestoda; Cholesterol; Chromatography, Gas; Farnesol; Glutarates; Invertebrate Hormones; Mevalonic Acid; Phosphoric Acids; Rats; Squalene; Stereoisomerism; Terpenes

1969
Studies on the mechanism of squalene biosynthesis. The structure of presqualene pyrophosphate.
    The Journal of biological chemistry, 1970, Sep-25, Volume: 245, Issue:18

    Topics: Alcohols; Aluminum; Chromatography, Gas; Chromatography, Ion Exchange; Cyclopropanes; Deuterium; Farnesol; Lithium; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphoric Acids; Saccharomyces; Spectrum Analysis; Squalene; Tritium

1970
Enzymic formation of squalene homologs from farnesyl Pyrophosphate homologs.
    Journal of the American Chemical Society, 1972, Jan-12, Volume: 94, Issue:1

    Topics: Animals; Carbon Isotopes; Cyclization; Diphosphates; Farnesol; Methylation; Microsomes, Liver; Squalene; Swine

1972
The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene.
    The Journal of biological chemistry, 1972, May-25, Volume: 247, Issue:10

    Topics: Acetates; Alcohol Oxidoreductases; Alkenes; Allyl Compounds; Animals; Carbon Isotopes; Carboxy-Lyases; Cholesterol; Circadian Rhythm; Dietary Fats; Farnesol; Fasting; Glutarates; Isomerases; Kinetics; Ligases; Liver; Male; Mevalonic Acid; Microsomes, Liver; Phosphoric Acids; Phosphotransferases; Rats; Squalene; Subcellular Fractions; Transferases

1972
Artificial substrates in squalene and sterol biosynthesis.
    The Journal of biological chemistry, 1972, Jun-10, Volume: 247, Issue:11

    Topics: Alkenes; Allyl Compounds; Animals; Carbon Isotopes; Cholesterol; Chromatography, Gas; Cyclization; Ethers, Cyclic; Farnesol; Homosteroids; Lanosterol; Liver; Mass Spectrometry; Models, Chemical; Phosphoric Acids; Rats; Silicon; Squalene; Sterols; Transferases; Tritium

1972
Inhibition of sterol biosynthesis by bacitracin.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:5

    Topics: Alkaline Phosphatase; Animals; Bacitracin; Carbon Isotopes; Depression, Chemical; Diphosphates; Escherichia coli; Farnesol; Liver; Male; Mevalonic Acid; Nitrophenols; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Squalene; Sterols; Terpenes; Tritium

1972
Squalene synthetase. I. Dissociation and reassociation of enzyme complex.
    Biochemical and biophysical research communications, 1972, Sep-05, Volume: 48, Issue:5

    Topics: Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis, Disc; Farnesol; Ligases; Macromolecular Substances; Molecular Weight; Phosphoric Acids; Saccharomyces; Saccharomyces cerevisiae; Squalene

1972
Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant.
    Biochemical and biophysical research communications, 1972, Dec-18, Volume: 49, Issue:6

    Topics: Acetates; Acetylation; Alcohols; Alkaline Phosphatase; Anhydrides; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Culture Techniques; Farnesol; Mevalonic Acid; Microsomes; NAD; Organophosphorus Compounds; Phosphoric Acids; Phytosterols; Plants; Squalene; Tritium

1972
Squalene synthetase. II. Purification and properties of bakers' yeast enzyme.
    The Journal of biological chemistry, 1973, Mar-10, Volume: 248, Issue:5

    Topics: Ammonium Sulfate; Carbon Isotopes; Carrier Proteins; Centrifugation, Density Gradient; Centrifugation, Zonal; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Drug Stability; Electrophoresis, Disc; Electrophoresis, Starch Gel; Farnesol; Glycerol; Half-Life; Ligases; Macromolecular Substances; Mercaptoethanol; Phosphoric Acids; Saccharomyces cerevisiae; Squalene; Sucrose; Surface-Active Agents

1973
Squalene synthetase. 3. Mechanism of the reaction.
    The Journal of biological chemistry, 1973, Mar-10, Volume: 248, Issue:5

    Topics: Acetamides; Buffers; Enzyme Activation; Ethylmaleimide; Farnesol; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Ligases; Magnesium; Manganese; Osmolar Concentration; Phosphates; Phosphoric Acids; Protein Binding; Saccharomyces cerevisiae; Squalene

1973
Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta.
    Journal of lipid research, 1973, Volume: 14, Issue:4

    Topics: Acetyl Coenzyme A; Alcohol Oxidoreductases; Alkenes; Animals; Aorta; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Paper; Coenzyme A; Farnesol; Glutarates; Hemiterpenes; Ligases; Mevalonic Acid; Multienzyme Complexes; Muscle, Smooth; Organophosphorus Compounds; Phosphoric Acids; Squalene; Subcellular Fractions; Swine

1973
Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro.
    The Journal of biological chemistry, 1973, Nov-10, Volume: 248, Issue:21

    Topics: Acetates; Animals; Autoradiography; Blood Platelets; Carbon Dioxide; Carbon Radioisotopes; Cholesterol; Dealkylation; Farnesol; Fatty Acids; Fatty Acids, Unsaturated; Humans; Lanosterol; Lipids; Liver; Mevalonic Acid; Phosphoric Acids; Rats; Squalene; Sterols

1973
Studies on the biosynthesis of cholesterol. XVII. The asymmetric synthesis of a symmetrical molecule.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1966, Jan-18, Volume: 163, Issue:993

    Topics: Animals; Cholesterol; Diphosphates; Farnesol; In Vitro Techniques; Rats; Squalene

1966
Enzymic conversion of farnesyl pyrophosphate to squalene.
    Archives of biochemistry and biophysics, 1966, Volume: 114, Issue:1

    Topics: Animals; Chromatography, Gas; Chromatography, Gel; Chromatography, Thin Layer; Diphosphates; Ethylmaleimide; Farnesol; In Vitro Techniques; Ligases; Liver; Magnesium; Manganese; NADP; Squalene; Swine; Terpenes

1966
Isoprenoid biosynthesis in a cell-free system from pea shoots.
    Science (New York, N.Y.), 1967, Jul-07, Volume: 157, Issue:3784

    Topics: Carbon Isotopes; Chromatography, Thin Layer; Farnesol; In Vitro Techniques; Lipids; Mevalonic Acid; NAD; NADP; Plants, Edible; Squalene; Terpenes

1967
Assay of the possible organization of particle-bound enzymes with squalene synthetase and squalene oxidocyclase systems.
    The Biochemical journal, 1969, Volume: 111, Issue:4

    Topics: Animals; Carbon Isotopes; Cholestanes; Farnesol; In Vitro Techniques; Ligases; Liver; Mixed Function Oxygenases; NADP; Squalene; Sterols; Swine; Tritium

1969
Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene.
    The Journal of biological chemistry, 1969, Apr-10, Volume: 244, Issue:7

    Topics: Alcohols; Alkenes; Animals; Carbon Isotopes; Chromatography; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Thin Layer; Crystallization; Crystallography; Diphosphates; Farnesol; Glycols; Liver; Magnetic Resonance Spectroscopy; Methods; Microsomes; NADP; Optical Rotatory Dispersion; Periodic Acid; Phosphorus; Rats; Saccharomyces; Spectrum Analysis; Squalene; Swine; Tritium

1969
Presqualene alcohol. Further evidence on the structure of a C 30 precursor of squalene.
    The Journal of biological chemistry, 1971, Oct-25, Volume: 246, Issue:20

    Topics: Acetates; Acylation; Alcohols; Alkenes; Aluminum; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Cyclopropanes; Deuterium; Diphosphates; Farnesol; Hydrolysis; Infrared Rays; Lithium; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes; Microsomes, Liver; Models, Structural; NADP; Optical Rotation; Ozone; Saccharomyces; Spectrophotometry; Squalene; Stereoisomerism; Terpenes; Tritium

1971
The effect of sterol carrier protein on squalene synthesis.
    Biochemical and biophysical research communications, 1972, Jan-31, Volume: 46, Issue:2

    Topics: Animals; Carrier Proteins; Chromatography, Gel; Diphosphates; Farnesol; Microsomes; Microsomes, Liver; NADP; Protein Binding; Proteins; Squalene; Sterols; Subcellular Fractions; Swine; Tritium; Yeasts

1972
Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:1

    Topics: Ammonium Sulfate; Animals; Carbon Isotopes; Catalysis; Chemical Precipitation; Chromatography, Gel; Farnesol; Kinetics; Ligases; Microsomes, Liver; Models, Chemical; Molecular Weight; NADP; Phosphoric Acids; Protein Binding; Squalene; Swine; Vibration

1972
Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates.
    The Biochemical journal, 1972, Volume: 127, Issue:3

    Topics: Alcohols; Animals; Annelida; Carbon Isotopes; Chromatography, Thin Layer; Cnidaria; Crustacea; Echinodermata; Farnesol; Fatty Alcohols; Invertebrates; Marine Biology; Mevalonic Acid; Mollusca; Porifera; Squalene; Sterols; Terpenes; Ubiquinone

1972
Lycopersene and prelycopersene pyrophosphate. Intermediates in carotene biosynthesis.
    The Journal of biological chemistry, 1972, Oct-25, Volume: 247, Issue:20

    Topics: Aluminum; Carbon Isotopes; Carotenoids; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Farnesol; Mass Spectrometry; NADP; Organophosphorus Compounds; Phosphoric Acids; Plants; Squalene; Yeasts

1972
[Biosynthesis of squalene with the help of microsomes originating from the tissue of tobacco cultivated in vitro].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1967, Nov-27, Volume: 265, Issue:22

    Topics: Culture Techniques; Farnesol; Mevalonic Acid; Microsomes; Nicotiana; Plant Extracts; Plants, Toxic; Squalene

1967
Hormonal action of certain biologically active compounds in Agrotis ypsilon larvae.
    Experientia, 1970, Oct-15, Volume: 26, Issue:10

    Topics: Animals; Antimetabolites; Depression, Chemical; Farnesol; Feeding Behavior; Herbicides; Imidazoles; Insecta; Larva; Plants, Toxic; Quaternary Ammonium Compounds; Ricinus; Squalene; Succinates; Triazines

1970
Presence of squalene in Staphylococcus.
    Archives of biochemistry and biophysics, 1968, Mar-11, Volume: 123, Issue:3

    Topics: Carbon Isotopes; Chromatography; Chromatography, Gas; Farnesol; Spectrum Analysis; Squalene; Staphylococcus; Steroids

1968
Oestrogen biosynthesis in the pregnant mare.
    The Journal of endocrinology, 1981, Volume: 89 Suppl

    Topics: Acetates; Alkenes; Androstenedione; Animals; Chemical Phenomena; Chemistry; Cholesterol; Dehydroepiandrosterone; Equilin; Estrogens; Farnesol; Female; Hemiterpenes; Horses; Maternal-Fetal Exchange; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Pregnancy; Pregnancy, Animal; Sesquiterpenes; Squalene; Tyrosine

1981
Phosphorylation of farnesol by a cell-free system from Botryococcus braunii.
    Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2

    Topics: Cytidine Triphosphate; Eukaryota; Farnesol; NAD; NADP; Phosphorylation; Squalene; Triterpenes

1994
Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase.
    Atherosclerosis, 1993, Volume: 101, Issue:1

    Topics: Acyclic Monoterpenes; Animals; Aorta; Cell Division; Cells, Cultured; Cholesterol; Diterpenes; Dose-Response Relationship, Drug; Farnesol; Fatty Acids, Monounsaturated; Femoral Artery; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Squalene; Terpenes

1993
Amidinium cation as a mimic of allylic carbocation: synthesis and squalene synthetase inhibitory activity of an amidinium analog of a carbocation intermediate.
    Journal of medicinal chemistry, 1993, Mar-05, Volume: 36, Issue:5

    Topics: Amidines; Animals; Cations; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Microsomes, Liver; Rats; Squalene

1993
Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells.
    Biochemical and biophysical research communications, 1996, Aug-23, Volume: 225, Issue:3

    Topics: Actins; Acyclic Monoterpenes; Apoptosis; Cholesterol; Cytoskeleton; Desmosterol; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Squalene; Terpenes; Tumor Cells, Cultured

1996
Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
    Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anticholesteremic Agents; Butylamines; Cells, Cultured; Cholesterol; Diterpenes; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Muscle, Skeletal; Pravastatin; Pregnancy; Prodrugs; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Squalene; Sulfonic Acids

1997
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-05, Volume: 96, Issue:1

    Topics: Alendronate; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Cholesterol; Clodronic Acid; Diterpenes; Enzyme Activation; Farnesol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Osteoclasts; Protein Kinases; Rabbits; Skull; Squalene

1999
[BIOSYNTHESIS OF FARNESOL PYROPHOSPHATE AND SQUALENE FROM 2-C14-MEVALONIC ACID BY CELL FRACTIONS OF ADRENAL HOMOGENATE].
    Bulletin de la Societe de chimie biologique, 1965, Volume: 47

    Topics: Adrenal Glands; Animals; Cattle; Chromatography; Diphosphates; Farnesol; Ligases; Metabolism; Mevalonic Acid; Microsomes; NADP; Research; Squalene; Terpenes

1965
Bisphosphonates inhibit cell functions of HUVECs, fibroblasts and osteogenic cells via inhibition of protein geranylgeranylation.
    Clinical oral investigations, 2015, Volume: 19, Issue:5

    Topics: Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cell Movement; Cell Survival; Cells, Cultured; Cyclohexenes; Diphosphonates; Diterpenes; Endothelial Cells; Eugenol; Farnesol; Fibroblasts; Humans; Imidazoles; Limonene; Menthol; Osteogenesis; Protein Prenylation; Recurrence; Squalene; Terpenes; Umbilical Veins; Zoledronic Acid

2015
Effects of bisphosphonates on human esophageal squamous cell carcinoma cell survival.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2016, Volume: 29, Issue:6

    Topics: Annexins; Apoptosis; Bone Density Conservation Agents; Carcinoma, Squamous Cell; Caspase 3; Caspase 7; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cyclin D1; Diphosphonates; Diterpenes; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Farnesol; G1 Phase Cell Cycle Checkpoints; Humans; Squalene

2016
Spheroplasts preparation boosts the catalytic potential of a squalene-hopene cyclase.
    Nature communications, 2022, 10-21, Volume: 13, Issue:1

    Topics: Acetone; Farnesol; Intramolecular Transferases; Spheroplasts; Squalene; Terpenes

2022