Page last updated: 2024-08-26

equol and genistein

equol has been researched along with genistein in 195 studies

Research

Studies (195)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.03)18.7374
1990's28 (14.36)18.2507
2000's86 (44.10)29.6817
2010's64 (32.82)24.3611
2020's15 (7.69)2.80

Authors

AuthorsStudies
Ernst, B; Lill, MA; Vedani, A; Winiger, F1
Chen, JZ; Khan, MZI; Nazli, A; Uzair, M1
Adlercreutz, H; Bannwart, C; Brunow, G; Fotsis, T; Hase, T; Wähälä, K1
Babin, P; Bennetau, B; Dunogues, J; Le Menn, F; Pelissero, C1
Ewing, LL; Juniewicz, PE; Moser, A; Pallante Morell, S1
Evans, BA; Griffiths, K; Morton, MS1
Campbell, DR; Kirkman, LM; Lampe, JW; Martini, MC; Slavin, JL1
Hutchins, AM; Lampe, JW; Slavin, JL1
Campbell, DR; Hutchins, AM; Lampe, JW; Martini, MC; Slavin, JL1
Adlercreutz, H; Markkanen, H; Watanabe, S1
Griffiths, K; Morton, MS; Wahlqvist, ML; Wilcox, G1
Joannou, GE; Kelly, GE; Nelson, C; Reeder, AY; Waring, MA1
Adlercreutz, H; Garey, J; Gurpide, E; Markiewicz, L1
Adlercreutz, H; Carson, M; Loukovaara, M; Palotie, A1
Anderson, KE; Grady, JJ; Lu, LJ; Marshall, MV; Ramanujam, VM1
Duwe, G; Zava, DT1
Chipman, JK; Gescher, A; Helsby, NA; Kerr, D; Williams, J1
Bursill, DB; King, RA1
Chipman, JK; Gescher, A; Helsby, NA; Kerr, D1
Frawley, LS; Willard, ST1
Head, RJ; King, RA; Mano, MM1
Adlercreutz, H; Akhmedkhanov, A; Toniolo, P; Zeleniuch-Jacquotte, A1
Brüggemann-Rotgans, IE; Kardinaal, AF; Morton, MS; van Beresteijn, EC1
Alda, JO; Giménez, I; Lou, JM; Martínez, RM; Mayoral, JA1
Cai, J; Heubi, JE; Setchell, KD; Zimmer-Nechemias, L1
King, RA1
Dubey, RK; Gillespie, DG; Imthurn, B; Jackson, EK; Keller, PJ; Rosselli, M1
Custer, LJ; Dai, Q; Franke, AA; Jin, F; Shu, XO; Wen, WQ; Zheng, W1
Bundred, NJ; Harding, C; Hargreaves, DF; Howell, A; Morton, MS; Potten, CS; Roberts, SA; Shaw, LE1
Ghazali, RA; Waring, RH1
Arora, A; Byrem, TM; Nair, MG; Strasburg, GM1
Adlercreutz, H; Arai, Y; Eboshida, A; Kimira, M; Sato, Y; Uehara, M; Watanabe, S1
Izumi, T; Kataoka, S; Kikuchi, M; Obata, A; Piskula, MK; Saito, M; Tobe, K; Yamakoshi, J1
Breinholt, V; Brouwer, C; Hossaini, A; Nielsen, E; Svendsen, GW1
Hodis, HN; Hwang, J; Sevanian, A; Ursini, F1
Campbell, MJ; Hartley, JA; Leathem, AJ; Sierens, J; Woodside, JV1
Kinjo, J1
Brown, NM; Setchell, KD1
Collins, AR; Duthie, SJ; Mitchell, JH1
Alworth, WL; Hopkins, NE; Rajnarayanan, RV; Rowley, CW1
Knoll, E; Kohen, F; Somjen, D; Stern, N1
Cheung, TF; Chung, TK; Haines, CJ; Hjelm, NM; Loong, EP; Roach, VJ; Waring, MA1
Adlercreutz, H; Ishimi, Y; Morohashi, T; Ohta, A; Sakai, K; Takasaki, M; Uehara, M1
Arisaka, O; Evans, BA; Miyake, N; Morgan, LD; Morton, MS1
Hedlund, TE; Johannes, WU; Miller, GJ1
Avades, T; Botting, NP; Brashear, WT; Brown, NM; Cassidy, A; Desai, P; Faughnan, MS; Oldfield, MF; Setchell, KD; Wolfe, BE; Zimmer-Nechemias, L1
Collins, P; Liew, R; MacLeod, KT; Williams, JK1
Bingham, SA; Botting, NP; Fryatt, T; Grace, PB; Oldfield, MF; Taylor, JI1
Hodis, HN; Hwang, J; Morazzoni, P; Sevanian, A; Wang, J1
Meydani, M; Zubik, L1
Andre, F; Antignac, JP; Cariou, R; Cravedi, JP; Le Bizec, B1
Balch, GC; Kiparissis, Y; Metcalfe, CD; Metcalfe, TL1
CARTER, AL; CAYEN, MN; COMMON, RH1
Doerge, DR; Helferich, WG; Ju, YH; Katzenellenbogen, BS; Katzenellenbogen, JA; Muthyala, RS; Sheng, S; Williams, LD1
Ah-Singh, E; Brown, J; Cassidy, A; Faughnan, MS; Hawdon, A; Millward, DJ1
Clarke, DB; Hoey, L; Lloyd, AS; Rowland, IR; Wiseman, H1
Aihara, H; Hong, T; Ikehara, T; Ito, T; Kim, MY; Kraus, WL; Muramatsu, M; Nakagawa, T; Pan, W; Takebe, M; Yasui, K1
Akaza, H; Fujioka, T; Hirao, Y; Kim, WJ; Miyanaga, N; Mori, M; Naito, S; Pantuck, AJ; Song, JM; Takashima, N; Tsukamoto, T1
Blondeel, P; Bracke, ME; De Keukeleire, D; Depypere, HT; Goeman, J; Heyerick, A; Maubach, J; Van der Eycken, J1
Degen, GH; Di Virgilio, AL; Iwami, K; Kahl, R; Wätjen, W1
Soidinsalo, O; Wähälä, K1
Acworth, I; Gamache, P; Ouchi, K; Watanabe, S1
Bugel, S; Cassidy, A; de Pascual-Teresa, S; Hallund, J; Schroot, J; Talbot, D; Williams, CM1
Melby, MK; Watanabe, S; Whitten, PL; Worthman, CM1
Campbell, MJ; Denholm, EE; Honour, JW; Leathem, AJ; Morton, MS; Newton, L; Woodside, JV; Young, IS1
Alexander, FE; Bolton-Smith, C; Heald, CL; Morton, MS; Ritchie, MR2
Bingham, SA; Day, NE; Doody, D; Dowsett, M; Dunning, AM; Folkerd, E; Grace, PB; Khaw, KT; Low, YL; Luben, RN; Mulligan, AA; Scollen, S; Taylor, JI; Wareham, NJ; Welch, AA1
Anderson, KE; Grady, JJ; Lu, LJ; Nagamani, M; Nhan, S1
Albertazzi, P; Bottazzi, M; Steel, SA1
Brandolini, M; Coxam, V; Davicco, MJ; Guy, L; Manach, C; Mathey, J; Morand, C; Rémésy, C; Védrine, N1
Cooper, S; Delclos, KB; Doerge, DR; Fu, X; Latendresse, JR; Twaddle, NC1
Clotfelter, ED; Rodriguez, AC1
Kulling, SE; Rüfer, CE1
Arao, Y; Horiguchi, H; Kayama, F; Oguma, E; Sun, SJ; Yamada, K; Zhao, JH1
Dusza, L; Kaminska, B; Opalka, DM; Piskula, MK; Puchajda-Skowronska, H1
Chandramouli, GV; Hursting, SD; Kim, YS; Lavigne, JA; Perkins, SN; Takahashi, Y; Wang, TT1
Lau, TY; Leung, LK1
Harada, K; Ishikawa, F; Kano, M; Sawada, S; Takayanagi, T1
Hara, H; Nishimukai, M; Shigematsu, N; Tamura, A1
Franke, AA; Hebshi, S; Maskarinec, G; Yamakawa, R1
Iwasa, S; Nagata, C; Sahashi, Y; Shimizu, H; Shiraki, M; Uchiyama, S; Ueno, T; Urata, K1
Gilad, LA; Schwartz, B; Tirosh, O1
Bonorden, MJ; Feirtag, JM; Hamilton-Reeves, JM; Kurzer, MS; McMullen, MH; Phipps, WR; Wangen, KE1
Hall, MC; McCormack, T; O'Brien, B1
Dusza, L; Kamińska, B; Opałka, M; Puchajda-Skowrońska, H1
Adlercreutz, H; Barnard, G; Bugel, S; Cassidy, A; Dadd, T; Kohen, F; Marlin, S; Ogborne, RM; Piron, J; Powell, J; Talbot, DC1
Bennetau-Pelissero, C; Coxam, V; Davicco, MJ; Fokialakis, N; Horcajada, MN; Kati-Coulibaly, S; Lamothe, V; Lebecque, P; Mardon, J; Mathey, J; Mitakou, S; Puel, C1
Blaszkewicz, M; Bolt, HM; Degen, GH; Moors, S1
Chilibeck, PD; Vatanparast, H1
Constantinou, AI; Lim, SB; Tonetti, DA; Zhang, Y; Zhao, H1
Artur, Y; Bennetau-Pelissero, C; Bergès, R; Canivenc-Lavier, MC; Chevalier, J; Coxam, V; Davicco, MJ; Desmetz, C; Jover, E; Phrakonkham, P; Pinnert, MF1
Benedetta Donati, M; Cerletti, C; Evangelista, V; Krauze-Brzósko, K; Manarini, S; Martelli, N; Pecce, R; Rotondo, S1
Vastag, B1
Jackman, KA; Sobey, CG; Woodman, OL1
Janssen, LJ; Lippton, H; Liu, C; Tazzeo, T1
Appt, S; Clarkson, TB; Mikkola, TS; Tikkanen, MJ; Törmälä, RM; Ylikorkala, O1
Franke, AA; Hebshi, SM; Kagihara, J; Maskarinec, G; Watts, K1
Burch, JA; Lin, JY; Monteiro-Riviere, NA; Tournas, JA; Zielinski, J1
Chan, J; Franke, A; Fraser, GE; Jaceldo-Siegl, K; Sabaté, J1
Anai, S; Chang, M; Hou, W; Pendleton, JM; Rosser, CJ; Shiverick, KT; Tan, WW1
Botting, N; Darbre, PD; Mills, S; Pope, GS; Pugazhendhi, D; Watson, KA1
Ehrich, M; Purup, S; Sørensen, IF1
Bah, M; Brzezicka, E; Korzekwa, A; Piskula, MK; Siemieniuch, MJ; Skarzynski, DJ; Woclawek-Potocka, I1
Garrido, A; Muñoz, Y; Valladares, L1
Cline, JM; Durant, P; Leone-Kabler, S; Register, TC; Scott, LM; Townsend, A; Wood, CE1
Asthana, S; Atwood, CS; Barnet, JH; Carlsson, CM; Gleason, CE; Johnson, SC; Meade, SA; Ries, ML; Setchell, KD1
Bennetau-Pelissero, C; Carreau, C; Flouriot, G; Potier, M1
Blaut, M; Braune, A; Matthies, A1
Kruger, MC; Loots, du T; Moughan, PJ; Poulsen, RC1
Brooks, JD; Feldman, D; Franke, AA; Gardner, CD; Liu, JP; Oelrich, B1
Daub, F; Kolios, L; Rack, T; Sehmisch, S; Stuermer, EK; Stuermer, KM; Tezval, M1
Li, Y; Moore, DD; Ricketts, ML; Ross-Viola, JS; Shay, NF1
Franke, AA; Hebert, JR; Hurley, TG; Kurzer, MS; Sepkovic, DW; Teas, J1
Du, J; Hu, C; Li, Z; Liu, H; Liu, Q; Qi, H; Wang, S; Wang, X1
Cooke, GM; Gilani, GS; Robertson, P; Sepehr, E1
Akaza, H; Chihara, Y; Fujimoto, K; Hirao, Y; Hirayama, A; Miyanaga, N; Tanaka, M; Tanaka, N; Torimoto, K; Yoneda, T1
Kolios, L; Rack, T; Sehmisch, S; Seidlová-Wuttke, D; Stuermer, EK; Stuermer, KM; Tezval, M; Wuttke, W1
Bolca, S; Bracke, M; De Keukeleire, D; Depypere, H; Heyerick, A; Possemiers, S; Verstraete, W; Wyns, C1
Seidlova-Wuttke, D; Thielemann, A; Wuttke, M; Wuttke, W1
Carpenter, RE; Clotfelter, ED; McNitt, MM; Summers, CH1
Erren, M; Kolios, L; Sehmisch, S; Seidlova-Wuttke, D; Stuermer, EK; Stuermer, KM; Tezval, M; Wuttke, W1
Jarry, H; Maehlmeyer, S; Sehmisch, S; Stuermer, EK; Stuermer, KM; Tezval, M; Uffenorde, J1
Akingbemi, BT; Chu, YH; Ge, RS; Hu, GX; Zhao, BH; Zheng, ZQ; Zhou, HY1
Ma, Y; Schreihofer, DA; Sullivan, JC1
Belles, CA; Brown, NM; Kim, MO; Lindley, SL; Setchell, KD; Witte, DP; Zimmer-Nechemias, L1
Bennett, FI; Jackson, MD; McFarlane-Anderson, ND; Simon, GA; Walker, SP1
Blaszkewicz, M; Buyken, AE; Degen, GH; Remer, T; Shi, L1
deVere White, RW; Fujii, H; Hackman, RM; Soares, SE; Stapp, EC; Tsodikov, A1
Becker, L; Bucheli, TD; Hoerger, CC; Hungerbühler, K; Praplan, AP; Wettstein, FE1
Hori, S; Nakagawa, H; Tamura, M1
Frankenfeld, CL1
Furoku, S; Hosaka, T; Nakamoto, M; Nishioka, Y; Sakai, T; Shuto, E; Sone, S1
Azlan, A; Haron, H; Ismail, A; Peng, LS; Shahar, S1
Krol, W; Szliszka, E1
Cooke, GM; Curran, I; Dahiya, J; Dyck, M; Fan, L; Farmer, C; Gilani, GS; Nicolidakis, H; Robertson, P; Sepehr, E1
Bah, MM; Boruszewska, D; Kowalczyk-Zieba, I; Piotrowska-Tomala, KK; Piskula, MK; Siemieniuch, MJ; Skarzynski, DJ; Woclawek-Potocka, I1
Blaut, M; Braune, A; Loh, G; Matthies, A1
Amer, DA; Jähne, M; Kretzschmar, G; Vollmer, G; Weigt, C1
Kim, YH; Kumazoe, M; Tachibana, H; Tsukamoto, S; Yamada, K; Yamashita, S1
Chang, SH; Cho, LY; Choi, BY; Han, DS; Kang, D; Kim, YS; Ko, KP; Ma, SH; Park, SK; Shin, A; Shin, HR; Song, KS; Yang, JJ; Yoo, KY1
Kim, Y; Lee, S; Yum, T1
Blaut, M; Braune, A; Engst, W; Matthies, A; Schröder, C1
Kelly, LA; Norris, LA; O'Leary, JJ; Seidlova-Wuttke, D; Wuttke, W1
Bahmani, M; Dehghani, AA; Hosseini, SA; Sudagar, M; Yazdani, MA; Yousefi Jourdehi, A1
Cleveland, BM1
Geelen, A; Hollman, PC; Mensink, M; Schouten, EG; van der Velpen, V; van Nielen, M; Van't Veer, P1
Chang, SH; Cho, LY; Choi, BY; Han, DS; Kang, D; Kim, HJ; Kim, YS; Ko, KP; Ma, SH; Park, SK; Shin, A; Shin, HR; Song, KS; Yang, JJ; Yoo, KY1
Dietze, JE; Kullman, SW; Lee, B; Meyer, MT; Williams, CM; Worley-Davis, L; Yost, EE1
Afman, LA; Geelen, A; Hollman, PC; Schouten, EG; van 't Veer, P; van der Velpen, V1
Fuller, S; Gunderson, G; Iwashita, S; Lampe, JW; Newton, KM; Qu, C; Reed, SD; Uchiyama, S; Ueno, T1
Morales-Gutiérrez, FJ; Rodriguez-Mateos, A; Spencer, JP; Toro-Funes, N; Veciana-Nogués, MT; Vidal-Carou, MC1
Ahn, Y; Kim, CS; Kim, SS; Kim, YJ; Ko, KP; Lim, YK; Park, JK; Park, SJ; Yoo, KY1
Beydoun, HA; Jeng, HA; Kantaria, K1
Belosay, A; Doerge, DR; Hartman, JA; Helferich, WG; Song, H; Wang, W; Yang, X; Zhang, Y1
Liu, J; Xie, B; Xie, D; Zhan, X; Zhang, S; Zhang, Z1
Chedraui, P; Hobiger, S; Imhof, M; Jungbauer, A; Laschitz, T; Lipovac, M; Pfitscher, A1
Barnes, S; Jackson, GS; Martin, BR; McCabe, GP; McCabe, L; Pawlowski, JW; Peacock, M; Weaver, CM1
Cerundolo, R; Court, MH; Redmon, JM; Shrestha, B1
Álvarez-Buylla, JR; Cuesta, I; Delgado, S; Guadamuro, L; Mayo, B; Redruello, B1
Kelly, LA1
Sareddy, GR; Vadlamudi, RK1
Koh, WP; Lee, BL; Ong, CN; Pan, A; Talaei, M; van Dam, RM; Yuan, JM1
Ali Mohd, M; Hod, R; Husain, R; Kouidhi, W1
Fujii, S; Inoue, H; Ishimi, Y; Katsumata, S; Kikkawa, Y; Machida, M; Takahashi, N; Uehara, M1
Aresta, A; Calvello, R; Cianciulli, A; Clodoveo, ML; Corbo, F; Franchini, C; Panaro, MA; Salvatore, R; Trapani, A; Zambonin, C1
Churchwell, MI; Doerge, DR; Fleck, SC; Teeguarden, JG1
Abiru, Y; Goto, Y; Iwasa, S; Konishi, K; Mizuta, F; Nagata, C; Shiraki, M; Tamura, T; Tsuji, M; Uchiyama, S; Ueno, T; Wada, K1
Akasaka, H; Akaza, H; Fukuta, F; Masumori, N; Miura, T; Mori, M; Moriyama, K; Nagata, Y; Ohnishi, H; Saitoh, S; Sugiyama, Y; Takayanagi, A; Tsuji, H; Tsukamoto, T1
Lee, NK; Paik, HD1
Belcher, SM; Burton, CC; Cookman, CJ; Kirby, M; Miranda, GL; Saeed, FO; Wray, KE1
Brinton, RD; Chen, YL; Franke, AA; Hernandez, G; Mack, WJ; Schneider, LS; Zhao, L1
Choi, KY; Kazlauskas, RJ; Kim, BG; Kim, EJ; Kim, J; Lee, PG; Lee, SH1
Chen, R; Dong, Y; Ge, F; Ge, RS; Shan, Y; Sun, J; Sun, W; Wang, Z; Zhu, Q1
Ebihara, A; Goshima, T; Inagaki, M; Kato, Y; Kawada, Y; Kuwata, K; Niwa, T; Sakurada, O; Sawamura, R; Suzuki, T; Yamaguchi, K; Yanase, E; Yokoyama, SI1
Allen, NE; Appleby, PN; Boeing, H; Drake, I; Gil, L; Gislefoss, RE; Johansson, A; Key, TJ; Khaw, KT; Kubo, T; Kyrø, C; Landberg, R; Langseth, H; Luben, RN; Mikami, K; Murphy, N; Nilsson, LM; Ozasa, K; Perez-Cornago, A; Ricceri, F; Sawada, N; Sonestedt, E; Stattin, P; Tamakoshi, A; Travis, RC; Trichopoulou, A; Tsilidis, KK; Tsugane, S; Wallström, P1
Froemming, GRA; Fuad, SBSA; Ismail, ABM; Muid, S; Thent, ZC1
Bosland, MC; Eskra, JN; Schlicht, MJ1
Fickler, A; Rimbach, G; Schulz, C; Staats, S1
Brinton, RD; Chen, YL; Franke, AA; Hernandez, G; Mack, WJ; Pawluczyk, S; Schneider, LS; Zhao, L1
Dadáková, K; Kašparovská, J; Kašparovský, T; Křížová, L1
Chen, YM; Deng, YY; Dong, HL; Tang, XY; Wang, C; Zhang, ZQ; Zhong, QW1
Bravo, D; Landete, JM; Peirotén, Á1
Brinton, RD; Hernandez, G; Mack, WJ; Schneider, LS; Wang, Y; Yin, F1
Doerge, DR; Helferich, WG; Hughes, JR; Iwaniec, UT; Song, H; Turner, RT1
Akiyama, H; Echikawa, M; Mochizuki, M; Niwa, T; Osawa, T; Yokoyama, SI1
Higuchi, T; Nakano, S; Nishi, A; Ono, M; Takeshima, M1
Chiba, T; Kohda, F; Kono, M; Nagai, T; Nakahara, T1
Landete, JM; Langa, S1
Bobrowska-Korczak, B; Figat, R; Kiss, AK; Stanisławska, IJ1
Chen, ZK; Ma, DF; Wang, Y; Yu, X; Zou, YQ1
Betschler, A; Früholz, R; Grgic, D; Marko, D; Novak, B; Varga, E1
Chen, Y; Yang, F1
Gao, F; Guan, H; Li, J; Liang, J; Lu, Z; Teng, F; Tian, X; Wang, J; Wang, X1
Ghimire, S; Giri, S; Mangalam, AK; Rashid, F1

Reviews

11 review(s) available for equol and genistein

ArticleYear
An overview on Estrogen receptors signaling and its ligands in breast cancer.
    European journal of medicinal chemistry, 2022, Nov-05, Volume: 241

    Topics: Breast Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Ligands; Male; Receptors, Estrogen

2022
Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life.
    The American journal of clinical nutrition, 1998, Volume: 68, Issue:6 Suppl

    Topics: Adult; Animals; Cattle; Chromans; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Equol; Estrogens, Non-Steroidal; Female; Genistein; Humans; Infant; Infant Food; Infant, Newborn; Isoflavones; Milk, Human; Monoamine Oxidase Inhibitors; Soybean Proteins

1998
[Phytoestrogens].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:12

    Topics: Bacteria; Chromans; Digestive System; Equol; Estrogens, Non-Steroidal; Female; Gene Expression; Genistein; Humans; Isoflavones; Myocardial Ischemia; Neoplasms; Osteoporosis, Postmenopausal; Phytoestrogens; Plant Preparations; Receptors, Estrogen

2000
Does the effect of soy phytoestrogens on bone in postmenopausal women depend on the equol-producing phenotype?
    Nutrition reviews, 2007, Volume: 65, Issue:6 Pt 1

    Topics: Bone Density; Equol; Female; Gastrointestinal Tract; Genistein; Glycine max; Humans; Isoflavones; Middle Aged; Osteoporosis, Postmenopausal; Phenotype; Phytoestrogens; Postmenopause

2007
Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights.
    Current medicinal chemistry, 2007, Volume: 14, Issue:26

    Topics: Animals; Antioxidants; Endothelial Cells; Equol; Genistein; Humans; Hypertension; Isoflavones; Nitric Oxide Synthase; Potassium Channels; Soy Foods; Stroke; Vasodilation

2007
Gene polymorphisms in the ornithine decarboxylase-polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:3

    Topics: 4-Butyrolactone; Adenosylmethionine Decarboxylase; Asian People; Case-Control Studies; Equol; Gene-Environment Interaction; Genistein; Humans; Isoflavones; Lignans; Multicenter Studies as Topic; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Phytoestrogens; Polyamines; Polymorphism, Single Nucleotide; Stomach Neoplasms

2015
Cancer therapy using natural ligands that target estrogen receptor beta.
    Chinese journal of natural medicines, 2015, Volume: 13, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Equol; Estrogen Receptor beta; Flavanones; Genistein; Glycine max; Glycyrrhiza; Humans; Ligands; Neoplasms; Phytotherapy; Plant Extracts

2015
Bioconversion Using Lactic Acid Bacteria: Ginsenosides, GABA, and Phenolic Compounds.
    Journal of microbiology and biotechnology, 2017, May-28, Volume: 27, Issue:5

    Topics: Bacteria; beta-Galactosidase; beta-Glucosidase; Bifidobacterium; Cultured Milk Products; Equol; Fermentation; Food Microbiology; gamma-Aminobutyric Acid; Genistein; Ginsenosides; Isoflavones; Lactic Acid; Lactobacillus; Lactobacillus plantarum; Phenols; Streptococcus thermophilus

2017
Circulating isoflavone and lignan concentrations and prostate cancer risk: a meta-analysis of individual participant data from seven prospective studies including 2,828 cases and 5,593 controls.
    International journal of cancer, 2018, 12-01, Volume: 143, Issue:11

    Topics: Aged; Case-Control Studies; Equol; Europe; Genistein; Humans; Isoflavones; Japan; Lignans; Male; Middle Aged; Phytoestrogens; Prospective Studies; Prostatic Neoplasms; Risk Factors

2018
Isoflavones.
    Molecules (Basel, Switzerland), 2019, Mar-19, Volume: 24, Issue:6

    Topics: Animals; Equol; Genistein; Humans; Isoflavones; Phytoestrogens

2019
Bacterial metabolism as responsible of beneficial effects of phytoestrogens on human health.
    Critical reviews in food science and nutrition, 2020, Volume: 60, Issue:11

    Topics: Bacteria; Equol; Gastrointestinal Microbiome; Genistein; Humans; Hydrolyzable Tannins; Isoflavones; Lignans; Phytoestrogens

2020

Trials

26 trial(s) available for equol and genistein

ArticleYear
Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets.
    Nutrition and cancer, 1995, Volume: 24, Issue:1

    Topics: 4-Butyrolactone; Adult; Chromans; Colon; Cross-Over Studies; Diet; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Sex Characteristics; Vegetables

1995
Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products.
    Journal of the American Dietetic Association, 1995, Volume: 95, Issue:5

    Topics: 4-Butyrolactone; Adult; Chromans; Cross-Over Studies; Defecation; Diet; Equol; Estrogens; Estrogens, Non-Steroidal; Fermentation; Food Handling; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Taste

1995
Vegetables, fruits, and legumes: effect on urinary isoflavonoid phytoestrogen and lignan excretion.
    Journal of the American Dietetic Association, 1995, Volume: 95, Issue:7

    Topics: Adult; Chromans; Cross-Over Studies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Energy Intake; Equol; Estrogens, Non-Steroidal; Fabaceae; Female; Flavonoids; Fruit; Genistein; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Plants, Medicinal; Vegetables

1995
Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:11

    Topics: Adult; Apolipoproteins; Apolipoproteins D; Body Fluids; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Genistein; Glycine max; Humans; Isoflavones; Nipples; Phytoestrogens; Plant Preparations; Proteins; Soybean Proteins; Suction; Trefoil Factor-1; Tumor Suppressor Proteins

1999
Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:2

    Topics: Adult; Biological Availability; Carbon Isotopes; Chromans; Cohort Studies; Dose-Response Relationship, Drug; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Half-Life; Humans; Isoflavones; Mass Spectrometry; Metabolic Clearance Rate; Middle Aged; Premenopause; Reproducibility of Results; Soybean Proteins

2003
Bioavailability of soybean isoflavones from aglycone and glucoside forms in American women.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:6

    Topics: Adult; Area Under Curve; Biological Availability; Chromans; Double-Blind Method; Equol; Female; Genistein; Glycine max; Humans; Isoflavones; Middle Aged; Time Factors; United States

2003
Urinary isoflavone kinetics: the effect of age, gender, food matrix and chemical composition.
    The British journal of nutrition, 2004, Volume: 91, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Equol; Female; Genistein; Humans; Isoflavones; Male; Middle Aged; Nutritive Value; Postmenopause; Premenopause; Sex Characteristics; Soy Foods

2004
Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids.
    Obstetrics and gynecology, 2004, Volume: 103, Issue:5 Pt 1

    Topics: Adult; Body Fluids; Breast; Dietary Supplements; Double-Blind Method; Equol; Genistein; Humans; Isoflavones; Middle Aged; Phytoestrogens; Plant Preparations; Soy Foods; Tissue Distribution

2004
Effect of a soymilk supplement containing isoflavones on urinary F2 isoprostane levels in premenopausal women.
    Nutrition and cancer, 2005, Volume: 53, Issue:1

    Topics: Adult; Age Factors; Aging; Breast Neoplasms; Cross-Over Studies; Dietary Supplements; Dose-Response Relationship, Drug; Equol; F2-Isoprostanes; Female; Genistein; Humans; Isoflavones; Lipid Peroxidation; Premenopause; Soy Milk

2005
Effect of pure genistein on bone markers and hot flushes.
    Climacteric : the journal of the International Menopause Society, 2005, Volume: 8, Issue:4

    Topics: Biomarkers; Collagen; Collagen Type I; Cross-Over Studies; Equol; Female; Genistein; Hot Flashes; Humans; Isoflavones; Middle Aged; Osteocalcin; Ovary; Peptides; Postmenopause; Ultrasonography; Uterus

2005
Urinary isoflavonoid excretion and soy consumption in three generations of Japanese women in Hawaii.
    European journal of clinical nutrition, 2007, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Asian; Chromatography; Cross-Over Studies; Equol; Female; Flavonoids; Genistein; Hawaii; Humans; Isoflavones; Japan; Mass Spectrometry; Middle Aged; Soy Foods; Soy Milk

2007
Consumption of Lactobacillus acidophilus and Bifidobacterium longum does not alter phytoestrogen metabolism and plasma hormones in men: a pilot study.
    Journal of alternative and complementary medicine (New York, N.Y.), 2006, Volume: 12, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Androstane-3,17-diol; Androstenedione; Bifidobacterium; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Equol; Genistein; Hormones; Humans; Isoflavones; Lactobacillus acidophilus; Leptin; Male; Phytoestrogens; Pilot Projects; Probiotics; Sex Hormone-Binding Globulin; Single-Blind Method; Testosterone

2006
Equol producer status, salivary estradiol profile and urinary excretion of isoflavones in Irish Caucasian women, following ingestion of soymilk.
    Steroids, 2007, Volume: 72, Issue:1

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Dietary Supplements; Equol; Estradiol; Female; Genistein; Humans; Isoflavones; Middle Aged; Phytoestrogens; Plant Preparations; Saliva; Soy Milk; White People

2007
Monoclonal antibody-based time-resolved fluorescence immunoassays for daidzein, genistein, and equol in blood and urine: application to the Isoheart intervention study.
    Clinical chemistry, 2007, Volume: 53, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Biological Availability; Coronary Disease; Dietary Supplements; Equol; Female; Fluoroimmunoassay; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Mice; Mice, Inbred BALB C; Postmenopause; Reproducibility of Results

2007
Individual differences in equol production capability modulate blood pressure in tibolone-treated postmenopausal women: lack of effect of soy supplementation.
    Climacteric : the journal of the International Menopause Society, 2007, Volume: 10, Issue:6

    Topics: Blood Pressure; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Equol; Estrogen Receptor Modulators; Female; Genistein; Humans; Isoflavones; Male; Middle Aged; Norpregnenes; Phytoestrogens; Postmenopause; Soybean Proteins; Treatment Outcome; Women's Health

2007
Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy.
    BMC cancer, 2008, May-11, Volume: 8

    Topics: Adenocarcinoma; Aged; Dietary Supplements; Equol; Genistein; Humans; Isoflavones; Male; Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life; Receptors, Androgen

2008
A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women.
    Age and ageing, 2009, Volume: 38, Issue:1

    Topics: Aged; Aged, 80 and over; Cognition; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Equol; Female; Genistein; Geriatric Assessment; Humans; Isoflavones; Male; Middle Aged; Neuropsychological Tests; Outcome Assessment, Health Care; Pilot Projects

2009
Prostatic soy isoflavone concentrations exceed serum levels after dietary supplementation.
    The Prostate, 2009, May-15, Volume: 69, Issue:7

    Topics: Adenocarcinoma; Dietary Supplements; Double-Blind Method; Equol; Genistein; Glycine max; Humans; Isoflavones; Male; Mass Spectrometry; Prostatic Neoplasms; Statistics, Nonparametric

2009
Dietary seaweed modifies estrogen and phytoestrogen metabolism in healthy postmenopausal women.
    The Journal of nutrition, 2009, Volume: 139, Issue:5

    Topics: Aged; Cross-Over Studies; Diet; Dietary Supplements; Double-Blind Method; Equol; Estradiol; Estrogens; Female; Genistein; Humans; Isoflavones; Middle Aged; Phytoestrogens; Placebos; Postmenopause; Seaweed; Sex Hormone-Binding Globulin; Soybean Proteins

2009
Effects of a high dose, aglycone-rich soy extract on prostate-specific antigen and serum isoflavone concentrations in men with localized prostate cancer.
    Nutrition and cancer, 2010, Volume: 62, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Dietary Supplements; Double-Blind Method; Equol; Genistein; Glycine max; Humans; Isoflavones; Male; Middle Aged; Phytotherapy; Plant Extracts; Polysaccharides; Prostate-Specific Antigen; Prostatic Neoplasms; Severity of Illness Index; Time Factors

2010
Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk.
    International journal of food sciences and nutrition, 2011, Volume: 62, Issue:6

    Topics: Aged; Animals; Biological Availability; Biomarkers; Diet; Equol; Female; Genistein; Humans; Isoflavones; Malaysia; Middle Aged; Milk; Postmenopause; Soy Foods

2011
Large inter-individual variation in isoflavone plasma concentration limits use of isoflavone intake data for risk assessment.
    European journal of clinical nutrition, 2014, Volume: 68, Issue:10

    Topics: Aged; Asian People; Cross-Over Studies; Dietary Supplements; Equol; Female; Genistein; Humans; Isoflavones; Middle Aged; Postmenopause; Risk Assessment; Soy Foods

2014
Isoflavone supplement composition and equol producer status affect gene expression in adipose tissue: a double-blind, randomized, placebo-controlled crossover trial in postmenopausal women.
    The American journal of clinical nutrition, 2014, Volume: 100, Issue:5

    Topics: Adipose Tissue; Adiposity; Aged; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Equol; Female; Gene Expression; Genistein; Humans; Isoflavones; Middle Aged; Netherlands; Nutritional Status; Postmenopause; Surveys and Questionnaires

2014
Impact of equol-producing capacity and soy-isoflavone profiles of supplements on bone calcium retention in postmenopausal women: a randomized crossover trial.
    The American journal of clinical nutrition, 2015, Volume: 102, Issue:3

    Topics: Administration, Oral; Aged; Bone and Bones; Calcium; Cross-Over Studies; Dietary Supplements; Dose-Response Relationship, Drug; Equol; Female; Genistein; Glycine max; Humans; Isoflavones; Middle Aged; Osteoporosis, Postmenopausal; Phytoestrogens; Postmenopause; Risedronic Acid

2015
Safety and feasibility of estrogen receptor-β targeted phytoSERM formulation for menopausal symptoms: phase 1b/2a randomized clinical trial.
    Menopause (New York, N.Y.), 2019, Volume: 26, Issue:8

    Topics: Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Equol; Estrogen Receptor beta; Female; Genistein; Hot Flashes; Humans; Isoflavones; Middle Aged; Perimenopause

2019
Retrospective analysis of phytoSERM for management of menopause-associated vasomotor symptoms and cognitive decline: a pilot study on pharmacogenomic effects of mitochondrial haplogroup and APOE genotype on therapeutic efficacy.
    Menopause (New York, N.Y.), 2020, Volume: 27, Issue:1

    Topics: Apolipoproteins E; Cognition; Cognitive Dysfunction; Double-Blind Method; Equol; Feasibility Studies; Female; Genistein; Haplotypes; Hot Flashes; Humans; Isoflavones; Menopause; Middle Aged; Mitochondria; Phytoestrogens; Pilot Projects; Retrospective Studies; Selective Estrogen Receptor Modulators; Treatment Outcome

2020

Other Studies

158 other study(ies) available for equol and genistein

ArticleYear
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005
Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein.
    Clinica chimica acta; international journal of clinical chemistry, 1991, Jul-15, Volume: 199, Issue:3

    Topics: 4-Butyrolactone; Butylene Glycols; Chromans; Equol; Female; Furans; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Indicator Dilution Techniques; Isoflavones; Lignans; Lignin; Magnetic Resonance Spectroscopy; Male

1991
The estrogenic activity of certain phytoestrogens in the Siberian sturgeon Acipenser baeri.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:3

    Topics: Animals; Chromans; Chromatography, Thin Layer; Coumestrol; Equol; Estrogens; Estrogens, Non-Steroidal; Fishes; Gas Chromatography-Mass Spectrometry; Genistein; Isoflavones; Liver; Magnetic Resonance Spectroscopy; Phytoestrogens; Plant Preparations; Spectrophotometry, Infrared; Vitellogenins

1991
Identification of phytoestrogens in the urine of male dogs.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:6

    Topics: Animal Feed; Animals; Binding, Competitive; Chromans; Chromatography, High Pressure Liquid; Dogs; Equol; Estrogens; Estrogens, Non-Steroidal; Gas Chromatography-Mass Spectrometry; Genistein; Isoflavones; Male; Phytoestrogens; Plant Preparations; Prostatic Hyperplasia; Receptors, Estrogen; Reference Values

1988
Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids.
    The Journal of endocrinology, 1995, Volume: 147, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Chromans; Depression, Chemical; Equol; Fibroblasts; Genistein; Humans; Isoflavones; Lignans; Male; Prostate; Prostatic Hyperplasia; Skin; Testis

1995
Plasma concentrations of phyto-oestrogens in Japanese men.
    Lancet (London, England), 1993, Nov-13, Volume: 342, Issue:8881

    Topics: Chromans; Diet; Equol; Estrogens, Non-Steroidal; Finland; Genistein; Humans; Isoflavones; Japan; Male; Middle Aged; Prostatic Neoplasms; Risk Factors

1993
Determination of lignans and isoflavonoids in human female plasma following dietary supplementation.
    The Journal of endocrinology, 1994, Volume: 142, Issue:2

    Topics: 4-Butyrolactone; Australia; Chromans; Diet; Equol; Estrogens; Female; Food, Fortified; Gas Chromatography-Mass Spectrometry; Genistein; Glycine max; Humans; Isoflavones; Lignans; Linseed Oil; Middle Aged; Monoamine Oxidase Inhibitors; Neoplasms; Plants, Edible; Postmenopause

1994
Metabolites of dietary (soya) isoflavones in human urine.
    Clinica chimica acta; international journal of clinical chemistry, 1993, Dec-31, Volume: 223, Issue:1-2

    Topics: Adult; Chromans; Chromatography, Gas; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Middle Aged

1993
In vitro bioassays of non-steroidal phytoestrogens.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:5

    Topics: Adenocarcinoma; Alkaline Phosphatase; Biological Assay; Chromans; Coumestrol; Dinoprost; Endometrial Neoplasms; Endometrium; Equol; Estradiol; Female; Genistein; Humans; Isoflavones; Polyunsaturated Alkamides; Tamoxifen; Tumor Cells, Cultured

1993
Regulation of sex hormone-binding globulin production by isoflavonoids and patterns of isoflavonoid conjugation in HepG2 cell cultures.
    Steroids, 1995, Volume: 60, Issue:9

    Topics: Carcinoma, Hepatocellular; Chromans; Equol; Estradiol; Estrogens, Non-Steroidal; Gene Expression Regulation, Neoplastic; Genistein; Humans; Isoflavones; Methylation; RNA, Messenger; Sex Hormone-Binding Globulin; Transcription, Genetic; Tumor Cells, Cultured

1995
Altered time course of urinary daidzein and genistein excretion during chronic soya diet in healthy male subjects.
    Nutrition and cancer, 1995, Volume: 24, Issue:3

    Topics: Absorption; Adult; Chromans; Equol; Estrogens, Non-Steroidal; Genistein; Glycine max; Humans; Isoflavones; Kinetics; Male; Phytoestrogens; Plant Preparations

1995
Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro.
    Nutrition and cancer, 1997, Volume: 27, Issue:1

    Topics: Anticarcinogenic Agents; Breast; Breast Neoplasms; Cell Division; Chromans; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Equol; Estradiol; Estrogen Antagonists; Estrogens, Non-Steroidal; Female; Flavonoids; Genistein; Humans; Isoflavones; Kaempferols; Phytoestrogens; Plant Preparations; Protein Binding; Quercetin; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1997
The isoflavones equol and genistein do not induce xenobiotic-metabolizing enzymes in mouse and in human cells.
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:6

    Topics: Animals; Anticarcinogenic Agents; beta-Naphthoflavone; Chromans; Cytochromes; Enzyme Induction; Enzyme Inhibitors; Equol; Genistein; Glutathione Transferase; Humans; Injections, Intraperitoneal; Isoflavones; Male; Mice; Mice, Inbred BALB C; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Xenobiotics

1997
Plasma and urinary kinetics of the isoflavones daidzein and genistein after a single soy meal in humans.
    The American journal of clinical nutrition, 1998, Volume: 67, Issue:5

    Topics: Adult; Antineoplastic Agents; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Flour; Genistein; Humans; Isoflavones; Male; Middle Aged; Monoamine Oxidase Inhibitors; Postprandial Period; Soybean Proteins; Time Factors

1998
Inhibition of mouse and human CYP 1A- and 2E1-dependent substrate metabolism by the isoflavonoids genistein and equol.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:5

    Topics: Animals; Cell Line, Transformed; Chromans; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Equol; Genistein; Humans; Isoflavones; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Monoamine Oxidase Inhibitors; Nitrophenols; Oxazines; Rats; Rats, Wistar; Substrate Specificity

1998
Phytoestrogens have agonistic and combinatorial effects on estrogen-responsive gene expression in MCF-7 human breast cancer cells.
    Endocrine, 1998, Volume: 8, Issue:2

    Topics: Breast Neoplasms; Chromans; Drug Interactions; Equol; Estrogens; Estrogens, Non-Steroidal; Gene Expression; Genistein; Humans; Isoflavones; Luciferases; Phytoestrogens; Plant Preparations; Transfection; Tumor Cells, Cultured

1998
Assessment of isoflavonoid concentrations in Australian bovine milk samples.
    The Journal of dairy research, 1998, Volume: 65, Issue:3

    Topics: Animals; Australia; Cattle; Chromans; Chromatography, High Pressure Liquid; Equol; Female; Flavonoids; Genistein; Hot Temperature; Isoflavones; Milk; Seasons

1998
Reliability of serum measurements of lignans and isoflavonoid phytoestrogens over a two-year period.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:10

    Topics: 4-Butyrolactone; Adult; Age Factors; Aged; Bias; Breast Neoplasms; Chromans; Equol; Feasibility Studies; Female; Genistein; Humans; Isoflavones; Lignans; Middle Aged; New York City; Pilot Projects; Postmenopause; Premenopause; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Time Factors

1998
Phyto-oestrogen excretion and rate of bone loss in postmenopausal women.
    European journal of clinical nutrition, 1998, Volume: 52, Issue:11

    Topics: 4-Butyrolactone; Aging; Bone Density; Chromans; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Linear Models; Middle Aged; Osteoporosis, Postmenopausal; Phytoestrogens; Plant Preparations; Postmenopause; Prospective Studies; Time Factors

1998
Soy isoflavonoids exhibit in vitro biological activities of loop diuretics.
    The American journal of clinical nutrition, 1998, Volume: 68, Issue:6 Suppl

    Topics: Animals; Chromans; Diuresis; Diuretics; Enzyme Inhibitors; Equol; Furosemide; Genistein; Glomerular Filtration Rate; Hemodynamics; Ion Transport; Isoflavones; Kidney; Monoamine Oxidase Inhibitors; Natriuresis; Rats; Soybean Proteins

1998
Daidzein conjugates are more bioavailable than genistein conjugates in rats.
    The American journal of clinical nutrition, 1998, Volume: 68, Issue:6 Suppl

    Topics: Administration, Oral; Animals; Biological Availability; Chromans; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Equol; Estrogens, Non-Steroidal; Genistein; Isoflavones; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Soybean Proteins

1998
Phytoestrogens inhibit growth and MAP kinase activity in human aortic smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Adult; Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Division; Cell Movement; Cells, Cultured; Chromans; Culture Media; DNA; Dose-Response Relationship, Drug; Equol; Estrogens, Non-Steroidal; Female; Genistein; Humans; Isoflavones; Kinetics; Male; Muscle, Smooth, Vascular; Phytoestrogens; Plant Preparations; Protein Biosynthesis

1999
Urinary excretion of isoflavonoids and the risk of breast cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:1

    Topics: Adult; Anticarcinogenic Agents; Breast Neoplasms; Case-Control Studies; China; Chromans; Confidence Intervals; Creatinine; Equol; Estradiol; Estrogens, Non-Steroidal; Feeding Behavior; Female; Genistein; Glycine max; Humans; Isoflavones; Middle Aged; Monoamine Oxidase Inhibitors; Odds Ratio; Phenols; Risk Factors

1999
The effects of flavonoids on human phenolsulphotransferases: potential in drug metabolism and chemoprevention.
    Life sciences, 1999, Volume: 65, Issue:16

    Topics: Anticarcinogenic Agents; Arylsulfotransferase; Chromans; Enzyme Inhibitors; Equol; Estrogen Receptor Modulators; Flavonoids; Genistein; Humans; Isoenzymes; Isoflavones; Kinetics; Sulfotransferases

1999
Modulation of liposomal membrane fluidity by flavonoids and isoflavonoids.
    Archives of biochemistry and biophysics, 2000, Jan-01, Volume: 373, Issue:1

    Topics: Chromans; Equol; Flavanones; Flavonoids; Fluorescence Polarization; Fluorescent Dyes; Genistein; In Vitro Techniques; Isoflavones; Liposomes; Membrane Fluidity; Palmitic Acids; Rutin; Stearic Acids

2000
Comparison of isoflavones among dietary intake, plasma concentration and urinary excretion for accurate estimation of phytoestrogen intake.
    Journal of epidemiology, 2000, Volume: 10, Issue:2

    Topics: Adult; Aged; Anticarcinogenic Agents; Biomarkers; Chromans; Diet; Diet Records; Energy Intake; Equol; Estrogens, Non-Steroidal; Female; Genistein; Glycine max; Humans; Isoflavones; Middle Aged; Monoamine Oxidase Inhibitors; Phytoestrogens; Plant Preparations; Plants; Regression Analysis

2000
Isoflavone aglycone-rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits.
    The Journal of nutrition, 2000, Volume: 130, Issue:8

    Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Chromans; Copper; Disease Models, Animal; Energy Intake; Equol; Fermentation; Genistein; Glycine max; Isoflavones; Lipids; Lipoproteins, LDL; Male; Malondialdehyde; Phenols; Rabbits; Saponins; Soybean Proteins

2000
Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2000, Volume: 38, Issue:7

    Topics: Animals; Animals, Newborn; Apigenin; Cell Nucleus; Chromans; Chromatography, High Pressure Liquid; Cytosol; Equol; Estrogen Receptor alpha; Female; Flavonoids; Genistein; Isoflavones; Kaempferols; Mice; Mice, Inbred Strains; Organ Size; Quercetin; Receptors, Estrogen; Uterus

2000
Synergistic inhibition of LDL oxidation by phytoestrogens and ascorbic acid.
    Free radical biology & medicine, 2000, Jul-01, Volume: 29, Issue:1

    Topics: Adult; Antioxidants; Ascorbic Acid; Chromans; Drug Synergism; Equol; Estrogens, Non-Steroidal; Female; Genistein; Humans; Isoflavones; Kinetics; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Male; Oxidation-Reduction; Phytoestrogens; Plant Preparations

2000
Effect of phytoestrogen and antioxidant supplementation on oxidative DNA damage assessed using the comet assay.
    Mutation research, 2001, Mar-07, Volume: 485, Issue:2

    Topics: Adult; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Chromans; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Equol; Estradiol; Estrogens, Non-Steroidal; Female; Genistein; Humans; Hydrogen Peroxide; Isoflavones; Lymphocytes; Oxidants; Phytoestrogens; Plant Preparations; Tamoxifen; Vitamin E

2001
Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones.
    Laboratory investigation; a journal of technical methods and pathology, 2001, Volume: 81, Issue:5

    Topics: Age Factors; Animal Feed; Animals; Animals, Newborn; Animals, Suckling; Chromans; Chromatography, High Pressure Liquid; Equol; Estrogens, Non-Steroidal; Female; Genistein; Hormones; Isoflavones; Mice; Models, Animal; Phytoestrogens; Plant Preparations; Rats

2001
Effects of phytoestrogens on growth and DNA integrity in human prostate tumor cell lines: PC-3 and LNCaP.
    Nutrition and cancer, 2000, Volume: 38, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Cell Division; Cell Transformation, Neoplastic; Chromans; Coumestrol; DNA Damage; Equol; Estrogens, Non-Steroidal; Genistein; Humans; Isoflavones; Male; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; Tumor Cells, Cultured

2000
Regulation of phenobarbital-mediated induction of CYP102 (cytochrome P450(BM-3)) in Bacillus megaterium by phytochemicals from soy and green tea.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:10

    Topics: Bacillus megaterium; Bacterial Proteins; Catechin; Chromans; Coumestrol; Cytochrome P-450 Enzyme System; Equol; Genistein; Glycine max; Isoflavones; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Tea; Zearalenone

2001
Effects of phytoestrogens on DNA synthesis and creatine kinase activity in vascular cells.
    American journal of hypertension, 2001, Volume: 14, Issue:12

    Topics: Animals; Aorta; Cells, Cultured; Chromans; Creatine Kinase; Creatine Kinase, MB Form; DNA; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Equol; Estrogen Antagonists; Estrogens, Non-Steroidal; Female; Genistein; Humans; Isoenzymes; Isoflavones; Muscle, Smooth, Vascular; Phytoestrogens; Plant Preparations; Quercetin; Raloxifene Hydrochloride; Rats; Rats, Wistar; Thymidine; Tritium; Umbilical Arteries

2001
Phytoestrogens: dietary intake and excretion in postmenopausal Chinese women.
    Climacteric : the journal of the International Menopause Society, 1998, Volume: 1, Issue:4

    Topics: Adult; Animals; China; Chromans; Diet; Diet Records; Equol; Estrogens, Non-Steroidal; Fabaceae; Female; Genistein; Glycine max; Humans; Isoflavones; Middle Aged; Milk; Phytoestrogens; Plant Preparations; Postmenopause; Vegetables

1998
A combination of dietary fructooligosaccharides and isoflavone conjugates increases femoral bone mineral density and equol production in ovariectomized mice.
    The Journal of nutrition, 2002, Volume: 132, Issue:7

    Topics: Absorptiometry, Photon; Animals; beta-Glucosidase; Bone Density; Calcium; Cecum; Chromans; Diet; Drug Synergism; Equol; Estrogens, Non-Steroidal; Female; Femur; Genistein; Isoflavones; Magnesium; Mice; Oligosaccharides; Osmolar Concentration; Ovariectomy; Phosphorus; Tomography, X-Ray Computed

2002
Phytoestrogen concentrations in serum from Japanese men and women over forty years of age.
    The Journal of nutrition, 2002, Volume: 132, Issue:10

    Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Male; Middle Aged; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; United Kingdom

2002
Soy isoflavonoid equol modulates the growth of benign and malignant prostatic epithelial cells in vitro.
    The Prostate, 2003, Jan-01, Volume: 54, Issue:1

    Topics: Apoptosis; Cell Cycle; Cell Division; Chromans; Diet; Enzyme Inhibitors; Equol; Estrogens, Non-Steroidal; Flow Cytometry; Genistein; Humans; Isoflavones; Male; Plant Proteins; Polysaccharides; Prostate; Prostatic Neoplasms; Soy Foods; Tumor Cells, Cultured

2003
Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3

    Topics: Animals; Calcium; Calcium Channels; Chromans; Drug Interactions; Equol; Estradiol; Fulvestrant; Genistein; Glycine max; Guinea Pigs; Heart Ventricles; Isoflavones; Membrane Potentials; Myocytes, Cardiac

2003
Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry.
    Analytical biochemistry, 2003, Apr-01, Volume: 315, Issue:1

    Topics: 4-Butyrolactone; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Molecular Structure; Phytoestrogens; Plant Preparations; Reproducibility of Results; Sensitivity and Specificity

2003
The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: an antioxidant mechanism for cell-mediated LDL modification.
    Free radical biology & medicine, 2003, May-15, Volume: 34, Issue:10

    Topics: Animals; Antioxidants; Biological Availability; Cells, Cultured; Chromans; Copper; Equol; Estrogens, Non-Steroidal; Genistein; Iron; Isoflavones; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Mice; Monocytes; NADPH Oxidases; Nitric Oxide; Oxidation-Reduction; Phytoestrogens; Plant Preparations; Superoxides; Time Factors

2003
Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:12

    Topics: 4-Butyrolactone; Animals; Cattle; Chromans; Chromatography, Liquid; Coumestrol; Equol; Estrogens, Non-Steroidal; Genistein; Ions; Isoflavones; Lignans; Milk; Molecular Structure; Phytoestrogens; Plant Preparations; Spectrometry, Mass, Electrospray Ionization

2003
Effects of the isoflavones genistein and equol on the gonadal development of Japanese medaka Oryzias latipes.
    Environmental health perspectives, 2003, Volume: 111, Issue:9

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equol; Estrogens, Non-Steroidal; Female; Genistein; Gonads; Hermaphroditic Organisms; Isoflavones; Male; Oryzias; Sex Determination Processes

2003
THE CONVERSION OF GENISTEIN TO EQUOL IN THE FOWL.
    Biochimica et biophysica acta, 1964, Apr-04, Volume: 86

    Topics: Animals; Azo Compounds; Body Fluids; Borates; Chromatography; Equol; Flavones; Genistein; Metabolism; Pectoralis Muscles; Poultry; Pyrans; Research; Tritium; Urine

1964
Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta.
    Bioorganic & medicinal chemistry, 2004, Mar-15, Volume: 12, Issue:6

    Topics: Antineoplastic Agents; Binding Sites; Carcinoma, Endometrioid; Chromatography, High Pressure Liquid; Equol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Female; Genistein; Glycine max; Humans; Isoflavones; Phytoestrogens; Phytotherapy; Plant Preparations; Receptors, Estrogen; Tumor Cells, Cultured

2004
Influence of soya-based infant formula consumption on isoflavone and gut microflora metabolite concentrations in urine and on faecal microflora composition and metabolic activity in infants and children.
    The British journal of nutrition, 2004, Volume: 91, Issue:4

    Topics: Aging; Animals; Bacteria; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Equol; Feces; Genistein; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Isoflavones; Milk; Soy Milk

2004
Isoflavones stimulate estrogen receptor-mediated core histone acetylation.
    Biochemical and biophysical research communications, 2004, Apr-23, Volume: 317, Issue:1

    Topics: Acetylation; Acetyltransferases; Animals; Cell Line; Drosophila; Equol; Estradiol; Estrogen Antagonists; Fulvestrant; Genistein; Histone Acetyltransferases; Histones; Isoflavones; Nuclear Proteins; Nuclear Receptor Coactivator 2; Receptors, Estrogen; Recombinant Proteins; Spodoptera; Tamoxifen; Trans-Activators; Transcription Factors; Transcription, Genetic

2004
Comparisons of percent equol producers between prostate cancer patients and controls: case-controlled studies of isoflavones in Japanese, Korean and American residents.
    Japanese journal of clinical oncology, 2004, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Diet; Equol; Genistein; Humans; Incidence; Isoflavones; Japan; Korea; Male; Middle Aged; Prostatic Neoplasms; United States

2004
Genotoxicity of the isoflavones genistein, daidzein and equol in V79 cells.
    Toxicology letters, 2004, Jun-15, Volume: 151, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzothiazoles; Coloring Agents; Comet Assay; Cricetinae; Cricetulus; DNA Damage; Dose-Response Relationship, Drug; Equol; Fibroblasts; Formazans; Genistein; Isoflavones; Micronucleus Tests; Neutral Red; Sulfonic Acids; Tetrazolium Salts

2004
Synthesis of phytoestrogenic isoflavonoid disulfates.
    Steroids, 2004, Volume: 69, Issue:10

    Topics: Equol; Genistein; Isoflavones; Magnetic Resonance Spectroscopy; Phytoestrogens; Steryl-Sulfatase; Sulfuric Acid Esters

2004
Measurement of isoflavones using liquid chromatography with multi-channel coulometric electrochemical detection.
    BioFactors (Oxford, England), 2004, Volume: 22, Issue:1-4

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Equol; Genistein; Indicators and Reagents; Isoflavones; Spectrophotometry

2004
Absorption of isoflavones in humans: effects of food matrix and processing.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:4

    Topics: Absorption; Beverages; Biological Availability; Digestion; Equol; Food; Food Analysis; Food Handling; Genistein; Humans; Isoflavones; Middle Aged

2006
Sensitive high-performance liquid chromatographic method using coulometric electrode array detection for measurement of phytoestrogens in dried blood spots.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Nov-05, Volume: 826, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Electrochemistry; Electrodes; Equol; Female; Genistein; Humans; Isoflavones; Japan; Perimenopause; Phytoestrogens; Temperature

2005
Short-term phytoestrogen supplementation alters insulin-like growth factor profile but not lipid or antioxidant status.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:3

    Topics: Adult; Antioxidants; Diet; DNA Damage; Equol; Female; Flax; Genistein; Glycine max; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Isoflavones; Kinetics; Lignans; Lipids; Middle Aged; Phytoestrogens

2006
Phyto-oestrogen intake in Scottish men: use of serum to validate a self-administered food-frequency questionnaire in older men.
    European journal of clinical nutrition, 2006, Volume: 60, Issue:1

    Topics: Aged; Biomarkers; Cross-Sectional Studies; Diet Surveys; Equol; Genistein; Glycine max; Humans; Isoflavones; Male; Middle Aged; Phytoestrogens; Reproducibility of Results; Scotland; Surveys and Questionnaires

2006
Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men.
    The Journal of nutrition, 2005, Volume: 135, Issue:11

    Topics: 4-Butyrolactone; Aged; Androgens; Androstane-3,17-diol; Aromatase; Diet; Equol; Genistein; Genotype; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Polymorphism, Genetic; Sex Hormone-Binding Globulin; Testosterone

2005
One-month exposure to soy isoflavones did not induce the ability to produce equol in postmenopausal women.
    European journal of clinical nutrition, 2006, Volume: 60, Issue:9

    Topics: Administration, Oral; Aged; Area Under Curve; Biological Availability; Dietary Supplements; Equol; Female; Genistein; Glycine max; Humans; Isoflavones; Middle Aged; Postmenopause; Time Factors

2006
Dietary modulation of p-nonylphenol-induced polycystic kidneys in male Sprague-Dawley rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 91, Issue:2

    Topics: Acetylglucosaminidase; Animals; Blood Urea Nitrogen; Corn Oil; Creatinine; Diet; Equol; Female; Genistein; Isoflavones; Kidney; Male; Phenols; Polycystic Kidney Diseases; Rats; Rats, Sprague-Dawley; Soybean Oil

2006
Behavioral changes in fish exposed to phytoestrogens.
    Environmental pollution (Barking, Essex : 1987), 2006, Volume: 144, Issue:3

    Topics: Aggression; Animals; Behavior, Animal; Equol; Estradiol; Female; Fishes; Genistein; Isoflavones; Male; Nesting Behavior; Phytoestrogens; Sexual Behavior, Animal; Sitosterols; Swimming; Water Pollutants, Chemical

2006
Antioxidant activity of isoflavones and their major metabolites using different in vitro assays.
    Journal of agricultural and food chemistry, 2006, Apr-19, Volume: 54, Issue:8

    Topics: Antioxidants; Bacteria; Equol; Genistein; Glycine max; Isoflavones; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances

2006
Identification of equol producers in a Japanese population by high-performance liquid chromatography with coulometric array for determining serum isoflavones.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2006, Volume: 13, Issue:5

    Topics: Adult; Chromatography, High Pressure Liquid; Diet; Eating; Equol; Female; Genistein; Humans; Isoflavones; Japan; Male; Middle Aged; Soy Foods; Surveys and Questionnaires

2006
Effects of phytoestrogens on testosterone secretion by Leydig cells from Biłgoraj ganders (Anser anser).
    British poultry science, 2006, Volume: 47, Issue:2

    Topics: Animal Feed; Animals; Dose-Response Relationship, Drug; Equol; Geese; Genistein; Isoflavones; Leydig Cells; Male; Organ Size; Phytoestrogens; Radioimmunoassay; Random Allocation; Reproduction; Seasons; Testosterone

2006
Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: a comparison study using DNA microarray.
    Molecular carcinogenesis, 2006, Volume: 45, Issue:12

    Topics: Androgens; Cell Cycle; Cell Line, Tumor; Equol; Gene Expression; Gene Expression Profiling; Genistein; Glycine max; Humans; Insulin-Like Growth Factor I; Isoflavones; Male; Neoplasms, Hormone-Dependent; Oligonucleotide Array Sequence Analysis; Phytoestrogens; Prostatic Neoplasms; Receptor, IGF Type 1

2006
Soya isoflavones suppress phorbol 12-myristate 13-acetate-induced COX-2 expression in MCF-7 cells.
    The British journal of nutrition, 2006, Volume: 96, Issue:1

    Topics: Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Equol; Female; Genistein; Glycine max; Humans; Isoflavones; Membrane Proteins; Phytoestrogens; Plant Extracts; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate

2006
Bioavailability of isoflavones after ingestion of soy beverages in healthy adults.
    The Journal of nutrition, 2006, Volume: 136, Issue:9

    Topics: Adult; beta-Glucosidase; Biological Availability; Chromatography, High Pressure Liquid; Equol; Female; Fermentation; Food Handling; Genistein; Humans; Isoflavones; Kinetics; Male; Mass Spectrometry; Middle Aged; Soy Milk

2006
Supplementation of difructose anhydride III enhanced elevation of plasma equol concentrations and lowered plasma total cholesterol in isoflavone-fed rats.
    The British journal of nutrition, 2006, Volume: 96, Issue:3

    Topics: Animals; Body Weight; Cecum; Cholesterol; Diet; Dietary Supplements; Disaccharides; Equol; Feces; Genistein; Isoflavones; Male; Oligosaccharides; Phytoestrogens; Rats; Rats, Wistar

2006
Associations among maternal soy intake, isoflavone levels in urine and blood samples, and maternal and umbilical hormone concentrations (Japan).
    Cancer causes & control : CCC, 2006, Volume: 17, Issue:9

    Topics: Adult; Diet Records; Equol; Estradiol; Estriol; Female; Fetal Blood; Genistein; Gestational Age; Gonadal Steroid Hormones; Humans; Isoflavones; Japan; Pregnancy; Soy Foods; Testosterone

2006
Phytoestrogens regulate transcription and translation of vitamin D receptor in colon cancer cells.
    The Journal of endocrinology, 2006, Volume: 191, Issue:2

    Topics: Adenocarcinoma; Blotting, Western; Calcium; Colonic Neoplasms; Equol; Estradiol; Estrogen Receptor beta; Genistein; HT29 Cells; Humans; Immunoprecipitation; Isoflavones; Phytoestrogens; Promoter Regions, Genetic; Protein Biosynthesis; Receptors, Calcitriol; Reverse Transcriptase Polymerase Chain Reaction; Sp1 Transcription Factor; Transcription Factor AP-1; Transcription, Genetic; Transfection

2006
Phytoestrogen action in Leydig cells of Biłgoraj ganders (Anser anser).
    Reproductive biology, 2006, Volume: 6 Suppl 2

    Topics: Animals; Equol; Geese; Genistein; Isoflavones; Leydig Cells; Male; Phenols; Phytoestrogens; Poland; Protein-Tyrosine Kinases; Radioimmunoassay; Tamoxifen; Testosterone

2006
Modulation of soy isoflavones bioavailability and subsequent effects on bone health in ovariectomized rats: the case for equol.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007, Volume: 18, Issue:5

    Topics: Animals; Biomarkers; Body Weight; Bone Density; Bone Resorption; Disease Models, Animal; Equol; Female; Femur; Genistein; Glycine max; Isoflavones; Organ Size; Osteocalcin; Osteoporosis; Ovariectomy; Phytoestrogens; Rats; Rats, Wistar; Uterus

2007
Phyto-oestrogens and risk of prostate cancer in Scottish men.
    The British journal of nutrition, 2007, Volume: 98, Issue:2

    Topics: 4-Butyrolactone; Aged; Case-Control Studies; Diet; Diet Surveys; Energy Intake; Equol; Genistein; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Prostatic Neoplasms; Risk Assessment; Scotland

2007
Simultaneous determination of daidzein, equol, genistein and bisphenol A in human urine by a fast and simple method using SPE and GC-MS.
    Molecular nutrition & food research, 2007, Volume: 51, Issue:7

    Topics: Adult; Benzhydryl Compounds; Diet; Equol; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Phenols; Phytoestrogens; Reproducibility of Results

2007
The effect of the phytoestrogens genistein, daidzein, and equol on the growth of tamoxifen-resistant T47D/PKC alpha.
    Nutrition and cancer, 2007, Volume: 58, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Interactions; Equol; Female; Genistein; Glycine max; Humans; Isoflavones; Mice; Mice, Nude; Random Allocation; Safety; Tamoxifen

2007
Isoflavonoid-based bone-sparing treatments exert a low activity on reproductive organs and on hepatic metabolism of estradiol in ovariectomized rats.
    Toxicology and applied pharmacology, 2007, Oct-15, Volume: 224, Issue:2

    Topics: Animals; Bone Density; Cytochrome P-450 Enzyme System; Disease Models, Animal; Equol; Estradiol; Female; Gene Expression Regulation; Genistein; Isoflavones; Menopause; Microsomes, Liver; Organ Size; Osteoporosis; Ovariectomy; Phytoestrogens; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Uterus; Vagina

2007
Inhibition by soya isoflavones of human polymorphonuclear leukocyte function: possible relevance for the beneficial effects of soya intake.
    The British journal of nutrition, 2008, Volume: 99, Issue:2

    Topics: Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Equol; Focal Adhesion Kinase 2; Genistein; Glycine max; Humans; Isoflavones; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; P-Selectin; Pancreatic Elastase; Phosphorylation; Platelet Adhesiveness; Superoxides

2008
Soy and prostate cancer study results mixed.
    Journal of the National Cancer Institute, 2007, Sep-19, Volume: 99, Issue:18

    Topics: Anticarcinogenic Agents; Equol; Feeding Behavior; Genistein; Humans; Intestines; Isoflavones; Japan; Male; Phytoestrogens; Prostatic Neoplasms; Soy Foods

2007
Role of tyrosine phosphorylation in U46619-induced vasoconstriction of pulmonary vasculature and its modulation by genistein, daidzein, and equol.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blotting, Western; Caffeine; Calcimycin; Cattle; Dose-Response Relationship, Drug; Equol; Genistein; In Vitro Techniques; Isoflavones; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Phytoestrogens; Potassium Chloride; Protein-Tyrosine Kinases; Proteins; Pulmonary Artery; Pulmonary Veins; Tyrosine; Vasoconstriction

2007
Urinary isoflavonoid excretion is similar after consuming soya milk and miso soup in Japanese-American women.
    The British journal of nutrition, 2008, Volume: 100, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Asian; Equol; Female; Fermentation; Genistein; Humans; Isoflavones; Middle Aged; Nutritional Physiological Phenomena; Phytoestrogens; Soy Foods; Soy Milk; Specimen Handling

2008
Topical isoflavones provide effective photoprotection to skin.
    Photodermatology, photoimmunology & photomedicine, 2008, Volume: 24, Issue:2

    Topics: Administration, Cutaneous; Animals; Ascorbic Acid; Coumaric Acids; Dose-Response Relationship, Drug; Drug Combinations; Equol; Genistein; Isoflavones; Phytotherapy; Plants, Medicinal; Skin; Sunburn; Sunlight; Sunscreening Agents; Swine; Vitamin E

2008
Validation of soy protein estimates from a food-frequency questionnaire with repeated 24-h recalls and isoflavonoid excretion in overnight urine in a Western population with a wide range of soy intakes.
    The American journal of clinical nutrition, 2008, Volume: 87, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Equol; Female; Genistein; Humans; Isoflavones; Male; Mental Recall; Middle Aged; Prospective Studies; Soybean Proteins; Statistics, Nonparametric; Surveys and Questionnaires; Time Factors

2008
Effect of sulphation on the oestrogen agonist activity of the phytoestrogens genistein and daidzein in MCF-7 human breast cancer cells.
    The Journal of endocrinology, 2008, Volume: 197, Issue:3

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Equol; Estradiol; Estrogen Receptor alpha; Female; Genistein; Humans; Isoflavones; Phytoestrogens; Recombinant Proteins; Structure-Activity Relationship; Sulfates

2008
Modulation of neurotoxicant-induced increases in intracellular calcium by phytoestrogens differ for amyloid beta peptide (Abeta) and 1-methyl-4-phenyl-pyridine (MPP(+)).
    Journal of applied toxicology : JAT, 2009, Volume: 29, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyloid beta-Peptides; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Survival; Drug Antagonism; Equol; Genistein; Humans; Isoflavones; L-Lactate Dehydrogenase; Neuroblastoma; Neurotoxins; Nifedipine; Phytoestrogens

2009
Concentrations of isoflavones and their metabolites in the blood of pregnant and non-pregnant heifers fed soy bean.
    The Journal of reproduction and development, 2008, Volume: 54, Issue:5

    Topics: Animal Feed; Animals; Cattle; Equol; Female; Genistein; Gestational Age; Glycine max; Isoflavones; Phenols; Pregnancy; Pregnancy, Animal; Time Factors

2008
Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets.
    Thrombosis research, 2009, Volume: 123, Issue:5

    Topics: Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Equol; Fatty Acids, Unsaturated; Genistein; Humans; Hydrazines; Isoflavones; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane A2, Prostaglandin H2

2009
Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 112, Issue:4-5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Contraceptives, Oral; CpG Islands; Cricetinae; Cricetulus; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP3A; Diet; Equol; Female; Gene Expression; Genistein; Isoflavones; Liver; Macaca fascicularis; Mammary Glands, Animal; RNA, Messenger

2008
Respective contribution exerted by AF-1 and AF-2 transactivation functions in estrogen receptor alpha induced transcriptional activity by isoflavones and equol: consequence on breast cancer cell proliferation.
    Molecular nutrition & food research, 2009, Volume: 53, Issue:5

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Equol; Estrogen Receptor alpha; Female; Genistein; Humans; Isoflavones; Phosphorylation; Protein Structure, Tertiary; Transcriptional Activation

2009
Isolation of a human intestinal bacterium capable of daidzein and genistein conversion.
    Applied and environmental microbiology, 2009, Volume: 75, Issue:6

    Topics: Actinobacteria; Aerobiosis; DNA, Bacterial; DNA, Ribosomal; Equol; Feces; Gastrointestinal Tract; Genes, rRNA; Genistein; Humans; Isoflavones; Molecular Sequence Data; Phylogeny; RNA, Bacterial; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid

2009
Ileal and faecal digestibility of daidzein and genistein and plasma bioavailability of these isoflavones and their bioactive metabolites in the ovariectomised rat.
    Molecular nutrition & food research, 2009, Volume: 53 Suppl 1

    Topics: Animals; Bacteria; Biological Availability; Digestion; Disease Models, Animal; Equol; Feces; Female; Genistein; Humans; Ileum; Isoflavones; Osteoporosis, Postmenopausal; Ovariectomy; Phenols; Rats; Rats, Sprague-Dawley

2009
Equol but not genistein improves early metaphyseal fracture healing in osteoporotic rats.
    Planta medica, 2009, Volume: 75, Issue:5

    Topics: Animals; Bony Callus; Disease Models, Animal; Elasticity; Equol; Estradiol; Estrogens; Female; Fracture Healing; Genistein; Glycine max; Isoflavones; Osteoclasts; Osteoporosis; Ovariectomy; Phytoestrogens; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tibia

2009
Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner.
    The Journal of nutrition, 2009, Volume: 139, Issue:5

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Chlorocebus aethiops; Cytochrome P-450 CYP3A; Equol; Gene Expression Regulation; Genistein; Humans; Isoflavones; Kidney; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Knockout; Polymerase Chain Reaction; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Steroid; RNA, Messenger; Species Specificity; Transfection

2009
Delayed activation of extracellular-signal-regulated kinase 1/2 is involved in genistein- and equol-induced cell proliferation and estrogen-receptor-alpha-mediated transcription in MCF-7 breast cancer cells.
    The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:5

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Equol; Estrogen Antagonists; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Female; Genes, Reporter; Genistein; Humans; Isoflavones; Phosphorylation; Phytoestrogens; Protein Processing, Post-Translational; Time Factors; Transcriptional Activation

2010
Effect of glycosidation of isoflavones on their bioavailability and pharmacokinetics in aged male rats.
    Molecular nutrition & food research, 2009, Volume: 53 Suppl 1

    Topics: Aging; Animals; Biological Availability; Diet; Equol; Genistein; Glucosides; Glycine max; Glycosylation; Injections, Intravenous; Isoflavones; Male; Phytoestrogens; Rats; Rats, Inbred F344

2009
Isoflavone supplements stimulated the production of serum equol and decreased the serum dihydrotestosterone levels in healthy male volunteers.
    Prostate cancer and prostatic diseases, 2009, Volume: 12, Issue:3

    Topics: Adult; Cholesterol; Dietary Supplements; Dihydrotestosterone; Equol; Genistein; Humans; Isoflavones; Male; Middle Aged; Prostatic Neoplasms; Sex Hormone-Binding Globulin

2009
Changes in the histomorphometric and biomechanical properties of the proximal femur of ovariectomized rat after treatment with the phytoestrogens genistein and equol.
    Planta medica, 2010, Volume: 76, Issue:3

    Topics: Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Remodeling; Diet; Equol; Estradiol; Estrogens; Female; Femur; Genistein; Glycine max; Isoflavones; Ovariectomy; Phytoestrogens; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley

2010
Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents.
    The Journal of nutrition, 2009, Volume: 139, Issue:12

    Topics: Dietary Supplements; Equol; Estradiol; Feces; Flavanones; Flavonoids; Genistein; Humans; Isoflavones; Lignans; Phytoestrogens

2009
Comparison of urodynamic effects of phytoestrogens equol, puerarin and genistein with these of estradiol 17beta in ovariectomized rats.
    Experimental gerontology, 2010, Volume: 45, Issue:2

    Topics: Aging; Animals; Equol; Estradiol; Female; Genistein; Isoflavones; Ovariectomy; Phytoestrogens; Pressure; Rats; Rats, Sprague-Dawley; Urethra; Urinary Bladder; Urinary Incontinence; Urodynamics

2010
Modulation of monoamine neurotransmitters in fighting fish Betta splendens exposed to waterborne phytoestrogens.
    Fish physiology and biochemistry, 2010, Volume: 36, Issue:4

    Topics: Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Equol; Genistein; Isoflavones; Male; Norepinephrine; Perciformes; Phytoestrogens; Serotonin; Sitosterols; Vesicular Monoamine Transport Proteins; Water Pollutants, Chemical

2010
Effects of isoflavones equol and genistein on bone quality in a rat osteopenia model.
    Phytotherapy research : PTR, 2010, Volume: 24 Suppl 2

    Topics: Animals; Biomechanical Phenomena; Bone and Bones; Bone Diseases, Metabolic; Compressive Strength; Equol; Estradiol; Female; Genistein; Isoflavones; Osteocalcin; Ovariectomy; Phytoestrogens; Rats

2010
Evaluation of bone quality and quantity in osteoporotic mice--the effects of genistein and equol.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:6

    Topics: Animals; Biomechanical Phenomena; Bone Density; Bone Density Conservation Agents; Equol; Estradiol; Female; Genistein; Isoflavones; Mice; Mice, Inbred C57BL; Osteoporosis; Ovariectomy; Phytoestrogens; Phytotherapy; Plant Extracts; Tibia

2010
Effects of genistein and equol on human and rat testicular 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities.
    Asian journal of andrology, 2010, Volume: 12, Issue:4

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Animals; Equol; Genistein; Humans; Isoflavones; Kinetics; Leydig Cells; Male; Microsomes; Rats; Rats, Sprague-Dawley; Testis

2010
Dietary genistein and equol (4', 7 isoflavandiol) reduce oxidative stress and protect rats against focal cerebral ischemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:3

    Topics: Animals; Brain Ischemia; Diet; Equol; Female; Genistein; Isoflavones; Male; Ovariectomy; Oxidative Stress; Phytoestrogens; Rats; Sex Characteristics; Thiobarbituric Acid Reactive Substances; Weight Gain

2010
Mammary gland differentiation by early life exposure to enantiomers of the soy isoflavone metabolite equol.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Body Weight; Carcinogens; Disease Models, Animal; Equol; Female; Genistein; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Size; Phytoestrogens; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors

2010
Urinary phytoestrogens and risk of prostate cancer in Jamaican men.
    Cancer causes & control : CCC, 2010, Volume: 21, Issue:12

    Topics: Aged; Carcinoma; Case-Control Studies; Equol; Genistein; Humans; Isoflavones; Jamaica; Lignans; Male; Middle Aged; Phytoestrogens; Prostatic Neoplasms; Risk

2010
Urinary isoflavone phytoestrogens in German children and adolescents--a longitudinal examination in the DONALD cohort.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:3

    Topics: Adolescent; Biomarkers; Child; Diet; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Germany; Glycine max; Humans; Isoflavones; Linear Models; Longitudinal Studies; Male; Phytoestrogens; White People

2011
Quantification of five isoflavones and coumestrol in various solid agroenvironmental matrices using ¹³c₃-labeled internal standards.
    Journal of agricultural and food chemistry, 2011, Feb-09, Volume: 59, Issue:3

    Topics: Chromatography, High Pressure Liquid; Coumestrol; Equol; Genistein; Isoflavones; Manure; Phytoestrogens; Soil; Tandem Mass Spectrometry; Trifolium

2011
Lactobacillus rhamnosus JCM 2771: impact on metabolism of isoflavonoids in the fecal flora from a male equol producer.
    Current microbiology, 2011, Volume: 62, Issue:5

    Topics: Equol; Feces; Genistein; Humans; Intestinal Mucosa; Intestines; Isoflavones; Lacticaseibacillus rhamnosus; Male; Models, Biological

2011
Dairy consumption is a significant correlate of urinary equol concentration in a representative sample of US adults.
    The American journal of clinical nutrition, 2011, Volume: 93, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Dairy Products; Diet; Equol; Female; Genistein; Humans; Isoflavones; Male; Middle Aged; Nutrition Surveys; Phytoestrogens; Soy Foods; United States; Young Adult

2011
Soy isoflavone equol perpetuates dextran sulfate sodium-induced acute colitis in mice.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:3

    Topics: Animals; Body Weight; Colitis; Dextran Sulfate; Disease Models, Animal; Equol; Female; Genistein; Interleukin-10; Isoflavones; Mice; Mice, Inbred BALB C; T-Lymphocytes

2011
Soy isoflavones augment the effect of TRAIL-mediated apoptotic death in prostate cancer cells.
    Oncology reports, 2011, Volume: 26, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Cytotoxins; Equol; Genistein; Glycine max; Humans; Isoflavones; Male; Membrane Potential, Mitochondrial; Plant Extracts; Prostatic Neoplasms; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand

2011
Distribution of isoflavones in samples of serum, liver and mammary glands of rats or pigs fed dietary isoflavones.
    Annals of nutrition & metabolism, 2011, Volume: 58, Issue:3

    Topics: Animals; Body Weight; Chromatography, Liquid; Diet; Dietary Supplements; Equol; Female; Genistein; Isoflavones; Liver; Male; Mammary Glands, Animal; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Soybean Proteins; Swine

2011
Experimentally induced mastitis and metritis modulate soy bean derived isoflavone biotransformation in diary cows.
    Theriogenology, 2011, Volume: 76, Issue:9

    Topics: Animals; Biotransformation; Cattle; Cattle Diseases; Equol; Female; Genistein; Glucuronidase; Glycine max; Isoflavones; Mastitis, Bovine; Metrial Gland; Phytoestrogens; Uterine Diseases

2011
Daidzein and genistein are converted to equol and 5-hydroxy-equol by human intestinal Slackia isoflavoniconvertens in gnotobiotic rats.
    The Journal of nutrition, 2012, Volume: 142, Issue:1

    Topics: Actinobacteria; Animals; Chromatography, High Pressure Liquid; Colony Count, Microbial; Equol; Female; Genistein; Germ-Free Life; Humans; Insulin-Like Growth Factor I; Intestinal Mucosa; Intestines; Isoflavones; Male; Rats; Real-Time Polymerase Chain Reaction

2012
Effect of 17β-estradiol and flavonoids on the regulation of expression of newly identified oestrogen responsive genes in a rat raphe nuclei-derived cell line.
    Journal of cellular physiology, 2012, Volume: 227, Issue:10

    Topics: Animals; Cell Differentiation; Cell Line; Cell Proliferation; Down-Regulation; Equol; Estradiol; Estrogen Receptor beta; Estrogens; Flavanones; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Genistein; Isoflavones; Phytoestrogens; Rats; RNA, Messenger; SOXF Transcription Factors

2012
Isoflavones suppress the expression of the FcεRI high-affinity immunoglobulin E receptor independent of the estrogen receptor.
    Journal of agricultural and food chemistry, 2012, Aug-29, Volume: 60, Issue:34

    Topics: Animals; Anti-Allergic Agents; Basophils; Cell Line; Equol; Estradiol; Estrogen Antagonists; Fulvestrant; Genistein; Glycine max; Humans; Immunoglobulin E; Isoflavones; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Receptors, Estrogen; Receptors, IgE

2012
Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: a nested case-control study from the Korean Multi-Center Cancer Cohort.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:11

    Topics: 4-Butyrolactone; Aged; Anticarcinogenic Agents; Asian People; Case-Control Studies; CDC2 Protein Kinase; Equol; fas Receptor; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Genistein; Humans; Isoflavones; Lignans; Male; MAP Kinase Kinase Kinase 1; Middle Aged; Odds Ratio; Phytoestrogens; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-akt; Republic of Korea; Signal Transduction; Stomach Neoplasms

2012
Association between precocious puberty and some endocrine disruptors in human plasma.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2013, Volume: 48, Issue:8

    Topics: Benzhydryl Compounds; Case-Control Studies; Child; Diethylhexyl Phthalate; Endocrine Disruptors; Equol; Female; Genistein; Humans; Isoflavones; Male; Phenols; Phthalic Acids; Puberty, Precocious; Reproducibility of Results

2013
Identification and expression of genes involved in the conversion of daidzein and genistein by the equol-forming bacterium Slackia isoflavoniconvertens.
    Applied and environmental microbiology, 2013, Volume: 79, Issue:11

    Topics: Actinobacteria; Base Sequence; Chromatography, Affinity; Chromatography, High Pressure Liquid; Electrophoresis, Gel, Two-Dimensional; Equol; Escherichia coli; Genistein; Humans; Intestines; Isoflavones; Molecular Sequence Data; Oxidoreductases; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology

2013
Estrogen receptor alpha augments changes in hemostatic gene expression in HepG2 cells treated with estradiol and phytoestrogens.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Jan-15, Volume: 21, Issue:2

    Topics: Blood Coagulation; Equol; Estradiol; Estrogen Receptor alpha; Factor VII; Fibrin; Gene Expression; Genistein; Hemostatics; Hep G2 Cells; Hepatocytes; Humans; Isoflavones; Phytoestrogens; Plant Extracts; Plasminogen Activator Inhibitor 1; Prothrombin; RNA, Messenger; Tissue Plasminogen Activator

2014
Comparative study of dietary soy phytoestrogens genistein and equol effects on growth parameters and ovarian development in farmed female beluga sturgeon, Huso huso.
    Fish physiology and biochemistry, 2014, Volume: 40, Issue:1

    Topics: Animals; Aquaculture; Dietary Supplements; Equol; Female; Fishes; Genistein; Gonadal Steroid Hormones; Laparoscopy; Oocytes; Ovary; Phytoestrogens; Random Allocation

2014
In vitro and in vivo effects of phytoestrogens on protein turnover in rainbow trout (Oncorhynchus mykiss) white muscle.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2014, Volume: 165

    Topics: Animals; Cell Proliferation; Cells, Cultured; Equol; Female; Gene Expression; Genistein; Isoflavones; Muscle Cells; Muscle Proteins; Muscles; Oncorhynchus mykiss; Phytoestrogens; Protein Biosynthesis; Proteolysis; Receptors, Estrogen

2014
Transport of steroid hormones, phytoestrogens, and estrogenic activity across a swine lagoon/sprayfield system.
    Environmental science & technology, 2014, Oct-07, Volume: 48, Issue:19

    Topics: Agriculture; Androgens; Androstenedione; Animals; Diet; Environmental Monitoring; Equol; Estrogens; Estrone; Feces; Genistein; Hormones; Isoflavones; Phytoestrogens; Progesterone; Steroids; Swine; Urine

2014
A cross-sectional study of equol producer status and self-reported vasomotor symptoms.
    Menopause (New York, N.Y.), 2015, Volume: 22, Issue:5

    Topics: Cross-Sectional Studies; Diet; Equol; Female; Genistein; Hot Flashes; Humans; Isoflavones; Menopause; Middle Aged; Postmenopause; Self Report; Soy Foods; Surveys and Questionnaires; Sweating

2015
The intracellular metabolism of isoflavones in endothelial cells.
    Food & function, 2015, Volume: 6, Issue:1

    Topics: Biological Transport; Caco-2 Cells; Cardiotonic Agents; Cells, Cultured; Endothelium, Vascular; Enterocytes; Equol; Genistein; Glucuronides; Hep G2 Cells; Hepatocytes; Human Umbilical Vein Endothelial Cells; Humans; Intestinal Absorption; Isoflavones; Kinetics; Methylation; Molecular Structure; Organ Specificity; Sulfuric Acid Esters

2015
Plasma isoflavone concentration is associated with decreased risk of type 2 diabetes in Korean women but not men: results from the Korean Genome and Epidemiology Study.
    Diabetologia, 2015, Volume: 58, Issue:4

    Topics: Asian People; Case-Control Studies; Chi-Square Distribution; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diet; Equol; Female; Genistein; Genome, Human; Humans; Isoflavones; Logistic Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Protective Factors; Republic of Korea; Risk Assessment; Risk Factors; Sex Factors; Soy Foods; Tandem Mass Spectrometry

2015
Urinary phytoestrogens in relation to metabolic disturbances among children and adolescents.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2015, Volume: 50, Issue:2

    Topics: Adolescent; Blood Glucose; Blood Pressure; Body Mass Index; Child; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Dyslipidemias; Equol; Genistein; Glucose; Glucose Intolerance; Humans; Lipid Metabolism; Phytoestrogens; Triglycerides

2015
Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors.
    Clinical & experimental metastasis, 2015, Volume: 32, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Bone Neoplasms; Breast Neoplasms; Cell Proliferation; Diet; Dietary Supplements; Disease Models, Animal; Equol; Female; Genistein; Isoflavones; Ki-67 Antigen; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; Prognosis; Random Allocation; Soy Foods

2015
Enhanced Estrogenic Activity of Soybean Isoflavones by Coadministration of Liuwei Dihuang Pills in Ovariectomized Rats.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:7

    Topics: Animals; beta-Glucosidase; Bifidobacterium; Diet; Drugs, Chinese Herbal; Equol; Female; Genistein; Glycine max; Intestines; Isoflavones; Lactobacillus; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; RNA, Messenger

2015
Red clover isoflavone metabolite bioavailability is decreased after fructooligosaccharide supplementation.
    Fitoterapia, 2015, Volume: 105

    Topics: Adult; Biological Availability; Dietary Supplements; Equol; Female; Genistein; Humans; Isoflavones; Male; Oligosaccharides; Trifolium; Young Adult

2015
Soy isoflavone metabolism in cats compared with other species: urinary metabolite concentrations and glucuronidation by liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:5

    Topics: Animals; Cats; Dogs; Equol; Estradiol; Ferrets; Genistein; Glucuronidase; Glycine max; Herpestidae; Isoflavones; Liver; Microsomes, Liver; Species Specificity

2016
A novel UHPLC method for the rapid and simultaneous determination of daidzein, genistein and equol in human urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Nov-15, Volume: 1005

    Topics: Chromatography, High Pressure Liquid; Dietary Supplements; Equol; Genistein; Glycine max; Humans; Isoflavones; Limit of Detection; Linear Models; Menopause; Plant Extracts; Reproducibility of Results; Solid Phase Extraction

2015
Phytoestrogens Activate the Estrogen Receptor in HepG2 Cells.
    Methods in molecular biology (Clifton, N.J.), 2016, Volume: 1366

    Topics: Carcinoma, Hepatocellular; Equol; Estradiol; Estrogen Receptor alpha; Gene Expression Regulation, Neoplastic; Genistein; Hep G2 Cells; Humans; Isoflavones; Liver Neoplasms; Phytoestrogens; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Taq Polymerase; Transfection; Workflow

2016
Urine phyto-oestrogen metabolites are not significantly associated with risk of type 2 diabetes: the Singapore Chinese health study.
    The British journal of nutrition, 2016, Volume: 115, Issue:9

    Topics: Asian People; Case-Control Studies; Diabetes Mellitus, Type 2; Equol; Female; Genistein; Humans; Isoflavones; Lignans; Logistic Models; Male; Middle Aged; Odds Ratio; Phytoestrogens; Risk Factors; Singapore

2016
Plasma isoflavones in Malaysian men according to vegetarianism and by age.
    Asia Pacific journal of clinical nutrition, 2016, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Cross-Sectional Studies; Dairy Products; Diet, Vegetarian; Eggs; Equol; Estradiol; Estrone; Genistein; Humans; Isoflavones; Malaysia; Male; Middle Aged; Phytoestrogens; Testosterone

2016
A combination of soy isoflavones and cello-oligosaccharides changes equol/O-desmethylangolensin production ratio and attenuates bone fragility in ovariectomized mice.
    Bioscience, biotechnology, and biochemistry, 2016, Volume: 80, Issue:8

    Topics: Absorptiometry, Photon; Animals; Bone Density; Cellobiose; Equol; Female; Femur; Food, Formulated; Fractures, Bone; Genistein; Glycine max; Isoflavones; Mice; Ovariectomy

2016
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells.
    Food chemistry, 2016, Nov-01, Volume: 210

    Topics: Animals; Caco-2 Cells; Cattle; Epithelial Cells; Equol; Gene Expression; Genistein; Glycine max; Humans; Inflammation; Isoflavones; Lipopolysaccharides; Milk; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Signal Transduction

2016
Urine and serum biomonitoring of exposure to environmental estrogens II: Soy isoflavones and zearalenone in pregnant women.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 95

    Topics: Adult; Cohort Studies; Diet; Environmental Exposure; Environmental Monitoring; Equol; Estrogens; Female; Genistein; Glycine max; Humans; Isoflavones; Phytoestrogens; Pregnancy; Tandem Mass Spectrometry; Zearalenone

2016
Relationship of equol production between children aged 5-7 years and their mothers.
    European journal of nutrition, 2017, Volume: 56, Issue:5

    Topics: Adult; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Diet; Diet Records; Equol; Female; Follow-Up Studies; Genistein; Humans; Isoflavones; Japan; Life Style; Limit of Detection; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Middle Aged; Mothers; Snacks; Surveys and Questionnaires

2017
Relationship of serum levels and dietary intake of isoflavone, and the novel bacterium Slackia sp. strain NATTS with the risk of prostate cancer: a case-control study among Japanese men.
    International urology and nephrology, 2016, Volume: 48, Issue:9

    Topics: Actinobacteria; Aged; Case-Control Studies; Diet; Equol; Feces; Genistein; Humans; Isoflavones; Japan; Male; Middle Aged; Odds Ratio; Prostatic Neoplasms; Surveys and Questionnaires

2016
Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity.
    BMC pharmacology & toxicology, 2017, 09-06, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Equol; Estradiol; Estrogens; Genistein; Glycine max; Humans; Isoflavones; Lomustine; Medulloblastoma; Neuroectodermal Tumors, Primitive; Vincristine

2017
Pharmacokinetics and safety profile of single-dose administration of an estrogen receptor β-selective phytoestrogenic (phytoSERM) formulation in perimenopausal and postmenopausal women.
    Menopause (New York, N.Y.), 2018, Volume: 25, Issue:2

    Topics: Area Under Curve; Drug Combinations; Equol; Estrogen Receptor beta; Female; Genistein; Humans; Isoflavones; Middle Aged; Phytoestrogens; Selective Estrogen Receptor Modulators

2018
Biosynthesis of (-)-5-Hydroxy-equol and 5-Hydroxy-dehydroequol from Soy Isoflavone, Genistein Using Microbial Whole Cell Bioconversion.
    ACS chemical biology, 2017, 11-17, Volume: 12, Issue:11

    Topics: Actinobacteria; Biosynthetic Pathways; Biotransformation; Equol; Escherichia coli; Gene Expression; Genistein; Isoflavones; Oxidoreductases; Phytoestrogens; Racemases and Epimerases; Recombinant Proteins

2017
Comparison of flavonoids and isoflavonoids to inhibit rat and human 11β-hydroxysteroid dehydrogenase 1 and 2.
    Steroids, 2018, Volume: 132

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Apigenin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equol; Flavonoids; Genistein; Humans; Isoflavones; Molecular Docking Simulation; Protein Conformation; Quercetin; Rats

2018
Daidzein reductase of Eggerthella sp. YY7918, its octameric subunit structure containing FMN/FAD/4Fe-4S, and its enantioselective production of R-dihydroisoflavones.
    Journal of bioscience and bioengineering, 2018, Volume: 126, Issue:3

    Topics: Actinobacteria; Coenzymes; Equol; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Genistein; Humans; Iron; Isoflavones; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Protein Multimerization; Protein Structure, Quaternary; Protein Subunits; Stereoisomerism; Sulfur

2018
Employing different types of phytoestrogens improve bone mineralization in bisphenol A stimulated osteoblast.
    Life sciences, 2018, Oct-01, Volume: 210

    Topics: Benzhydryl Compounds; Calcification, Physiologic; Cell Differentiation; Cells, Cultured; Equol; Estrogens, Non-Steroidal; Genistein; Humans; Isoflavones; Osteoblasts; Osteogenesis; Phenols; Phytoestrogens

2018
Lack of combination effects of soy isoflavones and taxane chemotherapy of castration-resistant prostate cancer.
    The Prostate, 2019, Volume: 79, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Growth Processes; Cell Line, Tumor; Dietary Supplements; Docetaxel; Drug Synergism; Equol; Food-Drug Interactions; Genistein; Glycine max; Isoflavones; Male; Mice; Mice, Nude; Prostatic Neoplasms, Castration-Resistant; Random Allocation; Taxoids; Xenograft Model Antitumor Assays

2019
Screening dietary biochanin A, daidzein, equol and genistein for their potential to increase DHA biosynthesis in rainbow trout (Oncorhynchus mykiss).
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Animal Feed; Animals; Biosynthetic Pathways; Dietary Supplements; Docosahexaenoic Acids; Equol; Female; Fisheries; Genistein; Isoflavones; Lipid Metabolism; Liver; Oncorhynchus mykiss; Plant Oils

2019
Urinary equol, but not daidzein and genistein, was inversely associated with the risk of type 2 diabetes in Chinese adults.
    European journal of nutrition, 2020, Volume: 59, Issue:2

    Topics: Biomarkers; China; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Incidence; Isoflavones; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Risk Assessment

2020
(±)-Equol does not interact with genistein on estrogen-dependent breast tumor growth.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 136

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Equol; Female; Genistein; Humans; Mammary Glands, Animal; Mice, Inbred BALB C; Mice, Nude; Phytoestrogens

2020
Equol Inhibits Mushroom Tyrosinase in Vitro through Tight Binding.
    Biological & pharmaceutical bulletin, 2020, Volume: 43, Issue:3

    Topics: Agaricales; Equol; Genistein; Monophenol Monooxygenase; Pyrones

2020
Genistein Suppresses v-Src-Driven Proliferative Activity by Arresting the Cell-Cycle at G2/M through Increasing p21 Level in Src-Activated Human Gallbladder Carcinoma cells.
    Nutrition and cancer, 2021, Volume: 73, Issue:8

    Topics: Apoptosis; Cell Cycle; Equol; Gallbladder Neoplasms; Genistein; Humans; Isoflavones

2021
The Connection between Urinary Equol Levels and the Prevalence of Atopic Dermatitis.
    International archives of allergy and immunology, 2021, Volume: 182, Issue:1

    Topics: Age Factors; Biomarkers; Case-Control Studies; Child; Cross-Sectional Studies; Dermatitis, Atopic; Disease Susceptibility; Equol; Female; Genistein; Glycine max; Humans; Isoflavones; Male; Prevalence; Severity of Illness Index

2021
Strategies to achieve significant physiological concentrations of bioactive phytoestrogens in plasma.
    Critical reviews in food science and nutrition, 2023, Volume: 63, Issue:14

    Topics: Equol; Genistein; Intestines; Phytoestrogens

2023
Essential Elements and Isoflavonoids in the Prevention of Prostate Cancer.
    Nutrients, 2022, Mar-14, Volume: 14, Issue:6

    Topics: Equol; Flavones; Genistein; Humans; Male; Prostate; Prostatic Neoplasms

2022
[Equol and its enantiomers inhibited urethane-induced lung cancer in mice].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2022, Apr-18, Volume: 54, Issue:2

    Topics: Animals; Body Weight; Equol; Genistein; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Superoxide Dismutase; Urethane

2022
Estrogenic in vitro evaluation of zearalenone and its phase I and II metabolites in combination with soy isoflavones.
    Archives of toxicology, 2022, Volume: 96, Issue:12

    Topics: Alkaline Phosphatase; Animals; Endocrine Disruptors; Equol; Estrone; Genistein; Humans; Isoflavones; Phytoestrogens; Zearalenone; Zeranol

2022
Urinary phytoestrogens and the risk of uterine leiomyomata in US women.
    BMC women's health, 2023, 05-13, Volume: 23, Issue:1

    Topics: Bayes Theorem; Cross-Sectional Studies; Equol; Female; Genistein; Humans; Leiomyoma; Nutrition Surveys; Phytoestrogens

2023
Systems biology approaches to identify potential targets and inhibitors of the intestinal microbiota to treat depression.
    Scientific reports, 2023, 07-11, Volume: 13, Issue:1

    Topics: Depression; Equol; Gastrointestinal Microbiome; Genistein; Humans; Molecular Docking Simulation; Quercetin; Systems Biology

2023
A UPLC-MS/MS Based Rapid, Sensitive, and Non-Enzymatic Methodology for Quantitation of Dietary Isoflavones in Biological Fluids.
    Molecules (Basel, Switzerland), 2023, Sep-21, Volume: 28, Issue:18

    Topics: Animals; Chromatography, Liquid; Diet; Equol; Genistein; Humans; Isoflavones; Mice; Phytoestrogens; Tandem Mass Spectrometry

2023
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